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<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVA9</accession>
    <name>C7PVA9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TfoX_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0312"/>
    <dbReference type="EnsemblBacteria" id="ACU69265">
        <property type="protein sequence ID" value="ACU69265"/>
        <property type="gene ID" value="Caci_0312"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0312"/>
    <dbReference type="HOGENOM" id="CLU_163277_1_1_11"/>
    <dbReference type="OMA" id="EGNECAH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007077">
        <property type="entry name" value="TfoX_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04994">
        <property type="entry name" value="TfoX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_C" evidence="1">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="101" mass="11158" checksum="1083D5DF654DF6F9" modified="2009-10-13" version="1">MSSTETVTLIQNAVNIGPVLTQRLRDVGVTTLDEVRERGAIEVWQLIAHTAEGNECAHMLLALEGALRGQRWTSIPRSERDALLVEVGLKDASELRAPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVL1</accession>
    <name>C7PVL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNF2-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784662.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0415"/>
    <dbReference type="EnsemblBacteria" id="ACU69367">
        <property type="protein sequence ID" value="ACU69367"/>
        <property type="gene ID" value="Caci_0415"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0415"/>
    <dbReference type="eggNOG" id="COG0553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_17_4_11"/>
    <dbReference type="OMA" id="HRMGQVR"/>
    <dbReference type="OrthoDB" id="325071at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="300"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="543"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="727" mass="79816" checksum="F4926E8A0A1965B4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ9</accession>
    <name>C7PVZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2473</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786684.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2473"/>
    <dbReference type="EnsemblBacteria" id="ACU71391">
        <property type="protein sequence ID" value="ACU71391"/>
        <property type="gene ID" value="Caci_2473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2473"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_1_11"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="5">
        <location>
            <begin position="167"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ETF_alpha" evidence="4">
        <location>
            <begin position="289"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="40987" checksum="1BB1DBA1C8E6342D" modified="2009-10-13" version="1">MAHVVALVEHDAREGTVARSTCALLTLARRLGQPVAACATAPDEETIAVLGRYGATEIWCPDGPAGDAATALPLQRGAAEPAHANAGAGAGAGGDASAGASAGRSVGGDISAGRGIDASASASASAGRSAGGDIGAGRGIDASASASASASAGAGRDVIAGASLSDTDLLAAIAHSLTPAAILIAATHRGQETAARLAIRLDSGIITDAVEVRPGARGPIAVQRCLADSHLVESSVVRGIPIITVCPEAAVPEPSPSEPVLHTVAVEPSPARTPRIVATLKPRPARPALDHADIVVAGGRGIGSQAAFAVLADVAAALGAAVAGSHTAADLGWIPPEARVGLTGKTVNPRLYLACGVSGSVRHRAGMQGAKTVVAIGDDPSAPIFKLADLAVVGDARAILPALLAEILSRTQLRSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW24</accession>
    <name>C7PW24_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4408</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793001.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4408"/>
    <dbReference type="EnsemblBacteria" id="ACU73272">
        <property type="protein sequence ID" value="ACU73272"/>
        <property type="gene ID" value="Caci_4408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4408"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_1_11"/>
    <dbReference type="OMA" id="WSYVAGG"/>
    <dbReference type="OrthoDB" id="1186741at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="314"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="337"/>
            <end position="338"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="41210" checksum="E43C012F680C626D" modified="2009-10-13" version="1">MTDFGAYQYEIYFDGLRGVVPHFPMTYEGWEERARATLSPSLWSYVAGGAGDEHTQRANVAAFSRRALVPRMFVGAKQRDLSVSMFGLTLPSPLMMAPVGVLGLCAQDGHGDLAAARAAARTGVPMIASTLSVDPMEQVAAEFGDTPGFFQLYTPTDRDLAASLVQRAEAAGFQGIVVTLDTWVTGWRPRDLSTSNFPQLRGHCLANYTSDPVFRAALPKPPEEDPGATVMHWAGVFGNPLTWDDLPWLRSLTTLPLIVKGLCHPEDVRRARDGGVDGIYCSNHGGRQANGGLATLDVLPEVVEAADSLPVIFDSGVRSGTDVVKALALGASAVAIGRPYIHGLAIGGVDGLVHVLRSLLAEADLLMAVDGYPTLADLTPDALRTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWP2</accession>
    <name>C7PWP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795051.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6471"/>
    <dbReference type="EnsemblBacteria" id="ACU75322">
        <property type="protein sequence ID" value="ACU75322"/>
        <property type="gene ID" value="Caci_6471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6471"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_10_0_11"/>
    <dbReference type="OMA" id="VMQFQCA"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041678">
        <property type="entry name" value="TetR_C_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17920">
        <property type="entry name" value="TetR_C_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21957" checksum="C199E28E574E78E5" modified="2009-10-13" version="1">MNNRVTAPARTRGRPRGKPPTRESIISAARPLFLENGYRRTTLRAVAAAAGVDAALIAYHFGSKKGLFAHVMQVQCAEALTTGAVLDADPATLADRLIDAVTDLWEDPDFRRLTDQGDEAAQAIGEYLETELLTRLVEFLGGRDATARATAAVTILGGLIYTRYINPLPTPAALTPSQARHALVPALRAALAPRPLVGRNHPAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR4</accession>
    <name>C7PWR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aromatic-ring-hydroxylating dioxygenase beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2020" name="Acta Crystallogr. F Struct. Biol. Commun." volume="76" first="372" last="383">
            <title>Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis.</title>
            <authorList>
                <person name="Vuksanovic N."/>
                <person name="Zhu X."/>
                <person name="Serrano D.A."/>
                <person name="Siitonen V."/>
                <person name="Metsa-Ketela M."/>
                <person name="Melancon C.E."/>
                <person name="Silvaggi N.R."/>
            </authorList>
            <dbReference type="PubMed" id="32744249"/>
            <dbReference type="DOI" id="10.1107/s2053230x20009814"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS)</scope>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795073.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="PDB" id="6P77">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.50 A"/>
        <property type="chains" value="A/B=4-148"/>
    </dbReference>
    <dbReference type="PDB" id="6VW4">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.35 A"/>
        <property type="chains" value="A/B=1-154"/>
    </dbReference>
    <dbReference type="SMR" id="C7PWR4"/>
    <dbReference type="STRING" id="479433.Caci_6494"/>
    <dbReference type="EnsemblBacteria" id="ACU75344">
        <property type="protein sequence ID" value="ACU75344"/>
        <property type="gene ID" value="Caci_6494"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6494"/>
    <dbReference type="eggNOG" id="COG5517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144131_0_0_11"/>
    <dbReference type="OMA" id="RRHWFNM"/>
    <dbReference type="OrthoDB" id="1736098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4 5" id="KW-0002">3D-structure</keyword>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="6P77"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="5">
        <source>
            <dbReference type="PDB" id="6VW4"/>
        </source>
    </evidence>
    <sequence length="154" mass="17507" checksum="4FBCC8CD4BB39EDC" modified="2009-10-13" version="1">MADHWSQAALYAEVQQHQARQMHALDEGKFEEYADTFTPDGVFRHTPGRDPAIGREAIVRELNEFHERYAEDPVQRRHMFTMLAIDELDELDDSAVQADFYTLVLTTRVDGLTVGPSCPVRDVLVRGADGRLLTASRWVEHDNRTVAERTAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXD2</accession>
    <name>C7PXD2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784778.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0540"/>
    <dbReference type="EnsemblBacteria" id="ACU69483">
        <property type="protein sequence ID" value="ACU69483"/>
        <property type="gene ID" value="Caci_0540"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0540"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="PLRIGTF"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="30898" checksum="999A9095AE911679" modified="2009-10-13" version="1">MLDVNRLRLLRELSHRGTIAAVAEALSFTPSAVSQQLSTLEREAGVALLARTGRRVTLTPAGQNLVEHTESVLEHLARAEAELARVRAGLAGPVRIGSYPSAARTLFPAVLTLLARSHPMLEPQITELDPAEVPSALRAGDVDMALVHEYDFVPATSDPGLNSEALFTEPLYLAAPEQGTIADHRDSSWIVSPAGTMCRSSTERACQAAGFSPRVRHEIDDFATAMVLAALGQGVTLVPHLAALAPPEGLTLTRQSMSRRTRIAYRAGTAGHPAVAAVTSALREAVPTDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXH8</accession>
    <name>C7PXH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2513"/>
    <dbReference type="EnsemblBacteria" id="ACU71431">
        <property type="protein sequence ID" value="ACU71431"/>
        <property type="gene ID" value="Caci_2513"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2513"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="TTRMAIM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="10"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="389" mass="42179" checksum="10E807DE611D3952" modified="2009-10-13" version="1">MTALDHEVVLEAEALTKHFPVRARGRAALSRVPKVVHAVDDVSLSLRKGRVTALVGESGSGKSTVARLLAQLYPRTGGDIRIDGVSTAVKGGRQFKAYARRVQLIFQDPFASLNPVHTVRHHLTRALKIHGRYEGEQSLTELLGRVQLTPASLYLDKYPHELSGGQRQRVSIARALAADPEALLADEPVSMLDVSIRLGVLNLLADLKNRLNLAVLYITHDIASARYFADETLVMYAGRMVEGGDSETVTQRPAHPYTHLLVHSAPDPERVRGATEPIDEEDSGEPPSLIDPPSGCRFHPRCPKAMEVCRVRVPERTLVGDAPDHWVACWLFGDEGGENETTALVGKAGDVGEVAEDGDDAELEPMTTVAGLETTSAEPEAPELEGAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI9</accession>
    <name>C7PXI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2524"/>
    <dbReference type="EnsemblBacteria" id="ACU71442">
        <property type="protein sequence ID" value="ACU71442"/>
        <property type="gene ID" value="Caci_2524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2524"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056914_0_0_11"/>
    <dbReference type="OMA" id="NGHIHQV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="57"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="33525" checksum="EA14FB4E7A31BE91" modified="2009-10-13" version="1" precursor="true">MTDELAPGMSRRQLLRHAGWFGSAVVLTVAGGEVVSHIAHDKDSAAAAATAADANALRFVQVSDSHIGFTGPANTDVTASFTEAIDQVNSLGFRPNFVMHTGDLTHLSTAAQFDQVKQMLSEVRTERVFTVPGEHDSVGDSGRAYRQTFGAGTTGDGWYSFDTHGVHFIALVNTLSLEKLGHLGNDQIDFVRKDVAGLSSDTPIVVFSHIPLFAMYPAWGWSTDDSLQVLALLRRFASVTCLNGHVHQLFSKTEGNVTFHSATTTAYPLPAPGKAPAPTPQVLPAGHLKEALGIRTVTYKTGDTALAITDARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXK2</accession>
    <name>C7PXK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional antiterminator, BglG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786748.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2537"/>
    <dbReference type="EnsemblBacteria" id="ACU71455">
        <property type="protein sequence ID" value="ACU71455"/>
        <property type="gene ID" value="Caci_2537"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2537"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1812300_0_0_11"/>
    <dbReference type="OrthoDB" id="1036370at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="16519" checksum="CAB52602D172AB3D" modified="2009-10-13" version="1">MPDTATWSNRLGSDHSEALANLVAGLTDHASAHRLGVSERTVQRRIRELMDWSSSANRMQLGHRAALAAVGDLSCLPLPRRRLPELPAGHTPDEAAMHLLRLLLADAAADRTLNMSASSIERRIRELMKLAGARSRAQLGWRATWWGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXX0</accession>
    <name>C7PXX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4568</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4568"/>
    <dbReference type="EnsemblBacteria" id="ACU73430">
        <property type="protein sequence ID" value="ACU73430"/>
        <property type="gene ID" value="Caci_4568"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4568"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_3_11"/>
    <dbReference type="OMA" id="ARFENEN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="48"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="4">
        <location>
            <begin position="402"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="224"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="85"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="517" mass="54012" checksum="EAA40BF594B84548" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY7</accession>
    <name>C7PXY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793176.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4585"/>
    <dbReference type="EnsemblBacteria" id="ACU73447">
        <property type="protein sequence ID" value="ACU73447"/>
        <property type="gene ID" value="Caci_4585"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4585"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_0_2_11"/>
    <dbReference type="OrthoDB" id="1152952at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="30"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24727" checksum="D10F85E2A1742060" modified="2009-10-13" version="1">MSEQPPAADRPRVLFIVSAAHQLTMKDATLLTTGFWAEELLVPHQAFTQAGFDVKFATPAGLVPQPDPRSLNAHDGAELDHLPDLRTPLVLDDVELDGYEALFVPGGHAPLEDLATDRVAGTLITDALTAGKPVGAVCHGPAAFLAAHRPDGTPAIAGYRITAFTDEEERQGGLADNMRYLLEDKLVELGADFVQGPAFHEHTETDRNLHTGQNPQSSAQIAADMLEALGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYU4</accession>
    <name>C7PYU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8597</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8597"/>
    <dbReference type="EnsemblBacteria" id="ACU77416">
        <property type="protein sequence ID" value="ACU77416"/>
        <property type="gene ID" value="Caci_8597"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8597"/>
    <dbReference type="eggNOG" id="COG2064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079642_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="146"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29635" checksum="37353E4D54789BBF" modified="2009-10-13" version="1" precursor="true">MVVMLAGALFGAGLMVGWLAFRLPAEASATCELADDTMYADAEWLARMGRPLARKLIVLGLPRDSIRRDLVVLDRVPEVHLAAQTAATLAGFLLSWLLQSVLDFSLPFTGFLSIAVAGVFWYLVDADATAKAAEARADALADLSVFLDVTVNALAAGTGVEQALGGASEIGDSPAFERLRHALDVAFLSRLPIHQVFAELGTTLGLAEITDLAASLQLAGAEGAKIRTSLAAKAEAIRAKILADEEAEAAATTERMTVPIALLMTGFLVLIGYPAMASALSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYV8</accession>
    <name>C7PYV8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Caci_0577</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0577"/>
    <dbReference type="EnsemblBacteria" id="ACU69514">
        <property type="protein sequence ID" value="ACU69514"/>
        <property type="gene ID" value="Caci_0577"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0577"/>
    <dbReference type="eggNOG" id="COG0543">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026437_2_1_11"/>
    <dbReference type="OMA" id="WWHTIPA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="17" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="18">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="19">
        <location>
            <begin position="138"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU69514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="40063" checksum="5C68CA65E58C3A06" modified="2009-10-13" version="1">MDPHLLRTSWAKVAQYGEQVPLFFYGHLFLSHPEVRAMFPPSMAAQRDRLVAALGAVVANVDNLDSAVPFLQGLGRDHRKFAVEPGHYPAVGASLLATLEQFLGPDWTPAVAESWTEAYGIVAKVMTDAAAAASESTPPWWEAEIVAHEVVGGRRDIARVTIATRQPYAYTAGQSMTLETAMAPARWRFYTPANPPRQDGLIELHIKLVGAVSWQLVNIMGVGDRLRLGPPVGYQLTLASTAPGTDLLLIAGSTGVAPLRAIVEELARTPDHGRHVTLFYGARIGSDLYDLPRLEQLAAHHGWLSVIPVVSDDHAWEGRHGLVGDIAAAYGNWPGHEVFIVGSAGMCEHTAARLKEAGVIPGAIHLEESQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZB7</accession>
    <name>C7PZB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ACU71574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2658"/>
    <dbReference type="EnsemblBacteria" id="ACU71574">
        <property type="protein sequence ID" value="ACU71574"/>
        <property type="gene ID" value="Caci_2658"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2658"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="IHEEWER"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
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        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
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        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
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        <location>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="739"/>
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        </location>
    </feature>
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        <location>
            <begin position="774"/>
            <end position="798"/>
        </location>
    </feature>
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            <begin position="211"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="460"/>
            <end position="565"/>
        </location>
    </feature>
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        <location>
            <begin position="470"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU71574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="841" mass="84515" checksum="B78B84BC1F6EE8EA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZG8</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ACU71625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ACU71625">
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        <property type="gene ID" value="Caci_2710"/>
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    <dbReference type="eggNOG" id="COG1012">
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    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="QAYGQIA"/>
    <dbReference type="OrthoDB" id="744602at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ALDH_AldA-AAD23400"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="FUS7/LUC3-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <end position="452"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="467" mass="49288" checksum="D376A30E818FEA84" modified="2009-10-13" version="1">MPTTEPSRPHRARGGSFAVLDPATGEPFAEAPDQQPEELDAIVERAHTAWRGWRADPDARAAALLAAADAVERAGPDLAPLLTREQGKPLPESFAEVARAAARLRYFATLRPQTRPIVDGRPVRSEVRWRPLGPVAAIVPWNFPLQLASAKFAPALAAGNTVVLKPSPFTPLATRMLGSVLAAALPEDVLTIVTGREPLGERLASHPGFGHVTFTGSVPTGRAVARGAASSLARVTLELGGNDAAILLDDVDVEQIVDRLFWAAFRNCGQICMAVKRVYAPARLYAEVVEALAQRADQTVVGPGLQAGSQLGPVNNAPQLARVEGYAAEALATGARAAAGGHRLDRPGYFFAPTILADVSAQSPVVAQEQFGPVLPVLVYRGVEQAVEAANATGFGLGGSVWGTDLDRAEEVAERLECGTVWINHHGELSLAQPFAGAKDSGVGVAGGPWGFYGNLRPFVVHRPEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS8</accession>
    <name>C7PZS8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4732</name>
    </gene>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU73593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4732"/>
    <dbReference type="EnsemblBacteria" id="ACU73593">
        <property type="protein sequence ID" value="ACU73593"/>
        <property type="gene ID" value="Caci_4732"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4732"/>
    <dbReference type="eggNOG" id="COG1975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041115_1_0_11"/>
    <dbReference type="OMA" id="HTPIHHD"/>
    <dbReference type="OrthoDB" id="1879870at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="201"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="307"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="49336" checksum="EE5417A6FC976315" modified="2009-10-13" version="1">MRDITEDLHAWHTAGKPYALASVVAVKGSAPRELGAALAVDTDGTVVGSVSGGCVEGAVYELCVESLQHGRPVLETFGYSDDDAFAVGLTCGGELEVFIQPVFPDQGSTADQAIGTAVPAMTAGEPSARPGLAVGTAVPAVTAGEPSARPDLAVGTALPAMTAGEPSARPELAVGTALPAMIAGEPNARPDLAVGVVLSAMAAGEPVALARVVAGPAELVGRSLAVRPQAPEILWGPPGASIAVDGDPWSATGAISPALDRVVARHARAMVESGATGTVAVGTEGEGQDCGEAVTVFIESFVTAPRMLVFGAIDFAAALVRVGKYLGYHVTVCDARPVFATRRRFPEADDVVVAWPHRYLETTRVDARTVIAVLTHDAKFDVPLLVKALRLPVGYVGAMGSRRTCAQRADRLREAGLSDAEIANLHAPIGLDLGARTSEETALSIAAEIVAARHGGTGRSLADVSTAIHHTPAAHPVESGVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q015</accession>
    <name>C7Q015_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hopanoid biosynthesis associated radical SAM protein HpnH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795237.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6662"/>
    <dbReference type="EnsemblBacteria" id="ACU75508">
        <property type="protein sequence ID" value="ACU75508"/>
        <property type="gene ID" value="Caci_6662"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6662"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052502_0_0_11"/>
    <dbReference type="OMA" id="FNTDTPQ"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022563">
        <property type="entry name" value="DUF3463"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017833">
        <property type="entry name" value="Hopanoid_synth-assoc_rSAM_HpnH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11946">
        <property type="entry name" value="DUF3463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00397">
        <property type="entry name" value="adenosyl-hopene_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03470">
        <property type="entry name" value="HpnH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="22"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="38155" checksum="4EF4A0C1D573AD14" modified="2009-10-13" version="1">MGMPVRQSIRIGSYVLGNKLRRREKFPLLVELEPLFACNLACAGCGKIQHPADVLKKRMPVEQALAAMRECGAPMVSIAGGEPLMHPQIGELVDELVKMKRYVFLCTNALLIPKKLDRFKPSRYFTWVVHLDGLRERHDESVCKEGVFDEAVAAVRELRRRGFRVTTNTTIFDTDSPQDVIDILDYLNDDLRVDQMMISPGYAYEKAPDQQHFLPVKQTRELFHKAFSNGNRERWRLNHSPLFLDFLEGKTDFPCTAWAIPSYSLFGWQKPCYLMSDGYAATYKELLEETDWDSYGRGNDPRCANCMAHCGYEPTAVFATLGSLRESVRALRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0N6</accession>
    <name>C7Q0N6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low temperature requirement A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784959.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0729"/>
    <dbReference type="EnsemblBacteria" id="ACU69664">
        <property type="protein sequence ID" value="ACU69664"/>
        <property type="gene ID" value="Caci_0729"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0729"/>
    <dbReference type="eggNOG" id="COG4292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045667_0_0_11"/>
    <dbReference type="OMA" id="HMAERCA"/>
    <dbReference type="OrthoDB" id="886435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="PTHR36840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="44436" checksum="05CA6F2CB6769E3F" modified="2009-10-13" version="1">MASTPVVLIRPILLRDPTEQGRTATTLELFFDLVFVVTISTIAQQWHHAVIDGHLEHGIISFVEMMFGVWWAWMGFTWFANFFDPDDVPYRLLVLVQLLASLGLASGIPYVFESDDFRIVVGCYVMIRLVMAAQWLRASHANPELRPFCNRWAYGILGVQVGWVVFGFGIRDLTPLQTIPFFILGALIELLVPAWAEAAEGAPLPHSEHVEERYGLFTIIILGEMVLVASEAFNTALSDHQHLATLMVGAISAGVLAFCLWWLYFGFLGEFDLTRVRITFVWGYGHYFIYGTLTAIGGTLAALLDQVARGGGALSHTVMALMLAVPVAGFLTAMALLRRVSEWSGASRWLVGAAAVLLVGTGAGAAWGAMWTLLSVCVATAAFLASEIVTKWKAAVRRRQNQGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Z9</accession>
    <name>C7Q0Z9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786967.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2761"/>
    <dbReference type="EnsemblBacteria" id="ACU71674">
        <property type="protein sequence ID" value="ACU71674"/>
        <property type="gene ID" value="Caci_2761"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2761"/>
    <dbReference type="eggNOG" id="COG4101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090057_1_1_11"/>
    <dbReference type="OMA" id="WKHDGVR"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14931" checksum="2EDB21CB6703E728" modified="2009-10-13" version="1">MTDHWHAPLRHIKAADLSGNTGQTSGMTRLEAVSGKTVGAEKVWMGQTHVAPDTNSGDHHHGEAETAIYVVSGNPVFVFAEGEEEVRIQTGPGDYVFVPPFVPHREENPNAEEAVVVIARSSQEGIVVNLPSLWAPVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1N1</accession>
    <name>C7Q1N1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol phosphodiesterase</fullName>
            <ecNumber evidence="2">4.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Phosphatidylinositol diacylglycerol-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphatidylinositol-specific phospholipase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol</text>
            <dbReference type="Rhea" id="RHEA:17093"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58484"/>
            <dbReference type="EC" id="4.6.1.13"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.6.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795311.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6736"/>
    <dbReference type="EnsemblBacteria" id="ACU75582">
        <property type="protein sequence ID" value="ACU75582"/>
        <property type="gene ID" value="Caci_6736"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6736"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024117_3_0_11"/>
    <dbReference type="OMA" id="LYVMHGV"/>
    <dbReference type="OrthoDB" id="941044at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004436">
        <property type="term" value="F:phosphatidylinositol diacylglycerol-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982792" description="1-phosphatidylinositol phosphodiesterase" evidence="6">
        <location>
            <begin position="32"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PLCXc" evidence="7">
        <location>
            <begin position="49"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="35451" checksum="B6DE3F5107B9A0FD" modified="2009-10-13" version="1" precursor="true">MNPTRRNVLKWGLSGTVLAATSLGLPATARADSPVTPGGKPTDRWMSYLDPNLSLLGMTVPGTHDTCCTNPANGTEWSHTQNWGIPQQLSEGVRFVDIRCNGLQGTASEMGIYHSSYYQGIRLQDVLDQCKAFLASQPTETIVMRLKNENAGGQALSDAEFQRRVTYYFDTLGYRDLFHMYGWPTLGQAAGKVVLLADFAFPASWNLIGWADSANWQFNVQDTYTGVSTGSKGQLITQQFDNAYSNPAPTTMYVNFLSLAPSINDGLGFPKNLEQTLMDNSIYPYLRARTGQRARFGIVPMDFPDFHVNVLEMLIDKNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Q6</accession>
    <name>C7Q1Q6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6762"/>
    <dbReference type="EnsemblBacteria" id="ACU75607">
        <property type="protein sequence ID" value="ACU75607"/>
        <property type="gene ID" value="Caci_6762"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6762"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="NLANDRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="116"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="20156" checksum="0A482E7256A27FE1" modified="2009-10-13" version="1">MAHDTTERLRGFEEFVATRSQSLMRTAFLLVGTREGAEDLVQSALEKTFPRWSRVRRMDTPEAYVRRIVVNNAHAAWRSAKRLPTVELPGGSDSPALAAASVATAAGDHAEDVTLRDSLLRALDELPHGMRTIVVLRYWEELSVQEVAELRRCSAGTVKSQAARGLARLRELMTAEARSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V8</accession>
    <name>C7Q1V8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795387.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6818"/>
    <dbReference type="EnsemblBacteria" id="ACU75659">
        <property type="protein sequence ID" value="ACU75659"/>
        <property type="gene ID" value="Caci_6818"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6818"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="TFITETH"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="31077" checksum="579E7185AFAE1B19" modified="2009-10-13" version="1">MEDRLVRAFVAVADHGTFGAGARALAVTQPALTKQIQALEARIGGVLFRRGRLGARLTPLGQTLLPDARDAVERLDAFELRAKRLTAGGAGRLALGFGLSTIDIAPRAVAEFRRRHPDVGVTLDDMATAVQLERLRRGQLDAGFVRLPVDPDLSVLELGADHLMLAVPGNVDTSPGVRELIMTHGMVALAQTKGPGFVDQVQRYLAAEGIRPRVLQRANDLQTVMALVAAGVGVALVSARAPVVVAAERIRWVPIEHEAARWGVGVVWGGGGGEAAPALAAFLDVTRELAAGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y1</accession>
    <name>C7Q1Y1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6841"/>
    <dbReference type="EnsemblBacteria" id="ACU75682">
        <property type="protein sequence ID" value="ACU75682"/>
        <property type="gene ID" value="Caci_6841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6841"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048112_0_0_11"/>
    <dbReference type="OMA" id="RKRAIFH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="234"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="492" mass="54640" checksum="643F5331476EB2A2" modified="2009-10-13" version="1">MQSLDVRVWSITPIKLANRTTYKVRWGVAGRTFSKTYASKQLAESRRSELLTAQRRGEAFDRDRGLPESEIRAMLASVSWYQNAIEFMDTVWPGLEPGSRRKLAESLATVTLALTEPGIDPVDHAFCFRWLVRWAFNSRERMTAALDGEAAFVVQWIADHSLPMSALADPKVARRAFNSTTTDCFGRPYAVNTYRNKKKGLNGAISFAIEMGRLDANPLERISTTPPKHKSSVDRTAVVNPAQARLLIERVREQGPTAPRLVAFFAVLYFAGLRPSEALALRVSDCDLPDVGWGSLRFAESVPYANAAWTDDGETSPRKSLKHRAQGQSRMVPACPELVRYLAAHIEKFGAAPDGRLFFRLDGGPIRHSTYAKIWARARAAALTPDQCRSQLGRRPYDLRHAAVSTWLNAGVPATQVAEWAGHSVEILLSTYAKCIDGPDQDELARRRIDAALGSADGAVDQGAARESQDRNRTQTAADDDPQRETVRHRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J2</accession>
    <name>C7Q2J2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GtrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_0902</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GtrA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785129.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0902"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69834">
        <property type="protein sequence ID" value="ACU69834"/>
        <property type="gene ID" value="Caci_0902"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0902"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_3_0_11"/>
    <dbReference type="OMA" id="FFDTEML"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="9">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="10">
        <location>
            <begin position="285"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="46059" checksum="ED49F6C96CD10B32" modified="2009-10-13" version="1">MNATALTDREPPDAGTGAAGAPRRRLVEVVVPVYNEQHVLETSVRRLHRYLVENLPYPFRITVADNASTDGTWAVAARLSRELSGVRAVHLDLKGRGRALRAVWSASDADVVSYMDVDLSTDLNAFLPLVAPLLTGHSDLAIGTRLARGSAVARGPKREFISRTYNFLLRTTMAARFSDAQCGFKAAKTEVVQALLPRVQDEEWFFDTELLLLAERSGLRIHEVPVDWIDDPDSRVDIVKTAKADLRGMWRVAKASLSSSSGAPVRARVRAADPPPGLKWQIPVFATIGVLSTLAYLLLYVLLAAPMGAFAANAIALAVTAVANTAANRRFTFGVTGSRNALRDQIGGLVAFGIGLVLSTGTLAAVHAAVHHPSRTTELAALIVANGLSTLARFVLLRAWVFHPRHHPRPSADHETAVAAGQTSGELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q374</accession>
    <name>C7Q374_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793539.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4950"/>
    <dbReference type="EnsemblBacteria" id="ACU73810">
        <property type="protein sequence ID" value="ACU73810"/>
        <property type="gene ID" value="Caci_4950"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4950"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_11"/>
    <dbReference type="OMA" id="THCENRT"/>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="9"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="36640" checksum="25DC45B6A2FFDDE7" modified="2009-10-13" version="1">MTSLAVRYTAARTLTTGPAAPVPPGPGQVELAPAYVGICGTDLHIFHGDMDGRVKAPAVIGHEMSGHVVRVGPGVEGYAPGDPVTVMPLSWDGTCPACLNGHRHICQNLDFIGIDSPGAMQQRWTVPASTLIRLPESLALDRAALVEPTAVAVHDVGRAGVSDGDRVVVVGGGPVGLLIALVARASGGEVRVVEPNPQRRRLAEQLGLNTWDPGADDVPERVRDWTQDAGADIAFEVSGAEAGVQTAVDVLAVRGRLCLVAIHPRPRAVDLHRFFWRELTLIGARLYERQDFETAVRLIDEGTIPAEQLISRIVPLVDALDAFTSLESGGDVKVLVDCGNTSPEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q385</accession>
    <name>C7Q385_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793550.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4961"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73821">
        <property type="protein sequence ID" value="ACU73821"/>
        <property type="gene ID" value="Caci_4961"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4961"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002346_0_2_11"/>
    <dbReference type="OMA" id="SNWQLQG"/>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901575">
        <property type="term" value="P:organic substance catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="7">
        <location>
            <begin position="724"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1018" mass="112887" checksum="1BB6C507E6AC3F61" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q484</accession>
    <name>C7Q484_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785238.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1016"/>
    <dbReference type="EnsemblBacteria" id="ACU69944">
        <property type="protein sequence ID" value="ACU69944"/>
        <property type="gene ID" value="Caci_1016"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1016"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_2_11"/>
    <dbReference type="OMA" id="NILHHWC"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="34747" checksum="52B699011CCEE6F9" modified="2009-10-13" version="1">MPQWSPEEMPDLTGRVAMVTGASSGIGFHTALELARHGARTLLAVRDPSRGEYARERITAVVPSARGLVEIVAVDLASLESIEDAAADLADRTAAVDILVNNAGVMVPDGHTTSDGFELQFGTNHLGHFALTGRVLPLLLAAESARVVTISSLTHRRARPFWDFEPATANSKESYTEAEWHRHRVSAYGRSKLANLLFAKELDRKAKQARFPLASIAAHPGYTATGLFAKTSFSRRNRVVSGLSHMVTWATGQSAATGAWPSLYAATHVDLFGGEYIGPRGPGEMRGAPTRAVMSAIAQDETVAAILWDQSVAATGVGYEELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4A5</accession>
    <name>C7Q4A5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1039"/>
    <dbReference type="EnsemblBacteria" id="ACU69965">
        <property type="protein sequence ID" value="ACU69965"/>
        <property type="gene ID" value="Caci_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1039"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_23_2_11"/>
    <dbReference type="OMA" id="FYRHFRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="21537" checksum="8D770CC26D87AE91" modified="2009-10-13" version="1">MHADTDESVTRPSSGPGTRARILAAASELFYGQGIRATSADRIIEQVGITKVTFYRHFRTKSDLVVAYLKEQAAAERGWMESTRREGDPVGSLRTLATGIGAASCRPGFRGCAFINAAAEFADPDDPVRAVVDEHRGWMLSEFGAIAAEAGASDAGAIARELMLLRDGAMVNGYLGDPAAVADSLAAAFTAIMATVEAAAVEAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4I1</accession>
    <name>C7Q4I1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gp37Gp68 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787243.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3041"/>
    <dbReference type="EnsemblBacteria" id="ACU71950">
        <property type="protein sequence ID" value="ACU71950"/>
        <property type="gene ID" value="Caci_3041"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3041"/>
    <dbReference type="eggNOG" id="COG4422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054184_0_0_11"/>
    <dbReference type="OMA" id="WADIRIP"/>
    <dbReference type="OrthoDB" id="979208at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011101">
        <property type="entry name" value="DUF5131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07505">
        <property type="entry name" value="DUF5131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="33863" checksum="F2C52000CCB46C11" modified="2009-10-13" version="1">MSAKTKIQWTMSDDGTPGATWNPITGCTKVSDGCLKCYITGTPPFRIAHRKFDKPGIGGTTGILFHPERLSAPLHWRKPRRVFVNSLSDLFHEDVPTEYIARVFAVMAKTPQHVYQVLSKRHGRMRSLLRDGGQALLEATNDEDTASALYDAPWPLPNVWLGVSTEDQHTANLRIPALLETPAAIRFISAEPLLGPIDLQHLEARGVIMDALGGDVSFPGTGEIFTGTPSILDWIIAGGESGPGARPMDPAWVASIVEQCRPGVNHAFVKQLGSVWAKANGAADRKGGDLEEWPAELRVRQFPQAEMAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5D9</accession>
    <name>C7Q5D9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7078"/>
    <dbReference type="EnsemblBacteria" id="ACU75908">
        <property type="protein sequence ID" value="ACU75908"/>
        <property type="gene ID" value="Caci_7078"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7078"/>
    <dbReference type="eggNOG" id="COG1555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717064_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="239"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="39463" checksum="69B639FDCC2CBD93" modified="2009-10-13" version="1">MPLSEALAARHHAHRPWWRRAAQSIEHRVPATLHGRWALSLPAATAVAVVAIGGAAAGGWYLTRSQSTVVDVAGKAGDAASATPAPDDDHPMPSAEGGDSVKAGGVAAEHDGACRTHARPSGSPQALPPVTAPTGWHMRALSVMAADARPASATGWHESILTVVPIAAHPAASPSGQRARTVTIVPVVADPALARNWSHAPLTRRYAKAMAAKRPSCPPHTAMSTTPAVAGPAAGSEVVVDVEGKVARPGIATLPAGSRVYEALAAAGGALPGVDVTALDLARPVTDGEQLRVGIAGAPSPVVGLPQPSSSGAAHGKRGKTTQPVNLNTATLEQLETVPAVGPALAQRILDWRTEHGRFESVAQLRQVRGIGDRKFADMRDSVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5M1</accession>
    <name>C7Q5M1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_9019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797556.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9019"/>
    <dbReference type="EnsemblBacteria" id="ACU77832">
        <property type="protein sequence ID" value="ACU77832"/>
        <property type="gene ID" value="Caci_9019"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9019"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060923_0_0_11"/>
    <dbReference type="OMA" id="HRHHAYT"/>
    <dbReference type="OrthoDB" id="1574388at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="117"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="35221" checksum="CDB0F81C2CDE5276" modified="2009-10-13" version="1" precursor="true">MSVNVYLPLLAAVALGAAGPALGRRLPPAVATVLLTAAALVTSFTSLASLALLTGVVVLRIPEFAAEGRLSDAVLMHGPVTPLEGAVAGTALLALLPFAIRAGIRLWRESARTYRLAKAFSAHPASIAVIQDPRAQAFAVPGIPSLPGHAAIPTRIVATDSLLRTLNEDQRRAMFAHEQAHLRRRHHLYLLLTNLAVVANPLLWRLPDAVTEATERWADEDAAVAVGDREVLARALGRAALSNLPRTVPAMAQAHVGKRVRALMAPPPPRRRVLAALVGFAIAATVFASIDSARETEDFFDNARDAWHVAHEHPVAEHPQLVVSPTVGGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D8</accession>
    <name>C7Q6D8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3237"/>
    <dbReference type="EnsemblBacteria" id="ACU72144">
        <property type="protein sequence ID" value="ACU72144"/>
        <property type="gene ID" value="Caci_3237"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3237"/>
    <dbReference type="eggNOG" id="COG2856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104213_2_0_11"/>
    <dbReference type="OMA" id="VAHQAHI"/>
    <dbReference type="OrthoDB" id="1877942at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18689" checksum="4BFE39DE7AB98D3F" modified="2009-10-13" version="1">MGAGGGRTGLWRRCQAVVDRLDLPDPFDAETFIAGLARKRGRPIELIGVPARPDRPCGLLVTTARTDLIIYSSDTSSVHRRHILLHEAAHLVRGHDAAGAGSAAAGLGTLLPHLSPSLIRSVLGRTVYTEPQEREAELIATMIHHRAARGRPPLGRSVPPRHRIETMFGLGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F5</accession>
    <name>C7Q6F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3254"/>
    <dbReference type="EnsemblBacteria" id="ACU72161">
        <property type="protein sequence ID" value="ACU72161"/>
        <property type="gene ID" value="Caci_3254"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3254"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095237_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="25989" checksum="FF0A53DF08986F1A" modified="2009-10-13" version="1" precursor="true">MNQTTEALATVPEQKAPAGASQNLPTDLTDLTGTPRRATAAISAATEDEAAAAGLAIRAEARWPESGLDDAAPALPGFIVSSFSPIAAETAARCLSRRAAHAPENETKAFEDPETSEARAQAQAHTPVTAILITTARGDRESASHVARTVAANGLLGPLLFFQSVPNAVAGHIAARWKLTGPVVCLADPASALETAALLIEDGDADEALLVRIEQNPSGPDQAHAVLLAALTAHPAPSPAPQAKAPAPTTPGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T6</accession>
    <name>C7Q6T6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795677.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7119"/>
    <dbReference type="EnsemblBacteria" id="ACU75949">
        <property type="protein sequence ID" value="ACU75949"/>
        <property type="gene ID" value="Caci_7119"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7119"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_4_1_11"/>
    <dbReference type="OMA" id="TKQYVAQ"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_cpsA_psr" evidence="2">
        <location>
            <begin position="79"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="39193" checksum="DAF82CDA15373989" modified="2009-10-13" version="1" precursor="true">MSMSVLLISLTGAWLRAAVLGGFQRSAALGGTIPKSHDGSVNILLMGLDSRRDNHGHDLPAAILSKLHAGSSSDIGGYNTNTLILLHVPADGSPATAVSVPRDDWVDIPNLGWHKIKEAYGRAKAAQETALVKAGRGPTGDALEAAGREAGRAASIAAVQGLLNVPIDHFAEVNLAGFYDVAVALGGVTVCLNKPVQDDYSGAAFPAGVQTLDGSNALAFVRQRHGLPGGDLDRTRRQQAFLSAVQRKLSADGVLSDVGKLSDLVDAVKRDVVVDDSFDVLSLISKAGSLKAGRIQFHTLPIEGFATRDGEDVNLIDPAKVQAAMKEYFSDATSGGSSGGSGTHPTSVVQAASAATALATTAAPKSGSGSDATTKNGIACVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T7</accession>
    <name>C7Q6T7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7120"/>
    <dbReference type="EnsemblBacteria" id="ACU75950">
        <property type="protein sequence ID" value="ACU75950"/>
        <property type="gene ID" value="Caci_7120"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7120"/>
    <dbReference type="eggNOG" id="COG4420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914290_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="34217" checksum="EE0E3437AB0194DA" modified="2009-10-13" version="1">MTHYLTSLALLYASVSLYTSMRHPHVHMRLRHGHARVEHEFAGAGGRLAAWITRRLGSMWTVYVCVALTMAWILLGSRTFLGFDPYPYPFMLFLGNMAQLLLIFVILLGQQVLGRTGDRRAIQTFEDAEAILHDCEQIQNHLIAQDAHLAACVVLDELEQFQLTAAAERFTTPPTMADEHISANARLAARITARCGTMSAFYIAAAFQMVWIVLAQTGVLRFDKYPFAFLLFLSSLAQLLLMFVIMLGQQVLGRAADRRAEMTFRDAEAVLRACERLQAHLRAQDLAIRHVVDHMTTCGSAEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T9</accession>
    <name>C7Q6T9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795680.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7122"/>
    <dbReference type="EnsemblBacteria" id="ACU75952">
        <property type="protein sequence ID" value="ACU75952"/>
        <property type="gene ID" value="Caci_7122"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7122"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="IMAIRFE"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="106"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="32388" checksum="72EEA0DE40AE22B2" modified="2009-10-13" version="1">MNPAATDTFVGLRNLLFTVAYEILGSAADAEDVLQETWLRWVEVDLEQVRDERAYLIRITTRQALNRLRTMKRRREAYVGTWLPEPLLTAPDVAEHVEVAENLSIALMLVLETLSPTERAVFVLREAFDVGYDEIAEAVGKTPAAVRQIAHRARQHVDARRPRTTATQRTAQAAVAAFQRALETQDVQALMDVLAPQAVLIGDGGGIKRAGLRPVTGAAKVIRYVLGGIRKSGVTVTTELTDVNGNPGLLVRVDGEVDGIMALHVEDDRIAGMYYVLNPEKLTRVGGETEVAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V1</accession>
    <name>C7Q6V1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795692.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7134"/>
    <dbReference type="EnsemblBacteria" id="ACU75964">
        <property type="protein sequence ID" value="ACU75964"/>
        <property type="gene ID" value="Caci_7134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7134"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_1_11"/>
    <dbReference type="OMA" id="FHYFPAG"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="22044" checksum="FB4E7BB87E8D965F" modified="2009-10-13" version="1">MSGVAGTVLTAKGRATRARIVEGAAEVLRETGVDLATLDDVMARTHTSKSQLFHYFPAGKDELLLAVAGYEADRVMEHQEPYLGCLDTWEAWERWRDATVQRYEEQGDRCPLGTLSLYLGRSTPGARAVVVTLLRQWQAALAVGVRALQEAGRLPASVDADERAAALLAAIQGGVGILLATGDAYHLRVALFQGVADLRRLATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q730</accession>
    <name>C7Q730_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795771.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7214"/>
    <dbReference type="EnsemblBacteria" id="ACU76043">
        <property type="protein sequence ID" value="ACU76043"/>
        <property type="gene ID" value="Caci_7214"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7214"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085079_0_0_11"/>
    <dbReference type="OMA" id="WIRVPGH"/>
    <dbReference type="OrthoDB" id="1824772at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="26190" checksum="5A4B7E136272F4E0" modified="2009-10-13" version="1">MGGIVNDLPEYRSVLAVDIEKSSGRGNQALLAIRAALTRCLSEAVERSGIAWDACLVEDLGDGLRVTTPSGTARTSLVHPLIPELAARLREHNRLHAAIGQIRVRMAVHSGDVFVGPQGVPAGSSLIVLARMLDARACRDALAKAPESVPLVLLVSQHFYDETIVHGYVGIEAAEFRRVQVEEKEYAAGAWLYVPQGVSVQEDEAAARAAPASSPGSDDRSSMTVIATDSAKALGVQHGDVHIHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q761</accession>
    <name>C7Q761_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.157" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785443.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1224"/>
    <dbReference type="EnsemblBacteria" id="ACU70149">
        <property type="protein sequence ID" value="ACU70149"/>
        <property type="gene ID" value="Caci_1224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1224"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="CKLGFGH"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980662" evidence="4">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="5">
        <location>
            <begin position="187"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30021" checksum="CBE449DBB153F056" modified="2009-10-13" version="1" precursor="true">MSKKLAVIGAGLMGSGIAQVAAAAGYEVALRDVTDAALKRGADGIRASLEKFASKGRYTAEEVEAATARVSTTTDLAEAVADADVIVEAVFENAEVKQDIFRELDKLAKPGAVLATNTSAIPITQIAAVTSRPQDVIGTHFFSPVPMMQLCELVRGYKTSDETLAKARAFAEETGKTCIVVNRDVAGFVTTRLITALVVEAVKLYESGVATAEDIDLACKLGFGHTMGPLATADLTGVDILRDATRNIYTETQDEKFSPPELMNRMVTAGDLGRKSGKGFYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K1</accession>
    <name>C7Q7K1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787487.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3287"/>
    <dbReference type="EnsemblBacteria" id="ACU72194">
        <property type="protein sequence ID" value="ACU72194"/>
        <property type="gene ID" value="Caci_3287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3287"/>
    <dbReference type="eggNOG" id="COG4188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066851_1_0_11"/>
    <dbReference type="OMA" id="RLTWAYL"/>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="33214" checksum="ABBDFA2071793AB9" modified="2009-10-13" version="1">MSPSHVSTPPVLSYSPVVLSVPGRPVDLELRVTAPVEGADLPVILLSHGHGGSNNLSSLYGYAPLANAWAALGFAVIQPTHLSSRTLSSRVADLPGAPLFWRSRAEDMTHILDRLDAIEKAVPLLAGRLDAAKVAVAGHSLGGFTASVLLGAQVTDPDTGEVVDLAEPRIKAGVLLAAPGRGGEALTGPRASIVPFFRSVDFATMTAPALVVAGDQDDSRHFTDVGPQWHADPYTLAPGPKTLLTLFGAEHGLGGIAGYDAAETTDENPDRVAAVARLTAAYLRSQLFGGDGDGDSGDGDAFEAACQALTTGPDAFGRVDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K4</accession>
    <name>C7Q7K4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase, PHB depolymerase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787490.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3290"/>
    <dbReference type="EnsemblBacteria" id="ACU72197">
        <property type="protein sequence ID" value="ACU72197"/>
        <property type="gene ID" value="Caci_3290"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3290"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_0_0_11"/>
    <dbReference type="OMA" id="VAIWHGT"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="46605" checksum="69E6E266587E9C3A" modified="2009-10-13" version="1" precursor="true">MPHTPTPSPTPAPPRTAGRRRGILASLAAAFLTLAASALTLAPSGAPPARAASSLNQVTGFGSNPGNLAMYSYVPQGLPQGAPVVVALHGCTQTASDYYTHSGWSQLADQWGFAVVFPQTSSTNNSLSCFSWFDSTKDTRGKGEAASVTQMVSYAESHYGSDSHRVFVTGLSAGAGMTADLLADYPDVFAGGAIDSGLPAQCATTQTAASSCQMNNQNFTPAQWGDKVRNSDPGYTGPWPRVAIWQGSADYTVYPVNATELRDQWTNVWGISQTASSTQSLSGGTTESVYNDKNGKPAVEMYSISGMGHGLAVDPGSGTAQCGSTGAYFLSYICSSYYTATFWGLNSGTPPTSTPSTTPSTTPSTTPSTTPSSPTSTPSTHPSSSSSSSAPAPCFTASNYAQTVAGRAYQSGGYTYADGSNQNMGLWNVLVTHTLKETSAGYYVIADSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7S8</accession>
    <name>C7Q7S8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787564.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3364"/>
    <dbReference type="ESTHER" id="catad-c7q7s8">
        <property type="family name" value="A85-Est-Putative"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72271">
        <property type="protein sequence ID" value="ACU72271"/>
        <property type="gene ID" value="Caci_3364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3364"/>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037947_0_1_11"/>
    <dbReference type="OMA" id="HLTSTWE"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982614" evidence="3">
        <location>
            <begin position="22"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="42454" checksum="31781D1026B5A981" modified="2009-10-13" version="1" precursor="true">MSLTSTALLILAVCSAVAAPAATYVLWNRARGPRPVRAAARLGLIGLCQATMLLLVGLLVNNHYSLYASWSDLLGQDGGGPVAVRQATDAATDLNHPVTSSTDSRGRFGFGGHGQGSHSTPPSTPRTGNAGNTAKPAWVSGNHGTLIAAFRGPHSGIGGNSGDVHVWLPPQYHDPAYANTRFPVVMLFPGYPGSPTGWFSVLNGGQILGQMAARQQATPFVLVAVNVNQHGENLNCSNIPGGPQMATYVAEDVRTMIEANFRVSDQRTGWGLMGFSDGGLCAGKLLMQYPQYFRSAAQLAGDSTPDGDQVVRAGAAFVERNSTLWLLKHHHPSANQPVSLLASVSDQDTDSLPVAFQLQAAAPDIVSVSEHAHGAHNPAVWRSWLPEMYTWLSRHLDKASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q864</accession>
    <name>C7Q864_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793960.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5372"/>
    <dbReference type="EnsemblBacteria" id="ACU74231">
        <property type="protein sequence ID" value="ACU74231"/>
        <property type="gene ID" value="Caci_5372"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5372"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="TDWFLVM"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="29309" checksum="AEE70E75424E94F5" modified="2009-10-13" version="1" precursor="true">MIADFRRRRAGVAGLAFLVLIAIVALAAPLFISSKDMSAVYAPGTPRQAPSSHFLLGTDAYGRSMVAVTIWGARISLTVGLLATLLAVGIGALVGVAAGHFGGWLDTVLMRVTDWFLVLPVLVLATALAAVLTPGVGTVVVAIGVTAWPTTARVVRAQTLSVESRPYIERAKALGGGHWHVMRRHILPNVMPLMLAQATLTVSAAILTEATLAFLGLSDPTKVSWGTTLQLARAVGAVSAGDWWILLPPGFAIVVVALAFTLVGRALEQVLNPRLQEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q898</accession>
    <name>C7Q898_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsfS</name>
        <name evidence="4" type="ordered locus">Caci_7257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7257"/>
    <dbReference type="EnsemblBacteria" id="ACU76086">
        <property type="protein sequence ID" value="ACU76086"/>
        <property type="gene ID" value="Caci_7257"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7257"/>
    <dbReference type="eggNOG" id="COG0799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092688_2_0_11"/>
    <dbReference type="OMA" id="ARICARI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18681" checksum="C84BF585C66DE704" modified="2009-10-13" version="1">MTATDRARELAIAAAQAASDKVADDIVAYDVSDVFVITDAFVLASANSDRQVRAIVDGIEEKLLEIGAKPARREGEQEGRWVLLDYIDIVVHVQHAEERTYYSLERLWKDCPLIELPDSVTNGRSERPAGAAVLAGENAAADADLDLDTDDDLDADLDLEDDEDDEPAGGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8N9</accession>
    <name>C7Q8N9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1381"/>
    <dbReference type="EnsemblBacteria" id="ACU70304">
        <property type="protein sequence ID" value="ACU70304"/>
        <property type="gene ID" value="Caci_1381"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1381"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_11"/>
    <dbReference type="OMA" id="CAGVDIK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="26447" checksum="0D8BAE43F3939AA6" modified="2009-10-13" version="1">MAVTSTSEPGAAHRGVVTVSVDQPPVNALPVAGWFALADALRAAGQDPETRVVILRAEGRGFNAGVDIKEMQNTAGFDALLGANAGCAAAFAAVYDCPVPVIAEVAGFCVGGGIGLVGNADSIIASDDAYFGLPEVDRGALGAATHLGRLVPQHYLRTMYYTARTVSAQRLLEFGSVWDVVPREKLHARTLELAAEIAAKHPAVIRAAKAALNGIDPVDVKRSYRFEQGFTFEINLAGVADEERDKFVEGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Q5</accession>
    <name>C7Q8Q5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1397"/>
    <dbReference type="EnsemblBacteria" id="ACU70320">
        <property type="protein sequence ID" value="ACU70320"/>
        <property type="gene ID" value="Caci_1397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1397"/>
    <dbReference type="HOGENOM" id="CLU_1666229_0_0_11"/>
    <dbReference type="OrthoDB" id="2224209at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="16915" checksum="E83989A1762AFE60" modified="2009-10-13" version="1">MPGEGGSDSGPTVPSASSGADASSVPHAPSPSSSQPSQSSASSRRGKERIDRLPPDLLEPVVEPRCGIDGWTYQGTELEECFPPQVEAELAQTVHMICTRLATAWNYRRAAQLLESQRAYSQAYAVLEIWSAEGPDPDPTLPKWRARLARAVLANTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T9</accession>
    <name>C7Q8T9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785648.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1431"/>
    <dbReference type="EnsemblBacteria" id="ACU70354">
        <property type="protein sequence ID" value="ACU70354"/>
        <property type="gene ID" value="Caci_1431"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1431"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079334_0_0_11"/>
    <dbReference type="OMA" id="NLRIGWL"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="28939" checksum="53A2E1C942520B5B" modified="2009-10-13" version="1">MSERILITGAAGRIGTALRPLLARPGRVLRLLDIHPVKPGDDDAEIVTASFTDPAALDEACDGVDAVVHLGGKPGEGSWEELAEVNVEGTRQVLEAAVRHGIPRVVLASSIHAAGFWTRDEVGPDGFLPSDTAPRPDTLYGVSKAAVEGLGSLYHSRFGIDVSCLRFGAYRPEPLSIVDLTVWISHEDGARLVQACLSTPPPAGFRVLWGISANARRWFSLAEGAAIGYHPEDDAERFAAGMSGVEDFDWSDPLLHLVGGSFCTLPLGRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q917</accession>
    <name>C7Q917_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3431"/>
    <dbReference type="EnsemblBacteria" id="ACU72337">
        <property type="protein sequence ID" value="ACU72337"/>
        <property type="gene ID" value="Caci_3431"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3431"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_61_1_11"/>
    <dbReference type="OMA" id="ETPIVDC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="945"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1722"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="980"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1813" mass="194542" checksum="8F08A96FAFDE9DB3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J9</accession>
    <name>C7Q9J9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794074.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5486"/>
    <dbReference type="EnsemblBacteria" id="ACU74345">
        <property type="protein sequence ID" value="ACU74345"/>
        <property type="gene ID" value="Caci_5486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5486"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="EAPWERT"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19249" checksum="9C3B295121BAE26C" modified="2009-10-13" version="1">MRKVVVYELTSLDGVAEDPDDFIANWDEAMEANLADVIGSQDAVILGRRSYSAWARFWPKSDIEPFASFINGVAKHVATSTPLDADWQNATVLQDGGLVPAVRALKAQSGGDIGVHASLSVARELLAAGAVDELRLVIAPRIAGGGRRLLDGLPGIALETLETEVSPTGSLLVRYRVLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE4</accession>
    <name>C7QBE4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ThuA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785815.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1600"/>
    <dbReference type="EnsemblBacteria" id="ACU70521">
        <property type="protein sequence ID" value="ACU70521"/>
        <property type="gene ID" value="Caci_1600"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1600"/>
    <dbReference type="eggNOG" id="COG3828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100195_0_0_11"/>
    <dbReference type="OrthoDB" id="1452706at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA" evidence="1">
        <location>
            <begin position="13"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="25059" checksum="C7B298311CEA17F3" modified="2009-10-13" version="1">MTEHVHQGSATKRALVVRGGWDGHVPVPASDRYAAALKDDGYDVTVSDTLDSYLEEDLLAATDLIVQCWTMGQISGEQTTGLLRAVRAGTGFAGWHGGVIDAFRGETRYQLMTGGQFVHHPREFTTYEVHARPERADHPIMAGIAPFTVTTEQYYLHMDPAVEVLAVTDYAEDPDHPELAGVVMPVTWTRQWGAGRVFVTAVGHRVADLEVPEVDEMIRRGMAWATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBF8</accession>
    <name>C7QBF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785829.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1614"/>
    <dbReference type="EnsemblBacteria" id="ACU70535">
        <property type="protein sequence ID" value="ACU70535"/>
        <property type="gene ID" value="Caci_1614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1614"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="QNVMDPL"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="26282" checksum="E99E7EF7FF504DEC" modified="2009-10-13" version="1" precursor="true">MIPKDSEPLQTVVRLSDVRKDFGDYSALDGVGLEIRAGESVAVMGPSGSGKSTLLNLLSGLDRPSAGSVVVCGQDLGKLTEKELALFRRRRIGMVFQFFNLLDDLPALDNVVLAGRLVGLKAGPARRRAMELLDQLGIADRQDVYPASLSGGERQRVAVARALMNRPALLLADEPTGALDSRSGDSVVELLTEVNRQGQTLVVVTHDRRLAARCARRVVDVVDGRIAGEHIAEQVTAHGREQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCE1</accession>
    <name>C7QCE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S16 lon domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794318.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5731"/>
    <dbReference type="EnsemblBacteria" id="ACU74589">
        <property type="protein sequence ID" value="ACU74589"/>
        <property type="gene ID" value="Caci_5731"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5731"/>
    <dbReference type="eggNOG" id="COG2802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048359_1_1_11"/>
    <dbReference type="OMA" id="MLDHTRK"/>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="24509" checksum="751348A3C328ECA8" modified="2009-10-13" version="1">MTTELPLFPLGSVLFPGVVLPLHIFEHRYRQLVRDLSALPEGAPRRFGVLAIKDGHEVGRGNVMALYDVGCTAEIDSIVEYEDGRFDITTTGVHRFRLEAFDDEGPYARGEVELLDEVAGPEADVLAPGLTALFRKYQAALSELRGVQVGSIPELPEDPTVLSYLIGAATVLDTYEKQRLLTTESTVERLRAEAKILRRETGILKNLPSLPAVDLLRRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH4</accession>
    <name>C7QCH4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796162.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7613"/>
    <dbReference type="EnsemblBacteria" id="ACU76437">
        <property type="protein sequence ID" value="ACU76437"/>
        <property type="gene ID" value="Caci_7613"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7613"/>
    <dbReference type="eggNOG" id="COG5517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106738_10_0_11"/>
    <dbReference type="OMA" id="AWTQGTP"/>
    <dbReference type="OrthoDB" id="1736098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15811" checksum="02113FBBC6185DD5" modified="2009-10-13" version="1">MSGYDTQTLADRAEITDLLVNLGRCLDDHDFDGLKDVFTEDVVGTTPAGTREGRQALIDQARRNHESYERLAHQVTSMLVDVDGDAASARAYVTGAFGHADSPEPVRVLVGQYRNKLVRTADGWRISELTVRPVFRVGEPAPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY4</accession>
    <name>C7QCY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785988.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1773"/>
    <dbReference type="EnsemblBacteria" id="ACU70694">
        <property type="protein sequence ID" value="ACU70694"/>
        <property type="gene ID" value="Caci_1773"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1773"/>
    <dbReference type="eggNOG" id="ENOG502ZVAX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085268_0_0_11"/>
    <dbReference type="OMA" id="CEADHGY"/>
    <dbReference type="OrthoDB" id="1956034at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046040">
        <property type="entry name" value="DUF5998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19461">
        <property type="entry name" value="DUF5998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="22674" checksum="3703396065AA5231" modified="2009-10-13" version="1">MPNSQPPSSARPAHGDLIAAIERSGYYPALVAEAVQDAVGSEGVLGHLVHQETTFDADEVRRHVTVLAVTPTRLIAGHTDEYGSDDPMAPVPPGSPESAAGAKAYATTSTETVPLHRISSVVVSRVVEDPANHKPGTPPREVVLTIGWGVVSRLDLEPANCGDPHCDADHGYTGTATADDVMIRVSAEADGADAVAETLSFARALTDVVTEAGARNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD33</accession>
    <name>C7QD33_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1822</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1822"/>
    <dbReference type="EnsemblBacteria" id="ACU70743">
        <property type="protein sequence ID" value="ACU70743"/>
        <property type="gene ID" value="Caci_1822"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1822"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_9_0_11"/>
    <dbReference type="OMA" id="AKCFLLW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="24357" checksum="2160283498E0C03C" modified="2009-10-13" version="1">MLEEIKRVALVHLARDGSALSLRAVARDMGMVSSAIYRYFPSRDELLTALIIDAYNDLSGVVEQADGGVDRRDAYLARWFAVCHAVRRWAIAKPAEYALIYGSPIPGYLAPDDTVEPGSRTVVIMARCIAEAEAAGKLHTAEGVAALPATENSVYAEELRAVAAGIGFAEDSRAVEAAVSAITHVFGAVNFEVFGRLNRVFTERGEWFDRQVREMAVGMGLARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK4</accession>
    <name>C7QDK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794357.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5770"/>
    <dbReference type="EnsemblBacteria" id="ACU74628">
        <property type="protein sequence ID" value="ACU74628"/>
        <property type="gene ID" value="Caci_5770"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5770"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="KWWPSKG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="22075" checksum="0C447C249F9AEB2C" modified="2009-10-13" version="1">MEQTVRAPRDRDEPGRRSREQLRDAVLTAAGELMLEGGLAAATMEAIAARAAVSKRTLYKYWPSRGAVALEGFMRNAASSWSLPDDASATEQLTALVVSAARLFDGTPAGPLMRSLIADAQSQDEIATAIREQWLRPRRAVAADLIRRGVAEGEFRPDIDVEITLDLLFAPVYYRLLLGHEPMDEDFATATVEHAVIGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDT2</accession>
    <name>C7QDT2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5848"/>
    <dbReference type="EnsemblBacteria" id="ACU74706">
        <property type="protein sequence ID" value="ACU74706"/>
        <property type="gene ID" value="Caci_5848"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5848"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1432189_0_0_11"/>
    <dbReference type="OMA" id="RTAVYNH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20357" checksum="C3165B437A840EA1" modified="2009-10-13" version="1">MEHVPKIWSDTLADHRDSVREAIIEAAAAQVAEHGLTGVSMSGIAQAGGIGRATLYKYFPDVASILAAWHDRQIVAHMAELMAAAARAEEADRLEVVLSAYARGSRRDREGHHGAAIAAALHASPQVHQARHALEHYISTLIAEAAERGEVRTDVPAGELAVFCVNALNGAGQLSKPAVERLVAVTLAGLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE35</accession>
    <name>C7QE35_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_7799</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796348.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7799"/>
    <dbReference type="EnsemblBacteria" id="ACU76623">
        <property type="protein sequence ID" value="ACU76623"/>
        <property type="gene ID" value="Caci_7799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7799"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004585_5_6_11"/>
    <dbReference type="OMA" id="YRHFVVD"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="9">
        <location>
            <begin position="18"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="10">
        <location>
            <begin position="299"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="8">
        <location>
            <begin position="664"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="581"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="738"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="738"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="787" mass="85103" checksum="A25667BA851DBB16" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE78</accession>
    <name>C7QE78_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796391.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7842"/>
    <dbReference type="EnsemblBacteria" id="ACU76666">
        <property type="protein sequence ID" value="ACU76666"/>
        <property type="gene ID" value="Caci_7842"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7842"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="185"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="42701" checksum="D38D8F2A44F39737" modified="2009-10-13" version="1">MADIAAYPVPHATRMRPWHWLTLDAVAALLFVLPFGSREVRSPPYQNPWLSLLILGASMVFLARRRYPMTVCLLLTAATVTLGASPPPYDSYGPFAMMFVLYTVAATSSGRLATLASAVVFGAALVILADMHYPVSVLALSGITIGIVPSLIGSLVRQERLYRAETAAANAREIEAEVTSRMAEERLRIARELHDVVAHALSLITVQAGVAVFRRHEAEQMRATLTAIEETGRSAMVDMRQLLGVLRSDPATGSDADADSATDSDTPPSPDRAPIPDLPDLGTLVSQAARAGLRITLREEGERRAVPAAVGLAVYRIVQESLTNILRHARTTSASVLVRFEPDQVAVTVANPPPPDALPPAPAGPPGHGLRGMAERAALFGGTFSAGPAPDGGFTVAARFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE94</accession>
    <name>C7QE94_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1865"/>
    <dbReference type="EnsemblBacteria" id="ACU70785">
        <property type="protein sequence ID" value="ACU70785"/>
        <property type="gene ID" value="Caci_1865"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1865"/>
    <dbReference type="HOGENOM" id="CLU_2421559_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="9309" checksum="BA9590136C166EF9" modified="2009-10-13" version="1">MLDLPLSQGSEAFARLASARLETGVARAGNAPARLRLPAGGAARASFGSTPAVPRITRAFVANATLSPDSRAPSPASNGLTSADIEWFPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC1</accession>
    <name>C7QEC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1892"/>
    <dbReference type="EnsemblBacteria" id="ACU70812">
        <property type="protein sequence ID" value="ACU70812"/>
        <property type="gene ID" value="Caci_1892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1892"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_0_11"/>
    <dbReference type="OMA" id="MYAWHLP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="928"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="400"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="997" mass="104221" checksum="44219F2863FDD47A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI3</accession>
    <name>C7QEI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cof-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786167.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1954"/>
    <dbReference type="EnsemblBacteria" id="ACU70874">
        <property type="protein sequence ID" value="ACU70874"/>
        <property type="gene ID" value="Caci_1954"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1954"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_0_11"/>
    <dbReference type="OMA" id="GAWIQDP"/>
    <dbReference type="OrthoDB" id="1374424at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="29038" checksum="EFBAE9A65F80E031" modified="2009-10-13" version="1">MTLPALPDLIACDLDGTLVRHDGTVSPRTVAAFAALEAAGLPFVFVTGRPPRLMGQIADAFGLHGLAVCSNGAYDYDLRARAVVAEYAIDPATAEKVARGLREAIPGIGLAVEYSDSLAADPLYEPWEWDRDVTVRRLDEADLWRRPAPKLIGRHPSLSADDLLALARPAVGDLVTVYHSNGLRLVEAVAPGVSKADGLARHAARLGVSAEAVMAFGDMPNDLSMFEWAGLAFAVGNAHPSLISVADGVIGSVQEDGVAVFLEALLDRRPDRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEK9</accession>
    <name>C7QEK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792508.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72779">
        <property type="protein sequence ID" value="ACU72779"/>
        <property type="gene ID" value="Caci_3891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3891"/>
    <dbReference type="eggNOG" id="ENOG5032QZ9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147301_0_0_11"/>
    <dbReference type="OMA" id="WWGEAME"/>
    <dbReference type="OrthoDB" id="1570803at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="17234" checksum="FFAD063059E5B959" modified="2009-10-13" version="1">MSDNILSIIPADPDWQPMAEAADAAMAVLRRLVPQFDGFVTTEYRITWHEKVTVIDCGANLERIECPACQNAIGVEWWSDLLEDCVETGFANLAVTVPCCAADVSLNDLHYDWPCGFARFELEAWNPNRDWLPADELAQLAAALGCDVRQVLAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEL0</accession>
    <name>C7QEL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792509.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72780">
        <property type="protein sequence ID" value="ACU72780"/>
        <property type="gene ID" value="Caci_3892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3892"/>
    <dbReference type="HOGENOM" id="CLU_1458811_0_0_11"/>
    <dbReference type="OrthoDB" id="1451192at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20768" checksum="E7D75E405C59ECBF" modified="2009-10-13" version="1">MMIGDPRLFEAEPGDISPVVDQIAGLMPTARCVAGVMQNVVDRVWLRAVEDGRLIREFGAVSESGEVWIDRGERSQVELPFWSRDRWPKLSDEEWETVSVFPFSTESFGDAVIGDLAFGAPLTRLPRHVYELPVTVFDLDAAAVQRTEHEDEIAAIVRRIKIKPLDLNALTNRHDGAHHQGSDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEM7</accession>
    <name>C7QEM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CRISPR-associated protein, Cse1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3909</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the CRISPR-associated helicase Cas3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3909"/>
    <dbReference type="EnsemblBacteria" id="ACU72797">
        <property type="protein sequence ID" value="ACU72797"/>
        <property type="gene ID" value="Caci_3909"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3909"/>
    <dbReference type="eggNOG" id="COG1203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_250011_0_0_11"/>
    <dbReference type="OMA" id="WLAGTHD"/>
    <dbReference type="OrthoDB" id="39968at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035011">
        <property type="entry name" value="Cas3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041372">
        <property type="entry name" value="Cas3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006483">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038257">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013381">
        <property type="entry name" value="CRISPR-assoc_prot_Cse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006474">
        <property type="entry name" value="Helicase_Cas3_CRISPR-ass_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF5">
        <property type="entry name" value="PTHR47959:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18395">
        <property type="entry name" value="Cas3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09481">
        <property type="entry name" value="CRISPR_Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18019">
        <property type="entry name" value="HD_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01587">
        <property type="entry name" value="cas3_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01596">
        <property type="entry name" value="cas3_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02547">
        <property type="entry name" value="casA_cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51643">
        <property type="entry name" value="HD_CAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD Cas3-type" evidence="11">
        <location>
            <begin position="36"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="318"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1520"/>
            <end position="1540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1540" mass="166407" checksum="7B1E43712A6AF7C5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEP0</accession>
    <name>C7QEP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792539.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3924"/>
    <dbReference type="EnsemblBacteria" id="ACU72810">
        <property type="protein sequence ID" value="ACU72810"/>
        <property type="gene ID" value="Caci_3924"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3924"/>
    <dbReference type="eggNOG" id="COG2706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038716_5_1_11"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980905" evidence="1">
        <location>
            <begin position="37"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="42413" checksum="456E2B2A8CA11A28" modified="2009-10-13" version="1" precursor="true">MISYETSRRRVLGVLGVSAVLAAAEPLSGGMTSAQAAEPKSQSAKGSVSAPRGSAQELVYIGTWQGSQIYAARFDTASGELTPVGPVGAANADWSVPHPRLPILYAATMDEGGVVYSFAIDPVTGVLTETGRVATGGAGLGGGGVAYLGIDEPSATLLVSNYEGGLTAAVPISPTGTLGAPASIAQDVGSGPNPRQAGPHAHHVEIAPDGRFALVSDFGADRVFVYRFDRATRILSAGGSGGPYFYATAPGSGPRRVAFHPGHRSAYLLSELTAELETLNWDGATGQLTKRQSLSLVSSGFTGTPSSSDLVVSTDGRFLYAGNRAENSLTAFAVDPRTDLLTEVQRIDCGGVKPWGFSIHADGRWLLVANEASNSVNVFGIDRQSGLLTDTGHSISVPNPDSITFYRSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEU3</accession>
    <name>C7QEU3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792592.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3987"/>
    <dbReference type="EnsemblBacteria" id="ACU72863">
        <property type="protein sequence ID" value="ACU72863"/>
        <property type="gene ID" value="Caci_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3987"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026568_1_0_11"/>
    <dbReference type="OMA" id="AWALHVN"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="45983" checksum="2F9E1422AC85A470" modified="2009-10-13" version="1" precursor="true">MKKKRLAVIGIGVATAGISVLIGQDFHDVAPALWPAAVGEPAEHRAATDAITQAIATAQAALKDTPNDAAQWATLGSAYVEQGRATADPSYYPKADGALHRSLTLSPDQNLQAMVGMGMLTNARHDFATAKDWADKALAFDPDNATAVGVLVDAETQLGDYDAATAAAQRMLDLQPGVASFTRASYDAEQHGHDAIAAEALRRALGDATAPADLAFCHHYLGELSFNAGDPTTALREYRQGLHDDPTYTPALASAAKAEAALGDTAGALRDYAEATARLPLPQYVLEYGELLQSLGRTSDAAAQYTLLDGEQKLFAANGVLDDLTTAQVLADHGDPAQAVEHARTEWGRRHSVLVADALAWALHKAGQDGEALTYARQVAAPGWHNATFAYHRGAIEAALGMTGAARADLGTALSTNPYFSPLQEPQAKALLARLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF02</accession>
    <name>C7QF02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794489.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5902"/>
    <dbReference type="EnsemblBacteria" id="ACU74760">
        <property type="protein sequence ID" value="ACU74760"/>
        <property type="gene ID" value="Caci_5902"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5902"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_11"/>
    <dbReference type="OMA" id="LALQYPK"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05324">
        <property type="entry name" value="carb_red_PTCR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045313">
        <property type="entry name" value="CBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="24977" checksum="F8D154294AFB11C8" modified="2009-10-13" version="1">MSETTIALVTGANKGIGYEIAAGLGAVGFSVGVGARDEGRRDAAVAKLRAAGVDAFGVPLDVTDDASVAAAARLIEERAGRLDVLINNAGIAEGWPDNPTSLDPEVVRRMVDTNVIGVIRVTNAMLPLLRRSAHPRIVNQSSGVSSLTYQTTPGSERGGISGGYTPTKTYLNAVTIQYAKELKDTGILINLACPGYVATDLNGFQGTRTPEQGAAASIRLATLPDDGPSGGLFDDEGVIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL4</accession>
    <name>C7QFL4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpS</name>
        <name evidence="10" type="ordered locus">Caci_7968</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7968"/>
    <dbReference type="EnsemblBacteria" id="ACU76791">
        <property type="protein sequence ID" value="ACU76791"/>
        <property type="gene ID" value="Caci_7968"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7968"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_1_11"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="30"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="37739" checksum="E61E53A4B1965558" modified="2009-10-13" version="1">MGPMAAAPQSSGRKRVFSGIQPTADSFHVGNYLGAIRQWVPLQETHDTVYCVVDLHAITVEQDPKLLRQRTRVAAAQLMAAGIDPGRSTLFVQSHVPEHAQLAWVLTCMTGFGEAGRMTQFKDKSGKQGSANTNVGLFTYPMLMAADVLLYNADEVPVGEDQRQHLELTRDLAQRFNGRYGAYFTVPDPYIIKATGKITDLQEPGAKMSKSASSPAGIIELLDDPKVSAKKIRSAVTDTEREIRYDEQNKAGISNLLSIYSALDGRTIAELETAYEGKGYGDLKKDLAEVFVDFVTPFRERTQAILAEPDKLDAVLAEGAAKARAIATRTLAEVYDRVGFLPAAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFT8</accession>
    <name>C7QFT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786208.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1995"/>
    <dbReference type="EnsemblBacteria" id="ACU70915">
        <property type="protein sequence ID" value="ACU70915"/>
        <property type="gene ID" value="Caci_1995"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1995"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="LEYGQVH"/>
    <dbReference type="OrthoDB" id="293754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="22"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="517" mass="55097" checksum="A5B22BA61BAA18DF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG60</accession>
    <name>C7QG60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4037"/>
    <dbReference type="EnsemblBacteria" id="ACU72905">
        <property type="protein sequence ID" value="ACU72905"/>
        <property type="gene ID" value="Caci_4037"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4037"/>
    <dbReference type="eggNOG" id="COG4961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128792_0_0_11"/>
    <dbReference type="OMA" id="CHANLSD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="16379" checksum="7057A62C336A7426" modified="2009-10-13" version="1">MTRRQPAPRHRAPSRWARFRARPEQGSASLELILLTPIFILFLLMVVAAGRLMDTKIQVDQAVHAAARAASLSMTPGGADTAASSAAAQALSGAGITCSPMTVNTAVTGTAPGGTARVTLSCTVGLGDVSGLGVFPGHETITSSFSSVIDTYRSTPDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG79</accession>
    <name>C7QG79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4059"/>
    <dbReference type="EnsemblBacteria" id="ACU72924">
        <property type="protein sequence ID" value="ACU72924"/>
        <property type="gene ID" value="Caci_4059"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4059"/>
    <dbReference type="HOGENOM" id="CLU_2300726_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="11145" checksum="808B8989336161D1" modified="2009-10-13" version="1">MPRRADPKARTMTEPRFDRAAVASVVRAMEHYDTAWHKELAEYLTADGDVDERRQGEYERAKDDHAWPVLESLPDWIALLKAALGAETAPEAAPETGSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG86</accession>
    <name>C7QG86_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792660.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4066"/>
    <dbReference type="EnsemblBacteria" id="ACU72931">
        <property type="protein sequence ID" value="ACU72931"/>
        <property type="gene ID" value="Caci_4066"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4066"/>
    <dbReference type="HOGENOM" id="CLU_1966587_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="13325" checksum="77FF409D11C02F30" modified="2009-10-13" version="1">MTKTATPAAPSSRDAFTFDAARTACRDILDALAEAGFEPGIEYLAGGCAAISIVLRDGSAVLISDIDASLPLSDAPRARWWALHYPGRWDGYPGDEEPVTVYAADGTAEGDDTAAMLAAVTAYARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ4</accession>
    <name>C7QGJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6017"/>
    <dbReference type="EnsemblBacteria" id="ACU74874">
        <property type="protein sequence ID" value="ACU74874"/>
        <property type="gene ID" value="Caci_6017"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6017"/>
    <dbReference type="HOGENOM" id="CLU_1097075_0_0_11"/>
    <dbReference type="OMA" id="DASHAWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982870" evidence="2">
        <location>
            <begin position="36"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="25430" checksum="B73664453CDD432E" modified="2009-10-13" version="1" precursor="true">MRIRTLLGTTAAAAAALAMVAGCGGSKGSSAKAQAAANAATASTAPTTPAPPTTPTAPASPTASPPSASTAPSTSSARLAPALIQLSDLPEGFRSEGLTQRNLPSLIKGCAGLEVLQQSNIGDQAQAEWTKGALDDYVDEAIIEPKGETAASLVAKAASALNSCGAVKVTEEGLSVTLHATPLSLPKVGDASHAWHTSATFGIASMEMNVVLMQQGNLVVLIAQTRVDGHTNDPLTLSASQAAAKRAADFQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGN0</accession>
    <name>C7QGN0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="10">2.7.1.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">6-phosphofructokinase, pyrophosphate dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">PPi-dependent phosphofructokinase</fullName>
            <shortName evidence="10">PPi-PFK</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pyrophosphate-dependent 6-phosphofructose-1-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pfp</name>
        <name evidence="12" type="ordered locus">Caci_6053</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Non-allosteric.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794639.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6053"/>
    <dbReference type="EnsemblBacteria" id="ACU74910">
        <property type="protein sequence ID" value="ACU74910"/>
        <property type="gene ID" value="Caci_6053"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6053"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_0_0_11"/>
    <dbReference type="OMA" id="TNRDNPF"/>
    <dbReference type="OrthoDB" id="1421302at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02483">
        <property type="entry name" value="PFK_mixed"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="2"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP" evidence="10">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU74910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36415" checksum="830CA89EDDDF80E3" modified="2009-10-13" version="1">MRIGVLTGGGDCPGLNAVIRASVRKGVQFYGFEFVGFRDGWKGPLDRMTKPLDVEAVRGILPRGGTILGSSRTNPLKVEGGVERIKENLAAEGVDALIAIGGEDTLGVATVLGDEYGVNVVGVPKTIDNDLNATDYTFGFDTAVHVATEAIDRLHTTAESHSRALIVEVMGRHAGWIALHSGLAGGANVILIPEVTFDIDEVCGWIESRFARGYAPIVVVAEGATPKDGQMEVSSGELDAFGHVRLGGIGERLADEIERRTKKEARTTVLGHTQRGGTPSPFDRWLATRFGLHAIDAVHDGDFGKMVALRGTDIVRVPLAAATATLKTVPMSLYEEAKVFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGN7</accession>
    <name>C7QGN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Esterase/lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794646.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6060"/>
    <dbReference type="ESTHER" id="catad-c7qgn7">
        <property type="family name" value="CarbLipBact_2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74917">
        <property type="protein sequence ID" value="ACU74917"/>
        <property type="gene ID" value="Caci_6060"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6060"/>
    <dbReference type="eggNOG" id="COG1647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076594_0_1_11"/>
    <dbReference type="OMA" id="DWYAEVD"/>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="4">
        <location>
            <begin position="30"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="28162" checksum="A3028367D27834A1" modified="2009-10-13" version="1">MTAPVLPGAEPFSHDVPAAAEAAEGAGPARIGVLLCHGFTGSPQSLRPWAEHLAEAGFGVRLPRLPGHGTDWHDMQVTTWDDWYAEVDRAFHELQAGYDRVFVMGLSMGGTLTLRLAERHGADVAGIVLVNASVKPDKAVIKLVPVLKLLVPSVAGIGNAINKQGVSELAYSRVPLKALDSFAGGWRTVAADLPKVTQPTLLFRSTADPVVHPSNSAMILSRISATDVTEQVLEKSSHVATLDHDAEQIYAGSVEFVRRVAGLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH12</accession>
    <name>C7QH12_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796587.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8039"/>
    <dbReference type="EnsemblBacteria" id="ACU76862">
        <property type="protein sequence ID" value="ACU76862"/>
        <property type="gene ID" value="Caci_8039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8039"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170329_1_0_11"/>
    <dbReference type="OMA" id="TCPVVHF"/>
    <dbReference type="OrthoDB" id="2031076at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8400" checksum="69BE4FCFFC3888B4" modified="2009-10-13" version="1">MVQAYILVQTEVGKAGAVAQAIAELESGITTAEDVTGPYDVIVRAEAATMDELGRLVIAKIQVIEGITRTLTCPIVHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH68</accession>
    <name>C7QH68_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sucraseferredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8095"/>
    <dbReference type="EnsemblBacteria" id="ACU76918">
        <property type="protein sequence ID" value="ACU76918"/>
        <property type="gene ID" value="Caci_8095"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8095"/>
    <dbReference type="eggNOG" id="COG4759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050357_2_0_11"/>
    <dbReference type="OMA" id="TTLLIYQ"/>
    <dbReference type="OrthoDB" id="1095432at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="24611" checksum="197BB677966F71A7" modified="2009-10-13" version="1">MPKPPKDLPVSVCESALGGCAALCRAAREPLGDTAPPRAKAWLAVEHPGPWPAFGWPQDLPAAAIEVLTAAPAYSVRPQLIRRPDREGRAPAGDRVVFVAGGPPGARWLERRVTGDLGRDIGKLDLAALADGGPPGFGTPLRDRILLVCTHGKRDVCCARYGGPVARELAARGLPVWETTHLGGDQFAANMVCLPDGTYHGRLDRASAAEVALGCLRGEVSAAHFRGRAGVSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHC9</accession>
    <name>C7QHC9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0113"/>
    <dbReference type="EnsemblBacteria" id="ACU69068">
        <property type="protein sequence ID" value="ACU69068"/>
        <property type="gene ID" value="Caci_0113"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0113"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_7_0_11"/>
    <dbReference type="OMA" id="MTGAMVP"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="187"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="42979" checksum="A929B7444598CDBD" modified="2009-10-13" version="1">MSDSENARMRSVDDHLKTVLDTVQLLAPMELPITDVNGLVLAEDVVSAISLPPFDNSSVDGYAVRLADLEGAAEDSPAELRVLGDVAAGSVHEGILEPGTCLRIMTGAMVPHGAEAVVPVEWTDGGTESVRITRVPERDEHIRVLGSDVAAGDVVLKAGTRLGPRQIGLLAAIGQVHAPVHPHPRVVVLSTGSELVEPGTPLGPGQINDGNGPALTAAVNAMGATGIRVGIIGDDPQGVLDAIEDQLIRADMVVTTGGVSVGAYDVVKEVLSTLGTVEFTKVAMQPGMPQGFGTVGEDRIPIFTLPGNPVSAYVSFEIYIRPAIEKMMGIETGPRETVTATCFGAFTSPSGKRQFARGIYDPHGLSVRPVGGHGSHLVGDLALANALIVVPEYVTEVVDGDDVEVIVMEGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHT7</accession>
    <name>C7QHT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71112">
        <property type="protein sequence ID" value="ACU71112"/>
        <property type="gene ID" value="Caci_2193"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2193"/>
    <dbReference type="HOGENOM" id="CLU_2492156_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="9113" checksum="C0D7BA5B14486112" modified="2009-10-13" version="1">MNTFVPAARRPEDSGLTMYENSRGGAGRASAGSMSGTPVFDALVAQFRANFRTVPGEPWSPAPAPRFAEFSVRADRFGLPAGPGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW6</accession>
    <name>C7QHW6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786434.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71141">
        <property type="protein sequence ID" value="ACU71141"/>
        <property type="gene ID" value="Caci_2222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2222"/>
    <dbReference type="HOGENOM" id="CLU_1999792_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="14007" checksum="9DD7CC71B57D6BD2" modified="2009-10-13" version="1">MSKEIVRFNGDRNEVVATLPNVLPGSLTRMAVVKAIATAAENTAYALASARYAVVKVVTETSLQIEFLNERRRVIREDIIPVLAISQSHNDARRAVYNMSLDDDIRQDALADLDRARQRRRDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHZ4</accession>
    <name>C7QHZ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792768.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4175"/>
    <dbReference type="EnsemblBacteria" id="ACU73039">
        <property type="protein sequence ID" value="ACU73039"/>
        <property type="gene ID" value="Caci_4175"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4175"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2178287_0_0_11"/>
    <dbReference type="OMA" id="QWSAKRE"/>
    <dbReference type="OrthoDB" id="1882650at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="12225" checksum="18F3D41E33CD151E" modified="2009-10-13" version="1">MPRGQWSAKRERQYEHVKESVEDRGVPESKAEEIAARTVNKERARHGEAKTSSKLSKEDISSGRRGGLRSHKGSGGRTYDQLYQEARSRGVKGRSKMNKAELEKALGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB6</accession>
    <name>C7QIB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6139"/>
    <dbReference type="EnsemblBacteria" id="ACU74993">
        <property type="protein sequence ID" value="ACU74993"/>
        <property type="gene ID" value="Caci_6139"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6139"/>
    <dbReference type="eggNOG" id="ENOG5033ZTH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_972148_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="27944" checksum="C8FDC98597E0546F" modified="2009-10-13" version="1">MSGAGRANNIGGSDGTGGANDIGGSDGNRDANDIDGSGGNGHSAGGPSGGDGSGDLGDGSDIGGANGIGGSGSNGGVSSIGGFGSNGHGARGLSGGSDIGGFGGSGHGAGGPRGGSGFSGPGGGSGSGSGDPSGANDWPTADLDPVRRMRVLASALPSSAYAELRVDAPFGRVWRYLADMDRSVPELIGFIRRFELAADGSAVATGLLGNRGRFDVELREGWCVMQDRFVVGGFAAVAQDGGGATLLAGCGAVRTAGIRRVVPLLFGERTVLRTLGKVRSRVQTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC5</accession>
    <name>C7QIC5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794731.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6148"/>
    <dbReference type="EnsemblBacteria" id="ACU75002">
        <property type="protein sequence ID" value="ACU75002"/>
        <property type="gene ID" value="Caci_6148"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6148"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="SARMGEM"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="191"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="266"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="52129" checksum="8313BB872E90FD81" modified="2009-10-13" version="1" precursor="true">MSRLRPRTLRGQLTLGLVVLLAVIFAGVGIGTTALLRGFLVTRLDQQLTAAGPRYAQSLEHGLEQNNMDADTRGQTLGTFGARAAGGVITQVGVINGTSLTGDDTGQVRLSPADTRAVLSLPLDGSPHTVRLSALGEYRLRSVPGLDSDVLVTGLPMSQVSETVRELATAEIALFAGAVVVAALGGAAWVRLALRPLDRVATTAERVSTLSLASGEVALEVRVPDADRGDEVGRVGASLNRMLGHVENALARRQSVERRLRDFAADAGHELRTPLAAVRGHAELVLRRGGELPDDARHALTRIEAESRRMGTIVDDLLLLARLDAGRPLASEEVDLTLLVLNAVDDARAADHDESDIGESATRHEWRLDLPTDPVTVPGDPHRLAQAVANFVTNARVHTPAGTLITVGISVDADKVRLAVQDSGPGLAPDLAERAFDRFTRGDPARSRGSGSTGLGLAITRAVAEAHGGGVTVRSKPGRTVFELVLPRTPPSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC8</accession>
    <name>C7QIC8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794734.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6151"/>
    <dbReference type="EnsemblBacteria" id="ACU75005">
        <property type="protein sequence ID" value="ACU75005"/>
        <property type="gene ID" value="Caci_6151"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6151"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127639_0_0_11"/>
    <dbReference type="OMA" id="YGKFGWI"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="13154" checksum="CAE36D00175243E2" modified="2009-10-13" version="1">MERVLGIGGYFLRAADPTALAAWYRDALGLDTDEHGQWQQEAGPSVFAPFAADTGYFGSRAQQTMLNFRVRDLDAMLRQLREKGAAVEADVQEMDGIGRFGWVTDPEGNRIELWQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ0</accession>
    <name>C7QIJ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794796.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6213"/>
    <dbReference type="EnsemblBacteria" id="ACU75067">
        <property type="protein sequence ID" value="ACU75067"/>
        <property type="gene ID" value="Caci_6213"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6213"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_0_0_11"/>
    <dbReference type="OMA" id="HADIREP"/>
    <dbReference type="OrthoDB" id="1139523at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29131" checksum="AFDD862A7644E5C1" modified="2009-10-13" version="1">MTNDAQDRPASQIDSSVPHSARIFNYWLGGKDNYPADRAAGDHFREVFPEIVDLARSGRQFLVRTVRHLTVETGVRQFLDVGTGLPTANNTHEIAQGIAPESRIVYVDNDPLVLAHAQALLVGTPEGATDYIEADLADPEEILSQAAKTLDLSEPVAIVLMGILAHIEDYDRALAIVRRLMDAVPSGSYLVIRDGTDTNDAYREAIGRYNQSGAVPYNLRSPEQIAGYLEGLDLVDPGLVPCPLWRPDPTDIGTPVELAVLGAIGRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS9</accession>
    <name>C7QIS9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796704.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8156"/>
    <dbReference type="EnsemblBacteria" id="ACU76979">
        <property type="protein sequence ID" value="ACU76979"/>
        <property type="gene ID" value="Caci_8156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8156"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_3_1_11"/>
    <dbReference type="OMA" id="TGYAIGD"/>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07576">
        <property type="entry name" value="R-amidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044083">
        <property type="entry name" value="RamA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="275" mass="29662" checksum="95E8890D359FBED4" modified="2009-10-13" version="1">MTLRLACLQAPATDHPDGAPDPVADRRANLAALDDTARRAAESGARLLITPEMYLTGYNLGAEVVAGLAEERFGPAQQEISAIAAKHGIAILYGYPERDGDGVVYNAVQLIGGDGASKANYRKTHLFGDVDRAAFAPGSELVVQADLDGIRVGFLICYDVEFPEPVRAHADAGTQLLLVPTALMRPYEYVPRQIVPARAIESQLFVAYVNRVGVERDFVYAGETRVVAPDGRELAVGGDHEELLLADVDPADLAASRDLNTYLQDRRTDLYGAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIY7</accession>
    <name>C7QIY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8214"/>
    <dbReference type="EnsemblBacteria" id="ACU77037">
        <property type="protein sequence ID" value="ACU77037"/>
        <property type="gene ID" value="Caci_8214"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8214"/>
    <dbReference type="HOGENOM" id="CLU_2895735_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="62" mass="5879" checksum="AB308098B48A2DC1" modified="2009-10-13" version="1">MTGAFSAFLCPAGLRASQRVDIDGAGGVDVPDREPMTGPLGVLLCGGGGAAVVGFGAVVGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ06</accession>
    <name>C7QJ06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784443.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0193"/>
    <dbReference type="EnsemblBacteria" id="ACU69148">
        <property type="protein sequence ID" value="ACU69148"/>
        <property type="gene ID" value="Caci_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0193"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_0_11"/>
    <dbReference type="OMA" id="RMTVFNH"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23506" checksum="61783E49E2CCFAB4" modified="2009-10-13" version="1">METQGLRERKKRQTREEIANVATALFAELGFEKVTIAEVAAAAGVAKMTVTNHFPLKEDLVFDRAEHIVHGLPDAVAARPDGEPVLAAARRYHAQQLAAGDPTLGHRGVDFSRMVESSPALAARERQIHDQREQALAEVLVAQTRPAEELTARVAAAQIAGVYRVLYFTARRFLLDGLQGPEMAETLGACAQRAFTLLEVDLSGFDPRPRLRSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJA9</accession>
    <name>C7QJA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784546.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0298"/>
    <dbReference type="EnsemblBacteria" id="ACU69251">
        <property type="protein sequence ID" value="ACU69251"/>
        <property type="gene ID" value="Caci_0298"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0298"/>
    <dbReference type="HOGENOM" id="CLU_161187_0_1_11"/>
    <dbReference type="OMA" id="QAREMKY"/>
    <dbReference type="OrthoDB" id="2082122at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021426">
        <property type="entry name" value="DUF3073"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11273">
        <property type="entry name" value="DUF3073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="10145" checksum="946EE0BE33724D44" modified="2009-10-13" version="1">MGRGRAKAKQTRVARDLKYRDVRTDLTQLQRELQQDGVHTSNGHSAEAPSQQDDDADDDELYAKYADDDGDDDYDSADDGGAHRSHHRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJE6</accession>
    <name>C7QJE6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2251</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786462.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2251"/>
    <dbReference type="EnsemblBacteria" id="ACU71169">
        <property type="protein sequence ID" value="ACU71169"/>
        <property type="gene ID" value="Caci_2251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2251"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="CEGYRRP"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32240" checksum="37F7027F84587D18" modified="2009-10-13" version="1">MGQPAVEVTGLVKRYGAKTAVDGLDLRVQTGTITAVLGPNGAGKTSTIECCEGYRRPDGGSVRVLGLDPVTQGEQLRPRIGVMLQSGGIYPSVRAAEMLKHTAKLYANPLDTDALIERLGLGSAGRTTFRRLSGGQQQRLSLALAVVGRPELVFLDEPTAGLDVQARHATWELIEQLRRDGVTVVLTTHLLDEAERLADTVAIVDAGKVIAHDTPAALSAANGTADTAIRFTAPPGLDLAGLLAKLPGGLTAVEQPPGGYTVGGDITPNVLAAVTAWCAAKDVMPQGLSVGRRTLEDAFLDLTGRDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK8</accession>
    <name>C7QJK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2313"/>
    <dbReference type="EnsemblBacteria" id="ACU71231">
        <property type="protein sequence ID" value="ACU71231"/>
        <property type="gene ID" value="Caci_2313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2313"/>
    <dbReference type="eggNOG" id="COG1119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="HVLMIRQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="17"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="29780" checksum="80867DF8021C01B2" modified="2009-10-13" version="1">MPNMTTEALSVDPDSVLDLVDVSVVREGRKLLDAVNWTVGEGERWVVLGPNGAGKTTVLNIAAASLFPTAGAVGVLGERLGAVDVFELRPRIGYSSAAVSEKLPRSESVRDVVMTASYGMVGRWREKYDEADAQRADDLLAWWGMAEFGKRTFGTLSEGERKRALIARALMADPELLLLDEPAAGLDLGGREDLVRRLSRLASDPYAPVTVLVTHHVEEIPPGFSHILLVRAGAVVAAGPIETALTSENLTTTFGLALNVERYETPAGLRWYARAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJR3</accession>
    <name>C7QJR3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4287"/>
    <dbReference type="EnsemblBacteria" id="ACU73151">
        <property type="protein sequence ID" value="ACU73151"/>
        <property type="gene ID" value="Caci_4287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4287"/>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055269_1_0_11"/>
    <dbReference type="OMA" id="YQHVHPE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982954" evidence="1">
        <location>
            <begin position="31"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="31826" checksum="580645BDCE3612C5" modified="2009-10-13" version="1" precursor="true">MPMSVSSSLRRALVLAVAACVLAACGHSSGAKSVSGMDMKGMDGANGMNMNMGGSGDDMPGMAEPSGPKIVAAAASDNGLHGAVGGYSYVADASTVAAGSAVPFTFHINGPSGKAVTRFQPYEGQLLVFYVVRTDLGDFRQLTASMRADGTWTVPLPALPAGSYRTYITFAAPDSSAGTPLSYSLSQPLTVPGSAAGVTLPAASDTATADGYALRLTGSPHQGGETGLGVAVTKDGKPVQQFDRLLDGYAHLTAFHSGDAAFARALSTGRSAGGASGAGALTAQILFPEPGAWRLFVQFQTSGVVHTAAFTVEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJR7</accession>
    <name>C7QJR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4291"/>
    <dbReference type="EnsemblBacteria" id="ACU73155">
        <property type="protein sequence ID" value="ACU73155"/>
        <property type="gene ID" value="Caci_4291"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4291"/>
    <dbReference type="eggNOG" id="COG5285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874079_0_0_11"/>
    <dbReference type="OMA" id="STTIRYY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="32238" checksum="A6C93E749963CE72" modified="2009-10-13" version="1">MTAAVAGGSIPGLREANGHLADPPRLRALFDDEGYLFFRGVLNKSAVLATGRQVLRTVVEQGLAQTGMPLTAGEDSRLQDSLNTQRLWEQLVALPDIAAFFATIAGAPVGFIPLARYRIMPPAGTTQIHQDALLNPGFEMTTAWIPLMPINEDLGGLAVAVGSHRQGCMPVDELPPLDGLWRSAAYEPGDVVLMHEALVHTGLPNRSRETLRLSIDVRFQNPGAPAAIVGRIAAVDAASVRIENEASTPTKPTTLSVDASTLLRSSTGQRIPLAVLTTSELTVGRRVIASHRDARAVMIKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJT2</accession>
    <name>C7QJT2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4306"/>
    <dbReference type="EnsemblBacteria" id="ACU73170">
        <property type="protein sequence ID" value="ACU73170"/>
        <property type="gene ID" value="Caci_4306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4306"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_3_11"/>
    <dbReference type="OMA" id="GVGYMIM"/>
    <dbReference type="OrthoDB" id="1694312at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="82"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="29728" checksum="AEB98051DED28869" modified="2009-10-13" version="1">MAEIPFTPTVQLLKRTVPTPLTKVFAGLAVFGKRTVAIVAFLALWEIAPRVGLVDRTFLVPFSEAVKALIELAKDGQLWDNTRASLVRSLSGFLIAIGVGVPLGLLIGWYRPVAEILGPLLELFRNTAALALLPVFILLLGIGETSKIAIVVYACTWPILLNTISGVRSVDPVLIKSARSMALPPHRLFAKVILPAALPTVFTGIRLAGASSILVLVAAEMVGAKAGLGYLVNASQQNFAIPDMYAAIIAIAVVGLVFNHLLVLLERRLTRWRPASGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX4</accession>
    <name>C7QJX4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glu/Leu/Phe/Val dehydrogenase dimerisation region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792941.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4348"/>
    <dbReference type="EnsemblBacteria" id="ACU73212">
        <property type="protein sequence ID" value="ACU73212"/>
        <property type="gene ID" value="Caci_4348"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4348"/>
    <dbReference type="eggNOG" id="COG0334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025763_0_0_11"/>
    <dbReference type="OMA" id="THAMTHA"/>
    <dbReference type="OrthoDB" id="1184827at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="5">
        <location>
            <begin position="146"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="184"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="36266" checksum="A4A94B78A74FD66F" modified="2009-10-13" version="1">MSGFPQWPDHEAVLIRTGARSGLPVVIAMHSSVLGPFAGGCRIWRYPRWQDGLEDALRLSAAMTAKFAAAGLARGGGKSVVAMPEGYELTPAAKRAILLDVGDAIESLDGRYATGPDVGTSPQDMVVIGEQTSHVFCKPAEEGGSGDSSPATAEGSVAALSAIGAWLDGGDSPRLDGLRVAVVGLGSVGARIAALLSEAGAELVLSDIDAAKKAVADRLGARWCEDPHEALTADVDVVVPAALGGVLTEEIVPELRCRAIAGPANNQLAVPQVADALHERGIAWVPDYIASAGGVIHAITVELDKRTEEEALLRVRGIEDTVAGLLQSADDRGVALAVVAEEMVRARLGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY8</accession>
    <name>C7QJY8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792955.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4362"/>
    <dbReference type="EnsemblBacteria" id="ACU73226">
        <property type="protein sequence ID" value="ACU73226"/>
        <property type="gene ID" value="Caci_4362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4362"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="YGTDWSG"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="29528" checksum="167419ED0F0D9BBD" modified="2009-10-13" version="1">MNTERNTKTWFITGASRGFGRIWAEAALSRGDRVAATARRPESLQPLVDVYGDAVLPLVLDVTDRAAAFAAVARAAETFGRLDVVVNNAGYGLFGIVEEVTEEQARAQLDTNLLGPLWVTQAALPYLREQGSGHILQVSSLGGLAGFPTLGLYNASKWGLEGMSEALAQEVGPLGIHVTIVEPGPYGTDWSGGSAVHAEPMAAYEPIREARRAGATTRAPQDPAMTAEVILELVDTEEPPLRLFLGAYPYPVVEAAYRKRLETWEAWRPLATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK31</accession>
    <name>C7QK31_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794834.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6251"/>
    <dbReference type="EnsemblBacteria" id="ACU75105">
        <property type="protein sequence ID" value="ACU75105"/>
        <property type="gene ID" value="Caci_6251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6251"/>
    <dbReference type="eggNOG" id="COG3217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028286_4_0_11"/>
    <dbReference type="OMA" id="PKHCLGV"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOSC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="65"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="25091" checksum="B7D76A7C52316427" modified="2009-10-13" version="1">MYVKELWRYPVKSMQGERLESADVTSNGVAGDRLLHVRDPRGVLTGRTRHALLGVPAATGADGEVRVAGRPWNAPQTAELVRAAAGPGAELVRYAGPERFDVLNLLVATDGAVAELGYDRRRLRPNIVIGGVPGLAERGWPGHALRIGEVLIGMLKLRARCIVTTIDPDTGEQDLDVLRTIRHGYEGTFALDSWTAAPGTIRVGDEVELVDLDPGRARPRPGGWIVGAPYLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKD2</accession>
    <name>C7QKD2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794935.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6352"/>
    <dbReference type="EnsemblBacteria" id="ACU75206">
        <property type="protein sequence ID" value="ACU75206"/>
        <property type="gene ID" value="Caci_6352"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6352"/>
    <dbReference type="eggNOG" id="COG0475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005126_7_0_11"/>
    <dbReference type="OMA" id="PYLWFAK"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="26"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="436" mass="44723" checksum="6D2656567DF5BF0C" modified="2009-10-13" version="1">MPSTSIPAAPLGGHSLLVLVITAGALLVLAMLLGRLAARFGLPAVCGELCAGLILGPSLLGHTVPRFYHWLFPPQAEQVHLLDGVAQFGVLLLVGLTGVDIDLKLVRRRGRVALWVAGFGLVLPLVMGLAAGRLAPSSLLGHGGDRTSFALFAGVAMCVSALPVIAKTLDDMGLLHRDFGQLTVAAGVADDVAGWLLLSVVSALAATGGAHRFPWQAMLWLVVIVLGAVLIARTLAPRVLRRAGRGSTPGPVVATVVAVFLGCAAATQAAGLEASFGAFVGGLVVGTAAEADLRWLAPLRTVVASVLAPLFFATAALRVDLGVLRDPVILGAALVAVAIAAVGKFAGAYLGGMTAKLDRWESLALGAGMNARGVIQLIVASVGLRIGVLNTDSYTIVVLVAVTTSLMAPPILRLAQGRIGGTPAEEERRVRLAAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ6</accession>
    <name>C7PVJ6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Neprosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0400"/>
    <dbReference type="EnsemblBacteria" id="ACU69352">
        <property type="protein sequence ID" value="ACU69352"/>
        <property type="gene ID" value="Caci_0400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0400"/>
    <dbReference type="eggNOG" id="ENOG5033U2S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_996345_0_0_11"/>
    <dbReference type="OMA" id="HLFVYHW"/>
    <dbReference type="OrthoDB" id="1169185at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004314">
        <property type="entry name" value="Neprosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03080">
        <property type="entry name" value="Neprosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982603" description="Neprosin domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Neprosin" evidence="2">
        <location>
            <begin position="90"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="29426" checksum="0A46DC4CF48E82B2" modified="2009-10-13" version="1" precursor="true">MLAKVRVGLVSGLFSMSLLGSTAAAAVPAASAAVLAPRVPTVSAAATDSGPICWYGACYDYVSGHQWTDTTGVSVLMKVEKPVVNPAQTGEHSLQEIALQNTARTSTVEIGWTVDPELNGDNQPHLFVYHWVDGQESCYNACGFVQVSRAIKPGMALHPNEAANFATQNIHGDWWVFFRDEPVGYFPGSLWSGTYQTAQLVSVFGEVAENTADSPSCTQMGDGRFGSSPAASWIRDYRIAGTKDAPNLAVSSTSPNHYDAGAVTPTSFKLGGPGTGACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM4</accession>
    <name>C7PVM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0428"/>
    <dbReference type="EnsemblBacteria" id="ACU69380">
        <property type="protein sequence ID" value="ACU69380"/>
        <property type="gene ID" value="Caci_0428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0428"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062592_5_2_11"/>
    <dbReference type="OMA" id="ITCGGPR"/>
    <dbReference type="OrthoDB" id="1771853at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05829">
        <property type="entry name" value="Sortase_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042001">
        <property type="entry name" value="Sortase_F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980394" evidence="3">
        <location>
            <begin position="26"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="23061" checksum="4BEA5FB177CB0941" modified="2009-10-13" version="1" precursor="true">MRRAWTRGWPAVIAALLLASGCAAGSSTSAGGSGRNAGGTGTNPAAATAGGPAGSQAGGTAGTPAGGTSGTSSAGNSTSAGAIARSDPVRLQIPAIGVDTSVMALGLAADGTVQVPPIEKDSPAGWYNGSPTPGQTGPSVILGHVTVGKYGDGVFLKLAQLKPGAHVVVRLQDGASADFTVDSVRTVAKAQFPTQEVYGNVNRPELRLITCGGERTSDGYLDNVLVFASLTGTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW12</accession>
    <name>C7PW12_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phophohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786697.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2486"/>
    <dbReference type="EnsemblBacteria" id="ACU71404">
        <property type="protein sequence ID" value="ACU71404"/>
        <property type="gene ID" value="Caci_2486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2486"/>
    <dbReference type="eggNOG" id="ENOG5033GCQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1515989_0_0_11"/>
    <dbReference type="OMA" id="FAGTHAS"/>
    <dbReference type="OrthoDB" id="1773064at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="25"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="20322" checksum="AB153441EAEDDAF4" modified="2009-10-13" version="1">MLRPLPPRAMELLEEVAAPPRLIAHLRAVHDVAAELVAWAAKRGLSVDADAVLFGAATHDIGKALHPGELSGPGSEHEHAGRDLLLAKGIAPELAKYAANHSTPSAESTLDELLVSLADTVWKGHRRVDLEDLVVAVLAAESGREVWDEFLELDTLLTDIADGADERLAYQMQFPVTQKPVTARPAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW54</accession>
    <name>C7PW54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793031.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4438"/>
    <dbReference type="EnsemblBacteria" id="ACU73302">
        <property type="protein sequence ID" value="ACU73302"/>
        <property type="gene ID" value="Caci_4438"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4438"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="TGPTCTY"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36356" checksum="F3D4ED058D9E723E" modified="2009-10-13" version="1">MVDIRELARLSGVSPATVSRALNDRAEVSPETRRRILEMAERLGYSPNQPARTLVRRRSDMIGLIWDTGYTNQDRRHPFLLDLFVGIKQTLAESGYHLMVLSTAGAASPGDVGLYLRASQQHSLAGVIMMGVDATHPAITALVDAGTPCVGIDLPLHRNRTTYVTSDNRAGAATAVRHLHGLGHTAIATITGPLTMMPATERLAGYREEMARLNLEPNPHHIVDGDFFLASGYEAARRLTELPHPPTAIFAAGDEMAIGALHALADAGLRVPHDMAVVGFDDIEAAALVRPTLTTVAQDRVALGAGAVEALVDALDADDGTAHAPLQVATRLVVRGSCGAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWI6</accession>
    <name>C7PWI6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyrrolo-quinoline quinone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794995.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6412"/>
    <dbReference type="EnsemblBacteria" id="ACU75266">
        <property type="protein sequence ID" value="ACU75266"/>
        <property type="gene ID" value="Caci_6412"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6412"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_271670_0_0_11"/>
    <dbReference type="OrthoDB" id="147160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981321" evidence="3">
        <location>
            <begin position="31"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="4">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="ASH" evidence="5">
        <location>
            <begin position="547"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="845"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1192" mass="119440" checksum="047032D70FD30E3A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWN5</accession>
    <name>C7PWN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-carboxymethyl-2-hydroxymuconateDelta-isomerase</fullName>
            <ecNumber evidence="2">5.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.3.10" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795044.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6464"/>
    <dbReference type="EnsemblBacteria" id="ACU75315">
        <property type="protein sequence ID" value="ACU75315"/>
        <property type="gene ID" value="Caci_6464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6464"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_3_0_11"/>
    <dbReference type="OMA" id="PTLTKNY"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="67"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="30035" checksum="114B03D8512A3CBC" modified="2009-10-13" version="1">MRLATLRTDEGTRAARREEGFYAVLPHASVGALLSSDDWLQAAAAEETGRVAVAEADFAPVVPHPNKIICLGLNYATHIKEMGRDTPRYPTLFAKYDGALIGAHDPVVLPVVSDTVDWEAELAVVIGRSARHVAESEALEYVAGYTVANDVTVREYQRRTREFLAGKTFEATTPLGPELVTADEFGGREPDLEILCEVDGEVMQRSRTSDLLFGVPDIVAYVSGIITLLPGDVILTGTPGGVGDGRDPKVYLAPGQVLRTVIECLGETRNRCLRESGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY0</accession>
    <name>C7PWY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8414"/>
    <dbReference type="EnsemblBacteria" id="ACU77237">
        <property type="protein sequence ID" value="ACU77237"/>
        <property type="gene ID" value="Caci_8414"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8414"/>
    <dbReference type="eggNOG" id="COG1565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046703_0_0_11"/>
    <dbReference type="OMA" id="CDVTAHV"/>
    <dbReference type="OrthoDB" id="1220759at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="36167" checksum="95AE6FF56672010E" modified="2009-10-13" version="1">MAAVTEWLTWRTAMEQALYGPEGFYRRPGAGPAAHFRTSAHNPVFAEAVGRLLLRVDERLGAPARLDFVDMAAGGGELTAGVVEWLTAAAPEVAARLRAVAVDLRPRPEGLPEAVEWTGSAPSGVVGLLIANEWLDNVVCDVAEVGADGVARIVEVDPDSGDERAGELPDAAQQAWLERWWPLSEGGDSAGARAEIGLDRDAAWRSVVDRLERGVAVAVDYSHTAAGRPRFGTLTGYREGHQVPAVPDGSCDITAHVALDACAAALDSAALDSGAPRDPMVETVLTTQREYLRELGISGARPDLALAASDPLGYLRGLSRASAAAELTDPGGLGGFGWLLAFAGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX25</accession>
    <name>C7PX25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="5">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.16.4" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797007.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8459"/>
    <dbReference type="EnsemblBacteria" id="ACU77282">
        <property type="protein sequence ID" value="ACU77282"/>
        <property type="gene ID" value="Caci_8459"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8459"/>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027070_3_1_11"/>
    <dbReference type="OMA" id="VYGMIVK"/>
    <dbReference type="OrthoDB" id="1499212at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981328" evidence="3">
        <location>
            <begin position="30"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S11" evidence="4">
        <location>
            <begin position="59"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="42132" checksum="7C5FC0102A71AC9C" modified="2009-10-13" version="1" precursor="true">MRWSPVRRSLTVAAACAALVGGGAIAAAAAPPAPSPTPTAPSSAPLGPTVAVPGTPPIPPDVKAGSFVIADEATGAILAERAPHDRLRPASTLKVLTALALMPRLDPAAVHLSVPGDIASLATAEPGASAVGIKPGLSYRVSDLWNAVFLRSGNDAIATLAAMAGGAGPTVDLMRQTAQRLHANDTVVVNADGYDADGQVSSAYDLALMARAGLQDPGFRAYCSLQKAKFPSVNGTTFEIDNENRLLGKYPGMIGVKNGYTSLAHHTFVGAAERNGRTLVVSVFDAGTDIYQQTAKLLDWGFAVPATAAGVDQLVPADPLQKSTAPDETLPPPDAQHAKKRDLLDGYSGSGSGGDLQTSAAAAASPHKSGGSGSSFVGDAFETLLYVLGFLVFAVVALRARVLWKQRKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF4</accession>
    <name>C7PXF4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2489"/>
    <dbReference type="EnsemblBacteria" id="ACU71407">
        <property type="protein sequence ID" value="ACU71407"/>
        <property type="gene ID" value="Caci_2489"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2489"/>
    <dbReference type="eggNOG" id="ENOG50338IN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131922_0_0_11"/>
    <dbReference type="OMA" id="CVWELPP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18865" checksum="87EA2F01C82888B5" modified="2009-10-13" version="1">MVPFYGRLMSYRTPIAWHAGTDVIDGRAVKRYHIARDATPIRPDWEASANALIADMLAPPDETPPAAFTVLFRSGAGLHLNVYSWYWDNVIYGKFATGGVPFLGSPDEDPGNLAPVQPPVLGCVYELGVVVHERSAWIRHVLMTEKPDMDAYLADVLPTGPVGLPDVPSGLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY56</accession>
    <name>C7PY56_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6496"/>
    <dbReference type="EnsemblBacteria" id="ACU75346">
        <property type="protein sequence ID" value="ACU75346"/>
        <property type="gene ID" value="Caci_6496"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6496"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="IEAGPFH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="31487" checksum="5B7F99F91C789551" modified="2009-10-13" version="1">MATMSKAIVFTEYGDPDVLRLLEVPTPEPGPGQVRVRMKAAGVQPADTRSRSGAWQAWMPVRFPARLGNEGAGVIDAVGPGVAGFAVGDEVLGPAAGAYAESVLFQADQIAAKPAIMPWIEAGALSASGQTAHTALEDLGVAAGDTVLIHAAAGGVGHIAVQLARLRGALVVATASPENHEFLRSLGALPVAYGPGLVDRIKEVAPAGVDAALDGAGGEALEVSLEVVGKRDRIGTIADQGGAARLGLRSIGTRRSADRLGELLRLYSEGQLRVAVWKEFPLAQAAAAHRESERGHLRGKIVLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY90</accession>
    <name>C7PY90_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795109.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6532"/>
    <dbReference type="EnsemblBacteria" id="ACU75380">
        <property type="protein sequence ID" value="ACU75380"/>
        <property type="gene ID" value="Caci_6532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6532"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="YNHLLAM"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="33079" checksum="BF211BCF6328E348" modified="2009-10-13" version="1">MIEARGLTKRYGDKLAVDGLSFTVRPGMVTGFLGPNGAGKSTTMRMILGLDVPTSGTVTVNGRSYAEHARPLHEVGALLEARAVHPGRSARNHLLAMAATAGIRRARVEEVIDMVGLAEAADRRVGSFSLGMGQRVGIASALLADPDTLILDEPVNGLDPDGVRWIRILLKGLADEGRTVFLSSHLMSEMALTADHVIVVGRGRLLRDQSMAEFIAEASTNLVKVRSPQAAQLAALLGGAGVTIHNVAEDTLEVAGLTNEQIGTSAASAQITLYELTPAAASLEEAYMALTQDAVTYRSSVGPQVREFESAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYA9</accession>
    <name>C7PYA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6552"/>
    <dbReference type="EnsemblBacteria" id="ACU75399">
        <property type="protein sequence ID" value="ACU75399"/>
        <property type="gene ID" value="Caci_6552"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6552"/>
    <dbReference type="eggNOG" id="ENOG503435H">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_610714_0_0_11"/>
    <dbReference type="OMA" id="WSIANAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980449" evidence="1">
        <location>
            <begin position="28"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="46842" checksum="33BC412E91FA3036" modified="2009-10-13" version="1" precursor="true">MHRKAFTVVWALAFALLGQATLAPAQAAPARHRAEAPGSAADQDIAEWIAQVKKDPGKFDQYLEAGCIESGSSACTLTATQVAAMPSEIKRLTKELNQEVIDDPSLADGAEASAGGIQPRAGISGLSQALSKIGARSGNSFVRKLTSNSATAQQIADVAGNASVANNVAGGLTTATLPAVSKAVIGSVPVFGDVFTIADSIFGKDAAENGPNVEGIVVASVSLIATGVGLAFPPVGAVIAGALAIYSVGKTVLGWFESLLGFLWPQIPPPTPQELFDQGLDVKTTTTPIDGHEYDVVVSKSMKTVTQTILLDSKWTEYNKDSEPLTYIIRPPADGEFPSALNVGSSIYANGHFHTSLQIWQGGKSIPATCTQSISPSCGPDSDMTIGLDRPAVFTITYTVREFLLNSCDRPVCGTENPKLSLRVYDPRTKHDVAIPLSRKVVIVPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYD4</accession>
    <name>C7PYD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795153.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6578"/>
    <dbReference type="EnsemblBacteria" id="ACU75424">
        <property type="protein sequence ID" value="ACU75424"/>
        <property type="gene ID" value="Caci_6578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6578"/>
    <dbReference type="eggNOG" id="ENOG502ZI88">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2141370_0_0_11"/>
    <dbReference type="OMA" id="HVEYWEL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="11941" checksum="1E387A22E3095236" modified="2009-10-13" version="1">MSEDLAQIRAEAVRALSHVEYWELTPARWELLAGMLDALAAAPADDVDAIAVATADLELAGPMRITPIGAGNTRPEAGLTGVVRIPVPPKIRERVNELIHMLRGGGDPGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN0</accession>
    <name>C7PYN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797077.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8529"/>
    <dbReference type="EnsemblBacteria" id="ACU77352">
        <property type="protein sequence ID" value="ACU77352"/>
        <property type="gene ID" value="Caci_8529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8529"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_235019_0_0_11"/>
    <dbReference type="OMA" id="VAFRSEM"/>
    <dbReference type="OrthoDB" id="1602989at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="869"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1395"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1615"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="606"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="933"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1939" mass="206526" checksum="210D75F6BEA085C4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN3</accession>
    <name>C7PYN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8532"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77355">
        <property type="protein sequence ID" value="ACU77355"/>
        <property type="gene ID" value="Caci_8532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8532"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023736_4_0_11"/>
    <dbReference type="OMA" id="RAAMGGW"/>
    <dbReference type="OrthoDB" id="1379602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="48"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="45928" checksum="A38D7347D691C949" modified="2009-10-13" version="1">MSKPSPAQLPTILPGPRPDGVDESATRDDQDRAANAAALRVTRRASICVCMIVKNESAVIERCLASLRGLVDYWVISDTGSTDGTQDLIRAAMADVPGELHEDPWQDFGHNRSLNLEHARGKADYLLLIDADMVLRQEGELPELSADSYMIRHSGDLEYRNKRLVRGDLPWRYVGSTHEYLTTDRPDRELHLDALLVDHFADGGSRADKFERDARLLSADLERDPRNARTVFYLAQTRRDLGEREAAIGLYRRRVALGGWAEEVYFSLLQIGELTADAGAWAAAMETLIEAWEYRPQRLEALYELTSRLRLRGQYQAAYAFANAGIGEPQPDDVLFVRPWVYRWGLLFELSISAYWVDDFIGSVRACDKLLAMPDLPDLHREQTVANREMSRQRLKESRRSYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYW8</accession>
    <name>C7PYW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase, TatD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0587"/>
    <dbReference type="EnsemblBacteria" id="ACU69524">
        <property type="protein sequence ID" value="ACU69524"/>
        <property type="gene ID" value="Caci_0587"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0587"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_4_3_11"/>
    <dbReference type="OMA" id="PNEAPRI"/>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="35043" checksum="72298E862AD2A5E5" modified="2009-10-13" version="1">MADSETGLGGTEPGPADPAASEPGETKRKRKRKSRERDETPPPAPEPLPAPVGDSHTHLDMQEPAAADIIAAADAVNVRRLVQVGVDVPSSRTAVELAAAFERVHAAVALHPNEAPRLVLGDPDGWSGQHRAPGGAAALEEALAEIDKLAADEQVLGIGETGLDYFRTGPEGAQAQQDSFRAHIAIAKRHGKALVIHDRDAHEDVLRILVEEGSPETVVFHCYSGDAAMAKVCAERGYYMSFAGNLTYKANQALQEAFQVAPIDRVLVETDAPFLTPLPYRGRPNAPYLVPYTVRAMAALRGMDSVTGLAELCQALDSNLRDAFQVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZL3</accession>
    <name>C7PZL3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ordered locus">Caci_4667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793257.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4667"/>
    <dbReference type="EnsemblBacteria" id="ACU73528">
        <property type="protein sequence ID" value="ACU73528"/>
        <property type="gene ID" value="Caci_4667"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4667"/>
    <dbReference type="eggNOG" id="COG0274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053595_0_2_11"/>
    <dbReference type="OMA" id="MNACIPP"/>
    <dbReference type="OrthoDB" id="1227369at2"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25206" checksum="87E8D7CCB470F13B" modified="2009-10-13" version="1">MSVASIDVPRWTGPLPTRDEVAKMIDHSLLRPELTPADIQAGLLIAREHNVASVCVRPADVAAVVSGGVLHGTTVAIGTVVAFPHGSSTTATKVFETAELVAQGAEEIDMVIDIGRLRAGDTAFTRDEIAAVVQAAAGRPVKVIFENTYLTQQEKVAGYQAAEAAGAAFVKTSTGFAAGGATAADIALMRQTVSAAVQVKAAGGVRTLDALLELNRLGATRFGATATATILDDLEERRRTSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP4</accession>
    <name>C7PZP4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793288.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4698"/>
    <dbReference type="EnsemblBacteria" id="ACU73559">
        <property type="protein sequence ID" value="ACU73559"/>
        <property type="gene ID" value="Caci_4698"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4698"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_0_1_11"/>
    <dbReference type="OMA" id="CFHFHEV"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27281" checksum="6752F02918ED2D25" modified="2009-10-13" version="1">MHRSDRVTAILDRLAYGGTVDVTTAARELGVSVATIRRDLTLLDDQNLLVRTRGGAVGRDVAYELPVRYRDNHGRAAKQAIARMALRALAPGRHVVAVNGGTTTSEVARLLATRTELTVVTNALNIAGILVNRPKVKLVVTGGVARSNSYEMVGPWAETIVGRFNVDTAFIGIDGISAASGLSTHDEVEAHTNAVIIGRARRVVVVADGSKIGRTHLAHVVGLDAIDQLVTDASADPAELQAIAAQGVAVRIAEPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZR9</accession>
    <name>C7PZR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4723</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4723"/>
    <dbReference type="EnsemblBacteria" id="ACU73584">
        <property type="protein sequence ID" value="ACU73584"/>
        <property type="gene ID" value="Caci_4723"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4723"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_19_3_11"/>
    <dbReference type="OMA" id="LYCVQPM"/>
    <dbReference type="OrthoDB" id="1118058at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="41825" checksum="A77EF9FDB3CE53E7" modified="2009-10-13" version="1">MPVTTVEHQGHLPGTAEYRRVLTALFAAGIATFVLLYDTQALLPDLAHAFHVSPAESTLSVSATTVGLAVALLVFGPLSEALGRTVLIRFSMAASAVLALACAAAPTWDSLIAIRLLAGVALAGLPAVATAYLREEMHPSAQARAAGLYIGGTAIGGMAARLVTAPIAEAAGWRWALLAAAALSTACAVVVAVTLPPSRHFVATRLRGRTVLAMQRRALADPALLALYALGACAVGALVAVFNAVGFRLTAAPFHLGVGLVSLIFLTYSLGTVSSTVSGRLADRLGRRAIAPIGCAVAFGGVLLTLTGSLPVVIVGIAALTVGFFAVHGLASGWVTARSHASGASPSQAAAFYLFSYYVGSSVFGNMGGRAWSADGWPGVVTVAGSLLGIAGVLALALRRIPPLVPPSPAAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS7</accession>
    <name>C7PZS7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793321.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4731"/>
    <dbReference type="EnsemblBacteria" id="ACU73592">
        <property type="protein sequence ID" value="ACU73592"/>
        <property type="gene ID" value="Caci_4731"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4731"/>
    <dbReference type="eggNOG" id="COG2105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125594_1_0_11"/>
    <dbReference type="OMA" id="HREITHH"/>
    <dbReference type="OrthoDB" id="1984556at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14157" checksum="C7F7CB2582FBB661" modified="2009-10-13" version="1">MTLMFLNGGAMRGGPLNHLLKDSPLVGVVRTAPKYRFYSVGDAFPAIEAVDSGGVSVVGELYDVPWEVLERSLLPSEPEELELGVIELEDGGGTLSMVRRRSYAEPHTYRDISHHADWRAYKASLEAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZU3</accession>
    <name>C7PZU3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793337.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4747"/>
    <dbReference type="EnsemblBacteria" id="ACU73608">
        <property type="protein sequence ID" value="ACU73608"/>
        <property type="gene ID" value="Caci_4747"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4747"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_1_0_11"/>
    <dbReference type="OMA" id="TWVRYDG"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14981" checksum="467C28F817CC1FF4" modified="2009-10-13" version="1">MKYLLLKHYRGGPTPAVEFPPMDQWTPEEVDAHVRFMRDFASRLEEAGEFVDMQALSAEGAFVRHGGQGRPPVTDGPFAETKDLIAGWYIIDVDSWDRAVEIAGELSAVPGPGGEPLNEWLEVRPFLGAEAPKTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q035</accession>
    <name>C7Q035_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6682</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795257.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6682"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH74">
        <property type="family name" value="Glycoside Hydrolase Family 74"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75528">
        <property type="protein sequence ID" value="ACU75528"/>
        <property type="gene ID" value="Caci_6682"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6682"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004180_1_0_11"/>
    <dbReference type="OMA" id="YSSWWPD"/>
    <dbReference type="OrthoDB" id="1293876at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982740" evidence="2">
        <location>
            <begin position="37"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="827"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="935" mass="96971" checksum="1BB610FEE9D95E86" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0I9</accession>
    <name>C7Q0I9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797246.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8707"/>
    <dbReference type="EnsemblBacteria" id="ACU77522">
        <property type="protein sequence ID" value="ACU77522"/>
        <property type="gene ID" value="Caci_8707"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8707"/>
    <dbReference type="eggNOG" id="COG3304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120384_2_0_11"/>
    <dbReference type="OMA" id="GVYALWP"/>
    <dbReference type="OrthoDB" id="1806532at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031308">
        <property type="entry name" value="UCP028777"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028777">
        <property type="entry name" value="UCP028777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="68"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14452" checksum="9CB3A62698B3BC22" modified="2009-10-13" version="1" precursor="true">MRFILNIIWLVLCGFWMAVGYVVAGIICCVLIITIPWGLASFRIANYALWPFGRTIVSKPTAGAMSFVGNIIWFIVAGLWLAIGHAVTGVLLCLTIIGIPLGVANFKLIPVSLAPLGKEIVTSREADARFGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0M6</accession>
    <name>C7Q0M6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784949.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0719"/>
    <dbReference type="EnsemblBacteria" id="ACU69654">
        <property type="protein sequence ID" value="ACU69654"/>
        <property type="gene ID" value="Caci_0719"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0719"/>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_2_0_11"/>
    <dbReference type="OMA" id="MPGAMTI"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="21571" checksum="258FBFE1EE633072" modified="2009-10-13" version="1">MTFDLPHPDFRAQLAAEPVIAVVRASSIPDAAALCAALAGGGITCTELTFSTPDVVPHLRAAVAAGHRIGAGTVLTAAQAREAIDAGVSFLVTPGLRPEVAEVAHEAGVPIVLGALTPTEVAQALDLGTAAVKIFPAKAFGPGYFKDLRGPYPGLPLVASGGVNAGNAADFLANGALAVCAGTDVVPPDIVAAGDWPEITRRARAFVTALRRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q132</accession>
    <name>C7Q132_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787000.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2794"/>
    <dbReference type="EnsemblBacteria" id="ACU71707">
        <property type="protein sequence ID" value="ACU71707"/>
        <property type="gene ID" value="Caci_2794"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2794"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138490_0_0_11"/>
    <dbReference type="OMA" id="MSNLMGA"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="14"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="13442" checksum="076653E7B86BB159" modified="2009-10-13" version="1">MSERLPILRIGENLLVSIQVDLDDQTVLNLQDDLAEQVVKHGARGVIIDITAAEIVDSFVGRMLATIASISRLLDAETVVVGMRPAVAITLVELGLSLGDVRTALNLERGLAILSERSSARVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D1</accession>
    <name>C7Q1D1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793389.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4799"/>
    <dbReference type="EnsemblBacteria" id="ACU73660">
        <property type="protein sequence ID" value="ACU73660"/>
        <property type="gene ID" value="Caci_4799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4799"/>
    <dbReference type="eggNOG" id="ENOG50336AB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1184516_0_0_11"/>
    <dbReference type="OMA" id="ASRHKEF"/>
    <dbReference type="OrthoDB" id="1474555at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="219" mass="23543" checksum="44C18D25FE9E1FB4" modified="2009-10-13" version="1">MSEPTAPTAADVRSAADALKAAIDAHLAAVEGRSDESDPAVRTAFLAMAAAAESYDDALYDTYNEVTPFEIPSQYPESAADPDNPEAISVLIRRDYQIEHPGRLLGAARGLAAGAVDPELDISTVSGSLAALFDVFDPDEIHNRSDELGLLPGDGTTWVLASDPEAVADEQWFEDPFSDTDPERIVCRFDVIGDEEDDEYFDTFAEDGAEDEIDGIEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1G3</accession>
    <name>C7Q1G3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4831"/>
    <dbReference type="EnsemblBacteria" id="ACU73692">
        <property type="protein sequence ID" value="ACU73692"/>
        <property type="gene ID" value="Caci_4831"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4831"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="TVHYMSP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="236"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="30730" checksum="AF3578F1A2FF0C6B" modified="2009-10-13" version="1">MLAGRYQLGRTLGVGGSAAVYQATDLVLNRVVAVKLYRALDMDEAQAARAAEEARLLATLNHPSIPPLYDAGIAEGRNYLVTPLISGPTLAQRIRQGPVTPAEAHHLAMALTDALCHVHARGIVHRDVKPGNVLLPPGGGICLVDFGIARALGSQEVTAKSLVVGTAGYLAPERIRGATATTQTDVYAVGLTLLEALLGRRTYEGTALQQVMAAIDRPPTVPVTLGPQWHPLLSALTDSDPHRRPTMSDVFDDLAGWDQSPGQPSPEQQVRAEISSVQPPATQPMRSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Z5</accession>
    <name>C7Q1Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6856"/>
    <dbReference type="EnsemblBacteria" id="ACU75696">
        <property type="protein sequence ID" value="ACU75696"/>
        <property type="gene ID" value="Caci_6856"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6856"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465925_0_0_11"/>
    <dbReference type="OMA" id="ASAAWII"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="595" mass="61715" checksum="FB6C7BDD6FA618C3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q272</accession>
    <name>C7Q272_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase, dUMP-forming</fullName>
            <ecNumber evidence="3">3.5.4.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Bifunctional dCTP deaminase:dUTPase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">DCD-DUT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dcd</name>
        <name evidence="6" type="ordered locus">Caci_8794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + 2 H2O = diphosphate + dUMP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19205"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.5.4.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.30" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8794"/>
    <dbReference type="EnsemblBacteria" id="ACU77609">
        <property type="protein sequence ID" value="ACU77609"/>
        <property type="gene ID" value="Caci_8794"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8794"/>
    <dbReference type="eggNOG" id="COG0717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087476_2_0_11"/>
    <dbReference type="OMA" id="FENHRYP"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033973">
        <property type="term" value="F:dCTP deaminase (dUMP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="70"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="101"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for bifunctional activity" evidence="3">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="23687" checksum="00A3D89D91842068" modified="2009-10-13" version="1">MLLSDKDIRAEIGAGRVVLDPFESAMVQPSSVDVRLDRFFRVFENHRYPYIDPAQEQPELTRLVEPDGDEPFILHPGEFVLASTYEVVTLPEDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPIKLWPGMKIGQLCFFKLSSAAENPYGSAVNQSRYQDQRGPTPSRSYMRFHRTDIAAADKADEAAKAATADEARGGDFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q280</accession>
    <name>C7Q280_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797341.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8804"/>
    <dbReference type="EnsemblBacteria" id="ACU77617">
        <property type="protein sequence ID" value="ACU77617"/>
        <property type="gene ID" value="Caci_8804"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8804"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056519_1_1_11"/>
    <dbReference type="OMA" id="GMQTAVN"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="59"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="32852" checksum="F43E9E34ECD38336" modified="2009-10-13" version="1">MNEIKIGDVTVARVEEMHGPVGMTPEQFFPGWTGEAWQDNRDWLVPHHLGDEDGQVRVAFQTYVLRSEGRTILVDTGVGNDKTRPAVGAWDHLSLGYLENLAAAGVRPEDVDLVVNTHLHVDHIGWNTRLVDGQWVPTFPNATYLMPRVDFEHFDPAKNPGIAGSVNENAFEDSIEPVRAAGRIQLWEDEHRVDGALRLLAAPGHTPGASVLILSSGEDKALFAGDLLHTPLQVAHTEFDSCFCEDPATAQATRRDLLGWAADNTALVLPAHFTGQTALEVARDGDRFAIKNWGPFPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q389</accession>
    <name>C7Q389_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4965"/>
    <dbReference type="EnsemblBacteria" id="ACU73825">
        <property type="protein sequence ID" value="ACU73825"/>
        <property type="gene ID" value="Caci_4965"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4965"/>
    <dbReference type="eggNOG" id="ENOG502ZBMD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049369_0_0_11"/>
    <dbReference type="OMA" id="RERGQIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046050">
        <property type="entry name" value="DUF6008"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19471">
        <property type="entry name" value="DUF6008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="26873" checksum="E60F883FBBB38919" modified="2009-10-13" version="1">MPDMPGMNMSGGHSVPMLDTLGAVGLLVWAVVMWAAVAGLAFADRQGKSMRVYKVSMAVILIGVVGQIGHLTEHVAQAVYWIWHPEAPAWMTPWGTGLARGFGQIDKSRPTLGMEILHLVGNFIFLSGLAAVMVISRRARNTRTRWWGKMGVWMQGIHGLEHLSLTVSVWLGAKQAVGLSTWFGQLTPGPGATTYRVWWHFWANVMGSAIFAMALYHLRRERGQICDTFRDAPVTPPVPVDVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G3</accession>
    <name>C7Q3G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795456.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6890"/>
    <dbReference type="EnsemblBacteria" id="ACU75728">
        <property type="protein sequence ID" value="ACU75728"/>
        <property type="gene ID" value="Caci_6890"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6890"/>
    <dbReference type="HOGENOM" id="CLU_117215_3_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="11836" checksum="480EC64B7AD9A9D3" modified="2009-10-13" version="1">MPLVVFVLMLIIQAGAYYHAQQVAKMAADRAVAVARTEYGTAGFGQVQADRVLKVVGDGSLSDARVNVTRASNEVTVALHANAPHFVPFWPTTISVVSSGPVEAFDEGGHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W6</accession>
    <name>C7Q3W6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="14" type="ordered locus">Caci_8911</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8911"/>
    <dbReference type="EnsemblBacteria" id="ACU77724">
        <property type="protein sequence ID" value="ACU77724"/>
        <property type="gene ID" value="Caci_8911"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8911"/>
    <dbReference type="eggNOG" id="ENOG5032TCV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_2_4_11"/>
    <dbReference type="OMA" id="MWNEKMA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="13">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU77724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14773" checksum="643C89458CBDBCA4" modified="2009-10-13" version="1">MSWVEDWTVVAACRGMDPDELFVQGAAQNRAKTVCSGCPVRTECLADALDNRVEYGVWGGMTERERRALLRRRPEVRSWRQFLESAKEHYERSGAERTGGELGAAAEVDPRFAAATQGAIPRQRNEAGSFGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4G4</accession>
    <name>C7Q4G4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787226.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3024"/>
    <dbReference type="EnsemblBacteria" id="ACU71933">
        <property type="protein sequence ID" value="ACU71933"/>
        <property type="gene ID" value="Caci_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3024"/>
    <dbReference type="eggNOG" id="ENOG5032PKG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1109841_0_0_11"/>
    <dbReference type="OrthoDB" id="2008951at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27405" checksum="7C6DE72BD208FC54" modified="2009-10-13" version="1">MNPNEFITDDETNRLLQEAARRDQRSIGANDIAAWYTDLNVAQVGYDDALAAVSRYYSIHWPKQPPAQRFRLTAPVLIELVGEIRERRHQAANYVYEPVPGETGYQSAARLRAELRAVGDGQPTQNAVRELSSRQKPELEAVLSGIADIRALPDEIRDVLADRRIGVRSIRCPQCNAAPGVRCVTGGGRVMSSPHPSRAETWAVAVAQCPECRAEPESGCHAVGQPYAHGVHPGRLTAARRLIEPVSEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4R9</accession>
    <name>C7Q4R9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3129</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787331.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3129"/>
    <dbReference type="EnsemblBacteria" id="ACU72038">
        <property type="protein sequence ID" value="ACU72038"/>
        <property type="gene ID" value="Caci_3129"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3129"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053650_0_0_11"/>
    <dbReference type="OrthoDB" id="1677723at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="41957" checksum="EC17CCAD450E1499" modified="2009-10-13" version="1">MSGEALTIGEVIGRLAADFPDLTVSKIRYLESGGLISPGRTPAGYRRFTEEDVEKLRWVLAAQRDQYLPLKVIRQHLAADGPRVTAGDADAIVAALTSGSEPAAGTDPATDTAAAAVSGRSERSARWERTPAENGVPGGADAAESPAGAESGRAAAAPDRPRLPPPSTLTPPLPPLPHPRAVTVADPEFFVAARSDVGELHLSRDGLARTAGVSGSFLADLIAYGLVPNAEDYGGDAVIIARAASALTEYGLEPRHLRPLLTGARNTAGLLGTLLPTRRHDGVTGAGRQAAASRAAGRTAEASAAAVKLYGALLRAELAGSGGGAAAAAHGSHSAAAAAATAVSASSAAAAAPTAAETPVAAAVPPIAPIAPIPQISAPSAPVPSVPAPAPPTSADASPTPSVPASRASSRNPGMPGGPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5I0</accession>
    <name>C7Q5I0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797515.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8978"/>
    <dbReference type="EnsemblBacteria" id="ACU77791">
        <property type="protein sequence ID" value="ACU77791"/>
        <property type="gene ID" value="Caci_8978"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8978"/>
    <dbReference type="HOGENOM" id="CLU_1701070_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16069" checksum="02C62BBA710B2539" modified="2009-10-13" version="1">MPVTATLMPATVLDAVHRELIDQLMNTAAPAWFAIADDEETALLAALDSDAARDYLASGCATVDGAWRVFDLLSPLDRSTATPSQAAAVAAVLALAACALNMREHGAAHLGQVQDIDAQHPFVELILTEWDRNADAQSFRTAAAAALGAGTAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T4</accession>
    <name>C7Q5T4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerone kinase</fullName>
            <ecNumber evidence="7">2.7.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.29" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785325.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1105"/>
    <dbReference type="EnsemblBacteria" id="ACU70031">
        <property type="protein sequence ID" value="ACU70031"/>
        <property type="gene ID" value="Caci_1105"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1105"/>
    <dbReference type="eggNOG" id="COG2376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_6_1_11"/>
    <dbReference type="OMA" id="EPKITHY"/>
    <dbReference type="OrthoDB" id="857242at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="6">
        <location>
            <begin position="6"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="5">
        <location>
            <begin position="357"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="572" mass="58504" checksum="5E78401F3A5BFF40" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q639</accession>
    <name>C7Q639_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787338.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3136"/>
    <dbReference type="EnsemblBacteria" id="ACU72045">
        <property type="protein sequence ID" value="ACU72045"/>
        <property type="gene ID" value="Caci_3136"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3136"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_3_1_11"/>
    <dbReference type="OMA" id="HIGGFWI"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11707" checksum="48E888EE600E58B6" modified="2009-10-13" version="1">MQYLVSVLCEGPVTATEEEEAAIDVFNDKLIADGHWVFAGGLGEPVNATVIDHRGGGEPIFTDGPYVESKEFLVGFWVIEAADLDVALKLAAEGSRACNRRVEVRPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q641</accession>
    <name>C7Q641_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_3138</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3138"/>
    <dbReference type="EnsemblBacteria" id="ACU72047">
        <property type="protein sequence ID" value="ACU72047"/>
        <property type="gene ID" value="Caci_3138"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3138"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="AGFPMET"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982552" description="RNA polymerase sigma factor" evidence="7">
        <location>
            <begin position="24"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="8">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="9">
        <location>
            <begin position="167"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="SnoaL-like" evidence="10">
        <location>
            <begin position="243"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU72047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="363" mass="40061" checksum="1D16ADF606EBACE0" modified="2009-10-13" version="1" precursor="true">MTIVTTMTTMTMTTTTTPVTPEADPPTAGSEMRVEDDFVRLADPFRPEILAHCYRMLGSIHDAEDLVQETYLRAWRSYEGFEGRASLRTWLYRIATNACLTALEHRARRPLPAGIGTPHTDPEGDLSAIPPEITWLQPFPDVLLDTGVSAAAGADPASVVAARSGLRLALVAALQYLPPRQRAVLILRDVLGWRSAEVAALLDLTVAAVNSLLKRARARLAEVAPDVEDVAEPTQAEQREILDRWAKAFVEADVDTLMKLLTEDAVYEMPPQPMWFRGAPFLRRLLTFRLGMHGKYRKMIPIRANGQPAFAVYSGDDDRLLAAESVQVLTLRGGKVARVTTFRTPGLVAVAGFPMETELENED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q688</accession>
    <name>C7Q688_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787387.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3186"/>
    <dbReference type="EnsemblBacteria" id="ACU72094">
        <property type="protein sequence ID" value="ACU72094"/>
        <property type="gene ID" value="Caci_3186"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3186"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062592_5_1_11"/>
    <dbReference type="OMA" id="NLAGWYE"/>
    <dbReference type="OrthoDB" id="1771853at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05829">
        <property type="entry name" value="Sortase_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042001">
        <property type="entry name" value="Sortase_F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="24968" checksum="59B6DF09C1CCDCDD" modified="2009-10-13" version="1">MKDADDTRLGISARGVVTASLVSLGLCVGVVLVADSLRTPTPPPQPAASQGFGNAANPAPAAAATAAGPAFDVSKLQPVDMPPMLGPATPTRVRIPAINVNAPLTRLALDSSGRLGAPPEQSRNLAGWYGDGASPGEVGTAVIAGHVDNKRGPAVFYNLGALKKGAEVDVDRSDGMTAVFTVDAVEAYDSRAFPSDKVYGDAARAELRVITCGAGFDKKHYAYMGNVVVFAHLTAAQGKATGTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F8</accession>
    <name>C7Q6F8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5134"/>
    <dbReference type="EnsemblBacteria" id="ACU73993">
        <property type="protein sequence ID" value="ACU73993"/>
        <property type="gene ID" value="Caci_5134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5134"/>
    <dbReference type="HOGENOM" id="CLU_1341247_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982569" evidence="2">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="19915" checksum="079E475359DC749B" modified="2009-10-13" version="1" precursor="true">MRRGQRLRRGAAVLAVAALAGAAAGCGSSGSGSGGHGGTTSSATDGGYHYPGVRARVAVLQLVLDTGQPTDQPVGPDMVVGGTVVYNAGFQTWFGTGGNGTLSPSSHVSLADEAVKAQALIGQVPKLAAAGAAHAVIASELLDAGLIAGSDLPGALDASGKVTAGPAVESWYTAHASQPLAKGSSVSLSDEAARIVAEIEKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F9</accession>
    <name>C7Q6F9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793723.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5135"/>
    <dbReference type="EnsemblBacteria" id="ACU73994">
        <property type="protein sequence ID" value="ACU73994"/>
        <property type="gene ID" value="Caci_5135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5135"/>
    <dbReference type="HOGENOM" id="CLU_364760_0_0_11"/>
    <dbReference type="OrthoDB" id="690169at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="754" mass="77721" checksum="21D04DBA5A0634DB" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S1</accession>
    <name>C7Q6S1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-homologous end joining protein Ku</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ku</name>
        <name evidence="5" type="ordered locus">Caci_5247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Interacts with LigD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic Ku family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793835.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5247"/>
    <dbReference type="EnsemblBacteria" id="ACU74106">
        <property type="protein sequence ID" value="ACU74106"/>
        <property type="gene ID" value="Caci_5247"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5247"/>
    <dbReference type="eggNOG" id="COG1273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048975_1_1_11"/>
    <dbReference type="OMA" id="IRYRKVC"/>
    <dbReference type="OrthoDB" id="1724780at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00789">
        <property type="entry name" value="KU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01875">
        <property type="entry name" value="Prokaryotic_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="Ku70/Ku80_beta-barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009187">
        <property type="entry name" value="Prok_Ku"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41251">
        <property type="entry name" value="PTHR41251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006493">
        <property type="entry name" value="Prok_Ku"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SSF100939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02772">
        <property type="entry name" value="Ku_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="4">
        <location>
            <begin position="52"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="37270" checksum="CBCFCF45EFCACFD7" modified="2009-10-13" version="1">MRAIWSGVISFGMVTVPVKMFGATEEKRVAFHQVHAADGGRVRQKRVCELDGEEVSLSDVAKGYQLPDGDVVVLTSKDFEGLPEAIAKTISVEAFVPEEQIDPIMYSKSYYLAPDKLGVRPYALLRDAMSASGRVAVVRFAMRERESLAALRVREGVLVLETMLWADEIRKPDFDFLDSKVEPKNAELKMAELLIDSLSTDFDPAEYQDSYREALEEVIEAKVAGREVVTPPAPAEGGAQVIDLMAALKASVEAAKKTRGGEGETGKAEKTGKTEKAEKESAKPAAKKTAAAKKSAAAKKTAASASKSAATPSRAAKGARGTAKTADLHKPARKKPATKSTSTRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S8</accession>
    <name>C7Q6S8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795669.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7111"/>
    <dbReference type="EnsemblBacteria" id="ACU75941">
        <property type="protein sequence ID" value="ACU75941"/>
        <property type="gene ID" value="Caci_7111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7111"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_7_3_11"/>
    <dbReference type="OMA" id="GWTDRDE"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="23188" checksum="940912E52BCE55A2" modified="2009-10-13" version="1">MEFQDVIRKRKMVRAFTTEPIAPEVSERLLRAANRAPSAGFSQGYAMLVLESAEDRTAFWEAMDPEGEYEGTALRNAQMIVIPCSNKEIYIDRYARPDKGWTDRDEARWPVPFWHIDTGMLTMLLLLAVVEEDLGALYFGIPPESIGNVRAEFGIPAEFTPIGAVAIGHPDPDRDARQKTSRKTIKRRTVEDITHRGRWHTDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6W4</accession>
    <name>C7Q6W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795705.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7148"/>
    <dbReference type="EnsemblBacteria" id="ACU75977">
        <property type="protein sequence ID" value="ACU75977"/>
        <property type="gene ID" value="Caci_7148"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7148"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_9_0_11"/>
    <dbReference type="OMA" id="DPIRNAY"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980647" evidence="1">
        <location>
            <begin position="32"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="117"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="586" mass="63466" checksum="F3D110E8C3A49DA2" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q757</accession>
    <name>C7Q757_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785439.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1220"/>
    <dbReference type="EnsemblBacteria" id="ACU70145">
        <property type="protein sequence ID" value="ACU70145"/>
        <property type="gene ID" value="Caci_1220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1220"/>
    <dbReference type="HOGENOM" id="CLU_122300_1_0_11"/>
    <dbReference type="OMA" id="FDCSLRW"/>
    <dbReference type="OrthoDB" id="2048416at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019675">
        <property type="entry name" value="DUF2550"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10739">
        <property type="entry name" value="DUF2550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16197" checksum="2702629F244D97DE" modified="2009-10-13" version="1">MLSAVEILAVCFVILCLSVAFIPMRRHLIRRGGGAFDCAVRFGPLPVLGDASGWSFAVGRYRDLTVDLYRVFSYSPRPRTSLARRGFDVVARRDAAGEEGRTLLPGWAVLECSAAGRVVELAMSTESMMAFLTWVEAAPPGWNISRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q779</accession>
    <name>C7Q779_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785461.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1242"/>
    <dbReference type="EnsemblBacteria" id="ACU70167">
        <property type="protein sequence ID" value="ACU70167"/>
        <property type="gene ID" value="Caci_1242"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1242"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="ASHNMAE"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="361" mass="37882" checksum="F413FB954286D7CC" modified="2009-10-13" version="1">MIEVHDLSKRYGDKIAVDHLTFAVEPGQITGFLGPNGAGKSTTMRLILGLDRPQSGTATIGGVPYADLREPLRKVGALLEARAVHTGRSAYNHLLCLAQSQGLPRARVDEALALVGLTEVARKRAGGFSLGMGQRLGIAAAMLGDPQVLILDEPVNGLDPEGVLWIRNLMKSLAAAGKTIFVSSHLMSEMAQTADHLIVIGRGQLIADESVDAFIARSSQRSVLVRTPQPAQLAKELEREAVAASASSAANGNANGNGNGGGSPDADPDGAVTVTTTDDGALIVRGMEAAEIGEKAAAARVVLHELTPQRASLEEAFMELTRGSVEYHVELDQHRDQVPVPAQDTPSVATADRTSESEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7H2</accession>
    <name>C7Q7H2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787458.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3258"/>
    <dbReference type="EnsemblBacteria" id="ACU72165">
        <property type="protein sequence ID" value="ACU72165"/>
        <property type="gene ID" value="Caci_3258"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3258"/>
    <dbReference type="eggNOG" id="ENOG502Z7VP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094210_0_0_11"/>
    <dbReference type="OMA" id="DLIPDMF"/>
    <dbReference type="OrthoDB" id="1342039at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024423">
        <property type="entry name" value="DUF3050"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11251">
        <property type="entry name" value="DUF3050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="29686" checksum="25719EA65DD68D9C" modified="2009-10-13" version="1">MAATRYDWGQRHPGIDQLENRISKAREAVVGHALYARLRDQDAIRTFLEHHVFAVWDFMSLLKSLQRNLTCVEVPWVPTGPTGSRRLINDIVLVEESDELRGGYISHFELYVAGMTEAGADTSSIEAFISLVRAGASVGSALVAAGVPAPAADFVGQTWDIIATAPVHCQAAAFAFGREDLIPDMFQQVVTVNATVGGLDTFVDYLARHIEVDGEQHTPMAMQMLADLCGDDTAKWDECAATVTRALKARARLWDGILAAIGTRETALVGSSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7N2</accession>
    <name>C7Q7N2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3318"/>
    <dbReference type="EnsemblBacteria" id="ACU72225">
        <property type="protein sequence ID" value="ACU72225"/>
        <property type="gene ID" value="Caci_3318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3318"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_2_1_11"/>
    <dbReference type="OMA" id="MPEFGEF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="29378" checksum="90A038C073234AAB" modified="2009-10-13" version="1">MGALNTHFVPALDGVAYGLLLFVAAAGLTLLFGIGGVLNIAHGTLFALGGYLAATVSDGSWSSAFLGLIVATVGGTLGGGVLAASTLPLAERGHLPQALLTFGLALVGGDILSTVYGGDQHPVVIPTSVSGTVHIFGHVYPTYRLLFILVASVLALAGTYVLGRTRAGALLRAAADDRDMVGAMGYAPWRVHAALCGAAGALAGLAGGLGAPIIGPGPDTADKVLMLSMVVIVLGKPGSVAGAFVAAIAVGEIETLGVSISSNWAPYLLFGLMAVGLVARTFRGSSASVGAPAGAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Y6</accession>
    <name>C7Q7Y6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="7" type="ordered locus">Caci_5294</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793882.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5294"/>
    <dbReference type="EnsemblBacteria" id="ACU74153">
        <property type="protein sequence ID" value="ACU74153"/>
        <property type="gene ID" value="Caci_5294"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5294"/>
    <dbReference type="eggNOG" id="COG0326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006684_3_0_11"/>
    <dbReference type="OMA" id="MRRMKEM"/>
    <dbReference type="OrthoDB" id="246194at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HATPase_c" evidence="6">
        <location>
            <begin position="28"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="5">
        <location>
            <begin position="559"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="636" mass="70734" checksum="6743B6E76669A295" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q865</accession>
    <name>C7Q865_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5373"/>
    <dbReference type="EnsemblBacteria" id="ACU74232">
        <property type="protein sequence ID" value="ACU74232"/>
        <property type="gene ID" value="Caci_5373"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5373"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="DVLTMKW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="36087" checksum="F084578B737864A8" modified="2009-10-13" version="1">MTQTVQDGALENEAPGHDVLRLEGLHVSYKTAAGPVPAVRGVDLALPAGGRLGLAGESGCGKSTLAGAVLRLLPKSARVTGRILLDGEDVQTMTWGRLRAVRWAQASIVFQGAMHSLNPVRRVGDQIAEPILLHDKKVSRAAADRRVATLLDQVGLVAARAAAYPHELSGGQRQRVMIAMALACSPRLIVADEPTTALDVMIQAQILRLIGELVSEHGISLLMISHDLAVLAEHCDRLAVMYAGRIVEEGPADRVFADARHPYGRALADAFPRIGDAASRRGPRGLPGDPPDPAHLPEGCTFAPRCPITAEECLTAEPPLIAAGDGRTAACVRMDVLREGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q878</accession>
    <name>C7Q878_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein serine phosphatase with GAF(S) sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7237"/>
    <dbReference type="EnsemblBacteria" id="ACU76066">
        <property type="protein sequence ID" value="ACU76066"/>
        <property type="gene ID" value="Caci_7237"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7237"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_3_11"/>
    <dbReference type="OMA" id="HIATCLY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="230"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="579" mass="61773" checksum="ACF5CEFEA698ABBA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M0</accession>
    <name>C7Q8M0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1362"/>
    <dbReference type="EnsemblBacteria" id="ACU70285">
        <property type="protein sequence ID" value="ACU70285"/>
        <property type="gene ID" value="Caci_1362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1362"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_2_0_11"/>
    <dbReference type="OMA" id="AYSQIYS"/>
    <dbReference type="OrthoDB" id="1629615at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="32"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24565" checksum="360659CBED34DF94" modified="2009-10-13" version="1">MAPQSHDEPAVTGTGTGTGTDDPRLPATSWAVLGMLAFEQELSGYDIKKRADSSLKLFYWSPSFSQIYGELKRLEKHGYVTSRTVMQDEVRGKRVYTISGAGREAVRRWARTAPVEVPVLKHGVLLRVWLGHLTQPERLREIVAEHRDNSERRRAEAAVDVAAAHDETAWAHPEIALKWAERYHAAERDLAERMLADLDALAASGRATAPAAAAISSGPDDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R1</accession>
    <name>C7Q8R1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1403</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785620.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1403"/>
    <dbReference type="EnsemblBacteria" id="ACU70326">
        <property type="protein sequence ID" value="ACU70326"/>
        <property type="gene ID" value="Caci_1403"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1403"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426235_0_0_11"/>
    <dbReference type="OMA" id="FSAREWS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="381"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="525"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="642" mass="68105" checksum="492DEA51A0082256" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I6</accession>
    <name>C7Q9I6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794061.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5473"/>
    <dbReference type="EnsemblBacteria" id="ACU74332">
        <property type="protein sequence ID" value="ACU74332"/>
        <property type="gene ID" value="Caci_5473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5473"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170225_1_0_11"/>
    <dbReference type="OMA" id="TIMTFAD"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="128" mass="14139" checksum="2468870ECBC52403" modified="2009-10-13" version="1">MIIRVWRGWTTPENADAYEALLREEITGESVNGEQTPGMLGIDVMRHDPDAGDGVIGGGGASSAAAEVEFSTIMYFFDWDAVRAFAGEEVFTAVVPDADRALLTRWDERSRHYDLLSRNGQWKTLAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9K5</accession>
    <name>C7Q9K5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA_lig_T4_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794080.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5492"/>
    <dbReference type="EnsemblBacteria" id="ACU74351">
        <property type="protein sequence ID" value="ACU74351"/>
        <property type="gene ID" value="Caci_5492"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5492"/>
    <dbReference type="eggNOG" id="COG4639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_779938_0_0_11"/>
    <dbReference type="OrthoDB" id="979392at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="RNA_ligase_T4-Rnl1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_lig_T4_1" evidence="2">
        <location>
            <begin position="32"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="41557" checksum="9C38BE1FBAF29A77" modified="2009-10-13" version="1">MRLTSTSQVHADHYDQNWEQYEQYWTSVTTRTRGLIVDDTTGRVAAWCLPKFFNHGQHGTFDYAPTLPDEPFEVYDKVDGSLGIVFHYDGAWHAASKGSFISDQAAWAQRYLAKADTSALDPSVTYLAEIVYPENRIVVNYGDRRDLVLLAAFRADGSELALRDAAPAWEGIGSVVRTYDWTDTFGVLAALAEKNQHLDGADATGTDAEGWVIRFASGVRTKTKLTGYVSLHYRLTSVGPRQLWRALAVQLYPEATDVQIAQAVGVQTNEVVGMRRVPGGPLAPLLADVPDEYDAWVRGVCDELTARAAELTASIEAAHSSLAHLAGDRGAYARAAKGFDGFVRAGMFLLLDGRPIAMHVWRAVKPEATEAFRDDDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9K7</accession>
    <name>C7Q9K7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74353">
        <property type="protein sequence ID" value="ACU74353"/>
        <property type="gene ID" value="Caci_5494"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5494"/>
    <dbReference type="HOGENOM" id="CLU_962033_0_0_11"/>
    <dbReference type="OrthoDB" id="856176at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31406" checksum="40EA5732C17D4F55" modified="2009-10-13" version="1">MSSTSKKAPRKPRRVKVCLFYGSRGPLTEEHVFGDWLKKLGYGGSGIREYVDGAAPEIQVGGPFSKTLKILCGPCNNVWTSGMEDAAKPLLINMFSGKQTELDEAAQRDLARWAFKTAAILAHVTRRQEQLPVEHCRAFHRSDEPPPGVFIRIGAASVSTGQHGQQIGESRFLQLPMVMTAGSKRFSIPAYSARFRLFTVVFDVFGSSVSDKVATDLGFAPGDLQVQADVGDDLGRVLVQIWPPKNPTVWWPPVNSLDVVGGIDGLAQVEQFQSIPVILPPPAGVPPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9W4</accession>
    <name>C7Q9W4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4062 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796008.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7458"/>
    <dbReference type="EnsemblBacteria" id="ACU76283">
        <property type="protein sequence ID" value="ACU76283"/>
        <property type="gene ID" value="Caci_7458"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7458"/>
    <dbReference type="eggNOG" id="COG2865">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_739471_0_0_11"/>
    <dbReference type="OMA" id="SATHDEW"/>
    <dbReference type="OrthoDB" id="1046157at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025139">
        <property type="entry name" value="DUF4062"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13271">
        <property type="entry name" value="DUF4062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4062" evidence="1">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="373" mass="40859" checksum="E7D99088199C1410" modified="2009-10-13" version="1">MKIFISSARKGLEKERDSLPGLITALGHTPVHFEDFSAQSTPSREACLAALDSADVCLLLLGPNYGHIFPETGQSATHDEWIHAQVKGIPRLVFRKAGVKLEPKQHEFAQTVEAYATGVFRTTFEDTPDLQIKIAQALRELGSKPSPLEFKRLTQPLAISWTSAENGANSPLSDRGALLETHVAPVDHSGYSAREMESLINSMQNRVRATHYIQNDVALSLSRSKDHAVVRIEDSDRPAWDKPKAGRLLEVRLYQTGQISIRATLPRDRIGSILDRKALTQQIAEMLRLTGALGIIEQGHVAVAVGVLPEMTTSVDTFDPNHPRSSAQFMRFGQSPDMVRIEPDESVNLTALGVGAGEVAGNLSQALFTQLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X0</accession>
    <name>C7Q9X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7464"/>
    <dbReference type="EnsemblBacteria" id="ACU76289">
        <property type="protein sequence ID" value="ACU76289"/>
        <property type="gene ID" value="Caci_7464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7464"/>
    <dbReference type="eggNOG" id="ENOG50309MX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055999_0_0_11"/>
    <dbReference type="OMA" id="YWQQGAR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="33375" checksum="93609861DDC70F48" modified="2009-10-13" version="1">MNIHTGSPTTATALRTGPFAEAFRAAVTARGLSLDSLQRHLAERGVRVGVATLSCWQNGRRRPERPASLRAVSALEDILGLPAGSLLVLLGPPRPRGHGVGLPAGSREYRHILPTWAALTDMLASLGTVADTKLHIAAQHEQVWIDDQGCSPRRETFQILRAHQDDVDRYVAIVDADPGADIARIGVEALENCRLGRVRRDPEAGLLVAELLFDLTLRPHQTHLIRYAVTDHAAVECRDFHRGFRFPAGQYALQVRFAPARLPVACFAYRGAVEEELAMTGHHAVHINVDPVPPGIVGIRWEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA01</accession>
    <name>C7QA01_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldehyde oxidase and xanthine dehydrogenase a/b hammerhead</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1476"/>
    <dbReference type="EnsemblBacteria" id="ACU70399">
        <property type="protein sequence ID" value="ACU70399"/>
        <property type="gene ID" value="Caci_1476"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1476"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_2_3_11"/>
    <dbReference type="OMA" id="LIMTHEN"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="759" mass="78632" checksum="DF45531A23E532A9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA30</accession>
    <name>C7QA30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785722.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70428">
        <property type="protein sequence ID" value="ACU70428"/>
        <property type="gene ID" value="Caci_1507"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1507"/>
    <dbReference type="HOGENOM" id="CLU_805838_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="344" mass="36667" checksum="D8B8B32AE95969B4" modified="2009-10-13" version="1">MTEYELGQEADELEEPAVAGEPVEEYADPYADPQEWISGLIAKLERAEQGIGSGPRDALMARIKLAQAYSELGDTVQAAPLAVANVAQAMALFPSSEGMLRQLREFRDAACEAAGWTAAMMREPDVEELARDEPSELVARPDAGDVAAADDVAAAADSADDYAATADADADAAAEQTPAAPVNADPAEDFAPAQEQLQIQIPVVPAPAADAAEDFAAEDFAPNHETPAPPHQPAEPEPAGAVIHEFVRRSPEPDALQWSAEVQAALTQPAELAIPAAPEPEYAEEVEPDLASGDLAELGDLADLAALEEIIRLRFELREAQRTVERLRHVNRKLREALAFDDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB20</accession>
    <name>C7QB20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7486"/>
    <dbReference type="EnsemblBacteria" id="ACU76311">
        <property type="protein sequence ID" value="ACU76311"/>
        <property type="gene ID" value="Caci_7486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7486"/>
    <dbReference type="HOGENOM" id="CLU_1812303_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14193" checksum="1F1F60217FBD46BB" modified="2009-10-13" version="1">MDTGGTVVKMTGADTPPAGAEVEADVGGAEIGVPLGDGVPEGVPEGVPPPVAGLGELVEVPAAGAECFADVDPHAAARQTTATTHSPARTLEAMLVPAPRIGPPVPSTCLRARVSRPPRTSLHHRVRDGQSAGSGRASLTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB73</accession>
    <name>C7QB73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796089.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7539"/>
    <dbReference type="EnsemblBacteria" id="ACU76364">
        <property type="protein sequence ID" value="ACU76364"/>
        <property type="gene ID" value="Caci_7539"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7539"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="NEEFHAR"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="24116" checksum="10823AA846FB1512" modified="2009-10-13" version="1" precursor="true">MTRTVLVTGGSSGIGRAVAARFVADGADVVVTGRRAQLVETTAQEIGAAGVVCDATDPQAVEALAARFDTLDVLVNAAGGLGSAQPRPGAGALETVLAEWQADLDGNLLSAVLTTTALKPVLAPGGTAIAIGTIGSERRGGSYGAAKAALTAWYAMLSADLGPRGVTANVVSPGYIADTGFFRGAMTDAREQTLIAETHTKRAGAPHDIAETVFFLASPGARQITGQTIHVNGGAFTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB89</accession>
    <name>C7QB89_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796105.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7555"/>
    <dbReference type="EnsemblBacteria" id="ACU76380">
        <property type="protein sequence ID" value="ACU76380"/>
        <property type="gene ID" value="Caci_7555"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7555"/>
    <dbReference type="eggNOG" id="COG1234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031317_3_0_11"/>
    <dbReference type="OMA" id="HIPPWTD"/>
    <dbReference type="OrthoDB" id="1712770at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="18"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27191" checksum="8BEC8C20489DEA33" modified="2009-10-13" version="1">MKLTVIGSSGSFGSPGNPCSSYLVEHGGYRVLLDFGNGALGELQRYGDVYDLQAVILSHLHADHCVDMCGYYVARKYRPGGEPLPLLPVWGPAGTRERIAKAYDTDDAECESVFSFRDVLEGAPEGATGNTFEIGPFTVCVTRVDHPVEAYAIRLEADGHTLVYSGDTGPCAALDNLAKGADLLLAEASFQEPRDNGLLGLHLNGREAGESATAGGVGRLVLTHIPPWTDAELNLAAAKNSYDGPVNLATPGAVFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB94</accession>
    <name>C7QB94_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796110.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7560"/>
    <dbReference type="EnsemblBacteria" id="ACU76385">
        <property type="protein sequence ID" value="ACU76385"/>
        <property type="gene ID" value="Caci_7560"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7560"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_1_0_11"/>
    <dbReference type="OMA" id="CPGIKAR"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9511" checksum="F7734321084E81A6" modified="2009-10-13" version="1">MSINVSIPTILRTYTDGAKRVEAEGTTLAALITDLDARHPGLGDRLLDSGELRRFVNVYKNDEDVRFLGGLSTPLADGDAVTVLPAVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBG0</accession>
    <name>C7QBG0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1616</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785831.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1616"/>
    <dbReference type="EnsemblBacteria" id="ACU70537">
        <property type="protein sequence ID" value="ACU70537"/>
        <property type="gene ID" value="Caci_1616"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1616"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="ALQMVIT"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="155"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="23763" checksum="DCC72A72710CC8B4" modified="2009-10-13" version="1">MPVRVLLADDQPLVRAALAMAIADLPDIEVAGEAGDGLHAVRMTRELCPDVVVMDIRMPGTDGIEATRMITGGAGSARVIVLTTFDDDDNVYNALRAGASGFLVKDMAVSDILAGIRVVAAGDALIAPKVTRRLIAQFASRPRPATAPPTVPAAPPRRIEAITGREREALTFVGRGLSNAEIQVAMGISAATVKTYVTRLLAKLDARDRAQLVIAAYENGLVTPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBI8</accession>
    <name>C7QBI8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ordered locus">Caci_1644</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785859.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1644"/>
    <dbReference type="EnsemblBacteria" id="ACU70565">
        <property type="protein sequence ID" value="ACU70565"/>
        <property type="gene ID" value="Caci_1644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1644"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_11"/>
    <dbReference type="OMA" id="GRRYYEG"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="9"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="44506" checksum="D31EA02E89EF4CB8" modified="2009-10-13" version="1">MHSPAIPELAQEDPQIAGLIEDEARRQYEKIRMIASENYVSAAVLEASGTVLTNKYSEGYAGRRYYEGQQFIDPIETIAIDRAKELFGVAHANVQPYSGSPANLAVYLAFLKPGDTFMGAGLAAGGHLTHGSPVSVTGKWFTPVAYGVSRETGIVDMNEVRDLALKERPKLIFCGGTAIPRTIDFPAFAEIAKEIGAILVSDIAHIAGLVAGGAHPSPVGYADVITTTTHKTLRGPRGAMILTTEEYATPIDKAVFPGLQGGPHNHTTAGIAVALKEAAQPEFRTYAATVVANAKALAAGLTERGWDLVSGGTDNHLILADLTPKGVTGKVAAKALDAAGIELNYNSVPFDPRKPFDPSGIRLGAAAITTRGLKPEQMGQVAQWMDDTVQAAAKGDTDEYARIAGQVRELMAQYPMPGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBZ2</accession>
    <name>C7QBZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72611">
        <property type="protein sequence ID" value="ACU72611"/>
        <property type="gene ID" value="Caci_3709"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3709"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403197_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980820" evidence="1">
        <location>
            <begin position="33"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="52"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="252"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="643" mass="64823" checksum="D0A3873FB5BFBF40" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC60</accession>
    <name>C7QC60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794237.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5649"/>
    <dbReference type="EnsemblBacteria" id="ACU74508">
        <property type="protein sequence ID" value="ACU74508"/>
        <property type="gene ID" value="Caci_5649"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5649"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_5_0_11"/>
    <dbReference type="OMA" id="FEITAMV"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019951">
        <property type="entry name" value="F420_OxRdatse_Rv3520c_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03559">
        <property type="entry name" value="F420_Rv3520c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37574" checksum="01C166CC69BE4953" modified="2009-10-13" version="1">MTADLKLGLQLGYWASKPPEYDWVGLARYAEDLGFDSVWTAESWGSDVFTPLAYLAVSTSRIRLGTGIAQMAARTPTATAMSAITLDHLSGGRVILGLGLSGPQVVEGWYGRPYPKPLARTREYVEVIRKVLRRETVTNDGEFYPLPYQGPDSSGLGKPLRTNLRPLRKDLPIILGAEGPKNVALTAEIADGWLPLYYVPERPEVYADQIAGAKDGFEITAMVHLAFTGAAQDDIEQALWPIKGALAFYVGGMGAKGANFHKNLMVRMGYEAEADHIQELFLDGKRDEAVMAVPTAFADEISLVGPPERIKERLVAWRESPVTTLLVTAREEETLRGLADLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCU7</accession>
    <name>C7QCU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785951.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1736"/>
    <dbReference type="EnsemblBacteria" id="ACU70657">
        <property type="protein sequence ID" value="ACU70657"/>
        <property type="gene ID" value="Caci_1736"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1736"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044189_0_0_11"/>
    <dbReference type="OMA" id="CQVDCVL"/>
    <dbReference type="OrthoDB" id="585089at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045969">
        <property type="entry name" value="DUF5925"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19347">
        <property type="entry name" value="DUF5925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="217"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="45455" checksum="F3642EBE22A29579" modified="2009-10-13" version="1">MTLPRQRPQGPATRPAPDSGGDTPRAPERRTASDPASDPASDPGARLPFRVTIDDSDTPYDVVDALLLTPFTTGLQPHARHARLDALREDATLVPAEGEVLRSVVEDKRESCLTAGPGWTARSVRWSSGGGEVTVVAETPELAAKILEQATDGVAAEEEPEEEKVSVGFWYAAPQRGPYRTVRTITAEPWEAVRQNYSASASAAIDKLMAVRRTEATGRMILLHGAPGTGKTTALRTLAREWREWCQVDYVLDPDALFSSPGYLMEVAMGVEYHGHGEDEENRRRWRLLLLEDCDELIRGEAKATSGQALSRLLNLTDGLLGQGRDVLVAITTNENLASLHPAVIRPGRCLAQIEVGPLPRAEALAWLDREGADPARVAAARLGRGATGSGGPIGGVTLAELIAARDGSEPVASAGDDTGTGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCX9</accession>
    <name>C7QCX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785983.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1768"/>
    <dbReference type="EnsemblBacteria" id="ACU70689">
        <property type="protein sequence ID" value="ACU70689"/>
        <property type="gene ID" value="Caci_1768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1768"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="HCAGRRP"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="34136" checksum="E58FA80D71A89A25" modified="2009-10-13" version="1">MSTLQELEFAAGRPKEIYGEDAKIVCDNLVRIYKTDGIEVQALQGLDLLVRAGELVAIVGASGSGKSTLLNILSGLDTPTAGVARVGGYDLLTMKSRDRLRYRRSTVGFIWQQTARNLLPYLNAADNVALPMGFAGKKRKYARRRSGELLDLLGVGHCAGRRPGQMSGGEQQRVSIAVALANDPEVVFADEPTGELDSATSQQVFDALRTANEELGVSIVVVTHDHEVTDQVQRTVEIRDGRTSSEVLRRGDEGARAEQFAVLDRAGRVQLPKEYVDALRMKDRVRLAKNPDHIGVWPDLAQGSDGAAGSVGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ3</accession>
    <name>C7QCZ3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gly_transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1782"/>
    <dbReference type="EnsemblBacteria" id="ACU70703">
        <property type="protein sequence ID" value="ACU70703"/>
        <property type="gene ID" value="Caci_1782"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1782"/>
    <dbReference type="eggNOG" id="COG2860">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064906_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="64"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18651" checksum="F9F730735768DFAE" modified="2009-10-13" version="1">MIRDALIGATPVAAIADWRYFAVALGATAAVLLVTSRRMSDSKLKSAIEEVRARGVRYDRVAVVADALTLGLFAVSGTLKALDYHLPVFQAALLGTVTATGGGVVRDVLVNEVPMVLQRELYAVPAFVGGLLFALLERHGFVVQGYLAAAGSAAITAAIRLVAVWRDWHAPRPGAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD37</accession>
    <name>C7QD37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786041.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1826"/>
    <dbReference type="EnsemblBacteria" id="ACU70747">
        <property type="protein sequence ID" value="ACU70747"/>
        <property type="gene ID" value="Caci_1826"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1826"/>
    <dbReference type="eggNOG" id="COG2910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_3_0_11"/>
    <dbReference type="OMA" id="DWVVVTP"/>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="20737" checksum="30F00CC62E44851B" modified="2009-10-13" version="1">MVNIIVFGAGGRAGRPAVAEAARRGHTVTAVVRDPAKYPDLAADGVTVVAGDVTDAASVARLAPGHDVAVNTAAAMDEGHFVAAARALVEGLAVAGVGRLVAVGIGGALEVAPGVAAHDSDGIPEEARAFSRNHAAQLPLLRASDLDWVVLAPPLVFLDEGPGTGAYRLGGTQVVPGADTFAYADLALALVDEATAPTRSRELVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD81</accession>
    <name>C7QD81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792403.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3772"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72674">
        <property type="protein sequence ID" value="ACU72674"/>
        <property type="gene ID" value="Caci_3772"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3772"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_11"/>
    <dbReference type="OMA" id="SGYMRDE"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="27"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="224"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="46504" checksum="EC963D5F2409388A" modified="2009-10-13" version="1">MTATTGPTAFRARKLLMLSWEYPPVLVGGLGRHVHALATTLARAGHDVTVATRHAPGAPLEEVVDGVRVVRAPQDPPVIPLDTEHLLAWAVAFNHTLTRTALHAARGQDFELVHAHDWLVAHAAVTVKDHLGIPLVATIHATEAGRHQGWLPGDLNRGIHSIECWLAQESERVLVCSQYMRREVSVLLGVPASKIDAIPNGVDMPRWRAEPKQVGLARAKYADSGPLVGFAGRLVHEKGVQHLLHALPELRRTHPGLRAVICGDGPNRGELEQLTRRLGLEHAVSFGGFLGSRLSATMAATDAMVVPSLYEPFGMVALEAAAAGAPLAVSATGGLAEIVEPGVTGMTFPARDEGALARSVSALLADRPSARRMVVTAKAMVRSRYGWPTVGEQTAAAYAAAVNDAPAVPAGPEELWRSRQHPITIPEGNLLASAGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD84</accession>
    <name>C7QD84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792406.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3775"/>
    <dbReference type="EnsemblBacteria" id="ACU72677">
        <property type="protein sequence ID" value="ACU72677"/>
        <property type="gene ID" value="Caci_3775"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3775"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_3_2_11"/>
    <dbReference type="OMA" id="HAMAPDL"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="18"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="18952" checksum="E2B8BB131F2D2685" modified="2009-10-13" version="1">MTQTPEPGSALPLPANLRVGVVVGNPKPASRTYQAAVHLAERLAGRAPDLTVDLAEYAGLLDWSDAATAAAVAGVTDLDLLVVASPTYKASYTGLLKVFLDRFRADALAGVVAVPLMLGAGPGHAMAPEVFLKPVLAELSAVLPTRALYLLDTSYDDPAAYEPWLAAARRPVLAALRSPVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD87</accession>
    <name>C7QD87_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkanesulfonate monooxygenase</fullName>
            <ecNumber evidence="2">1.14.14.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.14.5" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792409.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3778"/>
    <dbReference type="EnsemblBacteria" id="ACU72680">
        <property type="protein sequence ID" value="ACU72680"/>
        <property type="gene ID" value="Caci_3778"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3778"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_1_0_11"/>
    <dbReference type="OMA" id="EFLWYIP"/>
    <dbReference type="OrthoDB" id="919913at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="38087" checksum="DF89C67A4B94C5B8" modified="2009-10-13" version="1">MELLWYVPNTIEPGHRGDDTADGWGTLDFTLDLATTAEAHGWSGALFGTGWGRPDTFTVATAVAARTTTFKPLAAIRPGYWQPAHFASSAATLSHLSGGRLLVNIVSGQDNLAAYGDAEGDQAQRYARTKEFMRIARRLWTEENVTFDGEYFRVSDSTVVPRLLDGGPRLYFGGASAAAERVSATEADVQLFWGEPLEDIAERIDRLKALSRDLDRDLKPLEFGLRITTLVRDTPEEAWRAAQEKVVKLAERTGVPRTWKSAVGQQRLLDLAGRGDVLDDCLFTTPGRYGGGGAGTTWLVGSADQVAAALRKYADLGISHFILSDTPYKQETARVGDALISRLREPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA7</accession>
    <name>C7QEA7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1878</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the carbamate kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786092.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1878"/>
    <dbReference type="EnsemblBacteria" id="ACU70798">
        <property type="protein sequence ID" value="ACU70798"/>
        <property type="gene ID" value="Caci_1878"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1878"/>
    <dbReference type="eggNOG" id="COG0549">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076278_0_0_11"/>
    <dbReference type="OMA" id="DWCGAQT"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04235">
        <property type="entry name" value="AAK_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="PTHR30409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000723">
        <property type="entry name" value="Carbamate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="32432" checksum="078BCF7BAC224347" modified="2009-10-13" version="1">MRTLIALGGNAMTASDGRARPEDQIAAVGVAMEAVADLVAAGVEVVLTHGNGPQVGNLLVKNELAAHVVPPVPLDWCGAQTQGTLGFVIVSALERALAARGVAKPVAAVVTRTLVDANDRGFTHPTKPIGRYLPKEQAVAMIAHGQTWEDRGERGWRRVVASPEPLEVLDAAAAKTLVEAGYVVVACGGGGIPMVHDLGSAKALRGVEAVIDKDLSAVLLARAVGADHLVIATDVDHMFVHFGTPDVRALDRIDVADLRAHLAAGEFGGGSMAPKAEAACRFVEGGGRRAVVTALGSIREAVLGEAGTVVEGATSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QED9</accession>
    <name>C7QED9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786123.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1910"/>
    <dbReference type="EnsemblBacteria" id="ACU70830">
        <property type="protein sequence ID" value="ACU70830"/>
        <property type="gene ID" value="Caci_1910"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1910"/>
    <dbReference type="HOGENOM" id="CLU_956049_0_0_11"/>
    <dbReference type="OMA" id="IITSKCG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983145" evidence="2">
        <location>
            <begin position="32"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="361" mass="33368" checksum="15EE45EF687DA26D" modified="2009-10-13" version="1" precursor="true">MVLRWRKALIAGGAAVAATGSLYVSVPAARAQTLPAGCVETGARVTCRYAFTGSAQQFMVPPKVTFLIVDLIGAAGGHGCRDSIGIGGDGGKGAQLKGYVILPPNPTGRVVDVYVGGKGGAAETSINGRSCNPVLNGGYNGGGGGGFTAFGGNAGGAGGGASDIRTGRALADRVAVAAGGGGGAGGGFQVYGGEGGNGGASGHPGSTGQASSEGGFPGGHGGQGATPAAPGAGGISSGQCAGQPGFPGILGHGGAGAGVVYPSDGRVVFTESGCGGRGPAPGGLGTGGGGTGGGGGGGVYGGGGGGWGDKPNGGTIFKQAGGGGGGGGSSFIDNPNGSTITSGVATDDGNGRVTITYNIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI2</accession>
    <name>C7QEI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786166.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1953"/>
    <dbReference type="EnsemblBacteria" id="ACU70873">
        <property type="protein sequence ID" value="ACU70873"/>
        <property type="gene ID" value="Caci_1953"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1953"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_1_1_11"/>
    <dbReference type="OMA" id="LARWCYR"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="225"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="735"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="760" mass="79227" checksum="43D932C8E8984011" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFB6</accession>
    <name>C7QFB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796418.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7870"/>
    <dbReference type="EnsemblBacteria" id="ACU76693">
        <property type="protein sequence ID" value="ACU76693"/>
        <property type="gene ID" value="Caci_7870"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7870"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_3_11"/>
    <dbReference type="OMA" id="SHSSGPY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27200" checksum="5512BC6E03696EBA" modified="2009-10-13" version="1">MPSVRVGDIDVYYEIHGEGPPLVFIGGLGVDLTVFAPLTDLLARSFRVLTFDNRGAGRTDKPDAPYSIPMMAGDTVGLMDALGLPRAHMVGISMGGRIAMELAAEHPSRVDRLVLISTAATGTGRLRMSLPARVLGLAKRLHILRGAGETQRQPHFAHQHQLAASAAYDGAERLADIQAPTLILHGKRDRSIKPAAALATRVGIRDSEIDFFRGGHMFSLLAQREAVVARTEDFLQDWRGQRWPTSLPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFN0</accession>
    <name>C7QFN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784264.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0014"/>
    <dbReference type="EnsemblBacteria" id="ACU68969">
        <property type="protein sequence ID" value="ACU68969"/>
        <property type="gene ID" value="Caci_0014"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0014"/>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_23_0_11"/>
    <dbReference type="OMA" id="DNGHPSI"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="9"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17231" checksum="7B4C66940EE1F129" modified="2009-10-13" version="1">MDVWSKEFAGRPECLAEARRFTYAVLGRGDGAHIAALVADELAGNAIRHTASGRPGGEFILRLARFGNRCRVRVDDQGGPTTPEVCAATDFEEAGRGLTIVASLSAQWGVEGDEHARSVWAEITFEEIPGISGPDGPAVDLPPQARARRKVGMTTEDWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ9</accession>
    <name>C7QFQ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein CrgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">crgA</name>
        <name evidence="5" type="ordered locus">Caci_0043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CrgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784293.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0043"/>
    <dbReference type="EnsemblBacteria" id="ACU68998">
        <property type="protein sequence ID" value="ACU68998"/>
        <property type="gene ID" value="Caci_0043"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0043"/>
    <dbReference type="eggNOG" id="ENOG5032ZHR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149126_1_0_11"/>
    <dbReference type="OMA" id="WNIVVGF"/>
    <dbReference type="OrthoDB" id="2085550at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00631">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009619">
        <property type="entry name" value="CrgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06781">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU68998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="84" mass="9440" checksum="F2BC44647AE5BE67" modified="2009-10-13" version="1">MPESKVRKKAAYTPPPDKKQPIKLDTGNRVVLPLMVGCFVLGLLWIVIYYLSNMTYPVSALHGWNMAVGFGLIITGFIASMRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFT4</accession>
    <name>C7QFT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786204.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1991"/>
    <dbReference type="EnsemblBacteria" id="ACU70911">
        <property type="protein sequence ID" value="ACU70911"/>
        <property type="gene ID" value="Caci_1991"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1991"/>
    <dbReference type="HOGENOM" id="CLU_588877_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="464" mass="48550" checksum="8AB0FA3437BCB8B8" modified="2009-10-13" version="1">MSEQKSERLGIADAVERTDWTRYAGQASDVKRRGERRRHRLQAGGVLGTAFAVAGVAAAVQGLGSGVKHQGESPASKPGSSAHVTSPPSFRQRNSPIPTLSGPPSASDYPSFPATLPTKPIFIADPGTVLQSGVIGAGSVSGHPWQISYRVIPSGSAANSEPQVTEVDVSLDGKVVTFGGGEGTHVAWGGYQALDQYLQNSGLVNPMVLAMGSPAANVTSIDLRWKDGTVVQVPIRTVTGTRLASFAWNPANPPDALEQVSAAGVSKITITNDGTATWDHGPLPAPIVPATPPTVTTPTGVPNLSQTPKVTPLSSGILGEGTVSGRKWQLAYEIIPSGSAANDSNEVYCTDSAVDATTEQDGCTSSKPFGTGKVNFSYMFGHQQLPLVITSGTADPGTTSMGLEWADGSKEVNAMQQVEGVPMAAVAFDPNKPPSYLLEFGSYGEYRIPLIGSMRYTWTFNWPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG09</accession>
    <name>C7QG09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2067"/>
    <dbReference type="EnsemblBacteria" id="ACU70986">
        <property type="protein sequence ID" value="ACU70986"/>
        <property type="gene ID" value="Caci_2067"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2067"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_3_11"/>
    <dbReference type="OMA" id="QDNDPGE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="32863" checksum="BD206F138375CDCC" modified="2009-10-13" version="1">MTPMQLDLNLLAALDALLEEGSVAGAADRLHVTAPAMSRSLGRIRRSTGDQILVRTGRTMTPTPYAIAVRAQVHALLQQVQGVLAPSHELDLTTLERTFTLRWHDSLVALGGAALLAAVREQAPGVRLRFIAESSTDSPGLRRGEVDLEANANPPAAADVRAEKVAETAQVVVVRPGHRLAGEPAQPMTAEQYAAADHVAVSRRGNLSGTIDDALARLGLARRVVATAPSEATALEFVRDSDLVVTAPQATTRRASADLGLVVLPLPLDLPPASVYLSWHQRYDTDRAHAWLRELARTALDAPNRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG35</accession>
    <name>C7QG35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786305.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2093"/>
    <dbReference type="EnsemblBacteria" id="ACU71012">
        <property type="protein sequence ID" value="ACU71012"/>
        <property type="gene ID" value="Caci_2093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2093"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_8_1_11"/>
    <dbReference type="OMA" id="FMDTIEG"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="12"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="4">
        <location>
            <begin position="447"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="576" mass="62782" checksum="6116E1B7BAF9BFB7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG47</accession>
    <name>C7QG47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792621.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4024"/>
    <dbReference type="EnsemblBacteria" id="ACU72892">
        <property type="protein sequence ID" value="ACU72892"/>
        <property type="gene ID" value="Caci_4024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4024"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038801_0_0_11"/>
    <dbReference type="OMA" id="ACLELAW"/>
    <dbReference type="OrthoDB" id="453015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="53504" checksum="2C624DE7DF9F5EE4" modified="2009-10-13" version="1">MTVSSSADGWLFSPPVRTAPPDSSDLGDVLKAYRTRHDLSQAELGDLLNCDQSYLSMLERGKRFVRDIGELRRFAAVLGLPEAELGLADGQPAGTLAGGDASTPREVLMDQRAWRSHRRSLNAHRFELSRRAAALYPDAHQIGSTPLLTRRDWLASAPVDLDAITLLWRSDATAPVVTGVEPESAAVRPRSVRGGRHHRYSEAIRLVDRPALFVNRRSFRLLDVAWADGRGRMEFGYTSYFEMVDVCEAVAHELTAADANPMLGQLPFRSLISDPFDLARRPLLPSIDTLTLRRTRDGSATFVLHRREATNVALAGGLIHVMPAGVFQPSTVLPWDQANDFDLWRNMMREFAEEFLGDPEADGDSGEPIDYFDTEPYRTLNQARWERSIRTWCFGLGLDPLTLAGEILAVAVFDADVYDQVFAGIVGRNNEGTVTGTDPARPEAGIAFTNDNITRLLAEERLAPAAAACLYLAWHHRDLLLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGT4</accession>
    <name>C7QGT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6109"/>
    <dbReference type="EnsemblBacteria" id="ACU74964">
        <property type="protein sequence ID" value="ACU74964"/>
        <property type="gene ID" value="Caci_6109"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6109"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_618083_0_0_11"/>
    <dbReference type="OMA" id="WPDRYLL"/>
    <dbReference type="OrthoDB" id="1115604at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="440" mass="47329" checksum="E7A55503C1803680" modified="2009-10-13" version="1">MTSPSPAPEATDALTTAEELLAAEDIAGLVRHLRTQGETLPLLDYVRVLRDAARGMGFDAMVVAGDRVLEAGDDRAEQAVGLYEFGYECVEHGIAFLAIRALREAAEREPGVIQIRTELAAACERSWEHREAMAALRGFEGELPWLARYQLAFNALLAGDVPTAEEEFAALPELEAQEREDLAPLREKVRAMLVRAAEVAVSDGALGPKDLRGWHYALTGGVLLTVSPYGYDAGMTGRWAMVGDSYGAAAEVLRRLGVLLAAKGLTPETVSLLPDRDSRIMGLAAAQYFGLPAVPFAAEREDTLVVAYDLNEAEPEVLAALRNRVPGQILFERATDWTDPPLAAADAVGFLRQAVREPWGAGFRIVDGEVVDTEPDARPVEEIAAELAATEPEADEGDGQTPADPDAVLEAFLAAVEGTWLTARREYVGSPGPVPSSRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGY5</accession>
    <name>C7QGY5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796560.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8012"/>
    <dbReference type="EnsemblBacteria" id="ACU76835">
        <property type="protein sequence ID" value="ACU76835"/>
        <property type="gene ID" value="Caci_8012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8012"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037103_0_0_11"/>
    <dbReference type="OMA" id="ADNGDFY"/>
    <dbReference type="OrthoDB" id="1838610at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="545" mass="58480" checksum="B5A158EAF509FF5D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH22</accession>
    <name>C7QH22_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="14">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Alpha-IPM isomerase</fullName>
            <shortName evidence="14">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">leuC</name>
        <name evidence="17" type="ordered locus">Caci_8049</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796597.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8049"/>
    <dbReference type="EnsemblBacteria" id="ACU76872">
        <property type="protein sequence ID" value="ACU76872"/>
        <property type="gene ID" value="Caci_8049"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8049"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_11"/>
    <dbReference type="OMA" id="CNMSIEM"/>
    <dbReference type="OrthoDB" id="749418at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="12 14 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="16">
        <location>
            <begin position="7"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU76872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="468" mass="49392" checksum="B54EB72C842A8878" modified="2009-10-13" version="1">MPHTLAEKVWADHVVRSADGEPDLLYIDLHLLHEVTSPQAFDGLRQAGRTVRRPDLTIATEDHNTPTLEIDKPIADPVSRLQIETLRKNCADFGVRIHSLGDAQQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLKPFKTMAVTVTGALGEGVTAKDVVLAVIAQIGTGGGQGYVIEYRGEAVEKLSMEGRMTVCNMSIEAGARAGMIAPDETTFAYLKGRAHAPSGADWDAAVEYWKTLRTEDGATFDAEVVIDGDALTPYVTWGTNPGQGLPLSASVPDPDKDFGAEVDKVAARKALEYMGLQAGTPLREIKVDTVFLGSCTNGRLEDLRAAAAVIKGRQVADGVRMLVVPGSARVRLEAEAEGLHEVFTAAGAEWRFAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPSDLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG8</accession>
    <name>C7QHG8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0152"/>
    <dbReference type="EnsemblBacteria" id="ACU69107">
        <property type="protein sequence ID" value="ACU69107"/>
        <property type="gene ID" value="Caci_0152"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0152"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_1_11"/>
    <dbReference type="OMA" id="VDPRSYM"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="13"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="48902" checksum="2DF87626CA37A1D6" modified="2009-10-13" version="1">MGKASGNGKAIPRILIVGGGYVGMYTAHRILKKLGKDEALVTVVDPRSYMTYQPFLPEAAAGSLSPRHVVVPLRSVLKRAEVLTARVTDIDQNRKVATIEPIAGEPYELEFDQLVIAVGSIARTLPIPGLAENGIGFKQIEEAIALRNHVLGQMDIAATTKDEKIRRRALTFVFIGGGFAGIEAIAELEDMARDACKIYPNIRPEDMRWVMVEGSGRILPEVRPALGEYTVHELEKRGIQVKLNTFLESCVNRRVQLSDGTKMVASTIVWTAGVKPNPVVQRFGVPLGERGHVKAGATLQVEGFADVWSAGDGAQVPDLANPGKWCSPSAQHAVRQAKQLADNVVAAVRGFEPREYKHKHVGSVASLGLHKGVADVYNIRLRGWPAWFMHRTYHMSRVPTFNRKIRVIADWTLALFFRREAVGLGSIERPRDEFAEAAGEQRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG9</accession>
    <name>C7QHG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ppx/GppA phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784403.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0153"/>
    <dbReference type="EnsemblBacteria" id="ACU69108">
        <property type="protein sequence ID" value="ACU69108"/>
        <property type="gene ID" value="Caci_0153"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0153"/>
    <dbReference type="eggNOG" id="COG0248">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025908_1_2_11"/>
    <dbReference type="OMA" id="IGCVRMT"/>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="34033" checksum="B62E56AEE8490AB9" modified="2009-10-13" version="1">MTKRVAAIDCGTNSIRLLIADVHPRTGRTEDVVREMRIVRLGEGVDATGRLAPAALERTFAACLEYQDLIERHSGGTPIPLRFVATSATRDAENRREFVEGVKGILGVEPYVATGDEEARFSFTGATSELPHDRHQAPYLVIDIGGGSTEFVLGDAERGVIAARSVDMGCVRMYERHLKTAGVATEAQVKAARADIEKLIDRAAEAVPLDEARTLVGLAGTVTTLGAVALDLDEYDSERIHLSHIPLGRVRDITTRLLGLTPDERKAIPVIHPGRADVIGAGALVLLAIMERVAPSLAAPEVVVSERDILDGIAASIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHL0</accession>
    <name>C7QHL0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2116"/>
    <dbReference type="EnsemblBacteria" id="ACU71035">
        <property type="protein sequence ID" value="ACU71035"/>
        <property type="gene ID" value="Caci_2116"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2116"/>
    <dbReference type="HOGENOM" id="CLU_1537313_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="3">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="17864" checksum="230FCD2A97ACD7CA" modified="2009-10-13" version="1">MSDTAAGGQGSGTEGFAPPGDGYAPPGYAPPGYAPPRYAQQDAVPPGYASPTQDMVPVQPTFPTSFSAAPQYFGPQPPQLYPGGYYGPPMLRPQTSGMAVAGMVTGICSMLLFWAPLLAPVLAIMGLVFSGMGISQSSRQGWTGTGMAIAGLVCSAITAVIWVLLVIFVVALFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIA3</accession>
    <name>C7QIA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobaltochelatase, CobN subunit</fullName>
            <ecNumber evidence="1">6.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.6.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794709.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6126"/>
    <dbReference type="EnsemblBacteria" id="ACU74980">
        <property type="protein sequence ID" value="ACU74980"/>
        <property type="gene ID" value="Caci_6126"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6126"/>
    <dbReference type="eggNOG" id="COG1429">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002017_1_0_11"/>
    <dbReference type="OMA" id="YQFQGGL"/>
    <dbReference type="OrthoDB" id="8025at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051116">
        <property type="term" value="F:cobaltochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10150">
        <property type="entry name" value="CobN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011953">
        <property type="entry name" value="Cobalto_CobN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003672">
        <property type="entry name" value="CobN/Mg_chltase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44119">
        <property type="entry name" value="PTHR44119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02514">
        <property type="entry name" value="CobN-Mg_chel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02257">
        <property type="entry name" value="cobalto_cobN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1238" mass="132616" checksum="9C2022621DB2B332" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG5</accession>
    <name>C7QIG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794771.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6188"/>
    <dbReference type="EnsemblBacteria" id="ACU75042">
        <property type="protein sequence ID" value="ACU75042"/>
        <property type="gene ID" value="Caci_6188"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6188"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_13_1_11"/>
    <dbReference type="OMA" id="VDCYAGG"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20919" checksum="5ED1AE906F490636" modified="2009-10-13" version="1">MRIRVGGRDDVPVILAFGDEAVAWMNARGNTQQWGTAAWTSLDKRREAFLERADGGGMRVLEDEDGTALGVMVISEQRQPYVPEAEERELYVNFLIISRAHAGRGIGRLLIERAKQEAAERGIDLLRVDCWAGEDGNLVKVYERYGFVRVKEFTVAEAGDWPGMLLAMRLSELPEGERPEGERPGAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV5</accession>
    <name>C7QIV5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796730.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8182"/>
    <dbReference type="EnsemblBacteria" id="ACU77005">
        <property type="protein sequence ID" value="ACU77005"/>
        <property type="gene ID" value="Caci_8182"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8182"/>
    <dbReference type="eggNOG" id="COG5305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029834_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018674">
        <property type="entry name" value="DUF2142_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09913">
        <property type="entry name" value="DUF2142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="479"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="611" mass="63673" checksum="BF7F736C94C34E42" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG8</accession>
    <name>C7QJG8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2273"/>
    <dbReference type="EnsemblBacteria" id="ACU71191">
        <property type="protein sequence ID" value="ACU71191"/>
        <property type="gene ID" value="Caci_2273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2273"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_0_11"/>
    <dbReference type="OMA" id="QEAFTWW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="32991" checksum="FB583357F2C97726" modified="2009-10-13" version="1">MGTPPSSVSAVNGGHLSAPLQAGADTSIVLSCAGATSYPRVVSLFGTVRTDSGERMSWEDTARQAAEAGIDVLLEGEAATLTLNRPDKRNSQTPEFWAALAAIGAALPGTVRVVVLRAEGKSFSAGLDRSMFENFATFAALSDDEVDRTIEGYQQAFTWWRRTDLITVAAVQGHAIGAGFQLALACDIRIAADDVLFCMKEPALGLVPDLAGTQPLVDAVGYSRALEIVATARYVDAEEALRIGLANHVVPREELHAAAAKLAADLLAAPRGAVTESKALLRAAAGRPYDEQRAAERAAQTRRFRDLAGTGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJH3</accession>
    <name>C7QJH3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2278"/>
    <dbReference type="EnsemblBacteria" id="ACU71196">
        <property type="protein sequence ID" value="ACU71196"/>
        <property type="gene ID" value="Caci_2278"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2278"/>
    <dbReference type="eggNOG" id="COG3293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529901_0_0_11"/>
    <dbReference type="OMA" id="GSGQTCW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="19948" checksum="EC2F11F26942365E" modified="2009-10-13" version="1">MLLGVPAPRRDPAAAPAAGSTLTRLRRTGHQDPVVTDRAWERISTLLPERPRRRRNPGRKPLDDRAVLNGILVVLGRRIGFEKLPQDLEYGSGMTCWRRLRDWQRAGIWTDIAHILREEIPEARRIDFDRVIDTADTGTTEGETRVARRPRSTTLIRQPSPVAIEFGFTALRKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW3</accession>
    <name>C7QJW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4337</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4337"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM6">
        <property type="family name" value="Carbohydrate-Binding Module Family 6"/>
    </dbReference>
    <dbReference type="CAZy" id="GH87">
        <property type="family name" value="Glycoside Hydrolase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73201">
        <property type="protein sequence ID" value="ACU73201"/>
        <property type="gene ID" value="Caci_4337"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4337"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009451_0_0_11"/>
    <dbReference type="OrthoDB" id="32528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14490">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033801">
        <property type="entry name" value="CBM6-CBM35-CBM36-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983275" evidence="3">
        <location>
            <begin position="30"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="5">
        <location>
            <begin position="643"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="779"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="933" mass="94978" checksum="5C4B298E428633F9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK77</accession>
    <name>C7QK77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794880.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6297"/>
    <dbReference type="EnsemblBacteria" id="ACU75151">
        <property type="protein sequence ID" value="ACU75151"/>
        <property type="gene ID" value="Caci_6297"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6297"/>
    <dbReference type="eggNOG" id="COG4340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078728_0_0_11"/>
    <dbReference type="OMA" id="WQPVEYN"/>
    <dbReference type="OrthoDB" id="597962at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018724">
        <property type="entry name" value="2OG-Fe_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10014">
        <property type="entry name" value="2OG-Fe_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="26803" checksum="13EDC29ECD5DFA12" modified="2009-10-13" version="1">MTTDSAIFSVTLAAVKDLAESGTHLLGASEFSSLTNSTPQDWARFGQNWDDLKLDTYMADGGTYRYRRYDQFVVDVEAERIILLQHGPYRQEADINKLNGGIDRVYEPLTAAFLDDPLFRNILMELALIFSGVEDVKKWNVKVTPIRIIATQDQAGQPTPEGRHSDGATFITSLMIGRTNVVGADSSVYSPDGEALITTMLAEPGEILLSDDRRTLHDVTPVRPGEAGQPAHRDVLIMAYTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKN6</accession>
    <name>C7QKN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8312"/>
    <dbReference type="EnsemblBacteria" id="ACU77135">
        <property type="protein sequence ID" value="ACU77135"/>
        <property type="gene ID" value="Caci_8312"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8312"/>
    <dbReference type="eggNOG" id="ENOG5032G1K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_485575_0_0_11"/>
    <dbReference type="OMA" id="MELEMGY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="552" mass="53526" checksum="D2B536AEF0D32A77" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH6</accession>
    <name>C7PVH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784627.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0379"/>
    <dbReference type="EnsemblBacteria" id="ACU69332">
        <property type="protein sequence ID" value="ACU69332"/>
        <property type="gene ID" value="Caci_0379"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0379"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091682_0_0_11"/>
    <dbReference type="OMA" id="FPGRVHT"/>
    <dbReference type="OrthoDB" id="767622at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22548" checksum="84878274CFEF4CAA" modified="2009-10-13" version="1">MQLIKHAHACVSLVGDQGRIVIDPGTLTPDAAAAVAAAEAVLITHEHFDHFDEDMLAKALDARPELRVYGPASVVGRWEARRGQVTAVAAGDRHAVAGFDIAVFGELHALIHRDVPRVTNVGYLVDEKLYHPGDAYHVPEAPVETLLLPTSGPWTKLGEAVDYVREVAPKQAVQIHELLLAEVGQQAAKTMIGNLTEAAMAIVPVGEAITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD1</accession>
    <name>C7PWD1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4516</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4516"/>
    <dbReference type="EnsemblBacteria" id="ACU73379">
        <property type="protein sequence ID" value="ACU73379"/>
        <property type="gene ID" value="Caci_4516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4516"/>
    <dbReference type="eggNOG" id="COG1737">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055769_0_1_11"/>
    <dbReference type="OMA" id="QDLEHAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="38"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="163"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="32575" checksum="63F5C9C42A8FAF77" modified="2009-10-13" version="1">MSTGANRASRGGRGAGSGGAAVAAAGVSVPLIEAGPPPTVLVRIRALLPTLPPSERRVAEAAVADPAGVAAKTISELAADCDTSETTVIRFCRAVGLKGYPELRIGLAAAAGIEDAAVGAHTAGGDIGPGDSLADVVTKLGYADARAVEDTVAQLDLEVLERAVDAVVSAGAVDVYGIGASALIALDLHQKLHRIGHRAFAWPDAEAALTSAALLGRGDVAIGISHTGATPATVTALAEAHDNGARTIAITNFPRSPITDVADLVLTTAVRETTFRSGAMASRIAALTVVDCLFVGVAQRNFSRTTRALERTRSAVQGARGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX74</accession>
    <name>C7PX74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784720.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0473"/>
    <dbReference type="EnsemblBacteria" id="ACU69425">
        <property type="protein sequence ID" value="ACU69425"/>
        <property type="gene ID" value="Caci_0473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0473"/>
    <dbReference type="eggNOG" id="COG4320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032121_0_0_11"/>
    <dbReference type="OMA" id="QFRDMKD"/>
    <dbReference type="OrthoDB" id="571864at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="PTHR39441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="53347" checksum="CC5C89E835DF4D9A" modified="2009-10-13" version="1">MAESRRGVVTGRPYLTPEERVKRGRSARRDAPRSSHGEWEPAPDRRPVIDQLEAQASTSVADLVPIRYGRMIESPFRFYRGAASIMAADLASTPRSEMRAQLCGDAHLLNFRLLGSPERRLVFDINDFDETLRGPWEWDVKRLAASLAIAGRENGFDDHQREIVVRTMAGGYREAMRAFAGMTSLDVWYAHGSTERIRELYTDQLDAQRRKNFRRMLEKAKGRDSLQAAEKLTTTVDGRPRIVADPPLVVPLADLLPDLERGEVEAWIRDLVRRYSRSLRSDLRMLLDQYRVVDMARKVVGVGSVGTRCWIVLLAGSDEQDPLFLQIKEANRSVLADYAGESPYAHQGHRVVAGQRLMQAVGDILLGWKRGEDAHGGSHDFYVRQLRDWKGILESRTMVPHSMRIFGELCGATLARAHARSSDRIAIASYLGKGDGFDRALARFAEVYADQNERDHQALVEAVDRGRIRAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX97</accession>
    <name>C7PX97_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purA</name>
        <name evidence="8" type="ordered locus">Caci_0498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784743.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0498"/>
    <dbReference type="EnsemblBacteria" id="ACU69448">
        <property type="protein sequence ID" value="ACU69448"/>
        <property type="gene ID" value="Caci_0498"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0498"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477229_0_0_11"/>
    <dbReference type="OMA" id="RTYPIRV"/>
    <dbReference type="OrthoDB" id="666100at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="234"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="236"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="496"/>
            <end position="498"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="550" mass="60177" checksum="33A9FCA7AE1E547E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI0</accession>
    <name>C7PXI0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786726.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2515"/>
    <dbReference type="EnsemblBacteria" id="ACU71433">
        <property type="protein sequence ID" value="ACU71433"/>
        <property type="gene ID" value="Caci_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2515"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="GKAYMFF"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="94"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="35354" checksum="8891E967B0126EA9" modified="2009-10-13" version="1">MSQPIVVSPQPTAAVATGRARIRFRIPSTKVSIGLAILLLFTLVAFFGDALAPFDPSKRSNDILQSPSAKHWFGTTHLGQDIFSQILVGTRSVMFVGFFAGILATVIAVIVGVTSGYLSGFLGDSVSTLSNVFIVIPALPLIVIVTNVIPNSGDWAIALVIGCTSWAWGSRLLRAQTLSLRNRDFVQAAKANGESTWRIVTVEILPNLTAIIASSFIGTVMFAVMTEIALAYVGVSGISEWNWGEVLFWAQGQQALAIGAWWWFVPAGLCIALLGTALALVNFGIDEIVNPRLRGGGKAVVRTADGRKTRMRIGFTPVLTPRADIAESGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXQ7</accession>
    <name>C7PXQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2592</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2592"/>
    <dbReference type="EnsemblBacteria" id="ACU71510">
        <property type="protein sequence ID" value="ACU71510"/>
        <property type="gene ID" value="Caci_2592"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2592"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000908_0_0_11"/>
    <dbReference type="OMA" id="PDRWHIP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1501"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1573"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1818"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2454" mass="259233" checksum="917A183052D19F9F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXX6</accession>
    <name>C7PXX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4574"/>
    <dbReference type="EnsemblBacteria" id="ACU73436">
        <property type="protein sequence ID" value="ACU73436"/>
        <property type="gene ID" value="Caci_4574"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4574"/>
    <dbReference type="eggNOG" id="COG1378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056943_1_0_11"/>
    <dbReference type="OMA" id="TRFQAGM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="265"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="36330" checksum="2D1B91CC55C9A724" modified="2009-10-13" version="1">MLRPANKGTDVLESVGLPEPCGTVYSALVEHPESGAARLAEITRLPLSKVRGALDRLTAEGMASRAPGRTAVWFASAPDVAIGSLVGRAEQELVRVRSLMNGLMDSYREAARYTDPSLSVEVVRGYEEVGRRFSHLQSEARHQIRGFDRPPYLNNPGTNHDNAARRARSGLNYRVIYSRAALAWPDRLSQDIRPSQTFGEHSRTRPTLPIKMVISDDRQALIPIRDPEEALTTAYVIHPSSLLDALIALFEAEWRLALPLPEVSEQGPDEATRTLLLLLASGQTDEAIARALGWSFRTTQRRVQALMRTLDATTRFQAGMEARGRGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY9</accession>
    <name>C7PXY9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793178.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4587"/>
    <dbReference type="EnsemblBacteria" id="ACU73449">
        <property type="protein sequence ID" value="ACU73449"/>
        <property type="gene ID" value="Caci_4587"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4587"/>
    <dbReference type="eggNOG" id="COG4325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032303_1_1_11"/>
    <dbReference type="OMA" id="YVQHIDM"/>
    <dbReference type="OrthoDB" id="1749489at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018723">
        <property type="entry name" value="DUF2254_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10011">
        <property type="entry name" value="DUF2254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="465" mass="50897" checksum="5857C54A22E156E6" modified="2009-10-13" version="1" precursor="true">MRSARIALLALVSGQGAALTHVELRPGWRREALRTSLWWVPTLEVGAAFLLFWGGYLLDRAAYNGTLKLPSWVISGNADASRQILAALAAAVITVIGVVFSVILVALTLAANQLGPRMLRNFMRDRGTQWTLGTFVGTFTFAILVLISIGPGKHGDFVPHASISAVLFLALVDVFILIYFIHHIAVQIQLPYVIASIASDVVKAIEGEAAPPAGGPKLGPTPQEILATLKDEHGVVTASESGYLQYVSHSKLVRIATEADAVIHLLYRPGHFIVAGRLLATVTPPDAAPHVKEALRRAHLNGPYRSLTQDISFGIDQLVEIAVRALSQAVNDPFTALTCIDWIGDSLRQVALRWHPQVVHRDRAGYVRLIRTQASYDRLVRRGFEKVRQASGGVPSVMIRELQALKEIMAQAPRVEQYAVLREQADMIKTSAEQSIPEPRDLADVVSVYDELVALHERLLRETGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY43</accession>
    <name>C7PY43_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNF2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4642"/>
    <dbReference type="EnsemblBacteria" id="ACU73503">
        <property type="protein sequence ID" value="ACU73503"/>
        <property type="gene ID" value="Caci_4642"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4642"/>
    <dbReference type="HOGENOM" id="CLU_587534_0_0_11"/>
    <dbReference type="OMA" id="GRRHEYC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="351"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="465" mass="47126" checksum="63CC81811B5FE923" modified="2009-10-13" version="1">MSDELSGGGRPLCKFERLGRCSRPVKETLPGSRGRRHEYCDDPGHNAVTFNRARKAAARAEAAAAVGGAAGDAGGVAGGARAGMGSGAGGGFGGGAFGSGGLGIGAGGGVGGSVGGGMPVTAARAGFEASGVSVAATLRQLGAQVDLWLERAEAITDPENVERQVRSVELDAAARVTAAEQVAAAEAARRAEAEVAGQAANARAEQAGADAEVAREALDAAVVAHAEQEHTLRQDAAEELARVREQGEAAIAGMREQARREVEAARRDAAEAAELADRTRAEAALQLQAAREQAELVRQAADAQIAAAEGKAAASAAEAQAVAQRAAAELEALRAGLTAQIQSARADAESAHAARVTESERADREATARQAEAERAARAEAAAEGAAAQMEQVSARWQQDAAALAAEREARREAELMAASLRGELAAAARERDSAAAARERDGAAAARVPGGRVPDAGQREQGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY44</accession>
    <name>C7PY44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4643"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73504">
        <property type="protein sequence ID" value="ACU73504"/>
        <property type="gene ID" value="Caci_4643"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4643"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032381_0_0_11"/>
    <dbReference type="OMA" id="YANDFRM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="56215" checksum="FFF5F8710DEB606D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY81</accession>
    <name>C7PY81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin HHE cation binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6523"/>
    <dbReference type="EnsemblBacteria" id="ACU75371">
        <property type="protein sequence ID" value="ACU75371"/>
        <property type="gene ID" value="Caci_6523"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6523"/>
    <dbReference type="eggNOG" id="COG2461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095990_0_0_11"/>
    <dbReference type="OMA" id="RFFLWAY"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="12"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="24471" checksum="910297C9B7881A76" modified="2009-10-13" version="1">MSASGATSRVDTHDMVLIHRVLRREFGQLPRLFRSAANDRARSQVIGAHAREMLDFLHTHHTGEDELLFPLLRERAALDPELMDRMDAQHMQVDDAVKALEAELPAWTTSADADAGEQMATRVEATMPTLIAHLAEEEEKLLPIVSDTVTQSEWDTLAKHGMSAIPLTRRLVILGHITEEATEAERQRFMQVIPAPARLAYKLIGHRQFTRETAAIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYD9</accession>
    <name>C7PYD9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75429">
        <property type="protein sequence ID" value="ACU75429"/>
        <property type="gene ID" value="Caci_6583"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6583"/>
    <dbReference type="eggNOG" id="COG2314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_920384_0_0_11"/>
    <dbReference type="OMA" id="WRINISQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981345" evidence="2">
        <location>
            <begin position="22"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="30411" checksum="EB1627936135BAE4" modified="2009-10-13" version="1" precursor="true">MWVAGGVIALVVVVILSTVFGAKDTTKSASKASSTPSSTATSTRAPAKPSSTTHSSTSTPSPTTHSSTATAHPATHPSSTTPHPSPRPSSTSKPPATTTTSHAATAAPPVKAAGPAPTIAPISLAGSGQQTSRKFTVAGGLTEFTSSCADCDANFAVELLDATGNEVDLLANTIGTYTGTTAEGLPAGDYLLNVTADAAWNITITQPRAVSPVALPQAYNGKGDKVVGPFNAGGPFKVDGTNSGQANFAVKVIDANGDDVDLVFNEIGDFTGSDVAQTTFSSGPYYLVVTSDGTWRLALSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYG1</accession>
    <name>C7PYG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795180.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6605"/>
    <dbReference type="EnsemblBacteria" id="ACU75451">
        <property type="protein sequence ID" value="ACU75451"/>
        <property type="gene ID" value="Caci_6605"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6605"/>
    <dbReference type="eggNOG" id="COG4320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032121_0_0_11"/>
    <dbReference type="OMA" id="LGWHTVE"/>
    <dbReference type="OrthoDB" id="571864at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018721">
        <property type="entry name" value="DUF2252"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39441">
        <property type="entry name" value="PTHR39441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10009">
        <property type="entry name" value="DUF2252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="470" mass="51735" checksum="80E89197AF466991" modified="2009-10-13" version="1">MSTERRSHPTPAERVKAGKSARKAAPVEQNAQFQPAADRADPVAILEDQARTRVPELIPVRHGRMLVSPFTFFRGAAAGMAADLAATPDSGLTVQLCGDAHLSNFGMFASPERSLVFDVNDFDETHPGPWEWDVKRLAASLEIAGRDNDFGPKKRRRAVMAAARGYQQAMAEFAGMNQLDVWYARADIGELQDALKAGLTKARQKTFDKALAKARGRTSARAFGRLTGLVDGERRILPDPPLIMPVRDLVPDVERAELEEWFRELLAGYRRTLQSDRGCLLDAFEFVDMARKVVGVGSVGTRCWIVLMRGRGPDDPLFLQIKEAQQSVVAEYGGRPTAEPLGEGERVVQGQRLMQAVSDIFLGWQTVEGIDGQTRDFYVRQLADWKGSVVIEGLSPTELPAYGRLCGWTLARAHARTGDRIAIAAYLGEDEAFPEAVADFAALYADQNERDYAAMQDARRSGRISAESGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL9</accession>
    <name>C7PYL9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8518"/>
    <dbReference type="EnsemblBacteria" id="ACU77341">
        <property type="protein sequence ID" value="ACU77341"/>
        <property type="gene ID" value="Caci_8518"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8518"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="CVLHGTA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982706" evidence="5">
        <location>
            <begin position="30"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="68"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="39732" checksum="DC5120FE833D22A2" modified="2009-10-13" version="1" precursor="true">MRIRSLIAASTLAAGLLGPAGLAPSAAHADDTCRPADGQGVPNVPATVPWAQTALGLTDTGVWALSRGKGVVVGVVDTGVNPAGTVLPASAVQPGIDLLPGGGAGDVDCHGHGTMMAGVIAGRPGLATFEGVAPDATILPVTVTDESTNDPSAAARIGAGIKWAVDHGARVINISITTTPDTPALDDAVAYARDHRVLIVAASGNDQNAGPLYPASIPGVLSVGGVAADGSVYAQSEVGGHAGVAAPAAAIWSVGVQPTALTQPYVLSGEGTSYASAFVAGTAALILAVHPDLTPDQLIQRIEATADRPTTGYLPDPRIGWGVVNPYRAVTAELPNEPAASAPTTPQAMTLPVASAKHSDPVKRGAVLAVIGAAVLALAVPGAAAALRNGRRRGWKPGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN2</accession>
    <name>C7PYN2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797079.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8531"/>
    <dbReference type="EnsemblBacteria" id="ACU77354">
        <property type="protein sequence ID" value="ACU77354"/>
        <property type="gene ID" value="Caci_8531"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8531"/>
    <dbReference type="eggNOG" id="ENOG5030ITA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166724_0_0_11"/>
    <dbReference type="OrthoDB" id="1884729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13103" checksum="EB8E2EFEE06E0127" modified="2009-10-13" version="1">MPEPIHIARVSVDNGAAGPRLEDAERERVAAFLAAGAPILLTTALGQDKLDPARGTVVGASFRTDGTWVWSDGVEYYVRVHGVAPEDALLLWIRGQDYRCATPDEPAQDLALDALWASFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYR7</accession>
    <name>C7PYR7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="1">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tadA</name>
        <name evidence="3" type="ordered locus">Caci_8570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8570"/>
    <dbReference type="EnsemblBacteria" id="ACU77389">
        <property type="protein sequence ID" value="ACU77389"/>
        <property type="gene ID" value="Caci_8570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8570"/>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_3_2_11"/>
    <dbReference type="OMA" id="PCQMCAG"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="16768" checksum="C98D87B120EA57DA" modified="2009-10-13" version="1">MRLALAEATAAESTGDVPIGAVILDPTGTVIAQGRNTREAEGDPTGHAEIVAIRSAAHTLHTKAAQTDPKAPPTWRLTDCTLVVTLEPCPMCAGAIVLSRLTRVVFGAWDPKAGAAGSLYDILRDPRLNHTPEVIPGVLEPQCHAALNRFFEHHRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ05</accession>
    <name>C7PZ05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784856.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0625"/>
    <dbReference type="EnsemblBacteria" id="ACU69561">
        <property type="protein sequence ID" value="ACU69561"/>
        <property type="gene ID" value="Caci_0625"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0625"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_12_2_11"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982630" evidence="1">
        <location>
            <begin position="39"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="46615" checksum="14E05C302B325A27" modified="2009-10-13" version="1" precursor="true">MRTSKNVHRAGVIAAAVAVSAASLSACGSSSKPGTSSGAKSSGSTSFTYWSMWQQNEPQAKVIKKAADDFTAATGIKVTIQWQGRDVITKLTPTLRTGSSADLVDQSVNALGALVAKDETTDLSSLYGTTIPGESQTVGQVIPDSYKPFLNDKNGKPFIAPYEVSSEGLWFDASKFPALAANPPKTWDDLLALFDKAKGMGMTPVAVPGDDKYWVLLTLQRELGTDTLKKLASDKTGAAWDDPKVLKAAQLVQAMRDKGDFLKGYESSKSIDEEGDWAKGQAAFYLSGTWVPSEAAPNAAAGFTFDSIQLPALDSGNTDTGINFFGFAVPKTAKHSDAAEKFVAFFMKKEELSGISTQALNLTPRADIAPPAQLASMSKALTGTVYADQAHLSVDYADWTNKMLNPEMIRLITGQDDAAKFVANGRQGTIDYWKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ59</accession>
    <name>C7PZ59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784910.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0680"/>
    <dbReference type="EnsemblBacteria" id="ACU69615">
        <property type="protein sequence ID" value="ACU69615"/>
        <property type="gene ID" value="Caci_0680"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0680"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_360826_0_0_11"/>
    <dbReference type="OMA" id="DLGVCKA"/>
    <dbReference type="OrthoDB" id="324902at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="669"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="721"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="774"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="294"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="707"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="809" mass="81831" checksum="5B1ADF6D1963927A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ76</accession>
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        <submittedName>
            <fullName evidence="2">Hydrophobic protein</fullName>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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    <dbReference type="HOGENOM" id="CLU_210462_0_0_11"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="58" mass="6374" checksum="9B5879F57AB31615" modified="2009-10-13" version="1" precursor="true">MGVILLVLLVALLLGGLGFAAHALWWIAVIVFIAWLVGFGVSRGEAHAGGRRRWYGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC6</accession>
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        <recommendedName>
            <fullName evidence="1">DUF1330 domain-containing protein</fullName>
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        <name evidence="2" type="ordered locus">Caci_2667</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU71583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Caci_2667"/>
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    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
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        <property type="entry name" value="DUF1330"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="10369" checksum="3970BB8B4A24834B" modified="2009-10-13" version="1">MAKGYWVSAYRTISDPEKLAAYNELAGPAVRAGGGRTLVRGGRTVAHDAGIAERTVLIEFDSFDQAVAAHESEAYQEALAALGDGVERDFRIVEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZV9</accession>
    <name>C7PZV9_CATAD</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4763</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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            <taxon>Catenulisporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4763"/>
    <dbReference type="EnsemblBacteria" id="ACU73624">
        <property type="protein sequence ID" value="ACU73624"/>
        <property type="gene ID" value="Caci_4763"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4763"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_2_2_11"/>
    <dbReference type="OMA" id="AMIPAFF"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="34"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="169"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="32358" checksum="50A7B4900D16D0F1" modified="2009-10-13" version="1" precursor="true">MTATTVSTTAPATSPARAGGTGSGAGTGTARDLLLSVLAPASWGTTYVVTSEFLPDHRPMLAATMRALPAGLILLAFVRRLPKGSWWWKTAVLGTLNFGAFFPLLFFAAYRLPGGVASTLGSVQPLLVAGFSILILRQRPHSAVLGAAVVGTGGVALMTLTAKARLDALGVLAMLVATALMALAVVLGRKWGRPEGATPMVLATWQLVFGGLVLLPMTLLSEGLPDTLTARNLAGFAYIGVVGTAVAYTLWFRGIERLAPTSLSLLSLANPMVATVAGFVVLHQSLTAPQAAGFAVALGALVTGQMLVARRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q053</accession>
    <name>C7Q053_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795275.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6700"/>
    <dbReference type="EnsemblBacteria" id="ACU75546">
        <property type="protein sequence ID" value="ACU75546"/>
        <property type="gene ID" value="Caci_6700"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6700"/>
    <dbReference type="eggNOG" id="COG4916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048818_0_0_11"/>
    <dbReference type="OrthoDB" id="1587806at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="34052" checksum="514EB4E19D3C13A2" modified="2009-10-13" version="1">MPHHPDGRGPAVFISYATADRTEVLKFHQDLLERGIDPFLDIMDILPGDDVVMSINGALERSDFYVLVWSAAARDRYWVNSEISAAMVLEQRRARPFVFIVRLDDSELPPVLAPRRYLDAFGGRRQAAAEQLTAVWTRDRAVGTKVLPAPAPVREPSPRDEHEQHEQTIHIYARNQSLQVSHEVRIPVGATSRQLVAALSEQLALPTEASEYGGAVGVRFSYRYQHAGELFAEDSDVVLGLTEGDVVDIEVVVEPFGPDGALADPVSFLPGRDYAIPPEMIRELCEKAIEHLLAEDPDDNQHSDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q086</accession>
    <name>C7Q086_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6733"/>
    <dbReference type="EnsemblBacteria" id="ACU75579">
        <property type="protein sequence ID" value="ACU75579"/>
        <property type="gene ID" value="Caci_6733"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6733"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="HERIAWI"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="354" mass="38052" checksum="032E16CC6A4D1998" modified="2009-10-13" version="1">MSQPEQSPARPTIKAVAKHAQVSYQTVSNALNAPERLRPDTLARVLRAVEDLGYRPTQAARNLRLQTTRLIGFRSTRSGGRDIGAIEDRFLYALTSAARDRGYGVILFAADGDEDEIAMFEDLVSRGAVDGFVLFGSHRHDARTAWLAERDVPFVSFGRPWEKTAFEYSWLDVDGHAGTLAATRHLAAAGHRRVAFLGWPEGSEVGDDRYAGYLAAAEELGLPTRGLTVRGLNGIGDGTKLAAALLDKAHPPTAFVCVSDAMAVGVMHAVEHRGLAVGRDVAVIGFDDSPLATVVQPALSSVRQPLESIARQCVDLVLERIDDPRSAVTTSVVEPTVIARGSSDPTHPAPDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0E9</accession>
    <name>C7Q0E9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8667"/>
    <dbReference type="EnsemblBacteria" id="ACU77482">
        <property type="protein sequence ID" value="ACU77482"/>
        <property type="gene ID" value="Caci_8667"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8667"/>
    <dbReference type="HOGENOM" id="CLU_2258667_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="10750" checksum="91AF9D029D01C1D8" modified="2009-10-13" version="1">MSDDNLKMDADALDGFTAQLNSLIRDGSATMFPASFHGEMGDGGVENAISDMASTDMSIGQRLNNYLSALAGLTGASAKATRDMDKQLADSVTNPPHGKLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0J4</accession>
    <name>C7Q0J4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797251.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8712"/>
    <dbReference type="EnsemblBacteria" id="ACU77527">
        <property type="protein sequence ID" value="ACU77527"/>
        <property type="gene ID" value="Caci_8712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8712"/>
    <dbReference type="HOGENOM" id="CLU_2877532_0_0_11"/>
    <dbReference type="OrthoDB" id="2090243at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="6954" checksum="890D19879F215094" modified="2009-10-13" version="1">MSENSGWDADERVVDWDELFGDVLPEQTTDDLGDRDPSSTSGAGGDTARLMELLADRPPHYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Y3</accession>
    <name>C7Q0Y3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786951.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2745"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71658">
        <property type="protein sequence ID" value="ACU71658"/>
        <property type="gene ID" value="Caci_2745"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2745"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735073_0_0_11"/>
    <dbReference type="OrthoDB" id="1900597at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981372" evidence="1">
        <location>
            <begin position="28"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="2">
        <location>
            <begin position="269"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="38047" checksum="4A45AC68A9A95D77" modified="2009-10-13" version="1" precursor="true">MLRRLLMSILAAVVSLAGLLVPVAANAATTPGCTGGVSVSQFTFNPSSVPLGGHSELTLVLQNCGSQTVQGSTIWYGQFAGQGCPVLDPANPSPFTIAPQGSLTLSKTYGDPGLTGCHPTSLHMSTGVSVTGVGTVATPTATLQFVPACDGDTGFAVDRLDFSPVAVAPGRLSTATLVLQNCTAQTVTGSTTWIPRLTGSGPDLPPGCPALDPVAFPASIAPGATATATLQLGDPVASCLATGLLLTVNVYETGVTNPVYIAQANLGIIQPAPDSCHVTYTPANWPGGFTANVTITNTGTAAINGWTLGFTFPGDETVTHGWNASVTQKDTTVTASNLAYNATIAPGASQSFGFQGTWAADNTPPATFAVNGELCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q228</accession>
    <name>C7Q228_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797289.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8750"/>
    <dbReference type="EnsemblBacteria" id="ACU77565">
        <property type="protein sequence ID" value="ACU77565"/>
        <property type="gene ID" value="Caci_8750"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8750"/>
    <dbReference type="eggNOG" id="COG1062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_11"/>
    <dbReference type="OMA" id="GRPTMCR"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="4"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37908" checksum="E13759C79E1DFE3A" modified="2009-10-13" version="1">MRAAVFEGGKLEVVDGIEVRAPRTDEIVVRVGAAGLCHSDLSVVNGTIPFPGPAVLGHEGAGVVEEVGGAVTRVKPGDHVCLTTINHCGVCPACSEGRPTMCRATFGKISKPFTREAADGTAEKLFAFANTSVFTERVVVKEVQAVPIPEDVPMASAALVGCGVLTGVGAVLNRAKVRIGETVVVIGVGGIGLNAIQGARIARAGRIVAIDTNPRKEEAARRFGATDFLDPSGQDAVELVKELLPRGADYVFECVGHPALIRAATDMLAWSGAAVLLGVPRSDAEGTFLVSGMYMDKTIMGCRYGTSHPQFDVERYVDLYRKGELLLDELVTKTYPLEHIHEAIHDLESGSLARGVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q278</accession>
    <name>C7Q278_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797339.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8802"/>
    <dbReference type="EnsemblBacteria" id="ACU77615">
        <property type="protein sequence ID" value="ACU77615"/>
        <property type="gene ID" value="Caci_8802"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8802"/>
    <dbReference type="eggNOG" id="COG0738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="FCCNFSM"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="42577" checksum="723A75897C76BEF8" modified="2009-10-13" version="1">MTADFPKFWFGETVSLLGTQVSNLALPLTAISTFHASNAEVGVLRFLQLAPYIGFALVFGAWADRVRRRHVMIATNLVRMALVGVVPALAARHELSMPLLLVIACAVGVASVMFDVSWMPYAPTLVDGDERRYVEISAKMGMSSSASDVAGPGLAGLLVSVLSAPTALVVDACSYAVSVTSLLAIRKQEPRPTPTAQRNLPREIREGLAWVFGTRILRWLAFVGFCCNFSMITVWTMFLLYGTQELHLAASTLGAIFATASVGGLIGAMVSRAVIARFRLGRVYFCAQTALLAGPTLIAVAGGPKAVVVALVTGSFFTTYLGLGIANVVIVSLRQAATPQALLSRMTACFRMLLFGGGALGGLTAGLLSGAIGDRDALIAAAVFSAAVVVALALSPVSRLRELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Z0</accession>
    <name>C7Q2Z0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA_lig_T4_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787175.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2973"/>
    <dbReference type="EnsemblBacteria" id="ACU71882">
        <property type="protein sequence ID" value="ACU71882"/>
        <property type="gene ID" value="Caci_2973"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2973"/>
    <dbReference type="eggNOG" id="ENOG5033AFQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_779938_0_0_11"/>
    <dbReference type="OrthoDB" id="979392at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="RNA_ligase_T4-Rnl1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_lig_T4_1" evidence="2">
        <location>
            <begin position="61"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="41465" checksum="9E55705CF7935C38" modified="2009-10-13" version="1">MTTTTTSPLHLHDLFSPADLQAEIEAKFVTRKQHPTLPLSLYVYGQSCQYEHHWTPVTMCCRGLIVDDTTGRIVALPFPKIFVTGMHGVHDFAPPLPTEPFEIFEKVDGSLIIAFHYDGRWHAASKGSFASEQSAWAQARLDAADTSLLDPALTYLAEAIYPANRIVVDYGAREDLVLLAAYEPATGAEKALAKVAAHWAPIGPVVRSWGLGKDVREVEVLAADSRRIDGRTAGGTEDEGYVIRFTSGIRAKIKLSSYLALHKLYTGTNERTVWEVLASGQDPAVLFDTVPDEFAGWVRQVAARLRGEFDAYVAAARADFDAIGPTAERKSFAEQAMKSEHRAALFRLYDGRDIDDLAWKSIKPRGDVPFVTDEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q311</accession>
    <name>C7Q311_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787196.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2994"/>
    <dbReference type="EnsemblBacteria" id="ACU71903">
        <property type="protein sequence ID" value="ACU71903"/>
        <property type="gene ID" value="Caci_2994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2994"/>
    <dbReference type="HOGENOM" id="CLU_1913303_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14579" checksum="9E30F2DF4284089D" modified="2009-10-13" version="1">MTDTTTPTAAEQAAAHLIEKLERMANNSVSLATYFENAAKATRSREWISKHKESAEFHRAFASQVDEVLYRLITQAGGYPGIPGDGWRDNEGDVWVLCADNMLRLLDDETTSRDPDDLAGEYGPMEPVGSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R4</accession>
    <name>C7Q3R4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane-bound metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797396.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8859"/>
    <dbReference type="EnsemblBacteria" id="ACU77672">
        <property type="protein sequence ID" value="ACU77672"/>
        <property type="gene ID" value="Caci_8859"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8859"/>
    <dbReference type="eggNOG" id="COG1988">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071993_0_0_11"/>
    <dbReference type="OMA" id="CRFVAWA"/>
    <dbReference type="OrthoDB" id="1667936at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="25343" checksum="E2512B928403675A" modified="2009-10-13" version="1" precursor="true">MLGHSHATSGGLAWAAASSALPMSILAYPAMHGSTAHIQARDLIFGTFITAGAALLPDIDHPNGTIAHAIGPVTHNLCKVIEKISGGHRHATHSFAFVALVAYGTWAGEHYIGRYFTLGLVFFMLALAARSLNLCPPGEGLHAYGPCILLAGGGTVLMDRWIASAPSWLPFAIGLGALTHLAGDCLTDHGCRLFWPFTLRTGIPLIKRTGNKMETWFLAPAMAVGCAVLLYMKTSGKTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W7</accession>
    <name>C7Q3W7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_8912</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8912"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77725">
        <property type="protein sequence ID" value="ACU77725"/>
        <property type="gene ID" value="Caci_8912"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8912"/>
    <dbReference type="eggNOG" id="COG0744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006354_2_6_11"/>
    <dbReference type="OMA" id="VHGMGLA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="81"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="366"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="694"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="700"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU77725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="740" mass="77925" checksum="B504A33B8380398B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3X7</accession>
    <name>C7Q3X7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797459.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8922"/>
    <dbReference type="EnsemblBacteria" id="ACU77735">
        <property type="protein sequence ID" value="ACU77735"/>
        <property type="gene ID" value="Caci_8922"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8922"/>
    <dbReference type="eggNOG" id="ENOG5034BSV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127701_0_0_11"/>
    <dbReference type="OMA" id="RFMDMSA"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="15828" checksum="F9B594321D81F002" modified="2009-10-13" version="1">MAATAEDASAKELPFVAKRLDLLFRIASEKAGRKIGAGVVAEGINAAAGEKVIEQSYIWQVRTGRKDNPSYKVLMQLAGYFGVHPAFFFPDDSENVIDPDLQVALRDERIRNLALLAVGLSDPSIEAVTMIAKNSRSLEGLAERPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q450</accession>
    <name>C7Q450_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785204.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0979"/>
    <dbReference type="EnsemblBacteria" id="ACU69910">
        <property type="protein sequence ID" value="ACU69910"/>
        <property type="gene ID" value="Caci_0979"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0979"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066193_0_0_11"/>
    <dbReference type="OMA" id="GIMRRAP"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="173"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="30558" checksum="6FA42C7FF0DDF63F" modified="2009-10-13" version="1">MESVRREPVPVLRGLVYRHTGFHLPDAAERARLELPSGAATMLIAFAEPIRIGLVSEGESEVFQRTSFLSAGRAIAAIGRHRGRVHGMELTLSHTGAHHILGVRMAELAEGFPTLGEVLGREGELLVEQLASLPSWEARFATLDAYLARRAADSQVQASWQVTRATRLVAAGWSLRDIQRDVGWGERHLRSRFLDQVGMTPKAMARVLRLQTALRAYLSGRNWAQAAVLARYHDQAHLGHDVKAITGLTPGRLAELRRGAPPGSALDRLPGRVTSVLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4L4</accession>
    <name>C7Q4L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787276.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3074"/>
    <dbReference type="EnsemblBacteria" id="ACU71983">
        <property type="protein sequence ID" value="ACU71983"/>
        <property type="gene ID" value="Caci_3074"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3074"/>
    <dbReference type="HOGENOM" id="CLU_1114250_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="25252" checksum="8E0B64C825895798" modified="2009-10-13" version="1" precursor="true">MSAQTSTSTPEATAGSSASGSSAVGSGASGSEAGASNGSSGRAGTSSSAADVGVGFLLLTSRTFWAGYGIVLAIMGTRLPMWSWPPKSGQIIELLFCAIVFPALAQPYVGRPVLAAMRLHQIAGVHRNTLLVGAFVTLVACEKPQPWAAGVDALLLTGYLVLTDSITVPLRVLQRIASPAFLLALVAVIAGTTALVALPASSGSYRPALVAVAAAAALGSAVATAFGSAEERRVGSQRTERRNQDRPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4P6</accession>
    <name>C7Q4P6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_3106</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3106"/>
    <dbReference type="EnsemblBacteria" id="ACU72015">
        <property type="protein sequence ID" value="ACU72015"/>
        <property type="gene ID" value="Caci_3106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3106"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="YERADAM"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU72015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="538" mass="56315" checksum="AA8DD42BEAED4A50" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q595</accession>
    <name>C7Q595_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795592.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7034"/>
    <dbReference type="EnsemblBacteria" id="ACU75864">
        <property type="protein sequence ID" value="ACU75864"/>
        <property type="gene ID" value="Caci_7034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7034"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="GHDHVHP"/>
    <dbReference type="OrthoDB" id="1721927at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="25"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="29628" checksum="75B6577D2068B328" modified="2009-10-13" version="1">MARRSAGDAAIAAGPPEDPPPAPVVDAQQVTVSLGGRRILHGVDLEVPGGQTVALLGANGSGKSTLVKTIVGLYPPDGGGIDLFGTPLSAFKAWERVGYVPQRTTAAAGVPATVGEVVASGLLSPRSWMARRSRGDRSAVREALATVGMLDRIADPVASLSGGQQQRVLIARALARRPDLLIMDEPMAGVDLVSQQTFADTLADLSRHGTTILLVLHELGPLAPLINRTVVLRAGTVRYDGAPIEHGEPDHDHVHPHAAPPNRPGTPECPPGHAPVEALSGKEGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5C6</accession>
    <name>C7Q5C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7065"/>
    <dbReference type="EnsemblBacteria" id="ACU75895">
        <property type="protein sequence ID" value="ACU75895"/>
        <property type="gene ID" value="Caci_7065"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7065"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_5_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="433" mass="44857" checksum="0392C389A451B2D6" modified="2009-10-13" version="1">MSLLPHDRVQRTMAVATFVNTIGNGMYMTVMVMYFTRSVGLPASQVGLGLTIAGLFGLAAGVPVGHLADRRGPREVSVVLGMLAGAVMVAFTMVHTFWQFLAVAVVENLVASSNRAARGAMIARFGGEEKAVFRAYLRSVTNVGIALGGVAGGLGLVFDTRAWYVGLIGFNALTFVVSSVIALRVPRMEPLPVPHGANKWIALGDRRFLTSAALIGVMSMQFEVLLFAAPLWIAKLGHAPRWTVGAVLVINTVLVATLQVRMSRGVDTVAKGVRATVRSGWIFAGAAVLFGSIGWVPAWAAVVLLLVAAAVHSIGEIVQQAGVFELGYELAAEHAQGQYQGLLSMVTGAAMSLAPGFYALACVDWAPAGWFVVGAVFAVAGCAMPLAVRIRPPAFLAATEAAAAAAVAATVAAATLPTAAPAAPIAVAEVPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5H4</accession>
    <name>C7Q5H4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8972</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797509.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8972"/>
    <dbReference type="EnsemblBacteria" id="ACU77785">
        <property type="protein sequence ID" value="ACU77785"/>
        <property type="gene ID" value="Caci_8972"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8972"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009273_4_6_11"/>
    <dbReference type="OMA" id="IACCMLK"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="14"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="364" mass="40726" checksum="388FA5F5A92E843B" modified="2009-10-13" version="1">MPATLTADAVHATAVKEPFLFLYITEHCQLRCKHCYMGDRLDMARRMTPERVEEILSTLRIAYGQYKVYLLGGEPTTHPQLEQILDICEQQNYKVVLTSNGLIPQKVWPVLEGRLDSFSFSMDGAREQTHEAMRGPNTWRPLVGSMRRAIDAGFQTRAIFTITSDNVADVQDAIAFADDLGLEMLSFHYFTPTGLGLDKPHLQLPPERWMELCDQITGWAAGRRLRVFFPPSFVPAARLPVLAAQGYRGCTARNLERLAIFPDGRVYICSAFFDTDLHYGTFRDGVIEPRTATGPTELTLVNKISANCRGCGHADVCGGGCAAYDHLNRTLVSSECDRTTIPICPLWSMPAEPANTEHRLVDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6A5</accession>
    <name>C7Q6A5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787404.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3204"/>
    <dbReference type="EnsemblBacteria" id="ACU72111">
        <property type="protein sequence ID" value="ACU72111"/>
        <property type="gene ID" value="Caci_3204"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3204"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1169007_0_0_11"/>
    <dbReference type="OrthoDB" id="1260859at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982935" evidence="1">
        <location>
            <begin position="35"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="237" mass="24860" checksum="09F9E2056E138769" modified="2009-10-13" version="1" precursor="true">MQRISTKRGLAAGLATAAVAAGIAALGTGGSAAADTTATSAVSAGPATYSQAVPTGQPSQYSSPLERCANGVDHPLSGANPILAEPLTTQFSSNVGLSEAVSYSGDQWYGNWTFTFTNTSSETLATDCAVLIWRAPSSSDNHAYTASVAYGHPQQDYLEVPRGDGTSFYVARLGFHDVPLNQRQVGPGQKFTYTWGGVPSTAITTQQIRDSLRFTADLNLSGNQSMVLHYGTDRLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B1</accession>
    <name>C7Q6B1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3210"/>
    <dbReference type="EnsemblBacteria" id="ACU72117">
        <property type="protein sequence ID" value="ACU72117"/>
        <property type="gene ID" value="Caci_3210"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3210"/>
    <dbReference type="eggNOG" id="ENOG50344YS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699597_0_0_11"/>
    <dbReference type="OMA" id="GATAHCE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982832" evidence="3">
        <location>
            <begin position="23"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="394" mass="39859" checksum="C8884AB4D4398228" modified="2009-10-13" version="1" precursor="true">MTPLASPVSILCAVLGTLPVSALFSGTDCHHPRLELSVTVNGRPASPDPLIRTGNPVRVVYRITNPDDRDVLDVHLAAPGETIVCPSGSADVPRLDDHSSVVCVAVLTAAPGVHDGTATATGHVRDGWPFDDDDGHGLGHGHGDDDWDRSVTASTAVGYRGVGGLISATDSVSVTPTASGGKATLVYTVTDTGNLPVYDVVLSDPLVPSGRITCTGLSAGIQPGATAHCEAVVDLAPGSHISTLSVNASDHTSTAGSSGSSVPPPTLSASAAARFTVVALPPPPPRPSPSPTPTPTPTPVPPPPSTPPRPSAPRPTPTPTPTPTPTPTPTPRPTPTPTPTPRSTPPAPSPSQTTIPPVAKPEQLSRPGVKTSLFLLVMMMPAAGAAAVLAARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6K1</accession>
    <name>C7Q6K1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793765.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5177"/>
    <dbReference type="EnsemblBacteria" id="ACU74036">
        <property type="protein sequence ID" value="ACU74036"/>
        <property type="gene ID" value="Caci_5177"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5177"/>
    <dbReference type="eggNOG" id="COG5426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025386_1_0_11"/>
    <dbReference type="OMA" id="NATWIRS"/>
    <dbReference type="OrthoDB" id="308398at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046306">
        <property type="entry name" value="DUF6421"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19985">
        <property type="entry name" value="DUF6421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="710" mass="77966" checksum="D45E6889A6229D31" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6L4</accession>
    <name>C7Q6L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793778.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5190"/>
    <dbReference type="EnsemblBacteria" id="ACU74049">
        <property type="protein sequence ID" value="ACU74049"/>
        <property type="gene ID" value="Caci_5190"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5190"/>
    <dbReference type="eggNOG" id="COG2968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1287630_0_0_11"/>
    <dbReference type="OMA" id="GPWWSLR"/>
    <dbReference type="OrthoDB" id="1821429at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="25258" checksum="95EDF0409AA6CF4D" modified="2009-10-13" version="1">MTDQTAGTPIVVSVRGEANVEADPELCEFAVTVTARDKDRRTALEQLTRRNKDLLDQLKAEYGEALEKLETGRFSVYPEWRTKRDKPGPYQGSVRIRIVVKDFTILGEMVTRIADAEGRTIDGPFWSLRRDSPVYRTARTEAVTEAIRRAREYTAALGSHLTTLLELADTGLSTGATPAPHTRMMYTMSGAAPGAMPDEGPPALDLEPTRQTVYAAVEARFSATQPAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q764</accession>
    <name>C7Q764_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785446.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1227"/>
    <dbReference type="EnsemblBacteria" id="ACU70152">
        <property type="protein sequence ID" value="ACU70152"/>
        <property type="gene ID" value="Caci_1227"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1227"/>
    <dbReference type="eggNOG" id="ENOG5034AHG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2192280_0_0_11"/>
    <dbReference type="OrthoDB" id="1956964at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11879" checksum="F859724DB2BA4201" modified="2009-10-13" version="1">MSFIAKCLEITEKSFEGTVEQLEEWSAHRHGAKLFMKLGIAYYAEQRLEGHHEPVARILDALDGHAAEHGETGIDHLRITHEVLGREFAGEHHPEAAAEKDAAANAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q792</accession>
    <name>C7Q792_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU70180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ACU70180">
        <property type="protein sequence ID" value="ACU70180"/>
        <property type="gene ID" value="Caci_1255"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_2_11"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="273"/>
            <end position="340"/>
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    </feature>
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            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="463" mass="49629" checksum="5C41C5E1AEDE055D" modified="2009-10-13" version="1">MLATRGAEISSATWRFRGGASTTPGVRQARWTGAELRQYREGVPMTREILRARWSQAGGDALFLVTGLPLWAAAMMVLLVWSQPAYLLLQAEDPGVLRFGVSVVIVLAAVLTLAPFLTRWHRIRFRTFRSTEILEIDTPRLYRGQLRQALRSEALWRQALYHLIAGPLIGIAVVALAFMDLLAIVVAARLPAHALGLLDPGHGVSSKFWGQCAYILLAGTVTYSGPRLLRVLADADLGAARRLLGPSETIVLAHRVQTLSDSRAAAVEAADTERRRIERDLHDGAQQRLMSLAVHLGIARKTLKDVPPEAMSVIIDAHEQVKDAMAEIRDLVRGMHPAVLDDRGLDAALSGVAARSAVPVRLTVGTTGPLSASVETVAYFVVSEALANVVKHSRAKQATVDVTRDDGRLLIRVSDDGVGGADAHGGTGLTGLAQRVASVDGLLRLTSPSGGPTVLTAELPCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7G7</accession>
    <name>C7Q7G7_CATAD</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Caci_1332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1332"/>
    <dbReference type="EnsemblBacteria" id="ACU70255">
        <property type="protein sequence ID" value="ACU70255"/>
        <property type="gene ID" value="Caci_1332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1332"/>
    <dbReference type="HOGENOM" id="CLU_312774_0_0_11"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="28"/>
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            <begin position="350"/>
            <end position="372"/>
        </location>
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        <location>
            <begin position="392"/>
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        </location>
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            <end position="449"/>
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        <location>
            <begin position="502"/>
            <end position="525"/>
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        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
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        <location>
            <begin position="867"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU70255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="937" mass="95468" checksum="DE52B94A08E2AD90" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7W6</accession>
    <name>C7Q7W6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-rhamnosidase</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Caci_5274"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
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            <end position="897"/>
        </location>
    </feature>
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        <location>
            <begin position="255"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU74133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="897" mass="92805" checksum="EC2B6745AAB66168" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q871</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            </authorList>
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            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7230"/>
    <dbReference type="EnsemblBacteria" id="ACU76059">
        <property type="protein sequence ID" value="ACU76059"/>
        <property type="gene ID" value="Caci_7230"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7230"/>
    <dbReference type="eggNOG" id="ENOG5032YW5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064093_2_0_11"/>
    <dbReference type="OMA" id="GPYASRM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="35929" checksum="300FABE39FAA6B18" modified="2009-10-13" version="1">MAKRRGPGEGNLKLVWDPAGRDRWLATTTQELRVGRYTLAGELLADRQAGEDIRDYRYLILAQIAASNGVDTAWLAEEPDSAEAALLRLRANVIRALQAHRAQHPRAYGLIDLTRKQCLEAADRFPDDPLPWIALLHLAPAAPDNVPGPPELSIDGPWETMGQLWRRDPWNREAHHRLLAAVGPKGGGSVSALTTVAHWIASQAPAGSALLGLQLVAFIEAFRQQLERSDLNKVLLTYRNWSTAYAEQETERCYTHWFSPTSGNGALLPDLHHLAHALWAGSQWRPAAHVFDAIGPYALTMPWSLHGNPEQVLVTARERCVSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8G8</accession>
    <name>C7Q8G8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7327"/>
    <dbReference type="EnsemblBacteria" id="ACU76156">
        <property type="protein sequence ID" value="ACU76156"/>
        <property type="gene ID" value="Caci_7327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7327"/>
    <dbReference type="HOGENOM" id="CLU_3150831_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="48" mass="5397" checksum="0E0852D6D19DD364" modified="2009-10-13" version="1" precursor="true">MKDILGFLVMLAMLGWFAMGVVQVLKTLWLYGVVAVVVLSLLVFFARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W4</accession>
    <name>C7Q8W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785673.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1456"/>
    <dbReference type="EnsemblBacteria" id="ACU70379">
        <property type="protein sequence ID" value="ACU70379"/>
        <property type="gene ID" value="Caci_1456"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1456"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_2_11"/>
    <dbReference type="OMA" id="MAPQDTG"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983030" evidence="1">
        <location>
            <begin position="25"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="41"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="36456" checksum="D746176AF5827C1C" modified="2009-10-13" version="1" precursor="true">MRLHRTSRSVMALTAVVALGLSAAACGRGGSKSDSGGKKIGIDFPRSDSDFWNSYAKYVNADVKSGSMNALPPTNSNNKTDTLVSNVTTLTGQGAKVIVMAPQDTGAIASTLDSLASKKIPVVSVDTRPDKGQVYMVVRADNKAYGTKACQFLGDKLKGTGTIVEFEGDLTSINGRDRSQAFGDCMKQNYPNIKVEAEPTNWVGDTAAAKLQDALNAGTVNGIYMQAGGVFLAPTLSLLKQKNLLVPPTDPKHIFIISNDGIPAEFQAIKAGQIDATVSQPADLYAKYALFYAQAAAQGKTFAPGPTDHNSTIIQLPNGLEDQLPAPLVTSANVDDSSLWGNQVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q912</accession>
    <name>C7Q912_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787625.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3426"/>
    <dbReference type="EnsemblBacteria" id="ACU72332">
        <property type="protein sequence ID" value="ACU72332"/>
        <property type="gene ID" value="Caci_3426"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3426"/>
    <dbReference type="eggNOG" id="COG3208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070456_1_1_11"/>
    <dbReference type="OMA" id="FADELNH"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="27017" checksum="B86E69827DE7B4EF" modified="2009-10-13" version="1">MTQPSTRWLLQEPSPGGRPLLFAFPYGGSGASSLRRWPGRIGEAEVHAVQLPGRENRIKDLPCRDFAAFAEEAVRELGPYLDRPYAVIGHCMGALLAHAFTFRAQQSGAPMPNRLFVSASLVPQRGFYGLYHPWMSDRRIAQELRRVSTGLGDGELPDEVVALSVPVLRRDVRMCLDYAPPPQPVDVPVTAIGWSRDLDVGPADLAEWRQLAKSREVMLPGEPLAFLTAPRELRAVVEDDFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9B4</accession>
    <name>C7Q9B4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793989.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5401"/>
    <dbReference type="EnsemblBacteria" id="ACU74260">
        <property type="protein sequence ID" value="ACU74260"/>
        <property type="gene ID" value="Caci_5401"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5401"/>
    <dbReference type="eggNOG" id="COG5032">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085318_0_0_11"/>
    <dbReference type="OMA" id="WPAIPWP"/>
    <dbReference type="OrthoDB" id="1421354at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022292">
        <property type="entry name" value="CHP03843"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03843">
        <property type="entry name" value="TIGR03843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="31301" checksum="C43AAEBF4CC399DC" modified="2009-10-13" version="1">MSTPGADAAAEQDLDPAEVRQVLTAGELTITGRITNASNATLYGTVALDGVTLNCVHKPVAGERPLWDFPNGTLASREVAAYELSQATGWRIVPPTVMREGPWGPGMCQLWIDTPDEDDHDLLALLPEDFDDDPADQTAAQWRPVLAVELGDGRPAVLAHKADERLRRIAAFDAVVNNADRKGGHLLVGITEPDHVYGIDHGLTFNVEDKLRTLLWGFSSEPLGAEVREVLERLDRDIASGELRGRLGGLLHAGEVAATRERIKELLDTDRIPGPEGRRRPVPWPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9P8</accession>
    <name>C7Q9P8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7391"/>
    <dbReference type="EnsemblBacteria" id="ACU76217">
        <property type="protein sequence ID" value="ACU76217"/>
        <property type="gene ID" value="Caci_7391"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7391"/>
    <dbReference type="HOGENOM" id="CLU_1025615_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="27283" checksum="1B658001EC3440C8" modified="2009-10-13" version="1" precursor="true">MIAAFRYELRRLGSLRATRRVPGGAAVVAAAFGVAAALAVSAGASERAVALLRLAGTLPALVAAVVLGAAASGHERHYEMRYVTLAVVPRRAWLAVAKVTLTAFVSALTGALVALAAALGYALALAWAFAGDRTLIPDGAAADPILQGVAPAAAAATAAGLFGLAVGWLTAWYRASVAVAVAVVALAVPLAAGRLMSGLPAIAKALTDAEDSLRTTPVLSSLLNPRVLTAWPPLKSGMHPIPPTSLAATALLAAVALLGIVVGAMRWQRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9V3</accession>
    <name>C7Q9V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7447</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7447"/>
    <dbReference type="EnsemblBacteria" id="ACU76272">
        <property type="protein sequence ID" value="ACU76272"/>
        <property type="gene ID" value="Caci_7447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7447"/>
    <dbReference type="eggNOG" id="COG4638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026244_3_0_11"/>
    <dbReference type="OMA" id="NFMESYH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="PTHR43756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="7">
        <location>
            <begin position="47"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="44061" checksum="1EEC4147592A0A89" modified="2009-10-13" version="1">MPITEPLSASAPPGPHPQDPPPALAARYYTDPALAEAELRAVFAKTWQLVCHESDLPNPGSRLAAWAAGREVLVVRDAEGGLAAFLNVCRHRGTRLVDAPEPEPKAAEAIRCPYHGWTYKLDGSLVGAPEGRQIPCLDKPKLGLFTVAVESFLGFVFVNVDGTAAPLAQTCAGLAEQVGRYAGAELVPVGRDRIHDLDKAEVQSANWKVAVDNYLEGYHVPVAHPGLMRLLDYQNYRITEAAEDYVLFQTPLRDKPSSNWRERLYQRLTSTMPGLRAEDQRMWRYAVIYPNTLLDFYPDHVLAWTAIPAGQERVAVPGGFYTRRGSSRRTRLARRLNIAIGWITSDEDAELLRRVQHGIRTPGFEPGPLSRREAGVGWFADRIRADMPVRGDGSDGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X9</accession>
    <name>C7Q9X9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7473</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796023.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7473"/>
    <dbReference type="EnsemblBacteria" id="ACU76298">
        <property type="protein sequence ID" value="ACU76298"/>
        <property type="gene ID" value="Caci_7473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7473"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="MGTAFMP"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
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        <location>
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        </location>
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        </location>
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        <location>
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            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
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        <location>
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            <end position="296"/>
        </location>
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        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="16"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="514" mass="52940" checksum="64E3012971F60483" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD7</accession>
    <name>C7QAD7_CATAD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Caci_3530</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3530"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SSF48576"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="38729" checksum="A67033F1C4B6FD8C" modified="2009-10-13" version="1">MPADEITRLFDLPEFRLLPGERRAAWGPELDDHVIDFACRTGLLTTPAARRYYASQRIGTMCAYVVPGALSPRRYEIYGELMTWFFIYDDWAEQLGNHLSPQQVSGVTDVVHTWFAEDERDVVMLDAPLAQSMRGIWAKLQEDTSLEWRRRLLAETDGYLRTAAEEAILVSTGRVNSFGKASELRPTATAAAPVFMMAEHSYGIEIPMDVVRHPLVRKAMRAAAAAIAYGNDIIGLKSDLLRGIRDNLVLSLQQEYGGDLQLNVERAAEHYQRAAGTLTALREDPEAGGREDVAVFFQILEDWVYEGVKWQLRDTDRYSSTVRLTQEENPNQLLALAASSALADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAE3</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ordered locus">Caci_3537</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3537"/>
    <dbReference type="EnsemblBacteria" id="ACU72442">
        <property type="protein sequence ID" value="ACU72442"/>
        <property type="gene ID" value="Caci_3537"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3537"/>
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    <dbReference type="Proteomes" id="UP000000851">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="58" mass="6474" checksum="9440E5C7566E1F53" modified="2009-10-13" version="1">MKLADHVTGSYARKSAQIIANRIIRALVFAALDRRLIPDGDYGDHRVARYQEGCACLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAI4</accession>
    <name>C7QAI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3578"/>
    <dbReference type="EnsemblBacteria" id="ACU72483">
        <property type="protein sequence ID" value="ACU72483"/>
        <property type="gene ID" value="Caci_3578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3578"/>
    <dbReference type="eggNOG" id="ENOG5032VDG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149305_0_0_11"/>
    <dbReference type="OMA" id="IWEHGRR"/>
    <dbReference type="OrthoDB" id="1750764at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="11706" checksum="09BAAD2C3D5A4EF1" modified="2009-10-13" version="1">MSTVVTDEQIQALAATAKPFSLAILQWGPNRTMDGADAIELEHQRRMVSLRADGVIAVLCPVASDTVCGVAVMTLPAEEAAELMAGDPCVRAGMMTCDVHPCHGFPGDALPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW3</accession>
    <name>C7QAW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794165.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5577"/>
    <dbReference type="EnsemblBacteria" id="ACU74436">
        <property type="protein sequence ID" value="ACU74436"/>
        <property type="gene ID" value="Caci_5577"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5577"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080398_1_0_11"/>
    <dbReference type="OMA" id="WEFIFLG"/>
    <dbReference type="OrthoDB" id="1462833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23434" checksum="FD368D6B2E37030B" modified="2009-10-13" version="1">MPNPNLRHIVMVLDRSGSMQAVKNDTEGGLTAFLEAQKEIAGDTRVSLYHFSTTYEPVYENLALADVPEYTLEPRGNTALLDAIGRTITAVKAQIKAMDVEERPGEVVLVILTDGMENSSREYTLPEVKKLIEKRRAKGWQVVFLGADQDAITAAAGMGIGRETSLSYTARMTGQSMSTVARMMARGSASGKYEFTDAERKAARGESEADPKAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW6</accession>
    <name>C7QAW6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794168.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5580"/>
    <dbReference type="EnsemblBacteria" id="ACU74439">
        <property type="protein sequence ID" value="ACU74439"/>
        <property type="gene ID" value="Caci_5580"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5580"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_11"/>
    <dbReference type="OrthoDB" id="1566711at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="37753" checksum="1A7B274523EEABA5" modified="2009-10-13" version="1">MTQKKVLVSGSAGFIGGYVVEELLGRGYKVVGIDNYSKYGPVTKSYDQHPDYEFHEGDVRDTELMVELLSDCDHFIAGAALIGGISYFHTYAYDLLATNERIMASSCDAAIKAHAGGTGRLKKVTYMSSSMVFESATEWPSFEGQERQVPPPLSSYGFQKLAVEYFAKAAWDQYKLPYTIVRPFNCVGVGESRALGDEEILSGNVKLAMSHVVPDLVQKIVKGQDPLHILGTGEQIRHYTYGGDLARGIVTAMEHPDAVNDDFNLSTPHGHSVAELAQAIWGKIKGADVPMTLISDDPFEYDVQRRVPATDKAARVLGFSADTTLDTMLDEVIPWIVSAVENGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB40</accession>
    <name>C7QB40_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796056.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76331">
        <property type="protein sequence ID" value="ACU76331"/>
        <property type="gene ID" value="Caci_7506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7506"/>
    <dbReference type="eggNOG" id="ENOG502ZTBU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1238364_0_0_11"/>
    <dbReference type="OMA" id="EFREMAN"/>
    <dbReference type="OrthoDB" id="1635237at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23942" checksum="597CA0E5DE87C7E8" modified="2009-10-13" version="1">MNAHLPCSDPVCRTVAGVPSSLLPLQLRVVVQPAGAPLGEDPFTADFHPDLVGAVVVKGRQDEPLVLTRHLAATWQVPAARLWDDALAALGVEPLDVRSFPLPGTRAEAYAVTGLGWPGAAHMFRLEQVLGRRLPLGALVMVTDHNSFVALPLESNATLGSASAFWELNERLGRRTPTPLTPLAPRLLWVRGWAVHDLGAGFVNGQFTADLPRELRAALAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW2</accession>
    <name>C7QBW2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxylyase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3679</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792310.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3679"/>
    <dbReference type="EnsemblBacteria" id="ACU72581">
        <property type="protein sequence ID" value="ACU72581"/>
        <property type="gene ID" value="Caci_3679"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3679"/>
    <dbReference type="eggNOG" id="COG0043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023348_5_1_11"/>
    <dbReference type="OMA" id="MSKRAWI"/>
    <dbReference type="OrthoDB" id="1012819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="485" mass="51398" checksum="BBFA65EFC734673A" modified="2009-10-13" version="1">MTGRRLADLRTALAGLDSAPGELVRVREEIPARFGVGARYARWAGTPAAPPTGPGPVVLFEHVRADSGASGPVLMGLYGTRRRAAALLGLEPAEVPFRLLEAVGKPVAPVLLAEDSRPERAARPADLTALPIPVLTDADAGPYLTLGAVLATDPDTGVRNLSVHRMCVQGPDTLTIWMVPGRDLERAYNAALARGESLPVAIHLGVPPAVLLASCCPSSLVPPEVDEIAVAGAIGGAPVELMPCGSIDAECIAHAEYVIEGEILDKVVPENPAGPFATPEFLGYRGRAHPALPVIRVSAITARPGAILQSVSGPGLEQSVLLGYGMEAAVLAFLRERGAPIVSALCHTAGGGQLMLVLRWRKRSGEDDALVRDCCEAVLETFRMVKTVLAVDEDVDPESDQDLWWAMATRLQADRDITILPDREGFALDPSQSTVYSPNLSGDGRTAKAVFDCTVPFALRDRFTRAEFTPEPAGGARRQAARRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC95</accession>
    <name>C7QC95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794272.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5685"/>
    <dbReference type="EnsemblBacteria" id="ACU74543">
        <property type="protein sequence ID" value="ACU74543"/>
        <property type="gene ID" value="Caci_5685"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5685"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039929_3_0_11"/>
    <dbReference type="OMA" id="NMGWFLI"/>
    <dbReference type="OrthoDB" id="1529037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="33389" checksum="EBA59C83298AE665" modified="2009-10-13" version="1">MYITQHFWELLFQGIRLGSLYALIAIGYTMVYGVLQLINFAHSEVFMSGALGGVFMLTALVGTNGDVPSGFSAFEYTALALIAGAAVGAAIAFSLEQVAYRPLRKRHAPKLVYLITAIGASIFLYNLAGKLFGRNNLQVPESFHSGKVFVLPGTGPAGPRTVKTLDVMIIAIAVIMMVLLDLLINRTKLGAGIRSVAQDSETAQLMGVDVSKVISRTFIIGGLLAGVGGVLYAMFHAVNYTMGFVPGIKAFTAAVLGGIGNVRGAMLGGLLLGIVETFSQGIFSLEWVDVVSFVVLVAVLLIRPTGILGERTGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCG2</accession>
    <name>C7QCG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RDD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7601</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7601"/>
    <dbReference type="EnsemblBacteria" id="ACU76425">
        <property type="protein sequence ID" value="ACU76425"/>
        <property type="gene ID" value="Caci_7601"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7601"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054176_0_0_11"/>
    <dbReference type="OMA" id="WMLTGGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="7">
        <location>
            <begin position="17"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="34577" checksum="E7CC60025A8ED2F2" modified="2009-10-13" version="1">MSDLVIGEGVALDLRLAKLPSRALARLLDLLVQAGLLGVLAAVLGIVAAAGTVDDAVMAGLMIVMTVAVVVGYTALMETVSRGRTLGKMALGLRVVRTDGGPVRFRHALVRALTGIFDLYITVGVLAVVTSFCSKQGRRTGDWLAGTVVVRDRAPDVGVSPMGMAALAMPYPLLGWAQQLDLSALPDDVALSARQFLTRMHEMRPDVAARMAHELASEVMRYVVLPAAGTPPWAYLAAITAERRVRQMRTAEAAQRAAWEQAQAQTPAYAGAPAPAAWQGSAEGAHLPAMPQHQSQPQSQPPVQDRIPESAAEPRGETDGDGFKPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH7</accession>
    <name>C7QCH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796165.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7616"/>
    <dbReference type="EnsemblBacteria" id="ACU76440">
        <property type="protein sequence ID" value="ACU76440"/>
        <property type="gene ID" value="Caci_7616"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7616"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_0_2_11"/>
    <dbReference type="OMA" id="PFLTHQL"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="364" mass="37581" checksum="34B28033B28E14C1" modified="2009-10-13" version="1">MTEAILLVGGKGTRLRPLTVNTPKPMLPVAGVPFLTHQLVRAKDAGVHRVVFATAYKAEVFEQYFGDGSDLGLELVYVTEEVPLDTAGAIRNVAGKLTSAPDEPVLVFNGDILSGVDIAGLVTAHREHGADVTLHLSRVTDPRPFGLVPTDAEGWVTAFLEKPQRPEDIVTDQINAGCYVFQRSRIDEIPAGRRVSVERETFPGLLASGAKVLGVVEQSYWLDLGTPAAFAKGSADLVMGVVTSSAVPSPAERGSAESLVLAGARIAEDAVADAGTTVGSGAVIESGAHVSSSVLQSGAVIGAGAKVTSSIIGAGARIGARTVLDGVVIGDGAVLGADNELRAGARVWCGAVLPDKAVRFSSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDC0</accession>
    <name>C7QDC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792442.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3812"/>
    <dbReference type="EnsemblBacteria" id="ACU72713">
        <property type="protein sequence ID" value="ACU72713"/>
        <property type="gene ID" value="Caci_3812"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3812"/>
    <dbReference type="eggNOG" id="ENOG5033G9Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2328617_0_0_11"/>
    <dbReference type="OrthoDB" id="2005618at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10148" checksum="5952EBCF4F565C5B" modified="2009-10-13" version="1">MWQTIALGFLGGVLAGNALPHFLRGITKRRYPSAFGNGPVPNLVAGWAGLVIGTVLLATAHLTRHPWPALAGVSVGVLLIGLFHAGPGAFGREEPQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF9</accession>
    <name>C7QDF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU72752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3858"/>
    <dbReference type="EnsemblBacteria" id="ACU72752">
        <property type="protein sequence ID" value="ACU72752"/>
        <property type="gene ID" value="Caci_3858"/>
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    <dbReference type="KEGG" id="cai:Caci_3858"/>
    <dbReference type="eggNOG" id="COG1293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_408632_0_0_11"/>
    <dbReference type="OMA" id="NLWLIDE"/>
    <dbReference type="OrthoDB" id="358981at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="680" mass="74906" checksum="D3F954A5BDAE9129" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDL3</accession>
    <name>C7QDL3_CATAD</name>
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        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_5779</name>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="gene ID" value="Caci_5779"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
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    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
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        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF21"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="12">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
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        <location>
            <begin position="279"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
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            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="468" mass="49600" checksum="500DDE3BE78E71CA" modified="2009-10-13" version="1" precursor="true">MLTLLGLLAIAVLTAATGYFVAQEFAYIAADRGRLRQLAEDGDAAAERAFEVTGRLSFMLSGAQLGITVTALLVGYVAQPLLGSGLADLLGFTGWSHDARLSLSVVVALAVATVVQMVVGELLPKNLAIAKPIEAAKALGGSTLLYLKVVGPVIRLFDGAAVRLVRAVGIEPVEELPQGASEEDLQHIISESHTQGLLDTELSELLDRALDFRGLTAGQAMTPRVKVHTVSAEAPVSLVVEMLITGNARFPVTGHDIDDLIGVAGLTEVLAVPAALRATTPVRDACAPALLVPEHLPLPELLERLRSEHRQLACVIDEFGGFAGVVTLEDVTEELVGDIWDEDDLDDEVVRRQPDGAWSVPARMRIDEAADATGIPLPEGEHYTTVSGLVLDRLGRTARIGDEVELAVRAPYTQDGPGMLSVLIHIAAVSRQVPATVLITMDTEDHAEDSEHSADPEHSAAPDAREAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDN7</accession>
    <name>C7QDN7_CATAD</name>
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        <submittedName>
            <fullName evidence="7">C4-dicarboxylate transporter/malic acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5803</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <dbReference type="DOI" id="10.4056/sigs.17259"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OMA" id="LSPPYWI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
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        <property type="entry name" value="SLAC1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
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        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
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        <location>
            <begin position="388"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
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        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU74661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="429" mass="44006" checksum="A41B659FC25416EB" modified="2009-10-13" version="1">MISRSSRPEQALNARTKRPTDSDSPAEAHGSASPTTASAATSPDRVSRPPDTSDPTGATGSSSPTTASAASSPASPGNSAGATAASTAASPTPTPASTSTNPLANVLSWFAAQPPAAGSAVMATGIVSIGLRQVGAQVLSVVALVLAVLLWLALADDFGRRLVWQRGRWVSEAQTPPALTAVAATTVLGVRFTLAGWLAVAVGLLVVAAVLWPLLLWAVVRRLRPHMPGAVFLICVATQGLVALGAALAVALPARWLLGPALVLFVFGLVLYVDALAHFDFGAVRSGAGDHWVAGGALAISALANAKLTEAEGGSGGLHSTLRVTALVLLALAWVWYAVLAASEIRWPRLRYDVRRWATIFPMGMTGAATDEVAKASGWTWLTTPGHVLVWIAAAAWLVVFAGLLREAAKTTSQSGASQSGTSQPHPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE03</accession>
    <name>C7QE03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796316.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7767"/>
    <dbReference type="EnsemblBacteria" id="ACU76591">
        <property type="protein sequence ID" value="ACU76591"/>
        <property type="gene ID" value="Caci_7767"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7767"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_11"/>
    <dbReference type="OMA" id="HSLAGFH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31213" checksum="EEA4D883EEDD3CCE" modified="2009-10-13" version="1">MRFVDDRGTLLHVVRDGEHGPAVLFVQGLAGAWFEWNPVVPLLAGDHRLVRFDRPGLGWSQQEFGDDGRPLPQTLAGEAERLGRVLDAVGVAPEEKVFVVAHSYGAFHAEAFARLHPERIAGVVFVDGSAEPDITPAPGGPGRVLGQAFVRGTKALGLNQVLGPAVRRLVYQAASTTHRDPDRELGRAVYRSSRVAAAVVNELWSYRPSAVELLELRCERPFPEVLVQVLVGAAGAAQDAHARRWVERQREFAGLFPGAEVVELPDAKHLIAADRPDAVATAVRSLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE32</accession>
    <name>C7QE32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796345.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7796"/>
    <dbReference type="EnsemblBacteria" id="ACU76620">
        <property type="protein sequence ID" value="ACU76620"/>
        <property type="gene ID" value="Caci_7796"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7796"/>
    <dbReference type="HOGENOM" id="CLU_1755554_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="15365" checksum="3C92BAEB34A47ECB" modified="2009-10-13" version="1">MRIMTGTAVDNRVAMTPAPVYRALEAFAADCRRVSGQECFGSAAAAWQVESVSGTGLAGAAGFLGLVALGEGLLERHGYVGQLGQERPRPVFQLVPAPGTGRILADEQAPIDGSGTSERDDDSNDSSKGDNGSKPMTPWDFRTSGPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE81</accession>
    <name>C7QE81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796394.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7845"/>
    <dbReference type="EnsemblBacteria" id="ACU76669">
        <property type="protein sequence ID" value="ACU76669"/>
        <property type="gene ID" value="Caci_7845"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7845"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1048420_0_0_11"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="3">
        <location>
            <begin position="141"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="28115" checksum="13CE024BA8A62D2F" modified="2009-10-13" version="1">MTDAQITDTGVETGTGPGTGTDAQTGPATATGGQPGSRWHWLRQPEVLIPLILLGVFLVLWALVLARPTFLTQFDLWVRNRVQSVAHATDGKTHWPVFKGIADLGGGVTVHGVPFQIQVPVVAMALVGLSAAIVRRSRRPLLAMAAGYAALLVVLFLKAIGDRPGPSMAGQAMSGGLGYFPSGHTGNTMLCYGTSTLILAFVFTGHRMRIVLATAMTLWALAVGFSLVWMDYHWVSDVLGSYALCGAALFGVARVLGFRIRAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEV2</accession>
    <name>C7QEV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator TrmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3997</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3997"/>
    <dbReference type="EnsemblBacteria" id="ACU72872">
        <property type="protein sequence ID" value="ACU72872"/>
        <property type="gene ID" value="Caci_3997"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3997"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_992849_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981587" evidence="2">
        <location>
            <begin position="26"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="HTH marR-type" evidence="3">
        <location>
            <begin position="169"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="30106" checksum="74D5EB41C20DE357" modified="2009-10-13" version="1">MAVLICGLRGSTPCGAPRSSSPVQASELGFCAMVPEELKPLDGASALWSRRGPAPRTAHLAPRTAHRAPRTAHRAPRTAHRAPRTAHRAPRTGHDRRERATHRGNPHEVSRRQLTSAFRLPPTYLPPGSKSALAVGNYCNLIHEPTCSIYDGGVTSLDARTWALLTGHGHVLVAVTRNPQARVRELSEEAGLSQRATQSILADLEVAGYIIRTRTGRRTVYTVDLDHPFRHRAQDGLRVGPLLLWLASTSGEFPSAVSAELGEPGLVAAPGLTLAGEPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF64</accession>
    <name>C7QF64_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5964"/>
    <dbReference type="EnsemblBacteria" id="ACU74822">
        <property type="protein sequence ID" value="ACU74822"/>
        <property type="gene ID" value="Caci_5964"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5964"/>
    <dbReference type="eggNOG" id="ENOG5032NYW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107608_0_0_11"/>
    <dbReference type="OMA" id="EPYDAFD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22541" checksum="5D3FAA5EDD4B45E0" modified="2009-10-13" version="1">MTIEDDDDLALPAALAAIAAIGFPQEAGEDEPREDDADNNDTDNNDDDTDDDEGETLAHPPVDFELFEEFLDTDDTDDWFQGWTANPDADAGQFRVFGQTADGGYAAFWLVREDAPLAEQPIVFLGADGETGVVACDLPSFLWLIADGSGPYEAVEHPTRRSTPHPEFTAIAEKHAGTERMTARQVVAAARDEFPDFEDTMVELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFA3</accession>
    <name>C7QFA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein ArsR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7857"/>
    <dbReference type="EnsemblBacteria" id="ACU76680">
        <property type="protein sequence ID" value="ACU76680"/>
        <property type="gene ID" value="Caci_7857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7857"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_1_0_11"/>
    <dbReference type="OMA" id="PSFFCRR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045981">
        <property type="entry name" value="DUF5937"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19361">
        <property type="entry name" value="DUF5937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="255"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="35939" checksum="F3F2F58CBE8329A9" modified="2009-10-13" version="1">MVGIPMTSADLAHIGFETSPLVNLVRGLDQLGSTRPLRSAHRRWLAGALRQIPERCRPLMELLNAIPNYAPAFLIPDLPPTGRLHRGLDEELDALRAVRDTELALDFTIFDTWERRPSRAYDALRDRGDRLIPVLTDAMHALYTACLAEDWPDIRRTLDADIGRRARQMAIDGPGAVLNDLHPKLSWEPEKLSLAVSKVPDWRYDLRGDGLTFTPSVFGHYVGSLIAPGRRSIMAYPVSDLDASAALSPDGSPGDGLASLIGRARAAALRAIGDDPTTGELAVRLGVKAPTASAHAAALRSAGLVVTERTGRSVRHRLTGLGAELIAANRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD5</accession>
    <name>C7QFD5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796437.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7889"/>
    <dbReference type="EnsemblBacteria" id="ACU76712">
        <property type="protein sequence ID" value="ACU76712"/>
        <property type="gene ID" value="Caci_7889"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7889"/>
    <dbReference type="eggNOG" id="COG2135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035990_6_2_11"/>
    <dbReference type="OMA" id="WQLTATI"/>
    <dbReference type="OrthoDB" id="1718602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="28261" checksum="0373D1D34E025A4C" modified="2009-10-13" version="1">MCGRYVLRTDPSQLADQLGIGQPEMFEQVAETFEPNYNVAPTDPVVAAIERHPRDAEPGSEAVRKLREVRWGLVPSWAKDRKIGQKMFNARIETVTEKASFKRAFMKRRCIIPADGYYEWYKPAGPKPVKQPFFIHDASGDALAFAGLYELWRDPEIEDKEDPAAWLWSATILTTASVGGLHRIHDRMPVIVPRAHFDAWLDPDYGSGEGDADALLGLLDAGRDPHLDTFPVSPAVNSVRNNGPELVVPLEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU1</accession>
    <name>C7QFU1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786211.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1998"/>
    <dbReference type="EnsemblBacteria" id="ACU70918">
        <property type="protein sequence ID" value="ACU70918"/>
        <property type="gene ID" value="Caci_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1998"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_1_11"/>
    <dbReference type="OMA" id="IELQEMM"/>
    <dbReference type="OrthoDB" id="1860081at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="13876" checksum="3C07B163190318DF" modified="2009-10-13" version="1">MIVELDDTSPVPPYEQIRAQVAAMIGSGALPPGTRLPPIRQLAGDLGLAVNTVARAYRELEAGKLVASRVRTGTVVAPRTPHAPDDRTAADTRRLLTEAVRSFAATTRRLGIADHDALAAITAELRGEASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU5</accession>
    <name>C7QFU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786215.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2002"/>
    <dbReference type="EnsemblBacteria" id="ACU70922">
        <property type="protein sequence ID" value="ACU70922"/>
        <property type="gene ID" value="Caci_2002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2002"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324180_0_0_11"/>
    <dbReference type="OMA" id="QWSERRK"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24477" checksum="48F6B3299E7714A9" modified="2009-10-13" version="1">MKEDSENAGSVAPVAPVAPAGYRRSAGTPRAQARRRDLLDAVTDDLAAHGLVDFSLRRAAKAAGTTHKVLLYHFEGAEDLLREAVELLRERRLTSSMAAAFAPDQEQTLAGRVRAVWPVLTGSGEGQRALDQALGLAMYDPGRHAALAVDAAGHFLPALRDMCPPQWSERRKDEVAELVFAALRGFLVQRRTGGSEGGGGSDGGGDGNGVGDGDEPGFAALLRMLEHEEAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU9</accession>
    <name>C7QFU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2006"/>
    <dbReference type="EnsemblBacteria" id="ACU70926">
        <property type="protein sequence ID" value="ACU70926"/>
        <property type="gene ID" value="Caci_2006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2006"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OMA" id="YPHAADE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="19982" checksum="4CAD6A0C74221ED1" modified="2009-10-13" version="1">MTIVQTTAKILVAGGFGVGKTTLVGSVSEIEPLTTEAEMTSVGRGIDDTVGVPGKTATTVAFDFGRLTLADDLILYLFGTPGQERFWFLWEELARGAVGAVVLADVRRLADAFAAIDFFEHRGMPHVVAVNQFDGARSYSQEALREALAIPSSTPVMICDARDRTSTVTVLLALVEHAVKWHAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG40</accession>
    <name>C7QG40_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786310.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2098"/>
    <dbReference type="EnsemblBacteria" id="ACU71017">
        <property type="protein sequence ID" value="ACU71017"/>
        <property type="gene ID" value="Caci_2098"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2098"/>
    <dbReference type="eggNOG" id="COG3369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043311_0_0_11"/>
    <dbReference type="OMA" id="TALYSIK"/>
    <dbReference type="OrthoDB" id="935353at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026820">
        <property type="entry name" value="VioB/RebD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12902">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like" evidence="1">
        <location>
            <begin position="22"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="38984" checksum="2ACECF7F57BF80E2" modified="2009-10-13" version="1">MDYVDTRAAHTIDTLDDLRRHLQWAIELEHATIPPYMCALYSLDPERNPEAAQVVSTVLTEEMLHLALAANLLNAVGGTPKLDAPQLLPTYPHPLPHSDGSVQIHLVPFGPEALDLFLQIEQPATADAPPQSDRYRTIGQFYAAIEAGLRTLCEELTEEAVFHGDPRRQLGDMHLPGGGGQVIPVHDLKSALAALAEIIEQGEGAARTDVWDGDVDVFHPDRDEVAHYYRFHELRTGRRYQRGDTPQSGPTGDPITVDFDAVLPMRRDACTTDHPEDSPIRKAQQEFDQTYCLLLYLLEQAFNGDPSQLKDSVGVMYQLRAQALKLMKMPDGDDGTTAGLTFEYVLPELRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ5</accession>
    <name>C7QGJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794604.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6018"/>
    <dbReference type="EnsemblBacteria" id="ACU74875">
        <property type="protein sequence ID" value="ACU74875"/>
        <property type="gene ID" value="Caci_6018"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6018"/>
    <dbReference type="eggNOG" id="ENOG5033ZGD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161420_0_0_11"/>
    <dbReference type="OMA" id="DPEHFFD"/>
    <dbReference type="OrthoDB" id="1899562at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12521" checksum="844380BD15F437FA" modified="2009-10-13" version="1">MPSKPEPKKRPLHLIGEPAAPVPIDTESFFGLDSIEDPLQLLSRSTELADAFRASAGRAEHYQAVAAARLTDPRRFDRMPVADLALLTGWTEEYATKMAEFGRTLLDKGAPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL8</accession>
    <name>C7QGL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BFD domain protein (2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794627.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6041"/>
    <dbReference type="EnsemblBacteria" id="ACU74898">
        <property type="protein sequence ID" value="ACU74898"/>
        <property type="gene ID" value="Caci_6041"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6041"/>
    <dbReference type="eggNOG" id="COG1251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2341621_0_0_11"/>
    <dbReference type="OMA" id="YVCMCHA"/>
    <dbReference type="OrthoDB" id="1969696at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer2_BFD" evidence="1">
        <location>
            <begin position="4"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="9702" checksum="FF1F14FB3740A86C" modified="2009-10-13" version="1">MYACICHAVTTAEVDAAVALGATSVKHVRKATGAGSACGTCVKRLSCLLAAARVADSAPPEVMPEAERLPAREPASVPAAAIFEHAPHCPAAVPALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM7</accession>
    <name>C7QGM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794636.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6050"/>
    <dbReference type="EnsemblBacteria" id="ACU74907">
        <property type="protein sequence ID" value="ACU74907"/>
        <property type="gene ID" value="Caci_6050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6050"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="RYAWAMA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="311"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="47047" checksum="B6761A64A81BA12B" modified="2009-10-13" version="1">MTDQPPQPPSRPWLAWLWVERSTVGLPLIVLVIDVFGTWGAYGHWHNQGGSTQVDVRPLDWFAWLLVVAGPIALWHRRKAPRVAFAVCLGATLLYLLMGYATGPIYLNALLAVIVIGGTGYRREVWAGSLLFAIGMIFVPTHAHVGEKRNSPADILFTAGWLLALLMLAELFGLLRQRALEAQKARDQEARAREQESRRQASEERLEIARELHDVLAHSISLIAVQANVALEVMDRRPEQARIALSAIKDASRSALGEVRSVLTVLRGDRAAPRDPAPDLGRLGHLVELAEAAGLKVALSVVGDLEAVPLAVSQAGYRIIQESLTNVVRHAAAGRATILVEAAGGLHLRIADDGRGCPLGEPGAGGNGLPGMRERATAFGGTLTAGPQSGGGFRVDAHIPFGALLGNAGSNADGNADADAVIVTDTAPTLTPTAEDHAEEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU7</accession>
    <name>C7QGU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796522.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7974"/>
    <dbReference type="EnsemblBacteria" id="ACU76797">
        <property type="protein sequence ID" value="ACU76797"/>
        <property type="gene ID" value="Caci_7974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7974"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069623_0_0_11"/>
    <dbReference type="OMA" id="WAELHTS"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="140"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="28038" checksum="B7C725CB872C2E10" modified="2009-10-13" version="1">MITSENTSNLPGWIDLGSPDAGASAEFYGQVFGWTAENLMPESADGPGYWSLKKDGKQVAGLGGLTDPSARPDWMTYIRVADANATVAAAESNGAKVRVPVTEVPGEGSMAQLTDPSGAEFALWQSGGTTGFEACCVEDTMLWAELWTRDPAAAKSFYPALFGWQVEPYMEGAPESGGYDMWTMQPGDPLAAFGGIMTITDQVPIQDEKWIPYFMVADADRTVERVSAAGGAVLIPAADAPPGRLAALADQFGARFNILQPAPMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHE9</accession>
    <name>C7QHE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0133"/>
    <dbReference type="EnsemblBacteria" id="ACU69088">
        <property type="protein sequence ID" value="ACU69088"/>
        <property type="gene ID" value="Caci_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0133"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050006_6_3_11"/>
    <dbReference type="OMA" id="WEYEKRW"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27586" checksum="40EEE37CC29EF566" modified="2009-10-13" version="1" precursor="true">MSWPLAFSTLGCSGLPLADVVELARSTGWLGLELRAADDEPVHVGLSPEERVAARALLESGGVTVLAVASYVKVARGEIGDDECVADALAHADLARDLGAPFVRVFPGAEEPGADADARAVRRLNAIAERLPEGVAVLLETHDSHPQGVDIARVLSQVSGDVGTIWDVMHPWRTGEPISVTKDVLAPYLRHVQVKDVLSPTERTPLPLGDGTIPLAEFYAALRELGYQGWMSLEWESKWHPEAVPLADALKVKPDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG7</accession>
    <name>C7QHG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YcfA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784401.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0151"/>
    <dbReference type="EnsemblBacteria" id="ACU69106">
        <property type="protein sequence ID" value="ACU69106"/>
        <property type="gene ID" value="Caci_0151"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0151"/>
    <dbReference type="HOGENOM" id="CLU_164851_7_0_11"/>
    <dbReference type="OrthoDB" id="2053618at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038570">
        <property type="entry name" value="HicA_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="62" mass="6949" checksum="1AD59179A750DC71" modified="2009-10-13" version="1">MKRRDLLKALSDIAAEASVDFELVRHGGSHDIYRVGALHLTIPRHTEISELLAKKILKEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHH2</accession>
    <name>C7QHH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bilirubin oxidase</fullName>
            <ecNumber evidence="6">1.3.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.3.5" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784406.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0156"/>
    <dbReference type="EnsemblBacteria" id="ACU69111">
        <property type="protein sequence ID" value="ACU69111"/>
        <property type="gene ID" value="Caci_0156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0156"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009100_2_2_11"/>
    <dbReference type="OMA" id="PYSGRYV"/>
    <dbReference type="OrthoDB" id="971126at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047705">
        <property type="term" value="F:bilirubin oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981644" evidence="3">
        <location>
            <begin position="32"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="167"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="417"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="528" mass="56794" checksum="027AE151882B3FE0" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHH4</accession>
    <name>C7QHH4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative phenylalanine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pat</name>
        <name evidence="5" type="ordered locus">Caci_0158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the transamination reaction in phenylalanine biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784408.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0158"/>
    <dbReference type="EnsemblBacteria" id="ACU69113">
        <property type="protein sequence ID" value="ACU69113"/>
        <property type="gene ID" value="Caci_0158"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0158"/>
    <dbReference type="eggNOG" id="COG0079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_3_11"/>
    <dbReference type="OMA" id="YPDMACT"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01513">
        <property type="entry name" value="Phe_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024892">
        <property type="entry name" value="Pat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="31"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="356" mass="38598" checksum="773E4826F0A6D5DE" modified="2009-10-13" version="1">MADDVQTPKLREALRGIPAYKAGKNPDASAFKLSSNENPYPPLPGVLEAVQKSAENFNRYPDMGCSALSSEIAERFGVPVEHVATGTGSVGVAQQLLQATSGPGDEVIYAWRSFEAYPIITQISGATSVRVPLTPEEHHDLDAMAAAVTDRTRLIFVCNPNNPTGVAISEDALVRFLDRVPSDVLVVIDEAYREFVRDDSIPDGVDLYRDRPNVAVLRTFSKAYGLAGLRVGFAIAHEPVAAALRQTAVPFGVNSLAQVAAIESLRAEKLLLERCEALVQERTRVTEALREQGWTVPESQANFIWLRLGERTAEFAAKAEAAGIVVRPFAGEGARITVGEVEANDILLRVTAEFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHX8</accession>
    <name>C7QHX8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4159</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792752.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4159"/>
    <dbReference type="EnsemblBacteria" id="ACU73023">
        <property type="protein sequence ID" value="ACU73023"/>
        <property type="gene ID" value="Caci_4159"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4159"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="FENICVP"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25813" checksum="7CE11F6CD5FCDCDF" modified="2009-10-13" version="1" precursor="true">MTGNTILELRRVTRTHGKGAAEVHALRGVDLVVRAGELVAVMGPSGSGKSTLLSLAGGLDSPTGGDVLVEDTPLSSQSKPQLAAIRRRSVGYVFQDYNLIPALTAAENVALPRELDGISARKARVEALAALEEVGLQAESDRFPDEMSGGQQQRVAIARALIGDRRLILTDEPTGALDTETGEAVLRLLRKRCDEGAAGVLVTHEARHAAWADRIVFIRDGLIVDESAPSQRAEDLLIGEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI18</accession>
    <name>C7QI18_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4199"/>
    <dbReference type="EnsemblBacteria" id="ACU73063">
        <property type="protein sequence ID" value="ACU73063"/>
        <property type="gene ID" value="Caci_4199"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4199"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_6_0_11"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="178"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="43268" checksum="1197167D94342BC6" modified="2009-10-13" version="1">MLDEALKLYFDLHQYPELAGAEKRTAARFADRLRRCGLTVRTGVGGHGVVGVLHNGAGPAVLLRAELDALPIAEQTGLAYAADEALGAMHACGHDAHLACLAGTAELLARHRSSWRGTLIVLGQPAEEELSGAAAMLADGLYERCGRPDVALAQHLTPLPAGWVAHAPGAVTAASRQLELRVHGRGGHAGLRQFAVDPVPVAAAIVLDAAGIGARLPAAVTVGTICGGSRPNVIPEEVTLGISVRAPTTAVLQEAVADLVRIAQQHARRAGCPRLPELSVLSASPAGVNDPVAGRIVREAHLPRFGSGHVLTLPPSLATDDFPLLTLPDSADPVPSVYWMVGATAPEVWSRAAGTSLVEKAANVPANHSAAFAPDPVRTLRTGIAAMTEAALAFLTRQPSPTLTTVSDDVPTSEGISAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE7</accession>
    <name>C7QIE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794753.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6170"/>
    <dbReference type="EnsemblBacteria" id="ACU75024">
        <property type="protein sequence ID" value="ACU75024"/>
        <property type="gene ID" value="Caci_6170"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6170"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_0_11"/>
    <dbReference type="OMA" id="SEAYYMA"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="35776" checksum="E68D9E5EE5E2BCB8" modified="2009-10-13" version="1">MTATLDGAAQSTEISLAQAVNRALRDAMTADEKVVVFGEDVGVLGGVFRVTDGLTRDFGEQRCFDTPLAEAGIMGTAIGMAMYGFRPVVEMQFDAFSYPAFEQIASHLAKMRNRTRGALPLPVVVRVPYGGGIGGVEHHSDSSEGYFAATPGLHVVTPATVSDAYTLLRAAIESDDPVIFMEPKRLYWSKDQLSTTGPAIGEAAVRRQGADATLIAYGPTVQTALEAAEAGAAEGYDLEVVDLRSIVPFDDATVTASVRKTGRAVVIHEAAGFGGTGAEIAARVSERCFHWLEAPVRRVTGFDIPYPPPKLERHHLPSVDRVLDAVASLQWEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ44</accession>
    <name>C7QJ44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69186">
        <property type="protein sequence ID" value="ACU69186"/>
        <property type="gene ID" value="Caci_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0233"/>
    <dbReference type="HOGENOM" id="CLU_3059779_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="53" mass="6032" checksum="DB3D6D03D2B2EBDE" modified="2009-10-13" version="1">MVLMSSRVGRQVANDVDFERWQRQAREIDYRAVSGGHWSIVDESTADISMFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ53</accession>
    <name>C7QJ53_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784490.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0242"/>
    <dbReference type="EnsemblBacteria" id="ACU69195">
        <property type="protein sequence ID" value="ACU69195"/>
        <property type="gene ID" value="Caci_0242"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0242"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_39_2_11"/>
    <dbReference type="OMA" id="YRRWPDV"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="22898" checksum="3077A211E8869A94" modified="2009-10-13" version="1">MDASRHSDDKILDAAQSALLDLGLRNTTLAEVARRAGASRMTLYRRYPDIDALLTEVLGRQLIRVVRRNAGLQELAGGGRSARDLLVTGTVEVVRAFHGDLLMHKILESDAEFLLPYMTREFGPLQHYALDLLSMRLEQGHEDTSIRHGSVALQARTVLLTAQSFVISARAAGSVPMDRLLEELREMLDAYLRPSADGAQAPDPEPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ76</accession>
    <name>C7QJ76_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0265"/>
    <dbReference type="EnsemblBacteria" id="ACU69218">
        <property type="protein sequence ID" value="ACU69218"/>
        <property type="gene ID" value="Caci_0265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0265"/>
    <dbReference type="eggNOG" id="ENOG502ZITF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131550_1_3_11"/>
    <dbReference type="OMA" id="VEWLAFL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="7102" checksum="45A0533851C6B427" modified="2009-10-13" version="1">MIGNDGLQWRKAAASSGNGSCVELAPGLAGSVYMRDSKDPQGPVLTFTRKEIAAFLEGARGGEFDDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJN0</accession>
    <name>C7QJN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2335"/>
    <dbReference type="EnsemblBacteria" id="ACU71253">
        <property type="protein sequence ID" value="ACU71253"/>
        <property type="gene ID" value="Caci_2335"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2335"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_1_1_11"/>
    <dbReference type="OMA" id="YNPGHVM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="5">
        <location>
            <begin position="55"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="149"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20799" checksum="D9C0A3AF823B6299" modified="2009-10-13" version="1">MTMPDSPDDPNQAAGLEAQDGAGEPDGFRRLWTPHRMAYIKGENKPTGPEAGEDPFCRIPSLSDEDGLVVARGELVYAVLNLYPYNGGHLMVVPYRHVADYTDLTVPETAELADFTKRAMRAVRAASGAQGFNIGMNQGDVAGAGIAAHLHQHVVPRWGGDTNFMPVVGHTKVLPQLLGETRKLLADEWPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX0</accession>
    <name>C7QJX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792937.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4344"/>
    <dbReference type="EnsemblBacteria" id="ACU73208">
        <property type="protein sequence ID" value="ACU73208"/>
        <property type="gene ID" value="Caci_4344"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4344"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_0_11"/>
    <dbReference type="OMA" id="YANYAGH"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="48578" checksum="315F3D77F47BADE4" modified="2009-10-13" version="1">MRELSISLSQVKGRVVWPSDPDFDEIRRPFLGGWDRSPAVIVRVADAADVAIVLAAARTTGLPLAVRSGGHSLHCLVDDGIVLDLHDLRAVDIDVANRTAWAGPGATAAEYTAAAEAHGLMTGFGDTGSVGLGGLVTGGGLGYLIRAFGLTVDDLLAAEIVTADGRHLLVDAEHHPDLFWGIRGGGGNFGVVTRLKLRLHKLSAVYGGLLVLPATAELLADYMRLSLEAPEELSSILNVMPAPPMPMVPEELWGQMVAMAMLVYVGGPEDGEKAVAPFRALAEPLMDMVAPMPYSAVYMMEDPDYHPMALSRTTFLDEFDADKAEQILARLRMPTSAMPACQLRALGGAMARVPADATAFAHRDRAFLATAAVVYLDAAEEETHKAWAVEFGTMMRGWSGGGSYVNFLYDDEMDRIHEAYPPATWERLVRIKQQYDPENLFRGNANIPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY3</accession>
    <name>C7QJY3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4357"/>
    <dbReference type="EnsemblBacteria" id="ACU73221">
        <property type="protein sequence ID" value="ACU73221"/>
        <property type="gene ID" value="Caci_4357"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4357"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122336_0_0_11"/>
    <dbReference type="OMA" id="WRATHET"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="54"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20678" checksum="A02D8B53F9FFBECB" modified="2009-10-13" version="1">MPPADQPFADHSADQPAADHPADQPFDDPTDTSLWRPLHALVASIDAAISQVYADAAIKGVKPTWVRELLRLYRTGPMTITELAEAVDRTHSALSQKVAAMKAAGLVRTTPGPDARTKHVDLTPKARHLAPRLAAEWRATEATLADLEAEIPYPITQAVTDIEQALARKSFHDRITERLREDPAWRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK35</accession>
    <name>C7QK35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6255"/>
    <dbReference type="EnsemblBacteria" id="ACU75109">
        <property type="protein sequence ID" value="ACU75109"/>
        <property type="gene ID" value="Caci_6255"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6255"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060326_0_0_11"/>
    <dbReference type="OMA" id="WWWTQHL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="32686" checksum="8277AA1AB41C005B" modified="2009-10-13" version="1">MTAEDDAPSPTPSPEGGGGRGLRSRLTRLIAAARARRGELEERSPKLAEVLRVALAPETIDRCFAVAAQIFITAVPMALAVLAFLPHQLRDRVRESLSAQLGIEGSAAQSVNAFFNGQDELRDAIGVAGLVLALFSATSLTRRLQRVYERSWMLPPGRMKSSAVRWLAWILVWIAVLSAQGPLRAGSGWWRFWGWTASAAMSVALWWWTPHLLLLRRVGWRTLLPTALLTGLAQTAIGIGSRFVMPRVTGRSVAEYGPFGLVLSLMSWLLVVAGVIVLGAGIGRVLAGDAADPPKQAVSPPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKG2</accession>
    <name>C7QKG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796786.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8238"/>
    <dbReference type="EnsemblBacteria" id="ACU77061">
        <property type="protein sequence ID" value="ACU77061"/>
        <property type="gene ID" value="Caci_8238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8238"/>
    <dbReference type="eggNOG" id="COG4448">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062004_0_0_11"/>
    <dbReference type="OMA" id="DDCGAPT"/>
    <dbReference type="OrthoDB" id="1434447at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="PTHR42110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="33082" checksum="0DD548FE9248BCD6" modified="2009-10-13" version="1">MTAQGVVPLAEIVRSGFTEGWHDGRLVALAADGSVEFAYGDVEAVMMPRSSNKPMQAVAMLENGLDLTGELLALAAASHAGEPFHLEGVRKILAGAGLDEQALACPADWPLAEQAKLAMVRAGGDRQRVTMNCSGKHAAMLATCVVNHWPITDYLAPDHPMQRASRAAVERLSGEPVRHDAVDGCGAPLYGISLVGLARAFRACVLAAPATPERRVADAMRAHPEYVSGTDRIDTDLMAGVPGLLAKGGAEGVQAVALPDGRAIAVKVGDGDHERRAVGPVLVAALRRLGVEAPVLSRYAESPLLGGGHPVGAVRSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKH5</accession>
    <name>C7QKH5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796799.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8251"/>
    <dbReference type="EnsemblBacteria" id="ACU77074">
        <property type="protein sequence ID" value="ACU77074"/>
        <property type="gene ID" value="Caci_8251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8251"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_2_1_11"/>
    <dbReference type="OMA" id="KVTVRYW"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="8497" checksum="947014CA256A1984" modified="2009-10-13" version="1">MSGLIRYWAAAKAAAGIAEEPFEGEVLADVLAAAVARHGAGLGEVVRRASFLVDGTQVGRRDPADVRLPEGAVVEVLPPFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT9</accession>
    <name>C7PVT9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2413"/>
    <dbReference type="EnsemblBacteria" id="ACU71331">
        <property type="protein sequence ID" value="ACU71331"/>
        <property type="gene ID" value="Caci_2413"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2413"/>
    <dbReference type="eggNOG" id="COG0759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1591590_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="17761" checksum="CEBF14DAE50DE229" modified="2009-10-13" version="1">MGAAMDDEIGTGEILDEDTARRDRRRWSSDRCLDDTCDLECLSSGTCCESAGFLDGNCLLGLTTLTGTIGGLLAALAGTGPVGRRLRTEPRVPPGPLAAALHRGVRYYQVRISARRPGYGGCRYAPTCSAYAAEALRRHGALKGTRLAARRLRRCRPGTAGGLDPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD7</accession>
    <name>C7PWD7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793114.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4522"/>
    <dbReference type="EnsemblBacteria" id="ACU73385">
        <property type="protein sequence ID" value="ACU73385"/>
        <property type="gene ID" value="Caci_4522"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4522"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="VNPRMTA"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="2"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="377" mass="39936" checksum="F76475714CEB7F43" modified="2009-10-13" version="1">MIQARGITRTYQTHGAFTGARTVPALRGVDFTLPDGGAVSFIGESGCGKTTLGKILTGLETFDGGELIVDGVALSGLKPRQREKYFRRIQMIHQDPYSALNPTRTVEATLRDPLRMRAKERGASGGGGGDGEGEGGWRARAAELLTLVGLEPAAVLPKYPHQLSGGQRQRVVIARALTVDPEVLIADEAVSMIDVSMRLGILKLLRDLRSRLGISLVFITHDVATARYVGEGGELHVIYRGEVVERGLTDEVILAPVHPYTQCLLSAVPIMRGLEEPGPDRTAPTTALDERTPTPGCLFEPRCPFAQDQCAEKHPVLVPFGLDAVGESGAVGESNAAAAGPATDTGSENGSESGHVHACFYPESRRVVGVEVGAGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWV9</accession>
    <name>C7PWV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77216">
        <property type="protein sequence ID" value="ACU77216"/>
        <property type="gene ID" value="Caci_8393"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8393"/>
    <dbReference type="HOGENOM" id="CLU_1265050_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23899" checksum="D26F2109D7D6A561" modified="2009-10-13" version="1">MSADDIRQTAKVGFRKDLNWVSLPNSFPFGKWGDSREWVENMAAMVYYVGRSQFDGSRPTPEWFIRTCGVIDASWRGFASVKNRYKCLLFHDVDALPAHVAVDAYLGDLPWAEARDIYVGAHHDEVVEGLRVEAFEMAGAEAAVRAVYFTVGDLETRSLVASYNYAFRADGMDVLVRSTFPDLGLVRDALPVLDEFVRGITLSFGGDAGAGAGADAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW4</accession>
    <name>C7PWW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796946.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8398"/>
    <dbReference type="EnsemblBacteria" id="ACU77221">
        <property type="protein sequence ID" value="ACU77221"/>
        <property type="gene ID" value="Caci_8398"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8398"/>
    <dbReference type="eggNOG" id="ENOG5034B47">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097181_0_0_11"/>
    <dbReference type="OMA" id="LTVTYWQ"/>
    <dbReference type="OrthoDB" id="1775967at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025326">
        <property type="entry name" value="DUF4232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14016">
        <property type="entry name" value="DUF4232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982556" evidence="2">
        <location>
            <begin position="39"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="25650" checksum="C0927569A436D0BB" modified="2009-10-13" version="1" precursor="true">MTKRITHIAKPLLPATLTLSALMSMAACGSDSPKPSAAASTPSVSQSQPGTAAPTQTSAPNVADTSTGTQQPAPRTGSGTGTGSATATASKPTTPKPPTAKTSTAPDSTLPGDCSVTHLKGTVTNLARPINHVLLTVTNAGSTTCSLYYYPDLRLDADQQAVTQAVEDSKPQAVVTIAPGESAYAAIGTSSADGSGGTPQLEKQVEVFLESRDQSGSLPGTMTLPLPAGTYVDVDKAFVTYWQSDLQSAIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY4</accession>
    <name>C7PWY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796966.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77241">
        <property type="protein sequence ID" value="ACU77241"/>
        <property type="gene ID" value="Caci_8418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8418"/>
    <dbReference type="HOGENOM" id="CLU_715140_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="41699" checksum="C761671B9D3F9310" modified="2009-10-13" version="1">MRHARQLQAQRRGGDIAGPAWPSIVATTTSLTGAAAGIATTLVWSDPLHLRLGVGMAAAGAVFSSVAMFAARRDRSTRRELVATLREDHAAELRYETTRRDKQISDLKTDALAAEETVVLFEERAKEEQLRADASEAARVRAEHDLAVLSAWVQQTTAAAELTRSAVQSFAQVQPFEPAQQFEPVSVHDHAFASYQAARTGAYELEYDPAYAAQPVYDAVPAYETEYAAYTDYVDYAEFTDQGYGATTYATTPAGAEIDLRPAAAVPVRAPEPQLSAALPAAEPRPLRSAVLAVRDEVGFDVAGEVAGPGRDPYTVPGVVMPRQRADGLPPSLPQARPVPPERLYRPYLATDQGTASTSNAAPVDLTMYDETQQMARIEHRETGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX73</accession>
    <name>C7PX73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0472"/>
    <dbReference type="EnsemblBacteria" id="ACU69424">
        <property type="protein sequence ID" value="ACU69424"/>
        <property type="gene ID" value="Caci_0472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0472"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_2_11"/>
    <dbReference type="OMA" id="RINRECH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981331" evidence="1">
        <location>
            <begin position="30"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="113"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="525" mass="56129" checksum="44B61C86FFA47EA6" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXD3</accession>
    <name>C7PXD3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784779.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0546"/>
    <dbReference type="EnsemblBacteria" id="ACU69484">
        <property type="protein sequence ID" value="ACU69484"/>
        <property type="gene ID" value="Caci_0546"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0546"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_11"/>
    <dbReference type="OMA" id="IIYGQSE"/>
    <dbReference type="OrthoDB" id="839689at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="17"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="41615" checksum="4CC34018ACD3A39F" modified="2009-10-13" version="1">MTLRTSPPHPGLAGGPVYLDYNATTPVDPRVADAMVPHLTYLFGNPSSSHAYGAGPRTAMQRARGQVAAVIGARSEGEIVFTGSGSEADLLALRGAVLAAGGPRPHVITQVTEHPAVLETCSALERLHGAQVTVLPVDGYGMLEPSTLAAALERPTALVSVMAANNETGALQPIAELAALAHARGALFHCDAAQAVGKIALDVRALGVDLLTIVGHKMYAPKGVAALYVREGVRLEPVVYGGGQERALRSGTESVALAVALGAAAELVVEDLAHNEPARVAALRDELHRLLTAGWPGRVRLNGPDAARLPNTLNVSIDGVRGYEMLASVPDVAASTGSACHSGDHTTPSAVLTAMGFDEDRALGSVRLSLGRWSTRREVEKAARALIGHKLPNRDEAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL2</accession>
    <name>C7PXL2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2547"/>
    <dbReference type="EnsemblBacteria" id="ACU71465">
        <property type="protein sequence ID" value="ACU71465"/>
        <property type="gene ID" value="Caci_2547"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2547"/>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_1_0_11"/>
    <dbReference type="OMA" id="IRIHYVR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33137" checksum="F1647D8EE1DDF0E2" modified="2009-10-13" version="1">MAETIRRAVIPAAGIGSRMLPLTKAIPKEMLPVGDRPVIEHTVRELVASGITDITIVVSGGKSLIQDHFRPNPALVEQLRAAGKDDYAQAVEDVAELARAGHITYQDQHGPYGNGTPVLNAARGLGSTEPMLVLWPDDVFVAEVPRAQQLIAAYEATGCPMLALMPMDRSQSQRYGVPIVHEDLGEGLLRISGLLEKPKPADAPSDFAAIGGYVVTPGIVEELHEATVRWSRQRTGEVYLTDAINAYAETRAVYGQVIAGHWYDTGNPADYLVAQFAHALADPEYGPVLRSLAAGIDAGLDSGNGGGGGASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT3</accession>
    <name>C7PXT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793122.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4530"/>
    <dbReference type="EnsemblBacteria" id="ACU73393">
        <property type="protein sequence ID" value="ACU73393"/>
        <property type="gene ID" value="Caci_4530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4530"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="NMATWML"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="126"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="233"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="389" mass="41822" checksum="EFB0F7AB7DB96D6D" modified="2009-10-13" version="1">MAADFDLFKVSEEHDLLREAVRSLCEEKILPFAADVDEHSRFPQEALDALVSSDLAAVHVAEQYGGQGADALATCIVIEEVARVCASSSLIPAVNKLGSMPVILSGSEELKQKYLTPLAAGSGMFSYCLSEPDAGSDAAGMKTRADRDGDDYVLNGVKRWITNAGVSEYYTVMAVTDPTARSKGISAFVVEKGDEGVTFGAPEKKLGIKGSPTREVYFDNVRIPADRMIGAEGTGFATAMRTLDHTRVTIAAQALGIAQGALDYASNYVKERKQFGKPIADFQGIQFMLADMAMKLTAARQLTYTAAAKSERGDSDLTYFGAAAKCFASDVAMEVTTDAVQLLGGYGYTKDYPLERMMRDAKITQIYEGTNQVQRVVMARQVLAGGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY00</accession>
    <name>C7PY00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793189.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4598"/>
    <dbReference type="EnsemblBacteria" id="ACU73460">
        <property type="protein sequence ID" value="ACU73460"/>
        <property type="gene ID" value="Caci_4598"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4598"/>
    <dbReference type="HOGENOM" id="CLU_2680934_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="7424" checksum="5A7E872C1434AE7E" modified="2009-10-13" version="1" precursor="true">MDTKWGITTLVVGAYLLALGIAGINANSGGVVAVFAVVLVLGFVLTGWSVVLPWDGGKARAAAHRDAPGPVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYZ3</accession>
    <name>C7PYZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784844.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0613"/>
    <dbReference type="EnsemblBacteria" id="ACU69549">
        <property type="protein sequence ID" value="ACU69549"/>
        <property type="gene ID" value="Caci_0613"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0613"/>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134850_0_0_11"/>
    <dbReference type="OMA" id="LVIESWH"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="2">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15510" checksum="1E2B5A1F59812394" modified="2009-10-13" version="1">MATWQQFAESAPDLAAPVRARLTATKHHVLATLRKDGTPRVSGTEVDFTPEGHLHLGSMADAQKGKDLKRDPRFALHANPGDGSMDGGDAKLSGRATPLPTEGPDDAFDLDLHEVVLTTVENDQLVIRLWTPENGLREIRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ04</accession>
    <name>C7PZ04_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0624"/>
    <dbReference type="EnsemblBacteria" id="ACU69560">
        <property type="protein sequence ID" value="ACU69560"/>
        <property type="gene ID" value="Caci_0624"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0624"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_11"/>
    <dbReference type="OMA" id="DWRAVEN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="1">
        <location>
            <begin position="118"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="36248" checksum="1E2A86B03BC56B7B" modified="2009-10-13" version="1">MDRPHAVLAMRPALRPLLFDADAEERLARLAEADPEAVVTDFADPRAAGALVRAEVLITGWDCPVLDEPALARMPALRAVLHSGGSVKHHMTDAAWARGLLVSSAVADNAVPVAEYTLAMVISAGKRLPEMERAFRAGRDGRDWLHWSEGFVPVGNHRRVIGVVGLSRVGRRVVEMLRVLDATVLVHDPYVPDEVVRGLGAVPTGLDALVAASDVVSLHAPSTAETRHQMDRRRLALMKDGATLINTARGALVDTAALADELRAGRLYAVADVTDPDPLPPDSELFDLPNLTLTPHVAGSIGGELRRLGDFVLAELRRLTAGTELLGRVLPETLPSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ91</accession>
    <name>C7PZ91_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2631"/>
    <dbReference type="ESTHER" id="catad-c7pz91">
        <property type="family name" value="RsbQ-like"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71548">
        <property type="protein sequence ID" value="ACU71548"/>
        <property type="gene ID" value="Caci_2631"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2631"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_30_0_11"/>
    <dbReference type="OMA" id="VCPSPCF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28782" checksum="9200C0014F5B8FCA" modified="2009-10-13" version="1">MWGMDVRSRHHVTVEGPVGAPVMVLAHGFGCDQNMWRLVVPRLAEQFQVVLFDHVGAGRSDSSAWSEERYRTLDGYADDVIEILRDLDAGPVVFVGHSVSASVGVLAAVREPELFAKLILLNPSPCFVDDGDYRGGFSAEDIEELLESLESNYLGWSAAMAPVIMGNPERPELGEELTNSFCRMDPAIARVFARATFLSDNRSDLAGVTVPTLVVQCSQDVIAPPEVGAFVQAQIAGSVLETLPATGHCPQLSAPQATAEAIVEFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS9</accession>
    <name>C7PZS9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase D subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4733"/>
    <dbReference type="EnsemblBacteria" id="ACU73594">
        <property type="protein sequence ID" value="ACU73594"/>
        <property type="gene ID" value="Caci_4733"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4733"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_2_3_11"/>
    <dbReference type="OMA" id="THYYQTV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017609">
        <property type="entry name" value="Xanthine_dehydrogenase_dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03196">
        <property type="entry name" value="pucD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="2">
        <location>
            <begin position="36"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="779" mass="83003" checksum="0C3798C317DD3FD9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT4</accession>
    <name>C7PZT4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793328.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4738"/>
    <dbReference type="EnsemblBacteria" id="ACU73599">
        <property type="protein sequence ID" value="ACU73599"/>
        <property type="gene ID" value="Caci_4738"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4738"/>
    <dbReference type="eggNOG" id="COG2351">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115536_1_0_11"/>
    <dbReference type="OMA" id="ENQNYHI"/>
    <dbReference type="OrthoDB" id="1955791at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000895">
        <property type="entry name" value="Transthyretin/HIU_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="PTHR10395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00189">
        <property type="entry name" value="TRNSTHYRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="SSF49472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TR_THY" evidence="8">
        <location>
            <begin position="3"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600895-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11859" checksum="D111B4CF2A5C4567" modified="2009-10-13" version="1">MSLSTHVLDAVLGRPAAAVPVRLDVARPDGWLPVARERTDADGRIRFAAELLGGPHRLVFDTAAYFRAAGVADFFYPEVAIAFTITDPDAHHHVPLLLSPFAYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q045</accession>
    <name>C7Q045_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795267.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6692"/>
    <dbReference type="EnsemblBacteria" id="ACU75538">
        <property type="protein sequence ID" value="ACU75538"/>
        <property type="gene ID" value="Caci_6692"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6692"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="AQFIVHD"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="213"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33767" checksum="FD2E15F21CEC2CFE" modified="2009-10-13" version="1">MHTVAIIALDGVIPFDLATPIEVFTRSRLPDGRSGYQVRVCAEHPELDAGAFTLRAPWGLEALQDADTIIVPGVAEPLAPLPTTVREALRAAAANGTRIASICTGTFPLAATGLLDGLRATTHWIAAERLAAAYPAIDVDASVLYVDNGQILTSAGAAAGLDLCLHLIRKDYGSAVAAHAARLSVMPLEREGGQAQFIVHDHTPVAPRGATLEPLLAWLRDNLNRDLTLPDIAAEAGLSTRTLIRRFREQTGTTPLQWLHRARVRRAQHLLETTQHPVERIATQVGFGSATAFRDRFKKTTGTSPNAYRRTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0U6</accession>
    <name>C7Q0U6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Adenosine deaminase</fullName>
            <ecNumber evidence="1 3">3.5.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2 3">Adenosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">add</name>
        <name evidence="5" type="ordered locus">Caci_0789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2'-deoxyadenosine + H(+) + H2O = 2'-deoxyinosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:28190"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17256"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:28997"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="1 3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0789"/>
    <dbReference type="EnsemblBacteria" id="ACU69724">
        <property type="protein sequence ID" value="ACU69724"/>
        <property type="gene ID" value="Caci_0789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0789"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039228_0_0_11"/>
    <dbReference type="OMA" id="NHFTIHA"/>
    <dbReference type="OrthoDB" id="554648at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046936">
        <property type="term" value="F:2'-deoxyadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00540">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028893">
        <property type="entry name" value="A_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A_deaminase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="3">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="40712" checksum="FBD115DE682BBFFA" modified="2009-10-13" version="1">MDEELIRRAPKALLHDHLDGGLRPQTVIELADEYGYANLPQYDGTADGLGRWFAEAADSGSLPRYLETFEHTVGVMQHADALFRVAAECAEDLAADGVVYAESRYAPEQHLEAGLSLDEVVEAVDAGFREGERRAAAAGNRIQVGTLLTAMRHAARSSEIAELAVRHRDRGVSGFDIAGAEAGYPPTRHLDAFEYLRRENFHFTIHAGEAFGLPSIWEALQWCGADRLGHGNTIMDDILVDADGKATLGRLAAYVRDKRIPLEMCPTSNLQTGAARSYESHPIGLLRELHFRVTVNTDNRLMSSTSMTREFTELHKAHGYTLEDMQWFTINALKSAFLAFDQRLELINEHVKPAYERLRAEASPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q145</accession>
    <name>C7Q145_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2810"/>
    <dbReference type="EnsemblBacteria" id="ACU71720">
        <property type="protein sequence ID" value="ACU71720"/>
        <property type="gene ID" value="Caci_2810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2810"/>
    <dbReference type="HOGENOM" id="CLU_2599572_0_0_11"/>
    <dbReference type="OrthoDB" id="1959063at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8258" checksum="B162CE08883EE4E1" modified="2009-10-13" version="1">MDNVLVLLLTDSTFVNAQGGTGQTTGVFPVQMRWIAEDWKIGAIGRTGQHYSGLAATPDTQDAVKLGWLALIAATGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q162</accession>
    <name>C7Q162_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787030.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2828"/>
    <dbReference type="EnsemblBacteria" id="ACU71737">
        <property type="protein sequence ID" value="ACU71737"/>
        <property type="gene ID" value="Caci_2828"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2828"/>
    <dbReference type="HOGENOM" id="CLU_1624158_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17653" checksum="2A2AC23F939AADEB" modified="2009-10-13" version="1" precursor="true">MATHSALSSLWPVVVGVGGPSGLAAAGTYFLTRRQHKEQRQQHANDAHEAEHQHDVQTAQGLTATALSLLEPVKEALSEAEQRIKALQKQVGDLESAAASLTSAMETLTTSSAAERQQLEEQLAEVTAERDETQDELAAITIERDTLRAELETHRRQSHGGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1H7</accession>
    <name>C7Q1H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4845"/>
    <dbReference type="EnsemblBacteria" id="ACU73706">
        <property type="protein sequence ID" value="ACU73706"/>
        <property type="gene ID" value="Caci_4845"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4845"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_8_5_11"/>
    <dbReference type="OMA" id="MRFFGDM"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014322">
        <property type="entry name" value="RNA_pol_sigma-B/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02980">
        <property type="entry name" value="SigBFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="5">
        <location>
            <begin position="123"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="29280" checksum="FB85A43121138ECE" modified="2009-10-13" version="1">MAPIPVAPEELARERAAARAALARLRKMSPDDSEYEALREYVIGEYMSYARFVAARFRLRGETQADLEQVAYLGLVKAVDNFDPDYGATFLTYATPMIAGEVRRHFRDTTWHVHVPRRAQENALAVRAVERELTQQLGRAPSAAEIGRRLDLSADEVAEAYEASAAHHTASLDVPVAMADGDGASLGDLLGDEDPGFDSVVDREALKPLLAELSPRDKRILLMKFFRNMSQAQIGAEIGVSQMQVSRLLSQIIGSLRDRLEVGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q279</accession>
    <name>C7Q279_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8803</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8803"/>
    <dbReference type="EnsemblBacteria" id="ACU77616">
        <property type="protein sequence ID" value="ACU77616"/>
        <property type="gene ID" value="Caci_8803"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8803"/>
    <dbReference type="HOGENOM" id="CLU_478749_0_0_11"/>
    <dbReference type="OMA" id="IAQTERD"/>
    <dbReference type="OrthoDB" id="923728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="569" mass="62734" checksum="87710BFAD4E56781" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J8</accession>
    <name>C7Q2J8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="9" type="ordered locus">Caci_0908</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0908"/>
    <dbReference type="EnsemblBacteria" id="ACU69840">
        <property type="protein sequence ID" value="ACU69840"/>
        <property type="gene ID" value="Caci_0908"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0908"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113663_3_0_11"/>
    <dbReference type="OMA" id="WPTRNQL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="10157" checksum="70D55BA98EDB86AA" modified="2009-10-13" version="1">MTETSSTSAMSKPDRGRGGDRRPERRRSPLGRMSLFYRQIIAELRKVVWPTRNELTTYTTVVIVFVAIMVGIVATLDYGFSKLVEWVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2L8</accession>
    <name>C7Q2L8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785155.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0928"/>
    <dbReference type="EnsemblBacteria" id="ACU69860">
        <property type="protein sequence ID" value="ACU69860"/>
        <property type="gene ID" value="Caci_0928"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0928"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_0_11"/>
    <dbReference type="OMA" id="RIVQIKL"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="20"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="45059" checksum="902FF0B71A39F924" modified="2009-10-13" version="1" precursor="true">MNTTSSTRGSGSGNGNVRSILISGAGIAGPSLAYWLHRHGFAATVVERSAFLRDSGGAVDFRGEQVKLLKAMGIFDAVKAAETGMGDQVVIDRAGEPVMAFSSAFFSGEVEVERGDLARILFEATREYTDYVFGDWIVGLDQRADGVDVTFASGAAATYDLVVGADGLHSGVRRLAFGPEEQYRTDLGWLIAGFTAPNDLGLDHEGRIYNVPGCGVMAASARDRSRLGVGFVFHAPGLLYDRHDVAAQKDLVAATYADAGWETPSLLQGMREADDLYFDTLSQIHMDRWSTGRVVLLGDAAWCAGPGGSGTGMAMMGAHVLAGELAAATNDHPTAFAAYERTLRPAAKIGQKQGKGSGAFLAPINDKKIATRNKAYKMLTRKLVAGFFNWLTARAANAVEYKEYPTTAATAPALPTTRDSRIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P9</accession>
    <name>C7Q2P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787084.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2882"/>
    <dbReference type="EnsemblBacteria" id="ACU71791">
        <property type="protein sequence ID" value="ACU71791"/>
        <property type="gene ID" value="Caci_2882"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2882"/>
    <dbReference type="HOGENOM" id="CLU_2011149_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="12844" checksum="D7F572AC57A72B93" modified="2009-10-13" version="1">MNAFSPGDKVLFARVSAVGTVVEPTGVGVEHGYYIETAAGTTHFADADQLTLLPTGTPLFNRGDSVQVAPDAPYHAGLTGTVSSPELHGPIFGYWLNLGVNDNYMWTPAEALSALVPGGGEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q347</accession>
    <name>C7Q347_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793512.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4923"/>
    <dbReference type="EnsemblBacteria" id="ACU73783">
        <property type="protein sequence ID" value="ACU73783"/>
        <property type="gene ID" value="Caci_4923"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4923"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_11"/>
    <dbReference type="OMA" id="YHLMGEN"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="270"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="526" mass="55498" checksum="9EEBC9F83722CC8B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q377</accession>
    <name>C7Q377_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4953</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793542.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4953"/>
    <dbReference type="EnsemblBacteria" id="ACU73813">
        <property type="protein sequence ID" value="ACU73813"/>
        <property type="gene ID" value="Caci_4953"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4953"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="LAMTEFR"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="101"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="34782" checksum="9CAC920B763A67E9" modified="2009-10-13" version="1">MPTEGHPALAALRTWEAAPLAEEEPARRTSRRRTRNPLPALVLALFAVFFVLPVLWLVLAATKTDDQLVHGNPLSFGSWHALRANWDALTSYQDDAIFQWLRNSALYSFLALVITLAVAVPAGYALAMTEFRGRRVLLVGTLVVMLMPNATLVVPLFLEVNAAHLIGSMWSIILPYAFYPFGVYLAYIYFSTALPRELLESARLDGCSEFGVFRRVALPLATPIVALVGFFSFVANWTNYFLPYVMLPQSSQLPVQVGLGTLLDDVPQFNPTVGDLAVQRPELALATLLAITPVLIVFLFSQRFLVTGMLAGATKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q400</accession>
    <name>C7Q400_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797482.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8945"/>
    <dbReference type="EnsemblBacteria" id="ACU77758">
        <property type="protein sequence ID" value="ACU77758"/>
        <property type="gene ID" value="Caci_8945"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8945"/>
    <dbReference type="HOGENOM" id="CLU_2341623_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="11164" checksum="6BAD270225A00256" modified="2009-10-13" version="1">MQNEKQVTDTRVTREPDDALKEFRLSAEEMQAAIADGTAVTISVVVEAVFYEDEWWIENRRTKEWVMAETGLAATLDRRSIQMREADAQVVAHSKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q429</accession>
    <name>C7Q429_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0957"/>
    <dbReference type="EnsemblBacteria" id="ACU69889">
        <property type="protein sequence ID" value="ACU69889"/>
        <property type="gene ID" value="Caci_0957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0957"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="QVRIEHT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="176"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="40186" checksum="321E53A0C8D79825" modified="2009-10-13" version="1">MIYHVQSTDTRLIETLRLRRPRRDDVLVAAIVLLLNSGTYLIPGIVPWGPWRYLLETATIVPLLWRESVPVPSALATGALTLIVTATVHPAQPFPYAVLVTQYTIGSVLRGRTRGVLVGLFMAGNVVAEALHQQWGNPEDFLVTFTLSLTALFLGVLMQSEHDSLSVRADRALQAERVRIARDMHDVVGHAVALMVVQAEAGPLLVRDKPERAEAAFEAISAAGRDAMAQLRGLLGTLHQDEGGGRDPLPTLADLDDLVHQVRKAGLQVRIEHTGSASPLSPGAETAAYRVVQEALTNTLKHAQASRAEVRLSWAPSALEITVADNGRGAGDGSADGGGGHGLTGLRERLAPVGGALSWTSPPDTGGFALTAVIPSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4V4</accession>
    <name>C7Q4V4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5042"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM6">
        <property type="family name" value="Carbohydrate-Binding Module Family 6"/>
    </dbReference>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73902">
        <property type="protein sequence ID" value="ACU73902"/>
        <property type="gene ID" value="Caci_5042"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5042"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_259823_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981422" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="5">
        <location>
            <begin position="70"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="5">
        <location>
            <begin position="231"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="375"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1321" mass="133642" checksum="3B604473094E67C6" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4W1</accession>
    <name>C7Q4W1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CHAP domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5049"/>
    <dbReference type="EnsemblBacteria" id="ACU73909">
        <property type="protein sequence ID" value="ACU73909"/>
        <property type="gene ID" value="Caci_5049"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5049"/>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_484586_0_0_11"/>
    <dbReference type="OrthoDB" id="1380439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007921">
        <property type="entry name" value="CHAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05257">
        <property type="entry name" value="CHAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50911">
        <property type="entry name" value="CHAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981423" evidence="2">
        <location>
            <begin position="33"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C51" evidence="3">
        <location>
            <begin position="66"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="562" mass="56383" checksum="119E8106DFD369FA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q582</accession>
    <name>C7Q582_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795579.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7021"/>
    <dbReference type="EnsemblBacteria" id="ACU75851">
        <property type="protein sequence ID" value="ACU75851"/>
        <property type="gene ID" value="Caci_7021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7021"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_6_11"/>
    <dbReference type="OMA" id="YWWISEE"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="6">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="42910" checksum="9D25FBC1159ED26F" modified="2009-10-13" version="1">MNSAVAQGPVALLDAVAPAPHTGAPSVAEARTAVGLGDQEELGPLRIPGPAAPEIAELEAALEEEAETEPEKEAEADQKVNAWADSAGPAGDLFRQYLREIGRVPLLNAVLEVELAQAVEAGLFAEEKLTFQTHLKPQLRRELAILVLEGQAAKRRLIEANLRLVVSIAKRYLGRGMSILDLVQEGNLGLIRAVEKFDYTRGYKFSTYATWWIRQAMSRALADQARTIRVPVHVVELMNRVVRLQRRLLQENGVEPTPDDIAEVLGVAVERVVEVLRLAQEPVSLHAPVGEEDDVALGDLIEDADAVSPADSVAVVMLREHLDALLSTLGEREKRVVQLRYGLTDGQPHTLEEIGRTFGVTRERIRQIEAKTLAKLRGHTYADQLLDYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5F4</accession>
    <name>C7Q5F4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7093"/>
    <dbReference type="EnsemblBacteria" id="ACU75923">
        <property type="protein sequence ID" value="ACU75923"/>
        <property type="gene ID" value="Caci_7093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7093"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_2_11"/>
    <dbReference type="OMA" id="WLDKPYD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="46598" checksum="F75BCF6892AB47AA" modified="2009-10-13" version="1">MNDISRARDEFLDAADRFPEAFRRRLAGGASRRGFLAAGVGLGAAGVLGACATKTKAASSGSGSGSGAASGSSSAAPSEGKLGADKSDSEKVVNFSNWVSYIDVDPDDKNKRPTLDTFKSETGITVNYTEDVNSNDDFFAKIHQQLAAGQDTGRDLMVLSDWMIGKLRQMGYLEPLNLANIPNFKDLLPEAANPAYDPNRKHTVPWALGFTLMGVNLKSAGLTADQAQKLSIKDMMTDAKYKGKVGYFAEMEDGVGFGLLATGADPAKFTDDQFGAAVAYVQKARDNNQIRQFTGNDYINDLTSGNYAMCMAYSGDIAQIDDPNIVWVVPAEGMLWFADNMCIPAMAAHKTNAEKFMNYMLEPKVGAALDDYISYIPSMQGADTAMADVDKDALQNQLIFPDAATKAKAHEFQNLDLKTLDKYVSQFKDVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q604</accession>
    <name>C7Q604_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785395.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1176"/>
    <dbReference type="EnsemblBacteria" id="ACU70101">
        <property type="protein sequence ID" value="ACU70101"/>
        <property type="gene ID" value="Caci_1176"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1176"/>
    <dbReference type="eggNOG" id="ENOG5031XGJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2128267_0_0_11"/>
    <dbReference type="OMA" id="WFRVVRQ"/>
    <dbReference type="OrthoDB" id="1814862at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="114" mass="12559" checksum="0159A8F088BEBDB5" modified="2009-10-13" version="1">MYRQGDVLIVPVTESAVPEGARAAGPKNRRPRESMVLALGESTGHAHALVATRDEGDFYPAPSESEPAYVFLPYGGKVVHEEHGTIPLPEGWFKVVRQREYEPSALRSFRVVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q627</accession>
    <name>C7Q627_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 17">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 17">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Caci_1199</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 17">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="6 17"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1199"/>
    <dbReference type="EnsemblBacteria" id="ACU70124">
        <property type="protein sequence ID" value="ACU70124"/>
        <property type="gene ID" value="Caci_1199"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1199"/>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0460">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_1_0_11"/>
    <dbReference type="OMA" id="LMFYGPG"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016204">
        <property type="entry name" value="HDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000098">
        <property type="entry name" value="Homoser_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11 16 17" id="KW-0521">NADP</keyword>
    <keyword evidence="12 17 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="371"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000098-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU70124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="46602" checksum="74B0C0097B77FC4F" modified="2009-10-13" version="1">MPRSPMRAAPTEAMGFAMRTEPLKVALLGCGVVGSEVARLMTANAADLAARVGVPLELAGIAVRRPNRQREVPGVAPELFTTDAEALVKRDDVDLVIEVIGGIEPSRALILAALESGKSVVSANKALLAEDGATLYQAAEKHGADLYYEAAVAGAIPLLRPLRESLVGDRVSRVLGIVNGTTNFILDRMDTTGAGFTEALEEATSLGYAEADPTADVEGFDAAAKAAILAGLAFHTRVTASDVHREGITEVTAADIASARAMNSVVKLLAICEVDPVAGKVSARVHPAMIPRSHPLAGVREAYNAVFIESESAGQLMFYGPGAGGSPTASAVLGDLVAIARNKMTGRRGPGESAYAGLTVRPVGEARTRYHISLDVDDKPGVLSAVAGIFAEQDVSIATVRQSGRGPDATLVIVTHLAPDAALTATVARLRALDFVRDVSSVMRVESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q692</accession>
    <name>C7Q692_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787391.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72098">
        <property type="protein sequence ID" value="ACU72098"/>
        <property type="gene ID" value="Caci_3190"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3190"/>
    <dbReference type="eggNOG" id="ENOG503361C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775428_0_0_11"/>
    <dbReference type="OrthoDB" id="1997759at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="37724" checksum="5E7006511C340B81" modified="2009-10-13" version="1">MSTENDFSGLRSRLADLTEGPAPASPFDPVRTAAAGRRRVLARRTTAVGGTGTLAVAAVFGIVAAFAPGAPLPARPAAGIGADPLAKRVDFGWLPASLPNVSYISTAGGVGTEAVAEGNKTPDGAPRVDLMLLSDDGLSTLNGNERSIPVHLDDGRKAYWVTQSEGGGLMGDFQLRFPAKDGRWAEMAWSVNWGGVYSFTKISGAPGTVTVSPPGHAAPTSVPASAQWQQDLVHMATEVTDAPAQIPLPLRITGLPDGFKPETGFLWRPSMAGLGAPGTWSVLLIFDYSGPNPTSLEVGLHGTLSEKTAPVAKGTECATSGGLDVCVQGGSGSRGLAEVGGLKGLLKMVTLLGPDEKQWTTDVMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q693</accession>
    <name>C7Q693_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72099">
        <property type="protein sequence ID" value="ACU72099"/>
        <property type="gene ID" value="Caci_3192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3192"/>
    <dbReference type="HOGENOM" id="CLU_2315148_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045635">
        <property type="entry name" value="DUF6412"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19950">
        <property type="entry name" value="DUF6412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005341035" evidence="3">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="9827" checksum="17AD2FD4B7BEFE7C" modified="2009-10-13" version="1" precursor="true">MTHRGATAASLLAAVVTLLAVVGGQNTAVLVASATALALLAATLRRSAFAVLMAGTTVAAQTAAAARSLLRDTAYLPQRDPDAAGRPHPRAPGSNPATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6E7</accession>
    <name>C7Q6E7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3246"/>
    <dbReference type="EnsemblBacteria" id="ACU72153">
        <property type="protein sequence ID" value="ACU72153"/>
        <property type="gene ID" value="Caci_3246"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3246"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="SHDMYEV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="34550" checksum="BD84BAFC89AAFC0D" modified="2009-10-13" version="1">MGIIEVKGLAKSYETRSKRKTTKVDAVVGVDLDVAEGEIFGFLGPNGAGKTSTLRMLATLIPPDAGTAVIAGADLLTQQAKVREAIGYIAQGGATTDDATAREELVLQARMHGISKADAQRRAVAALAAFDLTEYADRQCKTYSGGQRRRVDIAMGIIHDPKVVFLDEPTTGLDPQSRAHMWDEVRRLRTEGMTVFLTTHYLEEADQLCDRVAIIDGGVVVAEGTPDALKREISGDIVTVGVGEDFTEKAAEILKGQAYLSEIEVRDGGRLRLAVDAGETAVPRVMRTLEDAGIATATVEVHRPTLDDVFLTKTGRSLRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6H3</accession>
    <name>C7Q6H3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793737.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5149"/>
    <dbReference type="EnsemblBacteria" id="ACU74008">
        <property type="protein sequence ID" value="ACU74008"/>
        <property type="gene ID" value="Caci_5149"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5149"/>
    <dbReference type="eggNOG" id="ENOG502ZU64">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2092391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12163" checksum="B2E9F68DC2C94A30" modified="2009-10-13" version="1">MMGDHLRADLRAIQDLTGTLHGLAQQLNEAFNYPVGDFTTEAGAADLAAALAEFSDNWTIRQANLLSDLNDLGQVAEAAAATLSATDTHLAQAVNGALTKAETPAPPPHTGRRMPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Q5</accession>
    <name>C7Q6Q5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793819.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5231"/>
    <dbReference type="EnsemblBacteria" id="ACU74090">
        <property type="protein sequence ID" value="ACU74090"/>
        <property type="gene ID" value="Caci_5231"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5231"/>
    <dbReference type="eggNOG" id="ENOG50334X6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067786_2_0_11"/>
    <dbReference type="OrthoDB" id="1794969at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="30753" checksum="CDA26F9A1D720BE1" modified="2009-10-13" version="1">MRTGWVELAAIPAALLVVYLLRTNSWASRHVRVVWNWLKAWARLAPFTTALSLLIAVHAWMLLGLSPRLRNAVLLTHSTTLAHLKQEPLTVLFGSAMWTDVNELLFMALTAFLYLAPLERWIGTWRTVLAFLAGHIGATLLIALWIEETVVLTPEQDRVYSRTIDVGISYGAYACAALLAYRLRWPYRFSVWSLMLAYLLYQASLKDFDAAVDYTPLGHLAAFGIGLALYPLARTERARRRRGDPWIRIPRPTSTFPEGEPTSDNETTSLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T4</accession>
    <name>C7Q6T4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7117</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795675.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7117"/>
    <dbReference type="EnsemblBacteria" id="ACU75947">
        <property type="protein sequence ID" value="ACU75947"/>
        <property type="gene ID" value="Caci_7117"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7117"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="TFALWST"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="226"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="44655" checksum="4EB360018C5F4957" modified="2009-10-13" version="1">MRRTAATSLLLRHADFRRFYIGDVADQFGTSVTSVGVPLVAIATLHAGTFAVSLLSMAAWLPWLVIALPVGVWVDRTRHRPVMLCSAVVSGVLLASVPLVGGGSGGVGIGYLFAVTLLVGAASVFYQTAYRAYLPTLVAPEDLAEGNAKLHGSASAAQIVGRSGGGLFTQALGGLDVMFVNASTFVVSVFCLASIRIREARPVEPAERVMRREIADGLRLVARDPWIRTLTVFGAVSNLALMAYQSILPVFLIRDVGLSAGGVGLLVAAASSGGVCGAFLVRRVAGRVGTARTTLLFEVGLAVPAMLIALTTKGFGTLCYLVGAFCVSAGVVAGNVIKSGFFQAYCPPHLLGRVNASASFVNYGTLPLGALLGGVLGTLVGVPSAMWIATAGVPAAGLVLLLSPMRSVRDLPTAGHQVRPLVSSGGRLRRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7A5</accession>
    <name>C7Q7A5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ordered locus">Caci_1268</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785487.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1268"/>
    <dbReference type="EnsemblBacteria" id="ACU70193">
        <property type="protein sequence ID" value="ACU70193"/>
        <property type="gene ID" value="Caci_1268"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1268"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_4_2_11"/>
    <dbReference type="OMA" id="TQGRNMA"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU70193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="617" mass="64452" checksum="9E168048BECFA4A9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I2</accession>
    <name>C7Q7I2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787468.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3268"/>
    <dbReference type="EnsemblBacteria" id="ACU72175">
        <property type="protein sequence ID" value="ACU72175"/>
        <property type="gene ID" value="Caci_3268"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3268"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069365_2_0_11"/>
    <dbReference type="OMA" id="HPWRRFV"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="35"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24456" checksum="98660D4960CA4D2B" modified="2009-10-13" version="1">MAAVTVLTEAADPYCLRAGEAGALLAGHPWRRFAVLGDSIAEGVADEVPGYSPLPCADRVAAELTRINPDLAYLNLGKRGLRAHEVREGQLEPALAFAPDLAFVACGANDALRPGYEARADAVDSEIAAVIRALQERGVLVVTVSIFVRPVYPSLPTWLRPTGTERMAMLGARTSAIAAALGTVHVDLTAHPIATAMDSTSADGLHGNARAQSVAATETIRALGRMLRRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D3</accession>
    <name>C7Q8D3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7292"/>
    <dbReference type="EnsemblBacteria" id="ACU76121">
        <property type="protein sequence ID" value="ACU76121"/>
        <property type="gene ID" value="Caci_7292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7292"/>
    <dbReference type="eggNOG" id="COG3609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194678_0_0_11"/>
    <dbReference type="OMA" id="NAYANAW"/>
    <dbReference type="OrthoDB" id="2080614at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="8031" checksum="3E31BA0A28D61FCD" modified="2009-10-13" version="1">MATKLSISLPDADVAFLDELDRNSRSAAVQAAIKLARSVRIVDDYTAAYDEWVSSGEAEVWDGVVGDGIADEADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8K2</accession>
    <name>C7Q8K2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="6">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785561.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1344"/>
    <dbReference type="EnsemblBacteria" id="ACU70267">
        <property type="protein sequence ID" value="ACU70267"/>
        <property type="gene ID" value="Caci_1344"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1344"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="30"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="38134" checksum="B19C6B500D6230A8" modified="2009-10-13" version="1">MPTSGSGVNKPGAAAGSGRAAVVGKNKNRLTIADIAREVGVSPSAVSFALNGRPGVSEATRARILQAAERMNWHPHSAARALGGAPAGAVGLVLARPTRTLGAEPFYAQLIYGMQSVLSARSVALLLQVVDDTEAELAVYRRWSGEQRVDGLLIVDPQTKDPRIAAVEGLGVPAVVLGGHGKHGELPTVWADDREAMLETVRYLAALGHSRIAHVAGTPAFQHTQRRIRALKDAAVQLGLADTQSVPTDFSDGEGAAVTRRLLSQPDAPTAIVYDSDLMAVAGLGVATEMGVRVPAELSIVSFDDSVLTRVVHPAITALSRDTHALGVQVAEALLRIVEEPGTVGDIKAATPRLTVRESTAKPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8N0</accession>
    <name>C7Q8N0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein CrgA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">crgA</name>
        <name evidence="5" type="ordered locus">Caci_1372</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CrgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785589.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70295">
        <property type="protein sequence ID" value="ACU70295"/>
        <property type="gene ID" value="Caci_1372"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1372"/>
    <dbReference type="eggNOG" id="ENOG502ZHAG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2407865_0_0_11"/>
    <dbReference type="OMA" id="DSPPWIG"/>
    <dbReference type="OrthoDB" id="2077515at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00631">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009619">
        <property type="entry name" value="CrgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06781">
        <property type="entry name" value="CrgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9753" checksum="CACAEF910A7B6C46" modified="2009-10-13" version="1">MNDKPSPPWFGALILGSLTTATIWILTYTLSPLPGQHALGGWNYAIVGALLSTFIALSMRWHGDPLEKSRREARSARAERSGAGNSTAGSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T0</accession>
    <name>C7Q8T0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1422"/>
    <dbReference type="EnsemblBacteria" id="ACU70345">
        <property type="protein sequence ID" value="ACU70345"/>
        <property type="gene ID" value="Caci_1422"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1422"/>
    <dbReference type="eggNOG" id="COG4991">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_617768_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982911" evidence="1">
        <location>
            <begin position="34"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="443" mass="45982" checksum="1ED074E7D583C15B" modified="2009-10-13" version="1" precursor="true">MTIPLYKRAALGAAAVLAVTTVTTGAITGTAQAATSGARWTENLSHTQSSDFNVAWTGRALTVKDGRVHASTSQDTRGYGLDVLPEHSLATPANEVAVTVTAARPAGSDAQVDVRGLGLNGIWTQWIPAAATGSTSLSESVTTVQARITLRDSAQGAAPTISNLILSADNGAAADAAPNLAPASVSYQVYATREGLVGGTTANGHVIQSNDHFVALPSGTALSPNGSGSYSVQVCGPSRCETAPVWDVGPWNTRDNYWDASRAEFTNLPQGEPEAQAAYQSGYNGGLDQFGRHVSNPAGIDLADGTFYNVGLNNNGWVTVTYLWTGGGGSGPSVTGMGQCATSSAADCWNTAAGNGSDCHSGHFCIYTGTNYSGKVFSFYHCKYNGGDWALQNWLSAGSYINDNSGGTDAYTKDQNHNVITATAPGSRSTNYNFNPVYFVQAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q915</accession>
    <name>C7Q915_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3429"/>
    <dbReference type="EnsemblBacteria" id="ACU72335">
        <property type="protein sequence ID" value="ACU72335"/>
        <property type="gene ID" value="Caci_3429"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3429"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011068_1_0_11"/>
    <dbReference type="OMA" id="LTAARWM"/>
    <dbReference type="OrthoDB" id="1406236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lant_dehydr_N" evidence="1">
        <location>
            <begin position="81"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="782" mass="84858" checksum="C278764D0A66DF21" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q938</accession>
    <name>C7Q938_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3452"/>
    <dbReference type="EnsemblBacteria" id="ACU72358">
        <property type="protein sequence ID" value="ACU72358"/>
        <property type="gene ID" value="Caci_3452"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3452"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1218033_0_0_11"/>
    <dbReference type="OMA" id="THGQIAT"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="23856" checksum="9B515F5B6D108702" modified="2009-10-13" version="1">MYFQRTHWENEVIRADLLSSSPIYLVGLIQILKDAGITVVSVRTVVDSEPFWVADVIVVDAETLPGDDPRPVAAMAACAPVLIVNHDHVVEPEAYLRAGAAGVVERREPGECIANAVRAVAAGIAIAPCTCTAAEQLSAPADAEADPEAGAGGLSGREAQVLRHISLGLTHGQIATRLGISPHTVDTYVKRIRSKLGAGNKAELTRAALLGRDHKAARPALRGGRTA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2016-03-16" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q942</accession>
    <name>ORR3O_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-ornithine/L-arginine 3-hydroxylase</fullName>
            <ecNumber evidence="3">1.14.11.-</ecNumber>
            <ecNumber evidence="3">1.14.11.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-ketoglutarate-dependent dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-ornithine/L-arginine hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">ODO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3456</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2014" name="ChemCatChem" volume="6" first="3012" last="3017">
            <title>Synthesis of mono- and dihydroxylated amino acids with new alpha-ketoglutarate-dependent dioxygenases: biocatalytic oxidation of C-H bonds.</title>
            <authorList>
                <person name="Baud D."/>
                <person name="Saaidi P.-L."/>
                <person name="Monfleur A."/>
                <person name="Harari M."/>
                <person name="Cuccaro J."/>
                <person name="Fossey A."/>
                <person name="Besnard M."/>
                <person name="Debard A."/>
                <person name="Mariage A."/>
                <person name="Pellouin V."/>
                <person name="Petit J.-L."/>
                <person name="Salanoubat M."/>
                <person name="Weissenbach J."/>
                <person name="de Berardinis V."/>
                <person name="Zaparucha A."/>
            </authorList>
            <dbReference type="DOI" id="10.1002/cctc.201402498"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>SUBSTRATE SPECIFICITY</scope>
        <scope>BIOTECHNOLOGY</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-ornithine and L-arginine, leading to (3S)-3-hydroxy-L-ornithine and (3S)-3-hydroxy-L-arginine, respectively. Cannot use L-lysine, D-ornithine, or D-arginine as substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-ornithine + O2 = (3S)-3-hydroxy-L-ornithine + CO2 + succinate</text>
            <dbReference type="Rhea" id="RHEA:40931"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:77411"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-arginine + O2 = (2S,3S)-hydroxyarginine + CO2 + succinate</text>
            <dbReference type="Rhea" id="RHEA:36607"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:73938"/>
            <dbReference type="EC" id="1.14.11.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="1">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="biotechnology">
        <text evidence="6">Being totally regio- and stereoselective, this enzyme is of interest for biocatalytic purposes to produce chiral scaffolds that are of synthetic value in the preparation of more complex functionalized chiral molecules such as natural products and analogs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the clavaminate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="3"/>
    <dbReference type="EC" id="1.14.11.41" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787655.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7Q942"/>
    <dbReference type="SMR" id="C7Q942"/>
    <dbReference type="STRING" id="479433.Caci_3456"/>
    <dbReference type="EnsemblBacteria" id="ACU72362">
        <property type="protein sequence ID" value="ACU72362"/>
        <property type="gene ID" value="Caci_3456"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3456"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044078_0_0_11"/>
    <dbReference type="OMA" id="FIDNFRA"/>
    <dbReference type="OrthoDB" id="1742732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102525">
        <property type="term" value="F:2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023966">
        <property type="entry name" value="Arginine_beta-hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014503">
        <property type="entry name" value="Clavaminate_syn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019543">
        <property type="entry name" value="Clavaminate_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03946">
        <property type="entry name" value="viomycin_VioC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0223">Dioxygenase</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000435697" description="L-ornithine/L-arginine 3-hydroxylase">
        <location>
            <begin position="1"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q9Z4Z5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source ref="2"/>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source ref="2"/>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000305" key="6">
        <source ref="2"/>
    </evidence>
    <evidence type="ECO:0000312" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="39116" checksum="A8CBD5ED9EEE22AF" modified="2009-10-13" version="1">MHRLALTAQDNLAVAPMLADLAGRYPDIEDPELIRSAPVLAAKGLPPHLLAFLDDFRLREPSALCVISGLDVDQDRLGPTPEHWRDSQIGSRSLNLEIFFLLCGAALGDVFGWATQQDGRIMHDVLPIKGHEHYELGSNSLQHLSWHTEDSFHPCRGDYVALMCLKNPYEAETMVCDAGDLDWPNLDVDALFEPVFTQMPDNSHLPQNTAESTGDPTKDRLRARSFELIKSWNENPVRRAVLYGDRQNPYMALDPYHMKMDDWSERSLEAFQALCEEIEAKMQDVVLHPGDIAFIDNFRAVHGRRSFRARYDGSDRWLKRLNITRNLRGSRAWRPAPDDRVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9A1</accession>
    <name>C7Q9A1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793976.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5388"/>
    <dbReference type="EnsemblBacteria" id="ACU74247">
        <property type="protein sequence ID" value="ACU74247"/>
        <property type="gene ID" value="Caci_5388"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5388"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_7_4_11"/>
    <dbReference type="OMA" id="QAWEPHP"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="77"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="26012" checksum="845013F3B3982419" modified="2009-10-13" version="1">MSSTILDPASAPQAGGRGVLESAFALLGALEQTGAAGVTRLAAECGLPKTTAHRLLEQLSSLGAVERSRGGYRIGARVFQLGHSWQPYRALRAAVREPMRRLAAATGVTVTVNVLRNGEDMIVDWTAGRDGLPVPLRSGGTWPWNTAAGKALAAGRHAGTTDSSPRIPFPASASWRREVATIRERGVAFDREEVVSGVCCAAVPLHGAPGTPIAALCVITDPSHNLDRLAGALQNAGRAAGAALRESPSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I2</accession>
    <name>C7Q9I2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">argB</name>
        <name evidence="9" type="ordered locus">Caci_5469</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794057.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5469"/>
    <dbReference type="EnsemblBacteria" id="ACU74328">
        <property type="protein sequence ID" value="ACU74328"/>
        <property type="gene ID" value="Caci_5469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5469"/>
    <dbReference type="eggNOG" id="COG0548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053680_0_1_11"/>
    <dbReference type="OMA" id="EGLYEDW"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04250">
        <property type="entry name" value="AAK_NAGK-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041727">
        <property type="entry name" value="NAGK-C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="38"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="31650" checksum="2E827E21720B96CE" modified="2009-10-13" version="1">MSTAQSLAAAASARRHDALAKAGILTEALPWLSALHGKTIVVKFGGNAMIDKELEAAFAKDIVFLRYAGLRPVVVHGGGPQINAQLDRLGIEHRFAGGLRVTTDETMDVVRMVLTGQVQRDIVGIINTHGPFAVGMSGEDADTLKAIKRHAVVDGQSVDIGRVGDIEAVNPGAINALLDDGRIPVVSSIARAADGTGVYNVNADTAAAALAVGLGAEKLVVLTDVEGLFADWPASDEVISRLSADELAELLPTLSAGMVPKMEACLRAVRGGVPRAHVLDGRVPHALLLEVFTDEGIGTMVVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I3</accession>
    <name>C7Q9I3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="7">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
                <shortName evidence="7">AGSase</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">argJ</name>
        <name evidence="8" type="ordered locus">Caci_5470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794058.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5470"/>
    <dbReference type="EnsemblBacteria" id="ACU74329">
        <property type="protein sequence ID" value="ACU74329"/>
        <property type="gene ID" value="Caci_5470"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5470"/>
    <dbReference type="eggNOG" id="COG1364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_2_0_11"/>
    <dbReference type="OMA" id="DYVHENS"/>
    <dbReference type="OrthoDB" id="1083409at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023330048" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023330047" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="179"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="178"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="38456" checksum="0F4B506918881241" modified="2009-10-13" version="1">MSVTSAKGFRASGIAAGIKDSGNPDLALVVNDGPLTAAAGVFTSNRVKAAPVVWSEQVLKSGAVKAVVLNSGGANACTGPAGFQDTHKTAEELAALLDASAAEVAVCSTGLIGVRLPMEALLSGLKTAAGALAADGGAAAATAIMTTDTVAKTAEARGTGYAVGGMAKGAGMLAPGLATMLVVLTTDAVADAGVLDSVLRAATKVTFDRVDSDGCMSTNDTVLLLASGASETVPDLAEFQAAVTSVCADLARQLIGDAEGATKDIAVEVVRAASEDEAVQVAKAVTRSNLFKCAMYGNDPNWGRVLSAVGTTDAAFEPDQLSVAINNVWVCRDGGVGEDRDLVDLTGREVKVTVDLAAGTSSATVWTNDLTPGYVHENSAYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9S4</accession>
    <name>C7Q9S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7417"/>
    <dbReference type="EnsemblBacteria" id="ACU76243">
        <property type="protein sequence ID" value="ACU76243"/>
        <property type="gene ID" value="Caci_7417"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7417"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051806_4_1_11"/>
    <dbReference type="OMA" id="ICAWHSI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="30758" checksum="16581E95009A8217" modified="2009-10-13" version="1">MSTTDVRRDADFDHGPVRSGPGRGRWGRMVHSPLGWALAGLVGVGLVAGVTATGPGPVPVLGGGVAVGVYWVVMRRLARRATPEITGRGAARQALLGSAMGLGFVAVSTLLIVAFGGYSFSWAHHAVGGTLASVLAVQAGAALTEELMFRGVALQAIEQRWGTVVAVAVTALFFGAVHMANPGATLWSGMAIAVEAGVMLGAAFLWQRSIWLVVGLHFVWNSVEQLLGVPVSGHPADARLLNVRTSGSHLLTGGAFGLEASVVPVAISLLLAIPMFVAARRRGNVLPARRADRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y3</accession>
    <name>C7Q9Y3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796027.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7477"/>
    <dbReference type="EnsemblBacteria" id="ACU76302">
        <property type="protein sequence ID" value="ACU76302"/>
        <property type="gene ID" value="Caci_7477"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7477"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="RGAMLLC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34884" checksum="9E84BD0FC8D4D9D6" modified="2009-10-13" version="1">MEIREVEAFLAVAEELHFGRAATRLHVTPTSVSQNIRSLERRVGAPLFERTTRRVSLTPLGERLLADLRPAYQAMEAALNTAHEAAAHHTASLRVAFATSMSRRISAEMVDAFRRSRPQCQVVRTALPTAALHAKQVPDLGDIDLFITWAPGGPAVLQAPGWVVGPVLATVPRALLVARNHPLAGRATVDAEELTDHPLFFMQSTEPASDRMAGYIDAWTPSHTPEGRPLNRVRHMNGPYVEELITTIAEGWLAHVTVEGLTEIYQHQNVTAVLLTGLPPIPIVAAWPATGHNPMVKAFVQAAIASQDGTPPLAGGRPGAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD1</accession>
    <name>C7QAD1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD_binding_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792159.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3524"/>
    <dbReference type="EnsemblBacteria" id="ACU72430">
        <property type="protein sequence ID" value="ACU72430"/>
        <property type="gene ID" value="Caci_3524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3524"/>
    <dbReference type="eggNOG" id="COG4529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_431952_0_0_11"/>
    <dbReference type="OMA" id="WESHHHR"/>
    <dbReference type="OrthoDB" id="1239213at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="2">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="633" mass="69308" checksum="76E74504FB727B15" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAJ9</accession>
    <name>C7QAJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792227.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3593"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72498">
        <property type="protein sequence ID" value="ACU72498"/>
        <property type="gene ID" value="Caci_3593"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3593"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023231_2_0_11"/>
    <dbReference type="OMA" id="DIATWHT"/>
    <dbReference type="OrthoDB" id="956236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982679" evidence="1">
        <location>
            <begin position="30"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="723" mass="73390" checksum="32DE82076B70ABF9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAQ8</accession>
    <name>C7QAQ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5522"/>
    <dbReference type="EnsemblBacteria" id="ACU74381">
        <property type="protein sequence ID" value="ACU74381"/>
        <property type="gene ID" value="Caci_5522"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5522"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_10_0_11"/>
    <dbReference type="OMA" id="PMFTPFR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="3">
        <location>
            <begin position="135"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="399"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="791" mass="85770" checksum="1D2912C591E8C9DF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAR5</accession>
    <name>C7QAR5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF402 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5529"/>
    <dbReference type="EnsemblBacteria" id="ACU74388">
        <property type="protein sequence ID" value="ACU74388"/>
        <property type="gene ID" value="Caci_5529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5529"/>
    <dbReference type="eggNOG" id="COG3557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1650850_0_0_11"/>
    <dbReference type="OMA" id="YWRDRWY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007295">
        <property type="entry name" value="DUF402"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035930">
        <property type="entry name" value="FomD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04167">
        <property type="entry name" value="DUF402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159234">
        <property type="entry name" value="SSF159234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF402" evidence="2">
        <location>
            <begin position="64"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20328" checksum="1A1622A79E1ED44C" modified="2009-10-13" version="1">MSNENSLLKLNTSITVRLVKTPRPDVEYPVVVRHDDGEHIVVVGPWASDTGARDMGFTVFEPGDVWTEHYWRSRWYSIKEVRDASGAVKGWYCDVTRPPTVRAGDGGGGSDGGGGSDGEGPSLVIGDLDLDLWLSGDTTQILRLDEDEFAESGLTEREPETAAQAVASLDELEAMARCGAFPMLLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAX6</accession>
    <name>C7QAX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794178.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5590"/>
    <dbReference type="EnsemblBacteria" id="ACU74449">
        <property type="protein sequence ID" value="ACU74449"/>
        <property type="gene ID" value="Caci_5590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5590"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_2_11"/>
    <dbReference type="OMA" id="MQEDYMR"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="97"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="35219" checksum="032C1452AAC839D9" modified="2009-10-13" version="1" precursor="true">MGPFLLRRIVNYLVLITLATCLGYLLAASSLSPREYFSRRQPPPPAASVNATLTQLNLNDKTPLPDRFEHWAGGVLTGDLGKTIDDTSVSAEMGRRIGVTLRLVLVGTISGALVGVALGFVSAIRQYRPSDHAITFLSFLVLSTPVFLLAVLLKIGTVKVNQAAGTTLLPYTNETTPGLAGGWLRHLTDRAQHLVVPTLSLMLGQAALFSRYQRSAMLDVLGADYIRTARATGMRRGPALVKHGLRTALIPMATLFAYQMGLLLTGVTFTEKIFGWHGMGEWFVDSIGREDVNSVAAMVLFTAVLVLIAGLLSDIAHALLDPRVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBV5</accession>
    <name>C7QBV5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">B3/4 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792303.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3672"/>
    <dbReference type="EnsemblBacteria" id="ACU72574">
        <property type="protein sequence ID" value="ACU72574"/>
        <property type="gene ID" value="Caci_3672"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3672"/>
    <dbReference type="eggNOG" id="COG3382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076869_0_0_11"/>
    <dbReference type="OrthoDB" id="1424960at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B3_4" evidence="1">
        <location>
            <begin position="66"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="26661" checksum="B41DAE6D3D65739C" modified="2009-10-13" version="1">MEFLTVSVQDRVLDLVPGYVLGLIAVPAVEVTPTPPEVSELLTAAEDRLHALGLGKAEVSALPPIAAWREAYRQVGANPNKFPCAAESLTRRVAKGDRLPRINSLVDLCNTVSLHTGLPVAACDVGDVGPELTVRLAAGDEVYLPLGAPLTPEQPEPGEVIYADGLGRAHSRRWNWRQSDLIKADVGFRRLLITVEAVHDGGRTDVEAALVRLRELLEDRVEALPGPVVLDRSNPTASLFAAELPQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY5</accession>
    <name>C7QBY5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792333.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3702"/>
    <dbReference type="EnsemblBacteria" id="ACU72604">
        <property type="protein sequence ID" value="ACU72604"/>
        <property type="gene ID" value="Caci_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3702"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="101"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="36289" checksum="36A53401B4ABB668" modified="2009-10-13" version="1">MAEQVLLGPGNQSLPRSPAGGPRAPQRRFVLNLRRNLAGYGFMAGAVLCFALFSWYPMIREFIMSFQGTHRDPVTRLPRTTWVGWRNYTRIFHDPTFAAAWKNTVEFSLLALLIGFAVPFVVAIVLNELRHARGYLRVLVYLPVMLPPASALLLFQYFYDPNVGLFDHLLHLVHLPTSQFVQSSGSAMVSVVIASTWMNMGGTTLIYLAALQNIPGELYEAAELDGAGVLGRIRHVTIPQTRLILSMMLMLQIVGTMQLFIEPFILTNGGAGPDNSTISVVNLIYQYAFNLSGSSNYNSASALGVLLMLVLGVFSALYLWISRDRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC51</accession>
    <name>C7QC51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_5640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794228.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5640"/>
    <dbReference type="EnsemblBacteria" id="ACU74499">
        <property type="protein sequence ID" value="ACU74499"/>
        <property type="gene ID" value="Caci_5640"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5640"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056335_0_0_11"/>
    <dbReference type="OMA" id="DEYPDAW"/>
    <dbReference type="OrthoDB" id="1707650at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="140"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="36021" checksum="B6DC3BB17078DF7C" modified="2009-10-13" version="1" precursor="true">MTAVLLLVVYALAVAVLAPPLLARHWPSDRAPRLTVTLLQILTCSFLLATVGAGLALAFTLVEGLSELSPALDSCADQLPVTDHGSLGTALGHLGWISAVLLSARLLYCLTATFGTAHRRRREHSQMLRMLAKRDDDLGVLVLDHPSPACYCLPDDVVITTGALERLSAKQLEAVLLHERAHMSGRHHLIIALATAIRRTMPHIKLLAYAERETRRLVELIADDAAVARTGAPTVAAALAVIGTAHAEDAPPEYNPVPETALAIDSSPTLRRIRRLLRLDQTLTRRTHALVIAATTAATVLPVALLAVSGATLFRPCPPDLDSGWSPAVVMSVAADGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCD3</accession>
    <name>C7QCD3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisF</name>
        <name evidence="11" type="ordered locus">Caci_5723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5723"/>
    <dbReference type="EnsemblBacteria" id="ACU74581">
        <property type="protein sequence ID" value="ACU74581"/>
        <property type="gene ID" value="Caci_5723"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5723"/>
    <dbReference type="eggNOG" id="COG0107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_4_0_11"/>
    <dbReference type="OMA" id="IFHYKET"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="26872" checksum="C572DB8465984086" modified="2009-10-13" version="1">MSTAALGRLAVRVIPCLDVDAGRVVKGVNFENLRDAGDPVELARAYDAAGADELTFLDVTASSDARATVYEVVGRTADQVFIPLTVGGGVRTVQDVDRLLRAGADKVGVNTAAVTRPELIAEIADRFGNQVLVLSVDARRCPEGVGTDSGFEVTTHGGRRSTGVDAVAWAARAAELGAGEILLNSIDADGMKQGFDLEMLAAVRAAVTVPLIASGGAGATEHFAPAVGAGADAVLAASVFHFGDVTIGEVKDSLRGAGYPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCJ9</accession>
    <name>C7QCJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7638"/>
    <dbReference type="EnsemblBacteria" id="ACU76462">
        <property type="protein sequence ID" value="ACU76462"/>
        <property type="gene ID" value="Caci_7638"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7638"/>
    <dbReference type="HOGENOM" id="CLU_3078029_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982745" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="52" mass="5279" checksum="8E8532254FA51E40" modified="2009-10-13" version="1" precursor="true">MSRFKHVLMGSVLAALVAVPVVPVLAQQTPTSNSTVTAALITPACAGCWAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCU9</accession>
    <name>C7QCU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785953.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1738"/>
    <dbReference type="EnsemblBacteria" id="ACU70659">
        <property type="protein sequence ID" value="ACU70659"/>
        <property type="gene ID" value="Caci_1738"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1738"/>
    <dbReference type="HOGENOM" id="CLU_1154776_0_0_11"/>
    <dbReference type="OMA" id="MVTCIVT"/>
    <dbReference type="OrthoDB" id="1877572at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="26313" checksum="DBFB25902A0ADF87" modified="2009-10-13" version="1" precursor="true">MAAVLLIFFGFIVALGVAGAVANSRRKRALAAMASAKQWQLTKKDRRLPDTFGGRPFATGHDRIARIVLNGWHNGHAILVIDYEYKTPASTSHQVMPGSDSPYMTPGNNSDDTHNYWAACVVDLPVPLPAVEVVPRKRHASHAAGPGILAGAPEFVRGDPGFDQRYLVTTLNQQLAADILDPKVLWLIASWPDFAWRIEGTRLLTWGKGKVKPVWVETSLNMLVALAEAFPAEVWRTARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY2</accession>
    <name>C7QCY2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785986.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1771"/>
    <dbReference type="EnsemblBacteria" id="ACU70692">
        <property type="protein sequence ID" value="ACU70692"/>
        <property type="gene ID" value="Caci_1771"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1771"/>
    <dbReference type="eggNOG" id="ENOG5032TBF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106738_1_1_11"/>
    <dbReference type="OMA" id="HQVTNAR"/>
    <dbReference type="OrthoDB" id="1736098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16940" checksum="D758DFAB214B9A02" modified="2009-10-13" version="1">MEPTITDLRDRLEIADALYRFGLGQDTQDAELFASAWTEDAELDFRPAAAKWGGAPPLMVGRDTIVTTILTGFAGRVDTTHQVTNVRAVVDGDTAHATALVEAQHLLTADHGTFALLKNPYSVELVREGSRWLIRRMRIENTWFTGDPVAIFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD15</accession>
    <name>C7QD15_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1804</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1804"/>
    <dbReference type="EnsemblBacteria" id="ACU70725">
        <property type="protein sequence ID" value="ACU70725"/>
        <property type="gene ID" value="Caci_1804"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1804"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_1_11"/>
    <dbReference type="OMA" id="YSAFSRM"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="33"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="30127" checksum="A1250D9930A96AE9" modified="2009-10-13" version="1">MTTADPSFLSTAPLTRLLLGRRAFGPMGGGKAGVLVERNLMVYRRLWLTMVSGFFEPVFYLLSIGVGLGKLTGAVDGVPYAHYVAPGLLAVSAMNGAVFDATFNVFFKIKYGKIYDAMLATPLRVGDIALGDIVWAQLRGLMYSAAFLLVMLVMGLVHSWWALLALPVTVLIGFAFAAVGMASTSFMRSWQDFDLVTLALMPMFLFSGAFYPLSVYNHQVRVLIEILPLYHGIDLLRALTLGRVHIGLLWDVLYLAAMGLIGAAVAARRLEKLLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD66</accession>
    <name>C7QD66_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal peptidase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3757"/>
    <dbReference type="EnsemblBacteria" id="ACU72659">
        <property type="protein sequence ID" value="ACU72659"/>
        <property type="gene ID" value="Caci_3757"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3757"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_10_0_11"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="3">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="3">
        <location>
            <begin position="131"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="18661" checksum="D6F3B9A1F45F1D03" modified="2009-10-13" version="1" precursor="true">MKPAMGLLESRSVFLTAAAAVSAIGVAGAVAALGARRALVLITVAGGSMSPTYADGEKLLVRRGRPRVGDVVVFRHPWLERTRQRATTMTETAAANATPRPDVDWMVKRVVATAGNRVPEDFRHAVAALDPDTMVPSGCLLVRGDNPRSLDSRHFGYVSTADVLGVALRRRPHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDB2</accession>
    <name>C7QDB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3804</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792434.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3804"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72705">
        <property type="protein sequence ID" value="ACU72705"/>
        <property type="gene ID" value="Caci_3804"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3804"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044209_0_0_11"/>
    <dbReference type="OMA" id="AFNQMWD"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983117" evidence="3">
        <location>
            <begin position="42"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="371"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="497" mass="52024" checksum="53D45EED20402746" modified="2009-10-13" version="1" precursor="true">MRSSSEHNPDRKSLAAKLRILAAGALAATSLVAAGQIPAHAATAAAASTSQFKGVNWADQRDNFVNGVLYPSGLNASDTHASASTVAAQVVGQLDTITGANTVRMPINEPTVSTYWSTYTGAIDAALTKGKVILAYWAYSGGKPTSTAAFNQMWDTVVASYGSNPNVYFEVINEPYGYSSTDLNNFYNTWLTRYPAVPRGQVILDGTGDATNIAGVAGDSRLANTLLAVHYYTFFAGTSTNESDWANGIANEIGSYASRTVATEWGAPMSPGSKNGVHYDTINYDVPGGNFFDAYVRGVSSELRKLGVGSVYWPGLRDGDWYSLTSKTGTGASIALTLVNASGLDRLQYAWGIGNGGGGGGTYDQIRDVATGLCVDGLGSTTVGTNASQSSCVTGDTNQEWTIVSSGGYVRIQNRATGLFLDGMGRTTNGSAAGQYSSSTSNNQQWTEVSTAGSARFQNRATGLYLDGMGRTSNGSDLGQYAGSTSTNQQWTLVSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDI3</accession>
    <name>C7QDI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792505.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3888"/>
    <dbReference type="EnsemblBacteria" id="ACU72776">
        <property type="protein sequence ID" value="ACU72776"/>
        <property type="gene ID" value="Caci_3888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3888"/>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022362_1_0_11"/>
    <dbReference type="OMA" id="CAIKRIA"/>
    <dbReference type="OrthoDB" id="1791095at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recombinase" evidence="1">
        <location>
            <begin position="203"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="54431" checksum="3D1FF7DAF6CDDB43" modified="2009-10-13" version="1">MSTPKLRLVPPVEQPADGLLRSWAQRNSDRTTPETPPAVGQLRFAFYGRVSTEDHQDPVSSRAWQRTRAEALIAGAGRITVEFFDVGRSRVLPWAARPAAAALIAALADPDREFDAIVVGEAERAFYGPQYEQMAPIFARHGVRVWVPDVGGPVDPEIGSLEELMALLGILSKREIVRARIRTVTSMTILTEKQGRFLGGRAPFGYRLVPIKPHPNPTHARWGRMQLGLAPDPTTAPIVEWMFAQRLAGMSYARIARALNDAHIPTPSAADRERNRHRAGLAWTVTSVAAILTNPRYTGHEVWQRTRTDHELIDPANTTLGHRDQVRHNRPDQWIISTDIAHTPLVSTADFIAVQGMRARPDAAKHEYLLAGLLICSACGRRMESCYANDHPGYRCRHGQNSATSPQNPRRLTYVREDRVLEHLAAMLIRLRMSEHTDDPPRRPIHEPATPTASETITFLRHNAITLTYNSDAKTLTANTPEKESIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDL1</accession>
    <name>C7QDL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Import inner membrane translocase subunit Tim44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5777"/>
    <dbReference type="EnsemblBacteria" id="ACU74635">
        <property type="protein sequence ID" value="ACU74635"/>
        <property type="gene ID" value="Caci_5777"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5777"/>
    <dbReference type="eggNOG" id="COG4395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_610712_0_0_11"/>
    <dbReference type="OMA" id="PVEYWTL"/>
    <dbReference type="OrthoDB" id="603937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983051" evidence="2">
        <location>
            <begin position="25"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Tim44" evidence="3">
        <location>
            <begin position="116"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="47480" checksum="9EF48D9E98A484F4" modified="2009-10-13" version="1" precursor="true">MRIGRRILVLAAVVALSSPAVAQARGGGGGHGFGGGGGGGGHGGGGGGFHGGGVGFVGGGGSVGVLLIVAVIVLIVWFAFKARSGNGVGSKRGLNTGSDRTAHRSDAAAAQRATQIEARVAAVADNDPTYAPEALKARAVWLYTTAQRAWSDRDRAVLKQILSPVLYVKWDEELRDYQSRGEINTVDIVSGPSVQMVNIANRAGEVNDTITFRITATLNDRVVRANGSHAVRKDGSTRPVEYWTLRKDASGEWMVASIEQAAEGAHHLTDAIETDVWDQKAVARDAVLEVAENVSVKGAGDILALTGISWSTDADAAAGDLSVLDGRFDKAVLEVAVEQFLEEWAMNDGSLDFTSVRTANRTVMRNAAVSAVEVRSLVSREPIVVRVVVEAEGFYYEVDRRTEEVLLGDAHKRRPVVFSFDLRLDGPTARGWTVVAAETSLPGSRIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDT7</accession>
    <name>C7QDT7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5853</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5853"/>
    <dbReference type="CAZy" id="CBM20">
        <property type="family name" value="Carbohydrate-Binding Module Family 20"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74711">
        <property type="protein sequence ID" value="ACU74711"/>
        <property type="gene ID" value="Caci_5853"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5853"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_3_11"/>
    <dbReference type="OMA" id="LDIVCNH"/>
    <dbReference type="OrthoDB" id="148706at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980876" description="Alpha-amylase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="7">
        <location>
            <begin position="639"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="742" mass="78541" checksum="13DCE3AB695C03D3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDZ7</accession>
    <name>C7QDZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_7761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7761"/>
    <dbReference type="EnsemblBacteria" id="ACU76585">
        <property type="protein sequence ID" value="ACU76585"/>
        <property type="gene ID" value="Caci_7761"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7761"/>
    <dbReference type="eggNOG" id="COG0750">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025778_1_2_11"/>
    <dbReference type="OMA" id="GPTQYNP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="9"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="43619" checksum="DD9A68DA9092F7F5" modified="2009-10-13" version="1">MGPLGIILFVIALVASIMLHEAGHMVSARKAGGKVTEYFVGFGPRIWSFRRGETEYGVKAIPAGGYVKIVGMTDLEPIEPEDEPRAFYHKPLGWRLLTLSAGSLVHFMIALLLLLLVPLTWGVRSQDLSGTVGNVTQCLKTTAGACAPGDAPSPARAAQLRNGDKIITVNGTHVTSWQDGPDSVTSLLHKGQPALGADNKPVSAPVPVEVTYVRDGQQHTTTITPSVGNISADPSKVQLGLMIGIQAPQLVWTHPGFANEVGNGFTTFGSFAKGSVTGLIDIPASIPKLFQATTSDKPRSADAPVGVVGMASLTGGVIQNSGYGGFLYYIASINMFIGIFNLLPLLPLDGGHIAIALYEAGRRKIAKAFGRPDPGRVDLNKLMPAAFTFLVLFVGLSLLLMAADITNPLKFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEH9</accession>
    <name>C7QEH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1950"/>
    <dbReference type="EnsemblBacteria" id="ACU70870">
        <property type="protein sequence ID" value="ACU70870"/>
        <property type="gene ID" value="Caci_1950"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1950"/>
    <dbReference type="eggNOG" id="COG0392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009723_0_0_11"/>
    <dbReference type="OMA" id="GYTHRRI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="665"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="746"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="773" mass="81013" checksum="B667D2DAFA7977AD" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QES7</accession>
    <name>C7QES7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792576.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3970"/>
    <dbReference type="EnsemblBacteria" id="ACU72847">
        <property type="protein sequence ID" value="ACU72847"/>
        <property type="gene ID" value="Caci_3970"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3970"/>
    <dbReference type="eggNOG" id="COG1479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507805_0_0_11"/>
    <dbReference type="OrthoDB" id="1939267at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="536" mass="58328" checksum="84E84CCB3CA860F8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF19</accession>
    <name>C7QF19_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5919"/>
    <dbReference type="EnsemblBacteria" id="ACU74777">
        <property type="protein sequence ID" value="ACU74777"/>
        <property type="gene ID" value="Caci_5919"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5919"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_3_11"/>
    <dbReference type="OMA" id="YPQDAQV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="13"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="40607" checksum="3D648A5566470EA2" modified="2009-10-13" version="1">MSAAASGSRPTSDVVVIGAGMIGAACAFYAARAGLSVTVVDSGPVAGGTSGAGEGNLLVSDKEPGPELDLALRSQELWRSLAAEDDGAFGAGFEFEAKGGLVVAFTATDFEALQRFAATQVPLGVVAEEVPGDRLAEFEPYIAPELAGGFWYPQDAQVMPALATARLLKASSARLRLGSAVTGLVLSGSGAVRGVRTVAGEIPARFVVNAAGFGASAIASFAGSALPVQPRRGFVLVTEPLPAMVRHKVYSAAYVADVSSSDAALQSSAVVEGTPSGPVLIGASRERVGLDRRPSYDALGRLAAQGAELFPFLADVKVQRYYTGFRPYLPDHLPAIGPDLNVSGLFHACGHEGAGIGLAPATGELIASMLIGQRSPVAAEPFAPARFGTAVEHGDGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFG7</accession>
    <name>C7QFG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796469.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7921"/>
    <dbReference type="EnsemblBacteria" id="ACU76744">
        <property type="protein sequence ID" value="ACU76744"/>
        <property type="gene ID" value="Caci_7921"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7921"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="WPAVQHN"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="107"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="36914" checksum="B115E5FC8755B205" modified="2009-10-13" version="1">MTDHELDPVTAGAPRAPRRRRVGRLSGRDKAVVAVLLGLPILIDLAFIWGPTLATVGLSFTKWNGVGGLSSKTCQPNVPSILNNGCLYGVQNYHQAATIYPEFWPAVRHNLIWLAVFVFFATPLGMLFAVLIDRGIKGSRMYQSILFLPVMLSLALVGIIWEFMYSQNYGLINTVIGHNHDTNAIDWLGNPKLNLWSVLVEASWRQAGYVMVLYLAGLKAVDPTLREAALMDGSNAWQTFWKVIFPVMRPINVVVMVVTVIESLRAFDLVYITNKGINGLELLSVLVTSNIVGETQRVGFGSALGVVLLVISLVPICTFLYLTFRRESQPKGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ2</accession>
    <name>C7QFQ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell cycle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0036"/>
    <dbReference type="EnsemblBacteria" id="ACU68991">
        <property type="protein sequence ID" value="ACU68991"/>
        <property type="gene ID" value="Caci_0036"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0036"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_3_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="490"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU68991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="659" mass="69923" checksum="E75BF6D7F78408B7" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFW4</accession>
    <name>C7QFW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786234.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2021"/>
    <dbReference type="EnsemblBacteria" id="ACU70941">
        <property type="protein sequence ID" value="ACU70941"/>
        <property type="gene ID" value="Caci_2021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2021"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_11"/>
    <dbReference type="OMA" id="PRFIITE"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="126"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="26031" checksum="BD238C40BDB48C33" modified="2009-10-13" version="1">MKRLLVVDDEAQLLVAVRINLSARGYEVSVAPDGTTGLAVAARRPPDLVVLDLGLPDMDGVQVIDGLRGWTTVPILVLSGRTESWDKVEALDAGADDFVTKPFDMDELAARVRSLLRRAEPENATGPVIQVGHHLVDLAARTVKRAPGAPSDVPESVRLTRTEWAVLEMLLRHPDRLVSSKQLLAHVWGTEHEPEGSYLRFYLARLRQKLEPEPSTPRQLLTEPGMGYRFQPLGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFX7</accession>
    <name>C7QFX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-NAD/AcoX kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2034"/>
    <dbReference type="EnsemblBacteria" id="ACU70954">
        <property type="protein sequence ID" value="ACU70954"/>
        <property type="gene ID" value="Caci_2034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2034"/>
    <dbReference type="eggNOG" id="COG3199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064691_0_0_11"/>
    <dbReference type="OMA" id="RGNQQFS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039065">
        <property type="entry name" value="AcoX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40697">
        <property type="entry name" value="PTHR40697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="30315" checksum="EB4BE3E72E9B2E09" modified="2009-10-13" version="1">MGEVAARAGGFVPEVVWAAGVPSSAADTVAAARVLASRVDLLLFAGGDGTARDVLEAVGDSVPVLGIPTGVKMHSAVFAVNPRAAGEVAAGYSRLRDAEVVDRVDGSPRLFGYLRVPDVPARVQQRKIGSSGVSPEAVSGIAAELRSMVMPGELLVLGPGTTTRAIAAVWGLDVPALGVNVIDGEKVVAADVGADELLELVSGAAAHIVLTPIGGQGFLLGRGNQQLSPEVLRAVGLEWLHVVASEAKVVALGGRPLLVDTGDDSLDRAFPRYVRVVTGWRRTILYPLNERQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG98</accession>
    <name>C7QG98_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4078"/>
    <dbReference type="EnsemblBacteria" id="ACU72943">
        <property type="protein sequence ID" value="ACU72943"/>
        <property type="gene ID" value="Caci_4078"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4078"/>
    <dbReference type="eggNOG" id="ENOG50336WS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058041_0_0_11"/>
    <dbReference type="OMA" id="WWSEART"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025855">
        <property type="entry name" value="Replic_Relax"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13814">
        <property type="entry name" value="Replic_Relax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37112" checksum="614A1E0678023B6C" modified="2009-10-13" version="1" precursor="true">MTPAVPNPSPPAHPDYLPAAVIRDPAPAARRAALAELAARLTARDRWLLHALREHQVLTGPQIARIAFDGPRIANRRLAILANELRVIERFRPLRAIGSAPEHYVLGAHGAQVLAAEAGVTIKQLGYHRSRSLGVAYSPRLAHTVGVNEVYSHLAAASRIGPDADGELVSWWSELTCFHLYGDLARPDAFGRWKAPAPRGKLRTAEFFLEYDTGSENLERVVGKLDGYARLAAVTGIDTPVLFWLQSPNRERALHRMLALDPPTVPVATATPAATEDTTPAGPVWELAARTARRLHLIELAAYASAAGHATADRDADAARTGRLFNPPNPLPPDATGKEHSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGI9</accession>
    <name>C7QGI9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4365 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794598.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6012"/>
    <dbReference type="EnsemblBacteria" id="ACU74869">
        <property type="protein sequence ID" value="ACU74869"/>
        <property type="gene ID" value="Caci_6012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6012"/>
    <dbReference type="eggNOG" id="ENOG50338W3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114899_0_0_11"/>
    <dbReference type="OMA" id="AQVKSWS"/>
    <dbReference type="OrthoDB" id="1455772at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025375">
        <property type="entry name" value="DUF4365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14280">
        <property type="entry name" value="DUF4365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4365" evidence="2">
        <location>
            <begin position="34"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="21652" checksum="97CDE308DFA7309F" modified="2009-10-13" version="1">MTGTIDQGFQANENKTGGAGRPLTLGDSGHQGDFGETFIRALAAAANLDALRSDRDRVGVDWTLRYPAVNGRRGFPLIDAQVKSWSDPRGNDVAWRYPLEVKNFNWLAGRDYLVPRFLFLVVVPRASAAWTDITPDRLILRHAAYWACFHDALPLPGRNRSSTYTVRVPRANLLDIRALHGLFGDEFREMLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS0</accession>
    <name>C7QGS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794679.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6095"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ACU74950">
        <property type="protein sequence ID" value="ACU74950"/>
        <property type="gene ID" value="Caci_6095"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6095"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_2_11"/>
    <dbReference type="OMA" id="GYAMQFQ"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982872" evidence="3">
        <location>
            <begin position="45"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="252"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="38798" checksum="00B28AA6352D0A13" modified="2009-10-13" version="1" precursor="true">MAHHSTKRSKRHRAATPPARGRTVAAAALTAVAAAAGVCGTAAAAPAAGPGSGASDTDRGTVKAQIAALYRQADQLTQTFDAAQEQESALSLAVQRSQSKLQTMQADYEHQRAAIGAIAANQYRAGGVDQRLALMLADHPETFLGNEAMATRVSDQQSRKVAEVIEERRQIVQLQRAAADQLSALNQTRDTAARSRTQVTEQLHKAQSLLNTLSAPQRRAAIQADLGADPASPFTGEQPDPNTPDQNLPAPSDRARAAIEAAIADLGKPYVFGAEGPDAFDCSGLIQQAWRQAGVELPRTSSEQAQAGQQIPLSQIQPGDLVIYYAGRSHIGMYVGDGKIIHAPHPGTQVRYAPLMSMPVNMVVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHA0</accession>
    <name>C7QHA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784334.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0084"/>
    <dbReference type="EnsemblBacteria" id="ACU69039">
        <property type="protein sequence ID" value="ACU69039"/>
        <property type="gene ID" value="Caci_0084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0084"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_7_1_11"/>
    <dbReference type="OMA" id="IVCPERT"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="16789" checksum="90084A4DED9AA628" modified="2009-10-13" version="1">MASKNPFLPLTEETPVYVISVAAQLAGMHPQTLRQYDRLGIVCPERTGGGGRRYSARDIDTLREVQRLSQDEGVNLAGIKRIRELEEQVAALSRRVAELEAVTLYPTAKGTVPVAAPIAPPVSPLPPAPPGYRGDLLPALPATFTTALAVWKPQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHD6</accession>
    <name>C7QHD6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784370.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0120"/>
    <dbReference type="EnsemblBacteria" id="ACU69075">
        <property type="protein sequence ID" value="ACU69075"/>
        <property type="gene ID" value="Caci_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0120"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140387_0_0_11"/>
    <dbReference type="OMA" id="RGGCWFR"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="12736" checksum="3B8EB11F4B46947E" modified="2009-10-13" version="1">MLAALHHAQVAVPKGAEDVSRAYYVGVLGMTELPKPPVLAARGGCWFAAGGLEIHTGVEEPFIPARKAHPAILVTDIDELAAALTAAGHEVAWDQTIPDKRRLHTFDPHGNRLEFIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHK0</accession>
    <name>C7QHK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786318.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2106"/>
    <dbReference type="EnsemblBacteria" id="ACU71025">
        <property type="protein sequence ID" value="ACU71025"/>
        <property type="gene ID" value="Caci_2106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2106"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_4_1_11"/>
    <dbReference type="OMA" id="GHGWYSA"/>
    <dbReference type="OrthoDB" id="1213908at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_2" evidence="3">
        <location>
            <begin position="148"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="37837" checksum="31AD8C4714633179" modified="2009-10-13" version="1">MRLALRGGNPLERAALRANLVPTPAAEAWGGVAASGVLVAAVRTGVIARLASAPGTPEEIARDLCLAPAPTRLLLDCLISTGHARRSRDGSVRLARRDRRWLDPESEVGVARFVNACGDYFDWWRDLDRVIETGASVEHHDHGPDDPYWRRYVLGQLDLARLSAAEVARRLVLPRDAGSVLDVGGGHGWYSATLCRRHPGLTATVLDLPGSARVGREVIEAAGLAHRVTFVEGDARTAEFPGGQDAVLLFNLLHHLAEGEIPALFARAAEALKPGGTVVVLDGFAEPPRPGRARGNAAATHLALFVRLTSGSTVYTPADLRSWLHGAGFGDPRRVRSARIPGLALHQAWRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHK8</accession>
    <name>C7QHK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2114"/>
    <dbReference type="EnsemblBacteria" id="ACU71033">
        <property type="protein sequence ID" value="ACU71033"/>
        <property type="gene ID" value="Caci_2114"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2114"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="GFITMPG"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="28996" checksum="11C4F16933EAEB9B" modified="2009-10-13" version="1">MVDMTNASDTPRRWFITGANSGFGLALVHAALSAGDEVVAAVRRPETMADLVAASGGRVSVVELDLGDRDRLRAAVEAAGRIDILVNNAGFGIVGAIEETSEAELRNAMEVMFFGPLELTRLVLPQMRARRAGTVVQLTSMGGMLAFPGVGAYCAAKGALELASEALAGEVAPLGINVLIVEPGAFRTGFAAPAALQAVDARIADYDGTAGATRDGLPTSHGAQEGDPVKAAAAVLEVLGWKEPPLRLALGNDAVDEIRRKLASVGADLDATEHLGRAMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ9</accession>
    <name>C7QHQ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786377.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2165"/>
    <dbReference type="EnsemblBacteria" id="ACU71084">
        <property type="protein sequence ID" value="ACU71084"/>
        <property type="gene ID" value="Caci_2165"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2165"/>
    <dbReference type="eggNOG" id="COG4315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053665_0_2_11"/>
    <dbReference type="OMA" id="CAEIWPP"/>
    <dbReference type="OrthoDB" id="1797023at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005297">
        <property type="entry name" value="Lipoprotein_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03640">
        <property type="entry name" value="Lipoprotein_15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982889" evidence="2">
        <location>
            <begin position="38"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="17780" checksum="6F9C64A936E2317C" modified="2009-10-13" version="1" precursor="true">MVKPGIPPTARVAGVVSAVALLALASACSSSSGKSNSASSSAPPSSSSMSGTAGPTITSASASVSGAQTMVLTAPDGHTLYYFTPDTAGGMPTCTGACASVWPGLTATSPTAASGVTGKLTVVSGHVVYNGHPLYEYSGDSAAGQAKGEGIGGTWYVATPTLAVGAGPASTPAPSSSSTSGGGSGGGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHY5</accession>
    <name>C7QHY5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4166"/>
    <dbReference type="EnsemblBacteria" id="ACU73030">
        <property type="protein sequence ID" value="ACU73030"/>
        <property type="gene ID" value="Caci_4166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4166"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_415999_0_0_11"/>
    <dbReference type="OMA" id="WGREASE"/>
    <dbReference type="OrthoDB" id="968199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="738" mass="77791" checksum="EC9A388029F1B637" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI14</accession>
    <name>C7QI14_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792788.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4195"/>
    <dbReference type="EnsemblBacteria" id="ACU73059">
        <property type="protein sequence ID" value="ACU73059"/>
        <property type="gene ID" value="Caci_4195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4195"/>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="AVQLQHI"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="378"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="592" mass="63093" checksum="58F5FA3BC8BCED50" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI24</accession>
    <name>C7QI24_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lantibiotic dehydratase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792798.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4205"/>
    <dbReference type="EnsemblBacteria" id="ACU73069">
        <property type="protein sequence ID" value="ACU73069"/>
        <property type="gene ID" value="Caci_4205"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4205"/>
    <dbReference type="eggNOG" id="ENOG502Z8P5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013885_0_0_11"/>
    <dbReference type="OMA" id="NSWHAAT"/>
    <dbReference type="OrthoDB" id="1406236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006827">
        <property type="entry name" value="Lant_deHydtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04738">
        <property type="entry name" value="Lant_dehydr_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="752"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Lant_dehydr_N" evidence="2">
        <location>
            <begin position="156"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Lant_dehydr_N" evidence="2">
        <location>
            <begin position="596"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="937" mass="103104" checksum="9B844E852683FA4E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB5</accession>
    <name>C7QIB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794721.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6138"/>
    <dbReference type="EnsemblBacteria" id="ACU74992">
        <property type="protein sequence ID" value="ACU74992"/>
        <property type="gene ID" value="Caci_6138"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6138"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1650717_0_0_11"/>
    <dbReference type="OMA" id="YLEMNGS"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="18733" checksum="0CF6D2D7FF90EC2E" modified="2009-10-13" version="1">MEQHQITEILNRPYSQELLARDLTRLAYVAEDGTPRCVPIAFTWNGSQVVLCTTKNAPKLPALRQNPQVALTIDTEVHPPKILLMRGTAELDEVDGIPEEYLRMNGTYDMTPEQRVEWEAEIRSLYDGMVRVVITPTWAKLIDFETTLPSAVEELVQARAERQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ5</accession>
    <name>C7QIJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794801.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6218"/>
    <dbReference type="EnsemblBacteria" id="ACU75072">
        <property type="protein sequence ID" value="ACU75072"/>
        <property type="gene ID" value="Caci_6218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6218"/>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123922_0_0_11"/>
    <dbReference type="OMA" id="GPWVQID"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019920">
        <property type="entry name" value="F420-binding_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03618">
        <property type="entry name" value="Rv1155_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="14"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="17172" checksum="F71A46BB2EFCC5B9" modified="2009-10-13" version="1">MPRTIATNTSVDLDALLEFVRPRHRALLITRRADGSPQASPLTCGVDDDGRLVMSTYPERAKTTNARRDTAVSVVILSDEWNGPWVQIDGEAEVLDIPDSVEPLVEYFRTISGEHPDWDEYREAMVKQGKSLIRVTPRRWGPVATGGFPARLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM1</accession>
    <name>C7QIM1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6244"/>
    <dbReference type="EnsemblBacteria" id="ACU75098">
        <property type="protein sequence ID" value="ACU75098"/>
        <property type="gene ID" value="Caci_6244"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6244"/>
    <dbReference type="eggNOG" id="COG1832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112567_0_0_11"/>
    <dbReference type="OMA" id="IEHARFH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="33"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="19195" checksum="4D4B263181EA0D9C" modified="2009-10-13" version="1">MSGLGEVSGVGDVGGVSDGVARYQDPTTIQRVLNTARTIAVVGLSKNELRASYFVGYYLKRHGFRVVPVNPRETEILGERCYPSLRDIPEPVDVVDVFRASDAVPGVAREAVEIGASALWCQFGVINPEGNQIAENGGLSVVVDRCIKIEHARYVGRMHWLGFNTHRITSVRTGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIW2</accession>
    <name>C7QIW2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8189"/>
    <dbReference type="EnsemblBacteria" id="ACU77012">
        <property type="protein sequence ID" value="ACU77012"/>
        <property type="gene ID" value="Caci_8189"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8189"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533911_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="510" mass="51601" checksum="0C27DF8D3F747E25" modified="2009-10-13" version="1" precursor="true">MRSVLSRLTTPGPLLALGLGVTTVAASLWFATANRALTSHSAVTLYSFYFLVGTIGTGVLAGLEQEMTRTVARTHAAGRPVGAAVRGQLRQAAGLAVLTVLILSAASPLLVSHWFAGDWTLALALLAGLAATWASFLVRGVLAGCQDFRYYSLTLVVQGVATIAPSVVLALAGPGHMLGYALIFALAPLVAAVSGLASPALRRSWRATGTAADIPAGAAALSEESIAAGDGAGAQPTSATPDTPGAPVAADTGEESGEEPGGSPREKLLLLTLATLVSQLLINAVPLVIAHRLAGGDAHSVDLGKSLSSSMGFSRLALLCLFPLQAPLLPLLAAAAVRGDFREVRRKTGFLVTACLVAGALGVVAVVAAGPWLLTDYLHAPAQLSHLFLSALALSTAFLMTAFVLQSAQVALNRHRVVFASWLAGLAAMALVFALPVSPLAAAGWAGILGPLVVTLIAGADVMFVTRAQPTVTASADGAADAVPVPVAEAAAGESRSTGQAAPVAEGVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJL6</accession>
    <name>C7QJL6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uroporphyrin-III C-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_2321</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2321"/>
    <dbReference type="EnsemblBacteria" id="ACU71239">
        <property type="protein sequence ID" value="ACU71239"/>
        <property type="gene ID" value="Caci_2321"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2321"/>
    <dbReference type="eggNOG" id="COG0007">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_1_0_11"/>
    <dbReference type="OMA" id="GRFMAQE"/>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012409">
        <property type="entry name" value="Sirohaem_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036426">
        <property type="entry name" value="Sirohaem_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="14">
        <location>
            <begin position="170"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036426-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU71239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="41738" checksum="1258E75E1C957D00" modified="2009-10-13" version="1">MSAMTDPAPVYPAALRLAGRRVVVIGGGPVAQRRVLGLLDARADVLVVAPEATPAIEALADGGEIVWEPRPYRDGDLAQAWYAVAAADDPAVNGAVAREAEAGRVFCSRADSAEDSTAWTPAVGRHDGVTVAVIGGGDPRRAVDVRDGVLEGLRDGTLAAPHHRGRTPGVALVGGGPGDPDLITVRGRRLLAEADVVVADRLGPRGLLDELAPDVEIVDASKIPYGRSLAQEAINELLIERAKAGKFVVRLKGGDPFVFGRGFEEVLACAEAGVPCSVVPGITSSISVPALAGIPVTHRGVAHEFTVVSGHVAPDNPKSLVDWAALGRMTGTLVILMGIERIAAIAETLLAHGRGPETPVAVIQEGTMPGERRVQTTLGMIGEAVAEAGIRPPAIVVVGPVVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJQ7</accession>
    <name>C7QJQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4281"/>
    <dbReference type="EnsemblBacteria" id="ACU73145">
        <property type="protein sequence ID" value="ACU73145"/>
        <property type="gene ID" value="Caci_4281"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4281"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_701665_0_0_11"/>
    <dbReference type="OMA" id="TEAHVTI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="42122" checksum="D4478FC966298FF1" modified="2009-10-13" version="1">METPVTAGVEDGLHIERHVGAVLTAVAVTARAVALVSAVISLVVGLQERQFAHARLAVVAYVAVGLWSLIYLARARGGPPALWASTIDIAVLAAAMPALRVAGRPGYFDNVSNSALEPFVSAVLVGVAIHASTRRTLVACAVLGASYLATVTTHLSVVKVTNAGGDLAWLIGIALVCLVGARRLHRAAAAVGAGARSVVTEREQLAEDRGRDLERRRQLEGQRRRHLELHDGPLALLTAMSRPAPVGHPDARVRERCAANADLLRGLLSEEDDTGCESVPELRLGLVGAGADCAALGLRVRFQFGSLPAQVPEPVVEAMCGATRAALNNVLAHAGTRTAWVTVDAAADNAEAVTVDIVDCGSGFDPGTTAAGVGLPAAIGGRMAEVGGAAGVDSVPGNGTWVRLRWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK23</accession>
    <name>C7QK23_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4397"/>
    <dbReference type="EnsemblBacteria" id="ACU73261">
        <property type="protein sequence ID" value="ACU73261"/>
        <property type="gene ID" value="Caci_4397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4397"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016564_0_0_11"/>
    <dbReference type="OMA" id="RYANMES"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="466"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="687" mass="73529" checksum="B83744B6A41E1A41" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK42</accession>
    <name>C7QK42_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-L-arabinofuranosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794845.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6262"/>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75116">
        <property type="protein sequence ID" value="ACU75116"/>
        <property type="gene ID" value="Caci_6262"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6262"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030937_0_0_11"/>
    <dbReference type="OrthoDB" id="620389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981067" evidence="1">
        <location>
            <begin position="34"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="50846" checksum="B50F91831FAD3FB5" modified="2009-10-13" version="1" precursor="true">MFKNAYGTMFSLLAATTTLSGATNLSSATPASATSASAVHVDVSANDVITRLGDHAVGVNTPIWSANLLDRPADRLIRDAGIQRLAFDGGGVSDLYHWRTGRLSPDPQAAAHDAQGLDYEDLKPQFSFDQFAATARATDSSMLVHVNYGTGTPQEAADWVRYANKTRHYGVTDWAIGEETYFNGALGASMNTEPDGHADKSAQAYATNSLAFIKAMKAADPSIRVGLELAAPIPGTPMLDWDKTVLSVAGSAADFVDVHYYTGAQTDAALLASPQTSIPRGMASLRSLVASYNPKLKIDIGETNSYYQQAPQQISPTNALYLPESVLAMLENGAGEVDWWSLYNKWGGSAESGYGDLGLLASGNVSGDGASQGPKADTKFDPYYGMQLLGALARPGARLVTATAGGSVVAHAALLPDSGLGVLLANNDPDHAAPIDTRINGFHAGSKATILTYSAATHRVTETHGSIPKTLPAYSLTLVLLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL8</accession>
    <name>C7QKL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8294"/>
    <dbReference type="EnsemblBacteria" id="ACU77117">
        <property type="protein sequence ID" value="ACU77117"/>
        <property type="gene ID" value="Caci_8294"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8294"/>
    <dbReference type="eggNOG" id="ENOG5033XVZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2105723_0_0_11"/>
    <dbReference type="OMA" id="GNEARVM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="12788" checksum="7DBF6C2AF3897DD3" modified="2009-10-13" version="1">MSALQALHGAAHTVATFLMDPAPTPAPPSGGNDINTIIGGIAPNWGPFGKVGNEARVMVEVVMATAILLCLGIAVWGAAKQRIGATALRDTFSAEQGRGLIVAGLTGVFIIGSLGTLFTIVYGMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVC4</accession>
    <name>C7PVC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0327</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0327"/>
    <dbReference type="EnsemblBacteria" id="ACU69280">
        <property type="protein sequence ID" value="ACU69280"/>
        <property type="gene ID" value="Caci_0327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0327"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_1_1_11"/>
    <dbReference type="OMA" id="AHSGRWY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="36655" checksum="0B3BFD9F6CC02680" modified="2009-10-13" version="1">MNHPAGRVLTLLELLQSGGVRTAAEIAERLGVDARTVRRYVEQLLELEIPVESVRGRYGGYRLARGFRLPPLMLGDDEALAVLLGLLAGRRSGLTAALGAAGETAGAKIRRVLPARLSERLRSVLDSVAFTGAPDQSAALDATVLLTVADAVANQRPIAVRYTGRDGVRGDRTLHPYAIVSHGERWYVRALDPAIGEERTFRLDRIDGARALPGSFEAPTMDDDPGQSLLAGFAAADYRYEVAIRVHGTVEQIRARFPVSVATIQPLSDANGNGDGNGNGNEAQTPWHRLAIRAEHLDWIPPTLAALDLPFEIEDPDELRDLVIAFADRLATRARGGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ7</accession>
    <name>C7PVJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69353">
        <property type="protein sequence ID" value="ACU69353"/>
        <property type="gene ID" value="Caci_0401"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0401"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="EFFEYAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="27042" checksum="3BF5E96A8CE2C493" modified="2009-10-13" version="1">MTNAKTEMAKPQVAAPAAPRPLRRDAERNRQLIIDTAKTVFAARGLDASLDEVAHEAGLGVGTVYRRFPNRDALIDALFDDMLASITRIVAESMALPRAWDGLVHFMTAMLESQGRDKALRDLMLSRQKYLDQCELDREEVVRETVQPALYDIIGRAKAEGDLRPDVVPADVGVLLISAVGVVDFTAPADPEVWRRHLAVLLDGLRARAAGDTTVLAPAPLDDEQLDLCMSGWKYGTRETPRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVK2</accession>
    <name>C7PVK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MgtC/SapB transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784653.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0406"/>
    <dbReference type="EnsemblBacteria" id="ACU69358">
        <property type="protein sequence ID" value="ACU69358"/>
        <property type="gene ID" value="Caci_0406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0406"/>
    <dbReference type="eggNOG" id="COG1285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079292_0_1_11"/>
    <dbReference type="OMA" id="VTVTAMH"/>
    <dbReference type="OrthoDB" id="2022224at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="26488" checksum="4E213638711DC1E3" modified="2009-10-13" version="1">MSASILWEEPTGQGWTQVGELTTALVLSSAIGLEREIRQKAAGLRTYTIIGLGAALFMLVSKYGFTDVLRPGLVQLDPSRVAAQIVSGLGFIGGGVIFMRRDSVRGLTTAAAMWLTAGVGAAAGAGLGLLALLTTVAYFVVCYGLRPLTHWMPALRTPPVTYRIEYQDGRGLLRTILDICTGAGFFVASFSGTGHDERDAQREPGAHPHTVEVVLTLHGRGNANALTEQLVDTSGIVAVAYNHEDDEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM6</accession>
    <name>C7PVM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0430"/>
    <dbReference type="EnsemblBacteria" id="ACU69382">
        <property type="protein sequence ID" value="ACU69382"/>
        <property type="gene ID" value="Caci_0430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0430"/>
    <dbReference type="HOGENOM" id="CLU_1183299_0_0_11"/>
    <dbReference type="OMA" id="GAFQRIR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="22818" checksum="3129FE59B23F540E" modified="2009-10-13" version="1">MITLIEPADDDDDAVTGDQGGVGGVGGARGSGGDGDSDSDSFGYSIEGDDGDGDELVVLLRPGVSVLAPPAGAFQRIRRRAARRRLARAAATVGAGAAMAAVAVTVALWPSNSALGPPAPVSPVAPPVQRTSIPDAPATTPLTSSSPSPSPSSLPSSSPSPTPQRPHAGPSDSAAPPTAPPSTAVRTAPTRVPTTRPATAATPSTPPRTEGSVTPEGSATPAGRATPTCPSGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW10</accession>
    <name>C7PW10_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycolate oxidase iron-sulfur subunit</fullName>
            <ecNumber evidence="4">1.1.99.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2484</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-lactate + A = AH2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15089"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>A + glycolate = AH2 + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:21264"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="1.1.99.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 2 [4Fe-4S] clusters.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.14" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2484"/>
    <dbReference type="EnsemblBacteria" id="ACU71402">
        <property type="protein sequence ID" value="ACU71402"/>
        <property type="gene ID" value="Caci_2484"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2484"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023081_0_1_11"/>
    <dbReference type="OMA" id="CGLCLPH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012257">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32479:SF17">
        <property type="entry name" value="PTHR32479:SF17"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000139">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="384" mass="41607" checksum="582A399FB0C6A08D" modified="2009-10-13" version="1">MSEDTSRREMPESEPAGIFSKDLLDACISCGFCLPACPTYALTGQEQSSPRGRITLMRLLETGDLAADDPTLAEEASLCLGCRACETVCPAGVQYGHLLEEWRDEQWSGLKRPWIVRPLLLVANRKWVLRLLGLVRRSARKRSGSSSSSSGTSDQPTLMLGCFERALFPSVSRNIAALDPNLTVDPDQGCCGALHAHNGDLDQGRDLARKLGEQLPGTIVTTSGGCAAHLADVIGRDRVVEASEWLLKQDTATAQNTAVARSTATEQRPLRVGLQDSCHLRNGLGVWREPRELLGRTATYVELPSAGSCCGAAGTYALVRKKESKAILAKKIAEIEAADLDLVIAVNPGCLRQLQTGLRKAKSRTKAVHIVDYQRGDYRRGDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH6</accession>
    <name>C7PWH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6402"/>
    <dbReference type="EnsemblBacteria" id="ACU75256">
        <property type="protein sequence ID" value="ACU75256"/>
        <property type="gene ID" value="Caci_6402"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6402"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037308_0_0_11"/>
    <dbReference type="OMA" id="RFVCGTE"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047091">
        <property type="term" value="F:L-lysine 6-monooxygenase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="43139" checksum="DF53A05CEABECBCB" modified="2009-10-13" version="1">MTGIEILDTAVVGAGPYGLSVAAHAKARGSRTRVFGTPMRAWAEHMPLGMKLKSEPWASHLSDPRDKYTLKEYCRIEGLPYGHGIPTPVETFVAYGRWFREQTAPDLHETDVVRVDREGSAFALQLADGSSVRSRSVVLATGFLPFPRFPEALAGLGAPQVLHSSAVNDLSGFAGKQVTVVGAGQAAIEISVLLDEAGADVTLVARTGALAWNSLPGDLPSTLWQRLRKPENGLGPGYYNLVLGDLPAVFRRLPAGYRMEVVRKTLGPEGSWWVRERFEKSFDTEHIRIGTRITSAKPDGDALLLELSDGRELKTDHVIAATGFEVDVRNLTMLGEELRRRVRGMRGSYGPPMLGAGFDSSVPGLHLVGLASAATFGPSMRFVFGSAFAARTVAPRLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY2</accession>
    <name>C7PWY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77239">
        <property type="protein sequence ID" value="ACU77239"/>
        <property type="gene ID" value="Caci_8416"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8416"/>
    <dbReference type="HOGENOM" id="CLU_586225_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980417" evidence="3">
        <location>
            <begin position="28"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="46282" checksum="1EB178437590597A" modified="2009-10-13" version="1" precursor="true">MRRGLRAVVAGLMVVGAGTFAAGTAVAADGTGPVATPPSSPKTQTVSGVAANGVQLSMTAPAQLPLDLPDQQLPEREVDVTATDVGGQGYTGTVTMTLTSEGSSASASSLRLDHYDQASGAWQPESIPSGGSSFTVTDDVAVPANGTQVLKLRLSPGTKVVDDVKLSASANGATAVATMPVTGLSFQVTGLSGTARAGSPIVLTGTLTNPTDVSLRDVPVKLLLCSGGSAGCVSHASDVKVEAQSSTGAWRTVSVSDATATSPMSAMVVPQLTLPAGGTAQFSVRVTVGAGAFGTPGQPSSQPTDQPTSQPSSTAPAQPVSVAVALNALGLTFETQPTTSGTLTVQPPPQQPATPSTPSSTASSSTPSATPTTTDSPTPTTTPTATPSTTPTTTPASSTDAASTPDAATSSSNPTILVAAGLLAVCLALVLWWALMKRRERTAVAAAAHGDAEAHDDEYGTEHGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX83</accession>
    <name>C7PX83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0482"/>
    <dbReference type="EnsemblBacteria" id="ACU69434">
        <property type="protein sequence ID" value="ACU69434"/>
        <property type="gene ID" value="Caci_0482"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0482"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_4_11"/>
    <dbReference type="OMA" id="WINVASY"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="458" mass="47246" checksum="01AC33D7B325708F" modified="2009-10-13" version="1">MERGARVDGDSVPAESAGSGAAAPAERRAPEPKPEPEPEPADKRSVLRDHDFRALLASKSASTVASAVTWVVLPLYVYTVSRSSLLTAVASAMNVIPYVLFGIVAGALVDRSSPRRVMIVVELGNAAIMLTVPALHAGHVLSIAVLCAVGFTSATAFVWFDVASSTLVPSVVGKTAVFHANGFLWSVATLVQAVAAPTGFFLLNRWGIGWTFAALSLFYALSALFLAMVRMPSAASGGVAAGAPASAGGPGRAMLEGLQFIVREPTIRLLTIIGMGSGISAGAVYGMIVVFANRALHLGTDDYRISWILAASSAGALLASFAAPRLRGLPPIPSVAGLLVVDTVLMAGYALSADWQMALGAILLWNLAHTTLMIVSISLRQVLAPPRLQGRVNAAGKMLAWGSVPLGSALCGALTGWIGSRQASLLLVAPIAASLVLAAAMVVRRPAVTDPSKASESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX85</accession>
    <name>C7PX85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0484"/>
    <dbReference type="EnsemblBacteria" id="ACU69436">
        <property type="protein sequence ID" value="ACU69436"/>
        <property type="gene ID" value="Caci_0484"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0484"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023724_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980427" evidence="1">
        <location>
            <begin position="31"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="656" mass="66789" checksum="F18014CD35682979" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT1</accession>
    <name>C7PXT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793120.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4528"/>
    <dbReference type="EnsemblBacteria" id="ACU73391">
        <property type="protein sequence ID" value="ACU73391"/>
        <property type="gene ID" value="Caci_4528"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4528"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_17_3_11"/>
    <dbReference type="OMA" id="FNVPWFT"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="409" mass="42516" checksum="A971873C046314FB" modified="2009-10-13" version="1">MNPLREKPFRRFFLGQSISVTGGAATQIALCFAVLQITGSARDLSLVVSAQMIPTIALLLIGGGIGDRIGQALLLRVTHFGLGVTQGAMALCLLTKQPFGYLIALAFATGVLSAFAGPSLSGIVPQLVGPAGLQKANSLLASVRNAAMVLGPTLGGVLVSTIGGGWALVADSASFFVAGAMFCFVPVGDRPVLSDRKLFTELRQGWTYFRSSSWIWSMTAAFTVSGFLQMGAGQVLGLVLAKQTFGAEGWGVIISCRGAGQLIMSVLMIRVRVRRPLLVGQAVITLQAMPYLLLGLNAGVAAVAAASFVAGFGVTFASVAWDTSLHTYVPNAMMSRVVSYDQFGRSLAVPAGQLSIIPIADAFGTRHVMVATGVLFAVTMVAPLLLSSVRRVGTGDLDEAPDPAVAVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYE2</accession>
    <name>C7PYE2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795161.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6586"/>
    <dbReference type="EnsemblBacteria" id="ACU75432">
        <property type="protein sequence ID" value="ACU75432"/>
        <property type="gene ID" value="Caci_6586"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6586"/>
    <dbReference type="eggNOG" id="COG2321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059329_1_0_11"/>
    <dbReference type="OMA" id="ANANDDC"/>
    <dbReference type="OrthoDB" id="1175086at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30168">
        <property type="entry name" value="PTHR30168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="31021" checksum="19D7124F367CC2AA" modified="2009-10-13" version="1">MTFDPEAQLDTSDVRDERGGGGGFLGGGFPGGRGGIAGLIFALIAAAVGVPVATMGGGGNGNGGTSASPGGVDSSLAAKCHTGADANANDDCRVVAVVDSVQNYWSTAFANSGKTYQRAATVLFSGSTSTACGPATTQVGPFYCPGDRTVYLDLGFWQELRSQFGAKGGPFAQAYVVAHEYGHHIQDLQGTLGRAQQGGQGATGGSVRTELQADCYAGIWAHWATTTKDASGHPLIDALSQQNIADALDAASAVGDDRIQQETQGNVTPETWTHGSAAQRQKWFTTGYQTGDLKACDTFAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI6</accession>
    <name>C7PZI6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-L-arabinofuranosidase B catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2728</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2728"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH54">
        <property type="family name" value="Glycoside Hydrolase Family 54"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71643">
        <property type="protein sequence ID" value="ACU71643"/>
        <property type="gene ID" value="Caci_2728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2728"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029332_4_0_11"/>
    <dbReference type="OMA" id="WHNGASS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031221">
        <property type="term" value="P:arabinan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019566">
        <property type="term" value="P:arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="PTHR39447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980478" evidence="2">
        <location>
            <begin position="36"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="499" mass="50299" checksum="BF5924810624FE56" modified="2009-10-13" version="1" precursor="true">MKLSHYRSWLSVGAAATIVAAAGAVSMTAAPTAQAAGGCQVDYSVSSQWQGGFGANVSITNLGVPTTGWTLTWTFSAGQTITQLWNGTDTQTGGDVAVTNAPYNGAIPTGGSTSFGFNGSWSTSNPAPVSFALNGTTCIGSGPSGTPTTTPSSPPTTTPSSPPSSTPSSTSSTPSTPPSSSSTRLPCDIYAAGGTPCVAAHSTVRALYSAYGGALYQVRRSSDNATKDISVLTPGGYANAATQDSFCAGTSCVITVVYDQSGHGNSVAYQGPGGAGGSDTPASATRESLTAAGHKVYDLYINPGNSYWHNGASSGMPVGSQPQGAYMVTSGLHVNSGCCFDYGNSETDRRADGAGAMDAINFSTSCWFGGCTGSGPWVQADLEYGLFPGGSSSWNPNQRAFADKYVTAMLKNNGSTQMALKGGSAQTGSLTTLWSGALPRGYNPMKQQGAIILGSGGDCCASNTNLSLGTFYEGAIVAGYPSDATDSAVQASIVAAGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZN0</accession>
    <name>C7PZN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl xylan esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793274.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4684"/>
    <dbReference type="ESTHER" id="catad-c7pzn0">
        <property type="family name" value="Acetyl-esterase_deacetylase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73545">
        <property type="protein sequence ID" value="ACU73545"/>
        <property type="gene ID" value="Caci_4684"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4684"/>
    <dbReference type="eggNOG" id="COG3458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054209_1_0_11"/>
    <dbReference type="OMA" id="VHFAARG"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="34510" checksum="05659AFC5F666F7F" modified="2009-10-13" version="1">MAFVDMTLKKLRDYLPARPEPTDFDAFWAATLAEARTHPLAARFEPVESRLSTVEVEDVTFSGFGGQAVKGWLTRPANAAGPLPTVVEFVGYGGGRGLPHERLVWASAGYAHLTMDTRGQGSAWQVGDTPDDGPSGNSHPGFATRGVLDRDTYYYRRLYTDAVRALEAARTHPSVDPARVLVAGGSQGGGIAIAAAGLVGDLAGVVTDVPFMQHIRHATEITDGYPYKEIAEFCKVHRDKVERVFDTISYVDGVNFAARANAPALYSVALMDDVCPPSTVFASFNHYAGPKEIEVYPYNGHEGGGAHHVARALEFAQSVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZR4</accession>
    <name>C7PZR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4718"/>
    <dbReference type="EnsemblBacteria" id="ACU73579">
        <property type="protein sequence ID" value="ACU73579"/>
        <property type="gene ID" value="Caci_4718"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4718"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_11"/>
    <dbReference type="OMA" id="AKREIYQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="262"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="521"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="564" mass="60990" checksum="E511C6E9242C8A8E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q036</accession>
    <name>C7Q036_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_6683</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795258.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6683"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH6">
        <property type="family name" value="Glycoside Hydrolase Family 6"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75529">
        <property type="protein sequence ID" value="ACU75529"/>
        <property type="gene ID" value="Caci_6683"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6683"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015488_3_1_11"/>
    <dbReference type="OMA" id="ANYNTAV"/>
    <dbReference type="OrthoDB" id="1331351at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="entry name" value="PTHR34876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001100">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="SSF51989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00656">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 9 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005125734" description="Glucanase" evidence="9">
        <location>
            <begin position="46"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="11">
        <location>
            <begin position="41"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="144"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="572"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="162"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001100-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU75529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="633" mass="65333" checksum="43F1C91114177F14" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0B0</accession>
    <name>C7Q0B0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797167.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8627"/>
    <dbReference type="EnsemblBacteria" id="ACU77443">
        <property type="protein sequence ID" value="ACU77443"/>
        <property type="gene ID" value="Caci_8627"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8627"/>
    <dbReference type="eggNOG" id="ENOG50348RI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105289_0_0_11"/>
    <dbReference type="OMA" id="EVECAWY"/>
    <dbReference type="OrthoDB" id="2028156at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27300" checksum="411C8780BF66478B" modified="2009-10-13" version="1" precursor="true">MVTAGVLVALLGICLLIASGTSLALKMGSNRARRLVEGTAIVPIGTLRAGVRRVAVLGTVGFGLGGPVRAPVSEVECAWYRIQLVRSPSRSKDESPPPEDVLFTYAAPGPPALSDSSGAVLVDPAFLISAPNLDDPVATELTYRVLGSDPSGRVESLVPRKFLDDTRRSETLQLWEIRLVAGRQVYVLGSTRQQNGSVMLAPAKHDRFTVFTTDERSTVIARRRTNAANQRELAVFLGRFGAVLTVAGGLILLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0W4</accession>
    <name>C7Q0W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0807"/>
    <dbReference type="EnsemblBacteria" id="ACU69742">
        <property type="protein sequence ID" value="ACU69742"/>
        <property type="gene ID" value="Caci_0807"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0807"/>
    <dbReference type="HOGENOM" id="CLU_1406501_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046187">
        <property type="entry name" value="DUF6215"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19721">
        <property type="entry name" value="DUF6215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="19649" checksum="1B55E0E5FB608C83" modified="2009-10-13" version="1">MDVSHRGTRFQLVAALVVGGLVVAGAVIWNSGGSGGDSDPCRAASQSTADKTGATLCAALKKAGLPALLGVPSAKPVYVGQMAVPGKAATDYPEVHVEWNVGQYSVILSTAQTPVAKPTEQVAGHPAALLSGTSGSQQVNRLEVDWSASGGGGIYAVDVMMVNDSAIAQSDAGRLERMVAAKVLPGLPEWQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1E1</accession>
    <name>C7Q1E1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4809"/>
    <dbReference type="EnsemblBacteria" id="ACU73670">
        <property type="protein sequence ID" value="ACU73670"/>
        <property type="gene ID" value="Caci_4809"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4809"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_5_11"/>
    <dbReference type="OMA" id="LLPMMTF"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="29"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="40910" checksum="F7F8B919E61054B6" modified="2009-10-13" version="1">MSSVSIRSAEDSSASIASSGGGGDGGLGRTLVLALGTFAVGTDAFVLAGFLPDVAASLHTSTASAGQAVTVFAAAYAVASPVVATLTARFPRRLLLVAALIVLAAANAASALAPNLPLLLAARVLAAAGAAGYTPTAGAVTAALVRPEMRGRALAVVVGGLTVATALGVPLGDAAGAVMGWRAALGLVAALCLLTAIAAAVLMPTLPGSAPVPLAARLAALRRPGVASVLPLTVLGMAAAYTVYAYAIPALHALGIADGATAWILAAYGAGAILGNLAAGIAADRLGPTRVLVVGYALMAMTLATFAVLAVAKVHAPALVAVLAITWGASTWCQTPPQQHRLFSAAPSEAPLLMALNASAIYVGIGIGTAAGGLLVASGAAWMFTIAAIVACLALGWLAATATATGHKATRRWSTLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V5</accession>
    <name>C7Q1V5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TPR_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795384.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6815"/>
    <dbReference type="EnsemblBacteria" id="ACU75656">
        <property type="protein sequence ID" value="ACU75656"/>
        <property type="gene ID" value="Caci_6815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6815"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116756_0_0_11"/>
    <dbReference type="OMA" id="YPEERAH"/>
    <dbReference type="OrthoDB" id="1486598at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041656">
        <property type="entry name" value="TPR_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12688">
        <property type="entry name" value="TPR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPR_5" evidence="1">
        <location>
            <begin position="47"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18097" checksum="CD50DAE0B5765BE9" modified="2009-10-13" version="1">MTADLKNDVNRRVAALFAAIDDYDEQKFIAEVDALAAELPEDDADGIFHRGCARDSWGHSDLAVPLYARALEIGGLTGENSRRAVIQMSSSLRNIGRAEDGLATLLKEKDAGGEDHLSDALDCTIALCLSTLGRDREGLSLVLVALAKHLPRYNRSMGNYGRLLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2A2</accession>
    <name>C7Q2A2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797363.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8826"/>
    <dbReference type="EnsemblBacteria" id="ACU77639">
        <property type="protein sequence ID" value="ACU77639"/>
        <property type="gene ID" value="Caci_8826"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8826"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045680_5_1_11"/>
    <dbReference type="OMA" id="RTYGDPF"/>
    <dbReference type="OrthoDB" id="1022681at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05830">
        <property type="entry name" value="Sortase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042003">
        <property type="entry name" value="Sortase_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24842" checksum="2DED0A9AD94073F6" modified="2009-10-13" version="1">MARAGALLRIAIRTVGELLVTSSVLLALFIVYQLYYTNVVGRHVMNQEVNDIHKQWTVAAPARPSAPVVMAAPPPAPMPHNGDDVAILHIPRLGSGLDDAGIPVLEGVGLDILNKATGHYPGTALPGQIGNFSVAGHRKTHGEPFRHLDEMRAGDLVYVETAKDWYTYRIDADPVIVQPTDLGVVDPVPGEPGVRPTQDLMTLTTCNPWWSSTQRMIVTGHLIATRPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3I2</accession>
    <name>C7Q3I2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bac_luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6910"/>
    <dbReference type="EnsemblBacteria" id="ACU75747">
        <property type="protein sequence ID" value="ACU75747"/>
        <property type="gene ID" value="Caci_6910"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6910"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1640738_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="161" mass="18150" checksum="A9364F6D428217F1" modified="2009-10-13" version="1">MTALWYRLVRLSACGRGVFDLSNDNSTVRQVANPWTFSASECCDARPRGPLRYWIWLRSVLTPTGIWCEEAWITTAAQTSTLAFIVALRPDSLAPTLAVQMAATFQRQSGGWLVLNIVTGSDEQEQRRYGRRLGHDRRYERIEAPRVQTMATALTARSGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3P4</accession>
    <name>C7Q3P4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6979"/>
    <dbReference type="EnsemblBacteria" id="ACU75809">
        <property type="protein sequence ID" value="ACU75809"/>
        <property type="gene ID" value="Caci_6979"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6979"/>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_569476_0_0_11"/>
    <dbReference type="OMA" id="HIAFTRY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982497" description="Sialidase domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="148"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="476" mass="48893" checksum="5588CD19D2264BC2" modified="2009-10-13" version="1" precursor="true">MRSNPSRRIGAAAATAALLALPATALGGPAYAAASATPAATSLVQVSSDPYTDSQAQHATEVEPDTFSFGSTVVSAFQVGRVFGGGASNIGWSESTDGGTTWTHGFLPDTTANTGGPYGQVSDASVAYDAKHGQWLISYLGILPSGNVNVAVSRSPDGHTWGNPVTVSSATFDDKNWTVCDNHTASTFYGHCYTEYDDANAGDAEHMRTSTDGGLTWGTQKSPSGNPSGLGGQPVVQPNGTVVVPYSASTSERAFTSTNGGTSWTASVRIATVSHHTVAGLESDSIAPQDELRESPLPSAEIDAAGKVYVTWSDCRFRSGCPSNDIIMSTSTNGTTWSTPTRVPIDATNSTVDHFTPGIGVDPSSSGSTARIGLAYYYYPVANCTDTTCKLDVGYVSSTNGGATWSTPTQLAGPMTLAWLPNTSQGRMFGDYISTSVFAGGNALPVIAVASAPSGSTFTMGMFAPTGGLTIGGAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q454</accession>
    <name>C7Q454_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="12" type="ordered locus">Caci_0983</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0983"/>
    <dbReference type="EnsemblBacteria" id="ACU69914">
        <property type="protein sequence ID" value="ACU69914"/>
        <property type="gene ID" value="Caci_0983"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0983"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_11"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 12" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="10">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="303"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="11">
        <location>
            <begin position="475"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU69914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="629" mass="67696" checksum="DB7A418A4CABB1DE" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Z1</accession>
    <name>C7Q4Z1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793668.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5079"/>
    <dbReference type="EnsemblBacteria" id="ACU73939">
        <property type="protein sequence ID" value="ACU73939"/>
        <property type="gene ID" value="Caci_5079"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5079"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115408_0_0_11"/>
    <dbReference type="OMA" id="LHFCTGP"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="26"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="171" mass="18907" checksum="9EECC1D45A85AA28" modified="2009-10-13" version="1">MPEIEPIGELDARFSERSAKARPWAEVAEVLAAREMFWLSSVRGDGRPHVVPLPAVWLDGALYFCSGSDEQKTKNLLFDPRCVLSAGANALHFGLDVVVEGSAARVTDQDLLQRLVALWKSKLDWDFQAAEDGFRDPHAPNSSVFVFGVKPVKVLAFDKGPYGQTRYSFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q506</accession>
    <name>C7Q506_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate reductase/succinate dehydrogenase flavoprotein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5094"/>
    <dbReference type="EnsemblBacteria" id="ACU73954">
        <property type="protein sequence ID" value="ACU73954"/>
        <property type="gene ID" value="Caci_5094"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5094"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011398_4_2_11"/>
    <dbReference type="OMA" id="WMEGYSD"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="47"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="586" mass="60412" checksum="9260A9BA03B8B463" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q511</accession>
    <name>C7Q511_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5099"/>
    <dbReference type="EnsemblBacteria" id="ACU73959">
        <property type="protein sequence ID" value="ACU73959"/>
        <property type="gene ID" value="Caci_5099"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5099"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_0_11"/>
    <dbReference type="OMA" id="WVSAVWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982892" evidence="1">
        <location>
            <begin position="33"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="47353" checksum="7265FCD653F2C42B" modified="2009-10-13" version="1" precursor="true">MRTNLMRGTAALTLAVTAMAMTACSSSSSSSSAPKGGAASSGSHGKVTLSFVNWDGGMQSAVDQWNKANPDIQVQLTKPSGTGYTLYNKLITNNAAGTNPDVTEVEYQALPALIANKVIVPIDQYVGDISADFDKSSLAQVQFEGKTYGVPQNVCPMVFFYRKDIFDSLGLKAPTTWDEYAADAATIHAKNPKQYIGNFSAVDSGWFAGLAQQAGANWWTTTGTTWNVAIDDAPTQKVANYWSGLIDKGLVSPEPNWSPQWNTDMNNGTIIGWVSAQWAPNQFPSIAKDTAGKWVAAALPAWTAGDSTVGIWGGETEAVTSNSKHPAEAAKFVKWLNASSDGVKTLIQQVDVFPASLANQSQDSLKTPPPFMSDQADYNTLIASAAKNARTFQVWGPNANVTFDAYSNDFAAALQNKTPLTAALTQMQQATVADLKKRGFSVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q530</accession>
    <name>C7Q530_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793707.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5119"/>
    <dbReference type="EnsemblBacteria" id="ACU73978">
        <property type="protein sequence ID" value="ACU73978"/>
        <property type="gene ID" value="Caci_5119"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5119"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_11"/>
    <dbReference type="OMA" id="AWMDRYA"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="20622" checksum="198130635D348CED" modified="2009-10-13" version="1">MPTPPPTPARADAQRNRQRLIEVAQRAFTTGDTKVPLEAVAKEAGVGIGTLYRHFPTRESLVEAVYLAERNRLCAAAEELLANHPPQAALRIWMNHFADYIATKREMADALRALIADGTVTRSQAREQLGTAVRRILDAGAADGTLRPDVDAEDVVVALVGVFSVCTLPDQRDQAGRLLDLLMDGLRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5A8</accession>
    <name>C7Q5A8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CBS domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_7047</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795605.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7047"/>
    <dbReference type="EnsemblBacteria" id="ACU75877">
        <property type="protein sequence ID" value="ACU75877"/>
        <property type="gene ID" value="Caci_7047"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7047"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_2_11"/>
    <dbReference type="OMA" id="TIGRQHP"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="207"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="275"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU75877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="45942" checksum="0E61F04D54614A59" modified="2009-10-13" version="1" precursor="true">MSVLLFWEIVAVVVLVAVAGFSACADAALSRVSRVRAAELVADGVPRAARLKQLVDDPARVLNLVLLLRVACEIAATVLVTVLFMRRIDGAWGAGFAAIGVMIAVSYIFIGVMPRTIGRQHSVRVALHFAGPLALLTTVLGPLAQLLIAVGNAVTPGRGFREGPFASEAELRALVDLAEANSVIEDQERRMVHSVFELGDTLVREVMVPRTDMVFIERHKTLRQALSLALRSGFSRIPVVGENADDVVGIVYLKDLVRRIHEHPSGETTELVESAMRDPVCIPDSKPADELLRDMQAGHIHLAVVIDEYGGTAGLVTIEDILEEIVGEIADEYDVERPSVEHLSPDAARVTARLGVDELGDLFGVDLEDDDVETVGGLMAKRLGRVPIPGAQIEVEGLRLTAESPEGRRRRIGTVLVKRVPQDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5N2</accession>
    <name>C7Q5N2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FBP_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797567.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9030"/>
    <dbReference type="EnsemblBacteria" id="ACU77843">
        <property type="protein sequence ID" value="ACU77843"/>
        <property type="gene ID" value="Caci_9030"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9030"/>
    <dbReference type="eggNOG" id="ENOG5031HHY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116295_0_0_11"/>
    <dbReference type="OMA" id="LCITAHA"/>
    <dbReference type="OrthoDB" id="1684141at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032330">
        <property type="entry name" value="EF-G-binding_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16571">
        <property type="entry name" value="FBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBP_C" evidence="1">
        <location>
            <begin position="9"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="17725" checksum="CBCB7C234E57D37A" modified="2009-10-13" version="1">MHPLTEDAIRASFANCSQGEAKRIPMPRDLAQTPWDDLDFLGWRDLGAQDRAYLVTPRGDGLTGVTLRSAASRKGFLRRNLCSLCLTTHAGGGVSLMTGRKAGDAGRQGNSVGLYLCSDLACSLYIRGVKSPGAAGDRLEETLKVEEQVGRMAGKLEEFLARLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q675</accession>
    <name>C7Q675_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787374.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3173"/>
    <dbReference type="EnsemblBacteria" id="ACU72081">
        <property type="protein sequence ID" value="ACU72081"/>
        <property type="gene ID" value="Caci_3173"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3173"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141550_0_0_11"/>
    <dbReference type="OMA" id="GPVPYWH"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11328" checksum="F9D95D26BAD644C4" modified="2009-10-13" version="1">MTTAIRSQVIPVSDLDAAKAVYTALYGDPHTDTPYYVGYDAGGFEVSLTPGDVSGGPVAYTDVEDLDGAREKLLAAGATERDAPRQVAPGARVCVLLDKDGNAIGLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X4</accession>
    <name>C7Q6X4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795715.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7158"/>
    <dbReference type="EnsemblBacteria" id="ACU75987">
        <property type="protein sequence ID" value="ACU75987"/>
        <property type="gene ID" value="Caci_7158"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7158"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="NHLRVIC"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27131" checksum="C954536181BC5E92" modified="2009-10-13" version="1" precursor="true">MGGGILVEGLTKRYQAVTAVDDLTFEVEAGKVTAFLGPNGAGKTTTLRMILGLVRPDAGRALIDGFPYARLPHPRRAVGAVLETGGFHPGRSGRDHLRVLAMAERIPATRVDDVLVRVGLADAADRRVKGYSLGMRQRLGLASALLGDPAVLILDEPANGLDPAGMAELRELLRDLAAEGRTVVMSSHVLSEVAQTVDHVVIAAEGRLRYAGRLADLTAPQGETLEAAFLRLTASAATTAHDGTAADAPVAEVRSLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Z2</accession>
    <name>C7Q6Z2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7176"/>
    <dbReference type="EnsemblBacteria" id="ACU76005">
        <property type="protein sequence ID" value="ACU76005"/>
        <property type="gene ID" value="Caci_7176"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7176"/>
    <dbReference type="HOGENOM" id="CLU_2068877_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="13425" checksum="AE929F4D281BB197" modified="2009-10-13" version="1">MSVGWETTTLLRVADQAHVRSEPSGDGRETQGLIECPSCHRVTDWLIAAMGMRVDVACRCGNRWEIPTTLQHVVAMAESQPIDPQWTCLDDARRALGFTRHADTTRGRRRRRHRRSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E4</accession>
    <name>C7Q7E4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Penicillin-binding protein transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785526.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1307"/>
    <dbReference type="EnsemblBacteria" id="ACU70232">
        <property type="protein sequence ID" value="ACU70232"/>
        <property type="gene ID" value="Caci_1307"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1307"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025328_0_0_11"/>
    <dbReference type="OMA" id="CNTAFIK"/>
    <dbReference type="OrthoDB" id="423699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982607" evidence="2">
        <location>
            <begin position="28"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="289"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="573" mass="57491" checksum="B4D11E58385D51D7" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I1</accession>
    <name>C7Q7I1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3267"/>
    <dbReference type="EnsemblBacteria" id="ACU72174">
        <property type="protein sequence ID" value="ACU72174"/>
        <property type="gene ID" value="Caci_3267"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3267"/>
    <dbReference type="eggNOG" id="COG2091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057011_2_1_11"/>
    <dbReference type="OMA" id="DTIFEQH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="27555" checksum="7FAA25629FA1470B" modified="2009-10-13" version="1">MTVVGGERVVAGGDGGSGLVPVSIPVPAPGSAPVAVSVSGSGSVAASDSASVSVSAWLVGDVPSAAVADLLATLDDEECRRLARLPSAEGRRRFVIAHGAMRRVVGECLGAPPAELRWETGEQGKPELVGEWTGIHANLSHSGDRCLIAVSRERAVGADIQRVVPGLEVVAMARRYFPEAEAQDVIDAADPADVFGRLWARKEAVTKAAGGRLTQVLPLATPPDAIVEVAGYRYRVADVEAPAGFHAAVALAGAEQFMVEVNEWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q805</accession>
    <name>C7Q805_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5313"/>
    <dbReference type="EnsemblBacteria" id="ACU74172">
        <property type="protein sequence ID" value="ACU74172"/>
        <property type="gene ID" value="Caci_5313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5313"/>
    <dbReference type="HOGENOM" id="CLU_3041635_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983004" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="5685" checksum="F6B2DE310C881DC6" modified="2009-10-13" version="1">MEFITRLRRALRAAKAPLYTDLGSTVAQAASTVSIATGISGGAPLPTEKKQPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q828</accession>
    <name>C7Q828_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5336"/>
    <dbReference type="EnsemblBacteria" id="ACU74195">
        <property type="protein sequence ID" value="ACU74195"/>
        <property type="gene ID" value="Caci_5336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5336"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="PGVIEHR"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="392" mass="40219" checksum="7B191D22FCB535C6" modified="2009-10-13" version="1">MNSAARRRMASLSELAGLVADGAATTRSAIVGATGLSRAAIAQRVDLLIERGLLVETEPAATDRGRPPLALDLSDARIVVAGCDLGATHSRLAVATLSGRVLAERERAIDINAGPDAVLAGVRTDLEELLAAAGRPADHLRAVGIGVPGPVEFASGTVVRPPIMAGWDGCRIPAYFEGRYAAPVLVDNDVNAMALGEYTHRQASRHLLYVKVGTGIGCGIVSDGVLHRGASGAAGDIGHIQLPGHEDVLCHCGNTGCVEAVASGAAIAAALRAQGADAARAADVVRLVSAGHAAARRHVRLAGQRIGEVLASLVSFHNPDTIVIGGILAKLHEDLLADVRAVIYRRALPLATRSLAIETSVLGERAGMLGAVRLAARHLLSAEGMAGIIGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8F8</accession>
    <name>C7Q8F8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76146">
        <property type="protein sequence ID" value="ACU76146"/>
        <property type="gene ID" value="Caci_7317"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7317"/>
    <dbReference type="eggNOG" id="ENOG502ZPP7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_432581_0_0_11"/>
    <dbReference type="OMA" id="GQYVANH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="632" mass="69863" checksum="867F45F01161CAF6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Q0</accession>
    <name>C7Q8Q0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1392"/>
    <dbReference type="EnsemblBacteria" id="ACU70315">
        <property type="protein sequence ID" value="ACU70315"/>
        <property type="gene ID" value="Caci_1392"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1392"/>
    <dbReference type="eggNOG" id="COG3550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070584_0_0_11"/>
    <dbReference type="OMA" id="IHRADAF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010872">
        <property type="entry name" value="MDMPI_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07398">
        <property type="entry name" value="MDMPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="MDMPI_C" evidence="1">
        <location>
            <begin position="159"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29780" checksum="D138D677C9B6CEA1" modified="2009-10-13" version="1">MEGKPMMSETANPHLVHTDRFTAEAERVATLLDGLGTDDWTRPVPTCPGWTVRKVARHIGTAHRWAAAIVRSPGSEAVNPRSLDLGFPESNAGYSDWIRAGAAELAHAVREAGPDKPVWSWGPDQHARFWARRMLHETTMHGADMIMALGRTPEFDPAVAADGIDEFLTVLPSAAAFSPKIRALTGDGETLHLHATDADPASAAGERAEWLITLEPNGFRWRRAHAKGAAAVRGPVGELYLFLWRRRSPGAQEIEVLGDHVLVDHWVTNATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R9</accession>
    <name>C7Q8R9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1411"/>
    <dbReference type="EnsemblBacteria" id="ACU70334">
        <property type="protein sequence ID" value="ACU70334"/>
        <property type="gene ID" value="Caci_1411"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1411"/>
    <dbReference type="eggNOG" id="ENOG5032T2E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440288_0_0_11"/>
    <dbReference type="OMA" id="TRWVEDE"/>
    <dbReference type="OrthoDB" id="1681567at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21906" checksum="7D5096F69013DEAF" modified="2009-10-13" version="1">MTKRLTAEVEEKIVRCLFLEADALRWAHLPLGKKTEMYEKWATDPEIGGKLKDFMTLEQVRVWIKDGVMKEYARALYGEGKYAPLVPNPAASLDQLVNSALGSGWNALPGTRRIKPMRVRALKGEQTVTLTWADSAANFKHLVWAALSAIADGDQTDWVLCVVDSFESPTPDDIKKHHKRIAERCRLRVVHINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X4</accession>
    <name>C7Q8X4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787587.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3388"/>
    <dbReference type="EnsemblBacteria" id="ACU72294">
        <property type="protein sequence ID" value="ACU72294"/>
        <property type="gene ID" value="Caci_3388"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3388"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088151_0_0_11"/>
    <dbReference type="OMA" id="TYETHER"/>
    <dbReference type="OrthoDB" id="1550827at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="2">
        <location>
            <begin position="56"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27100" checksum="D62AFF1CD1900992" modified="2009-10-13" version="1">MIQDHVDGVAPSASAGATAPYTVTAEFYDILQAESDRRLAEHRFAAAASAARVGIVDVGAGTGIVTEVLLARSAAPVHAVEPATPMRVALLTRLAALSADVRARVTVHPGTLQGAGLTRQADLVVCANVAGVVEPPLRRLLWRAAAEALVPGGQLLVDPPPTSVPDEPTRRDLPPVRVGPDTYSAQVCLRPDRGLLAVAYTYRVERGGRTVRLEHEEFTMWPASTDTVHEELREAGFSVTGPANGLVRATRDPDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Y9</accession>
    <name>C7Q8Y9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3403</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787602.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3403"/>
    <dbReference type="EnsemblBacteria" id="ACU72309">
        <property type="protein sequence ID" value="ACU72309"/>
        <property type="gene ID" value="Caci_3403"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3403"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_3_1_11"/>
    <dbReference type="OMA" id="HAPGFSF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980703" evidence="3">
        <location>
            <begin position="32"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="4">
        <location>
            <begin position="101"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27104" checksum="04E144D3DC205BBB" modified="2009-10-13" version="1" precursor="true">MTARASVRRRVHERLGARLGLTLFVAVPAAAAAGLIAVAVESAWDPFRRLDQHTASYLHDHTMGHPDVIKTLLRVSDIGGPTPSRVLVGVVAVALWLRGARRLAVWAASTMVAGAVLDIGLKTLVDRTRPHLPNPFAHAPGASFPSGHAMTSALACGIVLLLVLPLVGRAGTIAAWTIAVLIVVAVGYSRVALGVHWVTDVVGAWLLAIALLAASVSAFQTWRVEHGLRRARPTTEGVEPEEPEEILSAEHRGSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z0</accession>
    <name>C7Q8Z0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3404"/>
    <dbReference type="EnsemblBacteria" id="ACU72310">
        <property type="protein sequence ID" value="ACU72310"/>
        <property type="gene ID" value="Caci_3404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3404"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_3_2_11"/>
    <dbReference type="OMA" id="RTRQWWY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="108"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="24413" checksum="D4B8EAC9317F95E8" modified="2009-10-13" version="1">MTVSATQVARRPHHDARATAIALILGAATILAVLIALGWLVTKPLAHHWPLSAEDGVNRYFAQHRDHALNGVSGFFSTIANTTSAIALSALAFIVIRLLTHRWTESLFVATALVAEVSVFLVTTMVVDRARPMVPHLDTAPPTSSFPSGHTAAATALYVAVALVARRHGAAWPVWLLVAVPCAVALSRLYRGMHHPSDVLAGALLGGLCVLLADRVVLTDRLRRPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q936</accession>
    <name>C7Q936_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3450"/>
    <dbReference type="EnsemblBacteria" id="ACU72356">
        <property type="protein sequence ID" value="ACU72356"/>
        <property type="gene ID" value="Caci_3450"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3450"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_16_0_11"/>
    <dbReference type="OMA" id="QYAVMWY"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="43"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="499" mass="52797" checksum="00FDC780EBB250E8" modified="2009-10-13" version="1">MSPEDRTRPRFTGHDAKRPGSYLFGDDGKGWSAVKVYASGFRTFLILWSGQLLSLVGSALSGFALGVYVYQLTGSVTKIGLVYALSFLPLIAVSPMAGALVDRRGPRRALLESNIGCMLIMLVLAILLATHTFRWWHVYFVVSLTSVLTAMQMPAFEASVPALVAKKDLGRANGMRMFASAASGVLGPVVAGALLLAIKVQGVVLMDCLSFGFAIATLLVVRIPGARRDDQAAETSEPSTLTGDFKEGWRYVAARRGLLAMMGYLGAISFFIGVADVVITPLVLDFASARGLGAVMSIGAAGMLLTSLVMSVWGGPKRRVRGMYLFSLVMGGAIVLGSLRPNVALVALAAFLFLGAAPLIIAPSQSIVQTKVEPQLLGRVSALKNMITFTPQLVAYVLAGPLADDIFEPWVGRRHVGSSTFRTLVGDGTGRGIAFLLMVMGVLLAVTVGLAALYRPLRHVEEELPDVMSEAPEEMADGVADDDGVAGDEVTDPAAASTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q971</accession>
    <name>C7Q971_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_3485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3485"/>
    <dbReference type="EnsemblBacteria" id="ACU72391">
        <property type="protein sequence ID" value="ACU72391"/>
        <property type="gene ID" value="Caci_3485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3485"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_71_11"/>
    <dbReference type="OMA" id="TTFRWTL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007891">
        <property type="entry name" value="CHASE3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05227">
        <property type="entry name" value="CHASE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982640" description="Histidine kinase" evidence="8">
        <location>
            <begin position="39"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
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        <location>
            <begin position="208"/>
            <end position="260"/>
        </location>
    </feature>
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        <location>
            <begin position="289"/>
            <end position="537"/>
        </location>
    </feature>
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        <location>
            <begin position="423"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU72391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="565" mass="60669" checksum="858AE457EB1F1B7A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9D9</accession>
    <name>C7Q9D9_CATAD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5426</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5426"/>
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        <property type="gene ID" value="Caci_5426"/>
    </dbReference>
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    <dbReference type="OMA" id="LWQRYTG"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="16632" checksum="CB33A05F38F89EEC" modified="2009-10-13" version="1">MNILQIVLIIAVAALVIGKRLTGRPVDTRRSVVMPGILAVYGWFILQKSGTLTHTDQVWLAVEGAVSVAIGLVRGSTIRLYERDGVLWARYRPLTLLLWIGSIAARFGLEAAAVGAGAGKAAMTSSTMLMFGVSLAAESLIVLPRAYASGIPVLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9M0</accession>
    <name>C7Q9M0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7362</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7362"/>
    <dbReference type="EnsemblBacteria" id="ACU76189">
        <property type="protein sequence ID" value="ACU76189"/>
        <property type="gene ID" value="Caci_7362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7362"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="RGMRKYD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="29"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="624" mass="66477" checksum="19BB2C05072D440B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y8</accession>
    <name>C7Q9Y8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron-sulfur cluster binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785680.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1463"/>
    <dbReference type="EnsemblBacteria" id="ACU70386">
        <property type="protein sequence ID" value="ACU70386"/>
        <property type="gene ID" value="Caci_1463"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1463"/>
    <dbReference type="eggNOG" id="COG1139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027059_1_0_11"/>
    <dbReference type="OMA" id="HCPVYDK"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019516">
        <property type="term" value="P:lactate oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004452">
        <property type="entry name" value="4Fe-4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024569">
        <property type="entry name" value="4Fe-4S-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47153">
        <property type="entry name" value="PTHR47153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11870">
        <property type="entry name" value="DUF3390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00273">
        <property type="entry name" value="TIGR00273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="LUD_dom" evidence="4">
        <location>
            <begin position="78"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="321"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3390" evidence="5">
        <location>
            <begin position="403"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="485" mass="52833" checksum="1E390A3D9356560A" modified="2009-10-13" version="1">MSGDQVNVVWLGSPTFPQAAHDALQDTQLRRNLKHATTTIRDKRLRAVAELDDWETLREAGSQIKDRVMRHLDEYLLQLEASVTAAGGVVHWAEDAREANRIVSELVRAKGATEVVKIKSMATQEIGLNEALEDDGIEATETDLAELIVQLNDDRPSHILVPAIHRNRSEIRDIFQREMGKHGIAAPDDLTDEPRVLAEAARVHLREKFLRAKVAISGANFACADTGTVGVVESEGNGRMCLTLPETLITVMGIEKVLPSFSDLEVFLQLLPRSSTAERMNPYTSLWTGVTPGDGPQEFHLVLLDNGRTKTLADTAGRSALHCIRCSACLNVCPVYERTGGRSYGSVYPGPIGAVLTPQLVGVGTSEHADSLPFASTLCGACYDACPVRIDIPEMLVHLRAKVVDAHRGGVPKPEALAMKGARVVFGSPRRLAWAERLGAIGGRVAGIGGGRWLPGPARKWTGARDVPVPARESFRAWWRKAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y9</accession>
    <name>C7Q9Y9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785681.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1464"/>
    <dbReference type="EnsemblBacteria" id="ACU70387">
        <property type="protein sequence ID" value="ACU70387"/>
        <property type="gene ID" value="Caci_1464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1464"/>
    <dbReference type="eggNOG" id="COG1556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090664_0_0_11"/>
    <dbReference type="OMA" id="VPDHHIC"/>
    <dbReference type="OrthoDB" id="1580190at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="114"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="22573" checksum="001E1159C3BC349F" modified="2009-10-13" version="1">MSEAKGRILERVRSGLRDVPRDERAEDVEVTRAYVDSHAPGDPGAVVELFAERVADYRATVVRVAESGAPEEIARILTEHAVANLVVPPGFPDALVARYEGSRLSDEPPLTPAELDASDGVITLAAQGIAVTGTIVLDAGPGQGRRALSLVPDLHLCVVRAAQVAADVPIAIRSLVPTRPTTFISGPSATSDIELDRVEGVHGPRTLVVVLISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA05</accession>
    <name>C7QA05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)</text>
            <dbReference type="Rhea" id="RHEA:39663"/>
            <dbReference type="Rhea" id="RHEA-COMP:12939"/>
            <dbReference type="Rhea" id="RHEA-COMP:14378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:133980"/>
            <dbReference type="ChEBI" id="CHEBI:139511"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the F420H(2)-dependent quinone reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785697.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1480"/>
    <dbReference type="EnsemblBacteria" id="ACU70403">
        <property type="protein sequence ID" value="ACU70403"/>
        <property type="gene ID" value="Caci_1480"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1480"/>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114921_0_1_11"/>
    <dbReference type="OMA" id="GQEKHPA"/>
    <dbReference type="OrthoDB" id="581851at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004378">
        <property type="entry name" value="F420H2_quin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04075">
        <property type="entry name" value="F420H2_quin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00026">
        <property type="entry name" value="hi_GC_TIGR00026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="17796" checksum="E0CEB6129026A779" modified="2009-10-13" version="1">MTPKALKSTAQALARQRWFVAVGKRTLPHVDRVLYKATRGRVGAMSPSGLTGLLLTTVGRKTGKERSVPLLYVGHEGKYYLTGSNWGQEHHPVWTLNLMANPEATLTVKGKKIPVTARLLEGEERTQIWPVLTTTWPNFDVYTERSGRELRVFELTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA40</accession>
    <name>C7QA40_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1517</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1517"/>
    <dbReference type="MEROPS" id="S26.025"/>
    <dbReference type="EnsemblBacteria" id="ACU70438">
        <property type="protein sequence ID" value="ACU70438"/>
        <property type="gene ID" value="Caci_1517"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1517"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_0_0_11"/>
    <dbReference type="OMA" id="RSQVWVK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="32749" checksum="DEBE906F1794D935" modified="2009-10-13" version="1" precursor="true">MRPVAKGQRRRLKPVRLWKELPILFGVALLLALVIKTFFVQAYFIPSESMQHTIEPGDRVLVNKLTPWFGWTPQRGQIVVFKDPGGWLDPSEIKKDNAVVGGVKKVFSWVGLLPEGNEQDLIKRVVGVPGDVVQCKGVGQPVTVNGIPLDEHSYLFRGPDGQLDDPSQTPFGPITVKPHTVFVLGDHRSDSGDSRVHLQETSQGLVPYSDMQGHAFVRIWPLTRISGLGTPSTFSLKNSAQAVQGAAGVPTLLWGFTLAVPLRARQMRRRRRGGAVLPDPAGVTNRLRGRLGTERPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA62</accession>
    <name>C7QA62_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC transporter transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785754.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1539"/>
    <dbReference type="EnsemblBacteria" id="ACU70460">
        <property type="protein sequence ID" value="ACU70460"/>
        <property type="gene ID" value="Caci_1539"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1539"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051674_1_1_11"/>
    <dbReference type="OMA" id="ACWATAN"/>
    <dbReference type="OrthoDB" id="1828250at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="29354" checksum="D51D60B57560BDBA" modified="2009-10-13" version="1">MTAAPATAAHPGPGPAIDGRAGFGNVISSEWLKIRTVRSTFWTLVTLFAGSAVITLLICLAAADSYAKDLAAGKPDSADIVLVGLAFVGQIAAYVLGVMTISAEYSTGGIRTTLTAMPRRTEILVAKAILLAVMVFVIGLATAFLCFYLGNIPLRAKHVNVNLSYPGATRAIFGSALYLAGLSLFGLAMGFLLRHTAGAITIGLALIFIIGNLVQLIPGSVGRWLFKVMPGNAGGQVTAFGETDRHADKAFAPWTGFTVFLIEVVVLLIVGALLFERRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA78</accession>
    <name>C7QA78_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative pim oncogene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785770.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70476">
        <property type="protein sequence ID" value="ACU70476"/>
        <property type="gene ID" value="Caci_1555"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1555"/>
    <dbReference type="HOGENOM" id="CLU_1802604_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="13977" checksum="DD29A7E1DED5FF39" modified="2009-10-13" version="1">MNTDADRSDGVIHSDPDFGGGAVAQPDSEAHSAGVIQRDPDWAGGAVGQSEAVVQPDPDWTGGAVAQPDAVVQPDPGATTGGGVAQPDAAERPDPDVTGGAVKQPDPQWGGGAVKQPDPEMTGGGVAQPDAAGRPDPGEAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG0</accession>
    <name>C7QAG0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792188.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3554"/>
    <dbReference type="EnsemblBacteria" id="ACU72459">
        <property type="protein sequence ID" value="ACU72459"/>
        <property type="gene ID" value="Caci_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3554"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_1_1_11"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="20484" checksum="56703C1D95C0B531" modified="2009-10-13" version="1">MSIDPPAGSDPTTAAGPDFAGGAVPAGEARIRDLMAATVELALSSVALTSMGASLIGMHPTDMFCLWHVTESAASEPVTSGKLGELTGLTSGAITGVIDRLEAAGFLRRERDTQDRRKLFLVPVPEKVGQIYELYAPLHETFRAAEARYDEKQQELILAFLRTTTELMRHNVNTMRQARKEERRNGTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAR6</accession>
    <name>C7QAR6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5530"/>
    <dbReference type="EnsemblBacteria" id="ACU74389">
        <property type="protein sequence ID" value="ACU74389"/>
        <property type="gene ID" value="Caci_5530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5530"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_4_11"/>
    <dbReference type="OMA" id="QRAYPVR"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="40"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33610" checksum="1FFBE68229C31FA0" modified="2009-10-13" version="1">MAEREYVYPPVIRAMMGAFRALDLKVDVRGADRIPRSGGAVLASNHISYLDFIFAGAAALPSRRRVRFMAKKEVFDNRISGPLMRGMRHIPVDREAGLSSYRQALANLKSGEVVGVFGEATISRSFMIKDLKNGAVRMAQAADVPLIPVVLWGTQRMWTKGRPKNLLQRHVPITVLVGEPMYPKKGQNSNDLTAELHARLSALLDEAQSTYPDKPSGPADSWWLPAHLGGTAPTLEEAAEMDARDREEKDGAKDSAKDGAKDGDAKPEQAAAPAPATETVAAKDAGADANADAPEEAVVAAETTPAEDTADDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB10</accession>
    <name>C7QB10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitinase</fullName>
            <ecNumber evidence="5">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5624</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5624"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74483">
        <property type="protein sequence ID" value="ACU74483"/>
        <property type="gene ID" value="Caci_5624"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5624"/>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_0_1_11"/>
    <dbReference type="OMA" id="HNEIGAA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981518" evidence="3">
        <location>
            <begin position="29"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="4">
        <location>
            <begin position="45"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="421" mass="43331" checksum="9871BB75FFFACEE1" modified="2009-10-13" version="1" precursor="true">MATASLKRRLALPTAALALAAGTTMALAATGHAAPGTAALSSTWYASAPYLMPEDNSPPDISAVMDATGQKAFQLAFILAPNGGGCSATWGGTSPIGSDTTIPAVISTIRGKGGDVSVSVGGYGGTKLGQTCGSVAATAAAYQQVISTYSLHAIDFDLEEPEYENTAAIANELGAAQTLQRNNPGLYVSVTMPGTSAGTGWFGTQLLDQAHSIGFAPNNFSIMPFDGGFSGAASQVSALEAFHGLLESHMGWDSTTAYQHEGVSMMNGRTDAAEFFYQSDFQTVLNYATSHGLARYTYWSVNRDRQCSPPDNNGTLSGSCSSVPQNNWDFTKFTAQFAGAATPPPPPPTSSTPTTTPPSSPTSSTTGGGGGTCTAAAWNSSTAYTGGQKVSYNGHQWTAKWWTEADIPGGSAGVWTDNGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB22</accession>
    <name>C7QB22_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796038.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7488"/>
    <dbReference type="EnsemblBacteria" id="ACU76313">
        <property type="protein sequence ID" value="ACU76313"/>
        <property type="gene ID" value="Caci_7488"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7488"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_2_1_11"/>
    <dbReference type="OMA" id="CEYEWGV"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="59"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="20739" checksum="95D5FDA653483ABE" modified="2009-10-13" version="1">MAARIPPLSPPYSAEAADLLDRMMPGDQEPIALFRTFARNLPMAEALHVWGSHVLSRRLTLTLRDREILIDRTCARCGCEYEWGVHIAHFADRAALTGDQITALTHGTSADPCWTTDRDRLLLDAADALHDENDIDDALWTRLAAEFTDDQLLDLLLVCGWYHAISFTARAARLPLEPGAARFETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBC3</accession>
    <name>C7QBC3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpf</name>
        <name evidence="5" type="ordered locus">Caci_7590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796139.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7590"/>
    <dbReference type="EnsemblBacteria" id="ACU76414">
        <property type="protein sequence ID" value="ACU76414"/>
        <property type="gene ID" value="Caci_7590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7590"/>
    <dbReference type="eggNOG" id="COG1544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071472_0_0_11"/>
    <dbReference type="OMA" id="HGGYGVI"/>
    <dbReference type="OrthoDB" id="1766263at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00839">
        <property type="entry name" value="HPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034694">
        <property type="entry name" value="HPF_long/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1 2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="4">
        <location>
            <begin position="155"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="237" mass="26213" checksum="08893BA0E65DB4CA" modified="2009-10-13" version="1">MDIVVKSRHHEVTDRFRRHVVEKLAKVEEMDGKAISLTVVLGEEKNPRQSEQKDRIELTLDCPRSPVIRAEACAGDPYSALDLAAAKLQAQLRRVKDRRKIHRNRKAIADSIKHLPPMADLPPGTAPLLTSDGAAGDNPEVDLPAYGVPGQAGEGPMVVREKTHAAAPMTLDQALYEMELVGHDFYLYVDKDSGLPAVVYRRRAYDYGVIHLEAAEEMAEPMINGSSPSDRMASARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBU6</accession>
    <name>C7QBU6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792294.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3663"/>
    <dbReference type="EnsemblBacteria" id="ACU72565">
        <property type="protein sequence ID" value="ACU72565"/>
        <property type="gene ID" value="Caci_3663"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3663"/>
    <dbReference type="eggNOG" id="ENOG5034B15">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_770953_0_0_11"/>
    <dbReference type="OMA" id="CERAVRW"/>
    <dbReference type="OrthoDB" id="2137112at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37954" checksum="F6E7D2103DF884B4" modified="2009-10-13" version="1">MANHDDVRIDLAGILRQLEDNGYDDVRVEFAPVGTAGPAVSDAVSRGVVAANEAAADRVWGAAPTATLAGVSVKLMDPYDLDAVSEWLAAFAEVLRAGGLSGDLRATPLVGLPEWISQIADPMVTAYVALAAPAPGRSTDQWCERAVRWASEAGGDAYLSSAGMNQVDTSGEVAAHLSSVLLASSSAAVRYADEGASRAAFVHMNPNGQAVYQVYDPAASPAAQVDRARAAILAEAAQASFAFVAPTPYQVYSWDDRGRALQPLQPLWPEIGAAVLRVHANLWSRLVPDAHCIQLLTQEHMSLVSDLSQWSVTEVTPGRFLVEASDLAEWLRPGGPANSTVDKARADFGRALASPDDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBU7</accession>
    <name>C7QBU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792295.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3664"/>
    <dbReference type="EnsemblBacteria" id="ACU72566">
        <property type="protein sequence ID" value="ACU72566"/>
        <property type="gene ID" value="Caci_3664"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3664"/>
    <dbReference type="eggNOG" id="ENOG5032T9G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087620_2_0_11"/>
    <dbReference type="OMA" id="TAMIISP"/>
    <dbReference type="OrthoDB" id="2003359at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046291">
        <property type="entry name" value="DUF6328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19853">
        <property type="entry name" value="DUF6328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17626" checksum="418A46512582DAEC" modified="2009-10-13" version="1">MAVDKRDTGSPSRHETADERADRNLVELLQELRVLQTGVQIIFAFLLSVAFTARFTQLSATQQYVYIAALLMSVISVAVLATPVAIHRGLFRSGMKEQVVILSTHCARLGMLLLSIALDCAVFLIIDVVIGRIAASVITAVVAVAFLALWFVFPWALRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY9</accession>
    <name>C7QBY9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792337.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3706"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH87">
        <property type="family name" value="Glycoside Hydrolase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72608">
        <property type="protein sequence ID" value="ACU72608"/>
        <property type="gene ID" value="Caci_3706"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3706"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009451_0_0_11"/>
    <dbReference type="OrthoDB" id="32528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="Pectate_lyase_SF_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pectate_lyase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982996" evidence="2">
        <location>
            <begin position="26"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="675"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="823" mass="83837" checksum="979565D9D78994BE" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC28</accession>
    <name>C7QC28_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3745"/>
    <dbReference type="EnsemblBacteria" id="ACU72647">
        <property type="protein sequence ID" value="ACU72647"/>
        <property type="gene ID" value="Caci_3745"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3745"/>
    <dbReference type="eggNOG" id="COG1100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_665507_0_0_11"/>
    <dbReference type="OMA" id="IVAFMEG"/>
    <dbReference type="OrthoDB" id="1616473at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="45374" checksum="231090DC4AD76CFA" modified="2009-10-13" version="1">MTGVDTYHVVALGSPGSGKTVYLSALHHVLGNDPDAVGRGITATVEEPDKRALLAKTYDLAVEPEDPSWPAGTHSGEQMREFVFAMKVSWTQKSMRGTLKRRTFHPLNVSYVDYAGEWIPEAYEQSAEVLEPFKKRVREAHALLGIIDGLRLLQFMQGHRSTSFMNDQVRPIVAFMEGTDVPLHFIITKWDLLDSRGITLDAVRTKMLESGGAGFGKLVESRTAQAVFTRRPQGSIRFIPVTSLGGLAVLQDDWTITKNAAARASQQYVEVPLLATVYDICDLAARRLRAGQAGDAAGSEAADAAGVDVQRVGQFAQRQLDGQHGLNAKIGLTGISISLSQIVAFMADNGQGAVRLLGKPAMKTGRTMRRGVRRVKARDLKGVRSPEAALYYVMRTLRHKLQAFEAEQPSSMLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC63</accession>
    <name>C7QC63_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="20" type="ordered locus">Caci_5652</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794240.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5652"/>
    <dbReference type="EnsemblBacteria" id="ACU74511">
        <property type="protein sequence ID" value="ACU74511"/>
        <property type="gene ID" value="Caci_5652"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5652"/>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_11"/>
    <dbReference type="OMA" id="EYVDRMV"/>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="35"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="443"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="17">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="621"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="656"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU74511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="703" mass="79011" checksum="1481F120BAD56211" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC83</accession>
    <name>C7QC83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794260.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5672"/>
    <dbReference type="EnsemblBacteria" id="ACU74531">
        <property type="protein sequence ID" value="ACU74531"/>
        <property type="gene ID" value="Caci_5672"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5672"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015805_4_1_11"/>
    <dbReference type="OMA" id="WQQFART"/>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="125"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="211"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="296"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="54377" checksum="4E6CD61258FD3BC0" modified="2009-10-13" version="1">MTSSTETARTPQVAINDIGSAEEFLAAIDLTIKYFNDGDIVEGVIVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPNEVVAVGDHIEALVLQKEDKEGRLILSKKRAQYERAWGTIEEIKEKDGIVTGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYVGKELEAKIIELDKNRNNVVLSRRAWLEQTQSEVRQNFLTTLQKGQVRSGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVEVGQEVTVEVLDVDMDRERVSLSLKATMEDPWQTFARTHAIGQVVPGKVTKLVPFGAFVRVDEGIEGLVHISELAERHVEVPEQVVNVGDEIFVKVIDIDLDRRRISLSLKQANEGLTGDIETDQFDPALYGMAATYDDQGNYIYPEGFDPETGEWLEGYDAQREVWEGQYAEAHTRYESHQKQIAEARKADAEAGVQENAEGAPSSYSSGVVEETTGGALASDEALAALREKLSGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA0</accession>
    <name>C7QCA0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenide, water dikinase</fullName>
            <ecNumber evidence="5">2.7.9.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenium donor protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selD</name>
        <name evidence="8" type="ordered locus">Caci_5690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Synthesizes selenophosphate from selenide and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + hydrogenselenide = AMP + 2 H(+) + phosphate + selenophosphate</text>
            <dbReference type="Rhea" id="RHEA:18737"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:29317"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the selenophosphate synthase 1 family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5690"/>
    <dbReference type="EnsemblBacteria" id="ACU74548">
        <property type="protein sequence ID" value="ACU74548"/>
        <property type="gene ID" value="Caci_5690"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5690"/>
    <dbReference type="eggNOG" id="COG0709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032859_0_1_11"/>
    <dbReference type="OMA" id="RWNKINM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00625">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SelD_I"/>
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        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
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    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="62"/>
            <end position="169"/>
        </location>
    </feature>
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            <begin position="181"/>
            <end position="326"/>
        </location>
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        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <begin position="60"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="63"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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            <position position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
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            <end position="153"/>
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        <ligand>
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            <note>ligand shared between dimeric partners</note>
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    <feature type="binding site" evidence="5">
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            <position position="236"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
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    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008026"/>
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    </evidence>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU74548.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="35520" checksum="5C478E8B4867DF2F" modified="2009-10-13" version="1">MLEEITYSESDEVAGVRLTQFARGGGCACKIPAGELESILGAVGATAFTGDHELIVGLDHGDDAAVVRLAGDTALVVTTDFFTPVVDDAYDWGRIAAANALSDVYAMGGTPVVAVNILSWPRDLLPMELVAEVLRGGFDVTRAAACHLAGGHSVDDAEPKYGLAVTGVVQADRLLRNDAGRPGTPLSLTKPLGIGVLNTRHKATGERFPQAVATMTELNRDASQAALAAGARCATDVTGFGFLGHLYKLARASGVTAVVDPAAVPYLDGAREAARDGYVSGGTRRNLDWVSPNVEWGSGVDELERLLLADAQTSGGLLVAGLVPGAPVVGELVEQREHAVVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCC7</accession>
    <name>C7QCC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
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    <gene>
        <name evidence="11" type="ordered locus">Caci_5717</name>
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    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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            <taxon>Bacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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            <end position="75"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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            <end position="344"/>
        </location>
    </feature>
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            <end position="613"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="419"/>
        </location>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="620" mass="66334" checksum="F7975002A5E2A37F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD1</accession>
    <name>C7QDD1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ACU72724"/>
        <property type="gene ID" value="Caci_3823"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3823"/>
    <dbReference type="eggNOG" id="ENOG5032TBZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1169013_0_0_11"/>
    <dbReference type="OMA" id="TVIFMAS"/>
    <dbReference type="OrthoDB" id="1906761at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24239" checksum="56E28F9E23E3370A" modified="2009-10-13" version="1">MKHEATADRQFGEGPLARVTAPIYSFLVLDLLLFATTLPTLIALVVLRRDASNAPLAIACALPVGPALSAALYALSRRSPDLTDLRPAAAFWRGYRMNAGGVVRIWVPYLAGMALIAENLSHAEAAAVPGWWRAALVVLAVAATLWVINALMISSLFAFRTIDVARLSAYFLGRTRGVTLGNLGILIAAAAVVGISSEAVLALFAVLFAAALLHVCSPLTDQVEKDFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDP2</accession>
    <name>C7QDP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74666">
        <property type="protein sequence ID" value="ACU74666"/>
        <property type="gene ID" value="Caci_5808"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5808"/>
    <dbReference type="HOGENOM" id="CLU_1746340_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="13777" checksum="181496F9FFD85587" modified="2009-10-13" version="1">MLGAELFAALVGVALEVVVLAGLAAALGAESLAALEVVVVLGADPFAAPVVVLARLAAAPGAELFAALGVAASAAVSVAAVSAGAGAARFAASTGAPAVVLGAELLAALEVVASAGALAAALAVVAASCAASPLAGVGIVLLMPFSVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDQ2</accession>
    <name>C7QDQ2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase</fullName>
            <ecNumber evidence="5">4.1.1.112</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Oxaloacetate decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Regulator of ribonuclease activity homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">RraA-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5818</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + oxaloacetate = CO2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.112"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II aldolase/RraA-like family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.112" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5818"/>
    <dbReference type="EnsemblBacteria" id="ACU74676">
        <property type="protein sequence ID" value="ACU74676"/>
        <property type="gene ID" value="Caci_5818"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5818"/>
    <dbReference type="eggNOG" id="COG0684">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072626_3_2_11"/>
    <dbReference type="OMA" id="MKLCGPA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21617" checksum="229A647DD3111590" modified="2009-10-13" version="1">MDTFADVPTTALADVLTRENVMDTDIRPLTGAPGRLAGPAFTVRCPPGDNLMVHAAIYRAEPGSVIVVDTGGDVDYAVAGGNVMAVAQRRGIAGFVVDGVIRDLAEAREAGFPVFARGVIPIPGAKAVVKRHNITVRCGGVMVHPGDIVVADEEGIVVVPVARKEEVFAAARAKLAKDEAESLEDWERAHRVRIDKLLAEGGFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR7</accession>
    <name>C7QDR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5833</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5833"/>
    <dbReference type="EnsemblBacteria" id="ACU74691">
        <property type="protein sequence ID" value="ACU74691"/>
        <property type="gene ID" value="Caci_5833"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5833"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="YLHCADL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="844"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="937" mass="100726" checksum="493D785FB1CFB1D8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE16</accession>
    <name>C7QE16_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvC</name>
        <name evidence="12" type="ordered locus">Caci_7780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796329.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7780"/>
    <dbReference type="EnsemblBacteria" id="ACU76604">
        <property type="protein sequence ID" value="ACU76604"/>
        <property type="gene ID" value="Caci_7780"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7780"/>
    <dbReference type="eggNOG" id="COG0059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033821_0_1_11"/>
    <dbReference type="OMA" id="RAMFSWL"/>
    <dbReference type="OrthoDB" id="188901at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="2"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="183"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU76604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="35957" checksum="E99218C5E305BFB8" modified="2009-10-13" version="1">MAEMYYDDDADLSIIQGRSVAVLGYGSQGHAHALSLRDSGVDVRVGLHEGSKSRQAAEEAGLRVLTPFEACEEADVIMILVPDPVQRKVYAEAVEPNLAEGDAIFFGHGLNIRYGLIKPPAGVDVCMVAPKGPGHLVRRQFTEGRGVPCLIAVEQDATGTATELALSYAKGIGGTRAGVIKTTFTEETETDLFGEQAVLCGGAEALIKAGFETLTEAGYQPEVAYFECLHELKLIVDLMYEGGLEKMNWSVSETAEWGGYVTGPRIVDDRTKATMKQVLTEIQDGSFANNWIAEYDAGLPNYKKYVEAEEQHPITATGKKLRSMMSWIREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE31</accession>
    <name>C7QE31_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">whiB</name>
        <name evidence="14" type="ordered locus">Caci_7795</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7795"/>
    <dbReference type="EnsemblBacteria" id="ACU76619">
        <property type="protein sequence ID" value="ACU76619"/>
        <property type="gene ID" value="Caci_7795"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7795"/>
    <dbReference type="eggNOG" id="ENOG5032RVG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2044654_0_0_11"/>
    <dbReference type="OMA" id="CHVEDPD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="13">
        <location>
            <begin position="17"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU76619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12186" checksum="5D75E18E2410775E" modified="2009-10-13" version="1">MQNVFDTVVEQTDTTLPCRAYDPEVFFAETPTDVEFAKAICVECPVKSACLAGALERREPWGVWGGELFVQGVIVARKRPRGRPRKDAALVEAQIAAEAAAAVEAAKKVAIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE63</accession>
    <name>C7QE63_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7827"/>
    <dbReference type="EnsemblBacteria" id="ACU76651">
        <property type="protein sequence ID" value="ACU76651"/>
        <property type="gene ID" value="Caci_7827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7827"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092691_1_0_11"/>
    <dbReference type="OMA" id="NEFCVIE"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="2">
        <location>
            <begin position="8"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxalase_6" evidence="2">
        <location>
            <begin position="131"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="26048" checksum="16C540D73F4333A3" modified="2009-10-13" version="1">MAVQLVALCIDAHDPLRLARFWAGVLGWEQADDPEGIALNPNDDTGFRLRFLPSEAEKVQQNQMHFDLTSASPEMQRQTVARALELGGRHHDVGQGPDATHVVLADPEGNEFCVIAAGNKFLAECGFVGALASDGSQEVGYFWSRVLDWPLVWDQDQETAIRSPHGGPKITWGGPPFAAKPGRNRLRFDLAVVGDRQAGSGLNTELDRLVSLGAARTGAAPGPLGEVEMTDPDGNEFTVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEE7</accession>
    <name>C7QEE7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1918"/>
    <dbReference type="EnsemblBacteria" id="ACU70838">
        <property type="protein sequence ID" value="ACU70838"/>
        <property type="gene ID" value="Caci_1918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1918"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1966586_0_0_11"/>
    <dbReference type="OMA" id="DCSRVAF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="32"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="12985" checksum="BCD693E942045EA4" modified="2009-10-13" version="1">MAVEGFSVEVDNDPDRGGAAAVPGDGKDSQAVTVTVAGDVDLAAADTLWSVLDEYVRSGAQVVVDCSRVAFLDSMGLRTLIRAQHKAKASGARLTLAAPSEAVLRVLQLAGVADLFVLDVSGSGSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG1</accession>
    <name>C7QEG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1932"/>
    <dbReference type="EnsemblBacteria" id="ACU70852">
        <property type="protein sequence ID" value="ACU70852"/>
        <property type="gene ID" value="Caci_1932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1932"/>
    <dbReference type="eggNOG" id="COG2374">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003608_1_1_11"/>
    <dbReference type="OMA" id="LWVTVKP"/>
    <dbReference type="OrthoDB" id="1884225at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19580">
        <property type="entry name" value="Exo_endo_phos_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981573" evidence="2">
        <location>
            <begin position="29"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="22"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="802" mass="82062" checksum="B3DB869B80E74ABA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG9</accession>
    <name>C7QEG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786153.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1940"/>
    <dbReference type="EnsemblBacteria" id="ACU70860">
        <property type="protein sequence ID" value="ACU70860"/>
        <property type="gene ID" value="Caci_1940"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1940"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="YKIVYFF"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="71"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="35248" checksum="18D5BA50863E564C" modified="2009-10-13" version="1">MRLRKKTRERLFIASFLAGPLAVYLIFVIWPYVETFGYSLTEWSGVAPPSKVVGLKNYADLFHDSIFLKALTHNMIILIVFPTITIVLAMFFAFMLNVGGRRGGLGGVRGIGGSAFFRIVFFFPQVLSVAIIVILFQAAYESNSVGLFNAIVIKLGLTDANHPWEFLNSPTFVLWCIMFILVWQWVGFYLVLFSAAMQQIPRDYYEAALLDGAGRTQTYFKVTMPLLWDSVQTAWVYLAVAAMDAFALVATLTPGSSFGGGPDEHGEVLATYLMRNFQVLGKAGYACAMGVVIFFITLILSLVVMRLTRRERLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF32</accession>
    <name>C7QF32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArgP, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5932"/>
    <dbReference type="EnsemblBacteria" id="ACU74790">
        <property type="protein sequence ID" value="ACU74790"/>
        <property type="gene ID" value="Caci_5932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5932"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063829_0_1_11"/>
    <dbReference type="OMA" id="QQWKLDS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017685">
        <property type="entry name" value="ArgP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03298">
        <property type="entry name" value="argP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33880" checksum="A3057B46C007D69C" modified="2009-10-13" version="1">MTDLPLDHVRTLLVAVDAGTFEAAARILHVTPSAVSQRIKALEQRTGRVLLVRSKPLRPTESGVAVVRFARQLAWLEDAARAELGLAGADQADAAHDAHAADGTSAAPVQTLSIAVNSDSLSTWFPEVTARFSPEAAVCFDLHREDQDYTDELLRAGLVMAAISSSPKPVQGCVVRPLGRMRYRAVATHGFVRRWLPGGVGATDLAAALAVAPVIIFNRKDDLQDGFLRGIGAPASGPRHYLPATDAYLYAVESGYGWGLIPDVQAKQFGQVELVELAPGRPVDVPLYWQQWRLAPPMLTEVGEVAVEVAARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF70</accession>
    <name>C7QF70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794557.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5970"/>
    <dbReference type="EnsemblBacteria" id="ACU74828">
        <property type="protein sequence ID" value="ACU74828"/>
        <property type="gene ID" value="Caci_5970"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5970"/>
    <dbReference type="eggNOG" id="COG1949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064761_3_0_11"/>
    <dbReference type="OMA" id="AFFHYRN"/>
    <dbReference type="OrthoDB" id="1390327at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="23333" checksum="A13CDCD3C9889DDA" modified="2009-10-13" version="1">MSDRLVWIDCEMTGLDLDKDALIEVAVLVTDSELNVLGDGVDVVVAPPAEELPGLLEGMVEVVREMHTASGLLEELSSGIPMAEAQERVLAYVREHVPEAGKAQLAGNSVGTDRGFLARDMPELEQHLHYRIVDVSSIKELARRWYPRVYFNAPKKTGNHRALGDIRDSIAELRYYRDAIFVPQPGPDSETARTVAGRIEAEEAAAAAARAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFG3</accession>
    <name>C7QFG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796465.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7917"/>
    <dbReference type="EnsemblBacteria" id="ACU76740">
        <property type="protein sequence ID" value="ACU76740"/>
        <property type="gene ID" value="Caci_7917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7917"/>
    <dbReference type="eggNOG" id="ENOG503303Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152487_1_0_11"/>
    <dbReference type="OMA" id="TWGEMRT"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="13304" checksum="D0E4F38F0B2E62DB" modified="2009-10-13" version="1">MMPTSELVDPAVRAFVDALNANDPAAVRAALTENATMTDDGTPRLLWDWLQREAFDTHGRMDVIAQSPDGRGLIAQYTNEQWGGMMTRWRFKVAGDRIAHFDTGQAGEPPYDPASWLGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL9</accession>
    <name>C7QFL9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0003</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784253.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0003"/>
    <dbReference type="EnsemblBacteria" id="ACU68958">
        <property type="protein sequence ID" value="ACU68958"/>
        <property type="gene ID" value="Caci_0003"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0003"/>
    <dbReference type="eggNOG" id="COG1023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_0_0_11"/>
    <dbReference type="OMA" id="NGYALMY"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004849">
        <property type="entry name" value="6DGDH_YqeC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00872">
        <property type="entry name" value="gnd_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="3">
        <location>
            <begin position="160"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU68958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="292" mass="31308" checksum="12DC096E005C6AE5" modified="2009-10-13" version="1">MEIGLVGLGKMGGNMRERIRQAGHTVVGYDRDPKLADVGSLKELVQTLAAPRVIWIMVPAGEATDATVNELADLLHTGDMVIDGGNSRWTEDIKHAELLKAQGVAFVDAGVSGGVWGLQNGYALMVGGDEADIARVQPVFDALKPAGDSGFVHAGGVGAGHFSKMVHNGIEYGIMQSYAEGWELLEAAPNVTNVREVFRSWQEGTVIRSWLLDLLVRALDDDEHLAGIRGYADDSGEGRWTVEAGIDMAVPTPAITASLYARFTSRQEDSPQMKAIAALRNQFGGHAVKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG96</accession>
    <name>C7QG96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792670.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4076"/>
    <dbReference type="EnsemblBacteria" id="ACU72941">
        <property type="protein sequence ID" value="ACU72941"/>
        <property type="gene ID" value="Caci_4076"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4076"/>
    <dbReference type="HOGENOM" id="CLU_1821902_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="14851" checksum="C202A87FB76333FD" modified="2009-10-13" version="1">MAETVIPACDECGAEPGQKCGPMCTAPFGPGGPYEYMSPDDEHPAVTAAITALHAHGVSARVVSPDGRGYLLEIVPGTDGSHIWIGAPEFLPDLRWPEESATGWVANHNTDDDFIDAPYYAWDNPDPAPMAAAVAAYIAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH17</accession>
    <name>C7QH17_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796592.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8044"/>
    <dbReference type="EnsemblBacteria" id="ACU76867">
        <property type="protein sequence ID" value="ACU76867"/>
        <property type="gene ID" value="Caci_8044"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8044"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_1_11"/>
    <dbReference type="OMA" id="QYNTGRV"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="48"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="30482" checksum="E93F6C3732321DF9" modified="2009-10-13" version="1" precursor="true">MSSSTPYRPPRKQGAAFRFIVVVMVPPLRVLMKRDWRGGENIPRTGGVVIAANHISHVDALAFGHYIYGNGRIPRFLAKSGVFKNKFVGGVLRAAKQIPVYRDSADAANALRDAISAVENGQAVAVYPEGTITRDPSLWPMAAKSGAARIALATGCPVVPVAQWGPQEILAYHEKRPHILPRKRMIMLAGPPVDLDDLRAMPQTAATLREATDRIMEAITELLAKLRGEEPPAQRYASANGTDNENGTENGTENGNEYGEGEAPHGAAARGDAEGESGKQVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH48</accession>
    <name>C7QH48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate binding family 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8075"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH75">
        <property type="family name" value="Glycoside Hydrolase Family 75"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76898">
        <property type="protein sequence ID" value="ACU76898"/>
        <property type="gene ID" value="Caci_8075"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8075"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057472_0_0_11"/>
    <dbReference type="OMA" id="NGEYAED"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="PTHR42061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983224" evidence="2">
        <location>
            <begin position="31"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="3">
        <location>
            <begin position="277"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="40841" checksum="ABD0E6CE557BC670" modified="2009-10-13" version="1" precursor="true">MSSSRKRLAVAAAAAIAIATQLAITHTAQAATAHPAAKAGSAAAPAAAAADYTAAQVLAGVQKNSTSSTQVNSKPHINTMTRSMNVNVYQPAPGVYSYTSSMAIDDDGSDPDPDPDHQGETTFQDSNGAQLAAHHVPFFVLGDDCWDKKTPCPHFFYKEHGMSGRQFALMFYKGKVIGSIFGDTQTGNSQTTSDNDSRELGEASVKAASLLGIPSSGTTGGVDNGVTVVMFSGPSWVVNGSNANLSNNAQALVQKALNTLGAAMDGGGTTPPPPTGTLFEAETGSMSSGGTFDSNHTGFTGSGFANPANAAGSYLDIPVTADSAGTKTLTFRYSDGTSSARPATISVNGTSHGTLNFPVTSDWNTWSTATISVPLTAGANTIRVTGTVADGPANIDSVTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH50</accession>
    <name>C7QH50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8077"/>
    <dbReference type="EnsemblBacteria" id="ACU76900">
        <property type="protein sequence ID" value="ACU76900"/>
        <property type="gene ID" value="Caci_8077"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8077"/>
    <dbReference type="HOGENOM" id="CLU_3059781_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="53" mass="5711" checksum="4876EBA8C79A7354" modified="2009-10-13" version="1" precursor="true">MWFALILLVVMLLLSLMFGGFHKGHLHPNGLPARSVVSCVVDCPHPGSGDLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH62</accession>
    <name>C7QH62_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8089"/>
    <dbReference type="EnsemblBacteria" id="ACU76912">
        <property type="protein sequence ID" value="ACU76912"/>
        <property type="gene ID" value="Caci_8089"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8089"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025436_1_2_11"/>
    <dbReference type="OMA" id="KAYGVVR"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="512" mass="53448" checksum="0FD5591E150C33C8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHB5</accession>
    <name>C7QHB5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-oxoprolinase subunit A</fullName>
            <shortName evidence="1">5-OPase subunit A</shortName>
            <ecNumber evidence="1">3.5.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">5-oxoprolinase (ATP-hydrolyzing) subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pxpA</name>
        <name evidence="2" type="ordered locus">Caci_0099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10348"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.5.2.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex composed of PxpA, PxpB and PxpC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LamB/PxpA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784349.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0099"/>
    <dbReference type="EnsemblBacteria" id="ACU69054">
        <property type="protein sequence ID" value="ACU69054"/>
        <property type="gene ID" value="Caci_0099"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0099"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_0_0_11"/>
    <dbReference type="OMA" id="DRTYKQD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00691">
        <property type="entry name" value="PxpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="26521" checksum="D031BC492E903BF6" modified="2009-10-13" version="1">MIDLNADLGEGFGRWRLGDDDALLELVTSANVACGFHAGDPSTMRRVCAAAVSRGVRVGAQVGYRDLAGFGRRDIEYDPHELADDVLFQIGALDAFARAAGDRVRYVKPHGALYNRIVHDAVQAEAVVRAVVTFASVYDVQVPVLGLPGSVFLELATTAGLSVIPEAFADRAYTPQGTLVSRSKPGAVLTTPEEVAGRAVEMAVSGTVRAIDGTLVNVSARSLCVHGDSPSAVAMAAAVRDGLRSVGVEVGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHE2</accession>
    <name>C7QHE2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0126"/>
    <dbReference type="EnsemblBacteria" id="ACU69081">
        <property type="protein sequence ID" value="ACU69081"/>
        <property type="gene ID" value="Caci_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0126"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068063_0_0_11"/>
    <dbReference type="OMA" id="TTHAQHG"/>
    <dbReference type="OrthoDB" id="191097at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="29759" checksum="1403B7CB72B23789" modified="2009-10-13" version="1">MSTSRVLVIGIDGTRLDFLDAEPTPNIDRVAGEGFLATVWVEDGTPTVSGPCWATAVTGTTIERHHIGSNDFAGHRLAEHPDFLTVLTRDFGLHTYLAVGAWPPLATPADHGPMFAAPSRLTFATFGQSAQACDQGDETITRDAERILATENIHAAFVYLGANDATAHDQGCGDLYRTAIRRTDARTGRLLAAVASRPDRATENWTFILLTDHGHLPEGGHGGTTTPERTAWIAACGPGIQAGADYGTLRHVDVAAHVYAALGVEPEIVLDGKAFQTMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHF2</accession>
    <name>C7QHF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ig family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784386.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0136"/>
    <dbReference type="EnsemblBacteria" id="ACU69091">
        <property type="protein sequence ID" value="ACU69091"/>
        <property type="gene ID" value="Caci_0136"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0136"/>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021515_0_0_11"/>
    <dbReference type="OMA" id="YDWATAT"/>
    <dbReference type="OrthoDB" id="427639at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982883" evidence="1">
        <location>
            <begin position="37"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="CADG" evidence="2">
        <location>
            <begin position="387"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="622" mass="62938" checksum="1DB5A8E7473EA47D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHK5</accession>
    <name>C7QHK5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786323.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2111"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71030">
        <property type="protein sequence ID" value="ACU71030"/>
        <property type="gene ID" value="Caci_2111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2111"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_3_11"/>
    <dbReference type="OMA" id="QAFNFQF"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="34"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="555" mass="60405" checksum="C13467C17711ED2C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHY2</accession>
    <name>C7QHY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792756.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4163"/>
    <dbReference type="EnsemblBacteria" id="ACU73027">
        <property type="protein sequence ID" value="ACU73027"/>
        <property type="gene ID" value="Caci_4163"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4163"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_3_11"/>
    <dbReference type="OMA" id="HTIGMEI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="144"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1039" mass="111796" checksum="2D11FACA6596B193" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHY6</accession>
    <name>C7QHY6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ig domain protein group 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4167"/>
    <dbReference type="EnsemblBacteria" id="ACU73031">
        <property type="protein sequence ID" value="ACU73031"/>
        <property type="gene ID" value="Caci_4167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4167"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4632">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004974_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983148" evidence="2">
        <location>
            <begin position="33"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="516"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1164" mass="119841" checksum="7A10DD24E29074BA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI94</accession>
    <name>C7QI94_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792868.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4275"/>
    <dbReference type="EnsemblBacteria" id="ACU73139">
        <property type="protein sequence ID" value="ACU73139"/>
        <property type="gene ID" value="Caci_4275"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4275"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_1_0_11"/>
    <dbReference type="OMA" id="GRIQFIA"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="22256" checksum="DE05F6CBB136B1FC" modified="2009-10-13" version="1">MNTFATPEPVLVVLDIPAGRVRLVAGERAESTVEVLPAESSKKRDVKAAEQTAVEYSDGILRITTAEASRFLGSGSVDVTVQVPAGSRVEGKAAAAELYGTGPLGEVVFDGAYRLVDLAEVAGARLTVHSGSVAIGRLTGSAQISNGTGDITIAEAVAGVVELRTEAGNVTVHAARGVSATLDAGTSRGRITNALKNGDGADAALTIKATASAGDITATSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ34</accession>
    <name>C7QJ34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0223"/>
    <dbReference type="EnsemblBacteria" id="ACU69176">
        <property type="protein sequence ID" value="ACU69176"/>
        <property type="gene ID" value="Caci_0223"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0223"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441258_0_0_11"/>
    <dbReference type="OMA" id="LWEQGRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="619" mass="67341" checksum="7B52433A629552D8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ84</accession>
    <name>C7QJ84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784521.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0273"/>
    <dbReference type="EnsemblBacteria" id="ACU69226">
        <property type="protein sequence ID" value="ACU69226"/>
        <property type="gene ID" value="Caci_0273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0273"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_554005_0_0_11"/>
    <dbReference type="OMA" id="KCASGQV"/>
    <dbReference type="OrthoDB" id="1992532at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="492" mass="53393" checksum="AD68C598F0E38C7C" modified="2009-10-13" version="1">MSHEVVFLPHILGQTWAQALAAARTAAREEDPRIVAARLEPWPDLVLHAAQILGQIEEFRGRGQRELVHPVTRLRFTFFGEDGVIALPYWYDGPVARMAATMAFRFAHAVESDTGLAAYDPQLRTPLSEMGLEKFVAGYLRGRERALGQAQARGPVPVGHALPAGRSATRRELAAGPSAGRGAGFDGGGSGGPGAPGASGGAGARQGADSSRPPREVARSPREPKAAPRQNTDVRPGPDASRPTDPARLRPAGPVRGADAAGREAQARPRPNSDQRQPANPVRRENKDARQAADSGPIAGSGGWLRRGKPARGEQVPRTGGVAEPRKAPRRGEPLDADPSQRSRGPREPKAPRRGEPIDVDPSQRSRRPPEAKSPRRDESGEAQRPRRDPEPRAPRRGDRPDAEQAQRSGKVVPPKKLSRRERAEAERAQRAQQARQAQQAKRGPVPPPETGTEWVPRPGRPEPPEPRRAPPPERDRRQPPEPPQQQPRSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM4</accession>
    <name>C7QJM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2329"/>
    <dbReference type="EnsemblBacteria" id="ACU71247">
        <property type="protein sequence ID" value="ACU71247"/>
        <property type="gene ID" value="Caci_2329"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2329"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_6_3_11"/>
    <dbReference type="OMA" id="TQMEAFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019923">
        <property type="entry name" value="Lucif-like_OxRdtase_MSMEG_2516"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03621">
        <property type="entry name" value="F420_MSMEG_2516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="36359" checksum="C06761C14FC3AF7D" modified="2009-10-13" version="1">MSGPAPGHASGHDQPQQAAVGKDGGMRPFRFLATIADDDDILDLIPLARRAEAMGCHGFVIPDHLMSPAPLLPLAQVAAVTERLRVGTFVLNNSLRHPAVLAQELATLDRLSGGRLDIGIGAGWNKPEYDAIGIPFEPVGVRIKQLTEALAIIKGCFAEGAFSFAGEYYTITDLDGAPAPVQRPHPPFFLGGGGKRFLTLAAREAQVIGLAPRLLGGDVPRLDAPSITAAATEEKIGWIREAAGERFAEIELNAYPTGGPSVVTTEPRIEAQRRVDRIREQTGVELTVEDILESPHSYIGTVKDLIAKFLELRERFGISSFLIDDLDRLAPVVEALAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJR9</accession>
    <name>C7QJR9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lysine N-acyltransferase MbtK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mycobactin synthase protein K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis; mycobactin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792886.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4293"/>
    <dbReference type="EnsemblBacteria" id="ACU73157">
        <property type="protein sequence ID" value="ACU73157"/>
        <property type="gene ID" value="Caci_4293"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4293"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039848_5_1_11"/>
    <dbReference type="OMA" id="DVGMHFL"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="UniPathway" id="UPA00011"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlcB" evidence="5">
        <location>
            <begin position="5"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="20437" checksum="4130C69DA9A7D00E" modified="2009-10-13" version="1">MISFRPVDVDSDAEMEMLHRWVTHPKAAFWLMQDFDVEQVREEYRRISEHPHHEAFLGLVDGNPAFLAERYDPGHVELVGLYEPEDGDVGMHFLCAPTDTPVHGFTRTVITAVLAWIFADPDALRVVVEPDVRNTAVHALNAAVGFRVVGPIAKPEKQALLSVCTWHDFQSATSALPRLGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK63</accession>
    <name>C7QK63_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6283</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794866.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6283"/>
    <dbReference type="EnsemblBacteria" id="ACU75137">
        <property type="protein sequence ID" value="ACU75137"/>
        <property type="gene ID" value="Caci_6283"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6283"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="PLRETFH"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1022" mass="110257" checksum="8BFC8F2B23BBBC82" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK84</accession>
    <name>C7QK84_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="1">AGPR</shortName>
            <ecNumber evidence="1">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argC</name>
        <name evidence="3" type="ordered locus">Caci_6304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794887.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6304"/>
    <dbReference type="EnsemblBacteria" id="ACU75158">
        <property type="protein sequence ID" value="ACU75158"/>
        <property type="gene ID" value="Caci_6304"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6304"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_1_11"/>
    <dbReference type="OMA" id="GTHHPTR"/>
    <dbReference type="OrthoDB" id="951261at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37109" checksum="D7D421391B376C77" modified="2009-10-13" version="1">MVRVTVAGAAGYIGGELLRLLLGHPEIEVVGAVSSRFPGRRIDGVHPNLRSATDLSFCATEDVPESDAVFLALPHRVAMTQIEQWTQRSKLVIDLTGDFRLDDTAVYERYYDEEHQAPHLLDEFTPGLPELYRDQLRTADLISVPGCMATAGVLALYPLVAHDLIDPEQGAQFDARTGSSGSGATAGPANLHAERSGAMRVFAPTRHRHEAEISRHLGLSAAMTATGVEAVRGAQSLCHATLREGVDEQQVRRAFRRQYSAEPFVRVVAHQRGIHRYPDPKILLGSNFCDVGFAVDADTGRLTTIAALDNLVKGGAGNALQCLNIRLGLPETLGLSFPGLHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB9</accession>
    <name>C7QKB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794922.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6339"/>
    <dbReference type="EnsemblBacteria" id="ACU75193">
        <property type="protein sequence ID" value="ACU75193"/>
        <property type="gene ID" value="Caci_6339"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6339"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="MGRWHHE"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="31809" checksum="C860E50383C6D211" modified="2009-10-13" version="1">MILVTGATGNIGRELVRELAEKGVDFRILVRDPARAAGLLGAADHGKRADHASHAEQPELAVGDLSDPATLTPAFAGVDKLFLLTPGIGTEHTAHAVAAARDAGVRRIVHLSSFNVLGDPMPAMGRWHHEREQIVRDSGIPATFLRPGGFMSNAFDWLPTIRAGGYVLDPTGPGRYAAIDPADIAAVAALVLTEDGHEGNSYVPTGDEPMTVAEHVRILAAATGLAIDVREAATPAEAVQARFPHGAPPALAAAITEGFALMRADTQGFRTDTVEKLLGRKPKSFADWCARNAEVFRGESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR9</accession>
    <name>C7QKR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8345"/>
    <dbReference type="EnsemblBacteria" id="ACU77168">
        <property type="protein sequence ID" value="ACU77168"/>
        <property type="gene ID" value="Caci_8345"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8345"/>
    <dbReference type="HOGENOM" id="CLU_198288_0_0_11"/>
    <dbReference type="OMA" id="VVVEPWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="8935" checksum="DA043F8F37307F86" modified="2009-10-13" version="1">MRKVPDEAVIGCVGELHVGTRGARGPGEAVVRVRGGTEAFLAWSEQPLPKGTRILVVESRGQRAVDVIAFPESTDPLDELDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVC9</accession>
    <name>C7PVC9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_0332</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 12"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784580.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0332"/>
    <dbReference type="EnsemblBacteria" id="ACU69285">
        <property type="protein sequence ID" value="ACU69285"/>
        <property type="gene ID" value="Caci_0332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0332"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005373_0_0_11"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 12" id="KW-0639">Primosome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="13">
        <location>
            <begin position="192"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU69285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="460" mass="50639" checksum="F9816FBF84CE0156" modified="2009-10-13" version="1">MSIDDLPYTADEAYQGGFERTPPQDIPAEQSVLGGMLLSKDAIAEVIEVIKAIDFYKPAHEAVFGAILELYGRGEPADPVTVAALLTKKGDINRIGGAPYLHTLINSVPTAANAGYYAEIVKERAVLRRLVEAGTRIVQMGYSTDGSDVEQIVDAAQQEMYNVTEARTSEDFIPLADAMEGALDEIESISNRSGQMTGVPTGFHDLDALTNGLHPGQMVIIAARPAIGKSTLGLDLARSCSIKNGLTSVIFSLEMGRNEIIMRLLSAEARVALHHMRSGTMTDEDWARLARRMGPVSEAPLFIDDSPNMSMMEIRAKARRLKQRHDLQLVIIDYMQLMQHSSSNSKRPDSRQQEVSEISRSLKLLAKELEVPVIAISQLNRGPEQRTDKRPMMSDLRESGSLEQDADVIILLHREDAYERESPRAGEADLIVAKHRNGPTANITVAFQGHYSRFVDMAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVG6</accession>
    <name>C7PVG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784617.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0369"/>
    <dbReference type="EnsemblBacteria" id="ACU69322">
        <property type="protein sequence ID" value="ACU69322"/>
        <property type="gene ID" value="Caci_0369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0369"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_6_11"/>
    <dbReference type="OMA" id="IEDRWQI"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9846" checksum="0BB3F774F24F0AD7" modified="2009-10-13" version="1">MESYQHVLDTLRVIIEGSVDEVAAGDITADSDLAGELGVDSLAMFEIADKAQERWNIKISDDDISRFTTVESLATFIQAAVGAQGLPAMTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVS8</accession>
    <name>C7PVS8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydroorotase</fullName>
            <shortName evidence="5">DHOase</shortName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrC</name>
        <name evidence="7" type="ordered locus">Caci_2402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786613.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2402"/>
    <dbReference type="EnsemblBacteria" id="ACU71320">
        <property type="protein sequence ID" value="ACU71320"/>
        <property type="gene ID" value="Caci_2402"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2402"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_1_0_11"/>
    <dbReference type="OMA" id="QHAQEPR"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00220_B">
        <property type="entry name" value="PyrC_classI_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="48"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="59"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="430" mass="44899" checksum="D5DE6F5A5C7C55EC" modified="2009-10-13" version="1">MSTTYLIKNASVLGGDPQDLLLRDGIIADAGALGPVAGTVVIDAGGLIALPGLVDLHTHLREPGREDAETVDTGTRAAALGGFTAVHAMANTDPVADTAGVVEQVWRLGREAGHCDVFPVGAVTVGLAGERLAELGAMADSAARVRVFSDDGKCVSDANLMRRALEYVKAFDGVVAQHAQEPRLTEGAQMNEGELSGILGLTGWPAVAEEAVIARDILLAAHTKSRLHVCHVSTAGSVELIRWAKSKGYPVTAEVTPHHLILTEDLVKSYDPIYKVNPPLRTAADVEALRAGLADGTIDAVATDHAPHPQEDKDCEWAAAAMGMLGLETALSVVQQTMVDSGLMSWAGVADRMSVRPAAIGQVEDRHGRPLAIGEPANLVLVDPAAKRTVDRTGLASLSQNTPYQGMELPGAVVATFLRGTATVLDGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW02</accession>
    <name>C7PW02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786687.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2476"/>
    <dbReference type="ESTHER" id="catad-c7pw02">
        <property type="family name" value="NLS3-Tex30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71394">
        <property type="protein sequence ID" value="ACU71394"/>
        <property type="gene ID" value="Caci_2476"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2476"/>
    <dbReference type="eggNOG" id="COG3571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072792_3_0_11"/>
    <dbReference type="OMA" id="HSFKPRK"/>
    <dbReference type="OrthoDB" id="1090356at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="21707" checksum="53104026FC40209F" modified="2009-10-13" version="1">MQELITTPVGDARLTRFPTPSRVKRRAVLALGHGAGGGIQAADLQAIAGALPASGVEVVLVEQPWVVAGKKIAPAPKTLDAGWVPVAEVVRKRARSTPFLVGGRSAGARVACRTGLVSGAVGVVALAFPLHPPGKPEKSRAGELLGSGLPTLVVQAGADTFGTAAEFPSLPATHRLVGLVAGDHAFKVRKVDPPVLDALVAAVVEWTGELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW57</accession>
    <name>C7PW57_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4441"/>
    <dbReference type="EnsemblBacteria" id="ACU73305">
        <property type="protein sequence ID" value="ACU73305"/>
        <property type="gene ID" value="Caci_4441"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4441"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009398_1_1_11"/>
    <dbReference type="OMA" id="MIAWCHG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="104"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="959" mass="101828" checksum="0E01C4055916DBAA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW63</accession>
    <name>C7PW63_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793040.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4448"/>
    <dbReference type="EnsemblBacteria" id="ACU73311">
        <property type="protein sequence ID" value="ACU73311"/>
        <property type="gene ID" value="Caci_4448"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4448"/>
    <dbReference type="eggNOG" id="COG3826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073550_0_0_11"/>
    <dbReference type="OMA" id="MARHRFG"/>
    <dbReference type="OrthoDB" id="1025956at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018655">
        <property type="entry name" value="DUF2086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09859">
        <property type="entry name" value="Oxygenase-NA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="117"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="25752" checksum="D53043F27BA872E9" modified="2009-10-13" version="1">MPALTDADWPTIAAELDSSGCAPTPRLLTPEQCGGIAALYDRPELFRTTVDMARHRFGSGQYRYFTHDLPAPIAALRRALWPHLLPIARDWAERLGRPAPWPDDLDEWLERCHAAGQARSAQILLRYGPGDWNALHRDVFGDMLFPLQAVIGLDAYGTDYTGGEFLLVEQRPRAQSRGTATPLPQGHALIFTTRDRPVRSSRGWSIGPVRHGVSTVRSGQRRALGLVFHDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW88</accession>
    <name>C7PW88_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translation elongation factor G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4473</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
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    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="entry name" value="EFTu-like_2"/>
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        <property type="entry name" value="G_TR_CS"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
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        <property type="entry name" value="Small_GTP-bd_dom"/>
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        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
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        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
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        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
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        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
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        <location>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU73336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="677" mass="70910" checksum="38D6946FD1A452A8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWL9</accession>
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        <submittedName>
            <fullName evidence="2">Xanthine/uracil/vitamin C permease</fullName>
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        <name evidence="2" type="ordered locus">Caci_6447</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU75299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6447"/>
    <dbReference type="EnsemblBacteria" id="ACU75299">
        <property type="protein sequence ID" value="ACU75299"/>
        <property type="gene ID" value="Caci_6447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6447"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_020957_1_0_11"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016021">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
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            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
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        </location>
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        <location>
            <begin position="233"/>
            <end position="256"/>
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    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="530" mass="55379" checksum="3CDAB80F85B0DE9C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY5</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Caci_8419</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            <dbReference type="PubMed" id="21304647"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="139"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14607" checksum="81F80DC224C12896" modified="2009-10-13" version="1">MQRLLDGEPTPPILPGQRAAKPLDPLQAARAVMFAKASSMVGAIVSGVYAGYGVFLLGKLDIDVYRTRAIVCGITVLCGLALVAAALFLEYVLRVPPSGPEDGLPKDGSKSKSATAARPVRNRPDGTFPVRRTSNRSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY7</accession>
    <name>C7PWY7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8421"/>
    <dbReference type="EnsemblBacteria" id="ACU77244">
        <property type="protein sequence ID" value="ACU77244"/>
        <property type="gene ID" value="Caci_8421"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8421"/>
    <dbReference type="eggNOG" id="COG1539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112632_1_1_11"/>
    <dbReference type="OMA" id="GHYKSVA"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="16008" checksum="6C6884D7620A1171" modified="2009-10-13" version="1">MFVMMSTHTKRLDRVTVHGLRGRGHHGVFEREREKGQTFMVDVTLGLDTSRAAASDALADTVNYGEVAERIVALIEGEPVNLIETLAARMAAACLEYPLVEEVEITLHKPDAPITVPFEDVTVTVVRTREDLAVATARPPENGGSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX67</accession>
    <name>C7PX67_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784713.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0466"/>
    <dbReference type="EnsemblBacteria" id="ACU69418">
        <property type="protein sequence ID" value="ACU69418"/>
        <property type="gene ID" value="Caci_0466"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0466"/>
    <dbReference type="eggNOG" id="ENOG5034769">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2275908_0_0_11"/>
    <dbReference type="OMA" id="IGRRRYP"/>
    <dbReference type="OrthoDB" id="1890206at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9189" checksum="D5CF1760DABB38F6" modified="2009-10-13" version="1">MRFTIAGCSFHLQASDVEQAMSGIKGEPISGACVRIGRRWYPVKQVGAVITGQDRRDFSGAEVTHALERLGYTCRPTPPDAPAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX76</accession>
    <name>C7PX76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784722.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0475"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69427">
        <property type="protein sequence ID" value="ACU69427"/>
        <property type="gene ID" value="Caci_0475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0475"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049732_0_0_11"/>
    <dbReference type="OMA" id="QVDAGMW"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982642" evidence="2">
        <location>
            <begin position="39"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="4">
        <location>
            <begin position="43"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="244"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="34512" checksum="01CCE6FA8058EA18" modified="2009-10-13" version="1" precursor="true">MRIRPRSWRRSLTSGLAAAALALAGALTVGVGAPVAHAATCGGYVGLSFDDGPSNDHTPAILNALKQNGLRATMFNEGQYAAAYPAQVQAEINAGMWVGNHSYTHPHLIQESQAQIDSEVSRTQQAIAAAGGGTPTLFRPPYGETNSTLRAVEAKYGLTEIIWDIDSQDWNGASVSAIVAANGRLTNGQVILMHEWPANTLAAIPQIAQVLASHNLCPGMISPQTGRAVAPTGGSGGGGGGGGGGGGGGSCTATLSAGSQGSNWYNLNVAVTGSSTWTVTMNMVSPAVVYNTWNVSATWPSQYVMVAKPNGSGNNFGVTITPNGQWTWPSVSCSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXM3</accession>
    <name>C7PXM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786769.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2558"/>
    <dbReference type="EnsemblBacteria" id="ACU71476">
        <property type="protein sequence ID" value="ACU71476"/>
        <property type="gene ID" value="Caci_2558"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2558"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="PDWNINF"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="31073" checksum="A075079ADE73C291" modified="2009-10-13" version="1" precursor="true">MTTHPTTWFITGSSRGFGRSLATAALAAGDTVVASARKPEQLADLVAEYGERILPVALDVTDAAAAEAALAAGLEKFGRIDVVVNNAGYANLSPVETTDEADFRRQFDTNFWGVYNVSRAALPLLKKQGAGIVIQFSSIGGRVGQNPGLGSYQAAKFAVDGFTRVLAAETAPFGIRYVVVEPGGFATDWAGSSMRVEEVTDDYRQTVGVLVDRVRSGGTAQGDPDRAAEILVRMVHAGNLPTHLVLGAGAVQMALDYSRSQIAEADAWQAVSASADFGADHPVELPEVPKAPDHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY13</accession>
    <name>C7PY13_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Terpene synthase</fullName>
            <ecNumber evidence="2">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4612"/>
    <dbReference type="EnsemblBacteria" id="ACU73473">
        <property type="protein sequence ID" value="ACU73473"/>
        <property type="gene ID" value="Caci_4612"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4612"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047127_0_0_11"/>
    <dbReference type="OMA" id="VDGNHHW"/>
    <dbReference type="OrthoDB" id="1869158at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="42478" checksum="FD9E2302DB0517FA" modified="2009-10-13" version="1">MTLIADTGRSAAAVLPGLAALTGPPPARPPWEAAAPEARSEHWHSSDVDPGPESPARPPQHPERLAPAPIELRAWGDGSHSPLYCPAPSRLDEALAADVNARLVAWAERIGLHAGHLEEFAKTGFGRLITLAHPECDDPDLLLVSAQMNAAWWASDDYYADETDLGAVAEALPERLALVSSALDPPPPVGEFTPPLQDAVVSDPVLVSLRSALAHVTRHASAAQVMRVRHTTHQMYVSWNAYNAWRHAGITPQAWRYLAARQHDSFYTSMILIDVVGGYELPPELFAEPLFHRALTQAGTAAVLVNDLASAAREAGEDPDCNLVLLLAAERDCSIAEATEQVVALHNDVVRGFEHSRAALAAVPSPELQRFVLGARAWMGGCLEWHDNSSRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY41</accession>
    <name>C7PY41_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793230.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4640"/>
    <dbReference type="EnsemblBacteria" id="ACU73501">
        <property type="protein sequence ID" value="ACU73501"/>
        <property type="gene ID" value="Caci_4640"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4640"/>
    <dbReference type="eggNOG" id="ENOG502ZU1W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_610711_0_0_11"/>
    <dbReference type="OrthoDB" id="1581446at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="44997" checksum="AF2A966C1058C2DF" modified="2009-10-13" version="1">MSSTSAVSVLAQGLRELRDFAEGPDGEELGERTGLTAQQIDTALAGEHLPTREVTLALVEAWEGDVEAWREYWGQIADLAEEDGSGDGDTETPAPPEPSIITPMVTESTEHAGEGEAEVADEPETEDLEDGDADSETEAAEVAGAEDASAEAAAEAELVGEAAEAQDGAGSAQVAARAGDADELGSAKSIAETSALSQVVAASDHPPARADTTGQPPKKSMLARIGIPVLLFAVGVGVGAFGDHALNSKPSSTTSAASIPPVAGSPSRSSHTVALSPSASGSGGVSSGPTGTPSGAGSDPTGSGSESGGATSGSTSSTVVPGTVLGAYVGIQLASGYSVNFLTDPYHPAAGTADGTDTMGFFAGSFVDGRFYASRVAILAATDTGSFTSCLNDTRYQHDVLLSQIAVGSSFCITTDTGHLVLVTVRRMPSSTDANPYAVVDVTVWQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ25</accession>
    <name>C7PZ25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, CdaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784876.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0645"/>
    <dbReference type="EnsemblBacteria" id="ACU69581">
        <property type="protein sequence ID" value="ACU69581"/>
        <property type="gene ID" value="Caci_0645"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0645"/>
    <dbReference type="eggNOG" id="COG3835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_7_2_11"/>
    <dbReference type="OMA" id="ALCTVPW"/>
    <dbReference type="OrthoDB" id="1452079at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="158"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="319"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="42569" checksum="EC7DC1EA329EDBDF" modified="2009-10-13" version="1">MATPTTDQLQDLVDLISQLASSSATLEDRDFDLVAFASQSGGLDVIRQRSILQRRSTPEVRAWFEGFGIARSELPVRTPADPEHGVLPRVCLPARWNGVTYGYVWLLDVDGHLDDALLASAMHEASRAGALLAQQARVRERMEERLQNLLSPDRAVAEQAAEEISDLGLVDRDRKITVVVLETRNQDWQSVPLNLWRLPRSVLAAPETDHISLLVPEPHSVADIAERALELYRERLESDARKDVLVGIGAPREDLAEARASWREARLAVRVGRAVPTFRPTAVWADLGIYRLLACGPQRELRDAVVDPAVRRLLEEPDLLITVQTYLDHAGSAQQTAAALSIHRQTLYHRLEKIERITGLDLADGRDRLRLHLGVSLAPLVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ87</accession>
    <name>C7PZ87_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_2627</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="9">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="8">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786837.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2627"/>
    <dbReference type="EnsemblBacteria" id="ACU71544">
        <property type="protein sequence ID" value="ACU71544"/>
        <property type="gene ID" value="Caci_2627"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2627"/>
    <dbReference type="eggNOG" id="COG3733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_11"/>
    <dbReference type="OMA" id="RYWQNYF"/>
    <dbReference type="OrthoDB" id="127911at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary amine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="PTHR10638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="SSF49998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="SSF54416"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0186">Copper</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Cu_amine_oxidN3" evidence="11">
        <location>
            <begin position="104"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Cu_amine_oxid" evidence="10">
        <location>
            <begin position="226"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="7">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="8">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="644" mass="70893" checksum="C7FF82A187E12032" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE2</accession>
    <name>C7PZE2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786892.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2683"/>
    <dbReference type="EnsemblBacteria" id="ACU71599">
        <property type="protein sequence ID" value="ACU71599"/>
        <property type="gene ID" value="Caci_2683"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2683"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_11"/>
    <dbReference type="OMA" id="AMQPERT"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="46"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="131"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="36700" checksum="A2A4C71535B46B88" modified="2009-10-13" version="1">MALEPPRRPAALAMRPTVAAALFTGQNRSRLMDLVDVDPDLVLEDLHSADARSALADAEVLITGWGCPPIDEPALLAAPRLRAVVHTAGSVKDIVTEACWRRGIQVASAASANAVPVAEYTVAAILFANKQVLNARDDYARLRDQDTDWHARLAVAGNYRRRVGIVGASRIGRRVIALLRGFDLEILLTDPYLHPDEADRLGARLTGLPELFAACDTISIHAPLLPQTAGMITRALLAAMPDGATLINTARGDLIDQHALEEELLSGRLSAVLDVTTPETLPASSPLYTLPNVLLTPHIAGSMGNELQRMAHFALDELECWTKGEPFNDPVYRAALERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZH6</accession>
    <name>C7PZH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-hydroxycyclohexanecarboxyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786926.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2718"/>
    <dbReference type="EnsemblBacteria" id="ACU71633">
        <property type="protein sequence ID" value="ACU71633"/>
        <property type="gene ID" value="Caci_2718"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2718"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1068293_0_0_11"/>
    <dbReference type="OrthoDB" id="1731888at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="25867" checksum="88A23C1141117344" modified="2009-10-13" version="1">MTGLTAAAGQTGALSRMAVVAGGACDTGLAAALQLAELGLDVALIGADVAVPVEVTERFFAGGRHCLAIRADLADGRSFAAALGGARSVLGSPSVLVNCVPLGGPEPLSAEERYADARRSLRALFACCRAVCAHMVRNRWGRIVNIAQPAVADGAADREWRDGQTVLGGLVGFTRSAALELAAYGVTANYIAPSSCYPAGPAHAPAPPPAAAAGGGGTGPSYAAGVAALTGFLISDQASAITGQGGYLAGRPAAPSARWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP0</accession>
    <name>C7PZP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar isomerase (SIS)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793284.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4694"/>
    <dbReference type="EnsemblBacteria" id="ACU73555">
        <property type="protein sequence ID" value="ACU73555"/>
        <property type="gene ID" value="Caci_4694"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4694"/>
    <dbReference type="eggNOG" id="COG2222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_4_0_11"/>
    <dbReference type="OMA" id="YFIARAY"/>
    <dbReference type="OrthoDB" id="1046291at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="26"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="31461" checksum="8F25E251315BC2C5" modified="2009-10-13" version="1">MSSFVTAELADQPRSWQRAADLAATAAGLPEPGERVAVVGCGTSWFMAQAYAGLREASGAGETDAFTASELPGGREYDRVLALSRSGTTTEVLDVLAAATAPTTLITGVADSPAPALAGTAVVLDFADERSVVQTRFATTTLILLRAHLGEDVSGAIADAASAVSEPLPEGVADRTQFTFLGAGWTTGLAAEAALKMREAALAWSESYPAMDYRHGPIAITDEQSAVWMFGAAPDGLAEQVGATGGMWIHQDLDPLASLVQAQRLALELAVRRGLDPDAPRHLTRSVILRPQGASAASQSTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q010</accession>
    <name>C7Q010_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6657"/>
    <dbReference type="CAZy" id="GH55">
        <property type="family name" value="Glycoside Hydrolase Family 55"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75503">
        <property type="protein sequence ID" value="ACU75503"/>
        <property type="gene ID" value="Caci_6657"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6657"/>
    <dbReference type="eggNOG" id="ENOG502Z7WW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013797_1_0_11"/>
    <dbReference type="OrthoDB" id="352760at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980497" evidence="1">
        <location>
            <begin position="35"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="645" mass="67153" checksum="CE055CDF61FAEA11" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0I5</accession>
    <name>C7Q0I5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LUD_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8703"/>
    <dbReference type="EnsemblBacteria" id="ACU77518">
        <property type="protein sequence ID" value="ACU77518"/>
        <property type="gene ID" value="Caci_8703"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8703"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107893_0_0_11"/>
    <dbReference type="OMA" id="PCESVRA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="23"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22263" checksum="A1B2A7D0CD1F2D72" modified="2009-10-13" version="1">MNDSQTITAPSGEFAVPATADRLERAAAALRSGGFSVEILADVVAARIRLKELIPEGATVFTGASETLRQSGIDDDINASGQYDAVRPRALAADRATQADEIRRMCAVPDYVVNSVAAVTETGSLILASGTGSQLPASAGGAAHAIWIVGAQKVVPDLDAALRRVEEHSLPLESARTMAAYGSPSMVSRLLILNRELIPGRGTVLLLREAIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Y8</accession>
    <name>C7Q0Y8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786956.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2750"/>
    <dbReference type="EnsemblBacteria" id="ACU71663">
        <property type="protein sequence ID" value="ACU71663"/>
        <property type="gene ID" value="Caci_2750"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2750"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_0_11"/>
    <dbReference type="OMA" id="NTAGLNQ"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="22"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="501" mass="52978" checksum="A3536B370FFC37E6" modified="2009-10-13" version="1">MSVHDVLSRGTPNPLRNQRVVIPIMSVFTIFMVIVDGSITTVALPSLARQFHLSPAGLDGVVVIYPICLGMVIPTSAWLLERHDGRRVLLLGLALFTLASGLCGAAENLQQLIVFRALQGLAAGALMPVSQALIFRTFTQHEQIRLSRITIIPQQLAPAIAPLLGGSLVVAFSWRWVFYANVPVGLAAVVFGLLFLGEHREHRAARLDLAGLLLSAAAMGSLMYGVCAGPDHGWATPAVISALMGGAALLGLAIRHQLRTDQPALRLRLFADRLFRKACLVGLVGLIPTMGTMFLIPLFLQQAQGRDAFASGSATFTEAFGVLLTMQAVGVLYQRVGPGPIIGGGLLGVAVVELLFATCDADTGLWTLRLYMFLLGVMMGAFFIPVTLASLTTLDRADSAQAATLGTVVRQFGMALAPTVVTTVLVLDSGHGGHADISTPVAGYQKAFLVLAAIALFTGLYAFSLGRQRRMPEAESTGTANVHAAGAAQGVRQALTARTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C6</accession>
    <name>C7Q1C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793384.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4794"/>
    <dbReference type="EnsemblBacteria" id="ACU73655">
        <property type="protein sequence ID" value="ACU73655"/>
        <property type="gene ID" value="Caci_4794"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4794"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="VDLWQVH"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="15"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36355" checksum="70A7A99829688B08" modified="2009-10-13" version="1">MEQRHLGRTGLRVSRLGLGTMTWGRDTDEHEAADQLKTFLDAGGTLIDTADVYGDGDAEYIIGRMVEGIRSDVVIATKAVSVPFGPRRFDASRRHLLNALDGSLKRLGTDYIDLWQLHAYDAATPLEETLAALDTAVSSGKARYVGVCNYTGWQLARAATWQSADFSRAPIASAQMEYSLLQRGVEREVQPAAVDLGIGLLPWSPLGRGVLTGKYRSGVPADSRAASPVFAPFVDQYLDGPSDGIVDAVMIASDGLGVAPLEVALAWVRDRAGVTAPIVGARTVAQLRGCLSAEQLTLPREIREALDDVSEPDIGYPEHTWQPARPRLVNQHSHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1M6</accession>
    <name>C7Q1M6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vanillate monooxygenase</fullName>
            <ecNumber evidence="6">1.14.13.82</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.13.82" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793484.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4895"/>
    <dbReference type="EnsemblBacteria" id="ACU73755">
        <property type="protein sequence ID" value="ACU73755"/>
        <property type="gene ID" value="Caci_4895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4895"/>
    <dbReference type="eggNOG" id="COG4638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039484_0_0_11"/>
    <dbReference type="OMA" id="HAGKGGY"/>
    <dbReference type="OrthoDB" id="691776at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018489">
        <property type="term" value="F:vanillate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044043">
        <property type="entry name" value="VanA_C_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19112">
        <property type="entry name" value="VanA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="10"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="37059" checksum="629AD5CB1433BC79" modified="2009-10-13" version="1">MATAFARNQWYVAAYASEVGRTFLARTILGEPIVFYRTGQDGRAVALADRCVHRRYPLSESRLDGDTIVCGYHGFTYDTSGTCVFVPGQQRIPRTARVASYPVAELDSFVWVWIGDPELADDKLIPRAPHMADPEFVTVSGMEPIDCDYGLLVDNLLDLSHETYLHGGYIGTPEVADTPITTDADEQAGIVRVARHMVDAACPPFYAKSTGIQGRITRLQDIEYFAPCLYLLHSRITPAGEQNPLFRTEITYAITPSAPGQVYDFWAVSRNFATDDPAVTEFLRDFNHQVVMQDVVALNILQKALDSESAGYQELSIGIDAGGLAARRILAQLAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Q7</accession>
    <name>C7Q1Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795337.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6763"/>
    <dbReference type="EnsemblBacteria" id="ACU75608">
        <property type="protein sequence ID" value="ACU75608"/>
        <property type="gene ID" value="Caci_6763"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6763"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="EHALDPW"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="32624" checksum="8C73FF8C365B8053" modified="2009-10-13" version="1">MLNTHRLRILAEIHRSGSIAGAARELKLSPSAVSHQLSQLEKEAGVSLVERGAQSLRLTAAGRRLSLRGQEILALLDAAEKDLMAHSRADTGHLCIGYFASAGRRLVPQALSRFARRYPAVELDLVEGQPHELAPAVQQGEIDVLVMFEHALDPWSPPEGVEVRELFNDPQLLVVPTGHPAGRRGQVRLDELAGEQWITSFGTGSPVLSVLERACALEGFVPTIRCRSDHYEVITGLVRAGLGIALIPSLGISDTSGVETTRISGPRLYRKIGVASRPTNPNPVLASFLAYLASTAANLRAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1X0</accession>
    <name>C7Q1X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin-dependent glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6830"/>
    <dbReference type="EnsemblBacteria" id="ACU75671">
        <property type="protein sequence ID" value="ACU75671"/>
        <property type="gene ID" value="Caci_6830"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6830"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026563_1_0_11"/>
    <dbReference type="OMA" id="QYFFAMD"/>
    <dbReference type="OrthoDB" id="151647at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027283">
        <property type="entry name" value="YerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500060">
        <property type="entry name" value="UCP500060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="4">
        <location>
            <begin position="149"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="526" mass="57231" checksum="03F2FA401D445715" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2A6</accession>
    <name>C7Q2A6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiol-disulfide isomerase and thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797367.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8830"/>
    <dbReference type="EnsemblBacteria" id="ACU77643">
        <property type="protein sequence ID" value="ACU77643"/>
        <property type="gene ID" value="Caci_8830"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8830"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110659_1_1_11"/>
    <dbReference type="OMA" id="DWLAQWP"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14910" checksum="E6471AB5A374AE84" modified="2009-10-13" version="1">MEAPLELFDPQRDPHADLASAKAAAAKDGKDILLALGARWCSDCTTFETWTHDPEVAALLAEKYHLVTISVGTARGQRDQNTDIDTNLNHPMAGGIPSLSVLNPEGKIRFDSADGEFSRARKMKPTDLLDFLKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2K6</accession>
    <name>C7Q2K6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ordered locus">Caci_0916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785143.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0916"/>
    <dbReference type="EnsemblBacteria" id="ACU69848">
        <property type="protein sequence ID" value="ACU69848"/>
        <property type="gene ID" value="Caci_0916"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0916"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_0_11"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="61"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="13382" checksum="B07D0F41B6AE0449" modified="2009-10-13" version="1">MAKLSNDELLEAFKEMTLIELSEFVKQFEDVFDVKAAAPVAVAGPAGPAATAEAAVEQDEFDVILEGAGEKKIQVIKVVRELTSLGLKEAKDLVDGAPKPVLEKATKEAAEKAKASLEEAGASVTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M1</accession>
    <name>C7Q2M1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ordered locus">Caci_0931</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785158.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0931"/>
    <dbReference type="EnsemblBacteria" id="ACU69863">
        <property type="protein sequence ID" value="ACU69863"/>
        <property type="gene ID" value="Caci_0931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0931"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044142_4_1_11"/>
    <dbReference type="OMA" id="KRMAGRY"/>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="22615" checksum="FE8975DEE1DB931F" modified="2009-10-13" version="1">MGKQIKGVLGEKLGMTQVWDENNRVVPVTVVKAGPCVVTQIRKQEIDGYEAVQIAYGAVKPTKVTKPEAGHFAKAGVTPRRYTVEIRTTDAAEYSLGQEITAETFTQGQIVDVSGTSKGHGFAGVMKRHNFKGLGAGHGVQRKHRSPGSIGACATPGRVFKGVRMAGRMGSARVTVQNLTVQAVDAEKGLILVKGAIPGPNGGLVLVKTSVKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Q2</accession>
    <name>C7Q2Q2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2885"/>
    <dbReference type="EnsemblBacteria" id="ACU71794">
        <property type="protein sequence ID" value="ACU71794"/>
        <property type="gene ID" value="Caci_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2885"/>
    <dbReference type="HOGENOM" id="CLU_2245069_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="11140" checksum="1BAFFAAC954F9AA1" modified="2009-10-13" version="1">MSRHSEDRLANRAVAMARIAASEKNATVSTATATARFLAVGGAHVIVTRDAAADMTRRWYRAACESCGSLDAVSSDDAIPNRSAQVHAETCRRIPERLWPKGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Q4</accession>
    <name>C7Q2Q4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787089.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2887"/>
    <dbReference type="EnsemblBacteria" id="ACU71796">
        <property type="protein sequence ID" value="ACU71796"/>
        <property type="gene ID" value="Caci_2887"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2887"/>
    <dbReference type="HOGENOM" id="CLU_2768237_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7560" checksum="AA1310FEBD80A92C" modified="2009-10-13" version="1">MQTTSLSAAIPPMSYPLRLRAAARLAWKTLRTGQYLEEAALLNGRRSGLDAGVRITMEEIVQYVPAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Y5</accession>
    <name>C7Q2Y5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787170.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2968"/>
    <dbReference type="EnsemblBacteria" id="ACU71877">
        <property type="protein sequence ID" value="ACU71877"/>
        <property type="gene ID" value="Caci_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2968"/>
    <dbReference type="eggNOG" id="ENOG502ZIDB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1406503_0_0_11"/>
    <dbReference type="OrthoDB" id="2175352at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="21262" checksum="C67F9D0AF69EC76F" modified="2009-10-13" version="1">MNDSADWITNAVRDEAERGYRAYRDSEDGATAEFVAAVPPHQSPEFHLAPLGLYLEWLRGYLAADGAPTHYYDYGYSSRFHVVTGDFTTGGECGAFARAVLVPSGVRHLGGAVGHNDLFFFDGFQASCWVPIYSDAEFLSLPNIVGFIEEQKAAHTTFWAEQERASAASLEAMRGSDLGRHVLKGSGYDQRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q302</accession>
    <name>C7Q302_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2985"/>
    <dbReference type="EnsemblBacteria" id="ACU71894">
        <property type="protein sequence ID" value="ACU71894"/>
        <property type="gene ID" value="Caci_2985"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2985"/>
    <dbReference type="HOGENOM" id="CLU_3045842_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="7001" checksum="C585313A1995EB81" modified="2009-10-13" version="1">MPTRPDPKYPPMGCRWCGIARSQHARQWTEAAGWHAWEKPTNGQIKTRMVERHADSSGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3K6</accession>
    <name>C7Q3K6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/hydrogen exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6938</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795499.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6938"/>
    <dbReference type="EnsemblBacteria" id="ACU75771">
        <property type="protein sequence ID" value="ACU75771"/>
        <property type="gene ID" value="Caci_6938"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6938"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_8_2_11"/>
    <dbReference type="OMA" id="YWKDKFE"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004705">
        <property type="entry name" value="Cation/H_exchanger_CPA1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00831">
        <property type="entry name" value="a_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0050">Antiport</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0915">Sodium</keyword>
    <keyword evidence="5 6" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="7">
        <location>
            <begin position="8"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="510" mass="52353" checksum="7608A8B9C1A1DE9C" modified="2009-10-13" version="1" precursor="true">MVHAVGIVVMLVVLGTAVATFAGRWGIPAPSLLVLAGIVVALVPGVPAIHVAPDVIALVVLPPLLYASAEEISARDLRRVWVPVTVLALGLVLATAAVIASLALALTALSGAMAFVLGAVLASTDPVAVTALGRRLSLPARIQVLVQSESLFNDATSLVLFKVAVAAVVAGGSVSLAGAAGRFLLLAGGGIAVGLALAASVALVRTRTTDPVLDTVIALVAPYAAYLLAESVDVSGVTAVVVAGVAAGSLGHRVSDARTRLHVQTVYAVVVFGLESVVFALIGLELPTLVRDLGPGNSWWPGQAAVLAAALIGIRMLWVWPTTAWAGPTRRYPTWPLVRVVTWSGTRGVMPLAAALSIPLVAADGTPLPGRGLVLVLTTAVVAATLTVQGLSLAGMVKTSGLAVATEHAAAKEQAALAAMNEAAVAYLDELAAVGAVNAVAVERLRQRYAERLDPQTDAGLLDDLAALRRDVLSVQSEELRRLSAQEQISDGMRRRLQADLDRREAGLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Q6</accession>
    <name>C7Q3Q6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797388.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8851"/>
    <dbReference type="EnsemblBacteria" id="ACU77664">
        <property type="protein sequence ID" value="ACU77664"/>
        <property type="gene ID" value="Caci_8851"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8851"/>
    <dbReference type="HOGENOM" id="CLU_2022550_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="11877" checksum="5D5A272E8B863EB8" modified="2009-10-13" version="1">MNAVNASAGEDAVRGLMETAFTAGEPALPDVDDVMATVELLGGHIRHRQRVRTRVAAAMLCLAGFGIVAGIAAVAHSTNTSVTNVVPGGGSGGPPPPPASLTTVGGSAQSSGTSGGTTSVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Z3</accession>
    <name>C7Q3Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797475.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8938"/>
    <dbReference type="EnsemblBacteria" id="ACU77751">
        <property type="protein sequence ID" value="ACU77751"/>
        <property type="gene ID" value="Caci_8938"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8938"/>
    <dbReference type="eggNOG" id="ENOG5032SMY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1132000_0_0_11"/>
    <dbReference type="OMA" id="AGWIRIN"/>
    <dbReference type="OrthoDB" id="1987291at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981404" evidence="2">
        <location>
            <begin position="45"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="24673" checksum="EFC91C97D4712CA3" modified="2009-10-13" version="1" precursor="true">MSNEFLNPRRRTSRYVAVTAVGLAALTGLTYVVASAMSGTHASADSPSTHANAGPTTTAATAVAPAGPGSAAPVTLTPGGQLVGGVSVGYPHTLAGAVSAASEYMTDLGSTLDPDRTAAVMRLVADPSYTDGPAEWAKGTSDARASLGLPTSGLLPSAAAVMLGPAEYQVRDASADQVTVLLLARYTISLPGTGTKSSNAVFPLRMHWAGGDWKVLKPDGATYTSLAAAPGSDQASSLGWQELAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q430</accession>
    <name>C7Q430_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0958"/>
    <dbReference type="EnsemblBacteria" id="ACU69890">
        <property type="protein sequence ID" value="ACU69890"/>
        <property type="gene ID" value="Caci_0958"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0958"/>
    <dbReference type="eggNOG" id="COG4758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102484_4_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="24219" checksum="39AFE7969D96168F" modified="2009-10-13" version="1">MTTQGGASFDPDMRAGDADRERLVEELREQHAAGRLTLEEFDERMTKAYAAKTYGELRTLTRDLPVDLAQLNIQQAQQRTAQPSQRPVEVRRDGSGRMQINIDNQAIQDRINHHVERQTERWQRHQDRHQQRWTQQQERWQQAAARRGGRGGHGLRSAIAFSSWLSLSVLLTGIWLVGNLAGGHDWGNFWPIWPIGITGVLMVARGINRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q469</accession>
    <name>C7Q469_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-alanine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785223.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1001"/>
    <dbReference type="EnsemblBacteria" id="ACU69929">
        <property type="protein sequence ID" value="ACU69929"/>
        <property type="gene ID" value="Caci_1001"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1001"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_23_3_11"/>
    <dbReference type="OMA" id="FEPIGFR"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="18111" checksum="4E977D866413CFBE" modified="2009-10-13" version="1">MAPTLRPFRWWDIETVRRIEEDLFPEDPWSVEMFWSELADVPHSRYYVIAEAEAGSESEIAGYAGLMAQPGSDAGTVEGWIQNIAVARAHQGRGLGAVLLEALLDEALRRKCVEVWLEVRTDNDSAQRLYIRHGFEPAGIRRGYYQPGNHDALIMRKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q476</accession>
    <name>C7Q476_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chaperonin GroEL</fullName>
            <ecNumber evidence="9">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Chaperonin-60</fullName>
            <shortName evidence="9">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">groEL</name>
        <name evidence="9" type="synonym">groL</name>
        <name evidence="12" type="ordered locus">Caci_1008</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Capsule</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785230.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1008"/>
    <dbReference type="EnsemblBacteria" id="ACU69936">
        <property type="protein sequence ID" value="ACU69936"/>
        <property type="gene ID" value="Caci_1008"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1008"/>
    <dbReference type="eggNOG" id="COG0459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_11"/>
    <dbReference type="OMA" id="PYILINQ"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042603">
        <property type="term" value="C:capsule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="477"/>
            <end position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU69936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="56791" checksum="1095D4B22853AC00" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4F9</accession>
    <name>C7Q4F9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787221.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3019"/>
    <dbReference type="EnsemblBacteria" id="ACU71928">
        <property type="protein sequence ID" value="ACU71928"/>
        <property type="gene ID" value="Caci_3019"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3019"/>
    <dbReference type="HOGENOM" id="CLU_2218328_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="106" mass="12259" checksum="49D46653E47CAA6F" modified="2009-10-13" version="1">MPNTEIRRTFTVDQLETLGLPGDNVLARFGEDEHRWYINWQIVFRDPADDTTWAITKSEDKGDNSELPWWYCYDSADKIEAYRVEPREVTITEWVAAESATSEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q526</accession>
    <name>C7Q526_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73974">
        <property type="protein sequence ID" value="ACU73974"/>
        <property type="gene ID" value="Caci_5115"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5115"/>
    <dbReference type="eggNOG" id="ENOG502ZUF7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1575659_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="16917" checksum="3D3754D89BCED7C3" modified="2009-10-13" version="1">MAAAPILNAPTSNAPISNAALARAAQLLGFSVVAVALAVVSWRTVSLNLPDVGQFAGVVGSGFLGGIINPLMKVLNVSGGTVALGDASQVTKKVEVLQDDDAAALRVKRDPMWDIAVVVGAGAIIASALALAINSQHHMNAAAALTALATAFGALFLDTSKITHTPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q556</accession>
    <name>C7Q556_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795553.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6995"/>
    <dbReference type="EnsemblBacteria" id="ACU75825">
        <property type="protein sequence ID" value="ACU75825"/>
        <property type="gene ID" value="Caci_6995"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6995"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_5_11"/>
    <dbReference type="OMA" id="KRWDVIG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="119"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="218"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="41516" checksum="18756992F2B1593E" modified="2009-10-13" version="1">MKPSDHVRAVQAFTRRELIGQEAALDSLADMPLPLYSRFAEAGLANWWVGEEYGGAGLGLQESVRIVSELAYGDAGAAFTLFIPILTTSMVGWYADEQLRKALLSDLVAGHGFASTLGSEHEAGSELARITTTVRRDGDELVLNGLKAFSTDTDFARFTVVVARAEDDPAGYLAVVVPRDAPGLTVDKRWEVIGLRSSATYQVSLKDVRVPASNALRGNGLRLLEVGLNASRILIAATGLGIARRARDLCLDYAKSKQVKGAPLAANAVFAAKLGQMEMQIDVMANQCLTAARDYDAIATRPDAGEEFLRVGTLKSALTAKMFAGQAGWQVVSTASEMFGGLGYTHESIIGKLLRDVRFVSIIEGGDDVLRDLVFTRYVVPVSKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5K7</accession>
    <name>C7Q5K7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9005"/>
    <dbReference type="EnsemblBacteria" id="ACU77818">
        <property type="protein sequence ID" value="ACU77818"/>
        <property type="gene ID" value="Caci_9005"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9005"/>
    <dbReference type="eggNOG" id="ENOG5033NW5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1174889_0_0_11"/>
    <dbReference type="OMA" id="FYAYTKE"/>
    <dbReference type="OrthoDB" id="1292269at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020290">
        <property type="entry name" value="Gp88"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17338">
        <property type="entry name" value="GP88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="29396" checksum="50EB1E17355D814B" modified="2009-10-13" version="1">MSERPTRLLSRANRDLARDGIWSWTIPALAARLPDGTTFRTCRAAGVCSQVCFARSGTYNFPAVKAAHVRNLLFTLEDPEGWEQAMTAELSHPKFAGAHVRIHAAGDFYSAAYARAWLRIIRATPNTSFYAYTKEVMLHDRILEPERPPNAVWIISLGGIYDRYVDLHRHRVCDVFPTETEIEHSGWHSQAESDLLAAYGPAPVAMAANQIPHLQRRQGDRRFSEWQREVDRARGDSTDRPRRRRRIAIAHPVGATDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5N7</accession>
    <name>C7Q5N7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797572.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9035"/>
    <dbReference type="EnsemblBacteria" id="ACU77848">
        <property type="protein sequence ID" value="ACU77848"/>
        <property type="gene ID" value="Caci_9035"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9035"/>
    <dbReference type="eggNOG" id="COG2270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052021_0_0_11"/>
    <dbReference type="OMA" id="MRFCYGA"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="434" mass="45734" checksum="9CDF4282163C849E" modified="2009-10-13" version="1">MSDLRELLRSGLFRRLFATRLIGQFGDGVFQVALAAFVVFSPQKEATAAEVAKAFALLLVPFTVIGPFAGVFLDRWRRRQVLLYANVMRAGIVLIVAAQVLAGHSGILFYASALGVLSCNRFILAGLSAALPQAVDNKRLVVANAVSPTAGTLAATLGGSVGVVVRALVGSGDRANALILVVAAVLYMAGGLVARTMKRDSLGPDQSPGTSTWSELKVVARGLVEGLEHLKERKPAAAALAAITANRFCYGLTTIMVLLLFRNTFNDPQDTNAGLRGFGTAVAVSGFGYFIAAFASPIILRHVRFSTWITVCMIGSGVALAASAGWWRVVPLLIGALVLGFLAQGQKICTDTTVQRNVEDSYRGRVFSLYDMLFNGAFVAAAAVAAATLPASGKSTALLYATVAVYLVTGIAYAWFRAASRSAHHDRSSVSAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5X4</accession>
    <name>C7Q5X4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785365.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1145"/>
    <dbReference type="EnsemblBacteria" id="ACU70071">
        <property type="protein sequence ID" value="ACU70071"/>
        <property type="gene ID" value="Caci_1145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1145"/>
    <dbReference type="eggNOG" id="COG1610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134465_1_0_11"/>
    <dbReference type="OMA" id="MRARDKA"/>
    <dbReference type="OrthoDB" id="2092890at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="13387" checksum="949E7FDA7DDA29BE" modified="2009-10-13" version="1">MTEPSSPASPASPASPSPAPLRDRLRAALPVALKARDRATASTLRATLAAIENAEAVDAGSARAGAIETSAVGIGVAEAARRELTEADVVAIVRAEIAEREHAAEVYEGSGRAEKAAELRSAAAALSEYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Z6</accession>
    <name>C7Q6Z6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795737.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7180"/>
    <dbReference type="EnsemblBacteria" id="ACU76009">
        <property type="protein sequence ID" value="ACU76009"/>
        <property type="gene ID" value="Caci_7180"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7180"/>
    <dbReference type="eggNOG" id="COG3237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182085_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10134" checksum="7D08B8B52F745C15" modified="2009-10-13" version="1">MSVGDKAKHTAEDAKGKVKEAVGKVSGNERMQAEGQADQAEAHAAHAADKAKDTAKNTGQEAKGKVREVAGAVTDDESAEAKGKAEQLAAKAKQHLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C7</accession>
    <name>C7Q7C7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785509.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1290"/>
    <dbReference type="EnsemblBacteria" id="ACU70215">
        <property type="protein sequence ID" value="ACU70215"/>
        <property type="gene ID" value="Caci_1290"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1290"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_11"/>
    <dbReference type="OMA" id="FADIPVM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="117"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36594" checksum="3F7D2470062A8583" modified="2009-10-13" version="1" precursor="true">MISYIIRRLFSAVILLFVISLITFFIFYVFPRLGGQTTESLAEQFVGKTQNPQAIAAVIHRFGFDQSVWVQYGRFIKGIFVGYDYDTGTRMSHCPAPCLGYSFKTNNLVTDSIGQWLPVTISLAVGASVLWLVFGVAVGVASALKKGSVVDRAGMITALVGVSLPVYFVGPLLSLVFVVNWHILPDPGYVHITQDPWGWFTHLLLPWIAVAFGLAALYARLTRVGMLDTMNEDFIRTARAKGLPERTVIFKHALRAALTPIVTIFGMDLGFALGGVVLAEQVFNLPGIGREAVDAVGQSDLPVIMGVTIVASAFIVLANLVVDLLYGVVDPRVRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K3</accession>
    <name>C7Q7K3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787489.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3289"/>
    <dbReference type="EnsemblBacteria" id="ACU72196">
        <property type="protein sequence ID" value="ACU72196"/>
        <property type="gene ID" value="Caci_3289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3289"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058424_0_0_11"/>
    <dbReference type="OMA" id="VGNNWDG"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982994" evidence="1">
        <location>
            <begin position="36"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="409" mass="43265" checksum="C5BF9B0A93849CBF" modified="2009-10-13" version="1" precursor="true">MPRRLQRLTRILAAAGLTAAGLTTTSLTAAPRASAAAGGLRDVLVVGNSQAGTVSVIDGHTFANLGSINVIPDLSQRMLEIYVNPIWLAGYETVRAVEGGDRYVDDATVSPDGRTLYVSRGNLDDVAAFDLTTHAELWHSRLDGFHADHAALSPDGTRYVVSATTAQEAEVFDTATGGVAGTFATGTYPHQNDYSADGKYIYNSSIGITSLPKALEWAKGSFLLTKVDATTLKVVQTWTFPHGIRPNEIAPDGHTFYADQSYLNGFVKYDLNTSQILNTVQMPFASGGTTLSPDNYPQNSAHHGLALNGDGSKLCDVGTIDDYTAIVSTSNLTTAGTVTYPANALPYWGQTSADGQYCFVSLSKLGEVSVIDYATATEVARVPVGAFPQRERISQMAPDAVSALSPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q809</accession>
    <name>C7Q809_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbpA</name>
        <name evidence="3" type="ordered locus">Caci_5317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Bind 1 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5317"/>
    <dbReference type="EnsemblBacteria" id="ACU74176">
        <property type="protein sequence ID" value="ACU74176"/>
        <property type="gene ID" value="Caci_5317"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5317"/>
    <dbReference type="eggNOG" id="ENOG5031DSU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134276_0_0_11"/>
    <dbReference type="OMA" id="VWECRCG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="17929" checksum="666919852905A183" modified="2009-10-13" version="1">MSERALRGTRLGATSYESDAGIDFAPRQDIEYVCPNEHRFVMPFSVEADVPSTWECKVCGATALLVDGAPPEEKAGKPARTHWDMLLERRTMADLEEVLAERLAVLRDGGISRSDVVRPAPARTMAGRAKKSAAAAKASSVKAPAAPAGKPKTTAARSGARKAAAHSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8E8</accession>
    <name>C7Q8E8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795864.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7307"/>
    <dbReference type="EnsemblBacteria" id="ACU76136">
        <property type="protein sequence ID" value="ACU76136"/>
        <property type="gene ID" value="Caci_7307"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7307"/>
    <dbReference type="eggNOG" id="ENOG5032SH2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130935_0_0_11"/>
    <dbReference type="OMA" id="EWASAFT"/>
    <dbReference type="OrthoDB" id="1796008at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18429" checksum="6F25DB294C56F53C" modified="2009-10-13" version="1">MSLTPKNLPESLQPLAAEADRIHESALWSSQGQFEQAKLWRLMNLVLGVPAAVLAAISGGTSLAGHVGAVPGVLGLLAAALGATLTTVNASRRMTQAQASANAYLQLQTEARQFLTIDLEGMSREDAREALRNLTNTRDELNKTADPPGRLAYLRSKKNIGDGGQSYSTDKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H8</accession>
    <name>C7Q8H8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795894.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7339"/>
    <dbReference type="EnsemblBacteria" id="ACU76166">
        <property type="protein sequence ID" value="ACU76166"/>
        <property type="gene ID" value="Caci_7339"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7339"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099824_2_0_11"/>
    <dbReference type="OMA" id="WRIIGTG"/>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="70"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19701" checksum="AC1E00D9C575365D" modified="2009-10-13" version="1">MPHALLLNASYEPLCVVSQRRAVVLILSDKAVTLEGSGDLLHAATWSMPAPSVIRLTRYIRVPNRRAVPLTRRAIFARDGGRCVYCDAPATSIDHVIPRSRGGQHAWDNVVSACRRCNHVKADRPLPDLGWRMRRAPAQPAGSAWRILSSGRQDPRWSPYLEAYGGEPKGLGVDGAFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q990</accession>
    <name>C7Q990_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792139.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3504"/>
    <dbReference type="EnsemblBacteria" id="ACU72410">
        <property type="protein sequence ID" value="ACU72410"/>
        <property type="gene ID" value="Caci_3504"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3504"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_887829_0_0_11"/>
    <dbReference type="OMA" id="NDHGWCE"/>
    <dbReference type="OrthoDB" id="1594780at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="37414" checksum="0D1374B901F3A588" modified="2009-10-13" version="1">MTPAGPARLDRSGALESSEQIDGSEQIERFERVPAEFARYAVDLDAAARLLGLDPRRTAEVARDALPHETDPERGPLFDYVDVMNLALFAGTSRDSIPELALRFLLRFASGPRPSWYEPRHWLVRVRAPRSEEAAMQLLGPDLAAPGVQEVDPRDLPIATTTVEPPGYEVAVRLTGAEATVGDPQVRAIYDDMLEALLSGTVIYQSVSEELRMLHERAWGLGMADCVVVSRLLAQRLRDAGFQARARRGYLLGLVGSDHSWCEYFEDGRWKTLDLVFAFLAGGAGHRRIEASPEFAAACRGGRFNRLLPCDAEEASALILAGDEPAPPWALAGVSAHPWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9K9</accession>
    <name>C7Q9K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5496"/>
    <dbReference type="EnsemblBacteria" id="ACU74355">
        <property type="protein sequence ID" value="ACU74355"/>
        <property type="gene ID" value="Caci_5496"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5496"/>
    <dbReference type="eggNOG" id="COG4933">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135561_0_0_11"/>
    <dbReference type="OMA" id="PQSFRYI"/>
    <dbReference type="OrthoDB" id="1962745at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15809" checksum="A1B60AF9BC931CD1" modified="2009-10-13" version="1">MTDRVLLLSLRPRFAEAILEGSKTVELRRRPIAAGAGTRVVLYSSAPTMAIVGTARLRTVDVAAPETAWKRHRARLGLTKEEFDGYLDGADQAYLLHLTAICELDEPLHLYHLRESGVFQPPQSFRYVAADDPLPLRELAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9N8</accession>
    <name>C7Q9N8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7381</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795935.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7381"/>
    <dbReference type="EnsemblBacteria" id="ACU76207">
        <property type="protein sequence ID" value="ACU76207"/>
        <property type="gene ID" value="Caci_7381"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7381"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="YSLFPWR"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="28384" checksum="061F82FB4575770A" modified="2009-10-13" version="1">MTATIAESTTVDAGASATPAVRLSGVGKTFRGGAPVLDGIDLTVAPGEFVCLLGASGCGKSTLLNLIADLDAPSSGTVEVPSGRAALMFQESALFPWLTAGENIDLALRLRGLSGRRDRRAETERLLDLVRLRGAYDKRPHQLSGGMRQRVALARALAQDSPVLLMDEPFAALDAITRDVLHEELIRLWEATGLAVVFVTHNVREAVRLGQRVVLLSSRPGRVAREWRVDIPQPRRIEDKAVADLSVEITDDLRKEISRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA65</accession>
    <name>C7QA65_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1542"/>
    <dbReference type="EnsemblBacteria" id="ACU70463">
        <property type="protein sequence ID" value="ACU70463"/>
        <property type="gene ID" value="Caci_1542"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1542"/>
    <dbReference type="HOGENOM" id="CLU_211980_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="56" mass="5998" checksum="E81A1928790A450E" modified="2009-10-13" version="1">MSALITAPIARFDCRQHTEPMANHQASNHRAAPCAEPTAHRQISGRSAAADSEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA79</accession>
    <name>C7QA79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1556"/>
    <dbReference type="EnsemblBacteria" id="ACU70477">
        <property type="protein sequence ID" value="ACU70477"/>
        <property type="gene ID" value="Caci_1556"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1556"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OMA" id="THECALA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="162"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="582"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="792" mass="85726" checksum="A206BDD63662DD2C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB1</accession>
    <name>C7QAB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1588"/>
    <dbReference type="EnsemblBacteria" id="ACU70509">
        <property type="protein sequence ID" value="ACU70509"/>
        <property type="gene ID" value="Caci_1588"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1588"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_833610_0_0_11"/>
    <dbReference type="OMA" id="WANAGGR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983066" evidence="2">
        <location>
            <begin position="35"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="36479" checksum="BA5213334FC4E6B8" modified="2009-10-13" version="1" precursor="true">MAGRGRKMWTRTALCAAALATPLAVSGCQSTTNAAGAGGSGGAAAAQAGASSGASSSSSAAAPSSASTSSAPSTSAPSALNATGGTGLTVSEGGSKLLMNGTSVDFGTQVHDPAWSPDGTRLAFIDGGGNLVVANADGSGRTEAAHNPGGQTWSHPTWQTTQADSADNLPPRNNIFFASTAGGATLWEVSTDAHDAQPKQLSLGGYPGQGNTPPSKTANDWPSGGGRYGGAVYEHENGSSSDVYIRDDYLRQQGGLAIKNASEPDYVLVGSSATHEGTPEVVFVRQVGAHKHVFVESIQTSTGGSAAAARDLTPHATTDCTEPAISPDGKTVAFSTSSGVVSVAADGTGNPAFVTHAPGFVAFRPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAK9</accession>
    <name>C7QAK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycoside hydrolase family 48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_3604</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792237.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3604"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH48">
        <property type="family name" value="Glycoside Hydrolase Family 48"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72508">
        <property type="protein sequence ID" value="ACU72508"/>
        <property type="gene ID" value="Caci_3604"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3604"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009014_0_0_11"/>
    <dbReference type="OMA" id="QWFGFQA"/>
    <dbReference type="OrthoDB" id="191946at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.870.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023309">
        <property type="entry name" value="Endo-1-4-beta-glucanase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027390">
        <property type="entry name" value="Endoglucanase_F_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000556">
        <property type="entry name" value="Glyco_hydro_48F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02011">
        <property type="entry name" value="Glyco_hydro_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00844">
        <property type="entry name" value="GLHYDRLASE48"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982681" evidence="7">
        <location>
            <begin position="31"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="8">
        <location>
            <begin position="687"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="8">
        <location>
            <begin position="783"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="9">
        <location>
            <begin position="869"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU72508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="973" mass="101885" checksum="4509F5A203087D9C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAQ2</accession>
    <name>C7QAQ2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable RNA 2'-phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">kptA</name>
        <name evidence="6" type="ordered locus">Caci_5516</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR&gt;P). May function as an ADP-ribosylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the KptA/TPT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5516"/>
    <dbReference type="EnsemblBacteria" id="ACU74375">
        <property type="protein sequence ID" value="ACU74375"/>
        <property type="gene ID" value="Caci_5516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5516"/>
    <dbReference type="eggNOG" id="COG1859">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052998_4_0_11"/>
    <dbReference type="OMA" id="YLYHGTV"/>
    <dbReference type="BRENDA" id="2.7.1.160">
        <property type="organism ID" value="14327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00299">
        <property type="entry name" value="KptA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042081">
        <property type="entry name" value="RNA_2'-PTrans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022928">
        <property type="entry name" value="RNA_2'-PTrans_KptA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684">
        <property type="entry name" value="PTHR12684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19902" checksum="1907A20877992B05" modified="2009-10-13" version="1">MIRLSKRMSSWLRHHPEAIGLEMDGAGWVRVDELLAKAAARGQAFSRAQLEEVVAENTKKRFEFDETETLIRARQGHSIPVELGYATAEPPEVLFHGTAQNTLTLIWRDGLLPMKRHAVHLSPDKETAVKVGSRHGKPAVLAVAAARMHAEGYTFFVTGNGVWLTDAVPAEYLREVPALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAR9</accession>
    <name>C7QAR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conserved TM helix repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794121.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5533"/>
    <dbReference type="EnsemblBacteria" id="ACU74392">
        <property type="protein sequence ID" value="ACU74392"/>
        <property type="gene ID" value="Caci_5533"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5533"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049564_0_1_11"/>
    <dbReference type="OMA" id="FGVWGPN"/>
    <dbReference type="OrthoDB" id="1896788at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29000" checksum="EAFCFCA08013B7F2" modified="2009-10-13" version="1">MGPRLAVSVNWGQGISNAWSSVANIIPKLLAFAVIMVIGWLICKAVAKALDAVLRRAGVERMAERAGAGRVLANSKWDTTAILVKVVYYGLLLVVLQLALGVFGPNPISDMIHSVVAWIPKAIVALIIVVVAMWLANVAREFVTNILSAASYGKVLGWMAWGFIAFFGAIAALAQIGVATFVLGPIMNAVLLTMAGIAIVGVGGGLIQPMRSRWERMLTKAESETTRVQASVQQNALAYQKGRTDARTGQPTDVQRTTQTNTPYGREPGTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW9</accession>
    <name>C7QAW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794171.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74442">
        <property type="protein sequence ID" value="ACU74442"/>
        <property type="gene ID" value="Caci_5583"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5583"/>
    <dbReference type="eggNOG" id="ENOG50333WR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_494087_0_0_11"/>
    <dbReference type="OrthoDB" id="1163358at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="551" mass="59575" checksum="05DD94FAC7CB391B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB83</accession>
    <name>C7QB83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7549"/>
    <dbReference type="EnsemblBacteria" id="ACU76374">
        <property type="protein sequence ID" value="ACU76374"/>
        <property type="gene ID" value="Caci_7549"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7549"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_1_11"/>
    <dbReference type="OMA" id="RVVVYFY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="11"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="17896" checksum="820D5C430D1AF9A2" modified="2009-10-13" version="1">MPSSSLEGVRLNPGDTAPAFTLTDDHGAAVSLADFAGRKVILYAYPAAMTPGCTKQACDFRDNIASFQKEGFAILGLSPDKPEKLAKFRERDALTFPLLSDPDKAVLQEYGAFGEKKLYGKTVVGVIRSTFVLDVDAKGVAKVEVAQYAVKATGHVAKLRRDLGLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB98</accession>
    <name>C7QB98_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, E1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_7565</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H(+) = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10483"/>
            <dbReference type="Rhea" id="RHEA-COMP:10484"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7565"/>
    <dbReference type="EnsemblBacteria" id="ACU76389">
        <property type="protein sequence ID" value="ACU76389"/>
        <property type="gene ID" value="Caci_7565"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7565"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0567">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_11"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00997"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transket_pyr" evidence="13">
        <location>
            <begin position="793"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU76389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1131" mass="123825" checksum="CB5F64C0698888F7" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBB5</accession>
    <name>C7QBB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796131.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7582"/>
    <dbReference type="EnsemblBacteria" id="ACU76406">
        <property type="protein sequence ID" value="ACU76406"/>
        <property type="gene ID" value="Caci_7582"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7582"/>
    <dbReference type="eggNOG" id="COG1752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055284_0_0_11"/>
    <dbReference type="OMA" id="SCAIPGW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="46"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="34970" checksum="BC42BC229B61539A" modified="2009-10-13" version="1" precursor="true">MASTAMRRGLVLGGGGMLGAAWMVGALTVLSEAIGWDPREAEMIVGTSAGSVLAALVGAGATAEDLHEHQLTGRIGQGPLTGVEFDYATAAGGAHPERPKLRLGSGPLLARTARHPRSVPPTAVMAAALPPGRGSLGGVGDLVEGLPRAVDGWSPHKALRIVALDYATGERVTFGSPRAPHTTLAEAVTASCAIPGWFAPIIIDGRRYVDGGMWSATNVDVAAKQGFEEIGEPPLDELYVLAPMAVRGFNGPPHSVMERVARRYRRGVTRRMLVEAQRVRADGTKVIVFCPTADDFEAIGLNVMDVGRRPHVLETAMRTTREQIEAQRTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBL3</accession>
    <name>C7QBL3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide 4</fullName>
            <ecNumber evidence="10">7.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome aa3 subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cytochrome c oxidase polypeptide IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_1669</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Part of cytochrome c oxidase, its function is unknown.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Associates with subunits I, II and III to form cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cytochrome c oxidase bacterial subunit CtaF family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785884.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1669"/>
    <dbReference type="EnsemblBacteria" id="ACU70590">
        <property type="protein sequence ID" value="ACU70590"/>
        <property type="gene ID" value="Caci_1669"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1669"/>
    <dbReference type="eggNOG" id="ENOG5032TTI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145919_0_0_11"/>
    <dbReference type="OMA" id="GTYFRFV"/>
    <dbReference type="OrthoDB" id="1844113at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021050">
        <property type="entry name" value="Cyt_c_oxidase_su4_actinobac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12270">
        <property type="entry name" value="Cyt_c_ox_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017385">
        <property type="entry name" value="CtaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="15806" checksum="B7907942B0730A5A" modified="2009-10-13" version="1">MKVEAKLFGFVAIFLMIDIPVYWFLSKDTVGTTALSMAFGLCSLVWFYLYFTAIRIGPRPEDRDDAEIAEMAGELGFFAPHSWWPLYTAGSAALAFMGIIFGWWLLLVAFPFGAYSVIGLVFEYYRRENNRYGEVGAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY0</accession>
    <name>C7QBY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lantibiotic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792328.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3697"/>
    <dbReference type="EnsemblBacteria" id="ACU72599">
        <property type="protein sequence ID" value="ACU72599"/>
        <property type="gene ID" value="Caci_3697"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3697"/>
    <dbReference type="eggNOG" id="ENOG502ZMHZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_211085_0_0_11"/>
    <dbReference type="OMA" id="TFAISDY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023895">
        <property type="entry name" value="Thiopep_bacteriocin_prcur"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03892">
        <property type="entry name" value="thiopep_precurs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="65" mass="6723" checksum="5DEA5CAFA890E9F2" modified="2009-10-13" version="1">MQIHTTETLEDTSVTALAAEILALESETFEITDYSDASEVMLGSSTSCSSTSTCSSTTSTTSCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCB6</accession>
    <name>C7QCB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-disulfide isomerase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794293.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5706"/>
    <dbReference type="EnsemblBacteria" id="ACU74564">
        <property type="protein sequence ID" value="ACU74564"/>
        <property type="gene ID" value="Caci_5706"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5706"/>
    <dbReference type="eggNOG" id="COG1651">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_47_3_11"/>
    <dbReference type="OMA" id="GTHDSWV"/>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="80"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="33857" checksum="D5E61A063113F646" modified="2009-10-13" version="1">MSQANRVGKQNARERVLAEKIARQRAERRRKQLTIGGVVVLVVAVAGGVGIAVSAAKHNSTPYAAPAAAVIDPQAKSSKATGIHIGSNDAPVKMNVFEDFRCPVCQEVETAVEPTYRQYVEAGKLQITYHPARVIDSHDNGSGSLNGANAAACAQDQGDFLQLHDLLYANQPNEQTDPWADRSAVLKIADEIPALKSSPGFQSCVTGGTHNGWVQSNADNFNKLGLPGTPTVFIDGQQLSFTQTSADAVLQYFQGQLDAAFKKDGGKAGTPTTLPTAPTSAPSSGASSSGASSSAGAPSSSGAPSSSGSPSGTPTGTSSSTGSTPTSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCC2</accession>
    <name>C7QCC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794299.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5712"/>
    <dbReference type="EnsemblBacteria" id="ACU74570">
        <property type="protein sequence ID" value="ACU74570"/>
        <property type="gene ID" value="Caci_5712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5712"/>
    <dbReference type="HOGENOM" id="CLU_172614_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="6533" checksum="4C219403547DF917" modified="2009-10-13" version="1">MSSSHDEDHGSTPAAWTAVFLCIIGFLIGGAGLVTAVPALAVVGGAIAVLSPIVGKAMSAMGLGAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCI1</accession>
    <name>C7QCI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796169.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7620"/>
    <dbReference type="EnsemblBacteria" id="ACU76444">
        <property type="protein sequence ID" value="ACU76444"/>
        <property type="gene ID" value="Caci_7620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7620"/>
    <dbReference type="eggNOG" id="COG0748">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115408_0_0_11"/>
    <dbReference type="OMA" id="PHGATRW"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="38"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="18764" checksum="C42BCDFF9621C66E" modified="2009-10-13" version="1">MSELKPLRAKNLALPKYGLDQLVWDEVEAAVAAAVAGPGRSWFLSTLNPDGSPHTTAFGHTWLDGAIHFTTGPETRKTRNLLADPRCTVAAPIEDFDVTFDGEARRATDPAVVAAVAEMYAAVGWPCQAEGDVITAPFSAPSAGPGPWQVYRIELLTVVALKSTGDGGVTKWWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDN5</accession>
    <name>C7QDN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein TetR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5801"/>
    <dbReference type="EnsemblBacteria" id="ACU74659">
        <property type="protein sequence ID" value="ACU74659"/>
        <property type="gene ID" value="Caci_5801"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5801"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_11"/>
    <dbReference type="OMA" id="HACHEAL"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="20703" checksum="9C0D14FC7D9170E6" modified="2009-10-13" version="1">MDSPARRPLRADAARNVQALVAAAKELFDEQGSDVALDEIARRAGVGNATLYRNFPTRADLIVAVYADEVAELCLRGAALRETEAAGEALFAWLDSFVVHVATKRALALAGTEHNTERRTQLFDTWHEAMRKVAGDLYDRAREAEAVSPDVSAEELLALTSAAAIASNGPEHARRLLRMMRYGFARHSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDV1</accession>
    <name>C7QDV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase LigD, polymerase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5867"/>
    <dbReference type="EnsemblBacteria" id="ACU74725">
        <property type="protein sequence ID" value="ACU74725"/>
        <property type="gene ID" value="Caci_5867"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5867"/>
    <dbReference type="eggNOG" id="COG3285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008325_1_0_11"/>
    <dbReference type="OMA" id="TTAWWKE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014145">
        <property type="entry name" value="LigD_pol_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02778">
        <property type="entry name" value="ligD_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="357" mass="39206" checksum="DBDE93135619BB85" modified="2009-10-13" version="1">MCPGVRMSVAGRSLPTMGSAEAHVEAGGRSVRISSPDKLLFPDADVTKLGLATYYAAVADGLFRGLANRPVALNRFPDGLGGKSFFTKSAPKGLPDWASTAHVTFPSGRTGDEVCVTEPATVLWTVQMGTLELHAWPVREADTDHPDELRIDLDPQPGTGFAEAVEVAREALALFEELGIRPFVKTSGGRGLHLLVRIEPRWTFVEARRAVIALARELERRRPEMVTTSWWKEERGERIFIDFNQMARDRMTVAPYSTRARPDAPVSMPVRWADLADVAPGDFTVKTVPDLFAKNGDANAEIDDTAHSLDALLEMAERDEKDHGLGDMPYPPDFPKMPGEPKRVQPSKARHDQEGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE28</accession>
    <name>C7QE28_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7792</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796341.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7792"/>
    <dbReference type="EnsemblBacteria" id="ACU76616">
        <property type="protein sequence ID" value="ACU76616"/>
        <property type="gene ID" value="Caci_7792"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7792"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_0_11"/>
    <dbReference type="OMA" id="NMAYFTP"/>
    <dbReference type="OrthoDB" id="1413173at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="11"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="126"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="384" mass="40164" checksum="ED65202A90D5E1B9" modified="2009-10-13" version="1">MSIAVEHGITEDAIHKALSKVQDPEIHRSITELDMVKEVHVAADGTVKVAIFLTVAGCPMKDRLTNDIKSEVGTIAGVSAVEVELDVMSSEQREALKTKLRGGQVDREIPFAQPGSLTRVYAIASGKGGVGKSSVTVNLAAALVAKGLKVGVVDADIYGHSIPRMLGVTEPPTPIDDMILAPTAPSGVKVISIGMFTPGNSPVVWRGPMLHRAIQQFLGDVYWGDLDVLLLDLPPGTGDIAISVAQLVPNAEILVVTTPQQAAAEVAERAGTIAVQTRQRITGVIENMSWMPCPHCGEQVDVFGSGGGETVAEALTRATGTKVPVLGQIPIDVRLREGGDNGQPLTASDPDSPAAQVLIGIADKIATRSRGLVGMSLGVSPVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI4</accession>
    <name>C7QEI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mandelate racemase/muconate lactonizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786168.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1955"/>
    <dbReference type="EnsemblBacteria" id="ACU70875">
        <property type="protein sequence ID" value="ACU70875"/>
        <property type="gene ID" value="Caci_1955"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1955"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_9_0_11"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd03323">
        <property type="entry name" value="D-glucarate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034598">
        <property type="entry name" value="GlucD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="3">
        <location>
            <begin position="171"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR634598-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="45520" checksum="836C0EBBACE5BF78" modified="2009-10-13" version="1">MTDLKIVDVVITPVALKDPPLLNSSGVHEPFALRSIVEVQTDAGIVGISEAYGDDATLALLHQAATAVVGTDVFDLNELSRRVASAVGGSAASSPTELIGTASHDKTVAQATAAFEVACYDAQGKATGRRVVDLLGGAVRERVDFSAYLFYKWAEHPGDFDVDSWGEALDPDGIVKQARRMVDRYGFGSLKLKGGVFAPEEEIEAVKALRREFPDRPVRIDPNANWSVQTSHRVAAALEGELEYLEDPTPGIPGMAEVAAKTSLPLATNMCVTSFAEIPESVRLGAVQVILSDHHFWGGFRATQNLAALCQTFGLGLSMHSNTHLGVSLAAMAHIAAATPNLTYALDTHTPWKSEEEDVVLGGGLTFTDGAVTLPSGPGLGVELDRDALAKLHEQYLTCGIRRRDDVGWMRQVHPEWTGKRPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEX0</accession>
    <name>C7QEX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792619.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4022"/>
    <dbReference type="EnsemblBacteria" id="ACU72890">
        <property type="protein sequence ID" value="ACU72890"/>
        <property type="gene ID" value="Caci_4022"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4022"/>
    <dbReference type="HOGENOM" id="CLU_2536415_0_0_11"/>
    <dbReference type="OrthoDB" id="60598at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="9157" checksum="6B2B9D18254858F3" modified="2009-10-13" version="1">MTPSTEPAVRQFIKRCNGAEPGELLDEVHAEAALRRAADNGFEIFGSLVSGSAAWRNEVQDLTFSLTEATEADAQRRQHKWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFA9</accession>
    <name>C7QFA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7863"/>
    <dbReference type="EnsemblBacteria" id="ACU76686">
        <property type="protein sequence ID" value="ACU76686"/>
        <property type="gene ID" value="Caci_7863"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7863"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_0_1_11"/>
    <dbReference type="OMA" id="SDGFPRD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="14"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14875" checksum="703169EA700AFB67" modified="2009-10-13" version="1">MNDPNLTQAARNLNWLITNFVDRVPGVAHTVVVSSDGLLLAVSDGFPRDRADQLAAVASGLSSLTQGAARIFEGGAVTQTVVEMVRGFLFVMAISDGSALAVLASSDCDMGLIGYEMALLVERAGDVLTPALRAELQSSLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFB2</accession>
    <name>C7QFB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796414.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7866"/>
    <dbReference type="EnsemblBacteria" id="ACU76689">
        <property type="protein sequence ID" value="ACU76689"/>
        <property type="gene ID" value="Caci_7866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7866"/>
    <dbReference type="HOGENOM" id="CLU_2286411_0_0_11"/>
    <dbReference type="OrthoDB" id="1789144at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="101" mass="10882" checksum="DAECEF480EFC5BA4" modified="2009-10-13" version="1">MSGTIALTRRSGFQLRPRPYRVWIDGVAVGRLPQNGAAEFAVDSGVHLVELSLDGMYSKKVSVEVREGGTRRLHCGAHGPLAFSAFGLLLPGLAIRLTLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFP2</accession>
    <name>C7QFP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0026"/>
    <dbReference type="EnsemblBacteria" id="ACU68981">
        <property type="protein sequence ID" value="ACU68981"/>
        <property type="gene ID" value="Caci_0026"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0026"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_0_11"/>
    <dbReference type="OMA" id="CPSRGTL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="35"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU68981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16684" checksum="9B0201194AAA3C4C" modified="2009-10-13" version="1">MSTRVVTPGVVTPEAEERALGMAYDVVYDVLQAPCPSRQALEHVTGRWGALIMMALREGPVRFNELRRRVDGVSEKMLSQGLQALERDGFVAREVQSTMPPKVEYQLTPLGTQTSDRLADLVEFLEGRMPEVEAAQARHDEAASAAASVSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR4</accession>
    <name>C7QFR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784298.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0048"/>
    <dbReference type="EnsemblBacteria" id="ACU69003">
        <property type="protein sequence ID" value="ACU69003"/>
        <property type="gene ID" value="Caci_0048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0048"/>
    <dbReference type="HOGENOM" id="CLU_116311_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13369" checksum="5D261D881A8E25E9" modified="2009-10-13" version="1" precursor="true">MRRRRPRDAGYATVEAALAIPSLVLFTVALAGILTGLATQIRCVDAARLGARAAARGEPAAQIQGAVTQAAPGSSIHITTENGLIHVSVAAPVAAMPLLRAFTVHAEAYEADEATLEGGEEPHAAAEPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU4</accession>
    <name>C7QFU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2001"/>
    <dbReference type="EnsemblBacteria" id="ACU70921">
        <property type="protein sequence ID" value="ACU70921"/>
        <property type="gene ID" value="Caci_2001"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2001"/>
    <dbReference type="eggNOG" id="COG3511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_436606_0_0_11"/>
    <dbReference type="OMA" id="YMENEDY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042578">
        <property type="term" value="F:phosphoric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044003">
        <property type="term" value="P:modulation by symbiont of host process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981611" evidence="2">
        <location>
            <begin position="42"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="626" mass="64715" checksum="6F72812B51C98E18" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA3</accession>
    <name>C7QGA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792677.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4083"/>
    <dbReference type="EnsemblBacteria" id="ACU72948">
        <property type="protein sequence ID" value="ACU72948"/>
        <property type="gene ID" value="Caci_4083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4083"/>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_415543_0_0_11"/>
    <dbReference type="OMA" id="VMTHETL"/>
    <dbReference type="OrthoDB" id="697274at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="685" mass="68473" checksum="37917A771BEADC0B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGP0</accession>
    <name>C7QGP0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucokinase</fullName>
            <ecNumber evidence="2">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794649.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6063"/>
    <dbReference type="EnsemblBacteria" id="ACU74920">
        <property type="protein sequence ID" value="ACU74920"/>
        <property type="gene ID" value="Caci_6063"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6063"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_0_11"/>
    <dbReference type="OMA" id="APNIDWR"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004654">
        <property type="entry name" value="ROK_glcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00744">
        <property type="entry name" value="ROK_glcA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="31761" checksum="BC712D7275BF386A" modified="2009-10-13" version="1">MTLTIGVDIGGTKILAGVVDEKGKILDSVKVSTPENSDQTADAIAEAVRKVRADHEIGAVGLGAAGFIDADRATVLFAPNVSWVNEPLKNRIEERIGLPVVVENDANAAAWGEAKFGAAAGHDDVVVITVGTGIGGGLILGGSLYRGRFGIGGEPGHYRVVPDGRPCGCGNRGCFEQYASGNALVRAARERAAAAPGRAKELLALGDGTVEGIQGAHVTEAARGGDTIALAAFNEIADWLGQGMSDIAALLDPSAFVLAGGVSEAGDLLRAPAAEAYRRKLAGKGHRPYAQILTATLGPDAGLIGAADLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV2</accession>
    <name>C7QGV2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="6">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="6">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">folD</name>
        <name evidence="9" type="ordered locus">Caci_7979</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="6"/>
    <dbReference type="EC" id="3.5.4.9" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796527.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7979"/>
    <dbReference type="EnsemblBacteria" id="ACU76802">
        <property type="protein sequence ID" value="ACU76802"/>
        <property type="gene ID" value="Caci_7979"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7979"/>
    <dbReference type="eggNOG" id="COG0190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034045_2_1_11"/>
    <dbReference type="OMA" id="HIVGRPM"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="7">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="8">
        <location>
            <begin position="123"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="29005" checksum="A26085C2A41809D3" modified="2009-10-13" version="1">MTAQILDGKATAATIKGELSARVEALKARDIVPGLATLLVGDDPASASYVRSKHRDCAQVGIASIQRQLPATASQAQVAEAVAELNEDPACTGYIVQLPLPKGIDENAILELVDPNKDADGLHPTNLGRLVLGAPAPLPCTPLGIVELLRRHDVAIAGAEVVIVGRGITVGRPLGLLLTRRSENATVTLCHTGTRDLAFHTLKADIVVAAAGVPNLITADLVKPGAAVLDVGVSRGEGGLAGDVADDVRDVAGWVSPNPGGVGPMTRAMLLNNVVEIAERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGZ9</accession>
    <name>C7QGZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dak phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796574.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8026"/>
    <dbReference type="EnsemblBacteria" id="ACU76849">
        <property type="protein sequence ID" value="ACU76849"/>
        <property type="gene ID" value="Caci_8026"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8026"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017496_0_1_11"/>
    <dbReference type="OMA" id="TRTIPQG"/>
    <dbReference type="OrthoDB" id="1554133at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13684">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="24"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="601" mass="61041" checksum="04F315F1494BF838" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHE8</accession>
    <name>C7QHE8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784382.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0132"/>
    <dbReference type="EnsemblBacteria" id="ACU69087">
        <property type="protein sequence ID" value="ACU69087"/>
        <property type="gene ID" value="Caci_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0132"/>
    <dbReference type="eggNOG" id="COG4289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028269_0_0_11"/>
    <dbReference type="OMA" id="YYNGWAM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="PTHR35339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014753">
        <property type="entry name" value="UCP014753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="632" mass="68869" checksum="33B43EA0CD5DADF1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR0</accession>
    <name>C7QHR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2166"/>
    <dbReference type="EnsemblBacteria" id="ACU71085">
        <property type="protein sequence ID" value="ACU71085"/>
        <property type="gene ID" value="Caci_2166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2166"/>
    <dbReference type="HOGENOM" id="CLU_3395715_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="31" mass="3271" checksum="52E82948C8FBF4FE" modified="2009-10-13" version="1" precursor="true">MNGTVFGIILIVLAAAGGAALWVDTIRKRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE6</accession>
    <name>C7QIE6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6169</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6169"/>
    <dbReference type="EnsemblBacteria" id="ACU75023">
        <property type="protein sequence ID" value="ACU75023"/>
        <property type="gene ID" value="Caci_6169"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6169"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_11"/>
    <dbReference type="OMA" id="PWVHRGE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="310"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="596" mass="59004" checksum="CBD4B50FFB560261" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG6</accession>
    <name>C7QIG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6189"/>
    <dbReference type="EnsemblBacteria" id="ACU75043">
        <property type="protein sequence ID" value="ACU75043"/>
        <property type="gene ID" value="Caci_6189"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6189"/>
    <dbReference type="HOGENOM" id="CLU_2970982_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983162" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="58" mass="6249" checksum="F1D61AC222864F89" modified="2009-10-13" version="1" precursor="true">MRIYLASKRRLIVSAVVLAVGLALLIPAAAMAGVRADRQHSVGDGSDRGDQVRILRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ9</accession>
    <name>C7QIZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784436.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0186"/>
    <dbReference type="EnsemblBacteria" id="ACU69141">
        <property type="protein sequence ID" value="ACU69141"/>
        <property type="gene ID" value="Caci_0186"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0186"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="SETHAPD"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="16971" checksum="78D76ECAC58CB53D" modified="2009-10-13" version="1">MEARLNTFATPTGAKFGKYLIAAGRVLREAGVPVATLHLVEIRASQINGCGFCLDMHTKDATAAGETAERLNMVAAWREAACYTEAERAALELTEAGTRLADGTGVADEVWDAAAKHFDEDQLATLVAQIALINAFNRGNVMVKQPAGDYVPGQFDDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJB7</accession>
    <name>C7QJB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784554.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0306"/>
    <dbReference type="EnsemblBacteria" id="ACU69259">
        <property type="protein sequence ID" value="ACU69259"/>
        <property type="gene ID" value="Caci_0306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0306"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056335_0_0_11"/>
    <dbReference type="OMA" id="DEPLAYC"/>
    <dbReference type="OrthoDB" id="1707650at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="128"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="33475" checksum="E0E4814F310C9BDA" modified="2009-10-13" version="1" precursor="true">MFADAWPLAVLAILLAWPVPVFLARAAWPRRHARAAIALWQAVGVAGGLALIGAPLAVGVAPLDGHLRTGLVELWRDAFHLRVPAALGLAQEIALALAAVLTVRLVGVTLLSAWRIERDLRRQRDAVDLAAEHADRDLRVLEHAAPAAYCLPGTRPRIVITEGTIAALAPDELEAVLAHERAHARWRHELVVQPFVAWESALPLPPARRATASVTALVEMLADDHAARSVGRPALARALVAIGGTAGPVPNQRTDGAPGSGSDPNPVRATPTLDRVQRLVRRPKATSLAERLIGPAAWLAAVLLVAGPTWYVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJC4</accession>
    <name>C7QJC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2228"/>
    <dbReference type="EnsemblBacteria" id="ACU71147">
        <property type="protein sequence ID" value="ACU71147"/>
        <property type="gene ID" value="Caci_2228"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2228"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_3_2_11"/>
    <dbReference type="OMA" id="NAVLYFR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="37496" checksum="B1B03A032C8E78AC" modified="2009-10-13" version="1" precursor="true">MITAIVSAIVAAAAAGAVGFGASLRTVKQYERGIVFRFGKVLDSVRQPGLTRIIPGVDRMRTVNMQVVTMPVPAQEGITRDNVTVRVDAVVYFRVVDPARALIYVQDYKYAVSLVAQTSLRSIIGKSLLDDLLSNREPLNQGMELMLETPATGWGVEIDRVEIKDVALPESMKRSMARQAEADRERRARIITADGEFQASSKLADAARIMSETPSALQLRLLQTIVEVAAEKNSTLVLPFPVELLRFLESAGGGAPTQALKAAQKAVDALTTDKAEAVETASETIAIEGGEADAAAAPTADKIPEASPLPDLAPAADAIARPLTEPLIEAPHWRDAAEPSDDSDTSKPSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM2</accession>
    <name>C7QJM2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2327"/>
    <dbReference type="EnsemblBacteria" id="ACU71245">
        <property type="protein sequence ID" value="ACU71245"/>
        <property type="gene ID" value="Caci_2327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2327"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037000_0_0_11"/>
    <dbReference type="OMA" id="CKWEKGD"/>
    <dbReference type="OrthoDB" id="1759737at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="502" mass="54635" checksum="74FF35C32EF94090" modified="2009-10-13" version="1">MQVDSGSSPGKKPAGNTALKALRLSRHWTQAEFAAEFEKASRALGKVLSLSVRQVRRWESEDPPCPLPAYQRVLEEVFGVSVAQMGFQVGWSVPWAPRPEPSQPPTAATGRAAPEAELEEDGGAGGTQHGRMAGLCRTRPADRSGGHDPVKRREFVTSAAAALTVAGAAGENTAYGAEAPERMPAAADPAGRAVPFDRQMVDGYEFITSQQRSLYYTVPPARMYSPAVAHAQLGAALLSGTGPQTQRSRLAGSLAEASLLAARLAFFDLKKAEPARMHYRNALVAAREADDHQLGSAILAHLAFIPAWDGKAGESRDLMRAAYAHAARGVSAVQRSWLHAVDAEIEARLGDNKRAVDLIGRAEEALSDADRSAVPDPEWLDYFDATRLNGFKGFCHINGGSPELAQEALLCSLMALKPNEAKQRTIVLADMADIHVRTKEIEQACVTLERALVNLDKHWYGIGWDRIYNVRRKMDNFEDTRSVRELDMRMNSSWGATMRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJT4</accession>
    <name>C7QJT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Taurine dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.11.17" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792901.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4308"/>
    <dbReference type="EnsemblBacteria" id="ACU73172">
        <property type="protein sequence ID" value="ACU73172"/>
        <property type="gene ID" value="Caci_4308"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4308"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_2_1_11"/>
    <dbReference type="OMA" id="FVDAYPK"/>
    <dbReference type="OrthoDB" id="1742732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000908">
        <property type="term" value="F:taurine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="3">
        <location>
            <begin position="10"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="33246" checksum="F0BAF7E1F498424C" modified="2009-10-13" version="1">MTTTPTDFDIRRIGGRIGAEITGVDLAGNLDEGILKEVKAALLEHKALVFRNQNLDDEGQLRFASQFGPLTSAHPTVPGIAEQPQILPVDSERGAANVWHTDVTFVQSPPKASTLRGIVIPPYGGNTLIANTAAAYRDLPKPLRDLADTLWAVHTNDYDYAGPKGDDEKRQQYRDVFVSTKYRTAHPVVRVHPETGERGLFIGAFAQTIEGLSTTESKDVLRLLQAYVNRPENVLRVQWNPGDVVIFDNRITQHYAPDDYDTLPRRLNRVTIAGDVPVGIDGSSSRILEGDEAAHYTPATAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJZ8</accession>
    <name>C7QJZ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792965.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73236">
        <property type="protein sequence ID" value="ACU73236"/>
        <property type="gene ID" value="Caci_4372"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4372"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_23_1_11"/>
    <dbReference type="OMA" id="CMFTRAL"/>
    <dbReference type="OrthoDB" id="1826886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20615" checksum="7EED936E68BC79C4" modified="2009-10-13" version="1">MPNTAPSPKDRLLDTARRLFYTEGIHTVPVDRLVTEANVTRATFYRHFPAKENLVEAYLRATDDDLRAAVAEALDQGTAQESAAALLELIGQVTCSAGFRGCHFINASAEYPDPEDPIRVAVADHRAWFQDTVTRLAERAGHPDPEYAGRVLVLLHDGALSAAELDDPQQVRETVIRAGRELLRLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB2</accession>
    <name>C7QKB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794915.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6332"/>
    <dbReference type="EnsemblBacteria" id="ACU75186">
        <property type="protein sequence ID" value="ACU75186"/>
        <property type="gene ID" value="Caci_6332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6332"/>
    <dbReference type="eggNOG" id="COG1168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_15_2_11"/>
    <dbReference type="OrthoDB" id="1462898at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="97"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="394" mass="41928" checksum="B70EB3A44A8A0706" modified="2009-10-13" version="1">MSDASAVSADPDWLRSKPGLKWATAAPDVLPAWVAEMDFAVPPPVRQVLTDFAAIGDLGYPAWMEGSGTPLREAFRDRMTARYDWSPDPAHVREFTDLNQALQAVLHVATEPGDAVAMHVPGYPTFLRAVPKMGRRLIPVPLHRDEDGWSSDADCLDAAVTASGARTLILVNPNNPVGRVLTRSELSAIATVAEARDLLVISDEIHADLTYAPAVHIPFASLSADAQARTVTMTSASKAFNIAGACCAVAYVGSERVRDGLDRLPPDLLGRLGAVGVAATLAAWREGDPWLAAVLETLSANRDVLGAALPKDIGYVPPEATCLAWLDCRSLGLSDPADFFLRKAGVDLISGSSFGTFGEGFVRLNFGTTPAILTEICARMTEAVTSLGQRPCEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKI4</accession>
    <name>C7QKI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796808.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8260"/>
    <dbReference type="EnsemblBacteria" id="ACU77083">
        <property type="protein sequence ID" value="ACU77083"/>
        <property type="gene ID" value="Caci_8260"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8260"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048989_0_0_11"/>
    <dbReference type="OMA" id="RYDDWSW"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="32718" checksum="77F602D33829D208" modified="2009-10-13" version="1">MNAADDAADQPAPIRVRAAGCVVWRPGPAGPEVALIHRPRYDDWSFPKGKLDEGEGYVQAAIREVREETGYPVVLGRRLPTQVYDVSFGGPARTKRVKYWAAQAAVDADFQPNSEVDRLEWLPLDGATARLTRQTDRDLLQAFAAAPVDTVPVLLLRHAEAIPRKRWDGPELERPLTGRGRNDAEALVPVLAAYGEATLVASPFARCVATLTPTARAAGAELTLEPALGEGSDPDAGRGWLRGVLKAGRTTVACTHRPVLPELLAESPLAQAMHSGRRALAPAEAWVLHARDGHVVAVDRLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL2</accession>
    <name>C7QKL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall-binding domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8288"/>
    <dbReference type="EnsemblBacteria" id="ACU77111">
        <property type="protein sequence ID" value="ACU77111"/>
        <property type="gene ID" value="Caci_8288"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8288"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023724_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015020">
        <property type="entry name" value="DUF1906"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08924">
        <property type="entry name" value="DUF1906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981773" evidence="1">
        <location>
            <begin position="32"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="627" mass="63819" checksum="BD143B03801366FC" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKP7</accession>
    <name>C7QKP7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5709 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796871.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8323"/>
    <dbReference type="EnsemblBacteria" id="ACU77146">
        <property type="protein sequence ID" value="ACU77146"/>
        <property type="gene ID" value="Caci_8323"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8323"/>
    <dbReference type="eggNOG" id="ENOG5032UXC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109389_0_0_11"/>
    <dbReference type="OMA" id="RPWAVEH"/>
    <dbReference type="OrthoDB" id="1593638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043763">
        <property type="entry name" value="DUF5709"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18970">
        <property type="entry name" value="DUF5709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5709" evidence="2">
        <location>
            <begin position="92"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16091" checksum="25CF750D56214009" modified="2009-10-13" version="1">MSSGFADDVYLPQPDPDAQDPLEQLDGADTLISGPDELDTGYSPPERPRALRDPETMDERLAEEVPDDEDLPEDWDGLGDYAGGDGELLGDQVGGRRSGRLMAPDEGSHSGGNADLSAQDVGIDGGAASAEEAAMHVVDDEELDEEYDDAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ1</accession>
    <name>C7QKQ1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="9" type="ordered locus">Caci_8327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8327"/>
    <dbReference type="EnsemblBacteria" id="ACU77150">
        <property type="protein sequence ID" value="ACU77150"/>
        <property type="gene ID" value="Caci_8327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8327"/>
    <dbReference type="eggNOG" id="COG2344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061534_0_1_11"/>
    <dbReference type="OMA" id="HEQRKAG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="8">
        <location>
            <begin position="104"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="236"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="115"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="28614" checksum="269E19870EB2B3AA" modified="2009-10-13" version="1">MASTSSNASGGTGPDSRSGNGSSLRSHRQGIPEATVARLPVYLRALISMQERGIITVSSEELAASAGVNSAKLRKDFSYLGSYGTRGVGYEVSFLVYQISRELGLTQDWAVAIIGIGNLGHALANYGGFASRGFRVAALFDADPALTGSVVAGVRVRHADELESAIRGLGISIFVISTPAPAAQPVADRLVAAGITSILNFAPVVLNVPEGVDVRKVDLSIELQILAFHEQRKGGHALPQAGADPAAPDGGGKTAGGPAAASPDRSELDSSLIDTGIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ4</accession>
    <name>C7QKQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8330"/>
    <dbReference type="EnsemblBacteria" id="ACU77153">
        <property type="protein sequence ID" value="ACU77153"/>
        <property type="gene ID" value="Caci_8330"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8330"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_0_11"/>
    <dbReference type="OMA" id="AETADIM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014298">
        <property type="entry name" value="RNA_pol_sigma-X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02952">
        <property type="entry name" value="Sig70_famx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="123"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="221"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30617" checksum="BA74F3881E0B7A40" modified="2009-10-13" version="1">MYRDNFGLNGYSAKVGGDPFAGTGSLSTQVLSTHVPMPSSASLLDRQERGLLMLREAIRVVAGDGTGRGAHAAGTRSGGARHGGGSGTADRSGGPVAGDGESEAMVHLVRQAQEGSADAFGELYRIYCDTVFRYIYYRVSTRALAEDLTSETFVRALRRITTFSWQGRDFGAWLVTIARNLVADHFKSSRHRMEVSTGEMLDSNEVEASPEDSVLEHLSNEALLHAVHRLNDQQRECVTLRFLQGLSVAETADIMGKNEGAIKTLQYRAVRTLARLLPAEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ2</accession>
    <name>C7PVJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784643.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0396"/>
    <dbReference type="EnsemblBacteria" id="ACU69348">
        <property type="protein sequence ID" value="ACU69348"/>
        <property type="gene ID" value="Caci_0396"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0396"/>
    <dbReference type="eggNOG" id="COG3193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103773_2_2_11"/>
    <dbReference type="OMA" id="NNWAVTI"/>
    <dbReference type="OrthoDB" id="2066293at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="13607" checksum="C51D5A666343B8CF" modified="2009-10-13" version="1">MSISLVQAEAVVAAARVGADERGVAVAFAVVDAGGNLVAFARGDGANLITVDTAIGKAFTAISIGADSINLTAAIQPGGPLFGTGLVLAGARSFVPYGGGVLIRVDGRVVGALGIAGAASSEVDHEIAAAAAVQVPVRVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVK4</accession>
    <name>C7PVK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0408</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0408"/>
    <dbReference type="EnsemblBacteria" id="ACU69360">
        <property type="protein sequence ID" value="ACU69360"/>
        <property type="gene ID" value="Caci_0408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0408"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="GTGAHKT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="48"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="48873" checksum="92888FDC44A9B30C" modified="2009-10-13" version="1">MPQTDSLARDAERVGSGAEARFDSDARSGSGSGSSSGSARSVGSPKLTLFAALLGFVMIALDASAVNVALPAVGRGLGGSTAGLQWIVDAYTLMFAALLLSAGAFSDRLGASRLYGGGAAAFTLASVACGLAPSLGFLIGARLVQGSAAALMLPSSLALVRQAFPDASARAAAIAQWTMAGAASTAVGPVLGGALTSSVSWRSIFFLNLPVGLVILGALRRTERSVRRPAPLDLPGQLTAIVGLAALTYGVISGGASGFGRPQAWASVLLALVSFGAFGVVEHRATEPMLPLGLLRDRVVAVCLAVGFVVNAAYYGLIFVFGLFAQDILGRSAVGAGLVFMPTAILCTITNLFSARAAARWGARTPVLVGQLACAAGLLVLLLVNTHTSALELALLLLPLAGGLGFAVPSLTAMMLSGIAPERAGLAGGVLNSFRQTGGALAVAGFGALVAQHGGFVTGLHVSLLISVALLAVTTLGTLALPKVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVP2</accession>
    <name>C7PVP2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ordered locus">Caci_2366</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2366"/>
    <dbReference type="EnsemblBacteria" id="ACU71284">
        <property type="protein sequence ID" value="ACU71284"/>
        <property type="gene ID" value="Caci_2366"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2366"/>
    <dbReference type="eggNOG" id="COG0173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014330_3_2_11"/>
    <dbReference type="OMA" id="YQLDVEM"/>
    <dbReference type="OrthoDB" id="226836at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:aspartate-tRNA ligase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
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        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GAD_dom"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="138"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="195"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
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        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
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        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="531"/>
            <end position="534"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU71284.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="586" mass="64502" checksum="41B810E87ACBDD96" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVV8</accession>
    <name>C7PVV8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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    </dbReference>
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        <property type="gene ID" value="Caci_2432"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19261" checksum="9A5E37571FEAC163" modified="2009-10-13" version="1">MEEGVEEVKVDVDQLQHVEHIVPDRKLRAVPVLLLSCIVFGLASAAFAWTTLRVHDRQMSAEANEKAVAFVLGTPGLQTSEQPATGGGSVTAFYSPKLHRFAITGHDLPSLTGGRTYEFWYRTSPDAAPKPVGNSRFNGPQNDVVVVSLPAQVTAVEVTVEPSGDAHTPSSAPIAELKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWN4</accession>
    <name>C7PWN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795043.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6463"/>
    <dbReference type="EnsemblBacteria" id="ACU75314">
        <property type="protein sequence ID" value="ACU75314"/>
        <property type="gene ID" value="Caci_6463"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6463"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="AGCTVAM"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="22"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="50790" checksum="C309A7B334004DFE" modified="2009-10-13" version="1">MSLPHARNFIDGRWSDAPTAGTTSSPATGMPIGTYADDGAASARNAIDAARRTFRAGTWARDRRLRARALSEMADRMAQRRDELVDLLSRENGKRRAEAAMEVDAAIPKLRYNAALALTDTGRAAETSPSSYSMTIHQPAGVAAVIVPWNSPVILAVRSFAPALAAGCTVAMKMPAQTALTNGLLYEIIAETTALPAGAVNAFTESGDDGARLLVTDPGTDVVSYTGSTAVGRTIMAEAARHVKGCSLELGGKTPMIVFDDADLDAAVPVLTAAVTTFSGQFCMAGSRILAQRSVADELRARLTAALEAVPVGPDQDHESAMGPVIDRTQALRIDAIVAASSAWGSILLRGGLVTDGNDAYLRPSLVEIDDVSAPLIHQEVFGPTATFEVFDHESDAVTRANATEYGLAASVWSRDVDRPLRVGRQLDVGTVWINDWAVIHDQFEEGGFKQSGIGRLNGPRGLAEFQEIKHFVHSPGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR5</accession>
    <name>C7PWR5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796897.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8349"/>
    <dbReference type="EnsemblBacteria" id="ACU77172">
        <property type="protein sequence ID" value="ACU77172"/>
        <property type="gene ID" value="Caci_8349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8349"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026766_0_0_11"/>
    <dbReference type="OMA" id="GLWYAFT"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="Purple_acid_Pase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="SSF49363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981322" evidence="3">
        <location>
            <begin position="36"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Pur_ac_phosph_N" evidence="5">
        <location>
            <begin position="73"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="4">
        <location>
            <begin position="220"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="57140" checksum="4A6C3392F8087E64" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR8</accession>
    <name>C7PWR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796900.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8352"/>
    <dbReference type="EnsemblBacteria" id="ACU77175">
        <property type="protein sequence ID" value="ACU77175"/>
        <property type="gene ID" value="Caci_8352"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8352"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WARINRH"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="101"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="19365" checksum="611C2FD6CF9B4EDB" modified="2009-10-13" version="1">MRASAEAEYKNYVTARSHALWHTAFLMCGDAHQAEDVVQTALLKLYVAWHRVERAENRDAYVRRVLVRCVIDEKRRGWRRERSVAAVPESPAPDGPDIGERDAVLQALAQLAPRQRATLVLRFWEDLSIEQTADLLGCSSGTVRSQTARGLATLRGILLDQQATALGRAEKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWZ4</accession>
    <name>C7PWZ4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tilS</name>
        <name evidence="10" type="ordered locus">Caci_8428</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796976.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8428"/>
    <dbReference type="EnsemblBacteria" id="ACU77251">
        <property type="protein sequence ID" value="ACU77251"/>
        <property type="gene ID" value="Caci_8428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8428"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_1_0_11"/>
    <dbReference type="OMA" id="PWQDPHN"/>
    <dbReference type="OrthoDB" id="666797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="8">
        <location>
            <begin position="27"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="TilS" evidence="9">
        <location>
            <begin position="257"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="32"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU77251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="37262" checksum="74DCD515C71D999F" modified="2009-10-13" version="1">MGPAPAVAAIRLAVRKTLSGLAPGGLVLVACSGGADSIALACATAFVAPRLSLRFGGLTVDHNLQEGSAAQAERVVRFLASLGFDPVESLSVRVEGHGGPEAAARVARYGALDAAAERLGAATVLLGHTRDDQAETVLLGLARGSGARSLAGMPAQAGRYARPFLDLPRATTVAASAAEGFEPWDDPHNADPAYTRSRVRHAAIPALSAALGPGIPEALARTAKMLREDTEALDAWAAREFDRLLEPFGDCDLSHYLDVSELSVLPTAVRRRVLRLAALRAGCPGSDLAAVHIEELDRLLTDWRGQGPLHLPSAVAAARRYGKLAFERSGALRRGGADRSDPGQPAEDPAPAGLLMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWZ8</accession>
    <name>C7PWZ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8432"/>
    <dbReference type="MEROPS" id="S13.004"/>
    <dbReference type="EnsemblBacteria" id="ACU77255">
        <property type="protein sequence ID" value="ACU77255"/>
        <property type="gene ID" value="Caci_8432"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8432"/>
    <dbReference type="eggNOG" id="COG2027">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017692_0_2_11"/>
    <dbReference type="OMA" id="HSDNTLA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982633" evidence="3">
        <location>
            <begin position="30"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="508" mass="49924" checksum="9712C721FD392EB8" modified="2009-10-13" version="1" precursor="true">MARQVPGTLPTAIVSAALGIVLAAGCVWAAGPWSGGQRVSERADASRDGAVPVARTSQGSLAPSSAAPSTRSAGPAHVPAGAALSPVLAGDKPGGALTAAELAGALQPLTLAPGLGKHVGIAVADPASPALLFDEHAADGFAPASTNKVVTAVAALSALGPDDRFATRVVQGPDSAATPTIVLVGGGDPTLSTQGPSSDPGYQPASLDDLAARTAAALQAKGVKSVTLGYDASVFSGPGLNPTWSPDYTDGNVAPVTGLMVDEGRAKAANDLSPRVTDPAALAAVDFAGRLAAHGVQVTGKPATASAGSGAELARVTSPRLANLVEHMLTVSDNDLAESLLRHVALADSKPATFDGGVAAVRDQLGKLGLDLTGLNVLDGSGLSRKDSITPAFEVKVLSTAAADDHPELRAALTGLPVAGFTGTLDEDGRYTTAPSLAGAGLVRAKTGSLTGVVTLAGLVRDSSGQLLVFSLMADEATDSTAARAAVDRLATTLAGCGCGGGTAPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX91</accession>
    <name>C7PX91_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0492"/>
    <dbReference type="EnsemblBacteria" id="ACU69442">
        <property type="protein sequence ID" value="ACU69442"/>
        <property type="gene ID" value="Caci_0492"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0492"/>
    <dbReference type="eggNOG" id="ENOG5032R1N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050216_0_0_11"/>
    <dbReference type="OMA" id="ACTAHEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026367">
        <property type="entry name" value="FxsC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04276">
        <property type="entry name" value="FxsC_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="45045" checksum="6DA1AE78343CD64A" modified="2009-10-13" version="1">MPHFFFSYSRKDAPDEYLYRFYDDLCREISVRSHFTIESAGFIDKNQPVGGEWEDSIGVALGTCDVFVPVYSPSLFGSSNCGQEWHAFGTRQSRAGKLAPHIVPVWWVPTPGELPTIADRIQDTRSQFGAEYQKYGLRYLMQLKENESLYRDFLVKFTMMVLAAGENPPELMRDLSLAGAPNAFALKPETTGGRARPRSGLKAGGIKSVRFVVAAGSRDEMRTIRAAVDAYGAGSLDWQPYHPEHPDPIVLHAQGVAIAHRMVSSFKAAMDDDLFELLERCQASREPVVLIVDPWVVELDAYKDLLARLDTARFGTTAVVVPWESGATIESNLRDILTVHLGNWMYAGERFFRDDIRSMGEFEANLGEVLVDMWSRIVKWSDAVRRVDESGPASRPILTGPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX92</accession>
    <name>C7PX92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784738.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0493"/>
    <dbReference type="EnsemblBacteria" id="ACU69443">
        <property type="protein sequence ID" value="ACU69443"/>
        <property type="gene ID" value="Caci_0493"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0493"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_291649_0_0_11"/>
    <dbReference type="OrthoDB" id="1472435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="845"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="877"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="CbiA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="570"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1046" mass="116108" checksum="31ADAF1079EC8D28" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXD5</accession>
    <name>C7PXD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784781.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0548"/>
    <dbReference type="EnsemblBacteria" id="ACU69486">
        <property type="protein sequence ID" value="ACU69486"/>
        <property type="gene ID" value="Caci_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0548"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_14_0_11"/>
    <dbReference type="OMA" id="IGLDQWF"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="44182" checksum="F5DD431C96164277" modified="2009-10-13" version="1">MTAQAIVSDQRQSNYRQVFAIREFRYVFTAHSASMLGSVVTDVSLSVLVLERTGSPFLAALTFALGFMPYAFAGTLLAGIGDRYPARLLLVTCNCVSAATVAVMAMPFTPIWALIVLRFAASTIQPIFTSARAASLPEFLKGDRYTLGRSILRIVNQSTQIIGYATGGLLLLVIQPRQALWIDAASFAVSAVLLRVGTVGRPARITDRKAQGTLIRESLSGARAVVRQPRIRALLFLWWTAPALAGIPEGLAAPYVRQIHAASVSVGLLMASAAVGTIGGEVAIGTLVGPARRMRLVVPLASCSLLPLAVFVLRPDVIVAIALMGLTGVADAYMLGLDQWFLEAVPDELRAQAFSIMFAGIMLTQGLTISIGGLAAEFAAPSLVIAISAAVGTVVIALVCRSVLRTAPSPSSEESISVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF7</accession>
    <name>C7PXF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786703.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2492"/>
    <dbReference type="EnsemblBacteria" id="ACU71410">
        <property type="protein sequence ID" value="ACU71410"/>
        <property type="gene ID" value="Caci_2492"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2492"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="AYRIEST"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="219"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34558" checksum="F73F0D6875CE4BAB" modified="2009-10-13" version="1">MDVLTDALTAMRSGQTRSARTEVRAPWGLRFGAIGGTAFHVLLRGRCWLLPPSGEPVEMAVGEVTLVRHGNSVALADDPATPLQDFRPAGWRPGQTIGRVDVEGSGERSLLLCGAYQLGRTRPHPLLAELPDLLLLRADETPGLAATVTLLGAELEHAQPGQDGVVPALVDALLLLILRGWIERSARADPARTDTAGTDTARTITALGWPGALTDPAISSALTDLHDDPGRAWTVAELGDRAGLSRSAFAQRFTALVGEPPLTYLTWWRMTIAGRMLRESDAPLSTVAQRVGYASEFAFAKAFKREFGIAPGRYRREVAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYG2</accession>
    <name>C7PYG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795181.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6606"/>
    <dbReference type="EnsemblBacteria" id="ACU75452">
        <property type="protein sequence ID" value="ACU75452"/>
        <property type="gene ID" value="Caci_6606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6606"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="FASWRYV"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="18"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="552" mass="56275" checksum="04AFEB8AFE01909E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYJ1</accession>
    <name>C7PYJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8490"/>
    <dbReference type="EnsemblBacteria" id="ACU77313">
        <property type="protein sequence ID" value="ACU77313"/>
        <property type="gene ID" value="Caci_8490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8490"/>
    <dbReference type="eggNOG" id="ENOG5032SYR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902220_0_0_11"/>
    <dbReference type="OMA" id="RRWYIAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982624" evidence="3">
        <location>
            <begin position="27"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32416" checksum="39F13BF0972E6FF9" modified="2009-10-13" version="1" precursor="true">MLRVMLRRWYVSIPALIVAVALPAAAWTMISSKYLSTSTISLLNSTAASSANQRTGNPFLAFDSSLTPMADFLARRLGSDQSAADLAARGVVDPASAVLAPNASGPFLTMTVTGKDQALVLTELQTFDQYAIEQLAVIQTTTTASLPPSTLIRAVVVVPPQKPTTSMKSKFEDVAGAGVFGLAILFLAVFGSESLALRRARARAGLPRRHDTGGAASPGGGRGGREARAGRTDTGADEPAALGSGAGTGTLARRAPALSSAAQLPRYRDPEFDPEDEDEHEHETEPWIDVEPLPLEHLAVTDRDPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM7</accession>
    <name>C7PYM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797074.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8526"/>
    <dbReference type="EnsemblBacteria" id="ACU77349">
        <property type="protein sequence ID" value="ACU77349"/>
        <property type="gene ID" value="Caci_8526"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8526"/>
    <dbReference type="HOGENOM" id="CLU_441259_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="619" mass="61347" checksum="154674DF1CCED724" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE9</accession>
    <name>C7PZE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786899.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2691"/>
    <dbReference type="ESTHER" id="catad-c7pze9">
        <property type="family name" value="Haloperoxidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71606">
        <property type="protein sequence ID" value="ACU71606"/>
        <property type="gene ID" value="Caci_2691"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2691"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_12_3_11"/>
    <dbReference type="OMA" id="DMWEYQM"/>
    <dbReference type="OrthoDB" id="1282004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="30108" checksum="41DD11CB1A2197FA" modified="2009-10-13" version="1">MPYVTVGEENSAPIEIFYEDHGQGRPVVLIHGFPLSGRAWERQERALLAAGRRVITYDRRGFGRSSQPTTGYDYDTFAADLDKLLAALDLTDVDLAGHSMGGGEIARYLGTYGSARIGKAVIVSGVPPYLLKTAETPQGVPQEVFDEIAGALVADRFGYFTEWNKSFFNLDETLGKRISPEAVQDAWNTAVSASPTGTIACVATWITDFRADLPKIDIPVLVLHGTADRILPIDATGARTHELIKDSEYVAIEGADHGLCWTYAEEVNAELLRFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS2</accession>
    <name>C7PZS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Allantoinase</fullName>
            <ecNumber evidence="4">3.5.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4726</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.5" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793316.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4726"/>
    <dbReference type="EnsemblBacteria" id="ACU73587">
        <property type="protein sequence ID" value="ACU73587"/>
        <property type="gene ID" value="Caci_4726"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4726"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_4_0_11"/>
    <dbReference type="OMA" id="WVTAEVT"/>
    <dbReference type="OrthoDB" id="906155at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017593">
        <property type="entry name" value="Allantoinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03178">
        <property type="entry name" value="allantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="55"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="443" mass="46734" checksum="302DF8D493B73DB6" modified="2009-10-13" version="1">MSGPFDLVLRSTRAVLPDGVRPAAVAVRRGRIAEVGDHRAAFGARVDLDLADTALLPGLVDTHVHVNEPGRTRWEGFASATRAAAAGGVTTLIDMPLNSIPPTVDVPALAVKRKAAEGKCFVDVGFWGGAIPGNGAALRPLHRSGVFGFKCFLADSGVEEFPELSVAEMRLAMREIARFGGLLIVHAENAEALGAAPSSVRYRDFLASRPAVAEDSAIADVIDAARAYRARVHILHLAAAEALPRLAAAKADGVRISAETCPHYLTFSADEIRDGATQFKCCPPIRDAADREALWAALADGLIDVVVSDHSPSTPDLKRLDSGDFGAAWGGISSLQLGLAAVWTGARARGFGLADVARWMAARPAELVGLAGKGRIAVGYDADLVAFDPEAAFTVDPANLHHKNPVTPYAGRELHGVVRATYLRGEPVTDVPRGGFLTHPEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0K5</accession>
    <name>C7Q0K5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784928.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0698"/>
    <dbReference type="EnsemblBacteria" id="ACU69633">
        <property type="protein sequence ID" value="ACU69633"/>
        <property type="gene ID" value="Caci_0698"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0698"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087539_3_1_11"/>
    <dbReference type="OMA" id="ATFYVHY"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="19994" checksum="10CDE21AF9CB244E" modified="2009-10-13" version="1">MSGVQDPRAARTRARLRAALLEACAEQPLSDVSVAEVVQRAGIGRATFYLHYPALEELAVDACADVVRDAVEALHAWRGIPDPATPPPPLEEFFSSLEQHRAVYTALMTPGGGGPLGSVLHRDLRERSRRERELAGAPEAELVAAAVAGTFAGVLADWLHGLVPGTATEVAGRVWRLLISLHRTPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0V9</accession>
    <name>C7Q0V9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin-dependent monooxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">TetX monooxygenase</fullName>
            <shortName evidence="1">TetX</shortName>
            <ecNumber evidence="1">1.14.13.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a tetracycline + H(+) + NADPH + O2 = an 11a-hydroxytetracycline + H2O + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:61444"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:144644"/>
            <dbReference type="ChEBI" id="CHEBI:144645"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aromatic-ring hydroxylase family. TetX subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785032.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0802"/>
    <dbReference type="EnsemblBacteria" id="ACU69737">
        <property type="protein sequence ID" value="ACU69737"/>
        <property type="gene ID" value="Caci_0802"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0802"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_4_0_11"/>
    <dbReference type="OMA" id="EGQAMRI"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00845">
        <property type="entry name" value="TetX_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043683">
        <property type="entry name" value="TetX_monooxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1 3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="288"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="39648" checksum="AC96AD9EDF820DC1" modified="2009-10-13" version="1">MTIAIIGAGLGGLALARVLHVNGIEAVVYERESSRAARGQGGMLDIHSGTGQRALREAGLIDQFHAIARGEGQDMRLLEPDGTLLWQEDTPDDAPLARPEVDRADLRGMLLDSLPDGTVRWGRAFASAEDGMVRFADGSSAPYDLLVGADGAESRVRALLTDARPAHTGQNIVELGIPDIDRTHPDLAAMVGRGNYWVLGDGQSLGAQRNGDGRVRVYASFHPTPADWFATSGIPFDDPAAARERLLELFSGWHAKFRALIAACDDTVQPRPLTTLPVGLTWPSKPGITLLGDAAHLMPPVGQGANMALLDGALLALALASHPDDFSAAVKDYETEMFERSAKVGQMSARMQEMVTAPDAARRMLAFFQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q186</accession>
    <name>C7Q186_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage major capsid protein, HK97 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787054.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2852"/>
    <dbReference type="EnsemblBacteria" id="ACU71761">
        <property type="protein sequence ID" value="ACU71761"/>
        <property type="gene ID" value="Caci_2852"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2852"/>
    <dbReference type="eggNOG" id="COG4653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_613538_0_0_11"/>
    <dbReference type="OMA" id="FHRFDCV"/>
    <dbReference type="OrthoDB" id="755947at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="50332" checksum="674DA9DD481D076B" modified="2009-10-13" version="1">MTTIAIPTSSAELEEWMNDGERMTNVLKEGKFKEFVGNYQSANAKTDPDLKAQIAEQVQLGFAQFMKDNGEKGDIPPVDMTPGPAAMPRVHLENGARRSSAEKALNGQRAIGRALDGMFQDSAEFFRATHFDEMRVNRSADLSAKRSKVTEIMNSFGSEVPADGGFLIPETLRSNLLQVALEQAVVRPRAQVIPMETLRVPIPMIDSTSNVSSVFGGVICYWTEEAAALVESQASFGRVTLDAKKLTGYAEIPNELLADAPAFTSFFDDVFPRALAWYEDIGFMNGTGAGEPRGFVNCPASVAVAAEAGQPSGTIVWENIVKMYARMLPTALQNAVWIASIDTFPQLATMALSVGTGGSAVWLGNLQQPGSAVPPVSILGRPVIFTEKTPALGSLGDINFVDLSYYLIGDRQMMQSTSSPHFKFASDKTVFRIISRLDGQPWLQSPITPHNGAGALSPFVSLAARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1A2</accession>
    <name>C7Q1A2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71777">
        <property type="protein sequence ID" value="ACU71777"/>
        <property type="gene ID" value="Caci_2868"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2868"/>
    <dbReference type="eggNOG" id="ENOG502ZDNB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154777_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="26696" checksum="30A507920982B773" modified="2009-10-13" version="1">MNNVPTPTACVGPCNSGWRRAETARLTKGTPHELTARAGQPVWCNPCARHVRIGLADFPELAARLMLEVENATAAGTVHVSGSKGRPIHGRERYTFCIDDIVGVLNYWAEAIRVDRDLAAPPPRSRGAAITADTRLLLIHFDWMIAEHSEPAQSAEFGKDLNRLYRHAAKLTRTDDVRAVPCEGIPCRQCDLMALEHELDWQGRATGYVLCRDCGTLLKEDEYERWVKLAAQPFKKRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1H2</accession>
    <name>C7Q1H2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane bound protein complex subunit MbxA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4840"/>
    <dbReference type="EnsemblBacteria" id="ACU73701">
        <property type="protein sequence ID" value="ACU73701"/>
        <property type="gene ID" value="Caci_4840"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4840"/>
    <dbReference type="eggNOG" id="COG1863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1530880_0_0_11"/>
    <dbReference type="OMA" id="WAFAVWI"/>
    <dbReference type="OrthoDB" id="2095979at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002758">
        <property type="entry name" value="Cation_antiport_E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34584">
        <property type="entry name" value="PTHR34584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01899">
        <property type="entry name" value="MNHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="18383" checksum="E55B70410D012CF3" modified="2009-10-13" version="1" precursor="true">MSKRSNALVRVFALACWCMGVWVLLTWTRTAEQIAVGAVVSVAVAVALAPLGAVAGPWRLLDPRVAARVAGIVVVALGRVVWANVLLARRVWSPSLPLRSGMVIVPTTQRGALGLTVVGVVSSLIVDNQLVDVDAARGRLLYHAVDVPPRDAAQARERINGPLERFLPEERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y4</accession>
    <name>C7Q1Y4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6844"/>
    <dbReference type="EnsemblBacteria" id="ACU75685">
        <property type="protein sequence ID" value="ACU75685"/>
        <property type="gene ID" value="Caci_6844"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6844"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_4_11"/>
    <dbReference type="OMA" id="KERTEWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1468" mass="159274" checksum="31330306F76C8D06" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q211</accession>
    <name>C7Q211_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8733"/>
    <dbReference type="EnsemblBacteria" id="ACU77548">
        <property type="protein sequence ID" value="ACU77548"/>
        <property type="gene ID" value="Caci_8733"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8733"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_11_0_11"/>
    <dbReference type="OMA" id="VYHYFPG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="23407" checksum="1B6976DEA540E118" modified="2009-10-13" version="1">MQSESRSSQPVRSTPRTAPRRRLSVDRRRDELIEAALDLLAERGPDEVSVDDVAQAAGASRALVYHYFGTKQELYAAALSKAAAELTRRLAQIEPGDTPLQRLDRAVRAFVEFAEAHSAGFVALLGGSAAYGSGGESAALVHSVEDTVYELLVEGLGEPTPVDPLVRMTLKCWVAAAETAVLDWLKHQDLPRTEIEQQLIIQLGALLMAIGHEVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2L7</accession>
    <name>C7Q2L7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prevent-host-death family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785154.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69859">
        <property type="protein sequence ID" value="ACU69859"/>
        <property type="gene ID" value="Caci_0927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0927"/>
    <dbReference type="HOGENOM" id="CLU_2913951_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="6779" checksum="4EF0F0DA8EB3A176" modified="2009-10-13" version="1">MEAAYTLDDARALFPDLVEEARITRHPVYVTDDAGEPVVAIVDMHWLEECEKLMAQSGTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2N5</accession>
    <name>C7Q2N5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ordered locus">Caci_0945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785172.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0945"/>
    <dbReference type="EnsemblBacteria" id="ACU69877">
        <property type="protein sequence ID" value="ACU69877"/>
        <property type="gene ID" value="Caci_0945"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0945"/>
    <dbReference type="eggNOG" id="COG0096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098428_0_1_11"/>
    <dbReference type="OMA" id="FDQGYIL"/>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14344" checksum="FF087820F8E0F948" modified="2009-10-13" version="1">MTMTDPIADMLTRLRNANSAYHDQVTMPSSKIKTHICEILKQEGYIASWKVEDAEVGKSLTIELKFGPNRERSIAGIKRISKPGLRVYAKSTGLPKVLGGLGVAIISTSTGLLTDRQAARKGVGGEVLAYVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Q5</accession>
    <name>C7Q2Q5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787090.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2888"/>
    <dbReference type="EnsemblBacteria" id="ACU71797">
        <property type="protein sequence ID" value="ACU71797"/>
        <property type="gene ID" value="Caci_2888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2888"/>
    <dbReference type="HOGENOM" id="CLU_2300725_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="10568" checksum="B4FD539FA3DC657A" modified="2009-10-13" version="1">MHSSIPQLALVPEPRTCPPWCTEHDADTNLCIGTRTDLTYPAGYPSGVTLTSASVQLMQDPDETQPTIALTLNSVPLDLAGQQAENLALALLRALGKAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Z1</accession>
    <name>C7Q2Z1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2974"/>
    <dbReference type="EnsemblBacteria" id="ACU71883">
        <property type="protein sequence ID" value="ACU71883"/>
        <property type="gene ID" value="Caci_2974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2974"/>
    <dbReference type="HOGENOM" id="CLU_2680930_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="8006" checksum="FCE02ADACA1C3AF1" modified="2009-10-13" version="1">MVAMDIPAKLTTLHAETQAVFKLLHAANNNAHQQDPSLRQAVALTSAAVAALEKATRCAEAAFEAERVAEREHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q368</accession>
    <name>C7Q368_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793533.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4944"/>
    <dbReference type="EnsemblBacteria" id="ACU73804">
        <property type="protein sequence ID" value="ACU73804"/>
        <property type="gene ID" value="Caci_4944"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4944"/>
    <dbReference type="eggNOG" id="COG0655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_2_1_11"/>
    <dbReference type="OMA" id="WVGTGMM"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21376" checksum="0C1AABB4F3A94D9C" modified="2009-10-13" version="1">MSSITVGIAYTSGYGHTRELANAVAEGAASIPGTRVAMIDVAAVTDDDWQTLDGCHAIVFGSPTYMGSASGAFHAFAEATSGRWTTRAWQDKIAAGFTNSGSMSGDKLHTLQYFSMLAAQHGMHWISLGLLPGWNTTTASEDDHNRLGFYLGAGAQTWNDQGPDAVHAADVSTARHLGRRVATHTRRFADAFDPAEVGAATAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3F7</accession>
    <name>C7Q3F7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795450.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6884"/>
    <dbReference type="EnsemblBacteria" id="ACU75722">
        <property type="protein sequence ID" value="ACU75722"/>
        <property type="gene ID" value="Caci_6884"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6884"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_9_4_11"/>
    <dbReference type="OMA" id="MQNREIT"/>
    <dbReference type="OrthoDB" id="1669868at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="23068" checksum="1317BED6CA1C39D3" modified="2009-10-13" version="1">MVARRFNGLIFDFFGVLTSNMVEVIECFEDREKIARGTFLRAWADPRGRDLFTRLELGEISQTDWNSGFAALMGVAPDDLMSRYLYDAFPAHEVLKVARQARAAGYKTAVLSNSLGRTPYDPYAGFDLLGNFDEVVLSQNHGLRKPDPAVFQLVLDKLGLPAEECVFVDDSEENLQAAVDLGMTIVFALDERELSARLRTLLGLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U3</accession>
    <name>C7Q3U3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797425.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8888"/>
    <dbReference type="EnsemblBacteria" id="ACU77701">
        <property type="protein sequence ID" value="ACU77701"/>
        <property type="gene ID" value="Caci_8888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8888"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070320_2_1_11"/>
    <dbReference type="OMA" id="HPPVELH"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004115">
        <property type="term" value="F:3',5'-cyclic-AMP phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="5"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="26904" checksum="BE21E61E1145EB6D" modified="2009-10-13" version="1">MPVVIAHVSDIHIDAGPRAAERTRRVFDHLDALPADLDLVVLTGDIADHGLDSEYETVRQATATRHPLLVCPGNHDDREAFRRALLGVPASTGPINQVHRTDRFVVALCDSSIPKQDDGFLADETLAWLAAELDATPDGVPVLIGFHHPPVELHTPFVDKIRQFGEERLAEAVAGRQNVVALLAGHAHTAAATHFAGLPLLVAPGVVSTIPLPWEGERALHLDHQPSLAFHVIDDRHRITTHFRSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U6</accession>
    <name>C7Q3U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797428.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8891"/>
    <dbReference type="EnsemblBacteria" id="ACU77704">
        <property type="protein sequence ID" value="ACU77704"/>
        <property type="gene ID" value="Caci_8891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8891"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_1_11"/>
    <dbReference type="OMA" id="CYEHNTL"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="29455" checksum="21F52E09F7C0491E" modified="2009-10-13" version="1">MDFDLDAYLARIGYTGERTATAATLGALQRTHIYAIPFENLDPVRGVVPSLDLDDLTAKLVHGTTRGGYCYEHNTLYAAALRALGFQVTVLAGRVLVGAKPGDQRPRTHMLLLAETPDDPHRYLTDVGFGSEGALLDPMPLAPADVRDQPRHHRLSITPADSPLEQWVLRAFLDGQWRDQYSFTVEPFYAPDFGVINYYIASSPRSPFSSRVYACRTYPDRQLKLDARAFTVTQNDGTSVTRDLADDAEVRQVLADEFGIVAPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3V0</accession>
    <name>C7Q3V0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797432.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8895"/>
    <dbReference type="EnsemblBacteria" id="ACU77708">
        <property type="protein sequence ID" value="ACU77708"/>
        <property type="gene ID" value="Caci_8895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8895"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_39_5_11"/>
    <dbReference type="OMA" id="NDWIIMA"/>
    <dbReference type="OrthoDB" id="446363at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="455" mass="48597" checksum="43BAC32A331B7888" modified="2009-10-13" version="1">MTDSAPAPSPTSESAGDSVWRVVGASMVGTTLEWYDFFLYGTAAAVVFPKVFFVKSDPLTATLLSFLTYALGFAARPIGGVVFGHIGDRAGRKKTLMASLVIMGIATTGMAFVPGYSSIGVWAPVLLTSLRMVQGFALGGEWGGSVLIVAERDKTRRGFWASWPQAGAPLGLVLGTGVIILLSQNMSEKSFLDWGWRVAFGLSAILLVVGFWVRRSLNETEAFRAAQAKKDSAPPKLPVLEVFRTSWREILIAFGSRMAENISFYLVATFSVTWITQHLKLSKSFGLDAVMVGAAVETVLIPLFGMLSDRIGRRPVYLAGAIGIGIWTPIFFALVDQKSYPLAVLAVTVALAFHGLMYGPQAAFFAEMFPTGVRYSGASIGYQVASIAAGAPAPLIAVAILQHNGGKTSAWLTLYMGLAAVATIVALYFARETRSVSMSGQSSAEPAEELHDVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q452</accession>
    <name>C7Q452_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785206.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69912">
        <property type="protein sequence ID" value="ACU69912"/>
        <property type="gene ID" value="Caci_0981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0981"/>
    <dbReference type="HOGENOM" id="CLU_1025612_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="28732" checksum="4E684B79DB965C00" modified="2009-10-13" version="1">MTEHESDDHLRVLFRGADLDDVPVTRDLIGPAVAWGDGRRRRDRWRAVGATGAVAAVAVAGIVALRPAGADGVAPSSPVSPVSQSIQRELSTLRPFLPAGYTLTCQNTEGVFCAIFVLTSPAGGTSLVFWHTGMNIPLEDGPPSLADTVHVHEQGTQTFANGSMAILAYDLEARGMGSATAEELTDPTEIVGNQVTYTFTPDGSPRTYGIEMAQMVKDMPWKSGTSKSPDDRARFGYNPGGPVLSTEQFDRMASAPGFLSALAQVVDWGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4I0</accession>
    <name>C7Q4I0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3040"/>
    <dbReference type="EnsemblBacteria" id="ACU71949">
        <property type="protein sequence ID" value="ACU71949"/>
        <property type="gene ID" value="Caci_3040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3040"/>
    <dbReference type="HOGENOM" id="CLU_2615522_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982881" evidence="1">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="8156" checksum="B5038C908E4E7EC1" modified="2009-10-13" version="1">MTALTIVLLPVRTPGAATPPPLVHSGCLVCTGTKRAFCGRKVADPLPAASAAKAVTTCVVCIDFEKSHNWAAHFWGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M1</accession>
    <name>C7Q4M1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787283.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3081"/>
    <dbReference type="EnsemblBacteria" id="ACU71990">
        <property type="protein sequence ID" value="ACU71990"/>
        <property type="gene ID" value="Caci_3081"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3081"/>
    <dbReference type="eggNOG" id="COG1732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038355_1_2_11"/>
    <dbReference type="OMA" id="GSREVYM"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981416" evidence="2">
        <location>
            <begin position="29"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="39"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="31841" checksum="65EC3A42596B4E7E" modified="2009-10-13" version="1" precursor="true">MRIRTTGSNTRVVGAALAVALAATGALSACSSSSKSGSKVVVASAAFPENVLLMEIYAQALEDKGISVERKPNVGQRDVLFQQLKSNAITVVPEYNGALLAYLDKSSTESTQSGVDSAVTAKLPSNLQILNPAAAQDNDSLVVTQALATKDNLKKISDLAPYAKDLVLGSAPEFKTRQQGVLGLQSQYGLTFKDFKALDNSGPQTVSALQHGDADVVDLYSTTTAIKTNGFVVLDDDKGLFGVQNVIPLVDKGKLSPAGIDALNAVSAKLDTTTLTSLLEQVVTQKKDESDVAKAWLASVGLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S2</accession>
    <name>C7Q4S2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3132"/>
    <dbReference type="EnsemblBacteria" id="ACU72041">
        <property type="protein sequence ID" value="ACU72041"/>
        <property type="gene ID" value="Caci_3132"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3132"/>
    <dbReference type="eggNOG" id="COG2949">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051474_0_0_11"/>
    <dbReference type="OMA" id="YDEPDAM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981418" description="DUF218 domain-containing protein" evidence="1">
        <location>
            <begin position="43"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="57"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="25436" checksum="6B463C67B8ED1F30" modified="2009-10-13" version="1" precursor="true">MTRIQPRRWLPRTRKSQRRLYQAAALAVVLMFAPVTAVHAYASPYQRSAAAVPYEPVAIVFGAGAPGGRPSPYLSRRLDVALDLYRRGKVTVILVTGDNSQPDYDEPSAMRQYLVERGVPAARIVRDFAGFDTWASCERAKKIFGVDHATLVTQDFHLPRALLLCRAAGIDAYGVADTGESAAGEDELVNDSAREVLAGIKAWGQAVFQPQPVLGKKETSVATALAAAKGARSSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4V0</accession>
    <name>C7Q4V0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793627.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5038"/>
    <dbReference type="EnsemblBacteria" id="ACU73898">
        <property type="protein sequence ID" value="ACU73898"/>
        <property type="gene ID" value="Caci_5038"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5038"/>
    <dbReference type="eggNOG" id="ENOG502ZMI1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1666233_0_0_11"/>
    <dbReference type="OMA" id="CKANDTY"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982784" description="Ricin B-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="40"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="16983" checksum="AE91B9C1E6625F23" modified="2009-10-13" version="1" precursor="true">MSRLKKKLAGIAAVAVATPLVMLGAASTAGAASTITWKTSGNCLGYGLSTFGNNVSNLNQVLTIDCSAPGFQSVSWIDSSVGSAWLEHPDVDTSLCLTAYKDHSVYFEHCKANDTYEQWREIHVGSIWHLQNVATGEYLRGGGNRQQVYTNAAPQAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5X0</accession>
    <name>C7Q5X0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785361.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1141"/>
    <dbReference type="EnsemblBacteria" id="ACU70067">
        <property type="protein sequence ID" value="ACU70067"/>
        <property type="gene ID" value="Caci_1141"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1141"/>
    <dbReference type="eggNOG" id="COG0362">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_4_2_11"/>
    <dbReference type="OMA" id="QALYMGK"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="180"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="51846" checksum="503AF14AC0788C6E" modified="2009-10-13" version="1">MQASAQIGVTGLAVMGRNLARNFARHGYTVALHNRTAARTHALVEEFGSEGTFVPTETAEEFVAALERPRRLMIMVKAGEATDAVIEEFAPLLESGDMIIDGGNAHFLDTRRREKALRERGIHFVGSGVSGGEEGALHGPSVMPGGSAESYAVLGPMLEAISAKVDGEPCCTHIGTDGAGHFVKMVHNGIEYADMQLIAEAYDLLRNVADYSPAQIAEVFRGWNKGRLNSYLIEITAEILAHTDAATGKPFVDIVRDAAEQKGTGRWTVQTALDVGSPATAIAQATFARVASSRTALRETYRAQAGGTEHPLRAHETERYVATVEQALYASKVIAYDQGWTMIRDAAEEFGWDIDLADVAAIWRGGCIIRAAFLDRIRAAYTGDATLPSLLSEPEFADEIAKAQVSWREVIASAARRGIPVPAFSAALAYFDTLSADRLPAALIQGQRDFFGAHTYHRTDRDGAFHTRWAETGRPEVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q671</accession>
    <name>C7Q671_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Antibiotic biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787370.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3169"/>
    <dbReference type="EnsemblBacteria" id="ACU72077">
        <property type="protein sequence ID" value="ACU72077"/>
        <property type="gene ID" value="Caci_3169"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3169"/>
    <dbReference type="eggNOG" id="COG3491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_3_11"/>
    <dbReference type="OMA" id="WHFGQYV"/>
    <dbReference type="OrthoDB" id="400496at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="187"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="37660" checksum="34937C85FD048001" modified="2009-10-13" version="1">MVTHELGTDPGLPVDPGLPVVDLSKADGSEAERAALHEALRTAATEVGFFQLVGHGITESETAALNDAMRSFFALPHADRLAVSNLNSPHFRGYTGTGDEQTAGARDWRDQMDIGLELPPHVPGAGEPAYWWLQGPNQWPARLPQLRAATLGWIDKLSAISRRLLHELLASIGARPDFYDAAFAGHPHLRLKLVRYPGTAPDGAGQGVGMHKDYGFITLLLQDSVGGLQVARADGTFLDVPPMPGAFVVNLGELLEVATDGYLKATSHRVVSPPRARERFSVPFFFNPRLDAHIEPLEFPHAHHAPGADDDPSNPLYAEFGRNELKGYLRAHPEVTRKFHPDLATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q674</accession>
    <name>C7Q674_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787373.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3172"/>
    <dbReference type="EnsemblBacteria" id="ACU72080">
        <property type="protein sequence ID" value="ACU72080"/>
        <property type="gene ID" value="Caci_3172"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3172"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_13_11"/>
    <dbReference type="OMA" id="SCVAKQV"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="16250" checksum="2577C33A2ABB08B2" modified="2009-10-13" version="1">MTAPPTPAERLADLARLRRVRDRVDREYAQPLDVEALARGEHMSAGHLSREFKAAYGESPYSYLMTRRIERAMAMLRRGDLTVTEVCFAVGCSSLGTFSTRFAELVGMPPSEYKRVSAFAGAGLPSCVSARVTRPIRIREARLGALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6R7</accession>
    <name>C7Q6R7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5243"/>
    <dbReference type="EnsemblBacteria" id="ACU74102">
        <property type="protein sequence ID" value="ACU74102"/>
        <property type="gene ID" value="Caci_5243"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5243"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="WGLYNTK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="21"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="34102" checksum="978E04FB02696650" modified="2009-10-13" version="1">MGNRIEREVTALRAWQVTTHGEPADVMRAVEVPVPEAGAGQVLVRVRGAALNFPDVLMCRGQYQVQPPLPYTPGVELCGEVVGSGERVVGTPVLPTGALAEYALMESDSVYPCPDSLDDAEAAGFLLAYQTGWFGLHRRAKLQPGETLLVHAAAGGVGSAAVQLGKAAGARVIAVVGGPVKAEAARALGADVVVDRREGNFVAAVKEATGGRGADVVYDPVGGDAYQGSTKCVAFEGRIVVVGFAGGTIPAPPLNHALVKNYSILGLHWGLYRAKDPEAVAACHRELTRMAADGTIKTLVGARLSFEEAPAGLTRLAAGENVGRLVVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6R8</accession>
    <name>C7Q6R8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793832.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74103">
        <property type="protein sequence ID" value="ACU74103"/>
        <property type="gene ID" value="Caci_5244"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5244"/>
    <dbReference type="eggNOG" id="ENOG502ZPZK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899224_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="32192" checksum="D83D698305807ECF" modified="2009-10-13" version="1">MAESAPSVTGADRTPRPLLWLGFAAIAGALSVPLAGAAGGLLGDALRGGILALFELVIAGSLLVFSPIAVRKAAGGLLGFAPRKARRVTAIVVVLGLLPWFLEAAVHLSSTDRWQLYWPGWVLYTVVFTLVAAAVALQDVTRAVAVAAVAVLTAAAWLPMRHALVADLADSAVHRLGDPPRSLLRVVSWSDYSSSSYTYRAGVVTRVLDPVTSLPVSDDLTAYLLVSKVGGSTPCDAPFPHGSGDGKLEATPCTPAGDGVWVRGDCEALTLDQGVAVQVIDDQCPGSRQLVEVLRSQRPATDAEILALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6U0</accession>
    <name>C7Q6U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7123"/>
    <dbReference type="EnsemblBacteria" id="ACU75953">
        <property type="protein sequence ID" value="ACU75953"/>
        <property type="gene ID" value="Caci_7123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7123"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_8_1_11"/>
    <dbReference type="OMA" id="FVGQCIS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="409" mass="42688" checksum="69FA4C1BA46DEC12" modified="2009-10-13" version="1">MNTSATPGGTPMGTATGITEVVVIGGGYAGVMAANRLTQREDVTVTLVNPRPEFVERIRLHQLVAGTHAAVADYAKVLSPRVSLLVDSVTRIDAADRSVALAAGSTLRYDYLVYAVGSSATGADVPGVAEFGYPIATMEHARRLKAALEDLPKSFAVTVVGAGPAGIETAAELAEQGRAVTLVTGGALGPSLHEKGRAFVARKLVKLGVTVIDGPGSMVTAVERDGVRLADGRELASALTVWAAGFSVPDLALRSGLSTDAAGRLLTDETLTSVDDVRIIAAGDSAAPSGMPLRMGCQSAVQLGPQAAETVLARLAGRDPAEIDVGFVGLCVSLGRSVGIFQVLHKDDSPRSMYIGGRFGGRIKEFICKGTVWQLKTEGRKPGKHTWWSKDAQRRAKVEALHGKVLTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X9</accession>
    <name>C7Q6X9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795720.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7163"/>
    <dbReference type="EnsemblBacteria" id="ACU75992">
        <property type="protein sequence ID" value="ACU75992"/>
        <property type="gene ID" value="Caci_7163"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7163"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055979_0_0_11"/>
    <dbReference type="OMA" id="DMRWVRD"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981439" evidence="2">
        <location>
            <begin position="34"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="44690" checksum="F3014DE71B60C20A" modified="2009-10-13" version="1" precursor="true">MRPYEKVRRRLRSLAFAGVLLPALLVPAVAAQGASGSPQSVRGSHSGSLATPSAVPGGDPWVVSLGDSYISGEGGRWAGNTDQSSSKIDALGPTAYFDNKDHTAELIPRCHRSLSAEVHIGIAHSLNLACSGARTSTFTEGGYFKPGLDFYNVGGHQGQALMLRDFALKNRVTMVAVSIGGNDFGFGDVVTSCVEHYLAGTLCKNDLAVTSHFNAANAARITKDIASALRNVGLAMASAGYPDNSYKILVQNYPSPIPFGVDFRYPEHYNRQFVGGCGLWNADADWALQTAMPTVTRSIGAAIVDSGLRNIITMDVSRAVGGHKLCEKGVGLLEEVGLNSWKDPGAVDKTEWINQIRIVTFGTDYFQQESLHPNYWSQLGLRNCLRQAYSGPVPHGGVCVIARKGLTFRGEPEMSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C8</accession>
    <name>C7Q7C8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1291"/>
    <dbReference type="EnsemblBacteria" id="ACU70216">
        <property type="protein sequence ID" value="ACU70216"/>
        <property type="gene ID" value="Caci_1291"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1291"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="GSMPRID"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="26"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="40177" checksum="AADA12D5D71E81C4" modified="2009-10-13" version="1">MSNEPSETIVEDIALENTSPRGYLDVRDLKVHFPTDDGLVKSVDGITFQLERGKTLGIVGESGSGKSVTSLAIMGLHRSANEKKKKRGAQVSGEIWLDGQDLVTASSEEVRRLRGEKMAMIFQDPLSAMHPFYTVGAQIIEAYRVHNDVPKGVARKRAIELLELVGIPQPHTRVDDFPHQFSGGMRQRAMIAMALVCNPSLLIADEPTTALDVTVQAQILDLMRDLQREFNSALIIITHDLGVVAELADDIMVMYGGKAVEYGSAHDIFKAPEHPYTWGLLASMPRLDRERAARLTPIQGNPPSLINVPSGCAFHPRCPYGATETAGRSDTEIPLLAATAPGHLVRCHMDPARRREIYTEKIQGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7F4</accession>
    <name>C7Q7F4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gatA</name>
        <name evidence="9" type="ordered locus">Caci_1318</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785536.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1318"/>
    <dbReference type="EnsemblBacteria" id="ACU70242">
        <property type="protein sequence ID" value="ACU70242"/>
        <property type="gene ID" value="Caci_1318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1318"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_11"/>
    <dbReference type="OMA" id="EVSCPHF"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="502" mass="52847" checksum="F5502F39C49AF2B7" modified="2009-10-13" version="1" precursor="true">MSNRFDGELTRSTAAALAGAIRNGEVTATDVAQAHLDRIAKVDEKVHAFLHVDAEGALAKAAEVDAKLARGERLGPLAGVPLALKDVFTTKGVPTTCGSKILQGWVPPYDATVTRRLREADIVILGKTNMDEFAMGSSTENSAYGVTHNPWDLTRIPGGSGGGSSASLAAFEAPLAIGTDTGGSIRQPASVTGTVGVKPTYGGVSRYGLVAFSSSLDQGGPCARTVLDAALLHAVIAGHDPMDSTSIDLPVPDVVGAAKLANVEGMRIGVVKQFDGEGYQEGVRQRFHEAVQTLRDLGATVVEVDCPSFDYALPAYYLIAPSECSSNLARFDAMRYGLRVGDDGVNGVEEVMALTREAGFGPEVKRRIMLGTYALSSGYYDAYYGSAQQVRTLIMRDFDRAFADVDVLVSPTTPTTAFKIGERADDPMAMYLADLCTIPTNMAGNAGMSVPVGLAPEDGLPVGLQIIAPAMADDRLYRVGAAVEAAMTTKWGHPLIEEVPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7F5</accession>
    <name>C7Q7F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785537.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1319"/>
    <dbReference type="EnsemblBacteria" id="ACU70243">
        <property type="protein sequence ID" value="ACU70243"/>
        <property type="gene ID" value="Caci_1319"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1319"/>
    <dbReference type="HOGENOM" id="CLU_2664352_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="7756" checksum="058DBA288046FFB7" modified="2009-10-13" version="1" precursor="true">MSKKKNAAKARGTFGTLFAIGSSVTLAPVLARRFKEARVKGDKLALADAAVSAAALTVGVLQVLRSRRGAGKNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Q4</accession>
    <name>C7Q7Q4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="4" type="ordered locus">Caci_3340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3340"/>
    <dbReference type="EnsemblBacteria" id="ACU72247">
        <property type="protein sequence ID" value="ACU72247"/>
        <property type="gene ID" value="Caci_3340"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3340"/>
    <dbReference type="eggNOG" id="COG0682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013386_2_0_11"/>
    <dbReference type="OMA" id="TDVPWAI"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="33150" checksum="4ABB7728EB00DCD6" modified="2009-10-13" version="1">MTLAYVPSPSQGVWHLGPVPVRAYAMCILLGIVVAVVWTGRRWEARGGRREDVVDVAIWAVPFGLVGGRLYHVITDPELYFKAGEDPVKAFYIWDGGLGIWGAVALGAVGAWIGCRRKGIDLADFADALAPALALAQAIGRWGNYFNQELYGRPSGLPWAIRIDPSHRPPNTPNAVFYQPTFLYESIWDVAVALALVWIDRKWHPNRGRLFAIYVAAYTAGRAVVEALRDDHANRFLGLRLNDWVSLIVFLGALAYLWIRRDRRTLTGTGNSMQTAEAETAEAETAEAETAEGDSAPEGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W6</accession>
    <name>C7Q8W6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-fuconate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1458</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:22772"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:21291"/>
            <dbReference type="ChEBI" id="CHEBI:37448"/>
            <dbReference type="EC" id="4.2.1.68"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.2.1.68" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785675.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1458"/>
    <dbReference type="EnsemblBacteria" id="ACU70381">
        <property type="protein sequence ID" value="ACU70381"/>
        <property type="gene ID" value="Caci_1458"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1458"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_2_0_11"/>
    <dbReference type="OMA" id="YDTSVGW"/>
    <dbReference type="OrthoDB" id="743369at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050023">
        <property type="term" value="F:L-fuconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03324">
        <property type="entry name" value="rTSbeta_L-fuconate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034610">
        <property type="entry name" value="L-fuconate_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00111">
        <property type="entry name" value="L-fuconate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="7">
        <location>
            <begin position="199"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="47555" checksum="8055B3ED6FFA2B01" modified="2009-10-13" version="1">MSRIVGFETFDVRFPTSRELDGSDAMNPDPDYSAAYLILRTDAEDGLSGHGFTFTIGRGNDVQVAAIEALREHVLGRDVEEVCADPGIVNRALIGDSQLRWLGPEKGVMHMAIGAVVNAIWDLAAKRAGVPLWKLLADADPRWLVSQVDFRYLTDALTPEEALEMLRRGKDGAAARETSLRAEGYPAYTTSPGWLGYSDEKLTRLAHEAVAAGFTQIKLKVGADLADDVRRCRAARAAVGPDVRMAIDANQRWNVGEAIEWVKALAEFDVYWIEEPTSPDDVLGHAAIRGAVAPVKVATGEHVQNRIIFKQLLQAEAIDFVQLDAARVGGVNENLAILLLAAKFGVPVCPHAGGVGLCELVQHLSMFDFVALSGSRTDRVVEYVDHLHEHFVTPTVVTGGAYQTPTTPGFSAEMFPATLEAYSFPDGSFWRADRGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Y5</accession>
    <name>C7Q8Y5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787598.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3399"/>
    <dbReference type="EnsemblBacteria" id="ACU72305">
        <property type="protein sequence ID" value="ACU72305"/>
        <property type="gene ID" value="Caci_3399"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3399"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116681_1_2_11"/>
    <dbReference type="OMA" id="GWHVLET"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="29"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16296" checksum="E01E558AAA1478F7" modified="2009-10-13" version="1">MDPEVQSGRTSPVAEAAVETEAETVVIQVPADADYLPIIRSASAHVATKVGCTLSEVADLRLAVDEACGLLLRHTIRDRQSLTGAGDLVCRFVLDEVALRVVLSRQARNAAPPQSDEFGWTILSALVDDILWRVDGPTVHVEILKRRTGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q916</accession>
    <name>C7Q916_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787629.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3430"/>
    <dbReference type="EnsemblBacteria" id="ACU72336">
        <property type="protein sequence ID" value="ACU72336"/>
        <property type="gene ID" value="Caci_3430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3430"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2258663_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="10437" checksum="05473FA37E08E555" modified="2009-10-13" version="1">MGDDGSSALVEAVGRAELVERTEPVERTDLVAMLCGVVAEVCELPGCAPDDRFADLGVDSVRAAEAAAVLEDALGFGVPLEAVFAAGTPAGLAELLAKIDDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9U6</accession>
    <name>C7Q9U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.157" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7440"/>
    <dbReference type="EnsemblBacteria" id="ACU76265">
        <property type="protein sequence ID" value="ACU76265"/>
        <property type="gene ID" value="Caci_7440"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7440"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="FYDYSES"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="3">
        <location>
            <begin position="28"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="2">
        <location>
            <begin position="210"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="32944" checksum="AE009E648CA53110" modified="2009-10-13" version="1">MTDSVSCSATDSATDSATDPVPHDLRLIGVVGCGQMGSGIAEVCARAGFDVVVTETTTAAATAGRTRIEASLTRAADRGKITDVERKEALHRITVTADFDRLADRDLVIEAVAENEALKLDVFTRLDRTVRSRDAILATNTSSIPVIRLATATSRPDHVIGLHFFNPVPVLKLVELIPCLATSPETEARTTTFATRSLAKHPIRSRDQAGFIVNALLIPYLLSATRMLESGMASRQDIDQGMVLGCAYPLGPLALADLIGLDTVKAIAESMYAEFKDPHHSPPPLLTRMVEAGHLGRKTGRGFHSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA03</accession>
    <name>C7QA03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1478</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785695.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1478"/>
    <dbReference type="EnsemblBacteria" id="ACU70401">
        <property type="protein sequence ID" value="ACU70401"/>
        <property type="gene ID" value="Caci_1478"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1478"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040537_0_0_11"/>
    <dbReference type="OMA" id="YFYMASF"/>
    <dbReference type="OrthoDB" id="1217595at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="221"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="40844" checksum="DABC80F1525D63CB" modified="2009-10-13" version="1">MSLISDPSRAESSAEAGEATEVISRGVRGRMAVWGAAHAVDDMYQGLVPASVPYFVLERHYSYLAASGLTLAATLGSALPQPLVGLAVDRWRLPRLAAVGVAVAGTGLGLSGLAGPYALVWLCILISGFGVAMFHPAAGRSAREAAGDSAAAMSVFAAGGSVGFFLAPVLATPALNAWGVGATALFIPPAWLIALVLLKKRAGTRPSHAAASGGQDRWGPFAALTGIEVVRSAAFFGINTFIELYWIKHLHASRTMAGAALACFLIGGVAGTLLGGRIADRVGMVRTVQLGGALTIPMLLALRFSPGAVAPLAFAVLTGLALNIPFAVLVKLGQDYLPGRPGTAAGVTLGLGVSAGGLMAPVFGLIAEHRGPQGVLTALCAVPIAGIVLGFLLREPQKTDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA23</accession>
    <name>C7QA23_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavin-binding monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1498"/>
    <dbReference type="EnsemblBacteria" id="ACU70421">
        <property type="protein sequence ID" value="ACU70421"/>
        <property type="gene ID" value="Caci_1498"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1498"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_7_1_11"/>
    <dbReference type="OMA" id="HEICAYL"/>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047091">
        <property type="term" value="F:L-lysine 6-monooxygenase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="524" mass="58132" checksum="BA39C045640EC81A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV9</accession>
    <name>C7QAV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794161.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5573"/>
    <dbReference type="EnsemblBacteria" id="ACU74432">
        <property type="protein sequence ID" value="ACU74432"/>
        <property type="gene ID" value="Caci_5573"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5573"/>
    <dbReference type="eggNOG" id="ENOG5031S8F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111671_1_1_11"/>
    <dbReference type="OMA" id="YVAMESF"/>
    <dbReference type="OrthoDB" id="1942143at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021607">
        <property type="entry name" value="DUF3224"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023159">
        <property type="entry name" value="SO1590-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11528">
        <property type="entry name" value="DUF3224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159238">
        <property type="entry name" value="SSF159238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="15663" checksum="ED3662135FF1BA9F" modified="2009-10-13" version="1">MRTEGTFTVISFAPAAVEPSLEIVTATPTGVATMEKAFEGGIAGRSATLFTSAYDQERGAGTYVALESFEGRLGEFGGTFNFVHSATTAGADRSDEYFLIVPGSGTGELVGVTGTGGIEIDAEGVHRIWFDYEIAGEIAGSQGPDVTAGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW0</accession>
    <name>C7QAW0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="14" type="ordered locus">Caci_5574</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794162.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5574"/>
    <dbReference type="EnsemblBacteria" id="ACU74433">
        <property type="protein sequence ID" value="ACU74433"/>
        <property type="gene ID" value="Caci_5574"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5574"/>
    <dbReference type="eggNOG" id="COG0018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_5_1_11"/>
    <dbReference type="OMA" id="HHIGDWG"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="13">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="12">
        <location>
            <begin position="503"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU74433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="619" mass="66417" checksum="20C95A1F7CC87747" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBL2</accession>
    <name>C7QBL2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="9">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_1668</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 9">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1668"/>
    <dbReference type="EnsemblBacteria" id="ACU70589">
        <property type="protein sequence ID" value="ACU70589"/>
        <property type="gene ID" value="Caci_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1668"/>
    <dbReference type="eggNOG" id="COG0843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011899_7_1_11"/>
    <dbReference type="OMA" id="WAMMSIG"/>
    <dbReference type="OrthoDB" id="316745at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="11">
        <location>
            <begin position="26"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="551"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="64173" checksum="5D1D0FC721C58288" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBM1</accession>
    <name>C7QBM1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome aa3 subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1677</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785892.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1677"/>
    <dbReference type="EnsemblBacteria" id="ACU70598">
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        <property type="gene ID" value="Caci_1677"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1677"/>
    <dbReference type="eggNOG" id="COG1845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044071_1_1_11"/>
    <dbReference type="OMA" id="ASGMLWM"/>
    <dbReference type="OrthoDB" id="1502742at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="9">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="23099" checksum="BFBE0C90618274C1" modified="2009-10-13" version="1">MAAVATATATTQAGQAHRLPNRPNLVSVGTIVWLSSELMFFAALFAMYFTIRSVHGSQYFVQQAKHLNMWLAGPNTTILVLSSVTCQMGVFAAERGDVRRLRFWFMITFVMGSIFVAGQVWEYSALVKENLSIGANAWTSVFYLTTGFHGMHVTGGLLAFLLVLGRTYLAKRFTHDQATSAIVVSYYWHFVDVVWLGLFFVIYIMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBN4</accession>
    <name>C7QBN4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">Caci_1690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785905.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1690"/>
    <dbReference type="MEROPS" id="M24.A06"/>
    <dbReference type="EnsemblBacteria" id="ACU70611">
        <property type="protein sequence ID" value="ACU70611"/>
        <property type="gene ID" value="Caci_1690"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1690"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_2_1_11"/>
    <dbReference type="OMA" id="GDHAYTF"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="45"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="31130" checksum="E59956ADFDEACACE" modified="2009-10-13" version="1">MATLVPGTVSPTLPVPAAIKRPEYVGRKGPRPYTGGEVQDAETVEKMRTASRIAADALVETGRAAKPGVTTDELDRIGHEYLLDHRAYPSTLGYKGYPKSMCTSVNEVICHGIPDTTVLADGDIVNVDITAYIGGVHGDTNATFEVGTVDEESHLLVERTREALDRAIKAVRPGRQINVIGRVIESYAKRFGYGVVRDFTGHGISTAFHTGLIIPHFDDPYATLVMQPGMTFTIEPMLTLGTADYEMWPDKWTAVTRDRKRTAQFEHTMVVTNDGVEVLTLPSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW7</accession>
    <name>C7QBW7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792315.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3684"/>
    <dbReference type="EnsemblBacteria" id="ACU72586">
        <property type="protein sequence ID" value="ACU72586"/>
        <property type="gene ID" value="Caci_3684"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3684"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_3_11"/>
    <dbReference type="OMA" id="EHNKQIF"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="12"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="34039" checksum="B60DB528B91BEB41" modified="2009-10-13" version="1" precursor="true">MTSKALTVPMAVMGTWAWGDSGKAGEGYFGTQLSESGLREVVDKAQANGFTLWDTAAVYGAGRSETVLAQALMGYDRSEYQLSTKFTPQMAGDGGDPVADMLEQSLQRLSTDYVDLYWIHNPADVARWTPSLIPLLKSGKIKHVGVSNHSMEQIAAADRILGEAGFRVEAVQNHYSLLYRSSERAGILEHCRENDVRFFSYMVLEQGALTGKYSPANPLPEGSSRAGVYNGILPQLQALTHRMGTLGEDRGASAADIATAWAIAKGTTPIVGVTKAGHIDGLTRAGGIELADEEIAELEALADAAGVDTRGWWEQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC33</accession>
    <name>C7QC33_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792381.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3750"/>
    <dbReference type="EnsemblBacteria" id="ACU72652">
        <property type="protein sequence ID" value="ACU72652"/>
        <property type="gene ID" value="Caci_3750"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3750"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_1_1_11"/>
    <dbReference type="OMA" id="ENDHYDA"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="44"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="428"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="737" mass="76817" checksum="108559D769A31C01" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC36</accession>
    <name>C7QC36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792384.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3753"/>
    <dbReference type="EnsemblBacteria" id="ACU72655">
        <property type="protein sequence ID" value="ACU72655"/>
        <property type="gene ID" value="Caci_3753"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3753"/>
    <dbReference type="HOGENOM" id="CLU_2618038_0_0_11"/>
    <dbReference type="OMA" id="ACIPEQG"/>
    <dbReference type="OrthoDB" id="2104414at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="7281" checksum="B9671A87A35D0EC2" modified="2009-10-13" version="1">MKSIISRLSDKALSALLREETAGACIPEQGKPCTNSYCSSSGAWYTCSSTYSCTGACSCTPHYTQNRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC52</accession>
    <name>C7QC52_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794229.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5641"/>
    <dbReference type="EnsemblBacteria" id="ACU74500">
        <property type="protein sequence ID" value="ACU74500"/>
        <property type="gene ID" value="Caci_5641"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5641"/>
    <dbReference type="eggNOG" id="ENOG5033HWY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177682_0_0_11"/>
    <dbReference type="OMA" id="RWATRAM"/>
    <dbReference type="OrthoDB" id="1964354at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="10336" checksum="40A1DD0829D9935E" modified="2009-10-13" version="1">MVGDEQPDLGEIEARFIAVVEGRLSRDDADRWAARWLFDDTLAWDATECWALGLLAGIDLRHGPAGDFLHDDSQVRAWLQELRERSNKRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM2</accession>
    <name>C7QCM2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter, periplasmic phosphate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796210.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7661"/>
    <dbReference type="EnsemblBacteria" id="ACU76485">
        <property type="protein sequence ID" value="ACU76485"/>
        <property type="gene ID" value="Caci_7661"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7661"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034528_3_0_11"/>
    <dbReference type="OrthoDB" id="1222928at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981544" evidence="3">
        <location>
            <begin position="38"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="4">
        <location>
            <begin position="33"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="605" mass="61196" checksum="8003440A9CCB795A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR9</accession>
    <name>C7QDR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794422.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5835"/>
    <dbReference type="EnsemblBacteria" id="ACU74693">
        <property type="protein sequence ID" value="ACU74693"/>
        <property type="gene ID" value="Caci_5835"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5835"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_8_11"/>
    <dbReference type="OMA" id="QEILWRM"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15012" checksum="D0B0BA0B5415DF00" modified="2009-10-13" version="1" precursor="true">MKTVSEPSAGSALLALQRATHATLQTLASELVDLDLTPSETNALANLADGRGRTVSELGAAIGTKPTTLTGVLDRLERRGQITRGVRSGDRRSVLIELTPSGQSTADAISATIAGLEQRALADLGPEKVAAFHEVLRALTEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE70</accession>
    <name>C7QE70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP/GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7834</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7834"/>
    <dbReference type="EnsemblBacteria" id="ACU76658">
        <property type="protein sequence ID" value="ACU76658"/>
        <property type="gene ID" value="Caci_7834"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7834"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023036_0_0_11"/>
    <dbReference type="OMA" id="RNPYAYR"/>
    <dbReference type="OrthoDB" id="342373at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018929">
        <property type="entry name" value="DUF2510"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10708">
        <property type="entry name" value="DUF2510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2510" evidence="4">
        <location>
            <begin position="13"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="DUF87" evidence="3">
        <location>
            <begin position="266"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="664" mass="71807" checksum="F92BE2E95D7403CB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE88</accession>
    <name>C7QE88_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage shock protein A, PspA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1859"/>
    <dbReference type="EnsemblBacteria" id="ACU70779">
        <property type="protein sequence ID" value="ACU70779"/>
        <property type="gene ID" value="Caci_1859"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1859"/>
    <dbReference type="eggNOG" id="COG1842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056466_1_0_11"/>
    <dbReference type="OMA" id="MIFRAKA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="44"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="29644" checksum="502D8061FD06A233" modified="2009-10-13" version="1">MKRMKLIFQAKANKALDKYEDPRETLDLSYQKQLELLQKVRRGVADVATSRKRLELQMKQLQDQADKHETQARRALEVGREDLAREALSRRGGIQQQITDLQTQYAALQGEEEKLTRASQSLQAKVDAFRTKKETLKATYTAAEATTRIGEAFSGISEEMSDVGMAIQRAEDKTLQLQARGSAIDELLASGALNDPTGMAKDDITTELERLSSGSDVDNQLEAMKRELTGGPSAKQIEAGKTVGNASDQGVSDAEEVSARGQDREGEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QED0</accession>
    <name>C7QED0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase-binding protein RbpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbpA</name>
        <name evidence="3" type="ordered locus">Caci_1901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Bind 1 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with the RNAP catalytic core and with free principal sigma factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase-binding protein RbpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1901"/>
    <dbReference type="EnsemblBacteria" id="ACU70821">
        <property type="protein sequence ID" value="ACU70821"/>
        <property type="gene ID" value="Caci_1901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1901"/>
    <dbReference type="eggNOG" id="ENOG5032TBE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134276_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001000">
        <property type="term" value="F:bacterial-type RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01483">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038638">
        <property type="entry name" value="RbpA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025182">
        <property type="entry name" value="RNApol-bd_RbpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13397">
        <property type="entry name" value="RbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="11835" checksum="B4F1ED4F711D3D2B" modified="2009-10-13" version="1">MSRSSGIRGSRIGAGPMGESDRGNSVERVVVTFWCADGHSTPAVFAAEAVVPETWECQTCGQPAGLDRDNPPPAALAAPFKTHLAYVRERRSDADGEKLLAEALAKLRQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEH1</accession>
    <name>C7QEH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase BadF/BadG/BcrA/BcrD type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786155.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1942"/>
    <dbReference type="EnsemblBacteria" id="ACU70862">
        <property type="protein sequence ID" value="ACU70862"/>
        <property type="gene ID" value="Caci_1942"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1942"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016274_3_0_11"/>
    <dbReference type="OMA" id="RDGMGWL"/>
    <dbReference type="OrthoDB" id="1589192at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="8"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="344" mass="34694" checksum="CD62F48AAF33C9E8" modified="2009-10-13" version="1">MTDEALVLGLDVGGTSTRVLAVTPHGLRRGAGRASGGNPTGLGPERAAAALAEAVAQALTGLDPADVRHVVLGLAGGGALPSGEDMPGGEAFTRVWDQTGIRCPIEYEPDALIAFAAGTAAAEGSLLLSGTGAVAIAVKDRTMAARADGHGWLLGDRGSGFWLGRQAVLAAMAELDGEGPATVLTDLVIESLRLRGSSPVAGPASGADAGADTPLTAREMVAAVMSEPPTALARLAPLLTAACEGGDAVAKAIADRAVEHLAATLTTVRGPDATSPIVLAGSVLTNPTPVAERVRRMLRERWPDAEVSRALDGAAAAAWLALARIGPMPSPDVRERLFSIPTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEV3</accession>
    <name>C7QEV3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3998</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792602.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3998"/>
    <dbReference type="EnsemblBacteria" id="ACU72873">
        <property type="protein sequence ID" value="ACU72873"/>
        <property type="gene ID" value="Caci_3998"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3998"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_12_11"/>
    <dbReference type="OMA" id="IREVCTL"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21899" checksum="E23362BB67AB78EC" modified="2009-10-13" version="1">MPRISPERRAAKRGDIIAAARRCFSRDGFHQTSMPEIAAEAGLSAGAPYRYFASKEEIILAIASDAFRLVFEPVQRLAEATDAPTVADLVAAALRTIEQDTVTDAAGRMVPVEELLRCAVQTWSEILRSEEVRDGAVKGFEGVHRSIAEALRRGQAVGSMPATVDADLAARTVMGLLHGMLLQRVAFGAADAAGLADGVQAVLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF30</accession>
    <name>C7QF30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794517.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5930"/>
    <dbReference type="EnsemblBacteria" id="ACU74788">
        <property type="protein sequence ID" value="ACU74788"/>
        <property type="gene ID" value="Caci_5930"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5930"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058821_2_0_11"/>
    <dbReference type="OMA" id="NTRMFKY"/>
    <dbReference type="OrthoDB" id="1488051at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="25088" checksum="F1A76436FDA9DDE4" modified="2009-10-13" version="1">MTIDVVDESVPADGTRGQHVLDLLDKAINTQTPLVRKNIARARQKNPEAPPARVIRNLERMYVSALTGSGAAVGGTAAAPGVGTGVALALSAGEALSSLELSVLFALSIAEVHGVRIDEIERRRTIVMGIMLGGSGSSTIAKISERTGQHWGRQIVAKVPAESLRQINKVLGRNFVTKYGTKQGVIVLGRVAPFGIGAVIGGGANAALATLSVRAGRRAFGPPPEAWPESEHSAAAEPISAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF96</accession>
    <name>C7QF96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7849</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7849"/>
    <dbReference type="EnsemblBacteria" id="ACU76673">
        <property type="protein sequence ID" value="ACU76673"/>
        <property type="gene ID" value="Caci_7849"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7849"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="TALFMEN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="485" mass="49904" checksum="0EB7B0E1DF133673" modified="2009-10-13" version="1">MPESTHRRRYLILVICCMSLFIVGIDNTAVNVALPSIQRDLNAPVSGLQWTIDAYTLTLASLLILAGSLGDRLGRRRVFMTGTSLFVVGSALCALAPSLGALVGARALQGVGGAMMNPVAMSIITNVFTDNKDRAKAIGMWSAAFGVSMAAGPVVGGLLLSATSWRSIFWVNVPVGLAAVVLTRVFVPESKAPTARRFDPVGQVLGIAFLAGVTYAIIEAPHVGWVSAQTVAVFVAAIAAAVGFVAYELRREQPLIDPRFFRSVPFSGATLMAISGFLALSGFLFMNTLYLQDALGYSALKAGLLTLPIAVASVIVGPRAGRWVANHGPRAPLIAAGVLLAVSALLLTGLSATTPVALLLVAYAILGLGFGTLNPPITNTAVSGMPRAQAGVAAAVASTSRQVGQTLGVAIIGSVVVARATGPARTGLPAASHAGWWILFGCGLTVFVLGMLTTGKRAAATAASTAARLTEPAEPTTEPGIPALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFI3</accession>
    <name>C7QFI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UBA/ThiF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7937"/>
    <dbReference type="EnsemblBacteria" id="ACU76760">
        <property type="protein sequence ID" value="ACU76760"/>
        <property type="gene ID" value="Caci_7937"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7937"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042635_0_0_11"/>
    <dbReference type="OMA" id="SGTPHLY"/>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="43754" checksum="2277B0B6014FB331" modified="2009-10-13" version="1">MRPVLKAGLRRLWRPGGSLQVGVTPGRSLLLNGLSPTATAFLGALDGHRDIAGLLTLAEEIGLSGAHATTLLDMLARAGFLDDAAYDPGPALRALDVAEADRLAPDMAALALGYLVPGGAVRAMTRRRMAVVAVYGCGRVGASVAHMLASAGIGCVVPIDSGRARAADAAPAGFRNPRGLSHRDEREVPAPRRGRGRGSRAADSAAADTVSATTNTADPQPDDESNLAAPPPRRQDLVRTLIRTSAPSTRTTMPANRQRPDVAVLAPIADGYPAQAATLQSDGVPHVPAEVHETTGVLGPFVQPGRTSCLRCRDLYRTARDPGWPRAMVPFGGVDAVPAAEDRACDVTMATHLAVQTALHVLAFVEGDPPPTMNATLELAPPFGAQTRHERPPHPDCGCLVDLTEEAPAGSYLSFRAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFM6</accession>
    <name>C7QFM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Curculin domain protein (Mannose-binding) lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784260.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0010"/>
    <dbReference type="EnsemblBacteria" id="ACU68965">
        <property type="protein sequence ID" value="ACU68965"/>
        <property type="gene ID" value="Caci_0010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0010"/>
    <dbReference type="eggNOG" id="ENOG502ZHTU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137596_0_0_11"/>
    <dbReference type="OMA" id="ESHTARS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
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        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="SSF51110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982826" evidence="1">
        <location>
            <begin position="30"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="27"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="14565" checksum="54B6E6D8B4F251B7" modified="2009-10-13" version="1" precursor="true">MVKRTIGAIAGAAALAAALSVAGTGTALAATGGDHLNKGDTMYANDDIHNPAGTKLVFQPDGNLVEYRYDGHVCWATGTNGRGGTRVTYQNDGNLVMYASTDDSRPIWASGTSGDNGLNVNINARGEIWVGYDQLTNACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU2</accession>
    <name>C7QFU2_CATAD</name>
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        <submittedName>
            <fullName evidence="3">Protease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1999"/>
    <dbReference type="EnsemblBacteria" id="ACU70919">
        <property type="protein sequence ID" value="ACU70919"/>
        <property type="gene ID" value="Caci_1999"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1999"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403196_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
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        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983105" evidence="1">
        <location>
            <begin position="37"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="83"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="682" mass="68867" checksum="AC4767D466A34508" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG15</accession>
    <name>C7QG15_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786285.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2073"/>
    <dbReference type="EnsemblBacteria" id="ACU70992">
        <property type="protein sequence ID" value="ACU70992"/>
        <property type="gene ID" value="Caci_2073"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2073"/>
    <dbReference type="eggNOG" id="COG4485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_310306_0_0_11"/>
    <dbReference type="OMA" id="REGWHAT"/>
    <dbReference type="OrthoDB" id="754519at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09586">
        <property type="entry name" value="YfhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1047" mass="109707" checksum="A3BD7AE0E18DF276" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG49</accession>
    <name>C7QG49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase A24A prepilin type IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4026"/>
    <dbReference type="EnsemblBacteria" id="ACU72894">
        <property type="protein sequence ID" value="ACU72894"/>
        <property type="gene ID" value="Caci_4026"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4026"/>
    <dbReference type="eggNOG" id="COG1989">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057101_2_1_11"/>
    <dbReference type="OMA" id="WIDHFTL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014032">
        <property type="entry name" value="Peptidase_A24A_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00864">
        <property type="entry name" value="PREPILNPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="4">
        <location>
            <begin position="80"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="22707" checksum="5DB90B9FD4C4F48C" modified="2009-10-13" version="1">MSHLTTDAPAIALGAAVGTVGGLYAPRAVRLAIAKGPDGDSSADGLPRVVAALIVTSAAVAGALVGARFGLQARVPAYLYLAAITPALAAVDATTHILPNRIVLPAYPLTVALLAFAAWRASGPGALWRALAAGALLYVIFLAVALVAPPDSLGWGDVKLVGLLGLCLGFLGWKTTWRGMMLAFGLAALCVMVRLLVRHEQRSHALPLGPALLLGSLAAVIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG57</accession>
    <name>C7QG57_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4034"/>
    <dbReference type="EnsemblBacteria" id="ACU72902">
        <property type="protein sequence ID" value="ACU72902"/>
        <property type="gene ID" value="Caci_4034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4034"/>
    <dbReference type="HOGENOM" id="CLU_1944843_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="13477" checksum="D76DB7760E0378BB" modified="2009-10-13" version="1" precursor="true">MRQAKEGTRMPTQARTSQRPSRCVLLVGPAIAAALALLVAFVAAVLEPSASAWSLLRLVALLAAGWIPIRLAREAAAYCAEDAGRPKDRAVRVANRSSGVLDVPAVSTHSFGRALAPGREALPSGSTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA8</accession>
    <name>C7QGA8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792682.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4088"/>
    <dbReference type="EnsemblBacteria" id="ACU72953">
        <property type="protein sequence ID" value="ACU72953"/>
        <property type="gene ID" value="Caci_4088"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4088"/>
    <dbReference type="HOGENOM" id="CLU_2492158_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="9195" checksum="0B61C1EF656889FF" modified="2009-10-13" version="1">MSAGAEICQGRPALCPRCEHDLIDDPAGPWCRTCHTAQTGARRHGPCPIPATATGNTPRTKGLRLCRAHARRLVDRGGPDAVVRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM6</accession>
    <name>C7QGM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794635.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6049"/>
    <dbReference type="EnsemblBacteria" id="ACU74906">
        <property type="protein sequence ID" value="ACU74906"/>
        <property type="gene ID" value="Caci_6049"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6049"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="DVWVPPD"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="24042" checksum="168B201B487B63F3" modified="2009-10-13" version="1">MIRVLLADDQALVRAGFRALLEVQDGIEVAGEAADGAEAHRLAAELAPDVILMDIRMPGTDGLEATRLITADEKLSGVRILILTTFELDEYVFEAIRAGASGFLLKDTEPADLLRGLRAVAAGEALLAPSVTRRLIAEFAVRSKRTGPNPAAEQIKALTEREREVLALVAAGLSNEEIADRLVLSPLTAKTHVSRSMVKLGARDRAQLVVLAYESGLARPGWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM8</accession>
    <name>C7QGM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794637.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6051"/>
    <dbReference type="EnsemblBacteria" id="ACU74908">
        <property type="protein sequence ID" value="ACU74908"/>
        <property type="gene ID" value="Caci_6051"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6051"/>
    <dbReference type="eggNOG" id="ENOG5031FUG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1517110_0_0_11"/>
    <dbReference type="OMA" id="FGMIACA"/>
    <dbReference type="OrthoDB" id="1516231at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20719" checksum="77F6D287CFCB6299" modified="2009-10-13" version="1">MDSDQSDHHLRRIRLWLALFITGLVLSGVTAFPLETETRWLSAWLHHLPAPGALTAWIDRTHEGLQQTNAEYPFISYGTDWLAFGHLTIAVAFYGPWRDPVRNKWVVQFGMIACAGVIPLALICGPIRGIPFGWSLVDMSFGVFGALPLIPVWRHIKVLESGGPVRTPPGVPAPGAQPPLDGYPRPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGT0</accession>
    <name>C7QGT0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polypeptide-transport-associated domain protein FtsQ-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794689.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6105"/>
    <dbReference type="EnsemblBacteria" id="ACU74960">
        <property type="protein sequence ID" value="ACU74960"/>
        <property type="gene ID" value="Caci_6105"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6105"/>
    <dbReference type="eggNOG" id="COG1589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047677_1_0_11"/>
    <dbReference type="OMA" id="SWPHGIG"/>
    <dbReference type="OrthoDB" id="1270665at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="57"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="28014" checksum="014333680F54C191" modified="2009-10-13" version="1">MNATGAGHPRVSRVLVERYLDRLRRRRRWRRLSVTITVFLALLALTGYSILWHTKVFDVRTTTVSGVKVLSRQQVLAAAAIPAHAPVAAVDTAAAKARLMALPRVKDAWVERSLPHTVSIGIVERTPAAALPQPDGSFQIVDADGVAFDTAASASAIPAHVPVIHLEQFADPGPEAKAARAATVAGALAALRALPPPVLSRVLTVSATGPYAITVTLTPSTKKQHSVTVAWGGPDQPVLKARILAALIGNDAAHYDLSAPAAPAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGX4</accession>
    <name>C7QGX4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796549.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8001"/>
    <dbReference type="EnsemblBacteria" id="ACU76824">
        <property type="protein sequence ID" value="ACU76824"/>
        <property type="gene ID" value="Caci_8001"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8001"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029927_6_0_11"/>
    <dbReference type="OMA" id="LYAMEAR"/>
    <dbReference type="OrthoDB" id="710201at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="53728" checksum="500D51B99BC0D887" modified="2009-10-13" version="1">MTGKPPNELLNSWFQRSGWSKGELARLVNKRARQLGAAHVSTDTSRVRRWLDGEHPRDPAPRILVELFSERFGTVITHAELGLREPAAPPATSGVDLPWAGRRSIELLGDFARSDLMLNRRGFLGTSLSLSAGPSLIEPMKRWLSPVPEQHSVNGRLPGRVTAEEMDRLEETTRLFRGWDAQCGGGLRRMAVVGQLHEVTELLRDNYAPALSERLFRTAAELALLAGWMAYDIGMQPSAQRYFVLALHAAREAGDTPLGALVLATMSRQMIHINRPQDALELVHLAQYGSHGTTTARVQSLLAAMEARAYANLGDSDNCRRAVAAAEDLFPGDFPAGQDRAERGSNGAGGDRTRGGDPSWIAFFTEAELYGENGHSFRDLAYRYPQLTEQAAKNIDRAVELLSADDSYLRSRALNVVGMATVRLQQREPEAAVAYLHGGAELVQRLRSKRVEDRLRTTAGNLFARYPDVRSVREVHERTLAVLPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHB8</accession>
    <name>C7QHB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0102"/>
    <dbReference type="EnsemblBacteria" id="ACU69057">
        <property type="protein sequence ID" value="ACU69057"/>
        <property type="gene ID" value="Caci_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0102"/>
    <dbReference type="eggNOG" id="ENOG502ZMWM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2407864_0_0_11"/>
    <dbReference type="OMA" id="VWFLFAN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="10175" checksum="C9CD31FCF1A00933" modified="2009-10-13" version="1">MTTQAPQPPPASQPPRTAADKAQRSRMIGAIVIAVVAIWFILANTRKASITFWIVTVTSPMWLTLAGTFLAGMLTSLLLTRTRTRKRQKQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHM9</accession>
    <name>C7QHM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal small subunit Rsm22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786347.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2135"/>
    <dbReference type="EnsemblBacteria" id="ACU71054">
        <property type="protein sequence ID" value="ACU71054"/>
        <property type="gene ID" value="Caci_2135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2135"/>
    <dbReference type="eggNOG" id="COG5459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072591_0_0_11"/>
    <dbReference type="OMA" id="SKHAICR"/>
    <dbReference type="OrthoDB" id="1345405at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35597" checksum="44E48BE370C691A6" modified="2009-10-13" version="1">MDLPTDLAAALDAATADLPLRELESSVDRLIARYRTPGRADRPILSGHIDAAAYAAYRMPATWGAVRAALAATAERRPGWAPQSLVDVGGGTGAAAWAAATVFGDSLKEVTVLDQVTEALELGRGLARNAFSGALRHAEWRKVRFPAEVPGADLVTVSYVLSELAPDAQQALVRASAAGAETIAILEPGTPDGYQRIIAARDVLIDMGLRVAAPCPHSETCPLLATGDWCHFASRIHRTPLHRRLKGADLQYEDEKFAYVVATRTPVGASPARILRHPQTRKGLVMMQLCQPDGTVAQTLVSKRQGDVYRAARDADWGDEWPVLGSAQQPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHS2</accession>
    <name>C7QHS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">34 kDa antigenic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786390.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2178"/>
    <dbReference type="EnsemblBacteria" id="ACU71097">
        <property type="protein sequence ID" value="ACU71097"/>
        <property type="gene ID" value="Caci_2178"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2178"/>
    <dbReference type="HOGENOM" id="CLU_1944841_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035166">
        <property type="entry name" value="DUF5336"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17270">
        <property type="entry name" value="DUF5336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="13539" checksum="BF783B2D57E8F17D" modified="2009-10-13" version="1" precursor="true">MAVTVPLGKMLYLCVAALGVINLFLGYVSAGDGDSMNLYKVGVAIYTLAPTMFFLAGLVAVRGFLPRERAPGALPAMISSAIFVTLVLSAISSDGAGDLQTLFLVFGAVQFVIAWLAYLFDSGVIAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHX5</accession>
    <name>C7QHX5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MPAB_Lcp_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792749.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4156"/>
    <dbReference type="EnsemblBacteria" id="ACU73020">
        <property type="protein sequence ID" value="ACU73020"/>
        <property type="gene ID" value="Caci_4156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4156"/>
    <dbReference type="eggNOG" id="COG3662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039076_1_0_11"/>
    <dbReference type="OMA" id="LGRHMGI"/>
    <dbReference type="OrthoDB" id="1462690at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="entry name" value="PTHR36124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPAB_Lcp_cat" evidence="1">
        <location>
            <begin position="63"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="31889" checksum="4BEDA112073B695B" modified="2009-10-13" version="1">MRNRDLDRLTYLRTLDPVGDHEEIYRTVAQFEFGWETMLGLNLAFYRTFGIPAIAELLYSTGEMTERTRKRADDTGLLMYELITHGLEAERGRAAVKRLNQIHRRFTIGADDYRYVLATFVVVPTRWIDRSGWRALCCHERTATVEFYRRLGELMHVTDIPASYAGFEHVLDTYEAEHFAHTAAAEALMAATRGLFAGRLPERLKGLAGPVADTLLSPPLREAVGAPTPALPVRLLVSGLIRLRASAEAWKAPRTEPYITLGTAHSYPEGYQVQELGPETVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHZ0</accession>
    <name>C7QHZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792764.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4171"/>
    <dbReference type="EnsemblBacteria" id="ACU73035">
        <property type="protein sequence ID" value="ACU73035"/>
        <property type="gene ID" value="Caci_4171"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4171"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="REYAMLD"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="36"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="7">
        <location>
            <begin position="276"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="36736" checksum="62CFF67EF39438A5" modified="2009-10-13" version="1">MTASNDRHELPEPHDLHDLEAQAARPRRQYGHDAHIVCDNLVRIYQTEGVEVQALQGLDLLVDRGDLVAVVGASGSGKSTLLNILSGLDTPTAGGARVAGCDLLAMKAKDRLRYRREVVGFVWQQTGRNLFSHLDALDNVMLPMSYAGTRGAAAERKAGELLDLLGVGHARDRRPAGLSGGEQQRVAIAVALANTPDVLFADEPTGELDSATAHQVFEALRTANRELGVTVVVVTHDADVAGQVRRTVAIRDGKTSSETVRAVAVDEDGAERHVAEEYVMLDRAGRMQLPREYVERLQMRDRVRVALDEDHVSVWPAADAGNDGDAGDEREAREPVPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI64</accession>
    <name>C7QI64_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792838.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4245"/>
    <dbReference type="EnsemblBacteria" id="ACU73109">
        <property type="protein sequence ID" value="ACU73109"/>
        <property type="gene ID" value="Caci_4245"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4245"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_1_2_11"/>
    <dbReference type="OMA" id="FWPRYPG"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="42213" checksum="31F4354A3C9DFFD1" modified="2009-10-13" version="1">MTDVVVIGAGQAGLSSAYHLHRAGFAPDTGYVVLDGDRAPGGAWQHRWPSLRMETVNGIFDLPGMAFEPPSPQEQASVAVPRYFAQYEERFQLAVRRPAAVSAVRSGPDDRLLVRTDTASGAQTWAARAVINATGTWNKPFWPYYPGRETFRGRQLHAATYPGPQEFAGKRVVVVGGGITAIQLLAELAEAGATTTWVTRRPPVFREEPFTREYGREVVAMVDRRVRAGLVPQSVVSVTGLPVTEAIREAQRSGVLQRLPMFDRITPEGIAWDAPDATAPADAARIADPIDTASDENTENTASLGAPPRSVAADVILWCTGWRAALDHLTPLHLRAPGGGITMDGTRVVLEPRLHLVGYGPSASTVGANRAGREAVRDIRRLLAQPAPAGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIP6</accession>
    <name>C7QIP6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796671.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8123"/>
    <dbReference type="EnsemblBacteria" id="ACU76946">
        <property type="protein sequence ID" value="ACU76946"/>
        <property type="gene ID" value="Caci_8123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8123"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_6_0_11"/>
    <dbReference type="OMA" id="GPCANKV"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="67" mass="7486" checksum="6DF5E42492A3F067" modified="2009-10-13" version="1">MAQGTVKWFNAEKGYGFIAVDGGSDVFVHYSAIQMDGYRSLEENQRVEFEISQGQKGPQADMVRVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ1</accession>
    <name>C7QIZ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8218"/>
    <dbReference type="EnsemblBacteria" id="ACU77041">
        <property type="protein sequence ID" value="ACU77041"/>
        <property type="gene ID" value="Caci_8218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8218"/>
    <dbReference type="HOGENOM" id="CLU_640466_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="44184" checksum="DE63836E96E9D28D" modified="2009-10-13" version="1">MTENSDLLVHDMIGRLFEEPEPMHRTDLADGAIAQGMAVTRRRGFAVAGATLSVLAVVAGATALAGGGTASGGGDWSIATGTGNISPQAYEDSAPTYSDRQREIAAELPGTIGPLLPQGVKVVPDRMSAGGDTSMLTGDYGQGVEVSSGGKNFAVRFDPTDATGYADAFARVSATPVAVAGGVIRVAVVPQGTESSFANGFTAWYEFKPTDAVKAPFRFYIYGDGQNTPIDATAFQKMIEAPGFGKLQHLLDPSVPASSAAVRLRYSIEAKINTEAKTILPAGFRLKLSPGAPGALELVGPDGVDTLEWFAIAGAHDQISCPAGSLCYTAHSGAQFKQVGPDGKARLGAYAGWTGTSKDSSIVLNVFGKPETGTSVEPAQLGKPVETAPQGSGLTPQQARAIIQAPGASKVITDVQRLVSMADLQQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ56</accession>
    <name>C7QJ56_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="9" type="ordered locus">Caci_0245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784493.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0245"/>
    <dbReference type="EnsemblBacteria" id="ACU69198">
        <property type="protein sequence ID" value="ACU69198"/>
        <property type="gene ID" value="Caci_0245"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0245"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_0_1_11"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="PTHR11778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="173"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="46467" checksum="7B08D55AD1F28371" modified="2009-10-13" version="1">MIDLRLLRTDPERVRASQRARGEDPALVDALLSADEARRAAVSRFDTLRNEQKVLGKQIPKAAGEEKAALLEQAKKLADGVKAAEADQHEADDVLKQLQLSLSNVVIDGVPEGGEDDFVLRETVGTPRDFAADGFEPRDHVELGKLLGAIDLERGVKVGGARQYYLTGVGALLEIALLNMAMAQATTYGFTPMITPSLVKPEAMAGTGFLGQAAENVYHLTEDDMYLVGTSEVPLAAYHMDEILDAAKLPLRYAGYSSCYRREAGSYGKDTRGIIRVHQFEKVEMFSYVLPEEAEAEHLRLLGWEKEFLTALEIPFRVIDVAAGDLGSSAARKYDCEAWIPTQGKYREVTSTSNCTEFQARRLQIRMRGADGVKPLATLNGTLCAMTRMIVAILENHQNADGSVTVPAALRPYLGGREKLEPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJV0</accession>
    <name>C7QJV0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalose 6-phosphate phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4324</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="EC" id="3.1.3.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792917.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4324"/>
    <dbReference type="EnsemblBacteria" id="ACU73188">
        <property type="protein sequence ID" value="ACU73188"/>
        <property type="gene ID" value="Caci_4324"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4324"/>
    <dbReference type="eggNOG" id="COG1877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037265_0_0_11"/>
    <dbReference type="OMA" id="HKLAKHP"/>
    <dbReference type="OrthoDB" id="1374424at2"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044651">
        <property type="entry name" value="OTSB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43768">
        <property type="entry name" value="PTHR43768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="27970" checksum="35D374187F953C32" modified="2009-10-13" version="1">MTNRQPPRARLTGAAGLFFDFDGTLAGIQEDPETVTPVSGVIPALTALAQRAKVVGIVSARPLSFLAEHFDEVPGLRLSGLYGLESSIAGERFTDPEAAGWEPAIREARERAQEELPGDVRIEDKRLALAIHYRSAPELRSGIEDWVSATAAATGLDVRIGRMVVELVPPVRRDKGSVVRSWCEGLDTAWYFGDDIGDRAAFEALAERQHDNPGFTAVRVAIVNSESEHGLAEQADVVLDAPSAVVGYIEDLLDVSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX5</accession>
    <name>C7QJX5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792942.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4349"/>
    <dbReference type="EnsemblBacteria" id="ACU73213">
        <property type="protein sequence ID" value="ACU73213"/>
        <property type="gene ID" value="Caci_4349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4349"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_3_11"/>
    <dbReference type="OMA" id="QTVTHYV"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16902" checksum="92AC00E013C64957" modified="2009-10-13" version="1">MDQLDAEIVRLLQADARQSNRELARTLGVAPSTCLERVRSLTRRGVIRGYHAEIDTAALNRGVQALVAVQIRPLSRSVIDAFSDFASALPEVLSTFVLSGGDDFVLHVGVPDLDRLHMFLTDRLAKRREVTGFRTSVIFKQVHQAVPERLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK40</accession>
    <name>C7QK40_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron permease FTR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EfeM/EfeO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794843.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6260"/>
    <dbReference type="EnsemblBacteria" id="ACU75114">
        <property type="protein sequence ID" value="ACU75114"/>
        <property type="gene ID" value="Caci_6260"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6260"/>
    <dbReference type="eggNOG" id="COG2822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050342_2_1_11"/>
    <dbReference type="OrthoDB" id="1430947at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14656">
        <property type="entry name" value="Imelysin-like_EfeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034981">
        <property type="entry name" value="Imelysin-like_EfeO/Algp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983207" evidence="4">
        <location>
            <begin position="29"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M75" evidence="5">
        <location>
            <begin position="146"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="41053" checksum="B746CA8CAB033973" modified="2009-10-13" version="1" precursor="true">MRRASWQVRLAVVPIVTAAAVVAGVAQSHPASAGGPIAVRASGCGTPPAAADAGRVDFVVTDDTDAFATVYLVDTADLVYAEIPWLTPGRTLPLTTTLGAGRYAIRCVLSDGTVHTTSQFSVSGTTSGAVAGYKPLPDLDMTAPVNAYRDWLGGSIPKLLAASKKLDADVASGDLRTAKADWLTAHLDYERLGAAYNSFGDFDGAIDGTAQGLPDGTADKDWAGLHAIEYGLWHGGSAEKIRPLTQALVGSVQGLVEDFPSEEVDPGDLPLRAHEILENTLQFQITGAADAGSGTSLATAYANTEGTQEVLSVLAPLIDDRAPGLRAKLAAEIAAVQGDLQATRDGSGGSGGSGGSGGSDGWTPAGAISAAQHRRLDADMDQLLEDLATIPNLLAPRTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ6</accession>
    <name>C7QKQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8332"/>
    <dbReference type="EnsemblBacteria" id="ACU77155">
        <property type="protein sequence ID" value="ACU77155"/>
        <property type="gene ID" value="Caci_8332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8332"/>
    <dbReference type="eggNOG" id="ENOG50343Y7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_833402_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35979" checksum="DA32D151B59626B6" modified="2009-10-13" version="1">MSGEQLERRYRGLLRILPKPYREAREEELLSVLMEGATEGRQWPELREALSLARLGMRVRLGAATDGARTSTRTGETVRAVGIVGSMLLAFLSLAQIAINTRSIQENPYAHWGLWRPFTVYYPGQSKYSLVPFEVPILWLLVLALITVGWWRAARVLALGVFLVSLYLSDGTLKVLQQETVLAAVVTGALFAARGVHARPTFLAGSLAVLASVGVGAWLYEGHGGPPMKAALAFEGWGYTDNRHAMVMAAVGAAAVGVLAHRSPVWPTALAVVTVAALVPVFVQNAVRPTYGGADQIPLAFLACALVCVAGLAVLKVWRARRLERSESPASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVN7</accession>
    <name>C7PVN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2361"/>
    <dbReference type="EnsemblBacteria" id="ACU71279">
        <property type="protein sequence ID" value="ACU71279"/>
        <property type="gene ID" value="Caci_2361"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2361"/>
    <dbReference type="HOGENOM" id="CLU_1515246_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18873" checksum="EDFC3E161FCE9993" modified="2009-10-13" version="1" precursor="true">MTLSPARKGLIAAVAAHLVALVGLLVTAQWDRAALWVVAGGFAVLAVGLPWMLMALCVDYVGDPAAWRRTVVVDGFATSEGYTVPPHPSDESYVLHRVYEFTTLRGETRRAGSRATFPEAPDGRIRLRYDPRRPTRIWPARIAPGTAAAGAVVTVLMLTAAAFALAGAIGFGLSSWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW17</accession>
    <name>C7PW17_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HesB/YadR/YfhF-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792994.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4401"/>
    <dbReference type="EnsemblBacteria" id="ACU73265">
        <property type="protein sequence ID" value="ACU73265"/>
        <property type="gene ID" value="Caci_4401"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4401"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173345_1_0_11"/>
    <dbReference type="OMA" id="AIGRQDQ"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10023" checksum="9BC4EE26B48716FC" modified="2009-10-13" version="1">MLSLTDRAAAAIQVLTTSSELPPETAGLRIVAADPSLNGNQDQFSAVLATGPDAGDQVVESGPARIFLESTAATVLDGRELDATVDVDGSVKFVVGPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW45</accession>
    <name>C7PW45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793022.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4429"/>
    <dbReference type="EnsemblBacteria" id="ACU73293">
        <property type="protein sequence ID" value="ACU73293"/>
        <property type="gene ID" value="Caci_4429"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4429"/>
    <dbReference type="eggNOG" id="COG3824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123836_1_0_11"/>
    <dbReference type="OMA" id="GEWYAGV"/>
    <dbReference type="OrthoDB" id="1867074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010428">
        <property type="entry name" value="Zincin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038555">
        <property type="entry name" value="Zincin_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06262">
        <property type="entry name" value="Zincin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="13078" checksum="6F658C342A6D54BD" modified="2009-10-13" version="1">MITIAPEQFEELVGQALDSIPPALGRQIRNVAVVVEAEAPYSGLLGLYEGVPLTGRGEWYSGVLPDRITIYRNEILKICHSYDDVVREVREVRTTVIHEVGHHFGIDDDRLHELGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWY6</accession>
    <name>C7PWY6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796968.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8420"/>
    <dbReference type="EnsemblBacteria" id="ACU77243">
        <property type="protein sequence ID" value="ACU77243"/>
        <property type="gene ID" value="Caci_8420"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8420"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_0_0_11"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19334" checksum="977B463366E25902" modified="2009-10-13" version="1">MSEAATGESAVRVHTAVLAIGGNLGDRLANLQSAIDSLADTPTLAIAWLSPVYETAPLLAEGADPQDDYLNAVLGVTSALPPDMLLMRTQAIEEALGRTRKIHWGARTIDIDIVQVDDLVSDDPELTLPHPRAAQRAFVLAPWHDARPDDVLTGAGPIADLLAALGGAAAQGAARRDDLELLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX01</accession>
    <name>C7PX01_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8435"/>
    <dbReference type="EnsemblBacteria" id="ACU77258">
        <property type="protein sequence ID" value="ACU77258"/>
        <property type="gene ID" value="Caci_8435"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8435"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="YWHTCLA"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="262"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="39088" checksum="6C9024DC6D6966DE" modified="2009-10-13" version="1">MITVELGLDELAATSFACSALLETGMSLRMWTHPGYYAEQVPLFNRMRPAFERLDTELLTALVGSWRWIPDFLTPRPTTPWPDFHRELATLRATPVERIWPELEQTFVKIDGAVPARLLRGRRDPAGLLAEIADEFEAYWETCLAPEWWPRARSVLESDIVYRARMLVERGAGTLFGELGDRLSWDGRRLRITWDASAYAAAVPKYDVPATGHGVLLAPTCFAHGALSMIEPTLSAWILYPARGLGTMAERVVPPPAGPALERLLGAPRARMLLMLGEPVSTTELARQLGVTPGAVSQHLKVLLDAGLTSRARHGRSVLYARSPLGDSLAGIAPPGLSHSGARRGQRDEDDDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXC5</accession>
    <name>C7PXC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0533"/>
    <dbReference type="EnsemblBacteria" id="ACU69476">
        <property type="protein sequence ID" value="ACU69476"/>
        <property type="gene ID" value="Caci_0533"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0533"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185062_0_0_11"/>
    <dbReference type="OMA" id="MERIAAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="94" mass="10730" checksum="DB7B8D68B3A4FE5B" modified="2009-10-13" version="1">MSELTDTTASPVPSVPQEPAKDLVVEYLLAKRPELGTIDPDYDLIDNRVLDSLGFVNFLYVLEEQTGREIALEEVSPEDFRTLRRIRARFFDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXR8</accession>
    <name>C7PXR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786814.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2603"/>
    <dbReference type="EnsemblBacteria" id="ACU71521">
        <property type="protein sequence ID" value="ACU71521"/>
        <property type="gene ID" value="Caci_2603"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2603"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_11"/>
    <dbReference type="OMA" id="GLCTEQF"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="6"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="43338" checksum="E5B51E3A8136514C" modified="2009-10-13" version="1">MSAGPVLITGLGALTPIGADVPTFAAALREGQCGIQVVADPDAPDQRRLLAPLPDPGLAGMLDGVEGLDPVQHKRFLRIARRSPFPVRAALTAAAQAWQDAELAKAPAPRDRIGIVVGGHNLTGHYAFELYPTYVRQPAHVPPRFALQAQDTDHVGTISEALGIEGEGCTVGASSASGNAALIHAARLVQTGAVDVCLAVGALARLGPLEVRSLANLGVSALVDAACRPFDRRRSGFVPGEAAACVVVESQDSVVRRGIPTDAAVELAGAAMVLAGTSLSDPSLASEVRAMAGALARAGIGAERIEYVNAHATGTPAGDDVEVDALIEVFGAGAGAGDGDGATAAQPWVNATKALIGHCLSSAGVVEAVAAVVQMRGGFIHPNPALAEPVTAGLRLVGTSAQPAAVVYALSNSFGFGGFNSSVVLRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY66</accession>
    <name>C7PY66_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795085.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6507"/>
    <dbReference type="EnsemblBacteria" id="ACU75356">
        <property type="protein sequence ID" value="ACU75356"/>
        <property type="gene ID" value="Caci_6507"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6507"/>
    <dbReference type="eggNOG" id="COG4922">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100997_2_1_11"/>
    <dbReference type="OMA" id="FIDATIN"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14187" checksum="404DD49F73BF5422" modified="2009-10-13" version="1">MTSTLSTEENRRLVLEAVSRFGAGDIAGFTELLGEGFVSHNPRVAHDPSAQSGREAFADFLSGPGSAHLRDATVAAKHLLADGDLVAVHTHVATPNGDLATVDIFRVDGGMLIEHWDVVQPIPDEVLHPHGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY79</accession>
    <name>C7PY79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795098.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6521"/>
    <dbReference type="EnsemblBacteria" id="ACU75369">
        <property type="protein sequence ID" value="ACU75369"/>
        <property type="gene ID" value="Caci_6521"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6521"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_4_5_11"/>
    <dbReference type="OMA" id="DSCANAC"/>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="22150" checksum="A2DA504BD8B1F952" modified="2009-10-13" version="1">MKFLVLGATGRTGVLFVTKALDEGHQVTALVRRAGSSVDPRAHIVTGDVADAAVIAKAAQGHDAIISALGVKSAGKTPTLITDMVQAVIESAKISGVDRFVLLSAFGVGDSLAKASWLVGPLFRTMLRKTYADKAASEVLLKASDLKWTLEYPGALNNGDSTHYSTVALEDVKRTPIFPSASRTNVADFLLRSAVGNTFIRQIAVVLDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY95</accession>
    <name>C7PY95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795114.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6537"/>
    <dbReference type="EnsemblBacteria" id="ACU75385">
        <property type="protein sequence ID" value="ACU75385"/>
        <property type="gene ID" value="Caci_6537"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6537"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="AAEHFFC"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="24569" checksum="A4C097C42406FFDE" modified="2009-10-13" version="1">MPGPGPTHSQPRGGRIAKRAAIIDGARAVFGRDGYTRASVDAIAAQAGVSTRTVYNHFGDKEHLFAEVVTGGATDVHSALSAHTAARLTPVTDAAQIEGALVALARDWVATMDLFPAHFAVARQVAAESAHLDPRLVEAWYESGPLAARTDLARHFDRLARSGLLRSDDPDRTARHFHLLAFAEITERSGNGAVPLPEAETELIIASGVRAFLTGYQKEQGRQIPQPPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC5</accession>
    <name>C7PYC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75415">
        <property type="protein sequence ID" value="ACU75415"/>
        <property type="gene ID" value="Caci_6569"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6569"/>
    <dbReference type="eggNOG" id="ENOG502ZPP7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_450482_0_0_11"/>
    <dbReference type="OMA" id="QSYAHFY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="584" mass="65181" checksum="C09904BA5611F534" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZB9</accession>
    <name>C7PZB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786869.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2660"/>
    <dbReference type="EnsemblBacteria" id="ACU71576">
        <property type="protein sequence ID" value="ACU71576"/>
        <property type="gene ID" value="Caci_2660"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2660"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="IHETDIA"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="28928" checksum="B0537CA8B37D7EEE" modified="2009-10-13" version="1">MIVVIGATGSVGKETVRLLRAAGHDVTAVTRNPSGADFPDGVRVAGGDPSRPGTLSAVWQGAEAVLISPRAAGAAAAELLADAAAHGVRRVSVISAATIDYPAGEPRFVLGFRAVESAARNSGLAWTFLRCADFAANALAWAPQLRVTGLVRAAFPDAATSPIHHRDIAEVAVSALTGPDHDGQAYVLTGPASLTQRDKVALISEATGRRLTLVEAAPDEIRAQMIAQGLPEEMPDRLLGSLADYAREPGPTTDTVAKLLGRPALDFATWAAENSAAFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZJ2</accession>
    <name>C7PZJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin dehydrogenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786942.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2735"/>
    <dbReference type="EnsemblBacteria" id="ACU71649">
        <property type="protein sequence ID" value="ACU71649"/>
        <property type="gene ID" value="Caci_2735"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2735"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_1_0_11"/>
    <dbReference type="OMA" id="GGTHIYR"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35139" checksum="4E68D086B20E84CA" modified="2009-10-13" version="1">MKPFDYRSPADAAEAVRSVAGDPTAVFLGGGTNLVDHLKLGVVEPGHVVGVADLLSAEIEELGEGGLRIGAGVSNSELAADPRVRERFPMLSQALLSGASAQLRNMATVGGNPLQRTRCVYFQDVTTPCNKREPGSGCSALGGWTRNHAILGASEHCIAVHPSDMAVAMAALKARVRVLGPDGDRTIAFVDLHRLPGDTPERDTVLEHGELITAIDLPAQPIARRSAYRKVRDRASYAFALVSVAAALDVADGVVVDARIAFGGVAHAPWRAYRAEEALRGSAAAESSYRAAADAELADARPAEGLDGGNAFKIPLLRRTLTAVLRDLAREDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZW9</accession>
    <name>C7PZW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4773"/>
    <dbReference type="EnsemblBacteria" id="ACU73634">
        <property type="protein sequence ID" value="ACU73634"/>
        <property type="gene ID" value="Caci_4773"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4773"/>
    <dbReference type="eggNOG" id="COG1266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080128_0_0_11"/>
    <dbReference type="OMA" id="LPDVWWK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="29284" checksum="013DDF5627B37457" modified="2009-10-13" version="1">MAVVDEGVAPAGGGPVPEARWRTLLRFEVLVVLALSFGQSAVYSLVSIIAKLTAKQALNQQSAGLNASESSRPWLDFTYQVLDLGFSLVIVALVAYLLMRENASLRTIGFDLAGGWRDWARGAVVAAGIGGAGLALYVSAHALNLNATVIPTTLPDVWWRVPILVLDAFRNGVTEEVVVLGYLLRRFEQLGFSRTKSEVMSSVVRGSYHLYQGFGGFVGNLVMGLIFCRAYRRWGRVMPLVIAHGLIDTVTFVGWLYWAHYLGIPGAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q092</accession>
    <name>C7Q092_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein-tyrosine phosphatase, low molecular weight</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797150.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8606"/>
    <dbReference type="EnsemblBacteria" id="ACU77425">
        <property type="protein sequence ID" value="ACU77425"/>
        <property type="gene ID" value="Caci_8606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8606"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_3_3_11"/>
    <dbReference type="OMA" id="DNAKERC"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14829" checksum="8B9A332755E71500" modified="2009-10-13" version="1">MSDTKPSVLFVCIHNAGRSQMAAGFLTHYAGDRVTVRSAGSAPADQVNPAVLEAMNEVGIDLSHETPKILTDEAALASDYIITMGCGDTCPVYPGKKYLDWVLTDPAGRGVEAVRPIRDEIEGLIKSLIDEIDAKNAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q096</accession>
    <name>C7Q096_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797154.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8610"/>
    <dbReference type="EnsemblBacteria" id="ACU77429">
        <property type="protein sequence ID" value="ACU77429"/>
        <property type="gene ID" value="Caci_8610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8610"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_0_11"/>
    <dbReference type="OrthoDB" id="1594866at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="42248" checksum="B4715C21EC7AAF6D" modified="2009-10-13" version="1">MLRQLSSIPTSGAAFLRGRRRALTDYRWRLVAALAISQTVGYGVLFYAFSVFLVPTAHGLHTSVPVVTGALTCSLLAAAAAAVPVGRYMDLHGGRLLMSTGSIAASVLVVGWSQVGAVWQLYAVWIGIGVASAAVLYEAAFAVIVSWFEPDSRAKALLAVTIFAGFASSIFLPSSGLLLADVGWRDAVLVLAGAHAALTVPFHLLVRRPSQLSMKGTCGGENDRRKVVAGAVRDPAFWMLGGSLLAQGAAVFVMGVLLVAALRDLGHSATFSAVAAGMLGVLSVSGRLAFTAAGKRASATDVAAVVFAIQAIGVGLLPLIGKSVVGAIACILTFGLGFGVSTLIRPAVLAARYGTDAFATLSGVLTTPLTLVKALAPLGAAAWAGSAHSYTPPLVTSAVCCLIGAAAMALTGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q191</accession>
    <name>C7Q191_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2857"/>
    <dbReference type="EnsemblBacteria" id="ACU71766">
        <property type="protein sequence ID" value="ACU71766"/>
        <property type="gene ID" value="Caci_2857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2857"/>
    <dbReference type="eggNOG" id="ENOG5033G8U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1774031_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="15960" checksum="4B2BF2E5BB02AC9D" modified="2009-10-13" version="1">MEQAATLVGAPVDNPLTELANLAGRARAWMELLQGRVEKLLEDFDDAEERRDREGGNAKNRGIRYQAGAGEQLRAEVSLYERSMDRLGKFLADYGRLGIDERLAKITESQAERVIAAIDAALAHAGVTGKVATEAKQVAARRLRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D4</accession>
    <name>C7Q1D4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793392.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4802"/>
    <dbReference type="EnsemblBacteria" id="ACU73663">
        <property type="protein sequence ID" value="ACU73663"/>
        <property type="gene ID" value="Caci_4802"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4802"/>
    <dbReference type="eggNOG" id="COG3076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076591_0_0_11"/>
    <dbReference type="OrthoDB" id="1479816at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016097">
        <property type="entry name" value="DUF695"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036701">
        <property type="entry name" value="RraB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009671">
        <property type="entry name" value="RraB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05117">
        <property type="entry name" value="DUF695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06877">
        <property type="entry name" value="RraB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89946">
        <property type="entry name" value="SSF89946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF695" evidence="1">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="RraB" evidence="2">
        <location>
            <begin position="146"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="27642" checksum="1E61A94C0AF7AC90" modified="2009-10-13" version="1">MSLGWDVYSCRVDGKPAVITLDLDLQDVADSGTHPQRLHVRHALRSPRENGLPDGTENDQMYALQDALVESLGAEVRAIYLACLTNDGHREHFFHLPPRADGRAVVAKVESALGDYELATFTEDDPEWRYYHEFLWPDTRSMQYLMDRRVVQSLAENGDKHSVPRPVDHVVGLPDEARARTMLVDAQAAGFTGRVEKRNGQWMVHLERTDAVELDYIHGVVWELHEMAERLGGYYDGWGCVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1J3</accession>
    <name>C7Q1J3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4862</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793451.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4862"/>
    <dbReference type="EnsemblBacteria" id="ACU73722">
        <property type="protein sequence ID" value="ACU73722"/>
        <property type="gene ID" value="Caci_4862"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4862"/>
    <dbReference type="eggNOG" id="COG3670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_1_2_11"/>
    <dbReference type="OMA" id="RAHGKVC"/>
    <dbReference type="OrthoDB" id="389495at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="PTHR10543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="470" mass="51993" checksum="0FEB923B04CB2EA6" modified="2009-10-13" version="1">MATDYDPGFTSLATEVEELALPVAGELPAWLSGTLFRNGPARFEGGEVPFRHWFDGQAMLHRFAIADGAVTYTNRFIDSASKRATDAGRIDYTEFATDPCQRYFSRMFTRFRSNTRDVQNANVNVAPLAEGMVALTEVPLAALFDPETLATAGIAAYRDDLQGQVTTAHPHQDPRTGDLVNYLLSFGRKSFYQVYRQAPTSMTRELVTRIPVARPGYMHSFAITENHVVLAEYPLTVNPLILLLSGKPFIDNYRWNARGTTRFLVVDTRDGSLRGEFHSEPFFAFHHINAFEDGDKLFLDICAYRDASVIDALYLDALAKEVPGDFPYPTRFEIDLTTGKVSSRRLADVTLELPRIHHGQHNGRPYRYAYGITGDSVGPVVARGLVKVDVESGQSKQWSQPRSYPGEPVFVPAPGALAEDEGVVLSVVLDGEAGTSRLVVLDAQSFQEVASATVPHAIPFGFHGLFHRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1N9</accession>
    <name>C7Q1N9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6745"/>
    <dbReference type="EnsemblBacteria" id="ACU75590">
        <property type="protein sequence ID" value="ACU75590"/>
        <property type="gene ID" value="Caci_6745"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6745"/>
    <dbReference type="HOGENOM" id="CLU_169716_0_0_11"/>
    <dbReference type="OMA" id="WEEEYEI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="9681" checksum="A941E3490765C1C0" modified="2009-10-13" version="1">MEEAPIRESYSFLCQACGHGWQEVYEIRRVHDSRGLIQSAFFLNGRRTPSPLTQGRCAVCASARVLVTQRTRGRRPRGGAMMEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S3</accession>
    <name>C7Q1S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795353.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6782"/>
    <dbReference type="EnsemblBacteria" id="ACU75624">
        <property type="protein sequence ID" value="ACU75624"/>
        <property type="gene ID" value="Caci_6782"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6782"/>
    <dbReference type="eggNOG" id="ENOG50318WM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077385_0_0_11"/>
    <dbReference type="OMA" id="LEMRASW"/>
    <dbReference type="OrthoDB" id="1265024at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021555">
        <property type="entry name" value="DUF3000"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11452">
        <property type="entry name" value="DUF3000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="20274" checksum="BB5E9A260B2B225C" modified="2009-10-13" version="1">MAPSRADDPREFAEAVAALTAASPPAAVELDPLPAPVNLAPFAHAVGGGVVVGDEDLATGRLVLLHRPGGHEEWRGAWRVVVLVEADLEAEIAEDPLLAEVAWSWLMDALAEHGAPFTAEGGTVSRSSSRGFGGLSGRPATTAVEIRASWTAVPGPDGGIDFGAHLQAWCALMMMCAGLPPEYEGVANLPPAGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q266</accession>
    <name>C7Q266_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797327.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8788"/>
    <dbReference type="EnsemblBacteria" id="ACU77603">
        <property type="protein sequence ID" value="ACU77603"/>
        <property type="gene ID" value="Caci_8788"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8788"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="GNIKSHA"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="107"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="20482" checksum="7A50AEFECD971401" modified="2009-10-13" version="1">MGDQARIEEFTEYAVARQNHLLRTAYLLCGDWHGAQDLTQTALLNLCKAWNRAKHADSIDAYAQKTLINVFIRSRRKLRRESELRAAALSGTERLGAGHDPDRPENRLALLAALDELSERARAVVVLRYWEDLSVEDTAAALGCSTGNIKSHASRALARLRVLLGEEFLAYDRDRATAPKGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P1</accession>
    <name>C7Q2P1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mucin-associated surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787076.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2874"/>
    <dbReference type="EnsemblBacteria" id="ACU71783">
        <property type="protein sequence ID" value="ACU71783"/>
        <property type="gene ID" value="Caci_2874"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2874"/>
    <dbReference type="eggNOG" id="ENOG502ZR7F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753754_0_0_11"/>
    <dbReference type="OrthoDB" id="1338921at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021235">
        <property type="entry name" value="DUF2637"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10935">
        <property type="entry name" value="DUF2637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="38979" checksum="DEF1DC4983ECE01C" modified="2009-10-13" version="1" precursor="true">MTENTETPDAKPRWRDALRDNGLASLAMILVVAVAVAGWAASFIALHAFAQQHMDLSERAAWLVPSTFDGAALALSLLSFRAAIYGRASLGSLLYVDGFTTLSSWINWIHINDPQGKLVSALLPIAAVLAFGKVLKEAREAYERRHGKVVFKVRTGLLMLRWTVDRKGTRAAIRNEILAIPVQALVGLGADTLARKAAEMLAEKVATDEAPAAVANRAGADNAAANTRSTTPTANPAATTTTVDSATAAKTATTTANDNQTPTDNRQNDNTAVANAKPVASAADANDNSATDKVEALVVATLGAYRQILADNTGKRANPRPTAPELVAAVEGLNTDSRAKQIREIVERRFPELAPRLRAVETVEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3C3</accession>
    <name>C7Q3C3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4999"/>
    <dbReference type="EnsemblBacteria" id="ACU73859">
        <property type="protein sequence ID" value="ACU73859"/>
        <property type="gene ID" value="Caci_4999"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4999"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_1_11"/>
    <dbReference type="OMA" id="RYLVYRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="33144" checksum="A45D96750DC69EA3" modified="2009-10-13" version="1">MDRALLADFLRARREALQPEDVGLPRGSRRRAGGLRREEVAMLAGMSTDYYSRIEQRRGPMPSEPILAALAQGLKLSPSEREHLFALGGHSAPRRSLRDERVSPAVTRIVERLGDTPAIVFSRFGEALLQTPGAVALFGDYTRFSGMSRYLVYRWFTDPAQRAIYPPEDHDLRGRVFTVDLRAAYTADPTGTAGEIVEALLAVSPAFAEVWRRHEVDVTHHHELKRYRHPVLGDLEMYSRRLYDPDEGQDLLVFMAEPGSASEEKLQRLIPADGSGDGAGDSSGSGDGDSRGSGSGAEALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3H7</accession>
    <name>C7Q3H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795470.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6905"/>
    <dbReference type="EnsemblBacteria" id="ACU75742">
        <property type="protein sequence ID" value="ACU75742"/>
        <property type="gene ID" value="Caci_6905"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6905"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="35804" checksum="E1D68D3FAA841A05" modified="2009-10-13" version="1">MATMNDVAALAGVSPSTVSYVMTGKRPIGEATRRKVLAAAKELNWEPNSRARALRSSHSNTLALVGPARTHAYAEVQGALVYALAQAAEDQGYDLLLKTTGAEPKDMVSLARSSVADAVILTDVLLEDPRVEKLRTLSFPMVLVGRPTESQHLNWVDLDFFGAGRATVDRLADLGHRVIAFFGPPPSAYKLQAGYAVRTLEGAREAALRRGVRLVAPPTTESLDGFADEVESAFRSAPEVTGVILQYEPATALIPQILAGLGRSIPDDVSIIAIAPSQLAMHARPPIDYVELQLTQMAQYAVRFAVDSIEGADPQSVLLPAEITNLGSVRQLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3P5</accession>
    <name>C7Q3P5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795538.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6980"/>
    <dbReference type="EnsemblBacteria" id="ACU75810">
        <property type="protein sequence ID" value="ACU75810"/>
        <property type="gene ID" value="Caci_6980"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6980"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="MTHDTIR"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22640" checksum="6E7919D2C5902EA0" modified="2009-10-13" version="1">MTHDTIRVVLADDHTVMRAGVVALLASEPTITIVGEAGDGREAVELVERLGADVALLDLRMPVLDGVAATTEIVAGKTGTRVLILTTYDTDAEIERAVEAGAIGYLLKDTTREQLVEAIRGAARGETVLAPRIAAKLVARMRQPAPVVLTTREVDVLNGVADGLSNADIGKRLVIAEATVKTHLLRVFAKLDVSDRTHAVVTALERGLLPRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Z2</accession>
    <name>C7Q3Z2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797474.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8937"/>
    <dbReference type="EnsemblBacteria" id="ACU77750">
        <property type="protein sequence ID" value="ACU77750"/>
        <property type="gene ID" value="Caci_8937"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8937"/>
    <dbReference type="eggNOG" id="ENOG5032WZU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_171862_0_0_11"/>
    <dbReference type="OMA" id="GVIVTAC"/>
    <dbReference type="OrthoDB" id="2014054at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="10301" checksum="4919102E9B9605CA" modified="2009-10-13" version="1">MSSIHFVVHALGALPADITNPAPADPTSGSNGVSLLLSYVKWGCLVAAAVAAVASGGLMAVGSLSNRPDHQEKGKRALVWSLGGVIVTACAIPLVNTVFGAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q483</accession>
    <name>C7Q483_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785237.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1015"/>
    <dbReference type="EnsemblBacteria" id="ACU69943">
        <property type="protein sequence ID" value="ACU69943"/>
        <property type="gene ID" value="Caci_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1015"/>
    <dbReference type="eggNOG" id="COG0386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029507_1_2_11"/>
    <dbReference type="OMA" id="FPMMSKI"/>
    <dbReference type="OrthoDB" id="1635499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="17759" checksum="16D5E63768A6DF14" modified="2009-10-13" version="1">MSLYDIPINTLDGKPASLKDYEGKTVLLVNVASRCGLTPQYEGLERLHERFADRGFTVVGVPCNQFGGQEPGTSEEIQEFCSATYGVTFPLTEKIDVNGDERHALYTELTKATDAEGGNGDIQWNFEKFLIGSDGTVLKRFRPRTEPEAAEVVEAIEAALPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B1</accession>
    <name>C7Q4B1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785265.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1045"/>
    <dbReference type="EnsemblBacteria" id="ACU69971">
        <property type="protein sequence ID" value="ACU69971"/>
        <property type="gene ID" value="Caci_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1045"/>
    <dbReference type="HOGENOM" id="CLU_838606_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="34754" checksum="5DB0E8D4FD8A0C3C" modified="2009-10-13" version="1">MNFDDSLREAMHGYAFTPSPVSAEQVMAGARRRRARDRARTAVGVVGVAALVSASVFVLLGTSSGSGGAVISPGFSPSASGTTAPDQVPPGQRSPVKQVKVGEAIKVPSDIDGAFYWMTTDSACRYAPHETTTYGKADLATSGFVECDTPAGGKNGRALICRMTVTAPPQTTGDTLPCAGHTPTDKYFSPLFAVQTIGGGNLMVPVAGVMAGPDLPTKVEDRVVDIYVGPDMSAGGHKVVRETRLETLYTVPGMKPGWKFWLPGSPLVYPNPNPPPDAPTYHGAPKQTKPVLTNSYDEIWLYDGANKRMTANPGNRPAPSATGFIPTDAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4F5</accession>
    <name>C7Q4F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787217.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3015"/>
    <dbReference type="EnsemblBacteria" id="ACU71924">
        <property type="protein sequence ID" value="ACU71924"/>
        <property type="gene ID" value="Caci_3015"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3015"/>
    <dbReference type="HOGENOM" id="CLU_2435457_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9579" checksum="595614EF6AEF60A8" modified="2009-10-13" version="1">MKDPAIPTPEQIRGLPVTSVAVFRKALGDIGLTVKPGSRNHLRVTTSTDAFIGTVPSSPSDPRSLRNCRAWLARRVAEVRDAAALASTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4G1</accession>
    <name>C7Q4G1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3021"/>
    <dbReference type="EnsemblBacteria" id="ACU71930">
        <property type="protein sequence ID" value="ACU71930"/>
        <property type="gene ID" value="Caci_3021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3021"/>
    <dbReference type="HOGENOM" id="CLU_2932784_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6717" checksum="3940B9F040203DBE" modified="2009-10-13" version="1">MNAILAKRVAHLEAERARPIPRLSKPDPNAPYTPQQQAQHRAEALADVYGTATRTHTETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4G7</accession>
    <name>C7Q4G7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3027"/>
    <dbReference type="EnsemblBacteria" id="ACU71936">
        <property type="protein sequence ID" value="ACU71936"/>
        <property type="gene ID" value="Caci_3027"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3027"/>
    <dbReference type="HOGENOM" id="CLU_1755550_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16197" checksum="E966EB8C4E3468D5" modified="2009-10-13" version="1">MIRLRKVHVLCGLLDFATGRLVITVDHMRCEKGSHSPMGRLVLPKGTCEHGPVAHYDSDDPRLEPVAAALAAVKRAEKQLAAKKDQLAGAVADAVRAGVRPSAIVKKTEYSAESIRQMLRAKEVDPLRPPTVTSIRKLQELQDARDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4L8</accession>
    <name>C7Q4L8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3078"/>
    <dbReference type="EnsemblBacteria" id="ACU71987">
        <property type="protein sequence ID" value="ACU71987"/>
        <property type="gene ID" value="Caci_3078"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3078"/>
    <dbReference type="eggNOG" id="ENOG5033KDT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841154_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="3">
        <location>
            <begin position="216"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="34547" checksum="53D7EE6BC439630B" modified="2009-10-13" version="1" precursor="true">MSGNPRRWLPAAVAVLAIAAMAAAARRDGPLDAGVSTGSLRDGRPVAALGAVILLAVVATAYAKHRDDGYGLLHRAGTATAVLLTAAAVLTPIGLLFFGRQPAPPPTQQLAPETTAPPRLPTGHGPDIKSTPNRPGDGPANWIVLVLLYLVLAAALGLLLYLVLRMLARRRFSRQELDLIDFDPLAPEFDQLAEAVAAGTEALEYEGDAREAVIACYSAMEVAVTAGGGGRRATDTPEEFLRRVTAANLIPGEPARRLTELFREARFSRHPIAEEKRDAAREALSAISLHLQGRAAELAASAQARAAAAQAAQSGQSAPPHASAPSGRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q542</accession>
    <name>C7Q542_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5131</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793719.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5131"/>
    <dbReference type="EnsemblBacteria" id="ACU73990">
        <property type="protein sequence ID" value="ACU73990"/>
        <property type="gene ID" value="Caci_5131"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5131"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="FIMPNAV"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="30"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="50193" checksum="1747E4E22EFB5683" modified="2009-10-13" version="1">MTTESTRTTETASLRPPSEPALPDPRRWWVLAAVAAAQLMIGLDLTIVNIALPSMQRSLGLSDPARQWVITIFALCYGGLLLLGGRMSDLIGRRRALMIGLTGFALASALGGAATDPAMLLGSRAAQGVFGALLTPAVLATLATTFTVPAERGRAFGIYGTAMGSASGVGVMLGGVLTQYLDWRWCMYVNVPIAIAAAAGVLYAVRPVPRNAGVRVDVLGALLATGGIMALVFGFARAQTDGWSAAITVVPLVIGVLTLVAFVFVQARTAKPLLPLRVVLNRRRAGSYLAVFSLAVGMFAALFFLTFFLQNVLGYSPIRAGLAFLPLTVGLIAGVRAVTKLLPRAPVRLLLCPGLLTIATGLALLGVVKADSGYWLHVFPVFFLVGIGTGWVLITANSAATLGAGQDTAVAGAMVMTSQQIGASLGTAVLSTIAGTAAAGYLHGHPGSGARAVVHGFDVASLGAAGFLCLAAVTVFLVSGRGEPKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5E1</accession>
    <name>C7Q5E1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="9" type="ordered locus">Caci_7080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7080"/>
    <dbReference type="EnsemblBacteria" id="ACU75910">
        <property type="protein sequence ID" value="ACU75910"/>
        <property type="gene ID" value="Caci_7080"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7080"/>
    <dbReference type="eggNOG" id="COG2262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019597_7_0_11"/>
    <dbReference type="OMA" id="AEMKTGR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="8">
        <location>
            <begin position="280"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="502" mass="55194" checksum="9C8C09DABCA550C2" modified="2009-10-13" version="1">MTESHKDAARDEVYALNDHDTPEAEWDTEDAFDAPAPLYRNRWADSRHDGEQFDLEERASLRRVAGLSTELEDVTEVEYRQLRLERVVLVGVWTDGTAADAEVSLRELAALAETAGSEVLDGVIQRREKPDPATYIGSGKALELRDIVVATGADTVICDGELSPGQLIHLEDVVKVKVIDRTALILDIFAQHAKSREGKAQVALAQMQYMLPRLRGWGQSLSRQMGGGRGGLATRGPGETKIETDRRRIRERMAKLRREINDMSKGRVTKRAERRRGSVPSVVLAGYTNAGKSSILNRLTGAGVLVENALFATLDPTVRRTETASGRAYTLSDTVGFVRHLPHQLVEAFRSTLEEVGESDLVLHVVDASDEDPEGQISAVRAVFADMGAGDVKELMVLNKADLADPEVLARLLRHEPHSIIVSARTGEGIDHLLSAIERDLPRPGVELEALVPYDRGDLVARIHAEGEMLKEEHTDHGTLVRALIHQNLAAQLEPFRTVGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5N3</accession>
    <name>C7Q5N3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_9031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9031"/>
    <dbReference type="EnsemblBacteria" id="ACU77844">
        <property type="protein sequence ID" value="ACU77844"/>
        <property type="gene ID" value="Caci_9031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9031"/>
    <dbReference type="HOGENOM" id="CLU_537147_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="53102" checksum="CDDC799CA32E90E8" modified="2009-10-13" version="1">MSPDMSVEDHGDGAVRGLLDSAFAGAEPPMRDLASGSIARGDAARRRNRRWAACGAVLSVLAVIGTFTAVTGATPARHRNPTPVTPATSSEPVYAPPSGPLGFGPGPASIDKMQDLKNRLPAALQPLLPAGIAFGQVGMHDDTVFINRMSGVLSGPSGSNLAAMWVGRAPAEDTAIRKFACQEGGTCETRIADGGTIYLDEHVYTAADQLRHIGVAVDALKPGTEKTVVSRSLSMLFVPADRTQYAFEFQIETAIAPIRYADRAPADVEPGIPWPPPVPEIPVSDPSGLLMSNDDLVAMLSRPGLHGLEYLLDYRTAIAPAAKAQVAAAGDRIAAAAGAALPPGVKAGIDSSETLPRLYLTGPTGTDQLNWTAFVLDAADRQREYGTCEAGDSCTRRTVPGGTLMINETYPNSDSATSSDTPLVDSYVFLPDDLSKPVLTMTLSSEPLSYRPGQPGQPVTATGAMPTLSRAPYAPLQVSRDQFLTAVENGQALTAITTTESLLAALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5S2</accession>
    <name>C7Q5S2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin carboxylase</fullName>
            <ecNumber evidence="1">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.4.14" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785313.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1093"/>
    <dbReference type="EnsemblBacteria" id="ACU70019">
        <property type="protein sequence ID" value="ACU70019"/>
        <property type="gene ID" value="Caci_1093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1093"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_2_11"/>
    <dbReference type="OMA" id="KITTWRT"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="459" mass="49692" checksum="04F931EC5E9C371D" modified="2009-10-13" version="1">MFKTVLIANRGEIALRVARTCRELGIRTVAVHSTADRESAVVRFADESVHIGPPSAKASYLHMPSIMEAALRTGADAIHPGYGFLSEDPDFAEVCQTHGVTFIGPPPHVIEKLGDKALARRLMAEAGLPVLPGSTGAVNGLAEARKVAERIGYPLILKAVAGGGGRGIAVVRAADQLTQAYRETCAHARAVFGDERLYIERFVEDARHIEVQVLCDRHGGAVHLGERDCSVQRRYQKLIEEAPAPNLPDELRQQMCAAAVRGALAVGYVGAATFEFVVSSDGSFHLMEVNCRLQVEHPVTEMSTGIDLVREQLLIAAGRPLSVRQEDLAPRGWSIESRVNAEDPERNFAPTPGLLTEFMPPGGPFVRVDSHAYPGWLMGPDYDSLLAKTVVWAPDREQAIARMDRALGEFRVEGQGLRTTIGFLREILAHPAHRAGTHTTGFVAEMRTETAAVRGGPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Z6</accession>
    <name>C7Q5Z6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785387.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1167"/>
    <dbReference type="EnsemblBacteria" id="ACU70093">
        <property type="protein sequence ID" value="ACU70093"/>
        <property type="gene ID" value="Caci_1167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1167"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_312774_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982551" evidence="2">
        <location>
            <begin position="34"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="799"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="852"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="894"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="947" mass="97031" checksum="DA7891062B8F4195" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q669</accession>
    <name>C7Q669_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="5">3.2.1.52</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3167</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.52" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3167"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72075">
        <property type="protein sequence ID" value="ACU72075"/>
        <property type="gene ID" value="Caci_3167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3167"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008392_0_1_11"/>
    <dbReference type="OMA" id="PIGVIFF"/>
    <dbReference type="OrthoDB" id="949956at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981433" evidence="3">
        <location>
            <begin position="43"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3" evidence="4">
        <location>
            <begin position="123"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="43856" checksum="859A31B89ECD1393" modified="2009-10-13" version="1" precursor="true">MADAGMRSGRGKKTGGVAAVTLVAAVGLLSGACSSGASKPAAQGSSSSSSTTTSSTPTTTSSSSTPTTTSSSSSSSSSAPSSSSSSTTPKPPTTPSSSPAAPGNLTLQQEAGQRVIYSYQGLTPPQHLLTLIRQGDVGGVIFFGGNISSQSQIAGVITELRQAQAASPVHLPLLLMTDQEGGIVKRLPGPPYDSAKQVGQSSNPPGAATAQGTAAGQNMAGVGMNLNLAPVLDVYRTPGNFLDAAQRSFSQNPNTVSQLGSNFIVAQQNTGVAATAKHFPGLGSAPNGANTDEHPVTLTVSLSNLRSIDELPYAAAVQNGLKLVMMSWAIYPALDANRPAGMSSTIVQQELRDRVGFKGVTITDALEAGALQAYGTAGNRALSAAEAGMDLLLCSSGDPAQGDAAAAALVAAVNNGKLSRSGFDAAVGRVDALRGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q677</accession>
    <name>C7Q677_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3175"/>
    <dbReference type="EnsemblBacteria" id="ACU72083">
        <property type="protein sequence ID" value="ACU72083"/>
        <property type="gene ID" value="Caci_3175"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3175"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_7_1_11"/>
    <dbReference type="OMA" id="MHSHPYN"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019921">
        <property type="entry name" value="Lucif-like_OxRdtase_Rv2161c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03619">
        <property type="entry name" value="F420_Rv2161c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="28864" checksum="16055E7E026D3C15" modified="2009-10-13" version="1">MHIGFAPHRLWPTDPADLAGVLDTARLIESLGFEHVIAGTHLLAGDLGLSPDPMVLLSAVAGATSRVRVATSILIAPLYEPLVVAHQAATLDALSGGRLVLGVGTGWDRAEFDAVGVPFTERGKRTDAGLATMRALWRGESEVSLGMPPRTPDGPPVWIGGTSDAALRRALRFGDAWHGSGDPDAVTAARARIAQLAEGTDRDPDSLGLTVVSMLLPPGFELSGKSPGALLGGDQPSRESIVDELGRLEEAGVSSCSLWAPVDAAALPDVLGWAAELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6C5</accession>
    <name>C7Q6C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787424.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3224"/>
    <dbReference type="EnsemblBacteria" id="ACU72131">
        <property type="protein sequence ID" value="ACU72131"/>
        <property type="gene ID" value="Caci_3224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3224"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="MWWSTYE"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="10"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="42882" checksum="E6CA9F7FFB2C828E" modified="2009-10-13" version="1" precursor="true">MSTAQKTRTALVIGGGIAGPVTATALHKAGIQAIVYEAHAELGEGIGGGLALAPNGMAALDTIGVGDAVRAAATPIAGTRMAIDGKIHELPSLAGVEPLQIVGRGDLHRLLRERALEAGVGFEYGKRLIEATETADGVEARFADGTTASADVLIGADGVRSTVRTLIDPAAPGADYTGLLSFQGYVDAAPDLDVEPGMMTFAFGKRAYYLYWKQADGRLTWGANLPSKTYMSLTEARAIPADKWLRRLRDTYRDDTPGHLLADRTTPDTLDITGAIHIMPPVPHWHTARVALVGDAVHAPSNSTGQGASLAIESALHLARTLRDIPNPATAFATYETLRRPRVERITKRGARTNRKKTPGPLGRKVMHATMPLFFKLMNFDKVLGWEQRYRIDWEAPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6U5</accession>
    <name>C7Q6U5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795686.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7128"/>
    <dbReference type="ESTHER" id="catad-c7q6u5">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75958">
        <property type="protein sequence ID" value="ACU75958"/>
        <property type="gene ID" value="Caci_7128"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7128"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_3_1_11"/>
    <dbReference type="OMA" id="IHGAWSR"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="28000" checksum="3FDDFA33E5BCF5BC" modified="2009-10-13" version="1">MQTTPVVLIHGAWLHASSWEAWAERFARHGYAVDVPGWPGEEPTVAAARRNLDPVRDLRIGDLLAHYERIARSCDTPAVLIGHALGGLIAQRLLGAGIGQAAVAIAPQPPTGLVLPDAESNRMSSKLFSASVEDNGFVPMPRQQFRSLVANTVGEQEAGKLYERYALPAPHRLLTEGELAVNTDNTARGPLLLVSGQEDRMVTDAVTRATYKLYSDSTAVTDLKQFADRGHSLVFDSGWRDIADYVLTWLADNVSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q753</accession>
    <name>C7Q753_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpA</name>
        <name evidence="14" type="ordered locus">Caci_1216</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785435.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1216"/>
    <dbReference type="EnsemblBacteria" id="ACU70141">
        <property type="protein sequence ID" value="ACU70141"/>
        <property type="gene ID" value="Caci_1216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1216"/>
    <dbReference type="eggNOG" id="COG0056">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010091_2_1_11"/>
    <dbReference type="OMA" id="LQAPGVM"/>
    <dbReference type="OrthoDB" id="837522at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="13">
        <location>
            <begin position="31"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="11">
        <location>
            <begin position="153"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="12">
        <location>
            <begin position="383"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="173"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="10">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU70141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="58546" checksum="AD40BAAB43E88DEE" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C1</accession>
    <name>C7Q7C1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785503.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1284"/>
    <dbReference type="EnsemblBacteria" id="ACU70209">
        <property type="protein sequence ID" value="ACU70209"/>
        <property type="gene ID" value="Caci_1284"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1284"/>
    <dbReference type="eggNOG" id="ENOG50337NN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1915328_0_0_11"/>
    <dbReference type="OMA" id="HAEVCRI"/>
    <dbReference type="OrthoDB" id="1938802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15592" checksum="06D22A0B01D6E0A1" modified="2009-10-13" version="1">MSTDNLPEPTSGDDDVSAELIAASLRADTADLEVYARVLSTNLIETLPPGAVRLERKRSLADRAAGREGRVESVDVTLGEQRMTLRLAKHGPVGEVCKEVRGIVLSRQQVALDVWIQTLSAAIADTARSNAKAREVLQRFVLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K6</accession>
    <name>C7Q7K6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787492.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3292"/>
    <dbReference type="EnsemblBacteria" id="ACU72199">
        <property type="protein sequence ID" value="ACU72199"/>
        <property type="gene ID" value="Caci_3292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3292"/>
    <dbReference type="eggNOG" id="COG2764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_17_2_11"/>
    <dbReference type="OMA" id="GFRVMAY"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16078" checksum="C0EDA551D40DB71A" modified="2009-10-13" version="1">MNTTDTATLKSTTHINFRGDARPALEFYRDVFDGDLTVITYGAMNAAQRPEEADQIMWGQVTAPSGFAIMAYDVPADRPYAKGVAPFFESVRGESLEAVTPVWKKLSEGATVLQELAPSPWAPAYGMLTDRFGVTWVVDVAADTVPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7N8</accession>
    <name>C7Q7N8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosidase PH1107-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787524.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3324"/>
    <dbReference type="EnsemblBacteria" id="ACU72231">
        <property type="protein sequence ID" value="ACU72231"/>
        <property type="gene ID" value="Caci_3324"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3324"/>
    <dbReference type="eggNOG" id="COG2152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_640768_0_0_11"/>
    <dbReference type="OMA" id="NCGSPIE"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="505" mass="55767" checksum="1C09329CDC8296A5" modified="2009-10-13" version="1">MTTAESVPAQSPARGLEADELVTRRRLRLNRDPSRVIAKLFLPGGQPPDMNSRAGGVVRRVLTLSDVEVEASYTQILEQFGSRHRDLQETFAENYRTIEHRVGHDKDVSEQRRLLIGAHFTHEYAIEGAALTNPSMVPHPDQSGLRPGELRFLMSARAIGEGHLSCVEFRTGVIGSGGELRVDQPSPHASIGSVRATRYERSLLAAAMAGHGEDDEVVAYLLRHLPEHFTDAELEARLGELHPQLLVQENTYRTVSRIHWFLACQYRLEFSADADVSEHVLWPQSPTERRGVEDARFVRCVDPDGSVMYRGTYTAYSGSDSATQLMETPDFQTFQMSQLFGPAVGSKGLALFPRQVEGRHVALSRWDPESNAIATSQDGRIWQRAGSLDAPLRQWELTQVGNCGSPIETEAGWLALTHGVGPMRTYALGAILLDLKDPTQVVGTLRDPLLIAAPDERDGYVPNVVYSCGALKHEDLLVIPYGFGDMGIEFATVSVSGLLERLEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7S2</accession>
    <name>C7Q7S2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3358"/>
    <dbReference type="EnsemblBacteria" id="ACU72265">
        <property type="protein sequence ID" value="ACU72265"/>
        <property type="gene ID" value="Caci_3358"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3358"/>
    <dbReference type="eggNOG" id="ENOG5032ZBB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166645_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045423">
        <property type="entry name" value="DUF6510"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20120">
        <property type="entry name" value="DUF6510"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="12580" checksum="2773584988C1E5E1" modified="2009-10-13" version="1">MSESFREPSADPFGELFGEPFSESLPVFSDEDDYEDGNALAGPLSEIFAVDVVSAQGCCTGCGTTGPIAQLRVYGPGPGLVARCPQCGQVVLRLVRGGNSAWLDLRGTVSLRIPLDTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7S4</accession>
    <name>C7Q7S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3360"/>
    <dbReference type="EnsemblBacteria" id="ACU72267">
        <property type="protein sequence ID" value="ACU72267"/>
        <property type="gene ID" value="Caci_3360"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3360"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094953_0_0_11"/>
    <dbReference type="OMA" id="WESAGYH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="47"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="23984" checksum="89B83E1AB46C50CA" modified="2009-10-13" version="1">MRAAAPPGRIWAMAIVSRGFQGRRRSSEHRLPPGQYETRDFPVLSAGPTPRVDRDAWRFSVVTEGGERRSWTWPQLMALPAERPVVDLHCVTKWSKFGTAWQGVSLDMLLADVETEAEFALVHAYGGYTTNVPLKDLLDGQAWIAYGYDGRDLTPEHGGPARLLVPHLYLWKSAKWVRGIELMVRDSPGFWESAGYHDYGDPWREQRYQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q818</accession>
    <name>C7Q818_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_5326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793914.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5326"/>
    <dbReference type="EnsemblBacteria" id="ACU74185">
        <property type="protein sequence ID" value="ACU74185"/>
        <property type="gene ID" value="Caci_5326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5326"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="FQGLRFM"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="125"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="40450" checksum="E2BF98FA7E2FA620" modified="2009-10-13" version="1">MVAVERTLPSDESRALFGLVQDLCAKELAPRAAEYEAAERFPREVFRTLGQAGLLGLPYDEEYGGGGQPYEVYLQVVEELARTWLTIGLGVSVHSLACYGLANYGSAEQKAKWLPGMLGGDQLGAYCLSEPQSGSDAAALTTRAVRSGDEYAVTGTKAWITHSGQADFYTLMVRTSDDGAKGISALLAENGTPGLGFGKPEKKMGMRGSVTAQVLLDGARVPADRLLGAEGQGFSIALSALEAGRLGIAACAVGVAQAALDAAVEYATSRRQFGHAIAEFQGVGFMLADMATAVAVGRAAYLAAARRRDAGLPYGTEAAMAKLFCTDMAMKVTTDAVQVFGGYGYTADFPVERYMREAKVLQIVEGTNQVQRLVISRNLTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L8</accession>
    <name>C7Q8L8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1360"/>
    <dbReference type="EnsemblBacteria" id="ACU70283">
        <property type="protein sequence ID" value="ACU70283"/>
        <property type="gene ID" value="Caci_1360"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1360"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_5_1_11"/>
    <dbReference type="OMA" id="DYRTIDN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="4">
        <location>
            <begin position="267"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="409" mass="42611" checksum="61753DCF63BA8518" modified="2009-10-13" version="1">MRFDPEQQELRQTVRTLLDRAAGGDVWRLLTEQVGALELAIPEQYGGAGFSVLETHVVLEELGAALAAPGYLSTTVAAQAILAGDSEQAKAELLPGIAGGGTRAAVVWSGTVEAVVEAAVGGGGDGWRLTGIEEHVLDGGDSGLFVAQARMPGARGEAAGKPDSGRAPRQESGAGRGQARAETGLGQAQESATDRGQAREAAIGRGPWQSLDAHSVSGYGVFVVSAADAVVSAVETVDPGRPQACVEFRDSPAIFLGADPLLLERVLDLACVAISAEQVGAAQRAFDLTLAYAKQRVQFGRPIGSFQAVKHRLADMFTLLESARSASYAAAFAAVSGNELTVAASRAKAYCSEAFSTIAGEAIQLHGGIGITWEHPIHLYFKRAHVTSQLFGTPAWHRRRYALASGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q994</accession>
    <name>C7Q994_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793969.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5381"/>
    <dbReference type="EnsemblBacteria" id="ACU74240">
        <property type="protein sequence ID" value="ACU74240"/>
        <property type="gene ID" value="Caci_5381"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5381"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914288_0_0_11"/>
    <dbReference type="OMA" id="DAGCFAQ"/>
    <dbReference type="OrthoDB" id="1481884at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982927" evidence="2">
        <location>
            <begin position="28"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="30741" checksum="FAABB7C469EB4750" modified="2009-10-13" version="1" precursor="true">MTASRIGRGALVTLAGAAASLAGAAGAANACEQKPPPPKPCTLDTHDVTWAQVGKDGKDIAKPAPAAHFTQVKTEPQYGFRVELTQSALQQQCTGSVDISLASYNAEGPTWETSGTQSFVDFATVHLTTTSKTSASQVLTVKLPGVPGGPCFGQIDLYPGSTKYDGTNGHGIPNYHNGVNTPKGVFAAWNGADAGGCTVVTPPPPPVTTTTPPPATTTPPTTAPTTHPSTPVSSTTPPPPPRTSTTTSTPTTPPTTTATPGTPTLAETGSNAGELSLVALAFFGAGGTAMFASRKAKAAEARKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9A5</accession>
    <name>C7Q9A5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1524 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5392"/>
    <dbReference type="EnsemblBacteria" id="ACU74251">
        <property type="protein sequence ID" value="ACU74251"/>
        <property type="gene ID" value="Caci_5392"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5392"/>
    <dbReference type="eggNOG" id="COG2356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043034_0_1_11"/>
    <dbReference type="OMA" id="LAYAWDM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="DUF1524"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="DUF1524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982646" description="DUF1524 domain-containing protein" evidence="2">
        <location>
            <begin position="43"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1524" evidence="3">
        <location>
            <begin position="138"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="28566" checksum="DF74AE5CD560A20A" modified="2009-10-13" version="1" precursor="true">MVHRIRSKAFAGAGSRRMLPVVALAVSAALLAGCKPVDDAGASSGASSGGSGGAGGKNTSGPVSSDGHAVSPLTDPDGTKAGLAPITSAADLGAARDLIGRVGTRNPASLSGYTRDKFGQAWTDGATGDPFAGNGCDTRDDVLERDGQNIQDQAKGKAAHCVVEAMTLANPYTGQSIQFTKKNATAIQIDHVIPLAYSWQMGSSGWTAARREQLANDPLELLAVDGSDNEAKGDSGPAAWMPPLKAIGCSYSVRFAQVAIKYQFPVTSADKSAMLAQCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9G8</accession>
    <name>C7Q9G8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794043.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5455"/>
    <dbReference type="EnsemblBacteria" id="ACU74314">
        <property type="protein sequence ID" value="ACU74314"/>
        <property type="gene ID" value="Caci_5455"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5455"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061385_1_0_11"/>
    <dbReference type="OMA" id="PRGARHM"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07726">
        <property type="entry name" value="ST1585-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037482">
        <property type="entry name" value="ST1585_MBL-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="21"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34782" checksum="6D78769C8EA3ED00" modified="2009-10-13" version="1">MTNLGSDVHEIDTLMSGHTGITAGYAILGEHPALIETGTAKSAPVVRDALAALGVGPEDLRTIVVTHIHLDHAGGVGDLAAMFPNAEIVVHASGARHLVDPTRLMSSARRVFGSLMDDVFGPLLPTEARRVRAVEDVGSIDLGGGRRLETHHTPGHARHHVGLIDNVTGDLYVGDAAGLYIPSDDPDQPGDVRPGTPPPDFDLPLALNSLEKFRTLRPTRLLFSHYGPVRDVTDTLARAEEEVRLWVELVRDARTSRLDLDHAIEMVREKTAARYPVETANEETQTKFEELSSFASNIVGINMYLNKADGWEHPMADAASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9W1</accession>
    <name>C7Q9W1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fatty acid hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_7455</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7455"/>
    <dbReference type="EnsemblBacteria" id="ACU76280">
        <property type="protein sequence ID" value="ACU76280"/>
        <property type="gene ID" value="Caci_7455"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7455"/>
    <dbReference type="eggNOG" id="COG3000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034756_3_1_11"/>
    <dbReference type="OMA" id="WTHYLIH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid alpha-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="PTHR12863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="10">
        <location>
            <begin position="85"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27797" checksum="98AA3A8C55A38003" modified="2009-10-13" version="1">MTAVADNADNNRNASNRTVSNRTVSNRTAVTRTAFTRSGMTLREAASLFARHPNSRALAATTATAAATRLVLGKWSRRDAVAAAAILATEPFVEWMIHVHVLHRRPREKKDGAVADSLLASSHRAHHSDPRDPDLVFIPRPAVAPSIAVLALANLAGARALRPALTGFATAIASMTTYEWTHFLIHSAYRPQSSLYKTIRRTHQFHHFRNENYWFGIITPVSDKVLNTYPDKDDVAVSSTAKALDARDRIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBQ6</accession>
    <name>C7QBQ6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PAP2_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1712</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785927.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1712"/>
    <dbReference type="EnsemblBacteria" id="ACU70633">
        <property type="protein sequence ID" value="ACU70633"/>
        <property type="gene ID" value="Caci_1712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1712"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056733_2_0_11"/>
    <dbReference type="OrthoDB" id="1742143at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="PAP2_3" evidence="7">
        <location>
            <begin position="85"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="36047" checksum="B9370976E5788356" modified="2009-10-13" version="1">MTTTQPLENSTETTARDGDVEAAPQAGARRRSWIPGPVLPQKFRPTNRPKLWLEIALIALGYYLYTLTRLAAPAHESAAQDRGHDILRVEHFLGLNFERSFNHWVYSVRWLAFSMNVYYATLHFIVPIAVLVWVYFKFPDRYRAIRTVMISMTLIALFGFYFYSLAPPRLLENGNFVDTFKLLNPWGQTSATSDGVAGLGKSTNEFAAMPSLHIGWSTWCALVIAHLAQRRWVKVLGIAYPFCTFAVIIGTANHYVLDAVGGLVTLGLGFLVQRIIQGRPVFAPVPKPAGEAPLPRQPDGSATAPEPDDGVSAELVRPPIHTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBR8</accession>
    <name>C7QBR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792266.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3634"/>
    <dbReference type="EnsemblBacteria" id="ACU72537">
        <property type="protein sequence ID" value="ACU72537"/>
        <property type="gene ID" value="Caci_3634"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3634"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040286_1_0_11"/>
    <dbReference type="OMA" id="EQAKWFG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="4">
        <location>
            <begin position="264"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="286"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="455"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="525" mass="56427" checksum="A58136F0122FD200" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBX4</accession>
    <name>C7QBX4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792322.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3691"/>
    <dbReference type="EnsemblBacteria" id="ACU72593">
        <property type="protein sequence ID" value="ACU72593"/>
        <property type="gene ID" value="Caci_3691"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3691"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040294_0_0_11"/>
    <dbReference type="OMA" id="IMPNHEV"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020051">
        <property type="entry name" value="SagB-type_dehydrogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03605">
        <property type="entry name" value="antibiot_sagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="353"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="551" mass="59532" checksum="E3ACE3C56147B7B8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC99</accession>
    <name>C7QC99_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="8" type="ordered locus">Caci_5689</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794276.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5689"/>
    <dbReference type="EnsemblBacteria" id="ACU74547">
        <property type="protein sequence ID" value="ACU74547"/>
        <property type="gene ID" value="Caci_5689"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5689"/>
    <dbReference type="eggNOG" id="COG1921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038142_0_0_11"/>
    <dbReference type="OMA" id="GATNRTH"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="7">
        <location>
            <begin position="11"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="455" mass="46186" checksum="B9C22FD87256BB8F" modified="2009-10-13" version="1">MAGALGESDPRRSVPRTDTLLADPRLKHAAATLGPQAVKLAVRSAQQQVRTGLAAPADAADLALALLATAPVTLRPVVNATGVVLHTNLGRAPLSAAAVEAMSRAAGYVDVEFDLEAGGRAGRGRTVKAALLAAVPAAEDVHIVNNGAAALVLAACALAGGREIVVSRGELVEIGDGFRIPDLLTAAGAVLREVGTTNRTHLRDYAEAIGPATGFILKIHPSNFRIEGFTSSVPVAELSGLGVPVVADIGSGLLGPHPLLPTEPDAGTWLSQGADVVTASCDKLLGGPQAGLILGSGERVAEMRRHPMARALRVGKTTLAALQATVGGHETPVEAALTADREVLRVRADAMSTALTSSGVQAETVASAGAVGGGSAPGVTLPGWAVRVPEQFAEPLRIGEPSIVGRVEHGFCLLDLRCVPAALDEQVCAAVLAAGRRAAGRPGRRPPELTAASCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM0</accession>
    <name>C7QCM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796208.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7659"/>
    <dbReference type="EnsemblBacteria" id="ACU76483">
        <property type="protein sequence ID" value="ACU76483"/>
        <property type="gene ID" value="Caci_7659"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7659"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="TIAMKPE"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="52"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="32636" checksum="75C9F48392C002E2" modified="2009-10-13" version="1">MTEIDEHGGVATASSADAPTQQLPAVAPDQDPAAGAGSGVAAAGRSGRLVGLQTQDLSAWFGDHKVLERVSLSMAPGEVTALIGPSGCGKSTYLRILNRMHEMVKSAQLAGRVLLDGDDIYAPGRRPADVRARVGMVFQRPNPFPAMSIYDNVVSGLKLAGIKAGRARREELVETSLTQAGLWAEVRNRLRSPGGALSGGQQQRLCIARSLAVEPDVLLMDEPCSALDPTSTRRVEETIADLRGRLTIVIVTHNMQQAARVSQNCAFFLATHDTPGRIVEAGPTRQLFEDPRDERTSDYVNGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS5</accession>
    <name>C7QCS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="8">3.5.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7714</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7714"/>
    <dbReference type="EnsemblBacteria" id="ACU76538">
        <property type="protein sequence ID" value="ACU76538"/>
        <property type="gene ID" value="Caci_7714"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7714"/>
    <dbReference type="eggNOG" id="COG1820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032482_2_1_11"/>
    <dbReference type="OMA" id="MFNHAPT"/>
    <dbReference type="OrthoDB" id="1026967at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047419">
        <property type="term" value="F:N-acetylgalactosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="65"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="325"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="43343" checksum="8FF297A845832A4F" modified="2009-10-13" version="1">MNIGLDIADWSSPQSFLVTSISAPRVLLGGRLAGPATVVVDGGVVAEVLDGASPEADIALDSGVLAPGLVDIQTNGCFGVDFITASEQDWRRVSDRLPSTGVTAFQPTYITAPLETLLAGVDRAAAVFGSLRGAQAMGVHLEGPFLSPLRPGVHDPRYLVAPTPEGVGAIVATLTAERTRGVVTMVTLAPELEGGPEAVRRLSEAGVRVSLGHTDALAEQVIAAADQGATLVTHIFNAQRPLNHREPGVPGAALYDTRFTCGLIADLHHVAPEICTLVWRAAGGRVALVTDAIAAAGMPPGEYELSGIKVHLGEDGVPRDAAGVIGGSALTLDRAVRNMVGIGLDEASVLVAATRVPADALGRSDLGRIEAGARADLVWFDDGYHPLRTWVAGRSVFEAGSGAQAPDGSHRLAREHQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS6</accession>
    <name>C7QCS6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796264.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7715"/>
    <dbReference type="EnsemblBacteria" id="ACU76539">
        <property type="protein sequence ID" value="ACU76539"/>
        <property type="gene ID" value="Caci_7715"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7715"/>
    <dbReference type="HOGENOM" id="CLU_1052486_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="27048" checksum="BFF98141C6C8C14C" modified="2009-10-13" version="1">MSEFEEALARSVQDGIARGGLPGAADAVRQGRRRSLRARGGVTMLGVAVVAGALGGAGVLGGGTGTAAGSGTDSFKHADDGVLPAAQWPAYDVAHWKVAPSCSVADRSKCRPGDPTDDIKQVKAGDLTGQCGPTKSFPVLRFVQYATQEDELLKLDGDEIVLTLPSRAAAAAFMAEARTAGSPRACAGVPGAEGVTPGVDTADGVSWEWTEAPPNAAMYGHGYLVRVDDRVAFLRLNQTGGGDTVRGTAGDETVLKNLEAALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCW0</accession>
    <name>C7QCW0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_1749</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1749"/>
    <dbReference type="EnsemblBacteria" id="ACU70670">
        <property type="protein sequence ID" value="ACU70670"/>
        <property type="gene ID" value="Caci_1749"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1749"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026437_0_0_11"/>
    <dbReference type="OMA" id="ARDHRKY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLOBIN" evidence="15">
        <location>
            <begin position="51"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="165"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU70670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="482" mass="52732" checksum="022A4F86070AC98B" modified="2009-10-13" version="1">MVRQAAMGSTDLDPARVPALIRESFALVGGESGSSGNSDNSDKPDKIVSYFYALVFTECPALRDMFPPMMDAQRDRLFQALVRIVGQAEHPDSLVAYLRELGRDHRKYGAQPEHYDVVWRCLISALKHYAGAAWTPDMDAAWLAAYQLIAGTMMEAAEQDAQLAPAWWTARVVRHELRTPDIAVLTLQPDSPYEFRAGQYLSLETQRWPRVWRHFSIANAPRSDNTLTLHVRAIPAGWVSTALVNHTRVGDVVRLGPPSGTMLCTTTSMRDLLCIAGGTGLAPIKAMVEDMAKWNTTRQVRLFYGARHDDELYDLAALEHLAYRRRWLSVVSAVSHDPHFPGERGMLPDVVARHGEFFEHWAGHDVYVSGSVAMVRATIARLQELNIPLASIRFDAYGGMDGLWQPGAGQGVPMPPSAPAGPGTAGEGRTEGVGHANGAGVSTAGSWAAQGAWRRDNGWRAGVAGQVGAARTLDEWLVSQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDB1</accession>
    <name>C7QDB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792433.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="SMR" id="C7QDB1"/>
    <dbReference type="STRING" id="479433.Caci_3803"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH95">
        <property type="family name" value="Glycoside Hydrolase Family 95"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72704">
        <property type="protein sequence ID" value="ACU72704"/>
        <property type="gene ID" value="Caci_3803"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3803"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004617_0_0_11"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027414">
        <property type="entry name" value="GH95_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14498">
        <property type="entry name" value="Glyco_hyd_65N_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B-type lectin" evidence="1">
        <location>
            <begin position="803"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="943" mass="98763" checksum="2580AA6850C2B733" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDB8</accession>
    <name>C7QDB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3810"/>
    <dbReference type="EnsemblBacteria" id="ACU72711">
        <property type="protein sequence ID" value="ACU72711"/>
        <property type="gene ID" value="Caci_3810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3810"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_11"/>
    <dbReference type="OMA" id="HAIFINT"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="26"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="130"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36310" checksum="6B7981DD66CF5359" modified="2009-10-13" version="1">MHRPEALLVMRPDTYRLQFGAEELRRLRALAELGDPVWTDDLDTPRVRARLAETEVLLTSWGCPVLTEERLDAAPKLRAVFHCAGSVRPIVSDAVWRRDVLVTSAAEANATPVAEYTLAAIIFAGKQAHVLAAQSRLKPVDWYAVGDREDLSNYGRTIGIVGFSRIGRRVLERLRALDTAAVLVADPYADSEAVAAAGGQLVELDEVLKRSEILSLHLPELPQTRGSIGARELALLPDGATVVNTARGSVIDTAALERECASGRLNAILDVTDPEPLPADSLLPSLPNVMITPHIAGSLGTETRRMSAQALSELERFVRGEAPLDAVTREVLAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDH7</accession>
    <name>C7QDH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792499.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3882"/>
    <dbReference type="EnsemblBacteria" id="ACU72770">
        <property type="protein sequence ID" value="ACU72770"/>
        <property type="gene ID" value="Caci_3882"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3882"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051820_2_0_11"/>
    <dbReference type="OMA" id="WIRCHAY"/>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="74"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="372" mass="40969" checksum="8082A2FA026DC211" modified="2009-10-13" version="1">MKNWWIYKGSGPASKRLALLAENQPRWRTFDGVVDDGYVVPDLAEPRYARERERGAGYLVDAPDVDVVNTALLLRRPLLVTGEPGVGKSTLAFSIAADLGLGPVLRWAITSRSTLREGQYRYDAVRRLEDANLRELKRKAAEAMVTGVRQDKLGSRDGDRRESPDRPERQGTPRPDAIGNYLQLGPLGTAFLPTRRPRVLLIDEIDKGDIDLPGDLLTVLEDGEFEIPELSRMAAHEADVEVGTSDFDGHSVVSRGWIRCHAYPIVVLTSNGEREFPAPFLRRCIRLNIGRPDDEKLRSIVEQRIGPEAAAEAAAPGGLISTFIERRRSGEVATDQLLNAVQMRLAGAWTAPEDLASLADATLHRLTGPDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDS2</accession>
    <name>C7QDS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl xylan esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794425.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5838"/>
    <dbReference type="ESTHER" id="catad-c7qds2">
        <property type="family name" value="Acetyl-esterase_deacetylase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74696">
        <property type="protein sequence ID" value="ACU74696"/>
        <property type="gene ID" value="Caci_5838"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5838"/>
    <dbReference type="eggNOG" id="COG3458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_871183_0_0_11"/>
    <dbReference type="OMA" id="YIIGGCV"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="35034" checksum="178F92551A8FE4A4" modified="2009-10-13" version="1">MKIDRLSQSAGVPQHPFPFDPAYGLDLDGLLKVAAPDTVPADFAEFWQDMYRRALATPVDPRLGAKAGSTAAGLDVFEVSFTSLGGIRIGGWIVVPPDGVVERGFVVGHGYGGRDEPAPELPATDAAGIYFVARGLPTKSLLSGVPSEAPGHVLQGIESRADYIIGGCVADLWCAATALTELFPATARRLDYTGVSFGGGTGALALPWDARFTAAQLMVPTFGNHRLRVTLECVGSGASVRERYQHDPRILDVLAYFDAATAARHVQIPVQAVPALFDPAVPPPGQFAVVNALAGPVETQVATAGHFTDYPEYEQEMLELGRATKQFFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDY7</accession>
    <name>C7QDY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7751"/>
    <dbReference type="EnsemblBacteria" id="ACU76575">
        <property type="protein sequence ID" value="ACU76575"/>
        <property type="gene ID" value="Caci_7751"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7751"/>
    <dbReference type="eggNOG" id="ENOG5033KN2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104209_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982776" evidence="2">
        <location>
            <begin position="32"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="19282" checksum="1D02DE887C9F128A" modified="2009-10-13" version="1" precursor="true">MTWVPVKPTRRTLLAVTGVALLGGCASPAGKASSGSSPAKPVPAGQPDPVRDRVLAAEADLLARYDATLALPSVTADSALTAKLTAIRAEHAAHVTAIKQGYTPPSTPTPSSGSATPAPSPSTPSSPPTLSSPGATTWSPSATTDAKTAVSVLAGAEQDAAGARTTDILAADGATAMLLASIAASESGHAALLLGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE01</accession>
    <name>C7QE01_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4328 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796314.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7765"/>
    <dbReference type="EnsemblBacteria" id="ACU76589">
        <property type="protein sequence ID" value="ACU76589"/>
        <property type="gene ID" value="Caci_7765"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7765"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753755_0_0_11"/>
    <dbReference type="OMA" id="QTITRAQ"/>
    <dbReference type="OrthoDB" id="2027656at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025565">
        <property type="entry name" value="DUF4328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14219">
        <property type="entry name" value="DUF4328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4328" evidence="3">
        <location>
            <begin position="69"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="38642" checksum="74C4E112034C4E91" modified="2009-10-13" version="1">MPGVTGSPISPYGYPAPYGANVPRIRTSVQSLGTAVTVLLALDAALAVLAAGLLAWRNTLIGDFLGDPASVDPDRMNTADQAAGSATGWFIILTVATAVVFICWFWAARNNAEVYAPNRGSLPTGWAIGGWFIPLAGLVMPGIVARDIHRGTMAGRDNTRATGGMITGWWWSSYVAFWIMCVVVSVQNGRARNAADPLEHLHDVRSASEAGIIALSVGVAAALLAITYVQTITRAQRARIREAGWYAPGQPWAYGMPYGYGAPMPGYPMGMPVPMPMPGPGQPPMPAGPPAFGMPVAMPMPGQPPMPTGSDAFGMPVAMPMQDVPVQNPIPAAHPQTAETQTAETQTADVQPTEPPKEPGDWPNPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE17</accession>
    <name>C7QE17_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetolactate synthase</fullName>
            <ecNumber evidence="6">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_7781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7781"/>
    <dbReference type="EnsemblBacteria" id="ACU76605">
        <property type="protein sequence ID" value="ACU76605"/>
        <property type="gene ID" value="Caci_7781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7781"/>
    <dbReference type="eggNOG" id="COG0440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055003_1_3_11"/>
    <dbReference type="OMA" id="EPYGIKE"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="11">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU76605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="22791" checksum="BAEFC38B74B8D0CB" modified="2009-10-13" version="1">MSRHTLSVLVENKPGVLTRVAGLFARRAFNIESLAVGPTEHEDVSRITLVVTVEDHPLEQVTKQLNKLVNVLKIVELDPAASVQRELLLVKVRCDQDSRAEVLATVQLFRAKIVDVAPDAVTVEATGDSEKIEALLRVLEPFGVKELVQSGMVAIGRGSRSIADRPLRTVTPEDVRAHHEGNHAHAANGSRDNHNRTHRKQMSDHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE59</accession>
    <name>C7QE59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796372.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7823"/>
    <dbReference type="EnsemblBacteria" id="ACU76647">
        <property type="protein sequence ID" value="ACU76647"/>
        <property type="gene ID" value="Caci_7823"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7823"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="26098" checksum="C0A0FB30A32CA3F3" modified="2009-10-13" version="1" precursor="true">MPAEKKIAMVTGGASGIGRATAELFAARGAAAVVVVDRTDTGEYSGPETVELIRKAGGTALFVRADVSVEAEVEAAVGAAVAEYGRLDAAVNCAGVAGTGAKIGDTALEDWNRVLGVNLTGVFLSLKHEIRAMLPNRSGTIVNIASAAGLVAVPYLSPYCSSKHGVLGLTKTAAREYRNAGLRINAICPGVVDTPMIHTSAQERPAVNMQARENTGGFVGQPEQIATAAVWLCSPEASFVNGESMVVDGGTITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE96</accession>
    <name>C7QE96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1867"/>
    <dbReference type="EnsemblBacteria" id="ACU70787">
        <property type="protein sequence ID" value="ACU70787"/>
        <property type="gene ID" value="Caci_1867"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1867"/>
    <dbReference type="eggNOG" id="COG0074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036192_0_0_11"/>
    <dbReference type="OMA" id="TGDRWFT"/>
    <dbReference type="OrthoDB" id="1636709at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009499">
        <property type="entry name" value="DUF1116"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024033">
        <property type="entry name" value="Uncharacterised_dom_sf_YlbE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06545">
        <property type="entry name" value="DUF1116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="52211" checksum="65DD7457B3460F73" modified="2009-10-13" version="1">MSLLEGSGAGVSMARLEPTHVVAAGLAGFADDLVEQGVAVTRVDWRPPPPGTEGDLADVAVDARRGEANALAVRRMLAAGCELVDVRPASEVLGVEPGQFLHAGPPIGWERASGPLRGALIGAALFEGLVETADDAVDWFSGGSGSGASSTSRTAPELAPCHHRGGVGPMAGVVSPSMWLLEVRDPVGGGTSWCSLNEGLGKVLRYGAFGPEVVERLRWMAGVLGPMLQRGVRRRGAVDVKAIVAQMLHMGDEGHNRNRAGTLMLLREVLPSLIEGGEDGRELADVVRFVSGNDHFFLNLVMPACKLAGLAASGVAGSTVVTVMARNGTDFGIQTSGTGDRWFTGPANTPEGLFLAGYGPEDANPDIGDSAITETAGVGGFAMAAAPAIARLVGGTAASAVATTRLMYEITLAENPAFTVPALDFRGTPTGIDVGRVVRTGVLPQINTGMAGRVAGTGQVGAGLVTPPMECFTQALAALAELARADETRADLAPENHPTQRPTNPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEF2</accession>
    <name>C7QEF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786136.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1923"/>
    <dbReference type="EnsemblBacteria" id="ACU70843">
        <property type="protein sequence ID" value="ACU70843"/>
        <property type="gene ID" value="Caci_1923"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1923"/>
    <dbReference type="eggNOG" id="COG4877">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156623_0_2_11"/>
    <dbReference type="OrthoDB" id="2101132at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="10225" checksum="7ACBBC956D312D27" modified="2009-10-13" version="1">MSPRKQILLRLDASVHDALARWAGDELRSTTAQIEYVLRQALAQAGRLPDDVGKMPRRGRPPKGAAAGEAAHGDQAGDEDGQADRADQASPGPDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG2</accession>
    <name>C7QEG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine-specific ribonuclease N1 and T1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1933</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786146.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1933"/>
    <dbReference type="EnsemblBacteria" id="ACU70853">
        <property type="protein sequence ID" value="ACU70853"/>
        <property type="gene ID" value="Caci_1933"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1933"/>
    <dbReference type="eggNOG" id="COG4290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1862898_0_0_11"/>
    <dbReference type="OMA" id="WPDSANA"/>
    <dbReference type="OrthoDB" id="1964970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980894" evidence="4">
        <location>
            <begin position="33"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="15068" checksum="3F95E7DCE9570512" modified="2009-10-13" version="1" precursor="true">MSSLRRFGLSWTQRLAVGFAATASAVTVTVVASPAADATVYGSCTVSGCSAAASANSTWESMNYPSSRGWYDWPNGKCNYAGGTYYNDDGQLPSGDSFQEFDVNPRACGAHRDAVRIVVDMNTGQVWYSPDHYSDFYALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN9</accession>
    <name>C7QEN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792538.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3923"/>
    <dbReference type="EnsemblBacteria" id="ACU72809">
        <property type="protein sequence ID" value="ACU72809"/>
        <property type="gene ID" value="Caci_3923"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3923"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_2_11"/>
    <dbReference type="OMA" id="DAGFYKH"/>
    <dbReference type="OrthoDB" id="916788at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="86"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="30787" checksum="DD2CB40E6FE1E45F" modified="2009-10-13" version="1" precursor="true">MVAATSSAVNAEESRTAASKPSKRVDDRWRETALVWSLRLAVIALCFALWQVMSGPVLPEYAVSKPTQVWRALRALLSSSSGWTDIETTAFEVVVGFAIGVAAGIVMGLVLGSFRLAGRVMEPLVAAVNGVPKIALAPLFVLFFGIGSWSKIYIAATGVAFVVFYNVYLGLRLRERELVEIIQVMGGRRHHVLSYVTIPTLAAPFFAALKTGGPLAILGVIGGEFIAASQGVGHELFNSAMNLDAAGEFASLAVLMGMTLILNSVLTTLDKYALRRLGLATRRQSGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEU8</accession>
    <name>C7QEU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3992"/>
    <dbReference type="EnsemblBacteria" id="ACU72868">
        <property type="protein sequence ID" value="ACU72868"/>
        <property type="gene ID" value="Caci_3992"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3992"/>
    <dbReference type="HOGENOM" id="CLU_203330_0_1_11"/>
    <dbReference type="OMA" id="IIGFATH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="55" mass="5719" checksum="30B80E67DFB10CDB" modified="2009-10-13" version="1" precursor="true">MVVLLLLVILAIVLGIVGTVAKGLLYLLIIGVVVFVLALVLGAVKLRRGGKKPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFE4</accession>
    <name>C7QFE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7898</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796446.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7898"/>
    <dbReference type="EnsemblBacteria" id="ACU76721">
        <property type="protein sequence ID" value="ACU76721"/>
        <property type="gene ID" value="Caci_7898"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7898"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_1_0_11"/>
    <dbReference type="OMA" id="KYAMLGF"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="725"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="811"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="17"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="294"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="754"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="853" mass="87228" checksum="C3AF76A4B454371E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFH3</accession>
    <name>C7QFH3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7927"/>
    <dbReference type="EnsemblBacteria" id="ACU76750">
        <property type="protein sequence ID" value="ACU76750"/>
        <property type="gene ID" value="Caci_7927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7927"/>
    <dbReference type="eggNOG" id="COG1615">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007733_1_0_11"/>
    <dbReference type="OMA" id="HLRYPQD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005372">
        <property type="entry name" value="UPF0182"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39344">
        <property type="entry name" value="PTHR39344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03699">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="461"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="715"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="962" mass="103169" checksum="A5347005C8419700" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFI4</accession>
    <name>C7QFI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7938"/>
    <dbReference type="EnsemblBacteria" id="ACU76761">
        <property type="protein sequence ID" value="ACU76761"/>
        <property type="gene ID" value="Caci_7938"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7938"/>
    <dbReference type="eggNOG" id="ENOG5033S9V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037038_0_0_11"/>
    <dbReference type="OMA" id="FPWYGLD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28494" checksum="4FFCC7D10DFB3BB1" modified="2009-10-13" version="1">MSSTISTEDFPDPPGPASQPGSLAPVADGAAAASGAVAEADKRPGRTSALDDFVPGPPIASISAAALAASEPDAWPGQRTAVPWYGLDEAWVGDRWLGSIMLGPDGVAEYGTLGHGDHPARRPDDLSPRRFCGVVTMARLDRRPGGGAAVLEPTTLSTLAAVAGLGLLSDAWPWAVDKALRGDWLHQQTDLAYEVAENLDDAPWRAVQLPVDGKPTRFRYRESEYGWVLAAELRECWLGAYGRGVTAYGLGFEQVTLDAWEAYEALPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFJ5</accession>
    <name>C7QFJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyl-diaminopimelate desuccinylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796497.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7949"/>
    <dbReference type="EnsemblBacteria" id="ACU76772">
        <property type="protein sequence ID" value="ACU76772"/>
        <property type="gene ID" value="Caci_7949"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7949"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_1_0_11"/>
    <dbReference type="OMA" id="LNSHHDT"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010174">
        <property type="entry name" value="Succinyl-DAP_deSuclase_DapE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01900">
        <property type="entry name" value="dapE-gram_pos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="177"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="39897" checksum="DD80FC4690A5ECF2" modified="2009-10-13" version="1">MSGLDLTQSAARLTAALVDIESESGNEKALADAVEEALRKYPHLEVLRDGDSVLARTNLGRAERVILAGHLDTVPIAVDSTGRRNVPSLLQGDWETGTLRGCGTSDMKAGVAVQLVLAATLAEPNRDVTYVFYECEEVEAERNSLGRLIRTRPEWFAADFAVLLEPSNNIVEGGCQGTMRARLTFRGARAHSARSWLGDNAIHKAGAAMRRLAEYQPRRVEVEGLEFREGLNAVGISGGVAGNVIPDECSVLVNFRFAPDRGQDDAERHVREVFADLDAEIVVTDSAPAARPGLHLPLAAEFVGAVMEGMDAEPTAKFGWTDVARFAELGVPGVNYGPGEGSLAHKPDESVDLGQVVRCAERMRSWLGSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG32</accession>
    <name>C7QG32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786302.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2090"/>
    <dbReference type="EnsemblBacteria" id="ACU71009">
        <property type="protein sequence ID" value="ACU71009"/>
        <property type="gene ID" value="Caci_2090"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2090"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="AYLFCGD"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="15"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="171" mass="19244" checksum="7E95AC5FBC173FA5" modified="2009-10-13" version="1">MSEAEDEFREFAVAVQGHLRRSAYLLCGDWHLAEDIVQSAFVKIFRVWRRVRKVENQLGYARQVVYRCFLDQYRKDKKQLPTVPIAGAADHVLVESVLDDSSFAGVVVEALAELPPRARAVIVLRFWEDMSVEQAATVLGVTTGTVKSQTSRAVAQLRGRLAAGLNEQARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGH5</accession>
    <name>C7QGH5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine oxidase ThiO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5997"/>
    <dbReference type="EnsemblBacteria" id="ACU74855">
        <property type="protein sequence ID" value="ACU74855"/>
        <property type="gene ID" value="Caci_5997"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5997"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_5_11"/>
    <dbReference type="OMA" id="CRRLEPM"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012727">
        <property type="entry name" value="Gly_oxidase_ThiO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02352">
        <property type="entry name" value="thiamin_ThiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="11"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="388" mass="41394" checksum="88BFDE4BCCB92951" modified="2009-10-13" version="1">MWTMRSPAGSDVLIIGGGLIGLAAAWRTAVRGLSVTICDPAPGSNASFAAAGMLTPVTELHYGEETLLSLNLASAKRYPSFIEELREASDGLDPGYREAGTLVVAFDADDREVLSELHVFQQSLGLKAEWLTGREARRLEPMLAPGVRGGLLVSGDHQVDNRMLLAALFAALERDPKVTIVRSKVAELTVTGDRATGVVLEDGTALPAAQVVLSAGCWSGQIAGIPEELLPPVRPIKGQILRLAIPDVFKPFLSRTVRYVVRNNHAYLVPRAHGELVLGATVEEQDYDTAVTAGGVYELLRDARELVPGITELPLIETRAALRPGTPDNAPLIGPTALPGLLYATGHYRHGVLLTPATADGVAEILATGTVPEALAPFSPRRFEHHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK5</accession>
    <name>C7QGK5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase U62 modulator of DNA gyrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6028</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6028"/>
    <dbReference type="EnsemblBacteria" id="ACU74885">
        <property type="protein sequence ID" value="ACU74885"/>
        <property type="gene ID" value="Caci_6028"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6028"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046126_1_0_11"/>
    <dbReference type="OMA" id="TRNGVWL"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="225"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="467" mass="48506" checksum="5613C2D666CB67E5" modified="2009-10-13" version="1">MSPDTAVRSETAERVLQAARTAAGGSADVDVTVEHEHLALTRFANSYIHQNVASDTDTVTLRIHADGRTAVNTTTVTDDAGLAALVERTVAAVRLSPADPGWAGLSGRAPLPIPSADPDLATGGAGPEARAEQVKAYVDEVTAAGLTAAGFYRNRLVVTAYANSEGQAVHGTVVEAAIDGIAKTATSDGASRQASRRMSDLNGAALGARAAAKALASQNPIEIDPGEYEVVLEPTAVSDILWVLADYGFNGKALTEGTSFAKLGDQQFDPLVTLIDDPLSGPAAGPLFDAEGTPRDPLHLVRNGVTQAVAHDRRSAREAATTSTGHASASSATDGAVPINVRLEPPVTLTPTEVDGPAADSAVQGLITKVHRGLLVTDHWYTRCLDPRRLVMTGLTRNGVWLIENGEITHPVKNLRFTQSYPEALAPGRVLAIGTHAPAFASKYGAYSAMAPALHLAGWNFTGGASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS9</accession>
    <name>C7QGS9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsZ</name>
        <name evidence="11" type="ordered locus">Caci_6104</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="6">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794688.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6104"/>
    <dbReference type="EnsemblBacteria" id="ACU74959">
        <property type="protein sequence ID" value="ACU74959"/>
        <property type="gene ID" value="Caci_6104"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6104"/>
    <dbReference type="eggNOG" id="COG0206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024865_2_0_11"/>
    <dbReference type="OMA" id="GNPSIGQ"/>
    <dbReference type="OrthoDB" id="1009041at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="9">
        <location>
            <begin position="10"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="10">
        <location>
            <begin position="204"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="18"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="105"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="40582" checksum="3820F673DE75FD90" modified="2009-10-13" version="1">MAAPQNYLAVIKVAGIGGGGVNAINRMIEVGLKGVEFIAVNTDAQALLMSDADVKLDVGRELTRGLGAGANPDVGRKAAEDHAEEIEEVLKGADMVFVTAGEGGGTGTGGAPVVARIARELGALTIGVVTRPFTFEGRRRANQAEDGIAALREEVDTLIVIPNDRLLSISDKNVSVLDAFKAADQVLLSGVQGITDLITTPGLINLDFADVKSVMSEAGSALMGIGSARGDDRAVAAAEMAISSPLLEASIDGARGVLLSISGGSDLGLFEINEAAQLVSEAAHPEANIIFGAVIDDGLGDEVRVTVIAAGFDGGEPAKRRTGHSQAAGATRYDEETSVRDGMREQVLGTLPKPAERGAGVPAHDPMADTQNVPVIPVQPAPSAADELDIPDFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU9</accession>
    <name>C7QGU9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="8">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_7976</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8 11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 11">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796524.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7976"/>
    <dbReference type="EnsemblBacteria" id="ACU76799">
        <property type="protein sequence ID" value="ACU76799"/>
        <property type="gene ID" value="Caci_7976"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7976"/>
    <dbReference type="eggNOG" id="COG0538">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023296_1_1_11"/>
    <dbReference type="OMA" id="HGTVQRH"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="PTHR11822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 12" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="13">
        <location>
            <begin position="13"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="98"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="313"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="9">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU76799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="45513" checksum="F60F5265AE8CBDB9" modified="2009-10-13" version="1">MAYSGPKIKVANPVVELDGDEMTRIIWQFIKDSLILPYLDVDLKYFDLGIEHRDATDDQVTVDAANAIKQYGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILDGVIFREPIVISNIPRLVPGWTKPIVVGRHAFGDQYRATDLKVPGEGTLTLTFTPKDGGEPVELNVFDFPGSGVALAMYNLDESIRGFARASMRYGLNRGYPVYLSTKNTILKGYDGRFKDIFQEVFDTEFKAEFDAAGLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMAPDGKTVEAEAAHGTVTRHYRQHQQGKPTSTNPIASIYAWTQGLAYRGKFDNTPEVVKFAETLERVCVQTVEEGKMTKDLALLVSPDQPYLTTQEFLAAIDENLQKAMTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI05</accession>
    <name>C7QI05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792779.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4186"/>
    <dbReference type="EnsemblBacteria" id="ACU73050">
        <property type="protein sequence ID" value="ACU73050"/>
        <property type="gene ID" value="Caci_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4186"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_5_11"/>
    <dbReference type="OMA" id="YVFCLNV"/>
    <dbReference type="OrthoDB" id="1278342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="421" mass="42737" checksum="A362337E602E9FD6" modified="2009-10-13" version="1">MTISAPARAPQKTSLNPEPAASPRPRVSARALLRASGGPRYAVALLVDSFGSGMLRPFLLLYGINVLRLSAPVSGAAMTVGIIAGLCVAPLAGRWLDHGARSTVVAASMLIRVLGTIVLLTAPAGNVAVFTTAALFLGIGNQTMPTAHSALIATIATGRERDAAVAAARSLRNAGMGLGALAATACLAGGPAAMRWLAAATGASYMVSALLAWSVRIRAQPTSAKESGVHAATAPGMRVLLPANVIYAFCLIIPEIALPLIVVKMLHASPAWAAGIFVTNTALVVALQVPVTVWLARWPRSVALAAAGGMVSVSYIGFLLASSLGHGLAAPAVGAVSVLCTVGEIMYAGTVGPLLMAITPAPVLGRALSRFQLSNGLGLAIAPMVITFLAAHGAAVLWLPLAAATLVAAWSVRRLSEGELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI77</accession>
    <name>C7QI77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792851.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4258"/>
    <dbReference type="EnsemblBacteria" id="ACU73122">
        <property type="protein sequence ID" value="ACU73122"/>
        <property type="gene ID" value="Caci_4258"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4258"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_7_0_11"/>
    <dbReference type="OMA" id="LAYSYRQ"/>
    <dbReference type="OrthoDB" id="1452079at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="306"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="486"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="547" mass="57872" checksum="D032F6707D0F70DF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG1</accession>
    <name>C7QIG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6184</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.157" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6184"/>
    <dbReference type="EnsemblBacteria" id="ACU75038">
        <property type="protein sequence ID" value="ACU75038"/>
        <property type="gene ID" value="Caci_6184"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6184"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_2_11"/>
    <dbReference type="OMA" id="HPVRLYD"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041040">
        <property type="entry name" value="3HCDH_RFF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18321">
        <property type="entry name" value="3HCDH_RFF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="3">
        <location>
            <begin position="10"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="2">
        <location>
            <begin position="190"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH_RFF" evidence="4">
        <location>
            <begin position="314"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="2">
        <location>
            <begin position="377"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="55307" checksum="5C71F828E71271D6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ9</accession>
    <name>C7QIJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794805.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6222"/>
    <dbReference type="EnsemblBacteria" id="ACU75076">
        <property type="protein sequence ID" value="ACU75076"/>
        <property type="gene ID" value="Caci_6222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6222"/>
    <dbReference type="eggNOG" id="ENOG5033ZRM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2235033_0_0_11"/>
    <dbReference type="OMA" id="QARHPYK"/>
    <dbReference type="OrthoDB" id="1818849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11962" checksum="6ED2AC127FAA3402" modified="2009-10-13" version="1">MINHTMMVSFVEPLPDAELDRYLADIERVLLETGVVQSFASARHITVPGEEEIPALIATVIVQIGVADRDALAKAFAAPGIEEVIGHWQARHPYKVGWANHEPLLATQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIT4</accession>
    <name>C7QIT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8161"/>
    <dbReference type="EnsemblBacteria" id="ACU76984">
        <property type="protein sequence ID" value="ACU76984"/>
        <property type="gene ID" value="Caci_8161"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8161"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059193_0_0_11"/>
    <dbReference type="OMA" id="MAWTNIV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14606">
        <property type="entry name" value="Lipase_GDSL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="173"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="38171" checksum="D47299AB3C6761C6" modified="2009-10-13" version="1">MTAHNGVGDSARTEMSNADRSQRAGASRHASVEPYLAGCAWPSGQGAAYPRADPKDFARLPIDTWGTATVPVGVRLEFAGAARAIQIAYRTKTADLGYRGDGAGTFFAAYQGEKFISYADAMLGDGMAVLDLGKADESLPVTVYLPEGMKPEIVSLRATQGELLPAPKQPRWICYGDSIAEGWSASEPALSWPAIAGRIHGLDVVNLGYAGAARGEIVSAEQIAALDSPAVISVNHGTNCWTRIPHSATMMMAGMDAFLRVVREGHPGVPIVVCSPVLRPDAEETRNKLGATLEDLREAIEDVVVSRRERGDRDLHLVRGGGVLRAEHLADGIHPGDEGHRIMARAFGDPVAERATRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ03</accession>
    <name>C7QJ03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0190"/>
    <dbReference type="EnsemblBacteria" id="ACU69145">
        <property type="protein sequence ID" value="ACU69145"/>
        <property type="gene ID" value="Caci_0190"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0190"/>
    <dbReference type="HOGENOM" id="CLU_1109838_0_0_11"/>
    <dbReference type="OrthoDB" id="1858493at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981701" evidence="1">
        <location>
            <begin position="35"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="25930" checksum="C14B3D9ECBF6F1FA" modified="2009-10-13" version="1" precursor="true">MIQARSVRLAAVIVLGGAVALATSACGGPMQAGAAAVVQGQRTTDATVQDQVASIVSLVQHNNLQQGDVTDEERSALAKAQINLLVQQAVWQKVADDNGVKVTAADDAKEHSALVEQARGSLQGTKFTGSDNEAVALADAESQQNSSGLAPSSVPVYSHIQALVTAVIDDQATKLRVDPNDQNSLPALQGAILPMLSKASTQIDVKISPRYGSFDASTRQVVAAQTSWIRPTKAQVAAAAAAQAQQQQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ16</accession>
    <name>C7QJ16_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784453.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0203"/>
    <dbReference type="EnsemblBacteria" id="ACU69158">
        <property type="protein sequence ID" value="ACU69158"/>
        <property type="gene ID" value="Caci_0203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0203"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="AVRIMIA"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23388" checksum="27CD304B10FA7ECC" modified="2009-10-13" version="1">MKESSAVRIMIAEDSAILRDGLVQILTKRGHEILAAVPNADELLAAIAVGAPDAVVLDIRMPPTHTDEGLRAALELRRSHPKVGVLLFSQYVETRYARDLFSGQVSGVGYLLKERVADVSEFVEALAKIAAGGTVLDPEVVVQLLGSRPTDALTAREREVLGLMAEGRSNAAIGKKLVLADSSVEKHISNIFTKLGLPPADEDHRRVLAVLKYLGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJD9</accession>
    <name>C7QJD9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ordered locus">Caci_2244</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2244"/>
    <dbReference type="EnsemblBacteria" id="ACU71162">
        <property type="protein sequence ID" value="ACU71162"/>
        <property type="gene ID" value="Caci_2244"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2244"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_11"/>
    <dbReference type="OMA" id="VEICVYE"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="58"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="243"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="59973" checksum="83F61255E331C3A8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJF9</accession>
    <name>C7QJF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FeS assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786475.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2264"/>
    <dbReference type="EnsemblBacteria" id="ACU71182">
        <property type="protein sequence ID" value="ACU71182"/>
        <property type="gene ID" value="Caci_2264"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2264"/>
    <dbReference type="eggNOG" id="COG0719">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026231_6_0_11"/>
    <dbReference type="OMA" id="HAVWIGD"/>
    <dbReference type="OrthoDB" id="422804at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="43324" checksum="570F441B9883DE12" modified="2009-10-13" version="1">MSDPQNLVGASTAAAVTVNEPGAGNRLAGPGTGRAVSQPTDARVERHSSFDPADFPALTGREEDWRFTPLKRLRGLHESPAADGKVAVDVAASEPVLVETVGRDDARLGGAGAPVDRASALAWAGFTEATVITVPQEAEVAEPVRVTLTGSGGTVFGNVLVDVKPFAKAVVVLDYQGSATYSENVQFLVGDSADLTVIALQDWADDAVHLSQQQARLGRDARFQSINVSFGGDLVRLTPRVAYTEPGGDAELLGVYFADAGQHLESRLLVDHSATHCKSRVTYKGALQGQDAHTVWVGDVLIRAEAEQTDTYELNRNLVLTDGARADSVPNLEIETGEIVGAGHASATGRFDDEQLFYLQARGIREDEARRLVVRGFFADVIGRIGIPDVQERLMTKVEEELAGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM9</accession>
    <name>C7QJM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2334"/>
    <dbReference type="EnsemblBacteria" id="ACU71252">
        <property type="protein sequence ID" value="ACU71252"/>
        <property type="gene ID" value="Caci_2334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2334"/>
    <dbReference type="eggNOG" id="COG4581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017075_0_0_11"/>
    <dbReference type="OMA" id="DEFHFYA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021904">
        <property type="entry name" value="DUF3516"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12029">
        <property type="entry name" value="DUF3516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="64"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="245"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="870" mass="96506" checksum="943CCF9F1C1BE2D1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJZ1</accession>
    <name>C7QJZ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4365"/>
    <dbReference type="EnsemblBacteria" id="ACU73229">
        <property type="protein sequence ID" value="ACU73229"/>
        <property type="gene ID" value="Caci_4365"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4365"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_3_11"/>
    <dbReference type="OMA" id="HKQFTEI"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="26"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="316"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="552"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="585" mass="62057" checksum="60EA73B5C6593942" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK07</accession>
    <name>C7QK07_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792974.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4381"/>
    <dbReference type="EnsemblBacteria" id="ACU73245">
        <property type="protein sequence ID" value="ACU73245"/>
        <property type="gene ID" value="Caci_4381"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4381"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573294_0_0_11"/>
    <dbReference type="OrthoDB" id="608093at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="423"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="476" mass="50966" checksum="7E3459111F350513" modified="2009-10-13" version="1">MWVDLNPVTADVEPGAETTVTITVRNTGDIVEEYHLQATGDPGQWGSIEPQTLRLYPGTTGTAQLTFTPPRSAEAQAGPQPYAVKVTPRESRENTFAIEGVLRIAEFADLRAELLPSTTRGWHRGKVRLAVDNYSNVVTSAAVSTTSTNSNLQVDIRTAALRLQPGRAQFSKFSVRPGRLLWFGVKAKHQYNVTVTPSGLGQPVSLQGTYLQSALLPRWLQRLLMFFAAAAAAILALWFGIHPSFATSAQASPQPAAATAPTVIVIQPTPAAPSSTPSPKPTTSSAAPPPPPSSSKSVAPPPASTSKAAAPPPSKTPAPPQPPTQRKTTNILNYSANASVDLNMDKFNDGQQVDIWPTNHSNAQTWTVWSYSDGTMVIQSNDKPESAGTKVLQVDEHNSADVDISDDWNGVAGLKAHLTAPFQVWTFTSIPGHANYGVLKNQQSGTCLASKGSAQWLTTVPCNTGDQTQWFWLFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK13</accession>
    <name>C7QK13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4387"/>
    <dbReference type="EnsemblBacteria" id="ACU73251">
        <property type="protein sequence ID" value="ACU73251"/>
        <property type="gene ID" value="Caci_4387"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4387"/>
    <dbReference type="HOGENOM" id="CLU_265077_0_0_11"/>
    <dbReference type="OMA" id="MTTPPMQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="906"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="950"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1258" mass="121031" checksum="C32888BF5C14C6EC" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK65</accession>
    <name>C7QK65_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6285"/>
    <dbReference type="EnsemblBacteria" id="ACU75139">
        <property type="protein sequence ID" value="ACU75139"/>
        <property type="gene ID" value="Caci_6285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6285"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042774_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="2">
        <location>
            <begin position="336"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="496" mass="48659" checksum="BD2D3768D6A3EB31" modified="2009-10-13" version="1">MDPTPDPLSHQLRTTLRTALTAIPPHPHLHGAPVTETAAHPTLQALQAPDLERPAFAGGLDLGLTAGTLVSEELGRAACGNPYRAGAMAADLGWTAASEDAARVASGAGVASAVGIAGGTGVASTTGTAGAANIARAVEVESGSVVARAGKVVGGAGVASAAEIAGGSAIASAAKIGGGAGVASAAGVAGGSGAAVAAGIAEGSGSAKSAGVEGGSDVARAAGAAGGSGVAQSQGAVVAGVALAGTEALPGARGVIAAPRGDGWELTGTAIVDDAQAALFLVALPDPDAPALVAVPRDAPGVSVLTACWPPVVRFAATPVSAADVVAPTAEALADPLARARVRQAAYLLGIAEGAHRVALDHTGFRHQFGSRLRDLPAVSFPLARALVALRATRAAVYRAAWLVDAEPDSISTEPVIALAMAAETAREVLRLCMQSCGVRAMTAELGLHRYFRLAAAESSRYGEPAALWRIVGAARLREARAAAGREFALAAPVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKF0</accession>
    <name>C7QKF0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8226</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8226"/>
    <dbReference type="EnsemblBacteria" id="ACU77049">
        <property type="protein sequence ID" value="ACU77049"/>
        <property type="gene ID" value="Caci_8226"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8226"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_2_0_11"/>
    <dbReference type="OMA" id="ISLGMEP"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S53" evidence="8">
        <location>
            <begin position="158"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="575" mass="57942" checksum="5E65362163DE0319" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKG3</accession>
    <name>C7QKG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aerial mycelium formation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796787.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8239"/>
    <dbReference type="EnsemblBacteria" id="ACU77062">
        <property type="protein sequence ID" value="ACU77062"/>
        <property type="gene ID" value="Caci_8239"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8239"/>
    <dbReference type="eggNOG" id="ENOG5032UKH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091021_0_0_11"/>
    <dbReference type="OMA" id="CGAEITR"/>
    <dbReference type="OrthoDB" id="1865763at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="20978" checksum="CAC21502A6B9E714" modified="2009-10-13" version="1">MGTHATRLDRVLIAARRPDAEVEALEVAAIRRERGDALREETELSYLRRVLHGRIDIIDAELRRRAEGSAEPLVQSLAAILADDPPANARSPRHMDIGILPDPDPGEYRSQMEERIDAVGPAIVLDLSDGQLGEARLTLKAYEREVSEYRRIAQAVIDRFADELARRYREGQATVDDLLNEEQKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD5</accession>
    <name>C7PVD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0338"/>
    <dbReference type="EnsemblBacteria" id="ACU69291">
        <property type="protein sequence ID" value="ACU69291"/>
        <property type="gene ID" value="Caci_0338"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0338"/>
    <dbReference type="eggNOG" id="ENOG502ZTHM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2057140_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="12334" checksum="4948F21847B9405F" modified="2009-10-13" version="1">MTQTTPGTGDYGPEVAGRPGSTAADYAEDPKERPGFHIGSHTQEMALTITALVLAVVAAAMIGWTGGHVLGGWIALAGIVVGLYAQLTSDTTYERMVNVCAIGIAAVAFAFHLHHGGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH1</accession>
    <name>C7PVH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784622.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0374"/>
    <dbReference type="EnsemblBacteria" id="ACU69327">
        <property type="protein sequence ID" value="ACU69327"/>
        <property type="gene ID" value="Caci_0374"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0374"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="GHLYAPM"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="36068" checksum="F5EFC12615E69B07" modified="2009-10-13" version="1">MDLDLAQVRAFVAAAERLHFGQAAEQLAVSQQALSKRIARLEGELGVQLFLRGGHAVELTDAGRRFLEPARQTLAHGDAAVAAARHVERPLRIDYWGHLFAPMRTLAPVIERVGGAVTVETGPGRDLPGVLDALDRSATDVGFGRVHGVGGGVGSGGGGTRDAAYTHRLVRLEPVDVVISEDHRLAGQSEVRPAELRDSVLWCPAALNRLDFFQRFAEHFDITAESGTANLGIDRFLEQVAADPVRFALIPADLELPERTRVRSLPLVEPTPLYAWSLVWRAADPHPGIEPLLRAFADVAGRSRWLEYQPGRDWLPAGDVSEVWHPAERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM3</accession>
    <name>C7PVM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784674.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0427"/>
    <dbReference type="EnsemblBacteria" id="ACU69379">
        <property type="protein sequence ID" value="ACU69379"/>
        <property type="gene ID" value="Caci_0427"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0427"/>
    <dbReference type="eggNOG" id="ENOG502ZM20">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1892406_0_0_11"/>
    <dbReference type="OMA" id="TRESDPM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981313" evidence="2">
        <location>
            <begin position="22"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="12978" checksum="6BCEBE311B677579" modified="2009-10-13" version="1" precursor="true">MRTRSLLTTLACAAVMVGAGAESAFADATPTTQPSAVPTRSAAPSVPPTTAPTATAMPSAVPSDSARTAAPATPPPTLPGRQVGAVPSGAPNTGEPVAASKGHGEAEAVGASLALLLAGSGSVMVRRRKLKGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH8</accession>
    <name>C7PWH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-phosphoglucomutase family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794987.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6404"/>
    <dbReference type="EnsemblBacteria" id="ACU75258">
        <property type="protein sequence ID" value="ACU75258"/>
        <property type="gene ID" value="Caci_6404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6404"/>
    <dbReference type="eggNOG" id="COG0637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_4_0_11"/>
    <dbReference type="OMA" id="TQTAKVH"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010976">
        <property type="entry name" value="B-phosphoglucomutase_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02009">
        <property type="entry name" value="PGMB-YQAB-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="26893" checksum="45E58E84F2ED3F78" modified="2009-10-13" version="1">MDDATESTKTGLPERIRACLFDLDGVLTETAKVHAAAWKQMFDAYLKSRPGPFVPFDPVADYDRYVDGKTRSDGTRSFLASRNINLPDGSPDDPPGTETINGLGNAKNEIVLKLLDTQGVHVYEGSVRFLKAVRAAGLHRAVVSSSANCANVLKAAGIDDMFEVRIDGVTIAKENLPGKPAPDTYLAAAKKLGIDPDQAAVFEDALAGVEAGRSGGFGFVVGVDRVGQADALRSSGADTVVTDLADLLKQEDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWP3</accession>
    <name>C7PWP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795052.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6472"/>
    <dbReference type="EnsemblBacteria" id="ACU75323">
        <property type="protein sequence ID" value="ACU75323"/>
        <property type="gene ID" value="Caci_6472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6472"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_5_11"/>
    <dbReference type="OMA" id="APEAWIR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="19765" checksum="EDB3B6FB55CB8FCC" modified="2009-10-13" version="1">MRDSQSFDDFYLASVRRVTSYVHAWTGNLADAEDIVQEAFAKAWQHWGKVGGYADPEGWVRTVAFRHRVSVWRKATTRLTAHRLHGPPGDEPEVSPDYVAIIAALRKIPEAERRAIVLHHIVGLTVEDVAAETGVAQGTVKARLHRGRHRLSGHLTIDDPVGRSQESIRKEMHGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT7</accession>
    <name>C7PWT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase AAA-2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796919.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8371"/>
    <dbReference type="EnsemblBacteria" id="ACU77194">
        <property type="protein sequence ID" value="ACU77194"/>
        <property type="gene ID" value="Caci_8371"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8371"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_1_11"/>
    <dbReference type="OMA" id="ERMKAVM"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="423"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="810"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="850" mass="93498" checksum="F518A5FEB6B32210" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWV6</accession>
    <name>C7PWV6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ordered locus">Caci_8390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796938.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8390"/>
    <dbReference type="EnsemblBacteria" id="ACU77213">
        <property type="protein sequence ID" value="ACU77213"/>
        <property type="gene ID" value="Caci_8390"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8390"/>
    <dbReference type="eggNOG" id="COG0461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074878_2_1_11"/>
    <dbReference type="OMA" id="YVNCKPV"/>
    <dbReference type="OrthoDB" id="1280396at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="72"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="133"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="191" mass="19685" checksum="5BDA5774D227CCF1" modified="2009-10-13" version="1">MPNAPIVAHPSPARDALLKEIQAKAVVRGEVTLSSGLKADWYLDLRRITLDGTAAPLVGTAMLELTAELDFDAVGGLTMGADPVATAMLHAAAAGGNGRTLDAFVVRKAAKAHGMQRRIEGPDVAGRRVLAVEDTSTTGGSPLEAVRTLREAGAEVVAVATIVDRATGAAEAIAAEGLPYYTVYTLGDLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX07</accession>
    <name>C7PX07_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796989.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8441"/>
    <dbReference type="EnsemblBacteria" id="ACU77264">
        <property type="protein sequence ID" value="ACU77264"/>
        <property type="gene ID" value="Caci_8441"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8441"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026494_1_1_11"/>
    <dbReference type="OMA" id="RTSRDQY"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981327" evidence="3">
        <location>
            <begin position="30"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="297"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="43490" checksum="027858A3058F0720" modified="2009-10-13" version="1" precursor="true">MRGRGHGRRATLVTATVLTVALLGAAAHADPGTPVVPGQGDIDRAKAAVSDRQSAAAQIQQALDAANGRLHSLQARAGLAAEAYDTAVAQAAAAARAADAARTRAATTLDAQHQAEQRLGAFAAATYRQGPDMAAALTLLRAGSLHDFAVQRQALANHDAAEALAVTDARQATTAATAARRGADQTAAEQRRAEAQAQSALGAARTAASDAQSQVAGIQAQQDGLLRQLAAAQGVEVGLERQREAGLAALAAQQAAARQAAAAAASPAGAGHTQSHTSSNGRGGTWTPSASVSAGPVPYAQGAVRQMLAYIYAQLGKPYVWGGAGPDVFDCSGLAMRGLEAGGWSFPHPAQWQYLAMHSLSYNQLRPGDLVFWAEDPSDPHTIYHEAIFIGNDRIIQAPHPGGVVEQQSLWINGPPSFYGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX95</accession>
    <name>C7PX95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MazG nucleotide pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0496"/>
    <dbReference type="EnsemblBacteria" id="ACU69446">
        <property type="protein sequence ID" value="ACU69446"/>
        <property type="gene ID" value="Caci_0496"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0496"/>
    <dbReference type="eggNOG" id="COG4696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097934_1_0_11"/>
    <dbReference type="OMA" id="GPNYFKP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11530">
        <property type="entry name" value="NTP-PPase_DR2231_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033653">
        <property type="entry name" value="NTP-PPase_DR2231-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023292">
        <property type="entry name" value="NTP_PyroPHydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="16985" checksum="77F39A227DEB1D77" modified="2009-10-13" version="1">MTVESGIREAGRLCVEPGLSDAMRAVAAFHTAFDLPRQPVPSTDVSTELAQLRVDLLVEEVGEFADATSKRDLTAMADALGDIIYVAYGAAVTYGIDLDAVLMEIHRSNMSKLGSDGRPVLRQDGKVLKSSSYRPPDVARVLAEQSELTVVSEAIDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXJ9</accession>
    <name>C7PXJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding region ATPase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2534"/>
    <dbReference type="EnsemblBacteria" id="ACU71452">
        <property type="protein sequence ID" value="ACU71452"/>
        <property type="gene ID" value="Caci_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2534"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021841_2_1_11"/>
    <dbReference type="OMA" id="RSANEPW"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="436" mass="45267" checksum="41C783462D6E4872" modified="2009-10-13" version="1">MGTALALCGAVVGWCVRVLITHRRVAAARVRCDAAEAENARWRQAHSGQTREPVEALAVLRDRAAAEGGSAIGSSANGIRADSIRTDGLRADGMRTDGSPDFAERAFVNIGRRVQAIVHKQLADLSEMQERHGGDPAVFADLMRLDHATALVGRFADSLVVLAGERPGRQWSEPVPVFSVLRGAMARIVDYRRVELAAAPEVELAGTAVEAVVHALAELLDNATRYSPPDSRVILTGRRTSAGVVIEVVDAGVGLAPQAAEHVARVLADPGAAGMDLADISGSPRLGLAVIGRLAHTVGFQASVRPSAAGGVKAQLLVPNELVLAPRGAADSPAVPRVPSQTGRAAQDASEPGVRPNGTPDGRPGGLPQRKRRPPTVPVTTTPVVAKTARARPESPSTDSGPAATDSGPGQWLDAFRGDPPGSPGDDTDRERGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXM0</accession>
    <name>C7PXM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2555"/>
    <dbReference type="CAZy" id="GH95">
        <property type="family name" value="Glycoside Hydrolase Family 95"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71473">
        <property type="protein sequence ID" value="ACU71473"/>
        <property type="gene ID" value="Caci_2555"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2555"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004617_2_2_11"/>
    <dbReference type="OMA" id="WANWYMG"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016518">
        <property type="entry name" value="Alpha-L-fucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027414">
        <property type="entry name" value="GH95_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14498">
        <property type="entry name" value="Glyco_hyd_65N_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007663">
        <property type="entry name" value="UCP007663"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982289" evidence="1">
        <location>
            <begin position="40"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hyd_65N_2" evidence="2">
        <location>
            <begin position="63"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hyd_65N_2" evidence="2">
        <location>
            <begin position="121"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="804" mass="86466" checksum="1CB727078CB223ED" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP0</accession>
    <name>C7PXP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2575"/>
    <dbReference type="EnsemblBacteria" id="ACU71493">
        <property type="protein sequence ID" value="ACU71493"/>
        <property type="gene ID" value="Caci_2575"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2575"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_3_11"/>
    <dbReference type="OMA" id="RAMFFEG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="19553" checksum="412658231E25D7A1" modified="2009-10-13" version="1">MASALAVLAEEGVAGLTARTVARRASASVPAIYEVFGDKGGLIREVYFEGFRLLGAQLAQVPPTPDPLEALLNVCESFRQFVLANPVLAQTMFSRPFVDFSPTTDDNKAGLSVSKVFVRRTRAAVEAGRLVGDPTDIAHLFFACVEGLAAAESAHRLGGSKAVVDRRWRLALDTLVRGLAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXS0</accession>
    <name>C7PXS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786816.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2606"/>
    <dbReference type="EnsemblBacteria" id="ACU71523">
        <property type="protein sequence ID" value="ACU71523"/>
        <property type="gene ID" value="Caci_2606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2606"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064284_0_0_11"/>
    <dbReference type="OMA" id="AGREAWF"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="29099" checksum="A613A0DB5CED4886" modified="2009-10-13" version="1">MSAPNQAPAKRFRWDGESLVPAPGDGARPEVIDSWLVADGAWLAPERHAERFADAVHRLHGIDPATSRALVSAAPPLIPTTGTWFPRVEYSPTDGFHLLVRPAPPLGSTVRLWTAPEPDTRLHPTIKGYDLPLLNDLREQAHAAGADEPLLVDAQGHVLEGASTSILWWRDGALCAPPESESVLTSVTRAVLVDLAEAAAIPVRHEQARPRDLDGLEIWAVNALHGIRPIVPWPGSPVLPGPATQAPRWRRELQDKRSINDNAPKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXX9</accession>
    <name>C7PXX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4577"/>
    <dbReference type="EnsemblBacteria" id="ACU73439">
        <property type="protein sequence ID" value="ACU73439"/>
        <property type="gene ID" value="Caci_4577"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4577"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1188227_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="3">
        <location>
            <begin position="110"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="23830" checksum="0DFA50D3C276D1D2" modified="2009-10-13" version="1">MGQIVVTESLTLDGVMQAPAGPKQTDGNPFTEHLRKVQKYVVSATMAESLPWANSTVVRAKRDGAGSGEGASASASAGGGGVPAAVAALRDGIEQDIATRPEEMAAMTRYLLSIYQPDGPLPSEERLADIGRELDALNAELREAGSWVFDGGLHPASTATVLRPGPASGSGSGSSSGSGSNEVLITDGPFADSKEHLGGIKIIDAPDLDAALGWAAKLTRAVGLPVEVRPFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY16</accession>
    <name>C7PY16_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793205.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4615"/>
    <dbReference type="EnsemblBacteria" id="ACU73476">
        <property type="protein sequence ID" value="ACU73476"/>
        <property type="gene ID" value="Caci_4615"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4615"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056341_0_0_11"/>
    <dbReference type="OMA" id="EPQMQAI"/>
    <dbReference type="OrthoDB" id="250058at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045641">
        <property type="entry name" value="MmpI-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19307">
        <property type="entry name" value="PCLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="103"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="477" mass="52267" checksum="2A9F9F03080002A7" modified="2009-10-13" version="1">MTITPDRTAEQAPEDPAATDSPLSLSTDAARNLATTTKTQPQMRGITSRWLLRRLPWEEVSGGTYRVNRRLSLAVGRGRVAVVQSGADDIRIVPETLREIPVMRGFADDAVLAELAGLFTPRDFAPGEVIAEAGHPVDEVFILAHGRVERSTIGAYGEPTLLGVLTDGAHLGDEVLLQADPLWSATVKATTAGTLLAMPMADFARIREGNADLREHIDAFVARTDRAVNSKGEAVVDVTSGHEGEVELAGTYVDYELSPREYQLSLTQTILRVHSRVADLYNDPMDQVKEQLRLTIEEIRERQEWELLNNREFGLLHNTDYDQRISTWSGPPTPDDMDDLLAMRRSTTMFLAHPKAIAAFGRECSKRGLYPDPVLIDGHAVPAWRGVPIYPCGKIGVADGHTSSIVAMRLGREQQGVVGLRQTGIPDEYEPGLNVRFMGITDKAIIKYLVTAYYSTAVLVPDAIGILENVDVAAPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYE7</accession>
    <name>C7PYE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6591</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795166.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6591"/>
    <dbReference type="EnsemblBacteria" id="ACU75437">
        <property type="protein sequence ID" value="ACU75437"/>
        <property type="gene ID" value="Caci_6591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6591"/>
    <dbReference type="eggNOG" id="COG0659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_13_0_11"/>
    <dbReference type="OMA" id="TECQKIG"/>
    <dbReference type="OrthoDB" id="751256at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="442"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="576" mass="60364" checksum="57712D08A73B7C3B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL5</accession>
    <name>C7PYL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fibronectin type III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8514</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8514"/>
    <dbReference type="EnsemblBacteria" id="ACU77337">
        <property type="protein sequence ID" value="ACU77337"/>
        <property type="gene ID" value="Caci_8514"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8514"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_344104_0_0_11"/>
    <dbReference type="OMA" id="YIPWAWL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="519"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="612"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="385"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="822" mass="82101" checksum="C0463887B285DD03" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN5</accession>
    <name>C7PYN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797082.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8534"/>
    <dbReference type="EnsemblBacteria" id="ACU77357">
        <property type="protein sequence ID" value="ACU77357"/>
        <property type="gene ID" value="Caci_8534"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8534"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_3_11"/>
    <dbReference type="OMA" id="MANGENI"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="23098" checksum="6E2BB9D077FEBD53" modified="2009-10-13" version="1" precursor="true">MTDQAHHPRQRRHGEELEAALLEAAWQELVETGFTKLTMESIATRAKTGVAVLYRRWPNKDDMILAAIRHYGTTHPVAVPDTGNLRDDMVAFLTGVSVSRVSFAAIISATFAGLRDSTGMTPAELRERVMSNASRWSEQLLARAQDRGEIDLDAIPPAVLSMPFDLIRHEMLMTYKPIAPERVIEIVDDLFMPLVTINRRKNECAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYP0</accession>
    <name>C7PYP0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN_8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8542"/>
    <dbReference type="EnsemblBacteria" id="ACU77362">
        <property type="protein sequence ID" value="ACU77362"/>
        <property type="gene ID" value="Caci_8542"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8542"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645408_0_0_11"/>
    <dbReference type="OMA" id="DYLVWEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041578">
        <property type="entry name" value="PIN_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18476">
        <property type="entry name" value="PIN_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_8" evidence="1">
        <location>
            <begin position="45"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="49303" checksum="6020F776CBC3B024" modified="2009-10-13" version="1">MTVLDGDAAEPRNPVPAKQGGLFDGFEGYRTPTDADYQAVLASGLVVPDANVLLNLYRYTEEAREDLLSVLTKLGDRLWVPHQVLVEFWRNRESALSDPETSAANTAGELAKLRVQALGAIRNWGHRVALPAEELSKLCDDLSESFDVAEGAIKGLASAGSRGRWNTNDDPVILKLTTLLDGRVGVALNGEEYERAVKEGLQRVKDRRPPGYMDKAKDGDNAAGDYLVWEQVLIEAGRQGSDVLFVTGDVKEDWWRRDRGQTRGPRLELVQELLVRGGGHLYMMQPSRLLEIAGLSLDVEVREGSIEDVERVNRLHAEDLDFGGWSTDALQELFYHLEDEGYGERVSVIRWAAENDGIASREAVYGLGGYAEERQLKGFTRPVSRIAKEFRRLGIISPNAVDILETVYDPAFSYVQAAGFRVHPSVVPLILQLSEEVAEADQEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYQ1</accession>
    <name>C7PYQ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797098.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8553"/>
    <dbReference type="EnsemblBacteria" id="ACU77373">
        <property type="protein sequence ID" value="ACU77373"/>
        <property type="gene ID" value="Caci_8553"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8553"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_8_0_11"/>
    <dbReference type="OMA" id="DGWLESR"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26837" checksum="0AC0B97FFACD38F6" modified="2009-10-13" version="1">MPFESAPPKYARVVTGLQERILDGRYPAGSMLPSEEQLVNEWDMSRTTIIRALQILSRDGWIESQQGKGRFVRGRPAAMDQRFRPSRNALEQSETSGSRLVDVGHVIAPNAVAAALNLKKNEAVLMRRRLVVRDDEPDELVTSYFPLDLAHGTALGAETLMSEGARYQVESRNKIRYDHITERIAARLPSGEEALLLGLPSKRTPVLAVTVTAFAASGRPVQLAELVLPGDRHELEDTYPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX7</accession>
    <name>C7PYX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WGR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0596"/>
    <dbReference type="EnsemblBacteria" id="ACU69533">
        <property type="protein sequence ID" value="ACU69533"/>
        <property type="gene ID" value="Caci_0596"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0596"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006807_1_1_11"/>
    <dbReference type="OMA" id="VAPPWTR"/>
    <dbReference type="OrthoDB" id="214704at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4132" evidence="1">
        <location>
            <begin position="855"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1130" mass="123825" checksum="4FE0792E3CD6E88B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZD1</accession>
    <name>C7PZD1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786881.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2672"/>
    <dbReference type="EnsemblBacteria" id="ACU71588">
        <property type="protein sequence ID" value="ACU71588"/>
        <property type="gene ID" value="Caci_2672"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2672"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097561_0_0_11"/>
    <dbReference type="OMA" id="LALCEPR"/>
    <dbReference type="OrthoDB" id="993828at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="28537" checksum="70818BA366D9D69E" modified="2009-10-13" version="1">MDTVIVQPSDPRTRPPGLLRLGPGDVLTFGRGAPNAPVGLELAGDGVSRRAGELAAVDDHWRISNFSRTTTYVVENLEGAGEHVKVAPGRIGAPIPFEISRVVLPVADGFVGFTVYAPQHSYSDSYSDLTGSEATGTAAGTGARAPGAGERTVLPFSLDPTAKYFLVLLALCEPRLREASAVAIPNAGDVVERLRPLPSCADLTKSAVNYHIDYLATTKLRVREREGTDGAARMDWKREAIVALALRFDLVRDEHLRMLPARRAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ4</accession>
    <name>C7PZZ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6641"/>
    <dbReference type="EnsemblBacteria" id="ACU75487">
        <property type="protein sequence ID" value="ACU75487"/>
        <property type="gene ID" value="Caci_6641"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6641"/>
    <dbReference type="eggNOG" id="ENOG5033U6E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1208030_0_0_11"/>
    <dbReference type="OMA" id="RCAASHI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981356" evidence="1">
        <location>
            <begin position="28"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="22624" checksum="301AFB9D766DA2A5" modified="2009-10-13" version="1" precursor="true">MHSLKAFAVAAAVAALATVAVVGTASAAAAPVSVLTYGAPGPGGPNVAPGQVLTGNLQPGTKATFLTAPGGGVGTFCSVSNIGVQVLANPTAPGVAVSKLAALGFGGCVSTIPGSTVLSVTENNLPNNNVLFNDSAGFPVQFVPAGAPVQLTIVESVPGAVLNCVWQPVGSIYQGNYANPGNRLIVLNQKIQLMSGPPGPCGGTLQFMSFTYQPVVDSSVPGSPPVFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q084</accession>
    <name>C7Q084_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6731</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795306.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6731"/>
    <dbReference type="EnsemblBacteria" id="ACU75577">
        <property type="protein sequence ID" value="ACU75577"/>
        <property type="gene ID" value="Caci_6731"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6731"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="IGTWQVF"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035277">
        <property type="entry name" value="MalF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="37580" checksum="EA95B8F37108E624" modified="2009-10-13" version="1">MSRTRSQEDRRQALAGWLFVSPALLGLIVFLVVPIVLALYVSFTNWDGLSNPLGGDVKWVGLHNYQQLLTHDGLTRTTFAGALRNNFWFVLFVVPTQTALALWLAVLVNNKYLRGRGFFRTAFYFPSITSSIAITLVFLFLFQGGGAVNGILNWFGVKGPNWLADPRGVVHVWLSGIGVSKPPGWTRHSVMGQSVWDWFSGPSIAMMVIIILVIWTTAGTFMLMFLAALQNVNEDLYEAGELDGAGGWQRFRYITLPSLRPTLLLVLTLGLIGTWQVFDQIYLTGNNPATRTPAFMSFDQSFQNNHFGIGSAIAFLLFALIMGLTLLQRRLIPEEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0E4</accession>
    <name>C7Q0E4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8662</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797201.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8662"/>
    <dbReference type="EnsemblBacteria" id="ACU77477">
        <property type="protein sequence ID" value="ACU77477"/>
        <property type="gene ID" value="Caci_8662"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8662"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107911_0_0_11"/>
    <dbReference type="OMA" id="IAWRAYR"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="22649" checksum="5A02F716AA3D0988" modified="2009-10-13" version="1">MSPVNSKQAEKARQTRKRVLTAAGELFVEHGYGATTLQQIAERADVAVQTIYFVFRNKRTLLKELADVTVAGDDEPVPTMERPWFTAAMAAPTAEEHLRAHVAGAVSVNARVSALLEVIRTAAALEPELDALRRTGDEQRYTVQHTAAQALMAKPGARPGLTAEHAADLLYATLGPEMYLLLVRDRGWSAGRFADWADASLRSQLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0L3</accession>
    <name>C7Q0L3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0706</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0706"/>
    <dbReference type="EnsemblBacteria" id="ACU69641">
        <property type="protein sequence ID" value="ACU69641"/>
        <property type="gene ID" value="Caci_0706"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0706"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="VRWGRVS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="129"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="20993" checksum="05459C717E9AEC57" modified="2009-10-13" version="1">MCNTGTGVRVGTGGMFNEGSAVAMAKHDEEFLEFASARTSHLFRTAYLMSGDWHQAEDLVQETLGKVYSVWGRKRRIENPDAYAQTVLTRTFISARRKRSSRELPSSQLPEGEFHEADTSLRMTLLEGLAALPPKDRAVLVLRFWEDRSVEEVAHIMGASSGAVRTRTNRALTRLRGALGDLLPDLALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Z4</accession>
    <name>C7Q0Z4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71669">
        <property type="protein sequence ID" value="ACU71669"/>
        <property type="gene ID" value="Caci_2756"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2756"/>
    <dbReference type="HOGENOM" id="CLU_908175_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="68"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="32586" checksum="F7E6513CF308257C" modified="2009-10-13" version="1">MTMTMTTTTTPTPTTTQATASRVRPRTRKPPKPLRPLPEPYRLTWWTRPGQPTFDDVCDALAFQHFILDELLQPVRESQWRAPTPSARWRVADLLGQVIASAEHVVQTAHASQPRRRAPVLDALDWYQGSGSLSTLTVEQARAVAGSAPGARFAELAELAELARLHRVAASTAAAILRSGEPGLVLRGAAGGITLADYTVTRLVGAVVHGLDLADALGRPGRAHGPAVRLVGGYFAALGERRGPAGSRSAPIALGTDGSLIALHAKRPATIVPAISWIQAATGRRPAGRLLPDSHQWLADLLPLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q131</accession>
    <name>C7Q131_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma-factor antagonist</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786999.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2793"/>
    <dbReference type="EnsemblBacteria" id="ACU71706">
        <property type="protein sequence ID" value="ACU71706"/>
        <property type="gene ID" value="Caci_2793"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2793"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026775_0_0_11"/>
    <dbReference type="OMA" id="TQVAQHI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025751">
        <property type="entry name" value="RsbRD_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14361">
        <property type="entry name" value="RsbRD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="143"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="28806" checksum="5F5A8E89B18CCA6D" modified="2009-10-13" version="1">MMTARRDDLTAGWIEVVARTLASRISRAELDRELHELYGAVVEALGSGLDTDDEAWSEVRALLVELSRNRARQGFTPAETAISVFALKAGLEQSVEEGSAADVAAYLALSRLTDSLGMFTVDSYAETREQIISSQTEELLELSTPVVKLWDGVIGVPLVGTLDSARTQVVMEKLLQALVDTGSAHAIIDITGVPAVDTEVAQHLLKTVVAARLMGAECIVSGIRPQIAQTIVALGIEFGDIITKATLADALRHALRGAGETAAGRGTGASRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q189</accession>
    <name>C7Q189_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2855"/>
    <dbReference type="EnsemblBacteria" id="ACU71764">
        <property type="protein sequence ID" value="ACU71764"/>
        <property type="gene ID" value="Caci_2855"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2855"/>
    <dbReference type="HOGENOM" id="CLU_2435453_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9532" checksum="7162D49522B363D5" modified="2009-10-13" version="1">MTTATVGAHTRPPVNRWTPAKRGFAAWRRKAAIRVRGASAHIVGPEATVRKLVMTATALGFLDAAAWDFKTIAGLAATGISVAILNECMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1J5</accession>
    <name>C7Q1J5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FMN_red domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793453.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4864"/>
    <dbReference type="EnsemblBacteria" id="ACU73724">
        <property type="protein sequence ID" value="ACU73724"/>
        <property type="gene ID" value="Caci_4864"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4864"/>
    <dbReference type="eggNOG" id="COG0655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082329_0_0_11"/>
    <dbReference type="OMA" id="TYWVGEA"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="21303" checksum="69D2207E4101F035" modified="2009-10-13" version="1">MKALVINCTLKPSPEPSNTHALAQVVGDELQSKGVEVEYLRAVDLTLLPGVKTDQGSGDEWPGVHEKLLQAAILVIASPTWVGRPSSVAQRVIERMNAMIGETDSQDRPVAFGRVAGVVVTGNEDGAHHVVSEIAGALGDIGYTIPGNAWTYWHLGPGKGPDYLDAKRGHDWSDETGRTMAANLHIAAKALAADKDAAPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1R1</accession>
    <name>C7Q1R1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6767</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795341.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6767"/>
    <dbReference type="EnsemblBacteria" id="ACU75612">
        <property type="protein sequence ID" value="ACU75612"/>
        <property type="gene ID" value="Caci_6767"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6767"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_4_11"/>
    <dbReference type="OMA" id="IPITRAH"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="34"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="351"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="385"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="589" mass="64226" checksum="AA849966BF3FC4B2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q274</accession>
    <name>C7Q274_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8798"/>
    <dbReference type="EnsemblBacteria" id="ACU77611">
        <property type="protein sequence ID" value="ACU77611"/>
        <property type="gene ID" value="Caci_8798"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8798"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_2_0_11"/>
    <dbReference type="OMA" id="WETGWGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S53" evidence="8">
        <location>
            <begin position="182"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="610" mass="63181" checksum="BCDFF4A85C2EB8E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q289</accession>
    <name>C7Q289_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thiC</name>
        <name evidence="13" type="ordered locus">Caci_8813</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8813"/>
    <dbReference type="EnsemblBacteria" id="ACU77626">
        <property type="protein sequence ID" value="ACU77626"/>
        <property type="gene ID" value="Caci_8813"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8813"/>
    <dbReference type="eggNOG" id="COG0422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013181_2_1_11"/>
    <dbReference type="OMA" id="TWELFRD"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="12">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="317"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="358"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="553"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU77626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="601" mass="65708" checksum="9ABEBCBD09AF047B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q295</accession>
    <name>C7Q295_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8819"/>
    <dbReference type="EnsemblBacteria" id="ACU77632">
        <property type="protein sequence ID" value="ACU77632"/>
        <property type="gene ID" value="Caci_8819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8819"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1286889_0_0_11"/>
    <dbReference type="OMA" id="GLTMTQY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="22705" checksum="118A4703A533BE58" modified="2009-10-13" version="1">MKGFAGYAHTMTAVEQRLGHKVKSLEQELSGAKDAVLRPMGVTVPQYTALLVINDEPGISGAELARRCLVTPQTMTTVLGNLTLKGYIERRSVPGQGRAMETTITTAGKRILAKADKEVLAVEKTLAGTMAVKDQATFAKLLDQARAPFTKEEAAPKPVKRAVRTTAKKTAKKAPAKKTAAAKAAPAKKAAAKKTVKKAAAKKTAKKTAKKTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2C4</accession>
    <name>C7Q2C4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglycosylase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785061.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0832"/>
    <dbReference type="EnsemblBacteria" id="ACU69766">
        <property type="protein sequence ID" value="ACU69766"/>
        <property type="gene ID" value="Caci_0832"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0832"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_992848_0_0_11"/>
    <dbReference type="OMA" id="GAMTHAK"/>
    <dbReference type="OrthoDB" id="2027419at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="28329" checksum="B990991D4A21CD5D" modified="2009-10-13" version="1">MSGISGSGSGRHVASHAKPGAMTHAKGKVKTAAAVTSVLAVSGGVATAFHLHQDGLRNSAEAASQDSNTSAAAAAANALAARAGTNAANRDLQRPSLGQSSTPGTPSSSQPSSAQSPSTPASSSSSTPAPPASSSSTPIPLPSKPLTTPTPTKTSTPIPTKTTTTPTSSSSSSSSSTTNMGYNATPAQAKAMAESIVPSSQFLCFSNIIERESSWNVHATNPSSGAYGLGQALPGDKMASMGSEWRNSALVQIKWALSYMTGRYGSPCAAWAFWQAHDWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2H0</accession>
    <name>C7Q2H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785107.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0879"/>
    <dbReference type="EnsemblBacteria" id="ACU69812">
        <property type="protein sequence ID" value="ACU69812"/>
        <property type="gene ID" value="Caci_0879"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0879"/>
    <dbReference type="eggNOG" id="COG3361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081757_1_0_11"/>
    <dbReference type="OMA" id="HFLTARW"/>
    <dbReference type="OrthoDB" id="1231841at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018644">
        <property type="entry name" value="DUF2071"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39186">
        <property type="entry name" value="PTHR39186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09844">
        <property type="entry name" value="DUF2071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="28206" checksum="5F9AC0F3F1106F0D" modified="2009-10-13" version="1">MSPAEAAKAAAPEPVTADAPRLPSRPLMTQSWLDATFLHWAADPALVAPLLPAGVRPDVIDGATYVGLIAFRMHRIGWWPLPGMPYLGTFPETNVRLYSVDAAGRRGVVFRSLEASRLLPVATARTAFRLPYRWARMSAYRSGDEYWYGSRRREPGLPPSRSIIGVRVGPAIETPSALDHFLTARWRLHFTLAGRTVHMPNAHPRWPLHHAELLACEEDLVAAAGLPGVASGPPDSVLFSPGVAVRFARPYAVDRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V1</accession>
    <name>C7Q2V1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787136.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2934"/>
    <dbReference type="EnsemblBacteria" id="ACU71843">
        <property type="protein sequence ID" value="ACU71843"/>
        <property type="gene ID" value="Caci_2934"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2934"/>
    <dbReference type="eggNOG" id="ENOG502ZDP0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2245070_0_0_11"/>
    <dbReference type="OrthoDB" id="2194665at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="11218" checksum="36C80B53D7A80D02" modified="2009-10-13" version="1">MTTTLTPYQVLALPMPENDADATTIGDYLIKLLATLWDEKEGFDGKKPFGNSDWDGDLVVALIQAGAIEGELDEDRCIEFCDDDAAEELIAAAIQALGTGRDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2W8</accession>
    <name>C7Q2W8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71860">
        <property type="protein sequence ID" value="ACU71860"/>
        <property type="gene ID" value="Caci_2951"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2951"/>
    <dbReference type="HOGENOM" id="CLU_2011151_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="14097" checksum="5AE649F4C1890DA6" modified="2009-10-13" version="1">MSTYEWTIGMPRSLTHHREARIEHSFDTVVNVTADPPNLEILPHAPADTDVAKWVVAWKVVHFRTRDTWQVGVLRAWILLHDGWWVAHIDHAGGGMHNDWQQSTWVVYDTALVVPVNPVPDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E0</accession>
    <name>C7Q3E0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795433.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6866"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75705">
        <property type="protein sequence ID" value="ACU75705"/>
        <property type="gene ID" value="Caci_6866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6866"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016116_0_0_11"/>
    <dbReference type="OMA" id="GYILVHG"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981396" evidence="3">
        <location>
            <begin position="38"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="350"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="51805" checksum="BFDACB41EBA18520" modified="2009-10-13" version="1" precursor="true">MTVARLKKTMASRILTGLTGALLLSAAVVGPVPITHAASASTFSPGAAWKDQNGNALQMHGLGIVKSGSTWYAFGEDKKGESSSDTSFRAIPCYSSTDLQTWTYHSSALSKQASGDLGPNRIVERPKVIYNASTRQYVMYMHIDSPSYSEAKVGVATSSTPCGPYTYRGSFQPLGFQSKDEGLYQDTDGTAYLMSRDPQHGLRIDRLSADYLSVASNVALFPDLEAPAMMKSGGRYYLLASHLSGWKTNDNVYAGATSLSGPWTSFTDFAPAGTSTYNTQTANIIPVSGSSGTTFIYAGDRWNSSDLGNSPLVWLPITVSGTTLNVGWFNSWSLDVSAGTWTAGSSVPSAAAHVLASGADNQVVDVAKASKNDGAAIDQWPATGGANQSWNLHRASGNVFTVVSAESGECLTVSGASTSAGGALIQWPCSSAADQLWAFDAVGDYASSSNTSYIVRNLNSGLVVDIPKNSTVAGTALDQWTGNGGANQVWRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3K4</accession>
    <name>C7Q3K4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795497.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6936"/>
    <dbReference type="EnsemblBacteria" id="ACU75769">
        <property type="protein sequence ID" value="ACU75769"/>
        <property type="gene ID" value="Caci_6936"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6936"/>
    <dbReference type="eggNOG" id="ENOG5032TZU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142708_0_0_11"/>
    <dbReference type="OMA" id="TIRFFAM"/>
    <dbReference type="OrthoDB" id="1702154at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982762" evidence="1">
        <location>
            <begin position="28"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16719" checksum="1718F501AF33B841" modified="2009-10-13" version="1" precursor="true">MQRTLKAAIGALAAVAMIALTAVPASAASASRAKDSDAAYFVMTDVTHEQFVVRLDDPTEIEHARDLLSGRTTDRPHVIGRITSRTAPYNPRWSYHLTPSTVHFFDFAIEVCDATIPYVEEHLDEAGGAFLPGYVWCDWSSRLVKEISAVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W5</accession>
    <name>C7Q3W5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8910"/>
    <dbReference type="EnsemblBacteria" id="ACU77723">
        <property type="protein sequence ID" value="ACU77723"/>
        <property type="gene ID" value="Caci_8910"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8910"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048478_2_0_11"/>
    <dbReference type="OMA" id="EFYLAHR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="29"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="28050" checksum="B65146D7CCF9CF1A" modified="2009-10-13" version="1">MTPGVRPEAGTERATLILAPNADPMTLDGTNTWLLAEPGARGAVVVDPGPLDEGHLQLVLATAEERELRIGLILLTHGHFDHSEGAPRLAELTGAPVRALDPRFRLGEEGLAGGDVVDVDGLRLDVVATPGHSGDSMCFVLPDDRAVLTGDTILGRGTTVVAHPDGRLGDYLDSLRRLRDLTAAHEVETVLPGHGPVPADALGVVEFYLEHRRQRLEQVRAAVAAGDESAADVVARVYADVDPAVRFAAEMSVRAQLEYLHDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4C2</accession>
    <name>C7Q4C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1056"/>
    <dbReference type="EnsemblBacteria" id="ACU69982">
        <property type="protein sequence ID" value="ACU69982"/>
        <property type="gene ID" value="Caci_1056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1056"/>
    <dbReference type="HOGENOM" id="CLU_745326_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="37765" checksum="ECE136F38C906CDF" modified="2009-10-13" version="1">MSDELDNDFTDELATSLRAAAAETPQTTDPYGPVGIAVSRDRKRRTAIGASLAVVAVLGAAIGIGDEVGRGSSASVQSSGAAPGSDRTPAAKPTPAAPTPSATPSTSAAKAGDPPTPQTSPSWSMPSTSQPMMLGWPSDFSLFPGYKTATTEAVPTVNAIVHAYGEPVDQGTRNVLDNLVGSFKLCGYSLSSYTFTLRWAGDLAHSGGNGAALVDVSHGGATYRMVGLDTYKGVWLMLPTTIDTTTAARIDAAALAELDQPAQEFYEPVVAAPGSKVTVSGTNTDGLTPPTPFQSSTVTVGASGVAEVPLDSGNPGMYPTLTEVKIVRPDGTTATAPLLGGTSAAQEQSARELLPANTVCPGMTPEVPLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4F2</accession>
    <name>C7Q4F2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3012"/>
    <dbReference type="EnsemblBacteria" id="ACU71921">
        <property type="protein sequence ID" value="ACU71921"/>
        <property type="gene ID" value="Caci_3012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3012"/>
    <dbReference type="HOGENOM" id="CLU_2877528_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="6855" checksum="E7DAE6F09613FDF7" modified="2009-10-13" version="1">MIEDRPRWASLTAEQREIATTLYLRAQELIDSGMSIAEAMETAAIHAGHVDPLLSNVTTTEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Q1</accession>
    <name>C7Q4Q1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3111"/>
    <dbReference type="EnsemblBacteria" id="ACU72020">
        <property type="protein sequence ID" value="ACU72020"/>
        <property type="gene ID" value="Caci_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3111"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_320490_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="407"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="497"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="885" mass="89610" checksum="CF64449998F1CC67" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S6</accession>
    <name>C7Q4S6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793603.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5014"/>
    <dbReference type="EnsemblBacteria" id="ACU73874">
        <property type="protein sequence ID" value="ACU73874"/>
        <property type="gene ID" value="Caci_5014"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5014"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076888_0_0_11"/>
    <dbReference type="OMA" id="HGDAWSR"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="31002" checksum="2EDA79EC269AFFEB" modified="2009-10-13" version="1">MVRRLPLDVRTDLVHGGRWTSLRGADREWLWQNPDAAGRSSVLPGQSFVDAGGLEECVPTVRGTPDHGDAWSRPWRSNGGTEVCQSPDFVLTRRIEADGDSLRVHYVLRAEPGYRFLWAAHALLDVSEQAVLRASDSTATRVYPDAGARYAEGLWPAPWQEVRLDRLGPDDGTALGAILTGCRGATVVDGADALSFALRADPGVPVSLALWRNLRGFPARHPYRSIGVEPMLGAVFDLAEAGPGDAAVVSESGEIRWEMAVTATRRDDTHDTHAAHDAHDAHDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q509</accession>
    <name>C7Q509_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5097</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5097"/>
    <dbReference type="EnsemblBacteria" id="ACU73957">
        <property type="protein sequence ID" value="ACU73957"/>
        <property type="gene ID" value="Caci_5097"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5097"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="IVNTTMG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="93"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32378" checksum="E214B5B54712C0A6" modified="2009-10-13" version="1">MTAATTGTASRAAAGSGGTRPGGPHRTNWIPTIILLVGAVYCVLPVVWIVIASTKTNSELFSSAPFAPSFHGGFFSNLRALFAYDHGIFTRWAVNSVIYAVGGATLSTIVCGCAGYALGKYRFYGSVWLFRVIVAAVLLPQIMLAIPQFLLLAKLGMTNNYAAVILPQLVSPFAIYLCKVYAESSVSDQVLEAARVDGASEWRSFLSIGARLMTPALVTVFLLQFIGIWNNFLLPFVMLNRDNLFPLTEGLYGLLIITGGQAAQYTIVIVGVLVSIVPLAAVFLLLQRYWRVDLVSGGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q522</accession>
    <name>C7Q522_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793699.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5111"/>
    <dbReference type="EnsemblBacteria" id="ACU73970">
        <property type="protein sequence ID" value="ACU73970"/>
        <property type="gene ID" value="Caci_5111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5111"/>
    <dbReference type="eggNOG" id="ENOG502Z97F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049601_0_0_11"/>
    <dbReference type="OMA" id="SIRPWFV"/>
    <dbReference type="OrthoDB" id="587274at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08589">
        <property type="entry name" value="PI-PLCc_SaPLC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032075">
        <property type="entry name" value="PI-PLC-C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16670">
        <property type="entry name" value="PI-PLC-C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980603" evidence="1">
        <location>
            <begin position="31"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="36952" checksum="E1EE86E3E1BE6591" modified="2009-10-13" version="1" precursor="true">MSAPWLRRLTAGAATLGAAVLALAATIAPAAADTSSAPLSHSSVVGLHNTYDDGSQFPHLANALDTGTSMIELDTWTDVFTTEWKVSHSNPLGNSNNCVNASKPADIYTGSANKDLRSCLDDVKYWLASHSTTGPLYIKLELKQGFEANSGLGPAQLDALINAHLGSLVYRPSDLLNGTYPTLDAAAKADAWPARSALAGKVILYVIPGTVELGNPFDTLHTDVEYATYLKNLAAAGKASQAAVFPSVLGAQTGDPRSQYSDTSIRPWFVVFDGDANTYVTSVDTSWYDTNHYLLTMTDAQNVAPALSDTAPSQSDAQARVALLASKHATVVSTDWTGLPPVLSEVLPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q533</accession>
    <name>C7Q533_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793710.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5122"/>
    <dbReference type="EnsemblBacteria" id="ACU73981">
        <property type="protein sequence ID" value="ACU73981"/>
        <property type="gene ID" value="Caci_5122"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5122"/>
    <dbReference type="HOGENOM" id="CLU_1060468_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="28385" checksum="76546B8100DF3302" modified="2009-10-13" version="1">MGLDAFFDGLEKLVDRLRERWPRAMFWTVVALWSVAAAIPTAGAALTGAGWFSALIPLAPLVVIGLTYWGGVEWIPTSVWVAALAVWALLPGALASAGPRSGAAKDGTAAFLFCYGQLLVALLTAICVRRGFSLRTPFAQLRLMRLRLVAAAFPLAVSFRLGTSGPSRGRGWDVLAWLLVFTTVMAACAFPSSRTALIAALAIAAGAWAILAHADPHDRWAQVGENGWIWAAGCYQWLRASRQDFWHGGHERVNWQRATSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5E6</accession>
    <name>C7Q5E6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7085"/>
    <dbReference type="EnsemblBacteria" id="ACU75915">
        <property type="protein sequence ID" value="ACU75915"/>
        <property type="gene ID" value="Caci_7085"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7085"/>
    <dbReference type="HOGENOM" id="CLU_2153810_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981427" evidence="1">
        <location>
            <begin position="28"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="10677" checksum="E643AE796832160B" modified="2009-10-13" version="1" precursor="true">MSFVTKTLATTATVAALILAGAGAASADVGASGSNLGVTGGSTSGNSGVGTGNVVQGTSGNVTQGAGNVVGDHDVVGNGDAVVINVVGWQGGWDGGWHGAWHHRCYHGFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T0</accession>
    <name>C7Q5T0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase, DhaK subunit</fullName>
            <ecNumber evidence="2">2.7.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.29" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785321.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1101"/>
    <dbReference type="EnsemblBacteria" id="ACU70027">
        <property type="protein sequence ID" value="ACU70027"/>
        <property type="gene ID" value="Caci_1101"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1101"/>
    <dbReference type="eggNOG" id="COG2376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_0_0_11"/>
    <dbReference type="OMA" id="MLSAACP"/>
    <dbReference type="OrthoDB" id="857242at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012736">
        <property type="entry name" value="DhaK_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02363">
        <property type="entry name" value="dhaK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="1">
        <location>
            <begin position="7"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="33869" checksum="05CB1AB851BE6CF1" modified="2009-10-13" version="1">MKKLINSPDSVLGDALAGVAAAHPALHVDTEARVITRAGGPSVGRVALISGGGSGHEPLHGGFVGPGMLHAACPGEVFTSPVPDQMLAAAQAVNGGAGVVFIVKNYTGDVMNFEMAAELAGDDGIEVATILVDDDVAVKDSTWTAGRRGTGATVFVEKIAGALAEQGADLAEVAEIGRRVNAASRSFAVALTACTTPAAGKPGFDLAEDEMEVGVGIHGEPGRSREKLEPASAIVARSLDAIFADQPLAAGDQTIVMVNGLGGTPLIELYVAYAEVAAYFAERGVQIARNLVGNYITSLEMAGVSLTVCKADAQMLALWDAPVNTPALRWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q659</accession>
    <name>C7Q659_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787358.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3156"/>
    <dbReference type="EnsemblBacteria" id="ACU72065">
        <property type="protein sequence ID" value="ACU72065"/>
        <property type="gene ID" value="Caci_3156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3156"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="NLFTEPY"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="32524" checksum="ECFC69CA0CE4FAC5" modified="2009-10-13" version="1" precursor="true">MSRAKRGGRRSKTLVGLWLVAPYAAYLIVVYAVPIIQGVRISVLDYVYAAPGASVPQPFVGLKNYRAAWSNPQLRRSFLNIGEFLVINVPLTVILGMTLAAVLAKLTRMKAFFRSAFFVPYVTASIAVIGVWYFLFSQSGLINHVLGGLAPNPSWLVNSKLAMVVIALEVTWKQLGFYVLLYLAGVLLIPDSLYEAASIDGAGVVRQFRSITVPALRNITILVTTLALIVGANLFTEPYLLTGGGGPNGATMSPALLIYQDGVEQGKPGVGAAIGIMLTLFVLLVAGLGAGARRLAQSREGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q733</accession>
    <name>C7Q733_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7217"/>
    <dbReference type="EnsemblBacteria" id="ACU76046">
        <property type="protein sequence ID" value="ACU76046"/>
        <property type="gene ID" value="Caci_7217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7217"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_296100_0_0_11"/>
    <dbReference type="OMA" id="CLANMGR"/>
    <dbReference type="OrthoDB" id="809847at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="994" mass="107099" checksum="14B98C14B40488E8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q758</accession>
    <name>C7Q758_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1221</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1221"/>
    <dbReference type="EnsemblBacteria" id="ACU70146">
        <property type="protein sequence ID" value="ACU70146"/>
        <property type="gene ID" value="Caci_1221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1221"/>
    <dbReference type="eggNOG" id="COG2096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083486_0_0_11"/>
    <dbReference type="OMA" id="HQACTVV"/>
    <dbReference type="OrthoDB" id="1401910at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="7"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="21642" checksum="BE5FE82A87D986F9" modified="2009-10-13" version="1">MVNLTRIYTRTGDDGTTALGDLSRVRKTDARLAAYADVDEANAAIGLAVAFATNDLGMLHDGIRALLLRVQNELFDLGADLSTPPAENPEFPPLRIEPEYVERLEAACDEWNETLAKLRSFILNGGTVVAAQLHVARTVVRRAERSAWAAVEEYGDGVNPLAVKYLNRLSDLLFILARVANTDSHGGDGDVLWVPGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7R3</accession>
    <name>C7Q7R3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3349"/>
    <dbReference type="EnsemblBacteria" id="ACU72256">
        <property type="protein sequence ID" value="ACU72256"/>
        <property type="gene ID" value="Caci_3349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3349"/>
    <dbReference type="eggNOG" id="ENOG502ZNUP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1218032_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="22870" checksum="699F8E307ADEAD5F" modified="2009-10-13" version="1">MARLPHPPPTPALTRAVREWSGWLAVAAGAVLCVLGWYGISGENTIEQQLPYLASATIPGAALIVAGAALIASRPEPTNARIETLYTLLVADADTPAAPPPPPENSHELLAVPGGTLYHRRDCPLIAGKPTAEVIDEATVFERSLTPCPVCEPPTLPPAGPGPTGSAPTQPADPAASGPTEPGIDPRGTTPDQPAADPAASDPTSSGGGAPPAGTDPDQHPTTPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U6</accession>
    <name>C7Q7U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793842.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5254"/>
    <dbReference type="EnsemblBacteria" id="ACU74113">
        <property type="protein sequence ID" value="ACU74113"/>
        <property type="gene ID" value="Caci_5254"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5254"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699598_0_0_11"/>
    <dbReference type="OrthoDB" id="999660at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="394" mass="43963" checksum="3F9FB20E9F169C42" modified="2009-10-13" version="1">MALGDRGYADDDDRRRRRVLTRRPPAPLPPRRPPAPPRRISLIWRLRPPLALRGRRAPDPRWIIGLFVGLAAILTLSWIGRTVAPYWPNFALNTAADLIGAVFTIYVITPIIERAGQGGVREHAELDYSQFLGSADRATSVIRILDTYSNLLAEPYAQRFETMVREAVARGVSIRVLLINPTTLAAEQRDLELGRADELGPMLERNLETVARLHRAFEQEGGPRGLGAAADFQVRLYSSGPDITMYRWDDRALVSFYPVGKLSGRAEQLEVTVDSALGSFVNNRFQAVWHAAAPHQALTPITVADGNIERTYLVRFVDLDGRRFVASRRVERFMRRAVGEISAVNGGRDYRLEPADRSQVGALLDAAFRRVYGEIPDTAYLLLRTSDPSVTAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z8</accession>
    <name>C7Q7Z8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793894.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5306"/>
    <dbReference type="EnsemblBacteria" id="ACU74165">
        <property type="protein sequence ID" value="ACU74165"/>
        <property type="gene ID" value="Caci_5306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5306"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066193_3_1_11"/>
    <dbReference type="OMA" id="VEWIWSA"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="141"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="26232" checksum="8ED5491FD34D46D1" modified="2009-10-13" version="1">MSSVYAERRSRRVPGRFVVCAWTRVNLGDGEHRQLVVPDGCSDLTWQGGVVRLVGPDRGAWRAGLAAGAAVAGVRLRAGAARLLLGRMPVDEVRDAQVPLESLTGGVGELTERLAATDSPWAAARVLEDFVAALTPRYEPDGAVEQVVRMLRPGETPQVPALADAVGLSERQLRRRFTEAVGYGPKTLHGILRFQHALDLGRRAEPYGLAAIAHEAGYADQAHFTREVRRLAGMTPTELLGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D2</accession>
    <name>C7Q8D2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7291"/>
    <dbReference type="EnsemblBacteria" id="ACU76120">
        <property type="protein sequence ID" value="ACU76120"/>
        <property type="gene ID" value="Caci_7291"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7291"/>
    <dbReference type="eggNOG" id="COG2337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121823_1_1_11"/>
    <dbReference type="OMA" id="NDIGNQY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="13299" checksum="C0556280BA14F0E4" modified="2009-10-13" version="1">MSGAVPALRRGDMCWVNLDPARGGEIKKRRPAVVVSNDGVNSAVHRYGRGVVTVVPVTSNTERVYPFQILIDAADHPGLRTDSKAQAEQVRTVDVARIGSRITTLSPSTMRSLDAALRLHLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8I6</accession>
    <name>C7Q8I6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795902.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7347"/>
    <dbReference type="EnsemblBacteria" id="ACU76174">
        <property type="protein sequence ID" value="ACU76174"/>
        <property type="gene ID" value="Caci_7347"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7347"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115786_0_0_11"/>
    <dbReference type="OMA" id="DHYDDDW"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019967">
        <property type="entry name" value="F420-dep_enz_PPOX_Rv0121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03668">
        <property type="entry name" value="Rv0121_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15204" checksum="D2789C24B5174D52" modified="2009-10-13" version="1">MTPEQARATFLSQPHAVLATADASGVPHLVPVVFAAIGDSLALVVDHKPKRSTDLKRLRNIAANPYVSLLAEHYDADWNALWWARADGTARVSPLTPEVLAAFRRKYPQHDAAPPAGPQVVVTVAKWSGWTAAARPAGGTGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R4</accession>
    <name>C7Q8R4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785623.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1406"/>
    <dbReference type="EnsemblBacteria" id="ACU70329">
        <property type="protein sequence ID" value="ACU70329"/>
        <property type="gene ID" value="Caci_1406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1406"/>
    <dbReference type="eggNOG" id="ENOG5033MS8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_207336_0_0_11"/>
    <dbReference type="OMA" id="CANCAAP"/>
    <dbReference type="OrthoDB" id="2085359at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="6461" checksum="EF596AB3D3B87017" modified="2009-10-13" version="1">MCCEHLICANCAGPVSEGRCSVCRGQRAQMHHETGGLSFSAMVAVLLTLLIAVAFLTTTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q944</accession>
    <name>C7Q944_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787657.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3458"/>
    <dbReference type="EnsemblBacteria" id="ACU72364">
        <property type="protein sequence ID" value="ACU72364"/>
        <property type="gene ID" value="Caci_3458"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3458"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_9_11"/>
    <dbReference type="OMA" id="CIHAQFR"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05931">
        <property type="entry name" value="FAAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040097">
        <property type="entry name" value="FAAL/FAAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="582"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1701"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1173"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1625"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1629"/>
            <end position="1645"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="619"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2250" mass="239381" checksum="DE351EEA2B92F245" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q958</accession>
    <name>C7Q958_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3472"/>
    <dbReference type="EnsemblBacteria" id="ACU72378">
        <property type="protein sequence ID" value="ACU72378"/>
        <property type="gene ID" value="Caci_3472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3472"/>
    <dbReference type="eggNOG" id="COG2091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_5_11"/>
    <dbReference type="OMA" id="HDITLWS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="16"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="585"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1480" mass="157845" checksum="CD1832744BF7075E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C0</accession>
    <name>C7Q9C0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proline-specific peptidase</fullName>
            <ecNumber evidence="5">3.4.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5407"/>
    <dbReference type="ESTHER" id="catad-c7q9c0">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74266">
        <property type="protein sequence ID" value="ACU74266"/>
        <property type="gene ID" value="Caci_5407"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5407"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_15_1_11"/>
    <dbReference type="OMA" id="TWYRVTG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005945">
        <property type="entry name" value="Pro_imino_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005539">
        <property type="entry name" value="Pept_S33_TRI_F1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="37"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="31037" checksum="0450494E964CE8DE" modified="2009-10-13" version="1">MVGISENSISGTGTVPFRDGHTWYRVFGELSAAGPSPLLLLHGGPGAVHDALLPLADLFSHERPVVLYDQVGCGNSTRRPEWPAQAWTLELHLEELDALVAHLGLTRFHLLGHSWGGFLASEYALVHPEHVASLTLFSTAASSELMMASIIGRYTAIAEQGRSPAEFVTRHICRVPMPEPLAYTFAQLAEHPEVNAAMIGSDEATGELTGTLRDWSVIGRLPAIGAPTLVLGGEFDELDAAARQPFLDGIPDVRGHEFTDASHVAYIERPEAVRVVLGVFLTEHDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9P0</accession>
    <name>C7Q9P0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalamin (Vitamin B12) biosynthesis CbiX protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7383"/>
    <dbReference type="EnsemblBacteria" id="ACU76209">
        <property type="protein sequence ID" value="ACU76209"/>
        <property type="gene ID" value="Caci_7383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7383"/>
    <dbReference type="eggNOG" id="COG2138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056929_3_0_11"/>
    <dbReference type="OMA" id="PCRVSYA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26707" checksum="84C0D6619BF593A3" modified="2009-10-13" version="1">MTKGQAMLAVAHGSRDPRHREVITGLVDAVRDQRPELRVETAFLDHCGPTPARALHGLVRDGYQDVKVVPLLLNTAFHVRQDIPVAVAAAHEALPRRWRAGVAQPVLAAPLGPHPLLTAGLERRLREAGVWPGDEEASVVLAWAGSSDRVAAAAVDELAEGWERSGWERVVAVPAVGDLAGEAVRELRGRGARRVVVAPYFLAPGFLADRIRCSAQAAGADVVAAELGNAPEVASAVLARFDGAVSACLAHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAI7</accession>
    <name>C7QAI7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Galactosylceramidase</fullName>
            <ecNumber evidence="2">3.2.1.46</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Galactosylceramidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3581</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 59 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.46" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792215.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3581"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH59">
        <property type="family name" value="Glycoside Hydrolase Family 59"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72486">
        <property type="protein sequence ID" value="ACU72486"/>
        <property type="gene ID" value="Caci_3581"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3581"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015456_1_0_11"/>
    <dbReference type="OMA" id="NCNAGYE"/>
    <dbReference type="OrthoDB" id="228499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004336">
        <property type="term" value="F:galactosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006683">
        <property type="term" value="P:galactosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001286">
        <property type="entry name" value="Glyco_hydro_59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15172">
        <property type="entry name" value="PTHR15172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02057">
        <property type="entry name" value="Glyco_hydro_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983071" description="Galactosylceramidase" evidence="6">
        <location>
            <begin position="38"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="668"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="801" mass="83402" checksum="CAD9461384567603" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAR4</accession>
    <name>C7QAR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5528"/>
    <dbReference type="EnsemblBacteria" id="ACU74387">
        <property type="protein sequence ID" value="ACU74387"/>
        <property type="gene ID" value="Caci_5528"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5528"/>
    <dbReference type="eggNOG" id="COG3468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179377_1_0_11"/>
    <dbReference type="OMA" id="KHTHDEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045684">
        <property type="entry name" value="DUF6191"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19690">
        <property type="entry name" value="DUF6191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="10460" checksum="CB53C72BD375ACA4" modified="2009-10-13" version="1">MSVFFDMFAPSRRHLEEERNRLEWTRDEEGEGDPHRGPIDLDSGVVSIKTAGPDPDPNLEPDPEPTETPQVSETPQAGAAPQVTKPAASGTPRSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAU0</accession>
    <name>C7QAU0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5554</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5554"/>
    <dbReference type="EnsemblBacteria" id="ACU74413">
        <property type="protein sequence ID" value="ACU74413"/>
        <property type="gene ID" value="Caci_5554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5554"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037625_0_0_11"/>
    <dbReference type="OMA" id="YGWPQFT"/>
    <dbReference type="OrthoDB" id="854536at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="73"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="59973" checksum="A59E55FAE62302F7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW5</accession>
    <name>C7QAW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5579"/>
    <dbReference type="EnsemblBacteria" id="ACU74438">
        <property type="protein sequence ID" value="ACU74438"/>
        <property type="gene ID" value="Caci_5579"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5579"/>
    <dbReference type="HOGENOM" id="CLU_2521524_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="84" mass="9685" checksum="1051B575147FED22" modified="2009-10-13" version="1">MQSLEKSLEDTGLEAVISRLRNHDPEVLADLAQRQLRHRRRRRRGRRERIGLPRAGEMGVSAKYGYWDVGAFSRARPTGFGLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ1</accession>
    <name>C7QAZ1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5605"/>
    <dbReference type="EnsemblBacteria" id="ACU74464">
        <property type="protein sequence ID" value="ACU74464"/>
        <property type="gene ID" value="Caci_5605"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5605"/>
    <dbReference type="eggNOG" id="COG1314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094156_7_1_11"/>
    <dbReference type="OMA" id="WFACIVV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="8530" checksum="566920F6E9FDFC24" modified="2009-10-13" version="1" precursor="true">MTLYQWIVSGILVATSLLLIMSVLLHKGKGGGLSDMFGGGVSGGLQGSSVVERNLDRISVVLSSVWISCIVALALLYKHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB34</accession>
    <name>C7QB34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796050.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7500"/>
    <dbReference type="EnsemblBacteria" id="ACU76325">
        <property type="protein sequence ID" value="ACU76325"/>
        <property type="gene ID" value="Caci_7500"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7500"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_2_11"/>
    <dbReference type="OMA" id="CETDARH"/>
    <dbReference type="OrthoDB" id="1992113at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18719" checksum="A984DC9330AB0101" modified="2009-10-13" version="1">MYRANIDAVTAYFARRTTDPQTVADLTADTFLEAITSYSTFDPRRGTARAWLFGIARRTFAQHCETDARHRERAVRLAGRRDLAADHVEELLDRIDAEREGRALVSALTKLPDLDRQAVELVDIAGLKAKEAAAVLGISAGALRMRLMRARTRLRRAHTSRPDSGVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBN1</accession>
    <name>C7QBN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein tyrosine/serine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785902.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1687"/>
    <dbReference type="EnsemblBacteria" id="ACU70608">
        <property type="protein sequence ID" value="ACU70608"/>
        <property type="gene ID" value="Caci_1687"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1687"/>
    <dbReference type="eggNOG" id="COG2365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_3_2_11"/>
    <dbReference type="OMA" id="WDGCLNV"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="114"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="24811" checksum="8FC08A8B82518EB6" modified="2009-10-13" version="1">MIATRNLAWDGCVNVRDLGGLGRIKPGAVVRMEAPTSLTAAGWTAAWDHGVRTVLDLRAEDESEADQTPRPDGIAAVRVPLDPEPGTAFHDHWTPIDNMATPLYLPALLAEYPDRVVAAVRAIATAAPGCVVFHCSGGKDRSGLIALVLLAFAGAEPEEIVADYLLTFDRMKARYDALGIRDQRVAVGERLAQHGTTIEASLSTTIAGLTMPGYLLDNGLSAADLSALESRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBR2</accession>
    <name>C7QBR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785933.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1718"/>
    <dbReference type="EnsemblBacteria" id="ACU70639">
        <property type="protein sequence ID" value="ACU70639"/>
        <property type="gene ID" value="Caci_1718"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1718"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032306_1_0_11"/>
    <dbReference type="OMA" id="WIDFRRP"/>
    <dbReference type="OrthoDB" id="1309717at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="44553" checksum="B9F06DA5F9AF6ADC" modified="2009-10-13" version="1">MRLDGVWWLEDRLRQQLRPVPFEVPAGVSLIEVRLDYDRSAGAVLDLGCAGPEGFRGWSGGARQEFAVGAQRSTPGYLPGEILPGVWHVWLGLHRVPPEGVRYSLEITFSDKRAARTLEYRSHSVRALQRPPARELPGVEGMRWYAGDLHAHTDHSDGTLSVGALAELAAETGLDFLAVTDHNTISHYPLLEKHSATSGVTLIPGQEVTTDLGHANVWGAKEWIDFRRPASQWMKQAEKAGALFSVNHPLAGDCAWRHQLTTQPSIAEIWHWSWFDRTWGWPLAWMKRHPAAIIPVGGSDFHEPGGTPASLGAPITWVLAEECMTSAILAGIAAGRTAVSADRTGPLVLRCGDEIAAVDADGLILVRPDETRVVVRADGAGRQSFPATQSGMYRLETWRNEVVALCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC08</accession>
    <name>C7QC08_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792356.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3725"/>
    <dbReference type="EnsemblBacteria" id="ACU72627">
        <property type="protein sequence ID" value="ACU72627"/>
        <property type="gene ID" value="Caci_3725"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3725"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004495_0_4_11"/>
    <dbReference type="OMA" id="MAAYVMV"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="549" mass="57329" checksum="91ACF8A72EE44C18" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF8</accession>
    <name>C7QCF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5748"/>
    <dbReference type="EnsemblBacteria" id="ACU74606">
        <property type="protein sequence ID" value="ACU74606"/>
        <property type="gene ID" value="Caci_5748"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5748"/>
    <dbReference type="HOGENOM" id="CLU_849134_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="33895" checksum="25A7F3C65F18B417" modified="2009-10-13" version="1">MSSGVSVLVVVHPPKVIGDPLVFEQFLHDLTVTAYQVDFAHPDTLAAAPHTVIGSARYTAENDSTNTIYQLTNVLETKLYSAAVAVIDVDPAVLAKYSSPQSLVNVVVSVTRGGSKIREDSLDYDVQLWGSSGSPYAVPLTSVLGVGGTSLALDGTESGGIVGFYLALPDPAFDAGSGTTYLVPPADGGAPAFADLKAAVDAILAEDPSGVSDPADLTPQQCLHIARELVGNRYAAPLPAPSSAVQELYTSGSDDDRKHFESTLQSYYATLDAEAGRLAGFIYAWSAALNCTGLTKAAARAALTFPLRVTSTPGVAQAAQAGVVLHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCQ4</accession>
    <name>C7QCQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoprotein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7693</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796242.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7693"/>
    <dbReference type="EnsemblBacteria" id="ACU76517">
        <property type="protein sequence ID" value="ACU76517"/>
        <property type="gene ID" value="Caci_7693"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7693"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_264588_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="608"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1022"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1223"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1246"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1263" mass="132744" checksum="B152C29FBE0B66EB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY3</accession>
    <name>C7QCY3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1772</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785987.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1772"/>
    <dbReference type="EnsemblBacteria" id="ACU70693">
        <property type="protein sequence ID" value="ACU70693"/>
        <property type="gene ID" value="Caci_1772"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1772"/>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_6_1_11"/>
    <dbReference type="OMA" id="ATGGVRC"/>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="7">
        <location>
            <begin position="21"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="820" mass="88625" checksum="1C051AEC7F6A4182" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD21</accession>
    <name>C7QD21_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-lysine N6-monooxygenase MbtG</fullName>
            <ecNumber evidence="5">1.14.13.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lysine 6-N-hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Lysine N6-hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Lysine-N-oxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Mycobactin synthase protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_1810</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine + NADPH + O2 = H2O + N(6)-hydroxy-L-lysine + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:23228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57820"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.59" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786025.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1810"/>
    <dbReference type="EnsemblBacteria" id="ACU70731">
        <property type="protein sequence ID" value="ACU70731"/>
        <property type="gene ID" value="Caci_1810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1810"/>
    <dbReference type="eggNOG" id="COG3486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020931_0_0_11"/>
    <dbReference type="OMA" id="YTRYFHA"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047091">
        <property type="term" value="F:L-lysine 6-monooxygenase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="PTHR42802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="K_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU70731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="48505" checksum="53C4E2D89534C330" modified="2009-10-13" version="1">MQHYDVVGVGIGPFNLSLAALAEPLRENHSLQPLFLERQPVFAWHRGMMLDGATLQVPFLADLVSLTDPTSRFSVLNWLRETDRLYSFYFAENLFLQRREYEAYCQWVAAQLPFCRFGTAVTKIRRSEAGFEIEYTAPSGPVLVSAANIVLGIGTEPVMPFEVPGAPPHAALHSADYMVHRERLRTLDDVTVIGSGQSGAEIVLDLLRSGAPGQRVRWLTRSAAFEPMEYSKLGLEHFTPDYTRFFHGLREDVRADLLRGQGRLHKAISFETIAELHAELHMRSFDSLYGGTLGLAGDTGATLLPGVSVTGGAWRPGGPGAVELTCLHERQKREFGVLTDAVVLATGYRERVPGFLDADLEQLLGAADLDHRIAPGVYAQNAERHTHGVGAPDLGLGAHRAAVILNALTGRTVYDLPRRAAHTAFDPEAAAERDPGIRIEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDX9</accession>
    <name>C7QDX9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7743"/>
    <dbReference type="EnsemblBacteria" id="ACU76567">
        <property type="protein sequence ID" value="ACU76567"/>
        <property type="gene ID" value="Caci_7743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7743"/>
    <dbReference type="eggNOG" id="COG2740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147970_0_2_11"/>
    <dbReference type="OMA" id="TCVGCRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8401" checksum="1722D7F776826D79" modified="2009-10-13" version="1">MRTCVGCRAKAAKTELLRVVAVEGAVVPDLRGRSPGRGAHLHVDPGCLALAEKRRAFPRALRVDGPLETTAVRALLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDZ3</accession>
    <name>C7QDZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methylated-DNA/protein-cysteinemethyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7757"/>
    <dbReference type="EnsemblBacteria" id="ACU76581">
        <property type="protein sequence ID" value="ACU76581"/>
        <property type="gene ID" value="Caci_7757"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7757"/>
    <dbReference type="eggNOG" id="COG0350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_2_11"/>
    <dbReference type="OMA" id="SACAMNA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="6">
        <location>
            <begin position="82"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="166" mass="17097" checksum="2144F4EFA3921394" modified="2009-10-13" version="1" precursor="true">MSTLSYTTIPTPAGPFTVLADADDTVHAAGFTDDPAFLAGMLSAPVPEEGAHEPVAERVAAYFGGDLAALDDVAIAYRATGPFRTAAWDAMRAVKAGDTISYTELAATAGNPAAVRAAGSACASNAIALFVPCHRIVRSDGSSKNFLYGLECKATLLAHERQHAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA6</accession>
    <name>C7QEA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydantoinase B/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ACU70797">
        <property type="protein sequence ID" value="ACU70797"/>
        <property type="gene ID" value="Caci_1877"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1877"/>
    <dbReference type="eggNOG" id="COG0146">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_B" evidence="1">
        <location>
            <begin position="3"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="613" mass="66801" checksum="71A88904E189AB42" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEJ5</accession>
    <name>C7QEJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1966"/>
    <dbReference type="EnsemblBacteria" id="ACU70886">
        <property type="protein sequence ID" value="ACU70886"/>
        <property type="gene ID" value="Caci_1966"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1966"/>
    <dbReference type="eggNOG" id="ENOG502ZBUI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="DNDYFYE"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33052" checksum="D69C1A0F0E756F15" modified="2009-10-13" version="1">MALAGIATVLITRGYLAATGYPRIGGGEIHIGHVVWGGLLMIAALTVALVWAGGRARVWTALVGGVGIGLFVDEVGKYLTTTNDYFFRPAAAIIYLVFAALLVVASLLGRDTVAEAGEDSERLAAAAQIAASGLISGLTPQEREAATRMLAGCPDQDRDAVLRLLAVAPLRAPSRVAVLLNRIRGWADRVSALRGADAVFFVLLILSHIVVAIVFIAQAATGEPHSTDAGAITISAVTRSAAAILVVGATVMRLRGRQLTSYRLAKAAILMDLLITEAFNFHDSQFSAVAELPHLLVAFAFFSIRQRQVEAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEU5</accession>
    <name>C7QEU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3989"/>
    <dbReference type="EnsemblBacteria" id="ACU72865">
        <property type="protein sequence ID" value="ACU72865"/>
        <property type="gene ID" value="Caci_3989"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3989"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3388686_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="32" mass="3197" checksum="0C8C62926CDB1A8D" modified="2009-10-13" version="1">MEQSLDNPAVGVTAARQSVPFAVDAQPGGGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEY4</accession>
    <name>C7QEY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794471.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5884"/>
    <dbReference type="EnsemblBacteria" id="ACU74742">
        <property type="protein sequence ID" value="ACU74742"/>
        <property type="gene ID" value="Caci_5884"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5884"/>
    <dbReference type="eggNOG" id="COG0557">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038135_1_0_11"/>
    <dbReference type="OMA" id="WNAQISL"/>
    <dbReference type="OrthoDB" id="1602988at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040596">
        <property type="entry name" value="RNase_II_C_S1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18614">
        <property type="entry name" value="RNase_II_C_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="53"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="532" mass="57938" checksum="481FAD0BBB1236E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF03</accession>
    <name>C7QF03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5903"/>
    <dbReference type="EnsemblBacteria" id="ACU74761">
        <property type="protein sequence ID" value="ACU74761"/>
        <property type="gene ID" value="Caci_5903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5903"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OMA" id="ESRAMNH"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="49000" checksum="C060B7DD459C7BC7" modified="2009-10-13" version="1" precursor="true">MSDQARRSRGVLPALVLSVLAFSLVQTSVVPILPTLQKNLHVAGSGITWLMTANLLSAAVLTPLLARIGDLRGRKPVLVVAIAGVLVGGVLGGIGGSFGLLLIARVVAGTGGAILPLAVAVVRDELPRKKVTGGVAMVSAALGVGSGLGLVATGVVMEHFSYESVFWMGAVLAAVALALVVWLVPHDPIKAEGKADPLGALLLAGWLSALLIAVSQGNDWGWGSARTLGLFVTAVVVLVLWVVVERRVASPLVDIAMLAKPAVAVTNTAGVLVGFAMYGSFLLMSDFTQTPKAVGYGFGASVLASGWMLFPSAVGSFAAAPVGAALIKRGGPRLPLVLGGAFAAAGLGLLVFAHSSSWHVVVASGVMGVGVGMAYAAMPAYINASVPVQQSGIANGMNAVLRTVGGAVGTAVIGAVLTGNMKQVAPGVQLPTIDAYSHAFLIASALALVAAVVPFLVKAPQMTAMTTPDTIDAGVDSEPKAMAAANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF72</accession>
    <name>C7QF72_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794559.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5972"/>
    <dbReference type="EnsemblBacteria" id="ACU74830">
        <property type="protein sequence ID" value="ACU74830"/>
        <property type="gene ID" value="Caci_5972"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5972"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="FGIDRQD"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="230"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="36836" checksum="A1DC5F7526D06D15" modified="2009-10-13" version="1">MTLTAPRPRLAPTRDRGTVAVLLFRDAPLFESSIPISVFGVDRRVMGLPYYRLLVCAGEAGPLATTGSLRVSTPFGLSGADQAGTVIVPAWRAPGERPPEPALAAVRKAHKEGARLAAFDSGVFVLAAAGVLDGRGATTHWMYAPALARHHRRVKVDARSMQIDHGDVVTGAGAAAGLDLCLYLVRTDHGAEAASALARRLVVGPGRRSGQAAYFDRHLPSELGAGTPIGDAMSWALDHLAEPFDVDEFAKHSAMSRRTFDRRFLEVTGTTPLRWVNSQRVIAAQRILESTDLPVDEVARRSGFASGPAMRANFLRVLGTQPARYREAYLASRARGGREGREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFX5</accession>
    <name>C7QFX5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="2">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2032</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2032"/>
    <dbReference type="EnsemblBacteria" id="ACU70952">
        <property type="protein sequence ID" value="ACU70952"/>
        <property type="gene ID" value="Caci_2032"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2032"/>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_11"/>
    <dbReference type="OMA" id="MYDGASA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="48435" checksum="1A0F0C007E9EB585" modified="2009-10-13" version="1">MGHPYIPNSDPEIRGRMLAAIGAASVEEFYADIPDAIRLHRPLDLPAPLRSEAELVRHMDRLLSRNKPAELSFLGAGCYRHHVPAVVEEIANRSEFLTAYAGEPYEDHGRFQALWEYQSLMGELLELDVVNVPTYDGFQAAGTALRMAGRVTGRRRLLLVGPVDPDKMSKIEDFVRPDHDVEVLDGTDDGWQAADLVVGADVAAVYIEAPNYHGVLDPALPLLAERAHAVGALLVVGCNPISLGVVASPASYGADIVCGDIQPLGIRMSFGGGNAGFIATRDEQRLVREFPSRLFGVVPTVVEGEYGFGDVFYDRTSFALREEGKEWVGTAAALNGIMAGVYLALMGPHGMREIGETILALTAYAQERLAAVPCVSAPNGEAGAGLVSFADFVVRFTGLLTAADINALLLERGIQGGKVLSETDALFCVTEVHTREDVDRLAAVLEEIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGB1</accession>
    <name>C7QGB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792685.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4091"/>
    <dbReference type="EnsemblBacteria" id="ACU72956">
        <property type="protein sequence ID" value="ACU72956"/>
        <property type="gene ID" value="Caci_4091"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4091"/>
    <dbReference type="HOGENOM" id="CLU_2697838_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="7640" checksum="B3DE3F7D58DFE40B" modified="2009-10-13" version="1">MAAGEAEDSRSAADEVEVARVKGSAPDSWRPAVRPAAAIAASRKKIQSIAEWPSATLLNSSPEWSKMTPAGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR9</accession>
    <name>C7QGR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794678.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6094"/>
    <dbReference type="EnsemblBacteria" id="ACU74949">
        <property type="protein sequence ID" value="ACU74949"/>
        <property type="gene ID" value="Caci_6094"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6094"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="LDEHVYA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="162"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="24933" checksum="5F528FCB0961961C" modified="2009-10-13" version="1">MIQVLIADDQALVRTGFRMILENAPDMEVVAEAADGAEAATLALDLRPDIVLMDVRMPETDGVQATRRICAERPGHTRILMLTTFDLDEYVYASLRAGASGFLLKDTLAADLLSAIRTVAAGDAVVAPSVTRRLLERFVGTNTAGASPTGTTGTTGTASLASALAADTLTDREREVLAHLARGLSNSEIAAHIYIGEGTVKTHVSRILAKLDLRDRVQAVVYAYESGLVRAGTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGW7</accession>
    <name>C7QGW7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalamin B12-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796542.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7994"/>
    <dbReference type="EnsemblBacteria" id="ACU76817">
        <property type="protein sequence ID" value="ACU76817"/>
        <property type="gene ID" value="Caci_7994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7994"/>
    <dbReference type="eggNOG" id="COG2185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128233_0_0_11"/>
    <dbReference type="OMA" id="VYTGLHQ"/>
    <dbReference type="OrthoDB" id="1335734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="135" mass="14154" checksum="0D07C782ED65F082" modified="2009-10-13" version="1">MSQSAPVRVVIAKPGLDGHDRGAKVVARALRDAGVEVIYTGLHQMPDQIVATAIQEDADAIGLSILSGAHMTQCAKVIEVLKEKDASDIKVFVGGIIPEADFPALKEMGVVAIFTPGTSTQQIVDWVNGNLAHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR5</accession>
    <name>C7QHR5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2171"/>
    <dbReference type="EnsemblBacteria" id="ACU71090">
        <property type="protein sequence ID" value="ACU71090"/>
        <property type="gene ID" value="Caci_2171"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2171"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="VARWALI"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="85"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="34342" checksum="8CE2BD5B2729A89F" modified="2009-10-13" version="1" precursor="true">MTTHTERGRLGRSRPARSRSVFSGLAPLAWIGPAIALIAFAVLWPVVKMVQSSTTHWSRYGVNLGSNGTDNYNKLFKEQDLSGVLERTGIWVVVVVTLTMVISLGVAQLFNQKFPGRTVARWALIAPWAASVMMTSIIFKWMLYPGYGFINIILNDLGLVDRNSPTADWLGHSGSGFIWEMAVAIFVSIPFTSYTVIAGLQTVPAEVYEAARVDGASKVRTYFSITLPLLRPALLVATVINVMNVFNSFPIIWEMTHGGPGYDTSTTTVFMWILKRQNIGESAALSVVNFALVIVIVFAFLKVSKWNSEGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR8</accession>
    <name>C7QHR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786386.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2174"/>
    <dbReference type="EnsemblBacteria" id="ACU71093">
        <property type="protein sequence ID" value="ACU71093"/>
        <property type="gene ID" value="Caci_2174"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2174"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="MEYNLAD"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="445"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="58387" checksum="5D6C19BE4D2F574A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI56</accession>
    <name>C7QI56_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792830.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4237"/>
    <dbReference type="EnsemblBacteria" id="ACU73101">
        <property type="protein sequence ID" value="ACU73101"/>
        <property type="gene ID" value="Caci_4237"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4237"/>
    <dbReference type="eggNOG" id="COG1611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159906_0_0_11"/>
    <dbReference type="OMA" id="CGSTKFK"/>
    <dbReference type="OrthoDB" id="2047795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="128" mass="14207" checksum="A7E8C5BCFAFB9C91" modified="2009-10-13" version="1">MSYRQLLTPEEKLAEAKKLLSLPHIVVICGSTRFMTEMTEADLRETKAGKIVVKPGFDMKSPHGLWSDPVEAEALKVRLGELHRAKIRLADEVLVVGDSIGDSTRAEIAYARSLGKPVRFTHPDVDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI82</accession>
    <name>C7QI82_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of SigK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sigma-K anti-sigma factor RskA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4263"/>
    <dbReference type="EnsemblBacteria" id="ACU73127">
        <property type="protein sequence ID" value="ACU73127"/>
        <property type="gene ID" value="Caci_4263"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4263"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075802_1_0_11"/>
    <dbReference type="OMA" id="VYQMWLI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="4">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25640" checksum="AF1319292CC00B13" modified="2009-10-13" version="1">MDPEVHSLTGAYVCHALEPAEREAFERHLAECPTCVQEVAELQETAALLASAAAETPPARLKAAVDARIAVTRQIPPIIDHTPARQAAPRPRRRWFTGLGYGLAAGMAVVVAVLGVRLNDQQNQIDQARERSTTISALLAAPDAHSDSVTVSTGGSGRVLVSRSRDEAAITVSGLSQLSPGKVYQLWMMGPSGARSGGLVPIGSEAFDSVLAHGLGDAQTIGLTVEPTGGSAQPTTTPVMLLPMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL3</accession>
    <name>C7QIL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794819.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6236"/>
    <dbReference type="EnsemblBacteria" id="ACU75090">
        <property type="protein sequence ID" value="ACU75090"/>
        <property type="gene ID" value="Caci_6236"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6236"/>
    <dbReference type="eggNOG" id="ENOG5032T0S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086041_1_0_11"/>
    <dbReference type="OMA" id="FFGMYGR"/>
    <dbReference type="OrthoDB" id="1952768at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025492">
        <property type="entry name" value="DUF4383"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14325">
        <property type="entry name" value="DUF4383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19614" checksum="E7E8E67827A8D4DD" modified="2009-10-13" version="1">MVRLHEHLPADHRLGQVYRWGSILSAVVLLVFGVMGLLDSIPFFGTQGQHVMGMSSNGLLSVVSIVVAVFLLVAARIGGNFASTANMVMGGVFIVAGLLGLAVMDTTANFLAFGLSNVFFSFVVGLVMMTFGMYGRVNLYLPYDNPYYQARHPEVAEVVDVAELSSAARRSKLRTIPPKTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX0</accession>
    <name>C7QIX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium:dicarboxylate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8197</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796745.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8197"/>
    <dbReference type="EnsemblBacteria" id="ACU77020">
        <property type="protein sequence ID" value="ACU77020"/>
        <property type="gene ID" value="Caci_8197"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8197"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_0_11"/>
    <dbReference type="OMA" id="AQIYGIP"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="46529" checksum="8C6A33541B711AC3" modified="2009-10-13" version="1">MSETSSPPPAPRAATPAPARSRWYRQLYFWVLVGIAAGIALGAAAPGVATQLQPLGDSFVNLIRMVITPVVFVTVVTGIAGVGKLREVGRVGVRSLIYFEVLSTVALAIGLLVMDVLRPGAGVHAKVPKATGTAAQYIKTGQTQSAWHYLTDMVPNSIVGAFSTGSVLQVLVIAVLVAVSIKLVGEPAVPVARGIEVVGKVLFQVLRIVMYAAPVGAFGAMSFTVGKYGLHTLTSLGKLIAVFYGTSALFVLVVLGAVAATQGVNILKLVRYIAPELLVVLGTSSSETVLPRIMDKMEQAGVRRDVVGLTVPAGYSFNLDGTCIYLTLGSLYVAQALDVHLSFAQQVSILGVLLLTSKGAAGVTGSGFIVLAATLSTVGTIPVAGIMLIFGIDKFMSECRALTNLCGTAVGTIVIAGWEDALDREQLSAQLNGGGEGSPEPVTSGVAIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ13</accession>
    <name>C7QJ13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Clp domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784450.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0200"/>
    <dbReference type="EnsemblBacteria" id="ACU69155">
        <property type="protein sequence ID" value="ACU69155"/>
        <property type="gene ID" value="Caci_0200"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0200"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083296_0_0_11"/>
    <dbReference type="OMA" id="TEIGKCM"/>
    <dbReference type="OrthoDB" id="1762852at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="4">
        <location>
            <begin position="95"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="29182" checksum="58F914AC6D6A779E" modified="2009-10-13" version="1">MEELPTLPVLIARIESSHPFSDPLARLADAVETGASISALADHLVGHFVDEARAAGASWAQIGVALGVSKQAVQQRFVPREPATVADFDIEVQRFSRFTPRCLNCVLGAEKIAVATGAAAVTPTHILIGLFVEPQSLAIHALADNGADPAQVRAAAVETLPPAPEGATVLATATATAPSQEPAIPGNSLPFTPEARKTFDLAVRAALSAGHNYVGTEHLLLALAGDPKSETALLLTSFGLTRDGLEASVQRLLMEFMANSGRRGSGVSPLDPAEQGAPPAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM1</accession>
    <name>C7QJM1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ordered locus">Caci_2326</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786537.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2326"/>
    <dbReference type="EnsemblBacteria" id="ACU71244">
        <property type="protein sequence ID" value="ACU71244"/>
        <property type="gene ID" value="Caci_2326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2326"/>
    <dbReference type="eggNOG" id="ENOG5032S23">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1737240_0_0_11"/>
    <dbReference type="OrthoDB" id="1975204at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU71244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="16273" checksum="D15D7B2D3876E5ED" modified="2009-10-13" version="1">MAQQTTVRGAVGPIPVRSSSARTAARIPPIAELKLGWQERGLCQSGDAAVFFAPDSERIREREKREASAKRVCDECPVRQQCLEHALALPEQFGIWGGLTEVERAEESRRRRGAATGARPVVVPIRIGTPRDRGFADAAAVTREGTEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJT1</accession>
    <name>C7QJT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792898.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4305"/>
    <dbReference type="EnsemblBacteria" id="ACU73169">
        <property type="protein sequence ID" value="ACU73169"/>
        <property type="gene ID" value="Caci_4305"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4305"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="WRTAQGN"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="30085" checksum="FDF8CC21DA696C63" modified="2009-10-13" version="1">MPGTKAEKIRLEAVTKTFEVRDGGTFTALEDVTLDVAPGEFLVVVGPSGCGKSTLLDLVSGLTKPTGGRILLDGAPVTGPALDRGIVFQQYALLPWRTALRNIEFALEAQPRLDRLSRKNRVERAREYLDLVGLSGFEDRYPHELSGGMRQRVAIARALVADPAVLLMDEPFAALDAQTREQLQEELLRIWHKTGTTVVFITHGIDEAVYLGQRVAVMTSRPGRIKQVVEVPLGDRQADDDVRSSPEFAAHRHQVWSLLRDEVTAVREVVSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK70</accession>
    <name>C7QK70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6290"/>
    <dbReference type="EnsemblBacteria" id="ACU75144">
        <property type="protein sequence ID" value="ACU75144"/>
        <property type="gene ID" value="Caci_6290"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6290"/>
    <dbReference type="eggNOG" id="ENOG502Z954">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033907_1_1_11"/>
    <dbReference type="OMA" id="WSGPRNL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26639" checksum="3AAEEA3E4420E60F" modified="2009-10-13" version="1">MLALWSAPRSRSTAFARMMAERDDRVVVHEPFSQVVDFGEVKVGGQLAHSEAGVLEVLRAIAAESPVFFKDTTDFHYPTVLADRDFLASATHTFIIRHPAEAIASHRALAPELGRDEIGFARLYELFAAVQAATGATPVVIDSDDLLDRPAQTVRAYCEAVGIPFLPEALSWEPGMRSEWQATSRWHASTSRTAGFQRAGDGDATAERARALEAVEADPVLRAHHDHHLPYYEKLRAAALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK76</accession>
    <name>C7QK76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine biosynthesis protein LysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794879.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6296"/>
    <dbReference type="EnsemblBacteria" id="ACU75150">
        <property type="protein sequence ID" value="ACU75150"/>
        <property type="gene ID" value="Caci_6296"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6296"/>
    <dbReference type="eggNOG" id="ENOG5031EJ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195720_0_0_11"/>
    <dbReference type="OMA" id="HQIVECP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005906">
        <property type="entry name" value="LysW"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01206">
        <property type="entry name" value="lysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="59" mass="6394" checksum="8E408A5B8BF5F19F" modified="2009-10-13" version="1">MITNVAQACPECEEPVELAEAVRLNEIVECAGCRSELEIVALDPPVLALAPEVEEDWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKA5</accession>
    <name>C7QKA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6325"/>
    <dbReference type="EnsemblBacteria" id="ACU75179">
        <property type="protein sequence ID" value="ACU75179"/>
        <property type="gene ID" value="Caci_6325"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6325"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_15_1_11"/>
    <dbReference type="OMA" id="IGWLVMS"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="19"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="166"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="35054" checksum="F014D8CB066AE6D3" modified="2009-10-13" version="1">MSQPTAPPAELERKGAFELTFAMILSGTIGVFVVESGASPFNVVFFRCVFGAIALGSYCLARGYFKNHGFTAKKLGLTALGGVFIVFNWVLLFSSYTKTSISVATVVYHTQPFYVVLLGAVLFRDKLTASKVGWLVVAFTGLILVAGVSASDLSGDSTYLVGLGQALLAAVFYALSTVITKRVSGVRPHLIALVQVLLGIPLLLPFAAVGQTADLGARWGWLVGIGLIHTGVMYVLMYSAYQKLPTPKIAVLAFIYPAMAMVMDWLVFGHHVSVVQALGIPLIVTASLGVNLGWRFGPPRRRTPAEQTPSVPETKTAQLVPATSTGGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ3</accession>
    <name>C7PVJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784644.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0397"/>
    <dbReference type="EnsemblBacteria" id="ACU69349">
        <property type="protein sequence ID" value="ACU69349"/>
        <property type="gene ID" value="Caci_0397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0397"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_612386_0_0_11"/>
    <dbReference type="OMA" id="AMRCRIN"/>
    <dbReference type="OrthoDB" id="1869225at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="364"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="475" mass="50765" checksum="098DC01DFE086E84" modified="2009-10-13" version="1">MPLSGDGQQTQGQIGARLQEVRTRRGLTQRALAEPGYTAAYVSTLEAGKARASEAALRYFAERLAISYEELATGVPAGLRAEIRDGLAEANAAMDAGRAAEAEALLAALLERAAGNDVPDLAADVRVALGAFLLRRGDLAAGREQFEQAEALLADRPLVARVRAIRGRATAYYLEGDVRYSCYLLENTISELNGGGLPDPASLVLLYAAVIGPYLELGALERATKAATLALDLAPRVADPIAVATLHRSVARTLAAGGRFDEAEAALVKAQDVYQQWEIRAELAQCHWMRGYLYAQHERFADAETELRTAATMLRAADAVFYAVQVEVELADVRWRLGHTDEAEHLLTRLLADLGPGHGAVHAAAAHRLLGLIRERADDPQTAERHYRQAIELQQDADVAGDLADTSRLLGDLLDKQGRTREAVAAYRNGLTALARPGTTTLGAAPLPPPVISALDSVHRAVHVVPGGGDSAAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW59</accession>
    <name>C7PW59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4443"/>
    <dbReference type="EnsemblBacteria" id="ACU73307">
        <property type="protein sequence ID" value="ACU73307"/>
        <property type="gene ID" value="Caci_4443"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4443"/>
    <dbReference type="HOGENOM" id="CLU_923431_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32005" checksum="7EFE6AC792672948" modified="2009-10-13" version="1">MADPSAPEREAMRALAARVGDRANALAAEGCVAEVPALWETAIAGLSDKSSQALITLAYAWYQALHGEVEHGVRLAADLRDCAVSSVRSQVRVLIRNRVRVEPEVVERTWRAATGIPLPAWAFLSDADIDDVAEWIAASSWEESRALYGALAGRVTSQDIEYVLDEIVLGDVRLRTAVSVHRAVLVLGGDVGYRCLGDLPEVARVAGAAIVARDWNVLRACGTVELIVHGRAFLGGVHGVIAELMAAGDMAVSPAMAERVAALARDAQPWERRQVAADLAATGDVAMLGLVVGTDAESLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH9</accession>
    <name>C7PWH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kojibiose phosphorylase</fullName>
            <ecNumber evidence="8">2.4.1.230</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.230" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794988.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6405"/>
    <dbReference type="CAZy" id="GH65">
        <property type="family name" value="Glycoside Hydrolase Family 65"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75259">
        <property type="protein sequence ID" value="ACU75259"/>
        <property type="gene ID" value="Caci_6405"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6405"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006285_2_2_11"/>
    <dbReference type="OMA" id="EAYCIPF"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033831">
        <property type="term" value="F:kojibiose phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017045">
        <property type="entry name" value="Malt_Pase/Glycosyl_Hdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036289">
        <property type="entry name" value="Glycosyl_hydrolase_malt_phosph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_hydro_65N" evidence="7">
        <location>
            <begin position="16"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="5">
        <location>
            <begin position="327"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65C" evidence="6">
        <location>
            <begin position="700"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="361"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="592"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="760"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="784" mass="85980" checksum="D77B5D07654FC4CB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWN7</accession>
    <name>C7PWN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6466</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795046.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6466"/>
    <dbReference type="EnsemblBacteria" id="ACU75317">
        <property type="protein sequence ID" value="ACU75317"/>
        <property type="gene ID" value="Caci_6466"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6466"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_0_11"/>
    <dbReference type="OMA" id="YAFRINE"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="80"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="28560" checksum="D796043687733646" modified="2009-10-13" version="1">MTGQESATVGASQYRERNSTADRALDILGLFSESRLSVSGQEVATALGAARSTAYRYLQSLVASGFLEEDPAGGFRLGVRILELARLARRGYGLSEIALPVMNDLCAEVGETVLLTRRSGSAAVCIERCEAQQPVRISYERGSVLPANAGASALALLAWLPEQQCRQELAGQRLQRFTARTITDVETLMERLAKIRRDGYSVSRGELDTDILGIAAPVRGASGEVVAAVSIAALEHRVPDRRLDDVVTALREAAELMSSRLAVIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXE4</accession>
    <name>C7PXE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0558"/>
    <dbReference type="EnsemblBacteria" id="ACU69495">
        <property type="protein sequence ID" value="ACU69495"/>
        <property type="gene ID" value="Caci_0558"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0558"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020070_0_0_11"/>
    <dbReference type="OMA" id="RHQGLRQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016137">
        <property type="term" value="P:glycoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="691" mass="72890" checksum="FE1C6BE24CE203AE" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT6</accession>
    <name>C7PXT6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793125.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4533"/>
    <dbReference type="EnsemblBacteria" id="ACU73396">
        <property type="protein sequence ID" value="ACU73396"/>
        <property type="gene ID" value="Caci_4533"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4533"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065805_0_0_11"/>
    <dbReference type="OMA" id="APMADGW"/>
    <dbReference type="OrthoDB" id="1757137at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="189"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="30400" checksum="34F457BC7F3A3E9D" modified="2009-10-13" version="1">MVNNLAIRLEHAVEAVGRNESLGGVSDRWAGLASTLTRDRKLKSLLSGSWLGHPLHPLLTDLPIGAYSMASIIDVTAGGAGAAAARRLVGLGLITTVPTAAAGASDWSDTHGPTQRVGLVHGLLNVTATLTQTASWVARRRGRRGTGMALSGLGLGLTAVAAYLGGYLSYSRGVGVDHTAFQPTVAEWTDVAAAGDLTEEHPLRGEADGVPVVLVKLRGAVYALSATCTHAGGPLDEGMIVDGDCLRCPWHGSVFRLADGGVVRGPAAAAEPCWEVKVENERIQVRSAQPAGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ3</accession>
    <name>C7PXZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793182.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4591"/>
    <dbReference type="EnsemblBacteria" id="ACU73453">
        <property type="protein sequence ID" value="ACU73453"/>
        <property type="gene ID" value="Caci_4591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4591"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1132678_0_0_11"/>
    <dbReference type="OMA" id="WWLRNTG"/>
    <dbReference type="OrthoDB" id="1812435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="29126" checksum="9633CC4441932893" modified="2009-10-13" version="1">MQIRDFIPQVLPQDLPSLAGGVPPAPAGTIFVKAGPSGFAVPPRKFTLHFGRAEADVHVVIGGDDEFVSRLAGVFTCDGDEWWLRNEGRRPILMPGTEPVLRHHEVTVGPGYTPLTIETPNRRTHLLEVHIVGTPGRRPGDVGQARTLTSDVTDLSPVERLMLIALGQRYLRREPYPAPVTWKQAADDLNEAQPNPVHPWTAKAVERRISELRARLSTGPGAIRGIVKEPGMVEPLGNTLNDNLIRALLRNATLVPEDLYALGENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ5</accession>
    <name>C7PXZ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793184.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73455">
        <property type="protein sequence ID" value="ACU73455"/>
        <property type="gene ID" value="Caci_4593"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4593"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1033230_0_0_11"/>
    <dbReference type="OMA" id="ANNDTIP"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982667" evidence="3">
        <location>
            <begin position="29"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="153"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28132" checksum="87AFB0F606B3420C" modified="2009-10-13" version="1" precursor="true">MQCHKPGHRARARCVSALLAAGALLAAAADHLGGTSERPAVHTAALGIPSALSTASIPALLTGVQAPAPVARRVQPAKTVRKTAKTTKPTKTIKSSKATKTVKTVKTSKTPAQHKSASRPASNSKPRSNSRSRPAPVRHTNSYLLAHLPPAKNKKAAAAVHEALALIGVPYRWGGTTRAGFDCSGFTQHVWGVAGVKIPRTVRAQAKAGTHISLNKAEPGDLVVFYPAQHHVGIYVGNGLVIDSPHTGAKVRPDPVRSMPVSVVVRVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY42</accession>
    <name>C7PY42_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4641</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793231.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4641"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73502">
        <property type="protein sequence ID" value="ACU73502"/>
        <property type="gene ID" value="Caci_4641"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4641"/>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013093_3_3_11"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982601" description="Alpha-galactosidase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="444"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="574" mass="58815" checksum="66BC393FED6FFB0A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY53</accession>
    <name>C7PY53_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793242.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4652"/>
    <dbReference type="EnsemblBacteria" id="ACU73513">
        <property type="protein sequence ID" value="ACU73513"/>
        <property type="gene ID" value="Caci_4652"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4652"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="DANCCAV"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="43969" checksum="E28B30F9814E8824" modified="2009-10-13" version="1">MHSTAGDTQAAPQTPINLHNLGRVRILQALTSHARLSRADLVRHTGLARTTVSSVIFDLISAGLVRESPDVRENSDTAAAAAAGAAPGQRTGRPPLLLRLEPEAAYAVGLDVGHDHVRAIVTDVVGTPRWDRTEALAVDDDPRRALDTAVRLIAEAVKDTAVPPHKILGLGLGIACPVDKTTGGLHAEGIMPGWVGTRPADDLAERTGLPTQIINDANAGVLAERRFGAAREATNVVYVRLAAGIGAGMMSEGRMLLGHHGLAGELGHVMVELNGAVCRCGSRGCLETVASPAAIAGLLARSWGQPADSIDLPELLRRGDRGALRVVEDAGEAVGRALSAAVQLLNPQLVVIGGDLAEAGEALLEPIRRTLRRGTMGSLNQRLRIVPSTLGDSAGVRGAAALVLDSVPQRLALDLPARGDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYD0</accession>
    <name>C7PYD0_CATAD</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">Caci_6574</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6574"/>
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        <property type="gene ID" value="Caci_6574"/>
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    <dbReference type="HOGENOM" id="CLU_017620_0_0_11"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="619"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="826" mass="89836" checksum="44A66C7F5A08F6C2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYD6</accession>
    <name>C7PYD6_CATAD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ordered locus">Caci_6580</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
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            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6580"/>
    <dbReference type="EnsemblBacteria" id="ACU75426">
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        <property type="gene ID" value="Caci_6580"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6580"/>
    <dbReference type="HOGENOM" id="CLU_1977568_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="13960" checksum="A366708CDC3D97D2" modified="2009-10-13" version="1">MSGKPRNYQGIVYAEAHALLRRTLEWEFPERRWNRVDDALAGMESALDGGSLQTFEDTVATMELLAPPRVSTRLGDRPVVPAPARVRERVNKLIERLVRLVDDADADDAEDAADDTGLSQTADPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYI8</accession>
    <name>C7PYI8_CATAD</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ordered locus">Caci_8487</name>
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    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797035.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8487"/>
    <dbReference type="EnsemblBacteria" id="ACU77310">
        <property type="protein sequence ID" value="ACU77310"/>
        <property type="gene ID" value="Caci_8487"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8487"/>
    <dbReference type="eggNOG" id="COG3774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_223298_0_0_11"/>
    <dbReference type="OrthoDB" id="210518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2636"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2878"/>
            <end position="2915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2980"/>
            <end position="3003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3342"/>
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        </location>
    </feature>
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        <location>
            <begin position="3560"/>
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        </location>
    </feature>
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        <location>
            <begin position="3672"/>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="3942"/>
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        </location>
    </feature>
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        <location>
            <begin position="4719"/>
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        </location>
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        <location>
            <begin position="707"/>
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        <location>
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    </feature>
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        <location>
            <begin position="2895"/>
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        </location>
    </feature>
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        <location>
            <begin position="2980"/>
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    </feature>
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        <location>
            <begin position="3362"/>
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        </location>
    </feature>
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        <location>
            <begin position="3795"/>
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        </location>
    </feature>
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        <location>
            <begin position="3836"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3958"/>
            <end position="3980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="5128" mass="555003" checksum="1568A6C0CF95191F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYW4</accession>
    <name>C7PYW4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="7">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmI</name>
        <name evidence="9" type="ordered locus">Caci_0583</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784815.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0583"/>
    <dbReference type="EnsemblBacteria" id="ACU69520">
        <property type="protein sequence ID" value="ACU69520"/>
        <property type="gene ID" value="Caci_0583"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0583"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_0_0_11"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="11"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="30846" checksum="5DD09CC799AA945F" modified="2009-10-13" version="1">MTGTEPTPGLLVLAGTPIGQDEDASPRLAAELTAADVIATEDTRRLKRLLRVLDLTPKARFVSYFEANESARTPDLLRDLLAGARVVVVTDAGMPSVSDPGYRLVAAAVEAGVRVTAVPGPSAVLTALAVSGLPVDRFCFEGFLPRKGGGRSSRLTELSSEPRTMVFFEAPHRLAASLADMAAALGTDRPAAVCRELTKTYEEIKRGTLADLAKWAADGEIRGEITVVVGGALPGAGRDLSGAEIAELVFARETAGGLRRKEAIAEVAAELGLPKRDVFDAVVAAKEAAEAADES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX5</accession>
    <name>C7PYX5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784826.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0594"/>
    <dbReference type="EnsemblBacteria" id="ACU69531">
        <property type="protein sequence ID" value="ACU69531"/>
        <property type="gene ID" value="Caci_0594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0594"/>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_12_0_11"/>
    <dbReference type="OMA" id="GTDIGRQ"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="140"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="45344" checksum="66002F1D0D39848F" modified="2009-10-13" version="1">MARHEVWAELARLKDTTRFYDAVIEEQDRKEPRRIRIGDHWLSDFASCNYLGFDVDPEIMAAPAELIAKWGTHPSWSRLLGNPKPYLDIEDQLTDLLQAPDTLVLPTITHIHMTVIPVLAGKGTVFCEAQAHRTIYDGSSVARGNGATLHRWRATDLGGLAIALRKAPKDLPRLVCMDGINSMSGNEPGLAAIADICRAEGALLYVDDAHGFGVIGERSEAETSPYGALGNSIVRHLGESYEGLVLVGGFSKAYSSLLAFLALPTQMKEYLKFAAAPYLYSGPSPTASLATVLAGLKVNRERGEEIRGRLWHKTARVIDHVRKLGLSTPNVSGFPIIELPAREPSDIDAIATILWERGIYVTLAAYPLVPRDQAGFRIQVTAANTDEEVEQLNATLTELAPMLRPADRHRAPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ51</accession>
    <name>C7PZ51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0671</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784902.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0671"/>
    <dbReference type="EnsemblBacteria" id="ACU69607">
        <property type="protein sequence ID" value="ACU69607"/>
        <property type="gene ID" value="Caci_0671"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0671"/>
    <dbReference type="HOGENOM" id="CLU_2080534_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="117" mass="11721" checksum="4CCBE532F3C08477" modified="2009-10-13" version="1">MNAVSGLLTPAQPLLAGSGSLDKTKPGLVAFLIVLALGVALWALLKNMGKQLGRAKDHFEAEDAALAAEAAVAPTPVPTPAGKAEAVADVPKQDGPKSATGKTKPKAKDATKDAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ94</accession>
    <name>C7PZ94_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2634"/>
    <dbReference type="EnsemblBacteria" id="ACU71551">
        <property type="protein sequence ID" value="ACU71551"/>
        <property type="gene ID" value="Caci_2634"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2634"/>
    <dbReference type="HOGENOM" id="CLU_1999793_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="13203" checksum="83ECDAA2281374B4" modified="2009-10-13" version="1">MSSPRGQRSPEPTAAPGDAVQMAEQLVAGAWMAELYAAVHDAEAALRAALHLRATARAKVRAAQRAGDPERIVEAQRELELTEHDLAEADATFSGVSELLARELNDQPSATRVRILPNLPATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q016</accession>
    <name>C7Q016_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795238.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6663"/>
    <dbReference type="EnsemblBacteria" id="ACU75509">
        <property type="protein sequence ID" value="ACU75509"/>
        <property type="gene ID" value="Caci_6663"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6663"/>
    <dbReference type="eggNOG" id="COG0775">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108049_0_0_11"/>
    <dbReference type="OMA" id="FFEWHRS"/>
    <dbReference type="OrthoDB" id="2038138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22847" checksum="9EAE79439EF65C0D" modified="2009-10-13" version="1">MTDLLVCAALGIEARALKTDGLRVERVGMGVRRAEEFARRERAFDVLAVAGFGGATDECLRPGDIVVADEVRRGGQVIECPWADSIAFALERHLILEPEVDEAPEPHTAHGLNAAGRGTPAVMTGPVETIDHIASAQILTRLAGQGVTTVDMESFPLVATARGRPFTVVRVIVDTPDHPLVRPSTLRAGLNARKRLQAIGAVLRDWATALEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0K9</accession>
    <name>C7Q0K9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0702</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784932.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69637">
        <property type="protein sequence ID" value="ACU69637"/>
        <property type="gene ID" value="Caci_0702"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0702"/>
    <dbReference type="eggNOG" id="COG1714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1472669_0_0_11"/>
    <dbReference type="OrthoDB" id="1884726at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="7">
        <location>
            <begin position="77"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="19674" checksum="1632C20F611ABA5E" modified="2009-10-13" version="1">MTQPQYPDAPPPGQGNQYTPGYQGMPQAPPIPAGYGYGAPQMNVPPGMYYDPNSELVLPQGVELASVGRRIGAYFLSIVLVVVTLGVGYLIWGLIAWGKGRGPTQQVLGMRCWTPNNGRVAGWGTMALRNIVGGIVQGILSFVTMLVSFVLFLSGKQHKTLPDLVGSTVVLYDPNNILENWQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q167</accession>
    <name>C7Q167_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2833"/>
    <dbReference type="EnsemblBacteria" id="ACU71742">
        <property type="protein sequence ID" value="ACU71742"/>
        <property type="gene ID" value="Caci_2833"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2833"/>
    <dbReference type="HOGENOM" id="CLU_2205299_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="12147" checksum="6DF1E76A93DD4ACA" modified="2009-10-13" version="1">MQIDAALNFVALVAPLVLSYCVAGATLRGLRAWRRHAWRARLEQQPFHPRMLPTLGQHTATGLSGLTPDAWYANLADDAIKGRRRRGPSWLDYLEEFHPEKGAWRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q187</accession>
    <name>C7Q187_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2853</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2853"/>
    <dbReference type="EnsemblBacteria" id="ACU71762">
        <property type="protein sequence ID" value="ACU71762"/>
        <property type="gene ID" value="Caci_2853"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2853"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_482901_0_0_11"/>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="262"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="331"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="461"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="504"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="469"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="564" mass="60622" checksum="3583D1CA5B769410" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q197</accession>
    <name>C7Q197_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2863"/>
    <dbReference type="EnsemblBacteria" id="ACU71772">
        <property type="protein sequence ID" value="ACU71772"/>
        <property type="gene ID" value="Caci_2863"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2863"/>
    <dbReference type="HOGENOM" id="CLU_1394139_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="20913" checksum="521074AFF1CFF55D" modified="2009-10-13" version="1">MSTERDQRRATALANATALFTGLGTREIEDRPARSSRTIGRRVTEVADWFEHWLSRPAPIATVEAVFGTPEPRNTEGHPMAFSMPDNDMVTVTLTAFDDEKVPVPTDFSDPNGDFVAPFTWVEDNTDLGEVAVAEDTLSANVRSHPGQAGLLTLNITDVNGKAMAPVTVQIDPGAATSVGAVFGQPVPRDDNPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D8</accession>
    <name>C7Q1D8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793396.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4806"/>
    <dbReference type="EnsemblBacteria" id="ACU73667">
        <property type="protein sequence ID" value="ACU73667"/>
        <property type="gene ID" value="Caci_4806"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4806"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_0_0_11"/>
    <dbReference type="OMA" id="VGQIYNT"/>
    <dbReference type="OrthoDB" id="1629615at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018309">
        <property type="entry name" value="Tscrpt_reg_PadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10400">
        <property type="entry name" value="Vir_act_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Vir_act_alpha_C" evidence="3">
        <location>
            <begin position="91"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="21910" checksum="DD2E3CBF8869A717" modified="2009-10-13" version="1">MSVKHSLLAGLAGGERYGYQLRAEFEERTGATWPLNIGQVYTTLARLERDGFVEAAGEDVQGHVFYRITDAGREELLGWFARPVTRAERPRDELAVKLALAVTVDGVDVPAIVHAQRKHALGALQDYTRVKTRLAPEELAAGLVLESMVFQCEAEIRWLDHVEARVMRHARTLPAATRAGSAASVPTEPPTAAAREGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1W2</accession>
    <name>C7Q1W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795391.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6822"/>
    <dbReference type="EnsemblBacteria" id="ACU75663">
        <property type="protein sequence ID" value="ACU75663"/>
        <property type="gene ID" value="Caci_6822"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6822"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_5_1_11"/>
    <dbReference type="OMA" id="LGRSAWY"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="667"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="204"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="741" mass="76187" checksum="CE7AD478899463AE" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Z9</accession>
    <name>C7Q1Z9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797260.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8721"/>
    <dbReference type="EnsemblBacteria" id="ACU77536">
        <property type="protein sequence ID" value="ACU77536"/>
        <property type="gene ID" value="Caci_8721"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8721"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_8_0_11"/>
    <dbReference type="OMA" id="LMLIAYD"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="166" mass="17309" checksum="7EA45F00ABD0EFB4" modified="2009-10-13" version="1">MAGTLLIAYDGSADAKTALEYTARTFPGREAVLLTVWEPLMSQLGVAEAFVGAVATEDEEKVVELSAEQVAEAGAQLAGEAGLKATARWESEGTQSVWQTIERVADELDADLVVTGSRGLTGLHSLLVGSVSAKVLRHAQRPVLVVPSAHLAKARSEAPEGDSADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q204</accession>
    <name>C7Q204_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8726</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8726"/>
    <dbReference type="EnsemblBacteria" id="ACU77541">
        <property type="protein sequence ID" value="ACU77541"/>
        <property type="gene ID" value="Caci_8726"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8726"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_2_0_11"/>
    <dbReference type="OMA" id="GAIITHC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982436" evidence="2">
        <location>
            <begin position="33"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="105"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="31588" checksum="5FF7C8326BA35BB8" modified="2009-10-13" version="1" precursor="true">MIRPLLSRFPARKHRTQTIAAVAVLGAVGVAATACGGGGAGGAGGGAGGRAASATGGSSAPSTSEARPSSPSSLSSPSSPASPSSPSSPTPSPRTNADVDCSVAKCIALTFDDGPGPDTGRLLDVLKAQNVPATFFVLGDQAVKYPSLVHREYAEGNEVGNHTWDHKDLSRLPAAAVQDEITRSADAIAATGIPRPTLVRPPYGAVDDTVRTVAGAPFIMWRVDPEDWKYPDPARVADQIVGHAKPGRIVLSHDTHKTTVDATPAVIQRLKHQGYTFVTVSTLMKGVGLRNGTSYFNRPPAITGGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q259</accession>
    <name>C7Q259_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8781"/>
    <dbReference type="EnsemblBacteria" id="ACU77596">
        <property type="protein sequence ID" value="ACU77596"/>
        <property type="gene ID" value="Caci_8781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8781"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="HETVRWD"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045981">
        <property type="entry name" value="DUF5937"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19361">
        <property type="entry name" value="DUF5937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="245"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="35882" checksum="66FEFB79DD946CB5" modified="2009-10-13" version="1">MANPIRIPIAGTEMARVRFAISPVYEALQAVDVLVEPGKHAVHLPWVRWARPLLAQVPDVEILSGFTGRAVRPGVLVPPPDVHMPALEEELETIRTAESWRVRRYFENNGMPSDRFQREFYDDPPAGLARLADVLRRVFDVLVAPHWPRMIGVLEADIAYRARVLADGGVAAVFDDLHHDVRWSDSELRLHGPGISEAVWPFAAKEVVLEGRSLVLSPTVLGWPNICVATKPVTAGLLHYPARAVATVWETRRPAPDALAALLGRTRAELLVQLAAPGTTGELAGRLGVTAGAVSQHLGVLRGAGLVATRRDGRAVLHLRTERAEALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q267</accession>
    <name>C7Q267_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797328.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8789"/>
    <dbReference type="EnsemblBacteria" id="ACU77604">
        <property type="protein sequence ID" value="ACU77604"/>
        <property type="gene ID" value="Caci_8789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8789"/>
    <dbReference type="HOGENOM" id="CLU_958750_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="30202" checksum="BF79D251D0430B32" modified="2009-10-13" version="1">MSTDELRSGGSGSEIHDLLGTAFDDGVPVLNLVPGAVDGYRKHRRRTRVLGTVGGALALAAVAVTGTVLGAGGGHQAQTTTGSGPNPVSAKTVMRCTGKYQLIGSYGGGLGVYSADQQRLTAVCEQDLTTLQQLIGDPSLGPLAESITPAPGLFSSMPTSEMTPQVGGSGALLQPGQYLGESVDGRDYDLSIEVFDKIPSLGGNCTSKSCPPNLKLADGRPATKVTGVLRDHYVVIHYDATHTVEIRAGLENRNSDEPLPFDFDQLIASPALARLISSDVHTLDLLNHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2B2</accession>
    <name>C7Q2B2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase, P-type (Transporting), HAD superfamily, subfamily IC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8836</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8836"/>
    <dbReference type="EnsemblBacteria" id="ACU77649">
        <property type="protein sequence ID" value="ACU77649"/>
        <property type="gene ID" value="Caci_8836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8836"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_5_1_11"/>
    <dbReference type="OMA" id="RLGRKQC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="601"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="722"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="755"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="794" mass="83371" checksum="65FF5A7F863F4449" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2H7</accession>
    <name>C7Q2H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-L-fucosidase</fullName>
            <ecNumber evidence="6">3.2.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0886</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0886"/>
    <dbReference type="CAZy" id="GH29">
        <property type="family name" value="Glycoside Hydrolase Family 29"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69819">
        <property type="protein sequence ID" value="ACU69819"/>
        <property type="gene ID" value="Caci_0886"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0886"/>
    <dbReference type="eggNOG" id="COG3669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_0_3_11"/>
    <dbReference type="OMA" id="LPEHKWE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="PTHR10030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001092">
        <property type="entry name" value="Alpha-L-fucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="site" description="May be important for catalysis" evidence="5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001092-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="45708" checksum="B67664AB309B2F85" modified="2009-10-13" version="1">MQPWFADAKLGIFVHWGIYAVNGIPESWSFYNGEITYENYMKQLEGFTASAYDAGEWARLFKAAGARYAVLTSKHHDGVALWETAENDLNVVQRTPAGRDLLAPYAEAMREAGLKVGLYFSHLDWSHPDYPFHSREEFEGGTVAEDPEAWARFLAFHRAQLKEIVEGYAPDLLWFDGDWERPEEQWRMAELREQLTGMKADMVFNSRLLGHGDYATPEQGAPITPPEGPWELCYTVNNSWGFQRNDQDHKPLSLLVRTFVETISGGGNLLLDVGPRADGSIPSEQTARLEALGRWIRRNEPAIYGTVRGIPAGHVYAPTTLSADRRTLYVFCHDPPRDPVTIKGLTSRVKRVTALATGEELTHRRYGGFDTIPAVLAIDPPSAADPVVTVLALELEGEVELYRGEGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V5</accession>
    <name>C7Q2V5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787140.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2938"/>
    <dbReference type="EnsemblBacteria" id="ACU71847">
        <property type="protein sequence ID" value="ACU71847"/>
        <property type="gene ID" value="Caci_2938"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2938"/>
    <dbReference type="HOGENOM" id="CLU_2732612_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="71" mass="7841" checksum="8E5F8BFCDFE75221" modified="2009-10-13" version="1">MGTVALCCWRCCSMNSGPDAVVIWQLTPDDYALGYCGGCLDLMLDEVDRRELLEPSRLDFLIEPGKLMAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3J9</accession>
    <name>C7Q3J9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M78 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6931"/>
    <dbReference type="EnsemblBacteria" id="ACU75764">
        <property type="protein sequence ID" value="ACU75764"/>
        <property type="gene ID" value="Caci_6931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6931"/>
    <dbReference type="eggNOG" id="COG2856">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098656_1_0_11"/>
    <dbReference type="OMA" id="HEDEANW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M78" evidence="1">
        <location>
            <begin position="74"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20933" checksum="D16AF62F41C8F2C6" modified="2009-10-13" version="1">MRRGFKTEAERLAERQRAQLGLQPVDPLKIFDLAENLGVRVYSASDLVDRSALEELERLQPGAFSAATFNMPDGDTVAVYNPLSEPGRTNSDIAHELAHILLGHRLRDLQKIGGNTFFACDPEQEEEANWLAGCLLLPRPLLLREAYAKATPEAIAHKYHVSISMARFRLNASGVMMQARRSPQRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3N9</accession>
    <name>C7Q3N9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795532.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6974"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75804">
        <property type="protein sequence ID" value="ACU75804"/>
        <property type="gene ID" value="Caci_6974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6974"/>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_312534_0_0_11"/>
    <dbReference type="OrthoDB" id="351769at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015925">
        <property type="term" value="F:galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980579" evidence="6">
        <location>
            <begin position="32"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="9">
        <location>
            <begin position="502"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="641"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="740"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="8">
        <location>
            <begin position="828"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="623"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="938" mass="95629" checksum="FA810F72D821AE30" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q445</accession>
    <name>C7Q445_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">6-phosphofructokinase</fullName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0974</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785199.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0974"/>
    <dbReference type="EnsemblBacteria" id="ACU69905">
        <property type="protein sequence ID" value="ACU69905"/>
        <property type="gene ID" value="Caci_0974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0974"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_7_4_11"/>
    <dbReference type="OMA" id="PYIDQSF"/>
    <dbReference type="OrthoDB" id="1421302at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012004">
        <property type="entry name" value="PyroP-dep_PFK_TP0108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000534">
        <property type="entry name" value="PPi_PFK_TP0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="9">
        <location>
            <begin position="89"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="439" mass="47064" checksum="C7000BC4D5C693EC" modified="2009-10-13" version="1">MNTADLLTITSDDLAITRLGERTVDTPLSDLLGERQETWHYVTETDRVMLDVVQGIANKRDVDVAGLPAFNPGGPRRKLFFEPSEVTAAIVTCGGLCPGLNNVIRGLVLHLGRAYGVKRVLGFRNGFKGLTDGSEPMELTEQSVADIQNRGGTILGTSRGNQDPVVAVDSMVRLGVNILFVIGGDGTLRGASKLADEARARGERIAVVGIPKTIDNDIPWIDRSFGFHTAFAQAAQSIRAAHIEASSTENGVGLVKLMGRHSGFIACYSTLASHDVDFTLIPEVPFDVDVLMSRLKKKVEAQGHAVVVVAEGAGQEHFPASDQTDASGNAKLNDIGALLKKRIIDAFGDEPLSVRYVDPGYEIRSVPANAFDAVYCTRLAQAATHAGMAGFTSMVVGQWSGRMVHLPIALATASRNVVDPHGQLWMNVLETTGQPKQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4E2</accession>
    <name>C7Q4E2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1076"/>
    <dbReference type="EnsemblBacteria" id="ACU70002">
        <property type="protein sequence ID" value="ACU70002"/>
        <property type="gene ID" value="Caci_1076"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1076"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_0_1_11"/>
    <dbReference type="OMA" id="TARWCSM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="128"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19344" checksum="0D9F667FD0C58822" modified="2009-10-13" version="1">MSTTAMTAAVPADEQLLLNLLNTTPVIDGRELDELGDLASARRWLAANGLEKSESEWRGLLELRPILQAIVRGEQSPRALAPFLEGVGYSPRATPEGLDWALHAPEGRITAAKAVLAWDALRISSPGRLRACANTECQLFLIDRSKPNSAKWCSMAVCGNRMKARRHYHRAGETAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H1</accession>
    <name>C7Q4H1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ParB domain protein nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3031"/>
    <dbReference type="EnsemblBacteria" id="ACU71940">
        <property type="protein sequence ID" value="ACU71940"/>
        <property type="gene ID" value="Caci_3031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3031"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902217_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33703" checksum="1B99EB5C86C678EB" modified="2009-10-13" version="1">MPIANITIGTRCRKDLGKLRDLQRSIRVAGLLTPIPVTADGQLIAGERRLRACRNLGWERVPVIVAANGAHAIDLIRAEHNNGPHSLPMSATELTRLGMRIEEHGHELAVANRAHGHSTLPDDIRVNLRALASEIIQMPEHHYSRVKTLVLAAAGVQSTPGGYDTSTIAPDARNAAREALELVDRVYAGEEIRVPGLRVRLSTARIYKNWVGTYRHIQEPLDNVAKGDKAALQEPLVKVRTMRIDQREALAKGLSALTGLCHGLASINSIDPAMTREEAASFERDLSNASRVLRGLHNKIKEYANGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J7</accession>
    <name>C7Q4J7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787259.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3057"/>
    <dbReference type="EnsemblBacteria" id="ACU71966">
        <property type="protein sequence ID" value="ACU71966"/>
        <property type="gene ID" value="Caci_3057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3057"/>
    <dbReference type="HOGENOM" id="CLU_1755551_0_0_11"/>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16709" checksum="DCD407DD5826B5BD" modified="2009-10-13" version="1">MTDGETGSGQQFSAWLKRHIDLRGVRTTDVIRAGVEAKAFSKVTFYRWYNGEHIPNSDNAKFLAEYFGVDPRNAYEAAGLTHLMDMEGDIVTAADPVEVFVARVRARGFPKPVEDRLIEYVRAEIEERKAALDKMLDAVEDTQKLQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Y9</accession>
    <name>C7Q4Y9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793666.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5077"/>
    <dbReference type="EnsemblBacteria" id="ACU73937">
        <property type="protein sequence ID" value="ACU73937"/>
        <property type="gene ID" value="Caci_5077"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5077"/>
    <dbReference type="eggNOG" id="COG4257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_298041_0_0_11"/>
    <dbReference type="OrthoDB" id="138374at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032109">
        <property type="entry name" value="Big_3_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025141">
        <property type="entry name" value="DUF4082"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16640">
        <property type="entry name" value="Big_3_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13313">
        <property type="entry name" value="DUF4082"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980596" evidence="2">
        <location>
            <begin position="33"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="Big_3_5" evidence="5">
        <location>
            <begin position="389"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Big_3_5" evidence="5">
        <location>
            <begin position="486"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4082" evidence="4">
        <location>
            <begin position="582"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="Big_5" evidence="3">
        <location>
            <begin position="739"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4082" evidence="4">
        <location>
            <begin position="857"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1009" mass="102373" checksum="159C07C86DC3EC17" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q507</accession>
    <name>C7Q507_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5095"/>
    <dbReference type="EnsemblBacteria" id="ACU73955">
        <property type="protein sequence ID" value="ACU73955"/>
        <property type="gene ID" value="Caci_5095"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5095"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465967_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="307"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="418"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="446"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU73955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="585" mass="60300" checksum="FF7B2C5D9BA99236" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5F5</accession>
    <name>C7Q5F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7094"/>
    <dbReference type="EnsemblBacteria" id="ACU75924">
        <property type="protein sequence ID" value="ACU75924"/>
        <property type="gene ID" value="Caci_7094"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7094"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_11"/>
    <dbReference type="OMA" id="GDHTSYV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="18"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="491" mass="52102" checksum="68663D29AD93AD37" modified="2009-10-13" version="1">MHQYIGGSQTAGSSGVVHQVTNPADGSGVADLVLADARDAGLAVDAAKRAYPGWSRATPAERSTALHRLAQLLDERAQEFAETESRQTGKPIRLTTGFDVPGTVDNTAFFAGAARHLEGKAAAEYSADHTSTVRREPIGVVASIAPWNYPLQMAAWKILPAIAAGNTIVLKPAEITPLTALLFAQACTDAGIPDGVVNVVVGTGPVAGEALMTHPDVRMVSFTGSTPVGKRVMELASRTVKRVHLELGGKAPFVVFDDADLEAAIHGAVAGSLINTGQDCTAATRAYVHRSRFEEFVAGVADLYATVKLGDPFDPATDLGPLVSYRQRDSVAGFVDRARGYGAKIVVGGEAPGGDLAAGAYYRPTLVTGVAQDSEIVRDEVFGPVLAALPFDTDDEAFALANDTPYGLAASAWTRDHHRALRAVREIAAGCVWVNDHIPIISEMPHGGYKSSGFGKDMSSYSFEEYTQVKHTMHDLTGVARKPWHRTIFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5N5</accession>
    <name>C7Q5N5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_9033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797570.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9033"/>
    <dbReference type="EnsemblBacteria" id="ACU77846">
        <property type="protein sequence ID" value="ACU77846"/>
        <property type="gene ID" value="Caci_9033"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9033"/>
    <dbReference type="eggNOG" id="ENOG5032SQA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150044_0_0_11"/>
    <dbReference type="OMA" id="FPHAVQW"/>
    <dbReference type="OrthoDB" id="1893426at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014447">
        <property type="entry name" value="UCP006909"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006909">
        <property type="entry name" value="UCP006909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="11396" checksum="C18E7D0462DD9914" modified="2009-10-13" version="1" precursor="true">MIFKRIGEGRPYPDHGRSFKEWAEVAPRQIRLDQLITTKRHLDLDALLSQDSTFYGDLFAHVVHWRGGYYLEDGLHRAVRAALQQRTVLHARVLDLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Q8</accession>
    <name>C7Q5Q8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ordered locus">Caci_9056</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797593.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9056"/>
    <dbReference type="EnsemblBacteria" id="ACU77869">
        <property type="protein sequence ID" value="ACU77869"/>
        <property type="gene ID" value="Caci_9056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9056"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_1_11"/>
    <dbReference type="OrthoDB" id="2069770at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="45" mass="5282" checksum="6E919E265C029CEF" modified="2009-10-13" version="1">MSKRTFQPNNRRRAKTHGFRLRMRTRAGRAILANRRAKGRSELSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5S1</accession>
    <name>C7Q5S1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1092"/>
    <dbReference type="EnsemblBacteria" id="ACU70018">
        <property type="protein sequence ID" value="ACU70018"/>
        <property type="gene ID" value="Caci_1092"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1092"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_3_1_11"/>
    <dbReference type="OMA" id="AMKLMIP"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="122"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21037" checksum="00ADDE9FBAD33B71" modified="2009-10-13" version="1">MTTEVRDESAKNGVVRRHSAGMMRPAAVTAVGAELADLEAMCHHIADLARTRTEAPSRIRVEHLGTALEIEWPSPVAKVVSAVGAGPYRGPDSGSHGSGPGATEAAESAATHTDPPVADDGLQRVCAPMIGTFYHSPEPGAPPFVAVGDTVVPGQQIGILEVMKMMSPVEAHIAGIVREILVPDGGSVEFQQPLLAVESVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Z4</accession>
    <name>C7Q5Z4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1165"/>
    <dbReference type="EnsemblBacteria" id="ACU70091">
        <property type="protein sequence ID" value="ACU70091"/>
        <property type="gene ID" value="Caci_1165"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1165"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023778_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="12"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="693"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="713" mass="69992" checksum="66B328D2E8F7CE0D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q603</accession>
    <name>C7Q603_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1175"/>
    <dbReference type="EnsemblBacteria" id="ACU70100">
        <property type="protein sequence ID" value="ACU70100"/>
        <property type="gene ID" value="Caci_1175"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1175"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054754_1_0_11"/>
    <dbReference type="OMA" id="AWRGMPV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="39456" checksum="8E68A94217B79F25" modified="2009-10-13" version="1">MPATAIDVTPHPDLTADGIVAVAAATRDAWRAIALSTEAVDRQATEETVLRLYAESLPDSAPPEIIWCRSPLEAARLVAADAERLGAPARDRVRDLTWSVGRARLAERLGPREFGRVWQAACGDLAPLISTLIARIATAVEEHADPEDIAERTALRIALTHAVHGQFDASWLPLYEASGMACGLGRMARSAGWWWPFENAVILTERPLALRLDDQDRLHHGDGPALVYADGFAVYSWRGTPLTEEFGRRLAATSPDTIRAEENAELRRIMVEHYTPERFLKESGAQPVQEDEAGKLWRIAMGDDESIVLVEVVNSSPEPDGTFNVYFLRVPPSMLTAKAGVAWTFGLTEDEYQPLRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q676</accession>
    <name>C7Q676_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787375.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72082">
        <property type="protein sequence ID" value="ACU72082"/>
        <property type="gene ID" value="Caci_3174"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3174"/>
    <dbReference type="eggNOG" id="ENOG5034BBU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617140_0_0_11"/>
    <dbReference type="OrthoDB" id="1967476at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980624" evidence="1">
        <location>
            <begin position="31"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="17009" checksum="8E6D448DD7F64D0E" modified="2009-10-13" version="1" precursor="true">MLSSPTVRRLAVAATVALGAALVPAVTAGAAAQDPIQDPLPITPNTSFIGLVNGKAADAVITVVCPGPVSSTSVGHPVSGQTAEVRSIVPPVTAPGGFTGSAGREIVAGFSPASTAAQNIVFTSYFAPAKIPTTWWVPCGGTATMTFVPLPTSPTARSYTLTVAFANIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B8</accession>
    <name>C7Q6B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CdaR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3217"/>
    <dbReference type="EnsemblBacteria" id="ACU72124">
        <property type="protein sequence ID" value="ACU72124"/>
        <property type="gene ID" value="Caci_3217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3217"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053843_0_0_11"/>
    <dbReference type="OMA" id="GSRELWC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_30" evidence="1">
        <location>
            <begin position="365"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="431" mass="46551" checksum="2448EE6404F560D1" modified="2009-10-13" version="1">MQTLRALINWTVTQTSAVDSVTDHKTTGDSAGPLRIAGRPVAADLRALAPDLSRRVLARLLEELPVYANLPGEEVAGDIAEIVQHSVRMFADAIEARRVPDETELAAQRRSAQRRAEEGVPLDAILAAYQLGIAMVWSQVSAGATPGDHADLREVLEILLEIQRRILCSVTESYLAARRTIDSEEHSGRHALMAALLSGAEPDGTVRAAPRYAVLTLRLERHPDEDAAAPGVAARRKIRRVREALDAFWDQPCLTAFRSDRGTVLMPLDDDAAVLDHEGLRALIVDAAGAAGAPLTAAVAVADVAEVPTAVARTAEIVDLVRATGRQPGLYRLADVLLDYQLSRPSAALPALAARLEPVAQKPELLTTLQTYLGVDRDRRATANALHVHPNTVDYRLRRISELTGLSAHRTEDVGELHASLVARQALGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q752</accession>
    <name>C7Q752_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="7" type="ordered locus">Caci_1215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785434.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1215"/>
    <dbReference type="EnsemblBacteria" id="ACU70140">
        <property type="protein sequence ID" value="ACU70140"/>
        <property type="gene ID" value="Caci_1215"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1215"/>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088880_0_0_11"/>
    <dbReference type="OMA" id="FRFGRIV"/>
    <dbReference type="OrthoDB" id="1937493at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="28240" checksum="F1ACC5EFA0F21F28" modified="2009-10-13" version="1">MQGASREALAAGADRLDALTSAPGADIAAVADDLSAVAVAFGKDASLRRMLTDPARQPAQRADIATALLAGKIGADAAALVAGMARSRWSAPRDLADAVADLAVRADLAVAERDGKLDDVEDELFRLSRLLDSNGELALALADGRVPADKRVALVDGLLSGKVDVTTYRLVGRLVAAPRGRSISAGLTEIGKEAAARRQRLIAYVTAAVPMTEQQRDRLAAVLKRLYGRQVHLNVDLDPAVLGGLSVRVGDEVVDGTVATRLGQAQRQLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q785</accession>
    <name>C7Q785_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785467.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1248"/>
    <dbReference type="EnsemblBacteria" id="ACU70173">
        <property type="protein sequence ID" value="ACU70173"/>
        <property type="gene ID" value="Caci_1248"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1248"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WWGERPV"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18558" checksum="39FF48CC6EF8C7E8" modified="2009-10-13" version="1">MRAEEEAEFREYVAGRWTWLVQAAALLTGDAGHAEDLAQTALVRVFASWARVRGAESMDAYTMRILINQNKNRFRKRRVVEDLTAVPPERGSGDPDLTARVDQRAGLMAALASLPKRQREVVVLRYWEDYSEAQTAQILGCSVGTVKSQSSKALAKLRAHASVLASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C5</accession>
    <name>C7Q7C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1288</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785507.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1288"/>
    <dbReference type="EnsemblBacteria" id="ACU70213">
        <property type="protein sequence ID" value="ACU70213"/>
        <property type="gene ID" value="Caci_1288"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1288"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_11"/>
    <dbReference type="OMA" id="VPTYFRM"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="125"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="35833" checksum="46B6A3145B886B54" modified="2009-10-13" version="1">MTTLPGDASTLHDDFGDEAAPDPGTPAAKAIEGRSLTQIAWSRLKKDRVAMAAGIIIAVLVLIAIFAPLLASATGNSDPNQQFMDSIDPNTAMPLGSAGGISSNHLLGLEPVIGRDVLTRVLLGSRISLLIATSASLLSLFIGIALGVIAGYFGGWIDTLISRIMDVFLAFPLLLFALALAAIVSDHAFGMSGDTLHIAMLIFIIGFFGWPYAGRIVRGQTIALRQREFVDAARVLGAKPRRIILRELMPNLVAPILVYGTLLIPANILFEAALSFLGVGIRPPTPSWGKMLNDAIEYYRVDPAYLIIPGAAIFITVMAFNLFGDGLRDAFDPKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7H9</accession>
    <name>C7Q7H9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(S)-2-hydroxy-acid oxidase</fullName>
            <ecNumber evidence="5">1.1.3.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.15" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3265"/>
    <dbReference type="EnsemblBacteria" id="ACU72172">
        <property type="protein sequence ID" value="ACU72172"/>
        <property type="gene ID" value="Caci_3265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3265"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_405290_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003973">
        <property type="term" value="F:(S)-2-hydroxy-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="4">
        <location>
            <begin position="309"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="678" mass="70265" checksum="FCB117A4928DA668" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I3</accession>
    <name>C7Q7I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787469.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3269"/>
    <dbReference type="ESTHER" id="catad-c7q7i3">
        <property type="family name" value="Hormone-sensitive_lipase_like"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72176">
        <property type="protein sequence ID" value="ACU72176"/>
        <property type="gene ID" value="Caci_3269"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3269"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_11"/>
    <dbReference type="OMA" id="RAPENRF"/>
    <dbReference type="OrthoDB" id="1361074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="79"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="34624" checksum="BF77A19F48E9257B" modified="2009-10-13" version="1">MPLDPQIQAMRDRRVQAGAPQLYTLSLAEARAADLASIQAEAHDPEPVHAVSERVVAAEGRDIPVRVYRPNAEAVLPTLLYFFGGGWTLGSLDTCDGICRALANLAGVQVVAVGYRLAPEHRFPAAVEDCHEVLRHIAAHPADFGTDAAALAVGGDSAGGNLAAVAALLARDAGLRLAGQLLVYPNTDQLAADASMRDNVDPYLFNHRSVSWYRKHYLTSDEEATNPLASPLLAPDLTALPPALIITAEHDPLRDQGEAYARRLAAAGNSVQLTRYEGMVHGFFTMTGAVDAARHAVAQAAEALRGWFALEAVSSGAPGVSGAAVMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7L3</accession>
    <name>C7Q7L3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3299</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3299"/>
    <dbReference type="EnsemblBacteria" id="ACU72206">
        <property type="protein sequence ID" value="ACU72206"/>
        <property type="gene ID" value="Caci_3299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3299"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_20_2_11"/>
    <dbReference type="OMA" id="TIIEWIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="491" mass="51562" checksum="EEDEB186357FCBD3" modified="2009-10-13" version="1">MSTMDSPSTVPAPAPAAPGPGDDRLRGGSLSLLDIASSTMANIGPAMSFYFGFGLLATTAGVASPLTIVVAGLTVALLGNTLAQFSRAHPSAGGFITFVGKTFGPTSAVTTALLITAGYIIAISSVIAISGGFLSMTLNYYFGWNVPWFLFTLVLTALAVTLIIRGIGVSTKLAGYFFAVEMLVLVVVSVATIAKHGAHLSIKPFTPSHVKGGMSGLAEGFPLAVYMFVGWENSAALAEETENPRRNVGRAVFSSIGIMSVGYVLFAYATVTGFGYDADKTGAAAVPFIDVAHGTFGVLAFFAYIAGLTSTLGSLISGTNSQTRLLFNAGRERLLPAFLGRVHPTRRTPFNAILVFVSAALLIIGGWGLLHIVGGKGTMDPVSFFAESSTMGTILILLVYLASNVALPFYYRRYQRSEFRVVRHAVLPLIGAAAIVVPLYYLAKPGQSTPYDWFPYLALGVLAVALVYAVILTRRDPGLGERVGAIVADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z1</accession>
    <name>C7Q7Z1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5299</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5299"/>
    <dbReference type="EnsemblBacteria" id="ACU74158">
        <property type="protein sequence ID" value="ACU74158"/>
        <property type="gene ID" value="Caci_5299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5299"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_5_2_11"/>
    <dbReference type="OMA" id="STARHEC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="24"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21511" checksum="E0F469E146A50019" modified="2009-10-13" version="1">MDRSPALLLKAAAAGDAEAWHRIVDDYSRLVWSVARGFRLSLADAADVSQTTWLRLVENLDRIQNPDQLAGWLATTARRESLKLLRKAQREVPDSEEAEENVSFFGDLDNDGDPEAALVAEQDRSDLWQAFATLSERCRNLLRVVAVTPLESYAAVAEALGMRVGSIGPTRSRCLEHLKRALKALSTLPETTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q810</accession>
    <name>C7Q810_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5318"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74177">
        <property type="protein sequence ID" value="ACU74177"/>
        <property type="gene ID" value="Caci_5318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5318"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_13_0_11"/>
    <dbReference type="OMA" id="TAYIHGF"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="27339" checksum="EA57A50BF5BAE0B6" modified="2009-10-13" version="1">MTNPRVLVIIPTYNEAENLPTIVARVHAANPDVHVLVADDNSPDGTGKLADELADSDERVKVLHRAGKEGLGKAYLAGFAWGIEHEYDVICEMDADGSHRPEDFPALLKALVEQNADLVLGSRYVRGGKTVGWPKHREILSKGGNTWVRLVTGMKLADATGGYRLFRRETLERIELSTVASAGYTFQVDLAWRTVRAGLKVVEVPITFVERELGASKMSTNIVAEALWRTTVWGMQYRMKRLLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q866</accession>
    <name>C7Q866_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5374</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793962.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5374"/>
    <dbReference type="EnsemblBacteria" id="ACU74233">
        <property type="protein sequence ID" value="ACU74233"/>
        <property type="gene ID" value="Caci_5374"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5374"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="PRHTVYD"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="23"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="61"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="36823" checksum="2D5C71C6EF891B64" modified="2009-10-13" version="1">MEDTVGAVEAPVSVLDDSAAPVLSVRDLYVTFRSRHGRGRARAVDGVDLDIAPGEIVALVGESGCGKSTLARALTGLVVPTAGRVLHDGAPVSYKSRALKAYRRGVQLVLQDPTGALNPRRTVYEAVAEGLQIHGKSALGAFPDEKSKVADALSRAGLRPPERFFDLHPHQLSGGQRQRVVIAGALVLDPQVLVADEPVASLDASVRGEILKLMLDLRVSTGLSALVVTHDLGLAWNIADRVAVMYLGRIVETGTVEEVLTDPQHPYTKALLSVVAESGEDPVILTGETPDSAAIPGGCRFHPRCPLVASGAAERLGVVRQCREVDPAPLPSSGRHAACHAAALSGASEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H5</accession>
    <name>C7Q8H5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanine aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Lysyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Caci_7336</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795891.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7336"/>
    <dbReference type="MEROPS" id="M01.009"/>
    <dbReference type="EnsemblBacteria" id="ACU76163">
        <property type="protein sequence ID" value="ACU76163"/>
        <property type="gene ID" value="Caci_7336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7336"/>
    <dbReference type="eggNOG" id="COG0308">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007335_1_1_11"/>
    <dbReference type="OMA" id="CAYTNTG"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012778">
        <property type="entry name" value="Pept_M1_aminopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02412">
        <property type="entry name" value="pepN_strep_liv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="15">
        <location>
            <begin position="121"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="13">
        <location>
            <begin position="237"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1_C" evidence="14">
        <location>
            <begin position="533"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU76163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="858" mass="95378" checksum="848B6610BF1E2C04" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8K8</accession>
    <name>C7Q8K8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2263 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785567.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1350"/>
    <dbReference type="EnsemblBacteria" id="ACU70273">
        <property type="protein sequence ID" value="ACU70273"/>
        <property type="gene ID" value="Caci_1350"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1350"/>
    <dbReference type="eggNOG" id="COG4295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_4_1_11"/>
    <dbReference type="OMA" id="AHRDPFY"/>
    <dbReference type="OrthoDB" id="1481953at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="DUF2263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014899">
        <property type="entry name" value="UCP014899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02452">
        <property type="entry name" value="TIGR02452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2263" evidence="2">
        <location>
            <begin position="10"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="32563" checksum="996588F80346BA74" modified="2009-10-13" version="1">MGIYKSLALQNESIIAAGYYANPRGAHVDLAADVAAACRGTRFYTPEQTQQFLADQTALSAGGVARHETAFEVTGETSTQAGQRLVRDEGASDVAILNFASARNPGGGYLGGARAQEEDLCRSSALYTTLLEAREHYDAHRANRDTRYSHRVIYSPDVPVYRDGATRLLDTPYQISYLTSPAPNAGALAKHEPSALGEIPGLLTERAGRVLAVAAQHGVQTLVLGAWGCGVFRNDPATVAQAFRGHLADGGVFEGRFARVVFAVYDTSAAKTTLAAFQEAFENLVTPQSQPQPSVAASSASRSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q904</accession>
    <name>C7Q904_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787617.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3418"/>
    <dbReference type="EnsemblBacteria" id="ACU72324">
        <property type="protein sequence ID" value="ACU72324"/>
        <property type="gene ID" value="Caci_3418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3418"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145577_0_0_11"/>
    <dbReference type="OMA" id="CHAMRLL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="111"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26239" checksum="5031C1A4FE0BA1DB" modified="2009-10-13" version="1">MSSGQTKPAKAVNPVETVAGLRALPDVRDAVVTERVGPAGGVQVLGYVAGPDPVAGTAELHRRLMGRLPQHLIPDYLFILEEIPLTPAGDYDLKVLPEPDAASGPTEDYVEPRTKLERQIADLMVEVLRVPRVGAHDVFFALGGSSAQMFRLTLRIREIFNVQLELQEVFGAPTVEGVAALLLQSLGEKVSERVLERQEKHRRVAATWLWIRKRVPPGLPCGAQPDDLAAVEVIKAQQAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9T3</accession>
    <name>C7Q9T3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795980.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76252">
        <property type="protein sequence ID" value="ACU76252"/>
        <property type="gene ID" value="Caci_7426"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7426"/>
    <dbReference type="eggNOG" id="COG5485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1640759_0_0_11"/>
    <dbReference type="OrthoDB" id="1612408at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="17392" checksum="34A00391BD813684" modified="2009-10-13" version="1">MTESPLIREFYDAFQRAEFDRWDPIADAEMVINTPLGFGVSGLQALKDFAGQLYDLAWRIDLVDEHLALDADGNGRGFISFCLNWKHTKVFLGFEPTGREGTSIETLIFTLAGGRITQIDVSENTLDLVMYEAELGWPIPDNVHPDALLTGVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9V7</accession>
    <name>C7Q9V7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796001.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7451"/>
    <dbReference type="EnsemblBacteria" id="ACU76276">
        <property type="protein sequence ID" value="ACU76276"/>
        <property type="gene ID" value="Caci_7451"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7451"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_0_11"/>
    <dbReference type="OMA" id="PGWTLKW"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="33021" checksum="7C86084F1B53F43F" modified="2009-10-13" version="1">MTAATHPSPQPASPQSSAHQGPAPQPASRRRRFRPRRRGVEAKPRFAIVVTALFFVLLYLPIAMVVLFSFNSQKSLTVFKHFSTRWYSAFFHDHVLLSSLGMSLKISLVAMIGSVVLGVALALGLVRARGRLGTYSGLIMLVPLITPEIVTGVASLMLYKGLNITLSTGTVMISEITFSISYVTVILRSRVAALNPEVEEAAMDLGATRWQALRLVTLPALLPAILASAVLIFALVFDDFVLAYFTTGVDPQPLAVRIYSAIRFGVEPTINAVGTLMLAGSITLIAVALSIPRLFGRSGGLDLLSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA21</accession>
    <name>C7QA21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785713.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1496"/>
    <dbReference type="EnsemblBacteria" id="ACU70419">
        <property type="protein sequence ID" value="ACU70419"/>
        <property type="gene ID" value="Caci_1496"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1496"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_2_11"/>
    <dbReference type="OMA" id="CIHRART"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22384" checksum="211765EF0B665777" modified="2009-10-13" version="1">MTDAPRRKRVPRAEREQQILAAAEEVFAERGFQNTSMDEVSLRVGVSKPMLYEYFSSKEGLLLACVARIRADLHSVTLNAVSAAEPDGPRAVLEAGLEAYFDFADRHGRAWAVLLNESVIAAGPAEEAIEAIRGQQTRLLEDVLGHWLPAASPARVSILAHALVGAGERVARWRLRDGSGIGPRESAVLLADAFWPGFAEMSANKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA98</accession>
    <name>C7QA98_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70496">
        <property type="protein sequence ID" value="ACU70496"/>
        <property type="gene ID" value="Caci_1575"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1575"/>
    <dbReference type="HOGENOM" id="CLU_1892407_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045443">
        <property type="entry name" value="DUF6504"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20114">
        <property type="entry name" value="DUF6504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14955" checksum="B8088A322B6550C3" modified="2009-10-13" version="1">MSANGTGAAVSTDDELIDVLRRHGEPAHFIWRGKLYRVRQVLSHWIQVGADSGELPSVLLRTDLRLGTVETLVFGRDREVERELWSVRASVGRDGDVEVFQLCHDVPTGGWLLVAESLSSLPEHLGRVLKFPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW1</accession>
    <name>C7QAW1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794163.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5575"/>
    <dbReference type="EnsemblBacteria" id="ACU74434">
        <property type="protein sequence ID" value="ACU74434"/>
        <property type="gene ID" value="Caci_5575"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5575"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="NTFHEVG"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="481" mass="47854" checksum="2940644DBD7D693E" modified="2009-10-13" version="1">MEQDTDLEQEATGVEHTEAGGRWTALTLLCLAQFMLIVDITAVNLALPSMAQDLDLGRQSLTWVPAAYTLCFGGLLLLGGRLADGLGRRRAFLIGLAAFTGASLLSGAAHTGSELIAGRAAQGVAAALLSPAALSIVTTTFHGPERTKALGVWGAIGGAGAAVGVLVGGALTSGPGWRWVFFVNLPVGLAVLALLPRLVPASAPARSLRGVDVPGALTATATAALLVYGLIHAGSSGWGTAATMLPLAGAVLAAGALVLVERSAPQPLLRPGLVRNRAVVAGTAVMFAATILLLTGFFLVSWYLQHRAGYSALKTGVVYLPVAVATGLGAHLASRSLGHLGFRPTAVSGFVVAAVGALLLTRLPASGNAALAVLPGFLLLSAGVGMALVTATTVALHEADHTEAGLISGLVNTGHELGSALGVALASVLAAGSLGVTATGVGGFRTAFAVAAGIAAVAGVTALGLLPAGRPDPTARPAFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBF9</accession>
    <name>C7QBF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785830.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1615"/>
    <dbReference type="EnsemblBacteria" id="ACU70536">
        <property type="protein sequence ID" value="ACU70536"/>
        <property type="gene ID" value="Caci_1615"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1615"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="TDTCEVT"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="304"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="42609" checksum="7755D6B2BA69BE83" modified="2009-10-13" version="1">MSEARPLMTRVTPARVVACVWVLSTLSLFIAQALRLKRPWGGTVVGRDPSSDPLMTDHRQLVVLIAAAGLVALGCRLLGRRPVSAVAAVAALMASVFAVNYDLHTSAIAPDQYVAVCVAVFFVAAGGGRRVGIWCAALAFAGVVGYVAASLVLGLRVDTSIEVVVLLITVLAWVLGDARRAEREHAEQLRAQVAGRAVTAERLRIARDLHDMVAHEIGVVALQAGAARLVVLRRPDAAEQALGIIEDTSRTTLAGLRRMVATLHDAPADPVGLEGIGRLVANARAAGVRVDVQWRGRRLPLPPEVDSSVFRVIQESVTNVIKHSGTKQCRVSVGFEDGAVSVVVVDSGAGSDAGGVGSTGYGLPGMRARIEILHGEFSAGPRPEGGFRVAARVPVSAPVSASVSVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH9</accession>
    <name>C7QBH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1635"/>
    <dbReference type="EnsemblBacteria" id="ACU70556">
        <property type="protein sequence ID" value="ACU70556"/>
        <property type="gene ID" value="Caci_1635"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1635"/>
    <dbReference type="HOGENOM" id="CLU_184570_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="70" mass="7373" checksum="ABBB1F863477335B" modified="2009-10-13" version="1">MDTAGLPPVGALVRDAGGRIGRLMAYTRARAWLRPPGGGREWDVEPGTITEVPGWDTVAGAGREGTAQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBV0</accession>
    <name>C7QBV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792298.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3667"/>
    <dbReference type="EnsemblBacteria" id="ACU72569">
        <property type="protein sequence ID" value="ACU72569"/>
        <property type="gene ID" value="Caci_3667"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3667"/>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_9_1_11"/>
    <dbReference type="OMA" id="SPYMYLA"/>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="229"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="497" mass="54221" checksum="6A583D28274884E9" modified="2009-10-13" version="1">MLSPSIPVRVTVTELPGGNPLQTYEELLRDRPGHDVFLFESPAGPVQDRRWAAVGWDRLAEIRLYAGRVELTAGAALGDLLAETVSAEAGPPKEAYDGIRVWDASAPETRWRLLAAITEAFDVDTDLGQDTFAFGFLTVLSYEAAWDIEDIPQTQQDADMPRCTLALFRNTVWYDQHSGGVRLLSASGPHFPAAGSEQALTPAAASGESEPSIIPAAPAPRSVTDNVEQETFTGRVERCLRHIGVGDSYQIQIGHRIDVETDLTPVEVYKRLRHRNPSPYMYLTPWSGRTVIGASPELFFRIEGRRILMRPIAGTAPRAADPAEDERRVAELRASAKEQAEHVMLVDLCRNDIGRVCVPGTLQVETMMEVEPFAYVHHLVSTVSGDLEDGVGVWEAVRATFPAGTMTGAPKVRAMEIINEIEDDPRGAYAGALGLIDVRGFAVLALCIRTTVHDGRAYSTQASAGVVADSVPASEWRETLAKMSATYWALTGEELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBX7</accession>
    <name>C7QBX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3694"/>
    <dbReference type="TCDB" id="3.A.1.105.27">
        <property type="family name" value="the atp-binding cassette (abc) superfamily"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72596">
        <property type="protein sequence ID" value="ACU72596"/>
        <property type="gene ID" value="Caci_3694"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3694"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_368308_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="461"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="421"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="493"/>
            <end position="500"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="756" mass="80168" checksum="D7D1241B5FAA432A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBZ3</accession>
    <name>C7QBZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3710"/>
    <dbReference type="EnsemblBacteria" id="ACU72612">
        <property type="protein sequence ID" value="ACU72612"/>
        <property type="gene ID" value="Caci_3710"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3710"/>
    <dbReference type="eggNOG" id="COG2138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074823_0_0_11"/>
    <dbReference type="OMA" id="HGYGSHR"/>
    <dbReference type="OrthoDB" id="1573073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="28507" checksum="BA18B14116764B58" modified="2009-10-13" version="1">MADNSAPVTKTSLRAARAAVVIVGGHEGGGRVAVDPLVEYGPLLCAASAGRQLDESLYQALDSSDLPVCVVPMTLGRDPQLVAGIARTLTVLSRGAAAGRVVLAESFGTAALLTGWLRVAVAGAARRHGGTDLAMLVTANAANRFDDAELFRIARLVKVQEGLPWVEVAFRGGDPDLAEGIDRCGRLGARRVAVVPADFGAGTDAPMSGVTDTPMPSVIDGGPLLSPSAISGMLATRVAGALLKLTRGDDGIAAGLDADHGHGHGGEPWRAKKKIWGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC14</accession>
    <name>C7QC14_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lanthionine synthetase C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3731"/>
    <dbReference type="EnsemblBacteria" id="ACU72633">
        <property type="protein sequence ID" value="ACU72633"/>
        <property type="gene ID" value="Caci_3731"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3731"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009398_0_0_11"/>
    <dbReference type="OMA" id="HENLIAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="150"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1012" mass="105995" checksum="B1F8097975C33EBF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCD4</accession>
    <name>C7QCD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794311.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5724"/>
    <dbReference type="EnsemblBacteria" id="ACU74582">
        <property type="protein sequence ID" value="ACU74582"/>
        <property type="gene ID" value="Caci_5724"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5724"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_5_1_11"/>
    <dbReference type="OMA" id="RMYLTHA"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="14069" checksum="D05C17CDD9BE84E3" modified="2009-10-13" version="1">MSSIQRIGSDGQWENEYGYSRLVVAGPHAWVAGCTATVDGQVQGNGDPYAQMKVSLEIARKALEQAGFGLHDVVRTRWYVVHARDIAEVGRAHGEVFAEGRPAATALVVSGLIDPGMLVEVELDAYRGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCE7</accession>
    <name>C7QCE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, TraR/DksA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5737"/>
    <dbReference type="EnsemblBacteria" id="ACU74595">
        <property type="protein sequence ID" value="ACU74595"/>
        <property type="gene ID" value="Caci_5737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5737"/>
    <dbReference type="eggNOG" id="COG1734">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043144_0_1_11"/>
    <dbReference type="OMA" id="RATLCMT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982739" evidence="6">
        <location>
            <begin position="42"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="201"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="275" mass="28399" checksum="C65484C9B3067D97" modified="2009-10-13" version="1">MTAVTTSRTKASEAATGATHAAKGAAGPAAAGKAVPTPARAATGAKAAPPNRRSGAGEARRSASGPAASVSGQVSARSAAATPAVTKTAATKPAETKPAETKPAETKSTARTPAKHQHPAHETAAAEKETPMTVTQISQTMAGVGGLPPYRTGEDPWTPEEVGELQAELEGDAARLRREISTAETGIADLLRDSGEGAGDDQADAGTKNFEREHEMAIANNAREMLQQTERALARLAADTYGVCESCGEPVGKYRLQAFPRATLCMSCKQKQERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS8</accession>
    <name>C7QCS8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine--fructose-6-phosphate transaminase (Isomerizing)</fullName>
            <ecNumber evidence="3">2.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7717"/>
    <dbReference type="EnsemblBacteria" id="ACU76541">
        <property type="protein sequence ID" value="ACU76541"/>
        <property type="gene ID" value="Caci_7717"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7717"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_2_1_11"/>
    <dbReference type="OMA" id="QSFYVMA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="35"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="199"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="348" mass="36522" checksum="2B85F75C8BA59F80" modified="2009-10-13" version="1">MSDAKPGEIMAREIAEQPAVLERILTEGLPRIREAAERVKAAQPRFALLTARGTSDNAAYYAKYLMEIALGLPVGLTSMSTTTAYHAEPDLRDVLCLTVSQSGGSPDLVAHTEMAKARGGLTLAVTNVAGSPVNQASELSLDVLAGPELALPATKTYTAELLTLWLLVDALRGGDGSAAKALPELAAGVLARESEVVDLAQRYRFASRLVLTARGYSYPTVREAALKIMETSYLPAHAFSGADLLHGPLAMVDNVSPVVAVAAEGAGGTALEPVLERLHERGADLVVVGSAEHVAGATAGFVLPSGIPEELSPILEILPLQQLAYHVTMSRGLNPDAPRALAKVTQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDU1</accession>
    <name>C7QDU1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794444.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5857"/>
    <dbReference type="EnsemblBacteria" id="ACU74715">
        <property type="protein sequence ID" value="ACU74715"/>
        <property type="gene ID" value="Caci_5857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5857"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="CTGIVCG"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="36352" checksum="67071C940DA2D8EC" modified="2009-10-13" version="1">MSSRLDDIARQAGVSKATVSRVLNERPGVSPQLRKAVLTALDVLGYERPSRLRPRSAGLVGLLLPELESPIYPLCAQVIETNLSRQGFTPVLCSQTPEGAGEDEYVGMLLDRGVSGVIFVSGLHADSGQDHSRYRDLVAQRLPLVFVNGFIPNLEAPFISCDDRAAGELAVAHLAELGHRKIGLLLSSDRHIPARRQLSGYRTAMETGFGAGGYDPDLVDISFPGVEGGYAGASRLLQRNVTAIVCGSDMMALGAIRALKQHHKRVPEDVSVIGYDDSVLMGYTDPPLTTVRQPVLSMGVAAARTLIDQIRGVTIRKTESLFFPELVVRASTGPLAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDV6</accession>
    <name>C7QDV6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7720"/>
    <dbReference type="EnsemblBacteria" id="ACU76544">
        <property type="protein sequence ID" value="ACU76544"/>
        <property type="gene ID" value="Caci_7720"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7720"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="TLSVIWD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="70"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="33837" checksum="6DE20A13156A416C" modified="2009-10-13" version="1">MRGKALPYVFLVPSVVVLGTMMGYPLVRMVMLAFQNMNNYRKFVNPSLVSYVGFDTFSSILHDPLFWQVIRRTLIWTALNVALSMLIAMAIAALLGRISSWARVILITVLLFVWSMPTIVTGTVFRWLFDNAYGVIDYILYLCGGKGMLHHDWFADPNQGLYVVVTSVVVWGALPFLVLALHAGMTQVPTELKEAARVDGASPLQVYRNVTLPILRPLLMITTALSFIWDFQVFNQIWTMRNGAPEQGYWTIGVYLFEQAFDRNRYSDGAVISVAMIVVMMLVLVFYIRQMLRIGDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE13</accession>
    <name>C7QE13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7777</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7777"/>
    <dbReference type="EnsemblBacteria" id="ACU76601">
        <property type="protein sequence ID" value="ACU76601"/>
        <property type="gene ID" value="Caci_7777"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7777"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_3_11"/>
    <dbReference type="OMA" id="TRPWLFW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="144"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="37122" checksum="4D2AA45A5B83B73D" modified="2009-10-13" version="1">MADDIPPRDVNDEPGESDLPGTPGGRGAEFLGEQGQQPGLMIDAVTPGGEDILQSGTEPADTEFTIAARNQWQLVLRRFRQHKLAVASAVVLLLVILFATLGPAIWKYGPNDFSNDFSVAPSLSHPFGTDSNGADHMAQVMAGTQLSLKIAFTVAIAGTVFGSIYGAISGFYRGATDTLMMRLVDLVLTIPALAVGALLGKKFGNNWVLLAVVLAGLLWTGSARVVRGQVLSVREKEYIEAARALGATDRRIIFRHILPNVAGPIIVLFTLLVAAAVLTETALSYLGFGVQFPDISLGSLITSGETAATGGRGWLFYFPGLFIILIALTVNFIGDGLRDALDPTQTKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE46</accession>
    <name>C7QE46_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7810</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7810"/>
    <dbReference type="EnsemblBacteria" id="ACU76634">
        <property type="protein sequence ID" value="ACU76634"/>
        <property type="gene ID" value="Caci_7810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7810"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="NVGHEEK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="38"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="27280" checksum="69486B0C6AD44D2D" modified="2009-10-13" version="1" precursor="true">MTATAAESAGTSGPVEPASVSASVSESGSASGPAGPIVRLDAIRKDFGDTAALDGVTLHIRQGEAVAVMGPSGCGKSTLLNLVAGLDRPSSGRVVVHGEDLGALSETGLALFRRRRIGMIFQFFNLIDDLPALDNVALTAQLAGVPAGQARRRALELLGELGIADRKNAYPQQLSGGERQRVAVARALMNRPALLLADEPTGALDSRSGEQVMDLLIDLNQLGQTLLMVTHDQRLATRCASRLVEVADGRIVAERALERTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER8</accession>
    <name>C7QER8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3957"/>
    <dbReference type="EnsemblBacteria" id="ACU72838">
        <property type="protein sequence ID" value="ACU72838"/>
        <property type="gene ID" value="Caci_3957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3957"/>
    <dbReference type="eggNOG" id="COG3655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_31_8_11"/>
    <dbReference type="OMA" id="CRYLDCQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="94" mass="9901" checksum="680DD637C58B6423" modified="2009-10-13" version="1">MPIVVDIDVMLAKRKMSVGELADRVGITPANLAVLKNGRAKAVRFTTLAALCEALTCQPGDLLRWEADDARGDEPGSLTPANNTRGAVDQGVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFX9</accession>
    <name>C7QFX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786249.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2036"/>
    <dbReference type="EnsemblBacteria" id="ACU70956">
        <property type="protein sequence ID" value="ACU70956"/>
        <property type="gene ID" value="Caci_2036"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2036"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_11"/>
    <dbReference type="OMA" id="ATAYHTD"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="24031" checksum="083DE5AE1BE6647A" modified="2009-10-13" version="1">MAIERRPLREQIKDVLLERLGRGEYAPDQPINEVHLAADLGVSRTPLREALIGLEREGIIISERGKGFRFAPMSPQEFRDLTTIIATLESLALELSPPEYLKHIGPQLLEEAHAFSAPKAELGVIERYDDEWHDRLLSGCRNDRLMDLITTLKLTMHRYERVVVGDQQVLERSAVEHEKIAECLVAEDLPGAVAALKANWESGMHRILEKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGB2</accession>
    <name>C7QGB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792686.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4092"/>
    <dbReference type="EnsemblBacteria" id="ACU72957">
        <property type="protein sequence ID" value="ACU72957"/>
        <property type="gene ID" value="Caci_4092"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4092"/>
    <dbReference type="HOGENOM" id="CLU_2341620_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="10409" checksum="5A9033E97358332A" modified="2009-10-13" version="1">MAFDTDAYIRDLAAVHGLAPKAGDTDRADLTSRAVRAELEDIKTRTQALHDWSAAVVADHDAAKPHTAETAAVGAAARRSRPARRRAAARPSARPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGI4</accession>
    <name>C7QGI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794593.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6007"/>
    <dbReference type="EnsemblBacteria" id="ACU74864">
        <property type="protein sequence ID" value="ACU74864"/>
        <property type="gene ID" value="Caci_6007"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6007"/>
    <dbReference type="eggNOG" id="ENOG5032XUD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1944846_0_0_11"/>
    <dbReference type="OrthoDB" id="1344414at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="13740" checksum="309692A7ECE71464" modified="2009-10-13" version="1">MATGLSRIQIEIGASAHWGVEAAVRPVIDGRDMIRESFVSGPGLPPEVLLRPNGELRAAPEPREVVLAEADCAPECCGALAVTIRLDGEHVVWAGWRDLNGPAPVLPEFRFDAGEYDAEIARAELAADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK8</accession>
    <name>C7QGK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalamin (Vitamin B12) biosynthesis CbiX protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794617.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6031"/>
    <dbReference type="EnsemblBacteria" id="ACU74888">
        <property type="protein sequence ID" value="ACU74888"/>
        <property type="gene ID" value="Caci_6031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6031"/>
    <dbReference type="eggNOG" id="COG2138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056929_0_0_11"/>
    <dbReference type="OMA" id="SAGHAKG"/>
    <dbReference type="OrthoDB" id="1573073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="30926" checksum="F9FEA6B9DAF8BB38" modified="2009-10-13" version="1">MTALLIVGHGTRDAEGAQDFRAFVERVARRAPQAVEAVDGGFIELSAPPVSEAVARLVGAGHHRVAAVPLVLVAAGHAKGDIPGSLNRERLRHPGLSFSYGRPLGVHPTILSLLEARLDTVLPREERADAAVLLVGRGSTDPDANAEVYRAARLLWEGRGIGMVETAFVSLAQPSVSEGLERCRRLGAKRIVVLPYFLFRGVLPDRIVEQSAGYDVAPVIGDCDELADLVLERHAEAVAGDIRMNCDTCVYRIAMPGFEDKVGAAQAPHHHPDEDGHSHHHSHAHSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH78</accession>
    <name>C7QH78_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784312.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0062"/>
    <dbReference type="EnsemblBacteria" id="ACU69017">
        <property type="protein sequence ID" value="ACU69017"/>
        <property type="gene ID" value="Caci_0062"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0062"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134463_1_0_11"/>
    <dbReference type="OMA" id="SRDFMPV"/>
    <dbReference type="OrthoDB" id="1924578at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="14"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="13886" checksum="25A05420B0DF21B2" modified="2009-10-13" version="1">MSALPKVGEALPELIIPITPTRIVSGAIASRDYQDVHHDVPAAREKGSPDIFMNILTTNGLVGRYVTDWAGAEARILKIAIRLGVPNYPGDTMTLTGSVASVGEDGAVEVAIRGANQLGNHVTGTVTLKGLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHB2</accession>
    <name>C7QHB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784346.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0096"/>
    <dbReference type="EnsemblBacteria" id="ACU69051">
        <property type="protein sequence ID" value="ACU69051"/>
        <property type="gene ID" value="Caci_0096"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0096"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="YKHMVGH"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="270"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="388" mass="40682" checksum="0437393671746424" modified="2009-10-13" version="1">MEAIVVGAGFGGLTAAVGLFQRGWDVTVVERATELRPVGSGLAVAPNGLRALDTLGVGDAVRKLAAFQGDATVTRPDGRVIARTASKAIVRRFGDAVIPATRSSVMDVLTALVPADVFRLGVAAQGVEAGSASQRPCLLTDSGRLEADMIVAADGVNSVLRRALFPEHPGAVYSGITAWRLLVPTPAGDFLPGEVWGGGRVFGITPLADGRTYAYGADHAEPGITYPDEKAELLRRFGDWHFPIPALISGADPETVLHNDIYEIAEALPAYHRGSVAILGDAAHAMTPHLGQGANQAMEDGVTLAALVGPAKDSEEIASALARYTALRALRGADMVRRSHRMGALTQSTSRSKTALRNLGMSLVGRLVPDLALRAMEPVVAWRPPEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB2</accession>
    <name>C7QIB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6135"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74989">
        <property type="protein sequence ID" value="ACU74989"/>
        <property type="gene ID" value="Caci_6135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6135"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_4_11"/>
    <dbReference type="OMA" id="FYYCSGG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983161" evidence="1">
        <location>
            <begin position="31"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="57"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="455" mass="47959" checksum="8EF1B7B08D845223" modified="2009-10-13" version="1" precursor="true">MARPSQHHRNRRVGLAAAAVLSLAIVPVAAASPALATPGSAAASAAASASSASSNGKVSVGYFTQWGIYSGFYEKNLIASGAVKKLTEIDYAFSNIAPDGTCASADAWADWQKPVDAANSVDGTADTGAQSIAGNFNQLRELKKAYPNLKIVMAIGGWSESTNFSAAAATPASRAKFAQSCIDMYIKGNLPGVAPGAAAGIFDGISIDWEYPDGVGDNNPHGPQDTHNFTLLLQELRNQLDTAGRPDGKHYLLTADMPAGPENVSHIEIGAVSRILDWMNVMTFDFHGTWETTGPTNFQSNLFPSPFDPAPRATSSNPFPVNGEISTLQVVMNYLQHGATPNKIALSIPLYAHGWTGVAPGPRGDGLYQPATGVATDVVYNQVAAQPGTVHHDPITGAVYKYDPASKTFWTYDDPQSIQEKVLFIKALGLRGDMAWSMDGDTADGALVNAFGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL0</accession>
    <name>C7QIL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794816.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6233"/>
    <dbReference type="EnsemblBacteria" id="ACU75087">
        <property type="protein sequence ID" value="ACU75087"/>
        <property type="gene ID" value="Caci_6233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6233"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_0_0_11"/>
    <dbReference type="OMA" id="RVQEETF"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17111" checksum="2255693DA2CE66D0" modified="2009-10-13" version="1">MNSVSIVGPGDREPIDLGPARITVLEDGSTTGRRLGVAEIRLAARSAGPPQHRHAEHDEGFYVVSGTAVFTVGATDYEAPPGTLVMVPPGAPHTFANPGDEPLVMINTFTPDLYVHYFGDVRDAMARGASMPEAAAEVMPRYATTPATDFAQPPTSPPADAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ08</accession>
    <name>C7QJ08_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ordered locus">Caci_0195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784445.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0195"/>
    <dbReference type="EnsemblBacteria" id="ACU69150">
        <property type="protein sequence ID" value="ACU69150"/>
        <property type="gene ID" value="Caci_0195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0195"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086034_4_2_11"/>
    <dbReference type="OMA" id="WHIIVIL"/>
    <dbReference type="OrthoDB" id="1907955at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="9397" checksum="91093682CB91B6AC" modified="2009-10-13" version="1">MGDLQPWHIIVILVVVFLLFGAKKMPDMARSVGQSLRIFKSEMRQSQKETEEVAKQANDSVRVTPAVENSGSVPASDAAEKHTSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ26</accession>
    <name>C7QJ26_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784463.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0213"/>
    <dbReference type="EnsemblBacteria" id="ACU69168">
        <property type="protein sequence ID" value="ACU69168"/>
        <property type="gene ID" value="Caci_0213"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0213"/>
    <dbReference type="HOGENOM" id="CLU_1238360_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23146" checksum="9B83EE30A8F45F7E" modified="2009-10-13" version="1">MPKIDWTPGQGKRGRPLRRVLGMGQQQGLLVMYGLAAIAVVLALAAACGAFDGSGPQPSAQTAGESTNPDDPAGAPSIPKDSTKSTQILLGSVQHYADLLASGQKIVGTTHYPDMAAYAQAFADASSPAARFSKFRTSPNPESDTTYLNAERQAAAAYGGDHGSRLDAWLRDMAKVKSDLGDWVATAAQYQQGAANQAVLDAAASTVNQDLATARDAANSLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ66</accession>
    <name>C7QJ66_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784503.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0255"/>
    <dbReference type="EnsemblBacteria" id="ACU69208">
        <property type="protein sequence ID" value="ACU69208"/>
        <property type="gene ID" value="Caci_0255"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0255"/>
    <dbReference type="HOGENOM" id="CLU_1841510_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="15083" checksum="5F9BB96D00A67C93" modified="2009-10-13" version="1">MAARGWNRQYITQVHIEEPLAGTCGNSLGPETDQNDVWDARYPSTNGRDYADQQVHTYVSAAYAASRVAASDPKCSGVTARTAGGFAWHGTAREGIQHVLFVRLNNKVSTLVITVDGHDYDSALDTALLQTMAQRLANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJC1</accession>
    <name>C7QJC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784558.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0310"/>
    <dbReference type="EnsemblBacteria" id="ACU69263">
        <property type="protein sequence ID" value="ACU69263"/>
        <property type="gene ID" value="Caci_0310"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0310"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_5_0_11"/>
    <dbReference type="OMA" id="RTFVTVH"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="30383" checksum="75F3B16AAA37CD8B" modified="2009-10-13" version="1">MDLALLRTFLAVHRAGSLTRAAADLGVSQPAVTAQVRTLEQRVGRELFVRLPRGVAPTAAADELARAIAPHLDALAAVAHETLVPDSGPLAAVRLGCPASLTTTLLLPALAPLVDEGLRVVVAGGRSDDLVAQLATGRLDLTLAVTRPRLPGVTVIPLADEEYALVGAPRWKPFDRTGRTPLLDLSENLPYISLYWSSVYDTRPTSDAALVIPDLRGVLDAAVAGCGAAVLPLPLCAPALDDWTLVLLDEPEIPPIRTLFVAVRGQRARSAAVARVRDRLVAVASRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJP6</accession>
    <name>C7QJP6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein Caci_2351</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786562.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2351"/>
    <dbReference type="EnsemblBacteria" id="ACU71269">
        <property type="protein sequence ID" value="ACU71269"/>
        <property type="gene ID" value="Caci_2351"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2351"/>
    <dbReference type="eggNOG" id="COG0217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062974_2_2_11"/>
    <dbReference type="OMA" id="ETIMYEG"/>
    <dbReference type="OrthoDB" id="1304328at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="26919" checksum="BDDC5A0B5AE95FD6" modified="2009-10-13" version="1">MSGHSKWATTKHKKAVIDAKRGKLFARLIKNIEVAAKTGGGDVTGNPTLFDAVQKAKKNSVPADNIDRAVKRGSGAEAGGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGSMADPGSVSYMFTRKGVVLVPKTGSLTEDDILMAVLEAGAEEVNDLGESFEVVSEAADLIPVRTALQSAEIDYESAESSFLPSVQVELDEDGARKVFRLIEALEDSDDVQNVYANFDVSDEVMEKIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU6</accession>
    <name>C7QJU6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792913.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4320"/>
    <dbReference type="EnsemblBacteria" id="ACU73184">
        <property type="protein sequence ID" value="ACU73184"/>
        <property type="gene ID" value="Caci_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4320"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_1_11"/>
    <dbReference type="OMA" id="WEDQAAT"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981734" evidence="1">
        <location>
            <begin position="30"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="43484" checksum="610009BB852C5FF9" modified="2009-10-13" version="1" precursor="true">MKTHVKVAAAAVAAAGLLTAAGCGSSSPAGSGSVSGSGGGVVKLSVLTGFTGPDGPSYQALVSQFNASHPTIKVTMDIQPWDAIGQKLPAEWATGQGPDLATPNFDPGVIFNYIKTNSVLPLDSSVGAADSQINASAFPPAVTKAFTVNGHLYAVPANLATVALYYNKTMFTAAGITDPPKTSEEFVADVKKLTLGGASPTQYGISLADHQTIEMWPILQWMNGGDIVGPDGCATIDSAASVQALSTWAGMVQNQHVSPVGQTGADADTLFSAKKAAMELNGPWAADGFRKAGIDLGIAPVPAGSSGPVTLASTVPMMVAKNTKHKEQALEFLSWWTGKTAQASFSKGSGYPPARSDVTVSDPNVAVFAQGLPTARLYLAGLPTSSQIDTDIYTPLLGQLTRGADAQKSADAAAKSINQLTGCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJZ0</accession>
    <name>C7QJZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein/LacI transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4364"/>
    <dbReference type="EnsemblBacteria" id="ACU73228">
        <property type="protein sequence ID" value="ACU73228"/>
        <property type="gene ID" value="Caci_4364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4364"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_2_11"/>
    <dbReference type="OMA" id="ISDIQDM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983201" evidence="1">
        <location>
            <begin position="33"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="91"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="37873" checksum="9ACF301134A4DFC5" modified="2009-10-13" version="1" precursor="true">MRPMRPRVRTLTRPAIAAAVAAACLAGTAACAKSAPKAAASGATSTGTAAQQVVATSASGPGCTSQTYGGGVAQLNLTDPSTIVGFSQSESTSNPFRSTETDSITNQAKSLGVKLIQRNANADVNAQNSQIEDMIAQGAKVLIVAPENSDGLGPALAEAKAKKIPVLTIDRTVTGTACSDFIAFIGSNFYGQAQIAADDLATATGSQAKVAILSGTPGNNVTTDRTNGFQDQVKAKYPNMTVVASQTGKFDQTDGQSVMAQMLQANPGITAVYAENDEMALGAIQAITAAGKKPGKDIKIVSIDGTQQAVQDVAAGTIYADVETNPRFGPLAFSSLQAFFGTSGVASKVIIKDSHFTQANAQQALSGGQVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK18</accession>
    <name>C7QK18_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate_J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4392"/>
    <dbReference type="EnsemblBacteria" id="ACU73256">
        <property type="protein sequence ID" value="ACU73256"/>
        <property type="gene ID" value="Caci_4392"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4392"/>
    <dbReference type="eggNOG" id="COG3299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024495_0_0_11"/>
    <dbReference type="OMA" id="QPPLVWE"/>
    <dbReference type="OrthoDB" id="195888at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011749">
        <property type="entry name" value="CHP02243"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02243">
        <property type="entry name" value="TIGR02243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="388"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="656" mass="70691" checksum="DCD20F1790F0B062" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK91</accession>
    <name>C7QK91_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6311"/>
    <dbReference type="EnsemblBacteria" id="ACU75165">
        <property type="protein sequence ID" value="ACU75165"/>
        <property type="gene ID" value="Caci_6311"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6311"/>
    <dbReference type="HOGENOM" id="CLU_2449188_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="14"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="9638" checksum="AD75FD330A4F5C24" modified="2009-10-13" version="1">MQKSLEARLTTLSRLRIMIRDVLRLPESEEIDHRTLRALGAVSVQVIALQFSILKATSVDVAMSELVGGASVAEIAELIDARRPGAGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK8</accession>
    <name>C7QKK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796832.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8284"/>
    <dbReference type="EnsemblBacteria" id="ACU77107">
        <property type="protein sequence ID" value="ACU77107"/>
        <property type="gene ID" value="Caci_8284"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8284"/>
    <dbReference type="eggNOG" id="COG3222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075662_0_0_11"/>
    <dbReference type="OMA" id="CDAWFGP"/>
    <dbReference type="OrthoDB" id="1445278at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="22441" checksum="318BE47725288046" modified="2009-10-13" version="1">MSTLIVIAKAPVPGRVKTRLTPPFTPEQGAALAGAALADTLEAVATARFPLSVLALEGDSALVAVPAGFAVVPQVGGGLDRRLAAAFREAAILDPGPALLIGMDTPQVTGPLLEACMPTAWEDATIGLAEDGGFWSLGFSRPREVDLDGLLLGVPMSTDTTGAVQLARLTDAGLRVRMLPVLRDVDTVADLPAVAAAAAPVSRFAAVAHAVGVAGTTLPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVK0</accession>
    <name>C7PVK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784651.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0404"/>
    <dbReference type="EnsemblBacteria" id="ACU69356">
        <property type="protein sequence ID" value="ACU69356"/>
        <property type="gene ID" value="Caci_0404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0404"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_17_2_11"/>
    <dbReference type="OMA" id="GYSCQVK"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="24198" checksum="5AF13316E11CF698" modified="2009-10-13" version="1">MPTAVVIGVGPGLGMSIARRFGGAGHSVALVSRSDARHADYLAELASAGIESEAFVADVNDREQVGSVVDAIEAKHGIDVLYYGPGASDVSQPAPITETTADEVRASMGVVYAAVDIVGRVLPGMMARGRGGLLFAGGLSAVVPVPSLGALAVTSAALRNYALTLNAGLADTGVYAGTLIIGGLIERGDIHGFVVAHPEMFGHVPLRTLNPDDIAAAAWEMYAARDRAEETFSVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM2</accession>
    <name>C7PVM2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784673.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0426"/>
    <dbReference type="EnsemblBacteria" id="ACU69378">
        <property type="protein sequence ID" value="ACU69378"/>
        <property type="gene ID" value="Caci_0426"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0426"/>
    <dbReference type="eggNOG" id="COG3871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1516219_0_0_11"/>
    <dbReference type="OMA" id="WHFGTAR"/>
    <dbReference type="OrthoDB" id="1701945at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="43"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="18767" checksum="CC558688F1706CBC" modified="2009-10-13" version="1">MLETPEELAALQTLLDDSAAAAGPHMRGIFTDDRRLNAAELSARLQGMCLIAVATVTADGRPLTGPFDGYFLHGSWWFSSAPDSVRIRHLQARPGVSATYLPGEELSVTAHGRAELFDLHAPECDDLRQAMLDFYLPKQGPAFQEWMDGLEGGIGVRIDARKLFTFFASSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVN3</accession>
    <name>C7PVN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784684.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0437"/>
    <dbReference type="EnsemblBacteria" id="ACU69389">
        <property type="protein sequence ID" value="ACU69389"/>
        <property type="gene ID" value="Caci_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0437"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051820_2_0_11"/>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="74"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="36279" checksum="DA7C1252D356DF07" modified="2009-10-13" version="1">MKDWWIFKGEGVPHRRVEQLPPPMASRSFGGAPLVELTLEEDRAAVARLGRSEAEQRLLLSEPDLDLINAAILLRRPLLVTGKPGSGKSSLAYAIARELSLGPVLHWSITSRTGVKEGLYGYDALGRLEETNLRRIMGADTAPDLGEYIRLGPLGTALLPQKHPRVLLIDELDKSDLDLPNDLLHVFENGEFEIEEVVRQRGTDSVEVGVTGQPTPVTVHGGLVRCNAFPIVVLTDNGERDFSAAFLRRCVRLKLADPDRDRLVGIVEAHLGEEGVRTGRTLIEDFLVKRRAGTVATDQLLGAVYLAIAAKLGGTDRAELADRIMAPLDQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVQ3</accession>
    <name>C7PVQ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786588.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2377"/>
    <dbReference type="EnsemblBacteria" id="ACU71295">
        <property type="protein sequence ID" value="ACU71295"/>
        <property type="gene ID" value="Caci_2377"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2377"/>
    <dbReference type="HOGENOM" id="CLU_167343_1_0_11"/>
    <dbReference type="OMA" id="IAFRKIT"/>
    <dbReference type="OrthoDB" id="2087009at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982234" evidence="2">
        <location>
            <begin position="31"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="10794" checksum="813A212498367989" modified="2009-10-13" version="1">MFTGTVRRLFWVSMGATAGVLVFRKVTATAKELTPAGLADRAAISGGGLLDSVKEFFEDVRERAHDREEELNVALGIDVPPTSTDRDPEGDGFSKKARAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT7</accession>
    <name>C7PVT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CMP/dCMP deaminase zinc-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2411"/>
    <dbReference type="EnsemblBacteria" id="ACU71329">
        <property type="protein sequence ID" value="ACU71329"/>
        <property type="gene ID" value="Caci_2411"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2411"/>
    <dbReference type="eggNOG" id="COG0117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_8_2_11"/>
    <dbReference type="OMA" id="LRQKSWI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="164" mass="17933" checksum="98197B86F9DCE7F2" modified="2009-10-13" version="1">MTTIDAASPLSNRTRGEDREWLSTAVDLAWRCPPAPGAFNVGALIVDADDRELARGWSRDTDEHVHAEESALNTLGPNHPRLSGATVYSSLEPCSIRKSRPLTCTQLIIASGIRRVVFAWREPSLLVEDCQGAELLREAGIEVVEFPEFEPLVKAANAHLFGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVX6</accession>
    <name>C7PVX6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Alanine dehydrogenase</fullName>
            <ecNumber evidence="3 6">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_2450</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reductive amination of pyruvate to L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786661.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2450"/>
    <dbReference type="EnsemblBacteria" id="ACU71368">
        <property type="protein sequence ID" value="ACU71368"/>
        <property type="gene ID" value="Caci_2450"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2450"/>
    <dbReference type="eggNOG" id="COG0686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003376_3_0_11"/>
    <dbReference type="OMA" id="HPYYHLY"/>
    <dbReference type="OrthoDB" id="673280at2"/>
    <dbReference type="UniPathway" id="UPA00527">
        <property type="reaction ID" value="UER00585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008142">
        <property type="entry name" value="AlaDH/PNT_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00836">
        <property type="entry name" value="ALADH_PNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="11">
        <location>
            <begin position="149"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU71368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="39183" checksum="D7E0B5706D72AC4A" modified="2009-10-13" version="1">MKVGVPRELKNNEYRVAITPSGVHELVRNGHEVFVEKDAGAGSSLSDEQYVAAGAAILPTADEVWAVGDLILKVKEPIAAEYHRMRRDQILFTYLHLAASRECTDALLDSGITAIAYETVQLPDGSLPLLAPMSEVAGRMAAQVGAATLQKANGGRGVLMGGVPGVRAANVVVIGGGVSGINAAVIAKGMGAQVKLLDKSIHRLRQVDADQFGALQTLASNAFEIEQACLEADLVIGAVLVPGAKAPKLVSNELVSRMKPGSVLVDIAIDQGGCFEDSHPTTHAEPTFQVHDSVFYCVANMPGAVPYTSTYALTNVTLPYAVEIANHGWKEACQRDHALALGLNTHDGQLTYPQVGEAHDLPSLKLDEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW76</accession>
    <name>C7PW76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4461"/>
    <dbReference type="EnsemblBacteria" id="ACU73324">
        <property type="protein sequence ID" value="ACU73324"/>
        <property type="gene ID" value="Caci_4461"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4461"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110117_0_0_11"/>
    <dbReference type="OMA" id="IRWYTTI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="26987" checksum="CECE95B4616EE044" modified="2009-10-13" version="1">MTLSYDSVIISPVNGDSAAWTIDRLARLAAAALAAGAPTQPNGRIREVPDVRTIRWYTSIGLLGRPAAMRGRTALYGRSHLAQLVAIKRLQADGLTVAAVQERLLGADESAIEEIALLPADLEELITRVEGTQDAGEPERKPEPKAQTRARFWVAPVASTPADEEPAASALADHDALARSAAPASPAEPITAAPITAAPITTDAVSDIAVPVHGIRLAPDVTLLLPPGRVPDAAARAAIAEASRPLLDLLERLGLSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW91</accession>
    <name>C7PW91_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrate reductase molybdenum cofactor assembly chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793068.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4476"/>
    <dbReference type="EnsemblBacteria" id="ACU73339">
        <property type="protein sequence ID" value="ACU73339"/>
        <property type="gene ID" value="Caci_4476"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4476"/>
    <dbReference type="eggNOG" id="COG2180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084469_1_0_11"/>
    <dbReference type="OMA" id="YGDTRKR"/>
    <dbReference type="OrthoDB" id="1975985at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020945">
        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003765">
        <property type="entry name" value="NO3_reductase_chaperone_NarJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036411">
        <property type="entry name" value="TorD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43680">
        <property type="entry name" value="PTHR43680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02613">
        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89155">
        <property type="entry name" value="SSF89155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00684">
        <property type="entry name" value="narJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23911" checksum="BAD8FB0C503C604B" modified="2009-10-13" version="1">MGRVSGNGAPIGRREQVVLRAAAHLLDYPDAAWRERLPLVRSALAAVGGGAARTLVTFVDQASAMPAAEATAHYVEVFDFKNRHSLYLTWWLDGDTRRRGMSLVELKAAFREAGFEFVEAELPDYLPVVLEFSAVSGDLGLLVRHRPGLELLRLALAEHGTAYAAVVEAVCSTLPGASPKDRAAARALAAAGPPRETVGLDPDTAALRPYGHLDLLPVLAPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA2</accession>
    <name>C7PWA2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793079.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4487"/>
    <dbReference type="EnsemblBacteria" id="ACU73350">
        <property type="protein sequence ID" value="ACU73350"/>
        <property type="gene ID" value="Caci_4487"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4487"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059523_0_1_11"/>
    <dbReference type="OMA" id="YDSRPEL"/>
    <dbReference type="OrthoDB" id="1194699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="30328" checksum="203F731293DAEDCA" modified="2009-10-13" version="1">MIADRIAGAPISWGVCEVPGWGHQLSAERVLTEMAEAGLRATEFGPDGFLPEDPGERRALLKEYQLSAVGGFVPAVLHEAGHDPWPGVEEALGGFTASGADLLVLAAATGADGYDSRPVLDAVGWRRLFTNLDRIRARAVGLGIRTCLHPHVGTMIETGGDVERLLEASDTPLCLDTGHLLIGGGDPASLASRAADRIVHTHLKDVDAALAERVRGGELTYYDAVRAGMYQPLGRGDADIAGVVSALEGNGYQGWYVLEQDTVLDAEPGRGDGPAADVRACAAFLEGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWB9</accession>
    <name>C7PWB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4504</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793096.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4504"/>
    <dbReference type="EnsemblBacteria" id="ACU73367">
        <property type="protein sequence ID" value="ACU73367"/>
        <property type="gene ID" value="Caci_4504"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4504"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_21_3_11"/>
    <dbReference type="OMA" id="TFLAVQY"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="29"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="168"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="348" mass="35797" checksum="A88798530CB24A0A" modified="2009-10-13" version="1" precursor="true">MTSSTTPTARADHSRVTSPIPHRTDHRTDLALLLVAFVWGSSYLAAKSAAAATSVLAVLLARYALSAISGSALLAARRQLRPHRTELRIGTILGLTQASVLIIETYGVAHTSAANAGLIISLTIILTPLLDRRGAALPARYFAASGLCVVAVGLLMSGSGGLHMPSAGDLLMLAAAVVRAGHVALVGRLTATSDIRPLNLTVVQTYVGTALFAIPAATELPKLARAGASTWAEMAYLALFCSVFAFVAQTWAVRRTSASRASLLLGTEPVWAVAAGVALGGEHLAAPAVAGAALMLAGTYWGQAIERAHRARVALSLSLAWPTAPRPSAPPDARSPASGIPAGCTPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR7</accession>
    <name>C7PWR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796899.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8351"/>
    <dbReference type="EnsemblBacteria" id="ACU77174">
        <property type="protein sequence ID" value="ACU77174"/>
        <property type="gene ID" value="Caci_8351"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8351"/>
    <dbReference type="HOGENOM" id="CLU_905177_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="31920" checksum="A6EB7D410A495455" modified="2009-10-13" version="1">MTEFEDSADQGAEEDGSQTRELFARTAVQAYPRLAFTADDLVAEGRRRVRRRRMAAVVGSTASVAVVAVAAAAFAGGGGSGTAAVAPGASVTTSPRPALTTTDTAKQPLTDDERTLAERKLAAAVFAEVAGKLDPGGKHLTPSGVRVGKEDAFAPNTGVCVEKTKLQVSYGFNMDWTVTGQDPFPRHVDATSPYVDVSVEVFAPGKNVDQFGASQDWGPLTRTSLPDHSVVETGATAGGHRVQAVRTMGNGQQILVRALDGSTAPNVKTQPTNPFPYTAAQLGAIVGGVSLPLPFADGFQPHTSCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF3</accession>
    <name>C7PXF3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ordered locus">Caci_0567</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784799.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0567"/>
    <dbReference type="EnsemblBacteria" id="ACU69504">
        <property type="protein sequence ID" value="ACU69504"/>
        <property type="gene ID" value="Caci_0567"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0567"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_4_0_11"/>
    <dbReference type="OMA" id="VDACRQM"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="110"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="241"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="258"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="35000" checksum="009DFE17DFBD435C" modified="2009-10-13" version="1">MTTRAAVVQGVGGCVPPRSVDNNELSSRLETSDAWIRERLGIGRRYVADGVSTVDLAVEAGARALEMADAGAGLGPLDVVLLATTTPDRLCPASAPEVASRLGYTGIAAFDVNAVCAGFVHALATGNALIRGHMADRVLVIGADTFTTLVDPADRLTASIFGDGAGALVLRAGTPDEPGALRAFDLGSDGSQVATVEVPGGGARDRLGMPVANQRPYLVMDGPAVFRRAVQEMTASSLRVLAKAKWDAGSVRRFVPHQANIRIIRGVAERLGIGAERVVANIEDVGNTVAASIPLALADAHDSGRLGAGERVLMTSIGAGLAWGSAVLTWPELQGKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI8</accession>
    <name>C7PXI8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786734.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2523"/>
    <dbReference type="EnsemblBacteria" id="ACU71441">
        <property type="protein sequence ID" value="ACU71441"/>
        <property type="gene ID" value="Caci_2523"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2523"/>
    <dbReference type="eggNOG" id="ENOG5033AWP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132013_2_0_11"/>
    <dbReference type="OMA" id="FWIEAGA"/>
    <dbReference type="OrthoDB" id="2059119at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13450" checksum="D635156E8EA5986B" modified="2009-10-13" version="1" precursor="true">MKPQSLTEIALRVAIAGTLATSGYIHAQLYVSDYRYIHIVGVLFLLQASASFALAALVLAGGPIYVRIGAGGAAAGALGGFAASRTVGVFGFTEHGWQPSPQSLTSVLVEVATLLLLVPTGLEIVKRIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXR4</accession>
    <name>C7PXR4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LnmK_N_HDF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786810.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2599"/>
    <dbReference type="EnsemblBacteria" id="ACU71517">
        <property type="protein sequence ID" value="ACU71517"/>
        <property type="gene ID" value="Caci_2599"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2599"/>
    <dbReference type="eggNOG" id="COG0824">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857633_0_0_11"/>
    <dbReference type="OMA" id="YFSIVDW"/>
    <dbReference type="OrthoDB" id="1374993at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040718">
        <property type="entry name" value="LnmK_N_HDF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18238">
        <property type="entry name" value="LnmK_N_HDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LnmK_N_HDF" evidence="1">
        <location>
            <begin position="24"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="36322" checksum="F44936F2944EBBF1" modified="2009-10-13" version="1">MNAATPTLVPPASAPRLLQDGTLTRTELITPGKCGPNSLFVGCLGDWAWDAVSQACSVNAYDARDATGAPAYLSFSYFRIRGSRRINPLSLTFGDRLQVASKVFGQGSESVLTLHQVRHDDGKPPEPLDPERFHTSTDQNALYVEIFNRWISRTKPNSNQDLTRNAPVGFQYRHLPSVPPQYSPRLVFAQIRESGAFDPDPEPPRTVAELFYTEYRVEPSRDLNGVGLLYFASYFSIIDWSLLRLWRHLGRDDRSFLRRLVLDQRVCFLGNADADAVLDVALTRRSALTDPTDELIDLVLTEKPTGRVLAVAALRLHGEQRERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV2</accession>
    <name>C7PXV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73412">
        <property type="protein sequence ID" value="ACU73412"/>
        <property type="gene ID" value="Caci_4550"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4550"/>
    <dbReference type="HOGENOM" id="CLU_549462_0_0_11"/>
    <dbReference type="OrthoDB" id="2099442at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982661" evidence="3">
        <location>
            <begin position="37"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="496" mass="49457" checksum="4E64BA178D3C922F" modified="2009-10-13" version="1" precursor="true">MGTLATRLSATAAAIGLVGGVLATSSAVAAVPSAPAAPAVPASGSIPFSVADPDTAPRPVVTVAIGGVPLLLLLDTGSTGIRVAADKIPGKAVAVTGPAAAYGYGSGIQLHGDQADADVAIGENHTGPLPIELVRSTDCFTDKPDCPAAHGVKPAMFGGVLDGIMGVSPEEISGLVNPLWALHDAAGRHLGRQFAVRYDPAQVSGEVMLNVPAAGYGLVQLPRTPDAGSHHRGATSGYDARAYVSSYTGSYASRAGALRDGAPATNRPEAAALAMPPSWNPRAVQTCVEGTGLRKTCGPAMFDTGTPEFALNVPGGPAGVWPSGRSLVVGVPAAGWSAAYSTGAGNGVTVADEPSTAASGTLIGLPAFAKGPIRFDLEAGTVGFPVAAASNVASAATVPQQRGLVEAALAPAAVQPTPTPPPSTPSPTPSPTPKPKHVTPKKNYPRLPFHTGKKARSLPDTGVPMSAALGAVTALTALLAGIGTVLAARRRPDHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXW5</accession>
    <name>C7PXW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793154.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4563"/>
    <dbReference type="EnsemblBacteria" id="ACU73425">
        <property type="protein sequence ID" value="ACU73425"/>
        <property type="gene ID" value="Caci_4563"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4563"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_2_11"/>
    <dbReference type="OMA" id="MPHIDRS"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="16767" checksum="FE09BF9A63660DC7" modified="2009-10-13" version="1">MTASASTALTIQEVSRHTGLSEPTLRYYEEVGLVGPIDRDERSGHRRYRTADLDTVEVLACLRAVGMGIDDMRAYLANRRIGRTRAGEQRDLLLRHAERVEAEIAAQQARLGYLREKAVLWDARAKGDAVAEAASTERMVAVMERLEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY31</accession>
    <name>C7PY31_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4630"/>
    <dbReference type="EnsemblBacteria" id="ACU73491">
        <property type="protein sequence ID" value="ACU73491"/>
        <property type="gene ID" value="Caci_4630"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4630"/>
    <dbReference type="eggNOG" id="COG3332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047037_2_1_11"/>
    <dbReference type="OMA" id="AGGTWCA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="PTHR17985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="27707" checksum="72033764C97F34F1" modified="2009-10-13" version="1">MSVEPSSEYPVVLAGVRDEFHDRPWIPPGRHWPRYPRLIGGQDLLASGTWLAVDPDACRVACVLNGRGPLAPEAGRRSRGDLPLRFAAAGAGEDMERLDFTRYDPFHLICATVREVFLLSWDGEQHQRQDLAAGLHVVVNSGLEGTDPTDGPGTEAMAARLGFFRPRLLTARRPQPAPKVATRQAWEPWLPLLEGGGLDPLDDRALLVRREFGERTWGTTSVSLVALRASGGVRYDFSGTPGDPAAWSPVVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYP8</accession>
    <name>C7PYP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797095.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8550"/>
    <dbReference type="EnsemblBacteria" id="ACU77370">
        <property type="protein sequence ID" value="ACU77370"/>
        <property type="gene ID" value="Caci_8550"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8550"/>
    <dbReference type="HOGENOM" id="CLU_2394396_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="9980" checksum="F9DF0063B19C3315" modified="2009-10-13" version="1">MAMWATNGKRGLIPGTVGITITVIEYYAGTNTYQKVSSAAYRLDGVPQPATPHRSAESAPVSMVRPFIVAGLTERTPQRGGRRRSSASDGDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYQ7</accession>
    <name>C7PYQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA binding domain protein, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797104.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8559"/>
    <dbReference type="EnsemblBacteria" id="ACU77379">
        <property type="protein sequence ID" value="ACU77379"/>
        <property type="gene ID" value="Caci_8559"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8559"/>
    <dbReference type="eggNOG" id="ENOG5033IG7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_8_0_11"/>
    <dbReference type="OMA" id="TESIWHE"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7900" checksum="31D7CA6FEE33A330" modified="2009-10-13" version="1">MSQTRDRLLTVDQAADRLNTGPRFVRRLIAERRITYVRVGRHVRIPESAIENYVQAGTVAPIANRRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ26</accession>
    <name>C7PZ26_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proline dehydrogenase</fullName>
            <ecNumber evidence="3">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0646</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784877.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0646"/>
    <dbReference type="EnsemblBacteria" id="ACU69582">
        <property type="protein sequence ID" value="ACU69582"/>
        <property type="gene ID" value="Caci_0646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0646"/>
    <dbReference type="eggNOG" id="COG0506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061158_0_0_11"/>
    <dbReference type="OMA" id="YKESAAV"/>
    <dbReference type="OrthoDB" id="1746057at2"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008219">
        <property type="entry name" value="PRODH_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000196">
        <property type="entry name" value="Pro_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="8">
        <location>
            <begin position="46"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="188"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="227"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000196-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000196-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33917" checksum="A40735766E9B8FF6" modified="2009-10-13" version="1">MLSQTLLAASRSAKMRGMITGVPLTRRVVDRFVAGDNLDQASLIISDLVDQGLAVTVDRLGEDTQDAADAAATRDAYLEMLKRFADLGIAHRTEVSLKLSALGQKLPQDAEKIALENAIAIAEAARDAGTTMTLDMEDHTTVDATLGALRELRGEFPWVGVAIQAALFRTEGDVADLATAGSRVRLVKGAYMEPASVAHQEKHEVDKAYVRAMKTLMRSSAYPMIASHDQRMIDIAHALIAETGRAHDAQEFQMLHGIRTTEQHRLVDGGDTMRVYVPFGDDWYGYFMRRLAERPANVMFFLNSLVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ68</accession>
    <name>C7PZ68_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0689"/>
    <dbReference type="EnsemblBacteria" id="ACU69624">
        <property type="protein sequence ID" value="ACU69624"/>
        <property type="gene ID" value="Caci_0689"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0689"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_1_11"/>
    <dbReference type="OMA" id="IAMEYGE"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="42505" checksum="77844982DE06A20F" modified="2009-10-13" version="1">MSSTIEAGVGTEDIRKDTVFGRIGGALREREFRWWFAGQITSASGVMAQGVALSWWMLQRTGDAVWLSVLTVCTMGPTLIGGAWAGAVVDHADRRRLLIGTQTVLMGIAAALTVLAATDTLAVWNVLVASVLAGTTMAVDSPARQVYVVDLVGADGVASAVGLWEVALNTSRVVGPGLGGALLAGPGATACFGVNAFSYLAPLIVLLRMKPRTTAQVRTRGRARGAARDGIRYAFRSPVIRALLPMSTASGLIFGMGIALPPLVQRALHQGGGGYGAMMAAFGVGGLPGALLAAAQPEPTGRRVRWLALATAAAVIGTAVAPVMAVALVGMVALGLTSIWFIASANTLAQLRCAPDMRGRVMSLWGVAMMGTAPITGFGVAAVVQYVGPREGFSISGIALGLAAVVGWRALRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ85</accession>
    <name>C7PZ85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786835.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2625"/>
    <dbReference type="EnsemblBacteria" id="ACU71542">
        <property type="protein sequence ID" value="ACU71542"/>
        <property type="gene ID" value="Caci_2625"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2625"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="NVYINGP"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="29"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="50873" checksum="0D787A6B5816AFB7" modified="2009-10-13" version="1">MSTETYPWSGTLFVDGQFRSALAGGAFGIRDKATDEVFAEAGAATVQDVDAAVASALTAQKAWAQASFAERASVLRQAAATLREAPELRELIMRETGCIGGKADYEIGAAASELIEAAALASRPLGEVLRTTHAGRLSISERRPVGLVAAITPWNFPLVLGMRVIAPALALGNAVLLKPSPETPACGGLEIARIFAEAGVPAGLLQVLPGGEEVGRRLVEHPDVAMVHFTGSTKVGREIARTAGGLLKKTSLELGGNNALIVLEDADVEQAAMMGAWSTFHYQGQTCITAGRHIVHRAVAEAYIENLTARAAAISLGDPVRESVGLGPMINDVQVARARRLLDDAVAGGARVLTGGTNEGNFFRPTVAVDIDVKSALWTEEIFAPIAPIVIVDTDEEAVELANDSGYGLVSSVVGADERRAGAVARRLNAGMVHVNDATPQDEALAPFGGIGQSGLGGRAGGDSNIEEYTELRWLTVDSLPVHYPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI9</accession>
    <name>C7PZI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786939.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71646">
        <property type="protein sequence ID" value="ACU71646"/>
        <property type="gene ID" value="Caci_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2732"/>
    <dbReference type="HOGENOM" id="CLU_1243469_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="23781" checksum="BC5BC66A4BC6B60D" modified="2009-10-13" version="1">MTVPTRIAAVPELEERFVRRSLWVLGCWVMLLYVLWEAWELYAPWRTQAFLRAAGFRGVSFDAAQESTQRNASSAPLLVAVAVFAVCGAVTVATARNIRVTAARDVRRVTAAMIVVMTLAVAGPAVNQVRTAADMGHRLSTLPHVTQSSVDDVARHAGVSVTVLGNVDYNLAGQRVHLPGPVLVLGRAGSHTTGTVYGVDAVTGKAFTVSPDQKITYSDGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZL6</accession>
    <name>C7PZL6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793260.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73531">
        <property type="protein sequence ID" value="ACU73531"/>
        <property type="gene ID" value="Caci_4670"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4670"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="INNPFFP"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="34510" checksum="566CFB172F3AA3BA" modified="2009-10-13" version="1">MAVTINEVAKAVGVSTSTVSRAFTAPDQVRPETRERVLEVSAELGYVPNPSARSLRAGATATLGMIIPDLANPFYPPIFKALQQRARHLGYTTLVADCDDRESAELDAIAAIANRVDGLLLFASALPEERLRAIAAQTPLVLVNRDVPGISSLRIDLTAGVRQAGELLYALGHRRCALIDASRPGYERDKLFAEIFRGLGLTVVELGPYEPRFESGVHAATLVATGGATAVLAHNDLVALGALQQFTALGVRVPADVSLVGIDDTLLASVCTPALTSVRIDPEELAAAAAELLLEAVTGRGDSPRQVVIGTRLVSRASTGPAPAPTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q038</accession>
    <name>C7Q038_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endoglucanase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6685"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75531">
        <property type="protein sequence ID" value="ACU75531"/>
        <property type="gene ID" value="Caci_6685"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6685"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043519_0_0_11"/>
    <dbReference type="OMA" id="TWNTWDC"/>
    <dbReference type="OrthoDB" id="1395441at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982382" description="Endoglucanase" evidence="5">
        <location>
            <begin position="43"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="6">
        <location>
            <begin position="41"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="533" mass="55074" checksum="95FF0E88722487CB" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q052</accession>
    <name>C7Q052_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795274.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6699"/>
    <dbReference type="EnsemblBacteria" id="ACU75545">
        <property type="protein sequence ID" value="ACU75545"/>
        <property type="gene ID" value="Caci_6699"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6699"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_5_2_11"/>
    <dbReference type="OMA" id="QWIYTHG"/>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23384" checksum="083D8FAC0A94E4E8" modified="2009-10-13" version="1">MSERSARCAATGSGVNATDSPAIEVNTVAEIAEAAETTDWRRLDSVVVLATPWFDVRQDAVIRPDGAADVYHHVATPGSVTVLPVAEDGRVLLTRQWIYTHGGVQWRLPAGTIERFDERPVAAARRELAEETGLRAARWVALGAVNGADSLTNHVDHVFVAQELTQGEAAREGGEADMALCWLSFEQALELVWSGQIRHAGSAYALMSFKHLREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q085</accession>
    <name>C7Q085_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795307.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6732"/>
    <dbReference type="EnsemblBacteria" id="ACU75578">
        <property type="protein sequence ID" value="ACU75578"/>
        <property type="gene ID" value="Caci_6732"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6732"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_5_11"/>
    <dbReference type="OMA" id="IEGNWIT"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982660" evidence="2">
        <location>
            <begin position="25"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="43756" checksum="E74D68E7A1EAFC1D" modified="2009-10-13" version="1" precursor="true">MKSVRTRRIVAVAGAAAVLVTAAACGSSGPSKSTGSSSSGGGTGGATSGVTLQVLIGSSGDAETNAVVAAGNAWAAKTGNKVVVTPAKDLTQQLTQSLAGGTPPDIFYVDASKFQSLVKGNALADVGSKITDSADMYPNLQQAFTANGQYYCVPKDFSTLALEINSDLWTKAGLTDADVPTTWDQLETVAKKLTGNGVTGLVMSDTLDRIGAFMRQAGGSVVSTDGKTVTADSPQNLAALQYLQKLGKEGALKFPKQVDAGWGGEALGKGKAAMTIEGNWIVGSMQKDYPNVHYKVVPLPAGPAGKATLSFTNCWGVAQKSSHQAAAVDFIDYLTTVDQQMSFAKAFGVMPSRQAAKSQFTTAFPDQAAFVTGADNAFGPVGFPGFDAVQKDFDSKIQGLSDGSSDPKSMLSSLQKNASDALSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S1</accession>
    <name>C7Q0S1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784994.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0764"/>
    <dbReference type="EnsemblBacteria" id="ACU69699">
        <property type="protein sequence ID" value="ACU69699"/>
        <property type="gene ID" value="Caci_0764"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0764"/>
    <dbReference type="HOGENOM" id="CLU_989338_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="28803" checksum="22E066FF933EF9AC" modified="2009-10-13" version="1">MEETDVGRVLAAAAPDTVPTVAGLPERARALGRRRRRRRAALTTGGTGLALAGVVGAVVALGGFGGGGQPVRATSSPGHRHTDGGPGVPVPKPSTPMPTSPVPTTPASSSGAPTGSPTPSKPVLPSASDDPAADAKVLTAIKAALPAKDRDKPTLYRAAGEQNGYGAEYNWGPRSQESTLGVSVGSISPVLPGSDPTMCQSDTAHCTFGNATLHGDPVVWQYYYGSLSSPSLNIYDYKAMIGYLITADAPNASHLPDMTEMKDIGLNEQVASALLAAWPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1E4</accession>
    <name>C7Q1E4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_4812</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793402.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4812"/>
    <dbReference type="EnsemblBacteria" id="ACU73673">
        <property type="protein sequence ID" value="ACU73673"/>
        <property type="gene ID" value="Caci_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4812"/>
    <dbReference type="eggNOG" id="COG0004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_0_11"/>
    <dbReference type="OMA" id="PHNVPFI"/>
    <dbReference type="OrthoDB" id="562287at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="11"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU73673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="465" mass="48134" checksum="82C0378717C1F62E" modified="2009-10-13" version="1" precursor="true">MPSAFNSGDTAWVLASSAMVLLMTPALAFFYGGMVRAKSVLNMLMMNFIAIAVVTVAWVLYGWSVAFGNVGAGKGGGNGLWGGLHQWALHDIGMGFGTSPGGGAAGGGSLFGTTGVPTIAVVCFQLMFAIITPALISGAIADRTKFVGWTVYVAAWVTIVYFPVAHWVFSPNGFIFWKLHVMDFAGGTAVEINSGAAGLAMALVLGKRIGYRRDPMRPHNVPLVMLGAGLLWFGWFGFNAGSALAANGQASMVFVNTQIAGCTAMVGWLIAEKIQHGTFTSLGAASGAIAGLVAITGSCASVSPLGALFVGLIAGFVCCYAVNLKHRFGFDDSLDVVGVHLVGGIVGVLLIGLFATKEMAGGFINGARAGLFYGGGFTQLGRQAEGAGIVFLYSFVLSLLLGFAVHKTIGLRISAEAEVEGIDGAEHSETAYDWGRLAGSLRTALTDHDEHAAKQPVQGGESVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1G8</accession>
    <name>C7Q1G8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MnhB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_4836</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793426.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4836"/>
    <dbReference type="EnsemblBacteria" id="ACU73697">
        <property type="protein sequence ID" value="ACU73697"/>
        <property type="gene ID" value="Caci_4836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4836"/>
    <dbReference type="eggNOG" id="COG2111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942774_0_0_11"/>
    <dbReference type="OMA" id="DIARHAM"/>
    <dbReference type="OrthoDB" id="1792213at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007182">
        <property type="entry name" value="MnhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04039">
        <property type="entry name" value="MnhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="MnhB" evidence="9">
        <location>
            <begin position="176"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU73697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="35148" checksum="5E8C845E13D86A39" modified="2009-10-13" version="1" precursor="true">MSRRAGADHEPHHRVAAGALLTAGMAAVLAVGFLRLQRDHAALPPVARYALEVALPRWKLSEPVNEVVYGTRGFDTFGETFLLLAAVISVIVISRPREPRRGYFGEETAGRREQAEVDPHERRDQEEEQARAAEKEEAGEPDDAVGGAAGLRRPETPDAEPVGSPAPERAHAMSVVIRTAIRTAAPVLAVTGLYLVAWGYSPGGGFPGGAVMLGVALLVYAGFGRKRIAGVIRPGLLEGIEMAGAALIIGAETLGLLLKGSFSANWLPLAPVGTIRSGGVAQLFSVGELIEVGTGLMIAVFAVLGMTHDWTPDEDGDSDGEDNQGPDQSGGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1L2</accession>
    <name>C7Q1L2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucanase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_4881</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase family 6.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793470.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4881"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH6">
        <property type="family name" value="Glycoside Hydrolase Family 6"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73741">
        <property type="protein sequence ID" value="ACU73741"/>
        <property type="gene ID" value="Caci_4881"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4881"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015488_3_0_11"/>
    <dbReference type="OrthoDB" id="1331351at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016288">
        <property type="entry name" value="Beta_cellobiohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036434">
        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001524">
        <property type="entry name" value="Glyco_hydro_6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34876">
        <property type="entry name" value="PTHR34876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01341">
        <property type="entry name" value="Glyco_hydro_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00733">
        <property type="entry name" value="GLHYDRLASE6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51989">
        <property type="entry name" value="SSF51989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00655">
        <property type="entry name" value="GLYCOSYL_HYDROL_F6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 7" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005125744" description="Glucanase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="458"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="554"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="10">
        <location>
            <begin position="639"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="378"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU73741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="743" mass="75850" checksum="229F6CC13F163C8F" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S8</accession>
    <name>C7Q1S8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795358.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75629">
        <property type="protein sequence ID" value="ACU75629"/>
        <property type="gene ID" value="Caci_6787"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6787"/>
    <dbReference type="HOGENOM" id="CLU_2128988_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="11357" checksum="476392752585AE78" modified="2009-10-13" version="1" precursor="true">MRQSWILIVLGLLLIGGAAYVGLHHSHLDIDVGTSGITVAHVRVDCGSPLSRKYPLPAGLQYQGKGPCASSTALARQLTGSALAAAAGVGCLVMGITGLVRRPAAAPSAVSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q251</accession>
    <name>C7Q251_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797312.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8773"/>
    <dbReference type="EnsemblBacteria" id="ACU77588">
        <property type="protein sequence ID" value="ACU77588"/>
        <property type="gene ID" value="Caci_8773"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8773"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="WMWGPPV"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="27252" checksum="6782E61A560EC7AA" modified="2009-10-13" version="1">MLLEGKTVIVSGVGEGLGREVAQAAYDQGANVVLGARTEAKLAKAAAEFDSARVAHATTDITSDDDCRRLVALAVERFGGLDGLVNVAAMDQVFGGVSDADFADWRAVYEVNVVGTLQLSKAAIPHLARESGATTGIVHILSQSMWVPATEVMQAAYAASKGALLSATYGMAKELGPRRIRVNAVVPSWMWGPMVQGYVAWTASSQGIAEEQVLSSLTDRMALPEMASDGDVANAAVFMVSPYAGGITGQSLAVNAGDYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M5</accession>
    <name>C7Q2M5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ordered locus">Caci_0935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785162.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0935"/>
    <dbReference type="EnsemblBacteria" id="ACU69867">
        <property type="protein sequence ID" value="ACU69867"/>
        <property type="gene ID" value="Caci_0935"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0935"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_11"/>
    <dbReference type="OMA" id="FPEMVGH"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="10541" checksum="EE9682214E99791E" modified="2009-10-13" version="1">MPRSLKKGPFVDGHLIKKVDAQNAKNTKTVIKTWSRRSMIVPDMLGHTIAVHDGRKHVPVFITEAMVGHKLGEFSPTRTFKGHVKDDRRSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2T4</accession>
    <name>C7Q2T4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787119.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2917"/>
    <dbReference type="EnsemblBacteria" id="ACU71826">
        <property type="protein sequence ID" value="ACU71826"/>
        <property type="gene ID" value="Caci_2917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2917"/>
    <dbReference type="HOGENOM" id="CLU_2536414_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="8914" checksum="63AE8872752C8F6F" modified="2009-10-13" version="1">MTAAWVACECDATPCICYIPPPQIGPADRAEAERLRDEMAASGSDARAWFANFIDENSDELAEALSRPVEDLIAEALAAREGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q324</accession>
    <name>C7Q324_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4900"/>
    <dbReference type="EnsemblBacteria" id="ACU73760">
        <property type="protein sequence ID" value="ACU73760"/>
        <property type="gene ID" value="Caci_4900"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4900"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="HMREQGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="32400" checksum="E4CD91C6FE2B4D26" modified="2009-10-13" version="1">MFGKLLTAVTTMPKLCRMILTDKVAVVTGSGRGLGLAYARALAAAGAAVVVNDVDADAARAAAAQIEAAGGRAVAEVAAVGTTEAADALVRRAVDSFGRLDVMVTNAGVLRDKVLWKMSDEDFDTVVQVHLRGTFTCARAAAAHMREQGTGGRIIVAGSPAGQRGNFGQTNYSAAKAGIAAMVRTWSMELARADITANAVIPVAATAMTKTIAAFAPHVEALEDHGTPLPDALRKGEGFGTPEDAAPLVVFLASDAAAGITGQCIGIGGDKLALWSHPQEISVAYADGGWSAEAIAAAWPVSVGRTPETVGVPAPGTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q332</accession>
    <name>C7Q332_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793497.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4908"/>
    <dbReference type="EnsemblBacteria" id="ACU73768">
        <property type="protein sequence ID" value="ACU73768"/>
        <property type="gene ID" value="Caci_4908"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4908"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_0_2_11"/>
    <dbReference type="OMA" id="PEWAVTV"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="27369" checksum="7BED63D372FCA80D" modified="2009-10-13" version="1">MTVALLAAVVEIAAEAGRALEARYSTATRPAGRQDMFRIGTADGQVSLDILRPALTALRPEARWLTDEYETTALPPGEWWVVDEVEGNVNHVHGLPEWAVTVALVRDGQTVLAVVRQPVGDLTYTALRGGGAHLNGAPLTVSAKTDLDAAIVVTGQAEADQDGTYRRIGESITAMLQRALLVRATVPSTFPMLLVAAGHNDVFWQYEPVLPGVAAGALLITEAGGVVTRIDGTPWSPGADTVVATAPALHAATVEVLATVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3D8</accession>
    <name>C7Q3D8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6863"/>
    <dbReference type="EnsemblBacteria" id="ACU75703">
        <property type="protein sequence ID" value="ACU75703"/>
        <property type="gene ID" value="Caci_6863"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6863"/>
    <dbReference type="HOGENOM" id="CLU_1052485_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021235">
        <property type="entry name" value="DUF2637"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10935">
        <property type="entry name" value="DUF2637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="28291" checksum="122601CF621192EB" modified="2009-10-13" version="1">MTDQHQDHGNLANAIRVARIGGTIAELAAAAISADTLYHLGGQLDLGPASAWLLPAALDVYAFTALAVAYNLPVEHPGQKPVLRNARLAFSMSLACNALDHFLKRAGRLVDPLTRDLLLVAVASLPPLIVERLLNLQSLLTRSRGRSAQSGRVEAAPEEEEPARMGEEALAHAAAAEEEAEPQLARPPDQEVVWTGRPDWVAHGREIFANLSTQLSRRPSGREFQAALAAETRRLSTSGHLPAGTRPPSISSAKRIRAAIEADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G4</accession>
    <name>C7Q3G4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795457.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6891"/>
    <dbReference type="EnsemblBacteria" id="ACU75729">
        <property type="protein sequence ID" value="ACU75729"/>
        <property type="gene ID" value="Caci_6891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6891"/>
    <dbReference type="HOGENOM" id="CLU_2786262_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="7695" checksum="0573EA31CEAF14EC" modified="2009-10-13" version="1">MEDLLKHATARMSALWSRRQEAAERLREDRGSVSVENVLWTAVYATMAVTIGAVIYQLVFAKAQSLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S5</accession>
    <name>C7Q3S5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797407.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8870"/>
    <dbReference type="EnsemblBacteria" id="ACU77683">
        <property type="protein sequence ID" value="ACU77683"/>
        <property type="gene ID" value="Caci_8870"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8870"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="CYRMTGV"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="15"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="110"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="32795" checksum="6A6C04D4AD448131" modified="2009-10-13" version="1">MNERTLEESATETFVAHRNLLFTVAYEMLGSAADAEDVLQETWLRWTTVDLDTVRDRRAYLVRITTRQALTQLRKLGRRKESYVGPWLPEPLLTTPDVAEDVELADSVSMAMLLVMETLTPAERAVFVLRDVFSLEYEEIAEAVDKTPAAVRQIAHRARNHVAARRPRGVTSTSDARCATEAFQKAVNTGDLQSLFDLLAPDVVFIGDGGGVVQATPQPLYGIEVVSRFMADGLSHLGAFVTMETAYVNGGLGVIIRAGGAVDTIVAMHTENGLITGIYVVRNPEKLSRVEEETAMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3X1</accession>
    <name>C7Q3X1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8916"/>
    <dbReference type="EnsemblBacteria" id="ACU77729">
        <property type="protein sequence ID" value="ACU77729"/>
        <property type="gene ID" value="Caci_8916"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8916"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_5_11"/>
    <dbReference type="OMA" id="ARAWQHW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="16"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="100"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18716" checksum="A2BFC08A929165D1" modified="2009-10-13" version="1">MSQEQDFDEFYLGSVRRVTAQLVAMLGDPVEAEDAVQEAYARAWQRWDSVSRMDDPVAWVRLVAYRIKVSSWRSAVRRTVAHRRHGPPPDVPDLSPDSVALVTALRGIPEAQRRAIVLYHLAGLTVEQVAAEVGAPVGTVKARLSRGRAALAQVLSESKDGDLKGRPSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q407</accession>
    <name>C7Q407_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797489.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8952"/>
    <dbReference type="EnsemblBacteria" id="ACU77765">
        <property type="protein sequence ID" value="ACU77765"/>
        <property type="gene ID" value="Caci_8952"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8952"/>
    <dbReference type="eggNOG" id="COG0645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103307_0_0_11"/>
    <dbReference type="OMA" id="YAYYFDI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21326" checksum="C919E2F60A5A153A" modified="2009-10-13" version="1">MTNVATTLLVLRGPSGCGKSTTATQLRESYGGRGLAIIRQDEVRRNVLRERDQDGAFTVTLIDIMARATLAAGIPCVVEGILSARIYGPMLERLLADHPRSFAYFWDVPFEETVLRHYTKPNHHEWSVEDMRNWYTPHDLLPSGVERIIGEQDCQQESVARIVVETALLTTPRPPYATLAPDPVTAAPSSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M3</accession>
    <name>C7Q4M3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine dioxygenase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787285.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3083"/>
    <dbReference type="EnsemblBacteria" id="ACU71992">
        <property type="protein sequence ID" value="ACU71992"/>
        <property type="gene ID" value="Caci_3083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3083"/>
    <dbReference type="eggNOG" id="COG5553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102185_2_0_11"/>
    <dbReference type="OMA" id="YSPPLWR"/>
    <dbReference type="OrthoDB" id="1571420at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="18281" checksum="0631EEE95AC2FA8B" modified="2009-10-13" version="1">MSSALQTPDLDVAEAFLHDLVIPDRPLWTPTQLRDLTRALADVHGDRLRPLVRHTEPQRWWTRLALTRGVEVWLLSWLPGQGTKPHDHGGAAGSFAVLSGEVQEEHRYPGGPIGVRRLQVGDALGFGGDRAHIVRQTGIRPAATVHAYSPPLLPTREYESLEDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4W6</accession>
    <name>C7Q4W6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protease inhibitor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I16 (SSI) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793643.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73914">
        <property type="protein sequence ID" value="ACU73914"/>
        <property type="gene ID" value="Caci_5054"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5054"/>
    <dbReference type="eggNOG" id="ENOG50344DV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1774030_0_0_11"/>
    <dbReference type="OMA" id="DLACFTV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="SSF55399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982887" evidence="3">
        <location>
            <begin position="29"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="SSI" evidence="4">
        <location>
            <begin position="75"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="14818" checksum="2B71EA43123B122B" modified="2009-10-13" version="1" precursor="true">MHTLAKAATSLLTAGSAAVILSAGTAHATLTTPTATTFLGAFHLTRTGFAGDAGATDLACFTVQGGEQAPTVLGAGAVTDPDAACRELAVADGDPALLLVHPAWTTSDLVAPVTVTVSGSWGPADVSWSHTFLNSSQLAKYTGDVFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W2</accession>
    <name>C7Q5W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70059">
        <property type="protein sequence ID" value="ACU70059"/>
        <property type="gene ID" value="Caci_1133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1133"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="HRHLQLF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22309" checksum="F4E3E48140F6E59D" modified="2009-10-13" version="1">MDVVAATARRAPRARALRVDALRNRERIVAAARDLFTEVGSQAPIDEVARRAGIGNATVYRHFPDRDALVLAVVRSVLKRTGDRAEAALAQGHDPFDALTRFVLAAADEQIGAMCVMLDGAYDPGDPEVKALEGRLNGLVETMLARAKHAGMLRADVDLADIIVAVAQLTRPLPDLVTVRRSSRRYLQLFLDGLRTPAHSTLPAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q667</accession>
    <name>C7Q667_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3165</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3165"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM16">
        <property type="family name" value="Carbohydrate-Binding Module Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72073">
        <property type="protein sequence ID" value="ACU72073"/>
        <property type="gene ID" value="Caci_3165"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3165"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_233414_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982555" evidence="2">
        <location>
            <begin position="40"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="1218"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="3">
        <location>
            <begin position="1534"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2031" mass="209021" checksum="B274C99ED10216E4" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q683</accession>
    <name>C7Q683_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3181"/>
    <dbReference type="EnsemblBacteria" id="ACU72089">
        <property type="protein sequence ID" value="ACU72089"/>
        <property type="gene ID" value="Caci_3181"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3181"/>
    <dbReference type="eggNOG" id="ENOG5031CVU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139649_0_0_11"/>
    <dbReference type="OMA" id="TQTMKPA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046039">
        <property type="entry name" value="DUF5997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19460">
        <property type="entry name" value="DUF5997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18251" checksum="96C825C1AE8EC2C3" modified="2009-10-13" version="1">MTSQKSTQTMKPATAAKKLGVYLEATPEAFQEGVVSRDELDALQADPPEWLRDLRRDGPHPRPVVAAKLGISISGLSRGGVEEPLTTAQIDALKADQPEWLRSERAIQAEVRRETVRVKEKAAAEEKKAANKAAAPPQRPSARSGTHDPRGAKGKGTRGTRGGTTRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D1</accession>
    <name>C7Q6D1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787430.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3230"/>
    <dbReference type="EnsemblBacteria" id="ACU72137">
        <property type="protein sequence ID" value="ACU72137"/>
        <property type="gene ID" value="Caci_3230"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3230"/>
    <dbReference type="eggNOG" id="COG1452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005386_0_1_11"/>
    <dbReference type="OrthoDB" id="70058at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="PTHR10412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="891" mass="101187" checksum="B1013CA3F7DCB0F6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6L6</accession>
    <name>C7Q6L6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="4" type="ordered locus">Caci_5192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5192"/>
    <dbReference type="EnsemblBacteria" id="ACU74051">
        <property type="protein sequence ID" value="ACU74051"/>
        <property type="gene ID" value="Caci_5192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5192"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_1_0_11"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="23259" checksum="2CDC4B38F5301E80" modified="2009-10-13" version="1">MSDSDSGTARPITIVGDPVLHRPCAPVEEFDDRLAGLVADMFASMYAAEGVGLAANQIGVPLRVFVYDCQDDDGVEHVGHVVNPVLAEQPPDRRQLDDSAEGCLSVPGPHHELARPDYARVTGVDLHGEPITVEGTGYFARCLQHEFDHLEGRLYIDRLSKRQRKNVLAEMERMQEEKAKRAAEPTETKEAKEAKEAKETKTAGTGKSSAPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Y4</accession>
    <name>C7Q6Y4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7168</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795725.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7168"/>
    <dbReference type="EnsemblBacteria" id="ACU75997">
        <property type="protein sequence ID" value="ACU75997"/>
        <property type="gene ID" value="Caci_7168"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7168"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="MGPWTDI"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="37479" checksum="5B392B2C1CCD353B" modified="2009-10-13" version="1">MVEQPSQAVVPAGLSGHRIAGYQLETEIGRGGMAVVYRAQDLALGRVVAVKLLAPELALNESFRLRFASESRAAAAIDHPHIIPVFSAGESEGVLYIAMRYVEGRDLRTLLDRNGTLPVLQAVRITTQIASALDAAHAHGLVHRDVKPGNILLAEGTDREHPEHVYLTDFGLTKKSSSLTGFTRVGQFVGTVDYVAPEQISGKPVDGRGDQYSLGCLVFELLTGSAPYHHDEDLALLWSHLHDPPPLLTDTRPGLPLALDAVLARALAKEPRDRFGTCMEFALALRAAGTPVVGHDPTRVAAAVGDVVGEVAARRPTPQLPEAEIEEQIPLPPAWAMPVFANAAVRRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q701</accession>
    <name>C7Q701_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795742.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7185"/>
    <dbReference type="EnsemblBacteria" id="ACU76014">
        <property type="protein sequence ID" value="ACU76014"/>
        <property type="gene ID" value="Caci_7185"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7185"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072253_0_0_11"/>
    <dbReference type="OMA" id="YGLWITR"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025847">
        <property type="entry name" value="MEDS_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14417">
        <property type="entry name" value="MEDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MEDS" evidence="1">
        <location>
            <begin position="18"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="34686" checksum="E667F78ECA906626" modified="2009-10-13" version="1">MSRLPFAAQTLDTAEPFRHEAFLYSGDEHFLAGTTAFVTAALDVGEAVLVAVVEPRATLLRHALGRDADRVEFLDLTRAGRNPARIIPAWQDWVDRNAATAKGFRGIGEPAWAGRTPSEIAECQHHERLLNTAFDDGPGWWLLCPYDLDVLPAPVIEHAHGSHPSVVAQDTRARSATYPQAGLAHPVFDEPLEEPTGPVWELVFDLASLKDLRDHVAEFAEPVVSAQDVDNAVLVVSELAANSIKYGGGAGVLRLWRDVASLVCEVRDNGVITDPLAGRRRPTGLGGKAGLWIANQVCDLLQIRSAPGLGTVVRARLGGAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q707</accession>
    <name>C7Q707_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LapA_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7191"/>
    <dbReference type="EnsemblBacteria" id="ACU76020">
        <property type="protein sequence ID" value="ACU76020"/>
        <property type="gene ID" value="Caci_7191"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7191"/>
    <dbReference type="eggNOG" id="COG5416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1479530_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="7">
        <location>
            <begin position="61"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19392" checksum="6BD9CF9C3CC3D683" modified="2009-10-13" version="1">MASIAPQEPDPAGGAPVPDTGETPTEPQHPPLPGRTRLGGLWVVLTAGAVVLVLLLVFILQNDQHVQIHLYGAHWNAPLGVALLMAAALGVLLVVVPGAGRIIQLRRAARNLHQDRERLLDQVPQEPQTPQTQTSQTPQTPQTPQTPQTSQGPQPSQVPLPQAPRPPQPEVGTPEAPAPREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q719</accession>
    <name>C7Q719_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7203"/>
    <dbReference type="EnsemblBacteria" id="ACU76032">
        <property type="protein sequence ID" value="ACU76032"/>
        <property type="gene ID" value="Caci_7203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7203"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_3_11"/>
    <dbReference type="OMA" id="DESLYWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="27521" checksum="31E7ED225DFAFA89" modified="2009-10-13" version="1">MTGSETRPARKVATAKRDRVRDHLLQLIDTAAPGTSLDSERDLAETLGVSRPTVRAALQDLARSGYLVRHQGRGTFTSPRKIDQALTGDSADGAAALAAPSAEGTWTSHVVTFRTSAAGPSRATRFDIAVDAPILRIVRVRLVEGEPIAIERLDVPAALVPNLKPDDVESGNFYHLLRDRHGIVVSDAVQTMEPTVANPEQAELLDIEVYAPLLQVERTTKDTTGRVVEFAHSVYRGDRYRITTRLHLDATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q759</accession>
    <name>C7Q759_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1222"/>
    <dbReference type="EnsemblBacteria" id="ACU70147">
        <property type="protein sequence ID" value="ACU70147"/>
        <property type="gene ID" value="Caci_1222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1222"/>
    <dbReference type="HOGENOM" id="CLU_570733_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="478" mass="49333" checksum="62F600307894805F" modified="2009-10-13" version="1">MDTWDNARPDRDQPTDGASAIPEEGSRGTSETTPAAASKSSAASEEEPYALPELRRALNIIADHYTSVPQPDLFPKVMARATRIRRRNRAIRAVTATAALVVAAILGPSVASELGVRGGDASAAPPPSAIVDLTSAYPVTAAAQSGVAVAMPTQPDNALNWPSRGTTVPAQAVDVAKSYLLDHAGSSATSATATVTTLWAQVDADTTVPSVKRAPKATPMPQAQAQAPQKAAHKTWLYVMQGWTNGPDGTPSQAELLVGDYTQTGKASSMSVYSSPVTFAHPRPGSADDIDDVQQIAELSVYLPQSDRLVVLGTPQTETVLYAKTGGDLVPQKTDGGVAVFPRTKELVKGHYADTIQVRDAKNVALTPPKAWSAADFVLSGMMSLWNSAGNGWVTVPLRSGAARPTQDSGTEASSEPSTGPSAEPSTGPPTQTQPPRLTPTGAPSVTPPSPSESVGAATAPSGQPTDTSGATGLASTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q786</accession>
    <name>C7Q786_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785468.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1249"/>
    <dbReference type="EnsemblBacteria" id="ACU70174">
        <property type="protein sequence ID" value="ACU70174"/>
        <property type="gene ID" value="Caci_1249"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1249"/>
    <dbReference type="HOGENOM" id="CLU_989339_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="28736" checksum="CDF214769B86BC7B" modified="2009-10-13" version="1">MNEEDFDGSALRELLAPAVADRGRTSAPTDAIVAAGRRRVLGRRSAVAGGALAIVAAVPLAATAIAAGPGTARTTSTAGGGTPGVVAPPHTGVVVPPPAKESESAPAKADPQGKPASGLPAQPTVFATGTVEGRQWKVTAETAPGNNALTAGEKCLGFVITVDGQNPLRGTAPTIPYCLPVKDPANALWGYQEWLKYDYEHAAGTLQMGMVKADVAKIVAHVDGLAPVTAETIPAPGLPEQAFYFLPIAKDNGFGVTFDEYDAQGVKIGTFDNSTPKPYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7B3</accession>
    <name>C7Q7B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1276"/>
    <dbReference type="EnsemblBacteria" id="ACU70201">
        <property type="protein sequence ID" value="ACU70201"/>
        <property type="gene ID" value="Caci_1276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1276"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046120_0_0_11"/>
    <dbReference type="OMA" id="QPRNMSM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="33"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="35012" checksum="C77F1F093484DFA4" modified="2009-10-13" version="1">MRQRPQIPGMAAGGGPGLPASALRGVVDLGALAAKPQAAPAATAQGPGAGTGGEGSGPAGGGTDAIASPLVFDTSDATFDTDVIERSLTVPVVIDFWAEWCGPCKQLSPLLERLTVEYGGRFVLAKLDVDANPALAQEFGIQSIPMVMAVVGGRLVPLFPGAVPEAQVRRYLEELLRLAAENGVTGTADGQAPEELPEPPMDPALAAAYTALEENDLDGAAQAFRNVLNANPGDTEAKLALAQVELMLNTRDLDVDQVRADAEAKPDDAAAQIAAAELDLSTGRVDEAIDRLVGFVARSAGADRDAARVKLLDFFELLGPEDPRTATGRQKLTRVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C6</accession>
    <name>C7Q7C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1289</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785508.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1289"/>
    <dbReference type="EnsemblBacteria" id="ACU70214">
        <property type="protein sequence ID" value="ACU70214"/>
        <property type="gene ID" value="Caci_1289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1289"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_9_0_11"/>
    <dbReference type="OMA" id="KGPYKDK"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982988" evidence="2">
        <location>
            <begin position="34"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="116"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="610" mass="64988" checksum="BC8341F2DBBC4BB3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Q7</accession>
    <name>C7Q7Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787543.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3343"/>
    <dbReference type="EnsemblBacteria" id="ACU72250">
        <property type="protein sequence ID" value="ACU72250"/>
        <property type="gene ID" value="Caci_3343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3343"/>
    <dbReference type="eggNOG" id="COG3871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134364_0_0_11"/>
    <dbReference type="OMA" id="ERHLCTL"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019920">
        <property type="entry name" value="F420-binding_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03618">
        <property type="entry name" value="Rv1155_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="13"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="15023" checksum="FFBBCF47EAED0475" modified="2009-10-13" version="1">MSDPVPTDSDGMAFWTERHICSLASVRPDGTPHLVPVGAVYDPSTGLARIITSGTSTKARRILRAGTLPVAVTQTDRGRWTTLEGVARVNQDPEAVADAERRYAARYGEPRPNPLRVVIEIEVRRVLGTVKVPLPGAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Y3</accession>
    <name>C7Q7Y3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5291"/>
    <dbReference type="EnsemblBacteria" id="ACU74150">
        <property type="protein sequence ID" value="ACU74150"/>
        <property type="gene ID" value="Caci_5291"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5291"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153642_0_0_11"/>
    <dbReference type="OMA" id="RNEYTIN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="13826" checksum="574D963A5D5A0C10" modified="2009-10-13" version="1">MQEKSLTFCSALRYDRDVAATAGKRDAWTLLTSHGHVLVEIARNPQARIRELSVAAGITERATAAIISDLVKAGYVARSRVGRRNHYSVNLDLGFRHAAQRDLRVGPFLALLAEQPLEGADAEQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q839</accession>
    <name>C7Q839_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793935.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5347"/>
    <dbReference type="EnsemblBacteria" id="ACU74206">
        <property type="protein sequence ID" value="ACU74206"/>
        <property type="gene ID" value="Caci_5347"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5347"/>
    <dbReference type="eggNOG" id="COG2321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059329_1_0_11"/>
    <dbReference type="OrthoDB" id="1175086at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007343">
        <property type="entry name" value="Uncharacterised_pept_Zn_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30168">
        <property type="entry name" value="PTHR30168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04228">
        <property type="entry name" value="Zn_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="33081" checksum="F5909301B2ABD62F" modified="2009-10-13" version="1">MRFDDDAQLDSDQVRDERGSGPARGGLGGGFGGGFGLPGGRGGLIGLILTLIAAAVGVPLALTEGSGTSSSSLSSSGSGNVTGTVGTGSLAAKCRTGADANASDDCRVVAVVNSVQNYWTGFFARNNQKYPPAQTVIFSGSTRTGCGSATSAVGPFYCPSDRTVYLDLGFWQELKTKFGARGGPFAQAYVLAHEYGHHVQNLTGALRNSQSSQQGANSGAVRVELQADCYAGLWAHYATTTKDANGRVLIKDLTKQDISDGLDAAAAVGDDRIQAEFHQRVTPETWTHGSAAQRQRWFLTGYQTGNFQSCDTFSGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q853</accession>
    <name>C7Q853_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793949.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5361"/>
    <dbReference type="EnsemblBacteria" id="ACU74220">
        <property type="protein sequence ID" value="ACU74220"/>
        <property type="gene ID" value="Caci_5361"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5361"/>
    <dbReference type="eggNOG" id="COG3315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="MNRATAW"/>
    <dbReference type="OrthoDB" id="1186918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30882" checksum="B49B36EA125F4A3A" modified="2009-10-13" version="1">MADHEGLGGPLPPLFDAPQPRRPAALDTDSPHVARLYDFLLGGKDHFRADRAAAELLLRANPYLRDTCREQRDFLRRALVRLATVGVRQFVDIGTGLPTMPSTHQIVRGVEATARVAYVDNDPIVLSHARVLLTDGGPGTAFVEGDLREPEALLRDPVLTALIDFNEPVAMIATGLLHFLLDHEQPAKHLRTLMDGCPPGSCLVLTHGATDLAVELARATAAAFRQSTIPCQARSRDEVLELLGDLQPLEPGLVPMAAWWNEGPVTKAVRERQIAYGVVARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q859</accession>
    <name>C7Q859_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74226">
        <property type="protein sequence ID" value="ACU74226"/>
        <property type="gene ID" value="Caci_5367"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5367"/>
    <dbReference type="eggNOG" id="ENOG5033EJR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141493_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019235">
        <property type="entry name" value="DUF2178_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09946">
        <property type="entry name" value="DUF2178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="16249" checksum="9E283E014217EADB" modified="2009-10-13" version="1">MSTDADRNAGGARDAENAGIASAPSSARQRGARRQSWIVPVTAAVLGAAFLAIYLGHHNVGMAVSGLLIMLGYAAVLVIGSRRSEAVSLLRGETGDERARSIEQRASALTLHVLALVLVGGYIVALIRGHESGTWAGLCAVLGGTYLLSTVVLTRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8F2</accession>
    <name>C7Q8F2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795868.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7311"/>
    <dbReference type="EnsemblBacteria" id="ACU76140">
        <property type="protein sequence ID" value="ACU76140"/>
        <property type="gene ID" value="Caci_7311"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7311"/>
    <dbReference type="HOGENOM" id="CLU_713080_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="43964" checksum="C49410A2C658C461" modified="2009-10-13" version="1">MDVRTLLKKLQLAVRSEPADTDIPFGRTQKLPDDLRVGDHDALHVGTDISRRIRNVVAALLSDLHYEHLKDGADAAVWDFVCHAAIERSKDHVAGFIQQHHQDLRVATVRFSVEYLTVTVPFEVFEVTFQPLPAEDTDEGQRFRLDAHCGSLAGVEVSGTDMERMVARGREHVEHALRVLRISMANVEQLNEGQLRFKLGQWYAIEGMGRGFHRYRDAPIPLELPKQPAELFANFALLPIRYDDRTEIGRQAKLALGWINSARLAIDPIHKVAFLFSALESMLGDKSAGLKAPMLMYFRTLLGQVVNDGFPSPNRLYEFYDEVRSNAVHGEEVPEFTTDEVNRLEWSIRSALVELLTLCDQHKLTKRSQVRKTLLATEHARPTYDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H1</accession>
    <name>C7Q8H1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV secretory pathway VirD4 components-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795887.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7330"/>
    <dbReference type="EnsemblBacteria" id="ACU76159">
        <property type="protein sequence ID" value="ACU76159"/>
        <property type="gene ID" value="Caci_7330"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7330"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013918_1_0_11"/>
    <dbReference type="OMA" id="GQHAFTA"/>
    <dbReference type="OrthoDB" id="859985at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="719" mass="77950" checksum="7787637D0B74B223" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8U5</accession>
    <name>C7Q8U5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785654.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1437"/>
    <dbReference type="ESTHER" id="catad-c7q8u5">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70360">
        <property type="protein sequence ID" value="ACU70360"/>
        <property type="gene ID" value="Caci_1437"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1437"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_16_1_11"/>
    <dbReference type="OMA" id="WYQYYFH"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="33629" checksum="1BBF080568B9AB7B" modified="2009-10-13" version="1">MTFTAVDHIATPVLDIAYKHAGDPEGIPVVLLHGFPYDVRAYDKVAAALVARGGYSVYAPYLRGFGKTRFLSETNMRSGQQGAIGQDLLDFIDALGLDRPIVGGYDWGGRAACIVAALWPARVRGLVTVDGYNVQNIAHSGEPSKPEWEATYWYQYYFQSERGRRGLERNREELCELLWRTWSPTWTKASAEFPASAPSLHNPDFVEVVIHSYRHRYNLVEGDPRYQAIEERLAFGTEISVPTVVLESGADGIGGAGFDASGDRELFTGRFEYRKVDGVGHNLPQEAPEAFADAVHLLGSAADEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q929</accession>
    <name>C7Q929_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787642.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3443"/>
    <dbReference type="EnsemblBacteria" id="ACU72349">
        <property type="protein sequence ID" value="ACU72349"/>
        <property type="gene ID" value="Caci_3443"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3443"/>
    <dbReference type="eggNOG" id="COG3239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059522_0_0_11"/>
    <dbReference type="OMA" id="HDYHHRY"/>
    <dbReference type="OrthoDB" id="1382098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="43055" checksum="AAD189B5C1939AF1" modified="2009-10-13" version="1" precursor="true">MTDVRATYLRFPAWTQHFWTWQTGKALPGQKPLLRHTWASYLTLTLALFLGGLAVSATAVAAEYPYWYLALLAGWFLTVCGARMMVLVIAHQALHRRFSGTAARDGFWGETVTVLSVFHTFREFKEEHFDNHHRREIFATEADPPVQFLEALGFRPEMSRDQLWRRAWIVFFSPAFYGRNAYGRLRSNIVNGRVRKLGVLIWLGGWLSVPFWAPHGGWVLLLAFVIPVILFAQLSALLDRLGEHEWLAPRVPEYGHRFYTAANTSARFCGAPVPARHTPLARQSAQWLRWSVATLCYHVPARLLVIVGDLPNHDYHHRYPSTPEWTTAAYARQRDIDSGRDGGPPYQEVWGVGAAIDRLFRSWEGSPTDEPTYSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q932</accession>
    <name>C7Q932_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MbtH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787645.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3446"/>
    <dbReference type="EnsemblBacteria" id="ACU72352">
        <property type="protein sequence ID" value="ACU72352"/>
        <property type="gene ID" value="Caci_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3446"/>
    <dbReference type="eggNOG" id="COG3251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181321_1_0_11"/>
    <dbReference type="OMA" id="QYSLWPG"/>
    <dbReference type="OrthoDB" id="2067093at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005153">
        <property type="entry name" value="MbtH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038020">
        <property type="entry name" value="MbtH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037407">
        <property type="entry name" value="MLP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38444">
        <property type="entry name" value="PTHR38444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03621">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00923">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160582">
        <property type="entry name" value="SSF160582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MbtH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="7185" checksum="3B0EA98195276E9B" modified="2009-10-13" version="1">MNPFDDPEGTFLVLVNDEEQHSLWPAHLDVPAGWRGVHGSDTREACLAYVEEHWTDLRPLSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C5</accession>
    <name>C7Q9C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5412"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74271">
        <property type="protein sequence ID" value="ACU74271"/>
        <property type="gene ID" value="Caci_5412"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5412"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_0_3_11"/>
    <dbReference type="OMA" id="RQAATWP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="5">
        <location>
            <begin position="71"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="4">
        <location>
            <begin position="190"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="38391" checksum="2726CA85E6E5C94D" modified="2009-10-13" version="1">MTATNPNRNPNRNPNRNPNRTPDPNPPAMRILLVRPESTGGIGVHVDSLTRALREAGHDVRTLVATGTGAIPAIRHAARQAHVDVVHAHGLRAGAAACLATRKRTVVTLHNAPSNRAGEMLMRLIAQRADAVLAASHDLVEAVTGNGAKNARFGPVVAPALPAPTLPTSQVRTELRNALGLATATADAADPRRLVLAVGRLAPQKDYATLLNALIILKNRLGPAHIPSVAIAGEGRERAALQATIDAHELPVVLLGHRADIADLLRAADVFVMCSTWEARPLALQEALRAGVPHVIATDVGGVAEVTAGYLPLIPPGDPEALSRALMDAASASRAAMPDWDALWPGPQEELAAVLAAYAEKPPNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I4</accession>
    <name>C7Q9I4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ordered locus">Caci_5471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5471"/>
    <dbReference type="EnsemblBacteria" id="ACU74330">
        <property type="protein sequence ID" value="ACU74330"/>
        <property type="gene ID" value="Caci_5471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5471"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_0_11"/>
    <dbReference type="OMA" id="PHLTPMI"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="344" mass="34558" checksum="568EEA64AAD6E278" modified="2009-10-13" version="1">MHMTYTAAVAGATGYAGGELLRLLLGHPDFQIGALTAGTSAGTRLGEHQPHLAPLADRVVADTTPETLAGHDVVFLALPHGQSAAIAEALGPDTLIVDCGADYRLADAGVWEKFYGSPHAGTWPYGLPELPGARAALTGAKRVAVPGCFPTVSTLALAPAVGAGLVEPDVVVVAATGTSGAGKSLKPNLLGSEIMGNVAAYNIGGVHRHSPEIAQNLGAVAGQAVTVSFTPLLVPMPRGILATCTAKVKPGVGEEQLRDAYLKAYGDEPFVTVLPQGQLPTTAAVLGANTVQIQVAFDEAAGRAVVVGAIDNLTKGTAGGALQCANLALGLPEPAGLSTVGIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9K0</accession>
    <name>C7Q9K0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_5487</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5487"/>
    <dbReference type="EnsemblBacteria" id="ACU74346">
        <property type="protein sequence ID" value="ACU74346"/>
        <property type="gene ID" value="Caci_5487"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5487"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_409221_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009839">
        <property type="entry name" value="SseB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07179">
        <property type="entry name" value="SseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982931" evidence="6">
        <location>
            <begin position="25"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="48"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="SseB" evidence="8">
        <location>
            <begin position="509"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="644"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="671" mass="68483" checksum="CAD54BBB3C5B69CD" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9N2</accession>
    <name>C7Q9N2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate protein domain protein TPP-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795929.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7374"/>
    <dbReference type="EnsemblBacteria" id="ACU76201">
        <property type="protein sequence ID" value="ACU76201"/>
        <property type="gene ID" value="Caci_7374"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7374"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_0_11"/>
    <dbReference type="OMA" id="YEATHEC"/>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="189"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="380"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="576" mass="61542" checksum="547E4568FA47F497" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9S3</accession>
    <name>C7Q9S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7416"/>
    <dbReference type="EnsemblBacteria" id="ACU76242">
        <property type="protein sequence ID" value="ACU76242"/>
        <property type="gene ID" value="Caci_7416"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7416"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LKYAHGS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="164"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="39881" checksum="0AAFBB89C501A751" modified="2009-10-13" version="1" precursor="true">MLAAGLAVLAFAPALSKVGAQIGDLPSRPADVVSVALALAQALPLAVRRRFPAAVLAVIGFAFAADQALGYPTTFASLGLYLALYSSGAHQDRLRRAVAVSATVGYSALALVLHHLGAPHGFGDYSVFYLVTTAAWLAGTVMRRLREQEIERRRLVAEAAGAAERARIARELHDVVTHHVTAMVVQADAAQFLLSSHPERVVAGLTSVSDTGRRALTELRYLLGVLEATGDGARPDRAPAQGTIADLVEQARAAGQPVEFSEIGEHRPRPVAVELAAYRVVQEALTNAMKHAGAARTNVLVRHHPRHMEVEVTTEGPVKEGAAASASPPRASELPGGGRGLAGLRERVRVLHGELEAGPRSDGGFAVRARIPFGPDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9T5</accession>
    <name>C7Q9T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795982.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7428"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76254">
        <property type="protein sequence ID" value="ACU76254"/>
        <property type="gene ID" value="Caci_7428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7428"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_14_4_11"/>
    <dbReference type="OMA" id="MHTVDHP"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="47"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="189"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="388" mass="40563" checksum="E10229776E12C772" modified="2009-10-13" version="1">MTSFGFLSTYPPTQCGLATFSAALVRHLTGQGTGDRAGVVRVVDAAQPAVYPDVVAQLVNGSPTGAARAAAVLNRFDVAVVQHEFGIYGGRDGEDVLRLVGELTVPAIVVLHTVLAAPTAHQRQVLERIADAAAAVVVMSRTAADRLREGYLVDTAKVSVIPHGALSSRRMSPPASFNPFAPPAPASAPRRPTVLTWGLLGPGKGIERAIAAFAGLGDLTPAPRYVIAGQTHPKVLARDGEAYRDSLRAQAEDLGIAADVEFDTEYRNPDVLMDLVRSADVVLLPYDSTEQVTSGVLIEAVAAGRPIVATRFPHAVELLEDGAGLLVAHEDVPAMTEALRAVLTQPALAASMTLASGRIAPDLAWTSVAESYRALAKSLLDAPITAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9U8</accession>
    <name>C7Q9U8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7442</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795992.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7442"/>
    <dbReference type="EnsemblBacteria" id="ACU76267">
        <property type="protein sequence ID" value="ACU76267"/>
        <property type="gene ID" value="Caci_7442"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7442"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="YCSEMAG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="121"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="45799" checksum="FA5F287B9A63238D" modified="2009-10-13" version="1">MDFRYTPAQQDLKRRAADYVKLLIQYEDQAEQARGALPKSIVRELTLAAMDAGVYAINMPVEWGGPGLSLLEQVIVEEEFGKATNCLWDIPWRPSNVLAYGTPEQREKYLLPIIRGEKFDAFAVTEPEAGSDPSSGVTVATRTAGGWLLNGEKWFVTCGDIADFLLVQADAIVEGAQGPEKLATLFFVDKNAPGLEMTRVPHFMHHAVNGHPEFTLTDVFVADEDVLGDVGEGYELTKEWFTDERLMIAARTVGAAERALSEARDWAVRRQAFGQPIAEFQLIQGMLADCAVDIAVNRAYTHQVAWEADQPDTDRKTLHAKASTAKLAASEAAGRVADRCVQIFGGRGYDSAFAVERIFRELRVDRIWEGTSEIQRVIIANELIKRGTRSLALPRPAAATDITAATAAPASATTNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC6</accession>
    <name>C7QAC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3519"/>
    <dbReference type="EnsemblBacteria" id="ACU72425">
        <property type="protein sequence ID" value="ACU72425"/>
        <property type="gene ID" value="Caci_3519"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3519"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001218_1_2_11"/>
    <dbReference type="OMA" id="PWELRLH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6531" evidence="3">
        <location>
            <begin position="365"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1508" mass="161297" checksum="A1C9F402ED754359" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL4</accession>
    <name>C7QAL4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3609"/>
    <dbReference type="EnsemblBacteria" id="ACU72513">
        <property type="protein sequence ID" value="ACU72513"/>
        <property type="gene ID" value="Caci_3609"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3609"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088936_0_0_11"/>
    <dbReference type="OMA" id="PVWRECA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="87"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30350" checksum="8C24886B9308482B" modified="2009-10-13" version="1">MIVLAGSTERRVPLSRELNVPDAVVDPGAHNRAAWDKLVQDGNEWSRPVSAEDVERARSGDWSIVLIGHEPVDRSWLPADLTGKDVLCLASGGGQQGPILAAAGARVTVFDNSPGQLGQDQMVAARDGLELRTVLGDMSDLSAFGEAAFDVVVHPVSNCFVPDVAPVWRECFRVLRPGGTLLAGFLNPDAYLFDDEALDERGELVVVHKLPYSDVTHYSAEERAAKFGADAALEYGHTLTDQIGGQLAAGFVLTGFAEAPHHSNASADYMSHYFATMAVKPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV5</accession>
    <name>C7QAV5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP/GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794157.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5569"/>
    <dbReference type="EnsemblBacteria" id="ACU74428">
        <property type="protein sequence ID" value="ACU74428"/>
        <property type="gene ID" value="Caci_5569"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5569"/>
    <dbReference type="eggNOG" id="COG0645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111135_0_0_11"/>
    <dbReference type="OMA" id="GTLVMPM"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="19445" checksum="211001854808B882" modified="2009-10-13" version="1">MIVWLNGTHGSGKSTTSPLVQQLIPDSRVFDAEKVGETLMDITPGLPETDNFQHWPPWRPLVVETARRVLDYTGGTLVIPMTVLVEQYWREISAGLADHGIPVRHFVLHADQDTLRGRIAGDMVLGPNSPFRLQYLEPYAEAARTWLHREAEVIDTTRLTPAEAALQIAEAVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBM4</accession>
    <name>C7QBM4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome bc1 complex cytochrome b subunit</fullName>
            <ecNumber evidence="2">7.1.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytochrome bc1 reductase complex subunit QcrB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785895.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1680"/>
    <dbReference type="EnsemblBacteria" id="ACU70601">
        <property type="protein sequence ID" value="ACU70601"/>
        <property type="gene ID" value="Caci_1680"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1680"/>
    <dbReference type="eggNOG" id="COG1290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031114_2_0_11"/>
    <dbReference type="OMA" id="WNYGPYD"/>
    <dbReference type="OrthoDB" id="262439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13631">
        <property type="entry name" value="Cytochrom_B_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="8">
        <location>
            <begin position="21"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="543" mass="60315" checksum="296E15B709C8B164" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS9</accession>
    <name>C7QBS9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792277.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3646"/>
    <dbReference type="EnsemblBacteria" id="ACU72548">
        <property type="protein sequence ID" value="ACU72548"/>
        <property type="gene ID" value="Caci_3646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3646"/>
    <dbReference type="eggNOG" id="ENOG50314EV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094601_1_0_11"/>
    <dbReference type="OMA" id="FRINTMF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21981" checksum="40B393EA45036AB1" modified="2009-10-13" version="1">MDAFSHIEAERLRVADALEGVAEHQWPLQSLSVGWSNHFTLAHLVGSSQVNFPKAMRAMAASGFNFGRMVNKLNVQAAQTPSAQLVTKLRELAPSHDHPPGPAVAQLLEVVVHGEDIAYPLGVRIDHDDAALVAAANYAKKEQMFVGVRKRIAGLRLQATDLDWSAGEGALVEGPLRSLVLAMCGRNAALDALSGPGVAVLRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCU0</accession>
    <name>C7QCU0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785944.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1729"/>
    <dbReference type="EnsemblBacteria" id="ACU70650">
        <property type="protein sequence ID" value="ACU70650"/>
        <property type="gene ID" value="Caci_1729"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1729"/>
    <dbReference type="eggNOG" id="COG0462">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_2_0_11"/>
    <dbReference type="OMA" id="HYAYARS"/>
    <dbReference type="OrthoDB" id="1011035at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="3">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="33769" checksum="698D5251F190305F" modified="2009-10-13" version="1">MRDIAVFSGSAHPTLAAEICAHLETPLSPVRVSRFANDCLEVQLQANCRERDVFLVQPLVAPVQEHLVELLLMCDAARGASAARITAVVPHYSYARSDKKDAPRISIGGRLVADLMVAAGANRVLAMTLHSPQVHGFFSVPVDHLNALRELALHFRDYDLSHTTVVSPDLGNAKEAAAFARLLGVPVAAGAKQRFAGDTVAISSVIGDVAGRDVIVLDDEIAKGSTVMELLERLRELGARSVRVACTHGLFAAGALKRLADHPDVEEIVCTNTVPIPSTEQTDTDKLTVLSIAPALAEAMRRIHNGESVSALFEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY1</accession>
    <name>C7QCY1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1770"/>
    <dbReference type="EnsemblBacteria" id="ACU70691">
        <property type="protein sequence ID" value="ACU70691"/>
        <property type="gene ID" value="Caci_1770"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1770"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="PYLAAWP"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="270" mass="29444" checksum="4ECE8B59D452CCB9" modified="2009-10-13" version="1">MLERHELDAFLTLAEQLHFGRTAELLTVSPARVSQTIAKLERRIGVRLFHRTSRRVELTAAGRELYAELRPAWTAITEAVARATEAGRGVTGTLRAAFVGAAGGQLLVGAAEAFGKSFPDCEVVVREAQFGDVGPWLANDEVDVVLSTRETDVPGTVQGATLVSEARMLAVALGHPFARRQTVSLADVARTTPVEAQATLQETLTLVGAGRGVAEVGAQTRRYYPRPDVVYVPISDAPPVRWCLLWHEDRETARVRAFDHVLDELVRSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD10</accession>
    <name>C7QD10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1799</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1799"/>
    <dbReference type="EnsemblBacteria" id="ACU70720">
        <property type="protein sequence ID" value="ACU70720"/>
        <property type="gene ID" value="Caci_1799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1799"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="PMPIAAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="2"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="452" mass="48173" checksum="6D76BB07B8D4722A" modified="2009-10-13" version="1">MYDLINPATGAVFRSLEMTSADGVDQAVARAREAFPAWRDVAPADRARLLRRFADLVDSHTEELARIEVENAGHTISNARWEAGNVRDVLTYYAAAPERLFGRQIPVAGGLDLTIAEPLGVVGVIVPWNFPMPIAAWGFAPALAAGNTVVLKPAETTPLTALRLAEIALEAGLPEGVLQVVPGFGPEAGARLVEHPDVRKIVFTGSSAVGRSIMARCAADVKRVTLELGGKSPNIVFADADIEKAAASAPYGVFDNAGQDCCARSRILVESSAYDEFLEHFLNACRGVVIGDLLDEKAEMGPLISATQKARVSGFVDRVPADRLAYQGEVPDTAGFWFPPTVVTGVSADDEIQCEEVFGPVVTVVPFSSEQQGIELANLTQYGLSGSIWTRDLSRALRVSRAVQAGNLSVNSNSSVRYSTPFGGYKQSGLGRELGPDALAAFTETKNVFIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD2</accession>
    <name>C7QDD2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-glucuronidase</fullName>
            <ecNumber evidence="4">3.2.1.139</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3824</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.139" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3824"/>
    <dbReference type="CAZy" id="GH67">
        <property type="family name" value="Glycoside Hydrolase Family 67"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72725">
        <property type="protein sequence ID" value="ACU72725"/>
        <property type="gene ID" value="Caci_3824"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3824"/>
    <dbReference type="eggNOG" id="COG3661">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007125_1_0_11"/>
    <dbReference type="OMA" id="DNNGWGQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046559">
        <property type="term" value="F:alpha-glucuronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037054">
        <property type="entry name" value="A-glucoronidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011099">
        <property type="entry name" value="Glyco_hydro_67_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011100">
        <property type="entry name" value="Glyco_hydro_67_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07477">
        <property type="entry name" value="Glyco_hydro_67C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07488">
        <property type="entry name" value="Glyco_hydro_67M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_67M" evidence="3">
        <location>
            <begin position="140"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_67C" evidence="2">
        <location>
            <begin position="463"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="695" mass="76177" checksum="AA4A55DD75B740A9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDH4</accession>
    <name>C7QDH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792496.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3879"/>
    <dbReference type="EnsemblBacteria" id="ACU72767">
        <property type="protein sequence ID" value="ACU72767"/>
        <property type="gene ID" value="Caci_3879"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3879"/>
    <dbReference type="eggNOG" id="ENOG5030GV3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896632_0_0_11"/>
    <dbReference type="OrthoDB" id="1196806at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="37380" checksum="A285665B9CB5088C" modified="2009-10-13" version="1">MTRQEPAETGQEFEGQWQKPPDVAGLLLPASDSGQARAPSHLFGVVSTALIQHSGALPLARSAEILRIVPQRVVTRIGNVQQTVRPVPLAWSAHRVAGIDSGVLGIPNRAILGTAVGRAVVYGGRIVQGSAWVAVVPMSTAGRRPWGEKLAAPGTAVVDDSTLRVLIDAPLSKPPDLGLTLIADRLVDDVQSSRRLDHVIAFRSAGDRLYWTAVLRDSELSKIHANLSETRGPVLHFTAPSDEPLDSIVRFCEDVARHKWLISTVALVSDRMARKHLDPAGRREVVQTVFDQLMHLWLPGSYLESRRNGYWTRTMNGIRLTQQWEVQVARLRELLEREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE21</accession>
    <name>C7QE21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7785"/>
    <dbReference type="EnsemblBacteria" id="ACU76609">
        <property type="protein sequence ID" value="ACU76609"/>
        <property type="gene ID" value="Caci_7785"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7785"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="KRTMIWC"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="232"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="44639" checksum="93BD9673D5EB6DB9" modified="2009-10-13" version="1">MTDTLTDSAPRRSLWRHRDFLLLWGGQSVSEIGSAITVLALPLAAVVLLDASTFQVGLLTAMSTVPFLLVALPAGALVDRAAKHRLMMWCDVGRLLLMASVPLATLPGLHLTYLHLLIVALAAGVLTVFFDVAYQSYLPVLLERGELVDGNGKLGTTQAFAQFAGPSLGGVLVGALGAARALIVDAASYGLSAVSLLLIRMPEPPPHPSHKERRIRDGIKEGLHFVVRHPILRKVVACTGTSNLFSSMLLAVEIPFMVRTLHLTPSGVGAVLSLAAVGGMVGGLVARPLAQRFGSARIIWLAPLVLGLPTFLAPLATPGWGALFYPAGLTFFGMMAVVYNVAQVSYRQAITPHALLGRMNASVRFIVWGTMPLGALLGGLVGTWLGLRPTLWIAVAGSYAAVAWVFFSPLRRMRDVPDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC6</accession>
    <name>C7QEC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1897</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786111.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1897"/>
    <dbReference type="EnsemblBacteria" id="ACU70817">
        <property type="protein sequence ID" value="ACU70817"/>
        <property type="gene ID" value="Caci_1897"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1897"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="LMLTRHA"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="21554" checksum="4F4947D6AD35D5D5" modified="2009-10-13" version="1">MIRVLLVDDETLLRTALASLLSLSGEIEIVAQAADGLTAVALAETCDPDVIVLDLEMPGIDGIETVRRIIAARPAQAVVMLTRHGRAGVLRMALAAGVRGFLLKSVDPTELERVIIHVHSGKRWIDAEVSAAAMTDDCPLTDRELDTLRLTTEGLSVREISTRLHLASGTIRNYLSSAMQKTGGSSRHAAARVARERGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGQ6</accession>
    <name>C7QGQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794665.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6080"/>
    <dbReference type="EnsemblBacteria" id="ACU74936">
        <property type="protein sequence ID" value="ACU74936"/>
        <property type="gene ID" value="Caci_6080"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6080"/>
    <dbReference type="eggNOG" id="ENOG5030PSG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082127_0_0_11"/>
    <dbReference type="OMA" id="RYGVAEY"/>
    <dbReference type="OrthoDB" id="1070315at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027860">
        <property type="entry name" value="DUF4429"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14472">
        <property type="entry name" value="DUF4429"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4429" evidence="2">
        <location>
            <begin position="11"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4429" evidence="2">
        <location>
            <begin position="145"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="1">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="31572" checksum="71CF1FB7AD3A2399" modified="2009-10-13" version="1">MAELIGKNGTWTFDGDVVRIVPGHDKDVSRLRAALGEITVPLAALTGVAFEAAGKKSKNGAGRIRLRLRVGADPLLQACDGRLDDDSDPYQLDVPPERGGVAEYFADEVRDALTVAQIPGEATDQYLLAPPAVPISANGQDGTGSFDGEMVRLEWGWLADGKKRSAGNRAWPLSALEAVEWRPAVGMDWGWIRFRVRGDAGIVSTNPRLDPNCLALWGTKKESGNSAVLAAAIVGRMTHPNAPAEVASAADGVAAAAGGADHDVLLRRLRELGDLYRDGVLTDEEFAAAKQAVLKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGT6</accession>
    <name>C7QGT6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794695.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6111"/>
    <dbReference type="MEROPS" id="S53.008"/>
    <dbReference type="EnsemblBacteria" id="ACU74966">
        <property type="protein sequence ID" value="ACU74966"/>
        <property type="gene ID" value="Caci_6111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6111"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_3_0_11"/>
    <dbReference type="OMA" id="IRTDVHE"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980963" evidence="4">
        <location>
            <begin position="32"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="5">
        <location>
            <begin position="89"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="423" mass="41883" checksum="93F9964CCE58C259" modified="2009-10-13" version="1" precursor="true">MSRTTPHRLIGVLGAAALAVGMVAAMAPANAATAAKSHPSNVKNVCGAAKPGFDRCYAEIRTDVHEPAHISRVAGTAGKAAAAATAPAGFGPADLHAAYNLPTTGGANQTVAIVDAGDDPTAEADLAVYRSTYGLPACTTANGCFTKVNQRGTASPLPSDIGWGVEEALDLDMVSAACPQCKILLVEGDDADSDDLGASVDTAVRLGATEVSNSYGGTESSATPGDAAHYTHPGTAIVASSGDSGYGIPSEPAVFASVVSVGGTSLTKDSSSRGWSESAWSSDGGAAGSGCSAWVDKPAWQTDANCPGRMVSDVSADADPNTGPAIYVTDTPDLEGLPSGWNIVGGTSASSPFIAGVIALAGNPGKYNNASAFYAPAAKAGLNDPVGGSTGLWVDCGGDYQCTGVAGYDGPTGMGSPNGLSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGZ2</accession>
    <name>C7QGZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796567.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8019"/>
    <dbReference type="EnsemblBacteria" id="ACU76842">
        <property type="protein sequence ID" value="ACU76842"/>
        <property type="gene ID" value="Caci_8019"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8019"/>
    <dbReference type="eggNOG" id="COG1399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100236_0_0_11"/>
    <dbReference type="OMA" id="RLDHRNP"/>
    <dbReference type="OrthoDB" id="1665714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="21535" checksum="AA26A46C93B00D9D" modified="2009-10-13" version="1">MPGTTPKKPAQPDPRSPYVVDTQDFGRRPGSMRKLHETVPAPESIGDKDGVASVPAGSDVDLDARLEAVVEGVLATGTVSAAVAGECVRCLDPLDLDVEAEFQELFFFPGEDTGGDEDAVFLVNDLLDLEPIVHDAVVLALPSAPLCRDDCQGLCPECGVNLNDDPEHSHETADPRWAALADLKDQVASNSGTAPVAPPARDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN9</accession>
    <name>C7QHN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71064">
        <property type="protein sequence ID" value="ACU71064"/>
        <property type="gene ID" value="Caci_2145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2145"/>
    <dbReference type="HOGENOM" id="CLU_3181614_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="46" mass="4414" checksum="DBFE2A8FC1CB0057" modified="2009-10-13" version="1" precursor="true">MARGHRAALSSPVCAVGMVGMVCAVGVVSAVGMVGGGVMPREGVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI28</accession>
    <name>C7QI28_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4209</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4209"/>
    <dbReference type="EnsemblBacteria" id="ACU73073">
        <property type="protein sequence ID" value="ACU73073"/>
        <property type="gene ID" value="Caci_4209"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4209"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_0_1_11"/>
    <dbReference type="OMA" id="HAILNHE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="30588" checksum="4FACF4E2D83E10D1" modified="2009-10-13" version="1">MSDRPDRITVRFTVLGPVSIDDGAQTVILPTAKPVSLLAAMLLRPNRVVPVDYLQNAVWGENAADTTKATLQAYILRLRRIFRKFGADDTIIQTLPGGYRLPVTAATLDLAEFRELTAAAGSAEQPEAELRHLRRALALWQGGPLANVQSEALHRDEVPVLEEEWLRTAERRFDVELGLGRHRDILADLRSATRAYPACERFREQLMEALYRTGRQADALWEYRSIKDYLGEELGVFPGRPLQQLELAILRGEELTPRPWAESRIRIGEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE3</accession>
    <name>C7QIE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6166"/>
    <dbReference type="EnsemblBacteria" id="ACU75020">
        <property type="protein sequence ID" value="ACU75020"/>
        <property type="gene ID" value="Caci_6166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6166"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="CLHIVRE"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="258"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="362" mass="38523" checksum="12E9DD6404F3F3AA" modified="2009-10-13" version="1">MVETMEKVEDTGGRASRNGDVWPAAEPGRRPRDAADKVRKAHKAAGKHTVAVAVTEGAPIFEISIPVEVFGRIRPGMPELGYDVRICNPESGPVSSSGFTALAGDSYAALLTADTVIVPAVGDIYTEPAADLVAAVRQAHANGARVASLCSGAFVLAAAGLLDGRRATTHWYYAQEFRKRFPAVDLDPAVLYIDDGDVLTSAGTTAGIDLCVAIVAADHGADVANTLSRRLVAPTHRSGGQAQYVDTPAPLARRDNLGPLLDWMRTHLAETLTVADLARHANVAERTLIRRFHTAVGTTPGKWLTEQRVLHARRLLETTDLPVDRVASAAGLGGAANLRHHFTEVVGVAPSDYRRAFRQPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIF1</accession>
    <name>C7QIF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitrite reductase (NAD(P)H), small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794757.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6174"/>
    <dbReference type="EnsemblBacteria" id="ACU75028">
        <property type="protein sequence ID" value="ACU75028"/>
        <property type="gene ID" value="Caci_6174"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6174"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_3_0_11"/>
    <dbReference type="OMA" id="AAPLYKQ"/>
    <dbReference type="OrthoDB" id="1681886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03529">
        <property type="entry name" value="Rieske_NirD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017881">
        <property type="entry name" value="NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40562">
        <property type="entry name" value="PTHR40562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02378">
        <property type="entry name" value="nirD_assim_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="17"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="14756" checksum="F15CF57F2405DBEA" modified="2009-10-13" version="1">MTTVELTREEVRADAWTAVCKYTDLEPGRGVAALVADEPVAVFRLSDGSLYAVGNVDPFCGASVISRGITGMRGDGTATVASPMYKDVFDLATGVALDTPEVRLPVFAVRRHRGVVWVAPDVTSEAGLDAELLTEATLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ39</accession>
    <name>C7QJ39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0228"/>
    <dbReference type="EnsemblBacteria" id="ACU69181">
        <property type="protein sequence ID" value="ACU69181"/>
        <property type="gene ID" value="Caci_0228"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0228"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OMA" id="CWQLAFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="770" mass="83257" checksum="32B3F6AA0EA486DD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG1</accession>
    <name>C7QJG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FeS assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786477.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2266"/>
    <dbReference type="EnsemblBacteria" id="ACU71184">
        <property type="protein sequence ID" value="ACU71184"/>
        <property type="gene ID" value="Caci_2266"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2266"/>
    <dbReference type="eggNOG" id="COG0396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_48_1_11"/>
    <dbReference type="OMA" id="MAMLEPK"/>
    <dbReference type="OrthoDB" id="1214676at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27347" checksum="94E946E67BA61695" modified="2009-10-13" version="1">MATLEIKDLHVTVEGEGGPREILRGVNLTVKEGETHAIMGPNGSGKSTLAYSIAGHPKYTITSGTVTLDGEDVLAMTVDERARAGMFLAMQYPVEIPGVTVSNFLRTAATAIRGEAPKLRTWVKEVNGAMEAIQMDKAMAERNVNEGFSGGEKKRHEILQMELLKPKIAILDETDSGLDVDALKSVSEGVNRVRESGEVGTLLITHYTRILRYIKPDYVHVFSDGRIVESGGPELADKLESEGYQAYVETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJN1</accession>
    <name>C7QJN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative thiol-disulphide oxidoreductase DCC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786547.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2336"/>
    <dbReference type="EnsemblBacteria" id="ACU71254">
        <property type="protein sequence ID" value="ACU71254"/>
        <property type="gene ID" value="Caci_2336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2336"/>
    <dbReference type="eggNOG" id="COG3011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086500_5_1_11"/>
    <dbReference type="OMA" id="GDCAFCT"/>
    <dbReference type="OrthoDB" id="2019103at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14342" checksum="F28DAE4330A41229" modified="2009-10-13" version="1">MNEGSFPKPVLIFDGDCAFCTRSVNVFKRLPIDAEVTAYQFTNLELYGTTEERATHEVLWVDPTGRIYGGAQAIARLLVSAGGIYAAAGWALRTPPIRWIAAAGYRLIANNRQRMPGGTAACALPPAARSGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJV9</accession>
    <name>C7QJV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4333"/>
    <dbReference type="EnsemblBacteria" id="ACU73197">
        <property type="protein sequence ID" value="ACU73197"/>
        <property type="gene ID" value="Caci_4333"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4333"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_0_11"/>
    <dbReference type="OMA" id="AHWFWSD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Reductase_C" evidence="2">
        <location>
            <begin position="319"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="411" mass="42839" checksum="FC9D7A76F31441CF" modified="2009-10-13" version="1" precursor="true">MAVIGAGLAAVSLCAALRAGGFTGRLTVVGDEPCHPYDRPPLSKQFLAGERDAAEIALQPPEWYPRERIDLRAGVAVAAFDADTGRVNLADGTTLLADAIVLATGGRARPLTVPGGEAATVLRTRADAEALRDRLAPGVRVLIVGAGLIGAEVAATATHHGCQVTLVDPSPLPMERAIGPHAARALHAQHAAHGVTVVCGGVTAIEAGQAVLTTGQSVPADVVVAGIGIVPNVELAEAAGLDVDNGVLVDAGMQTSVPGVYAIGDIARIGGAVNHGQAVHDGPVHERYRAEHWDNARRTAETAARTILGQPPEAPRAPWFWTDRYGTHLEMTGLYDAAAETVPRGAVEAGDGTVFYLRDGRCVGAVSLNRPLDIRAAQRFIDRDTPVEAAFLADERSDLRRLLMPKVHCPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW0</accession>
    <name>C7QJW0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine synthase vitamin-B12 independent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792927.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4334"/>
    <dbReference type="EnsemblBacteria" id="ACU73198">
        <property type="protein sequence ID" value="ACU73198"/>
        <property type="gene ID" value="Caci_4334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4334"/>
    <dbReference type="eggNOG" id="COG0620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_744069_0_0_11"/>
    <dbReference type="OMA" id="NDPRNPW"/>
    <dbReference type="OrthoDB" id="577156at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Meth_synt_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="354" mass="37881" checksum="72A552122D70CE0E" modified="2009-10-13" version="1">MTIPTENIGSIPRSPELLNALTSHAQGSLPDSALAELQDQAVADTIRRLEEAGCPVLTDGEQSKPSFATYPIAGSTALDPDGAIIPFADGHQRQLPALTAGPFRYQTHADTYLRAAQQHTAKPVKQAVIAPSALSLLYPANGIEGYSQADFLTDLADQAEADIRGCLDAGAHVVQLDFTEGRLSLKLDPSGGLLKQFIAVNNQVLDRFTDAERARIGVHTCPGGDMDSTHSLDVDYADLLPELFQLRAGNFYLQMASEPDPERVLSIASEHVRPDVRVFVGVIDPIDPQVETAEQVRDRVLAAARHIPVDRLGTCDDCGFSPFADDTSTSRETAFAKIAARVAGTAMAAEQLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB0</accession>
    <name>C7QKB0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794913.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6330"/>
    <dbReference type="EnsemblBacteria" id="ACU75184">
        <property type="protein sequence ID" value="ACU75184"/>
        <property type="gene ID" value="Caci_6330"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6330"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_626562_0_0_11"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="80"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="45592" checksum="E7D334E51543F18C" modified="2009-10-13" version="1">MTTTTPTPAPIDVSRVTPTPNAPALAPIDLAPPIPTASAPAPALAPVDLPRPIPTAPAPIDLSQPVFGAAASFPSSLDPARALAEAAPALAAHLSDFHRHPAGLPDLRAAVAERYTRRGVPTTPDHIVVTSSPQAALALAIGLFCAPEDRVLVENPTHPDTLAVLRSCAVRPVPIPLGGNGITPADLPGRFVHTAARLAHFSAGYQNPTGHLPSAEVRLAAAESARRSGTWLIADETAIEPVLDGVAPEPFTLGVPRAAAERIVTIGAPSQTHGLALRVGWLRATPRTAAALARHQADAGLGASALDQILTTNLLHQADADLPAHRAQLRERRAALESALTRLAPEWSWRHPAGGLTLWVDLGRPAAAALTTHAANAGVHITPGSRFTLDPGAHDHHIPLPFTLPAPALTEAACRLATAWHQTLSTPRSPDRHMWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR2</accession>
    <name>C7QKR2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1713 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8338"/>
    <dbReference type="EnsemblBacteria" id="ACU77161">
        <property type="protein sequence ID" value="ACU77161"/>
        <property type="gene ID" value="Caci_8338"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8338"/>
    <dbReference type="HOGENOM" id="CLU_209136_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="COX24_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08213">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1713" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="33" mass="4159" checksum="425DFEB2A26371E7" modified="2009-10-13" version="1">MGSVIKKRRKRMAKKKHRKLLKKTRIQRRNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB2</accession>
    <name>C7PVB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784563.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0315"/>
    <dbReference type="EnsemblBacteria" id="ACU69268">
        <property type="protein sequence ID" value="ACU69268"/>
        <property type="gene ID" value="Caci_0315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0315"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103718_0_0_11"/>
    <dbReference type="OrthoDB" id="1951208at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18921" checksum="ABDD52BECFCEA79D" modified="2009-10-13" version="1">MGLDFRTDPETLREIVDDPAALAARIHTLAALDMDEHPEARSEYATLLRIAGRLDDAALEAELTLAAADLAGDLRRMVRATLLVGHVRQYRGEWDQADTMFHRAEKLALYLKDDRLVAAAAHHSGRSFYDQGKHVEAALRFRLALEIDTRIGSPKVSAVWEAFEAAMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD2</accession>
    <name>C7PVD2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsR</name>
        <name evidence="6" type="ordered locus">Caci_0335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784583.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0335"/>
    <dbReference type="EnsemblBacteria" id="ACU69288">
        <property type="protein sequence ID" value="ACU69288"/>
        <property type="gene ID" value="Caci_0335"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0335"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_2_2_11"/>
    <dbReference type="OMA" id="CKDKATY"/>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="8957" checksum="A8061FD59B74EF03" modified="2009-10-13" version="1">MPKAPLRKPKKKVCGFCKDKVAYVDYKDTTLLRKFISDRGKIRARRVTGNCTQHQRDVAVAVKNSREMALLPYTSTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVE5</accession>
    <name>C7PVE5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784596.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0348"/>
    <dbReference type="EnsemblBacteria" id="ACU69301">
        <property type="protein sequence ID" value="ACU69301"/>
        <property type="gene ID" value="Caci_0348"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0348"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_336413_0_0_11"/>
    <dbReference type="OrthoDB" id="1128326at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982602" evidence="1">
        <location>
            <begin position="33"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="847" mass="88878" checksum="085B15197BA0D217" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI2</accession>
    <name>C7PVI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate dehydrogenase or fumarate reductase, flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784633.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0385"/>
    <dbReference type="EnsemblBacteria" id="ACU69338">
        <property type="protein sequence ID" value="ACU69338"/>
        <property type="gene ID" value="Caci_0385"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0385"/>
    <dbReference type="eggNOG" id="COG1053">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014312_7_0_11"/>
    <dbReference type="OMA" id="WRRIKVP"/>
    <dbReference type="OrthoDB" id="153138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033765">
        <property type="term" value="F:steroid dehydrogenase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="47"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="514"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="649" mass="71797" checksum="3CC3D850879DE3E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT0</accession>
    <name>C7PVT0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ordered locus">Caci_2404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786615.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2404"/>
    <dbReference type="EnsemblBacteria" id="ACU71322">
        <property type="protein sequence ID" value="ACU71322"/>
        <property type="gene ID" value="Caci_2404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2404"/>
    <dbReference type="eggNOG" id="COG0505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035901_2_1_11"/>
    <dbReference type="OMA" id="CFNTGMT"/>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="392" mass="42559" checksum="7AE1CFBA268D9E34" modified="2009-10-13" version="1">MNNRPPAILVLEDGRTFRGEAYGALGETYGEAVFTTGMTGYQETLTDPSYHRQVVVMTAPHIGNTGMNDEDPESRQIWVAGYVVRDPSRVASNWRSQRTLDDELAAQGVVGISGVDTRAITRHLRERGAMRCGVFSGDAARQDTETLVGKVAASPAMAGADLVGDVSTKQGYVVEPVGEHRFTVAAYDLGIKSMTPHRMAERGARVHVLSASATLEDVLALEPDGFFMSNGPGDPETTEETMVPIVQAVLDRRIPVFGICFGNQILGRAFGFGTYKLKYGHRGINQPVQDRATGKVEVTAHNHGFAVAAPLDKITDTKYGRVEVSHVCLNDDVVEGLRALDVPAFSVQYHPEAAAGPHDAAYLFDRFVGLMREHQHSTDLMAESKNTQKSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW11</accession>
    <name>C7PW11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine racemase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786696.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2485"/>
    <dbReference type="EnsemblBacteria" id="ACU71403">
        <property type="protein sequence ID" value="ACU71403"/>
        <property type="gene ID" value="Caci_2485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2485"/>
    <dbReference type="eggNOG" id="COG3616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_3_0_11"/>
    <dbReference type="OMA" id="SHPCSAF"/>
    <dbReference type="OrthoDB" id="1512472at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="306"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="44725" checksum="0F9ED858A912224C" modified="2009-10-13" version="1">MTASDLLDASFKGLPLHAAVTLDDLGSQGWNIRRGDTSTPVAVLRDAALDANLDVMRRFCATAGVSIAPHAKTTMSPQLIARQLAAGVWGLTAALPAQVRMLWSFGACRVLMANELTDPAALRWLARELAAHPERELLCYVDSLDGVRLAEQAFAEADTVLPVLIELGHAAGRTGVRDRETALAVAEAAAAAPHLAVAGVAGYEGTIGHDRTPETIARVDAFLTDLRDLAAALADRGLFAPDREPIASAGGSSFFERVAQILGPLTADGIRVVLRSGCYLTHDNGQYATLTPSTRPEWTLPPFQAALEVWTRVVSRPEPGLALLNAGRRDLSHDAGLPIPLTAWRDTTDTAIDLDEGAHISALSDQHTFLRIDPDSPLAVGDLVALGVSHPCMTLDRWRLFLLVNEDYDVIGGARTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW37</accession>
    <name>C7PW37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793014.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4421"/>
    <dbReference type="EnsemblBacteria" id="ACU73285">
        <property type="protein sequence ID" value="ACU73285"/>
        <property type="gene ID" value="Caci_4421"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4421"/>
    <dbReference type="HOGENOM" id="CLU_1324450_0_0_11"/>
    <dbReference type="OrthoDB" id="2172291at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980402" evidence="1">
        <location>
            <begin position="39"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="21156" checksum="10B2E31671363A61" modified="2009-10-13" version="1" precursor="true">MTGLRLRTPRTSRTRRTAAIAFAATGILLAPSAAVASAASGKHHAEHYAGHYAENHTVHTTRTSTNNSQQLPVQTNNGYNAACGPAADVEAMSMALGLVGIGNVALYTGAGRTGTGCDVITGTGLPIGTDFQIMGMTAANVDNRSDEPVAVYSDTTDNLDAVVPAGTDSDITPVDVNFAAYPQGSTPPPDDRGLIPAAVFQFPTGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW40</accession>
    <name>C7PW40_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative hydro-lyase Caci_4424</fullName>
            <ecNumber evidence="3">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4424</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-glutamate cyclase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793017.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4424"/>
    <dbReference type="EnsemblBacteria" id="ACU73288">
        <property type="protein sequence ID" value="ACU73288"/>
        <property type="gene ID" value="Caci_4424"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4424"/>
    <dbReference type="eggNOG" id="COG4336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059759_0_0_11"/>
    <dbReference type="OMA" id="NVPMYKT"/>
    <dbReference type="OrthoDB" id="1432388at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01830">
        <property type="entry name" value="Hydro_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009906">
        <property type="entry name" value="D-Glu_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038021">
        <property type="entry name" value="Putative_hydro-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016938">
        <property type="entry name" value="UPF0317"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07286">
        <property type="entry name" value="DUF1445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029755">
        <property type="entry name" value="UCP029755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160920">
        <property type="entry name" value="SSF160920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="27537" checksum="1D7C8212989772A4" modified="2009-10-13" version="1">MPETAAEVRAGFRSGVSGPTSGLAPGFRQANLLVVPADWAYDVLLFTHRNPDPCPVLDVTDTGSRHTPLAHDADLRTDLPLYRVWRDGRLVDEPTDITDVWREDSVTFLTGCSFTFDSALTSAGLPWRYPGRNVAMYVTNRECRPAGRFHGPLVVSMRPVPSALIGTAFRITTLMPTSHGAPIHLGDPGELGIRDLSKPDFGDAADIQPGDLPMFWACGVTLQAAVVASRPPFAITHAPGHMFITDVREPQVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD5</accession>
    <name>C7PWD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793112.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4520"/>
    <dbReference type="EnsemblBacteria" id="ACU73383">
        <property type="protein sequence ID" value="ACU73383"/>
        <property type="gene ID" value="Caci_4520"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4520"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="TDITMTI"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="92"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32462" checksum="E8DE5D471662020B" modified="2009-10-13" version="1">MTATVNLAPAGLKPRTRHPAWAAFRRAVTRKPGRLAGLIIIVFFILLAICGPWFYGSLSVDPNELYAPPSAKHWLGTDFAGSDVLQEVVTGARYVLATAALSALFTSLFGVTVGLVAGYQRGMTDSVLMRLTDFVLTIPGLPLLIILSTVWSFGSPWEMGLVLGITGWGGVARAVRSQALSLRERGFLEAARGLGLSRRHIIVKEMLPNIAPYAAMQLMLSVIGFIGAEVGLFFLGLVPFSSTNWGVMLNQAVFSGGAMETSSALIYLLAPLVCILLLTLGIVLFLDAIDELFNPRLRERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWF8</accession>
    <name>C7PWF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6384"/>
    <dbReference type="EnsemblBacteria" id="ACU75238">
        <property type="protein sequence ID" value="ACU75238"/>
        <property type="gene ID" value="Caci_6384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6384"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_11"/>
    <dbReference type="OMA" id="IAPSTWI"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="10"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="48209" checksum="1A3A4F7756FC79EB" modified="2009-10-13" version="1">MPEISGGRAVVLGASMAGLMAARVLREKYERVTVVERDVLPAGPEHRRGVPQSRHLHVLLARGTSIIEELFPGFVAEAVAAGATPADALARTRLLVSGYRLLQTDVGLQTVLAGRPLVEHIVRGRVRALDGVDFLDGHDVVSLAATADGRRVTGVRVQSDGGTEEMLEADLVLDATGRGSRSPVWLEQLGHGRPEVDKVQVGLSYATLTYRLPDGAMGKDQLMLNNATPGHQRAAVLSEQENGLFRLTMAGMLGDRPPLDRKGFDAFAASLRFPDIFEAVRDGEALHDPVGFQYPANIRHRYERMRSFPEGFLILGDAICSFNPVYGQGMTSAAMQAEALRGVLADDRGPTWKRHFRAMATAVDPAWQISAGGDLVFPGVVGHRTPLIRMINAYLPRVHAAAAEDVEISTRFIRVADLVDRPEALVRPATALRVLGRRRAKPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWU9</accession>
    <name>C7PWU9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ordered locus">Caci_8383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796931.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8383"/>
    <dbReference type="EnsemblBacteria" id="ACU77206">
        <property type="protein sequence ID" value="ACU77206"/>
        <property type="gene ID" value="Caci_8383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8383"/>
    <dbReference type="eggNOG" id="COG0414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_0_2_11"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="OrthoDB" id="1661843at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="184"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31144" checksum="7BF45C3821831A17" modified="2009-10-13" version="1">MTALVHTRAELQPFLDGFANGKRGVVMTMGALHEGHLELFKQARHDCDLVVATIFVNPLQFGPNEDFDRYPRTLDDDLKLCAEAGVDVVYAPAVEEVYPGGQPIVKVTPGPMGETLEGAFRPGFFTGVLTIVNKLLNLTDPDKAFFGQKDAQQLALVRRMVLDLNMPVEIIGVPTVRDEDGLAKSSRNRYLSSEERATALTLSRALFAGQEKATEGADAVRDAANAVLERTTATGELTVDYLALVDPRDFSEVPPAFTGQAVLAVAARAGTTRLIDNLPLTLTPHGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX18</accession>
    <name>C7PX18_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797000.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8452"/>
    <dbReference type="EnsemblBacteria" id="ACU77275">
        <property type="protein sequence ID" value="ACU77275"/>
        <property type="gene ID" value="Caci_8452"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8452"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="CTHIADI"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="12"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="297"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="515"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="333"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="608" mass="66994" checksum="95052812D030AD4A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX27</accession>
    <name>C7PX27_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797009.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8461"/>
    <dbReference type="EnsemblBacteria" id="ACU77284">
        <property type="protein sequence ID" value="ACU77284"/>
        <property type="gene ID" value="Caci_8461"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8461"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_0_0_11"/>
    <dbReference type="OMA" id="DILIMNF"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="40499" checksum="742053D1F615B5F4" modified="2009-10-13" version="1">MVTGMNGESAALPGLLVADFSRVLAGPYATMLLADLGADVVKVERPSSGDDTRAWGPPFAPDGSATYFQGVNRNKRSVALDLRSPRDAALARELIRRADVVVENFLPGTMERLGLGYEQMREANPGLVYCSITGFGDGAGAALPGYDLLAQAVGGLMSVTGEPGQPTKAGVALVDVITGMHAAFGILAALRHRDATGEGQRVSVSLLTSLLSGLVNHASAYLVAGVVPQAMGNRHPSIAPYEVFDAADRPLVIAAGNDRQFHSLCTALGAPELADDPRFATNTSRVAHREALIEELNRRLATKPAEEWFTALNEAGVPCGPINDVGDAFALAERLGLNAAVDVGGTRQTAHPVRFSTTPAAYFAPPPALDADGSAIREWLAQPSTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX62</accession>
    <name>C7PX62_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784708.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0461"/>
    <dbReference type="EnsemblBacteria" id="ACU69413">
        <property type="protein sequence ID" value="ACU69413"/>
        <property type="gene ID" value="Caci_0461"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0461"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="TVGSNNW"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="23"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="37991" checksum="69B1CD7F4E14789F" modified="2009-10-13" version="1" precursor="true">MAPRRSRNGVDLTAPTTASTTTTTIAAVAEEVGVSVATVSKVLNGRSDVAAQTRAKVEESLERHQYRRRAKKKQTGTGQVDLVFHELDSAWAMEIIRGVEAVTEPDGVDVVLSQLGGAHHPPQHWLDAVLARRPLGVLFVLCSPTKVQQERLRRQDIPFVVVDTDSATTASVPTVGSNNWNGGLVATRHLLELGHRRIGIISGPKDVLCSRARLAGFRAAHEEADVEVDPDLVRYGTFYLDAGYEHGMALLDRPDRPTAVFAGSDMQALGVLRAARQLGIDVPRGLSVIGYDNLEVAAWTDPALTTIDQPIRDMAGTATRMVLDLAHGQDPSSSRIDLVTALVVRESTAPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU6</accession>
    <name>C7PXU6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793135.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4543"/>
    <dbReference type="EnsemblBacteria" id="ACU73406">
        <property type="protein sequence ID" value="ACU73406"/>
        <property type="gene ID" value="Caci_4543"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4543"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_0_1_11"/>
    <dbReference type="OMA" id="DFAFPAV"/>
    <dbReference type="OrthoDB" id="1866750at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="23581" checksum="EBF8BA8A291E0CB6" modified="2009-10-13" version="1" precursor="true">MRSMWRTMDRDLLRGIAVMCASVGLIGVSYGATAVAAGLPIWLPVLTGFLVLAASSELLFVGVIAAGGDPFAGALAGLLVNARHIPYGLAVPDVIESGWRRIPSTHLLNDETVVLALSQDDLPRKRAAYWLCGLGIVAVWPLCALAGGLLGALVHNTDALGLDAMFPAVILALILPALRDRHTLRAALVGGAVAMAAFAFLPVGLPELLALVGVPFAGGLRHERSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU9</accession>
    <name>C7PXU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4546</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4546"/>
    <dbReference type="EnsemblBacteria" id="ACU73409">
        <property type="protein sequence ID" value="ACU73409"/>
        <property type="gene ID" value="Caci_4546"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4546"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_12_0_11"/>
    <dbReference type="OMA" id="CTEPWTW"/>
    <dbReference type="OrthoDB" id="1213908at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_2" evidence="3">
        <location>
            <begin position="124"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="38599" checksum="AA7A729CD2E0E960" modified="2009-10-13" version="1">MTIANPPSPQFSPAPSSPQSAMRLRELIFGAACAAAVRAAASLEVADALGEEPMTVEDLAKAVHAEPGPLRRLLRTLTCYGVFTDAGEDRYAHTDMSWQLRKESPNSLHYIALWCTEPWTWQLWPHLDEAVRTGRNIFPDVYGKEFFTYLHEDATASAEVFDKAMTHSSRQSAADLVGFLNLEGITSVVDIGGGQGHVLASLLEKHPEIHGTLIDLPQVIARADPRLHEAGTLSPRARLIATDCRTEVPVQADLYIIKNILEWDTDSTRRTLRNVVEAAPPGARVVVVENLVDDTPSMRFTTAMDLLLLLNVGGAKHSRASLQTLLTEAGLRVDEVRPVNPYLHAFECVVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY37</accession>
    <name>C7PY37_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4636"/>
    <dbReference type="EnsemblBacteria" id="ACU73497">
        <property type="protein sequence ID" value="ACU73497"/>
        <property type="gene ID" value="Caci_4636"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4636"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_0_1_11"/>
    <dbReference type="OMA" id="LGHYFGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="354" mass="37949" checksum="B6E27ADAF8541D65" modified="2009-10-13" version="1">MQQSALEGALESAAFLTEAELTAQLVGDARQIRVLTGDRPTGPLHLGHYLGSLRNRVRLQDAGADMFVLVADYQVITDRDASSSIADFALGLVADYLAVGLDPARSTVFAHSAVPAVNQLLLPLMSLISVPELERNPTTKAEAAASGRPALSALMLTYPVHQAADILFCRSDLVPVGKDQLPHLEVARTVARRFNTRYAPVFTEPRALISDAPSVLGSDGHKMSKSHSNTIPLQATADQTAALIKGFKTDTDRHIAFDPEHRPEVSNLLLITALCRGEDPVQVAEQIGAGGASALKRAATEAVNEHLAPIRARRLELAAERGYLSAILRRGAERATAEAEATLTRVREAMGMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY60</accession>
    <name>C7PY60_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_6500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6500"/>
    <dbReference type="EnsemblBacteria" id="ACU75350">
        <property type="protein sequence ID" value="ACU75350"/>
        <property type="gene ID" value="Caci_6500"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6500"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_11"/>
    <dbReference type="OMA" id="AISHECT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="5"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="124"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="507"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU75350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="589" mass="62834" checksum="B12A4C58E77F7A45" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYB7</accession>
    <name>C7PYB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6561"/>
    <dbReference type="EnsemblBacteria" id="ACU75407">
        <property type="protein sequence ID" value="ACU75407"/>
        <property type="gene ID" value="Caci_6561"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6561"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_11"/>
    <dbReference type="OMA" id="IADISIM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="24620" checksum="91D0894DCCC7097B" modified="2009-10-13" version="1">MSAVDVNGKVMIITGASAGIGEATARAAARAGATVVLAARRRARLDALAAEIGGDTLAVQTDMRDPAQVRRLVETAVERFGRVDVLVNNAGQGLHVPIEQITIEDLAAVVELNVYGALVAMQAVIPLMREAGGGCVINVSSGTTRMPAPRGAAGYAATKCALNMLSKAARAELAPDGIVVSTIYPFVTATEFHSTLRAGSGPAGRSGVEPDSAEKVADEILALIRSGEPEAVLIPEGLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYJ6</accession>
    <name>C7PYJ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797043.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8495"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77318">
        <property type="protein sequence ID" value="ACU77318"/>
        <property type="gene ID" value="Caci_8495"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8495"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_0_2_11"/>
    <dbReference type="OMA" id="IPCYNYA"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="39082" checksum="376D7271DCA27C13" modified="2009-10-13" version="1">MGSVSVVIPCYRYGHFLADCVRSVLDEQPGVDVRVLIIDDASPDDSADKARELAAADPRISVAVHEANKGHIATYNEGLLEWADADYSVLLSADDRLTPGALVRATALLDAHPAVGFVYGHPLTFQDGEPLPPARGADWQSGQWAVRPGLWWLRRRFRTAEGCITSPEVVIRTSVQKRIGGYDPALPHSGDIEMWMRAASVAGVGHIRGADQAYYRRHGANMSTVDFGGQLDDLHQRRAAFESVLVKCGDALPAADTWAADMRRKLARQALRRAVRAYDKGLTNTVPVAELIAFAEDCWPDYRRLPEYAGLRVRKAVGERAMPYLRPLVVSAAVNRGREWMWWQSWRRRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN1</accession>
    <name>C7PYN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797078.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8530"/>
    <dbReference type="EnsemblBacteria" id="ACU77353">
        <property type="protein sequence ID" value="ACU77353"/>
        <property type="gene ID" value="Caci_8530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8530"/>
    <dbReference type="eggNOG" id="ENOG5032WU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_488934_0_0_11"/>
    <dbReference type="OrthoDB" id="1452108at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="557" mass="59956" checksum="FC6DF0807B5CE500" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ92</accession>
    <name>C7PZ92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2632</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2632"/>
    <dbReference type="EnsemblBacteria" id="ACU71549">
        <property type="protein sequence ID" value="ACU71549"/>
        <property type="gene ID" value="Caci_2632"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2632"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_672301_0_0_11"/>
    <dbReference type="OMA" id="KPCERLG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="195"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="427" mass="44951" checksum="C8BC5D178D4CD5D2" modified="2009-10-13" version="1">MGSPGSPPPGPASGVGDGLGAPREDSAEDLYENAPCGYLSTAMDGTIVKINATLLGWLARDRDEVVGRRRFTDLLTVGGKLYHETHFAPLLQMQGEVGGVALELKTARGDRLPVLVTSKVKTGPDGEPLLIRTVVFDAHDRRSYETELLRARQEAEDAREAAEKATALVETERVRLQQLSTTLQTTLLPPDLPPVPGVEVAADYHVASVDEVGGDFYDLFRLSGDAWGFFLGDVCGKGVIAAATTSLIRYTLRATAPHVGSLPAILENLNNVLNQRYGSDLRYCTIVFGVLVPDTSGPGYSVTLASGGHPPALLLGADGKARYLPTPGGQFIGVLAQVDIATTTIRMGPGDTLLLYTDGLTEAHTIRPDRYGEEALLDFAAALAPTSAPVLVEAVSSLLDGFGDGVTDDAAILALSIPADGPKPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC7</accession>
    <name>C7PZC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786877.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2668"/>
    <dbReference type="EnsemblBacteria" id="ACU71584">
        <property type="protein sequence ID" value="ACU71584"/>
        <property type="gene ID" value="Caci_2668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2668"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_11"/>
    <dbReference type="OMA" id="WWFGFHA"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="29607" checksum="E5383030565775A6" modified="2009-10-13" version="1">MPAAVDLLRVPVNGIEVNVAVCGTGPEVLLLHGFPHTWQLWSSVMGPLSDQYRVIAPDLRGLGATTRAADGYDAENLAADAEGLLAALNVDSAAVVGIDAGTPPAFLLAMRRPDLVRRLVLMEAFLGRLPGAEDFLPAGPPWWFGFHAVPGLAEQVLAGHEPEYVDWFLTAGTQGRGIPAEVRDAFVAAYTGTESLRCAFEHYRAMPATARQIQAATLAGRLSVPTLAVGAHPVGPALYHQLRQVCDDVTRLDIAECGHIIPLDRPAALLTALTDFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE4</accession>
    <name>C7PZE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786894.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2686"/>
    <dbReference type="EnsemblBacteria" id="ACU71601">
        <property type="protein sequence ID" value="ACU71601"/>
        <property type="gene ID" value="Caci_2686"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2686"/>
    <dbReference type="eggNOG" id="COG3237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182085_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="9932" checksum="F4143604D7DA4C53" modified="2009-10-13" version="1">MSVGDKAKAAAKNVKGNVKEGVGRASGNERLTAEGKADKAAGTAQHKAAKAKESVKQTGKGATGKVKETTGKTVGNETLTLKGKAQQAAAKTKKKVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZG4</accession>
    <name>C7PZG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71621">
        <property type="protein sequence ID" value="ACU71621"/>
        <property type="gene ID" value="Caci_2706"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2706"/>
    <dbReference type="HOGENOM" id="CLU_2407868_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9482" checksum="C2B68D13FF2B77E4" modified="2009-10-13" version="1">MLDDVRDLLDRAGFRTRASGRGVTAEAVPEGVRVLWQPDLAQLGPIAGIKAAMYTAMGSILEGAGFQVRIGHTDLLVAAPAVASPPAAQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZQ1</accession>
    <name>C7PZQ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="6">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4705"/>
    <dbReference type="EnsemblBacteria" id="ACU73566">
        <property type="protein sequence ID" value="ACU73566"/>
        <property type="gene ID" value="Caci_4705"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4705"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="VSNDQMA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="38115" checksum="2CD5BC51DD5FE23A" modified="2009-10-13" version="1">MQNVVGDRAPVMADVARVAGVSQQTVSRVLNDRPNVRPATRDRVLGAIRELGYRPNAAARTLVTRRSNTLGVISFNTTLYGPASMLYGIEQAAKQHDYFVTVAALAAMDRRSVFEAVERLRDQAVEGIIVIAPQTTAVSALANMPSDVPLVAVGCGVHAALSAVAVDNEAGAERATSYLLDLGHRTVHHLAGPRTWLDAQEREAGWRRALTVRGAEVAEPFKGGDWSARTGYDLGRQIVRDPGVTSVFCANDHLALGLMRALQAAGRRVPEDVSVIGFDDIPDAEFFGPALTTVRQDFDELGRRALLALIRSIGRIGKVGSPSKLGKAANPGAGKRPGGPVAAIDPSLVVRASTARPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS3</accession>
    <name>C7PZS3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerate kinase</fullName>
            <ecNumber evidence="4">2.7.1.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.31" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793317.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4727"/>
    <dbReference type="EnsemblBacteria" id="ACU73588">
        <property type="protein sequence ID" value="ACU73588"/>
        <property type="gene ID" value="Caci_4727"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4727"/>
    <dbReference type="eggNOG" id="COG1929">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028255_0_0_11"/>
    <dbReference type="OMA" id="SIEMNEC"/>
    <dbReference type="OrthoDB" id="1292731at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="511" mass="49061" checksum="F79248FB1285315C" modified="2009-10-13" version="1">MPRSTAGHILLATDKFKGSLTAAQATTHLAAGLRRAAPALGIRTIPVADGGEGTVEAAVEAGFARVLTRATGPTGEPLEAAFAVRADTAVIEVAEASGLRRLPHGEPAPLSATSYGTGQLIRAALQAGCTRIILGLGGSACTDGGAGLAQALGARLLDAAGNELPPGGAALARLASIDLTNLAPINELIIASDVDNPLLGPSGAAAIYGPQKGATAEDVTLLNAALANWARVVQDAVAGRGYGSGPVPLPVPGAAVTGGSAARSASAELEVSVADRGFGAAARAEAGEAAGGAVPWSASAGPEVSAAGRGSGSVPVAEGAVSCSASAGLEVSAADRGFGSGTAGDLAGSVGEAIDLAPASAGDRVSGEGGAALGTDFAQTPGAGAAGGIGFGALALFGARLEPGIDIVLELADFAGKAAGARLVITGEGSLDPQSLRGKAPAGVARAAARVGVPVVAVAGVCSLTAAELAAAGIRAAYTLSGIEPELDRCVLNAGPLLERLAADVLAGVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ8</accession>
    <name>C7PZZ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795220.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6645"/>
    <dbReference type="EnsemblBacteria" id="ACU75491">
        <property type="protein sequence ID" value="ACU75491"/>
        <property type="gene ID" value="Caci_6645"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6645"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="YGQDDAH"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="23758" checksum="E4AC8114AB4CDC69" modified="2009-10-13" version="1">MRVLVVDDDEELAETLGVGLRRQSMAVDVAFDGLDGQEKALVNRYDVIVLDRDLPGRHGDEVCADLVAAGVEGRILMLTAASAIDDRVDGLALGADDYLPKPFAFAELVARIRALGRRAHPVVAPLLCRAGLELDAARHRATRDRRLLELGPKEFGVLELLLAADGRVVSTEELLERVWDDATDPVTTAVKVTMSRLRRKLGDPPVIETVARFGYRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0I8</accession>
    <name>C7Q0I8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent RecD-like DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recD2</name>
        <name evidence="4" type="ordered locus">Caci_8706</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecD family. RecD-like subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797245.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8706"/>
    <dbReference type="EnsemblBacteria" id="ACU77521">
        <property type="protein sequence ID" value="ACU77521"/>
        <property type="gene ID" value="Caci_8706"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8706"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007524_0_1_11"/>
    <dbReference type="OMA" id="HYIMHNT"/>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01488">
        <property type="entry name" value="RecD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006345">
        <property type="entry name" value="DNA_helicase_RecD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029493">
        <property type="entry name" value="RecD-like_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041451">
        <property type="entry name" value="RecD-like_SH13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14490">
        <property type="entry name" value="HHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18335">
        <property type="entry name" value="SH3_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01448">
        <property type="entry name" value="recD_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="348"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="359"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="740" mass="79440" checksum="62A0A0DE65DEC40F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q147</accession>
    <name>C7Q147_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787015.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2812"/>
    <dbReference type="EnsemblBacteria" id="ACU71722">
        <property type="protein sequence ID" value="ACU71722"/>
        <property type="gene ID" value="Caci_2812"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2812"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_5_0_11"/>
    <dbReference type="OMA" id="QWFACHG"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="17790" checksum="41D07CFDB483CAA5" modified="2009-10-13" version="1">MTERFITHSTFVLERVYDAPVERVFAAWGDQEVKRRWFSPTMEVDFRVGGTERSTFRNQPDGPLFTYEAVFRDIVPNERIVLTNHMHSDQDRIAVNLVSIEFAPENDGTRVTITDHGTYLDGRDRGDWREEGVGQELDRLAIELRPTALTSTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q166</accession>
    <name>C7Q166_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2832"/>
    <dbReference type="EnsemblBacteria" id="ACU71741">
        <property type="protein sequence ID" value="ACU71741"/>
        <property type="gene ID" value="Caci_2832"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2832"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029872_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982777" evidence="1">
        <location>
            <begin position="25"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="207"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="40412" checksum="BBA3DCB2A7BCDF61" modified="2009-10-13" version="1" precursor="true">MIRLRTALAATAAAVLLVLPVSSAAGPATATATTGTGWTASWGSAPAYAPVSGPWDNETLRMVVRTSGGGTSLRIRLSDAFSPQAAQIGHVTVGTQLNGGTTLEPVPTTVTFGGAQAVTIPAGGQVASDPVTFTVAPNTRLLVSIYVASGAALAQTSRHDVATETEYNHNGGDVSTAEYYPTSNTFGFVTMLDGVDVSSTTPSTVVAVGDSITDGTGTGIDTDTRWPNYLADRVSAAGLSVIDEGIAGNWVTQDKGSLGPSLQHRWQQDVLDQPGVRSVIDADGINDLRGGVTAQVLEQAQASLVASAHAAGLRILLSTITPCEGDSLCTSAVETQRLAYNAWVISGVSGADGVADFNSATAVNENLKTAYDSGDHLHPNSAGAAVMANSLDVTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q181</accession>
    <name>C7Q181_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2847"/>
    <dbReference type="EnsemblBacteria" id="ACU71756">
        <property type="protein sequence ID" value="ACU71756"/>
        <property type="gene ID" value="Caci_2847"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2847"/>
    <dbReference type="eggNOG" id="ENOG5033S8G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_445988_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="612" mass="61780" checksum="3654AEF0A15DF684" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K8</accession>
    <name>C7Q1K8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793466.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4877"/>
    <dbReference type="EnsemblBacteria" id="ACU73737">
        <property type="protein sequence ID" value="ACU73737"/>
        <property type="gene ID" value="Caci_4877"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4877"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="VGATNWR"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="37030" checksum="84CBA55B447CFE6C" modified="2009-10-13" version="1">MTDDRSARPAGVAKRRDGPVTIAYIAESAGVSVPTVSKVLNGRPGVSDDTRARIEDLIIQHGYRKPPFRSNTLELVFRELESLWAVEIIRGVEQVARKHRIGVTVSEFGLHDSLPEPMDDMVFRRPKAVLSVAQLSDAEREQLAANGIPFVVFDPISELPEDVPFVGATNWRGGQTATRHLIGLGHRRIAMVRGPAGLMCFDARTAAYAFTMAAAGLPVDPELTVEAEPSKEAGYAAACGLFALADRPTAVFASNDLQAIGVYQAAREAGLRIPDDVSVVGFDDLPVAAWLDPQLTTVHQPLSQMAAAATELALALGRGEETPQLGVELATTLTVRRSTAPPKPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1U0</accession>
    <name>C7Q1U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795369.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6800"/>
    <dbReference type="EnsemblBacteria" id="ACU75641">
        <property type="protein sequence ID" value="ACU75641"/>
        <property type="gene ID" value="Caci_6800"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6800"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="GWLWAAY"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="45331" checksum="A6245DAC759F9F7D" modified="2009-10-13" version="1">MADGPNATGRRKLGRPFTRLWSAYAISTLGTYFAFNAFSLILIRILHAGAAQVAALSASGAAVGALIALPLGPWVEHRRKRPVMMAMDLMRFAAMLTIPITYGFGALTFAQLLAVAIVVGAADITFTAASGAYLKALLPREDLLTANGRFESTQWSAIVLGPPLGGAAFALLGPVATVIADAVSYLLSALGIRAIGAGHEADAGDRATTVPEAGDRIRDRSTGLRAADLVAGWRHILGNPALRPLLLNNAMVSGLIMAGEPLLSVLMLGPLGLAPWEYGLAFAIPCLGGLVGSRLAPRLVARFGRATILRVAGTLRAVWPVGLAFLQPGLPGLVLVVVLEMGLITTISVYNPVLATHRLEQVGPGNVTRVLSAWSITTKTTIAAATALWGVIATVTSPRFGLGLAGALLLASPLLLPRGERVGLLAEHAPDPVSSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2C1</accession>
    <name>C7Q2C1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fdhD</name>
        <name evidence="4" type="ordered locus">Caci_0829</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785058.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0829"/>
    <dbReference type="EnsemblBacteria" id="ACU69763">
        <property type="protein sequence ID" value="ACU69763"/>
        <property type="gene ID" value="Caci_0829"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0829"/>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056887_3_0_11"/>
    <dbReference type="OMA" id="RYCAGAT"/>
    <dbReference type="OrthoDB" id="948173at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30592">
        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00129">
        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="31276" checksum="01CF64438853202B" modified="2009-10-13" version="1">MSRVTARRRIVRLDGSAGPAEAVLRRGGEEHMAAEEPLEMRIGGHPFTVTMRTPGDDFDLVAGHLTAEGVLSGPDDLLRMKFCSADNGCSSTAYTDGEASLAFADGDPLNIVDVTLAPGVELPEERLRRSSYVTSACGVCGKTSIDAVHAAVRWPVAEDDVKLSAEVLFTLPDRMREAQKIFAKTGGLHAAALFTATGDLLCLREDVGRHNAVDKVLGWALRAGRLPLREHVLAVSGRASFELVQKAVAGGIPVLTAVSAPSSLAVSLAAESGLTLVGFLRGRTANVYCGSERVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2N4</accession>
    <name>C7Q2N4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsZ</name>
        <name evidence="5" type="synonym">rpsN</name>
        <name evidence="6" type="ordered locus">Caci_0944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785171.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0944"/>
    <dbReference type="EnsemblBacteria" id="ACU69876">
        <property type="protein sequence ID" value="ACU69876"/>
        <property type="gene ID" value="Caci_0944"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0944"/>
    <dbReference type="eggNOG" id="COG0199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_3_0_11"/>
    <dbReference type="OMA" id="RAYTRCN"/>
    <dbReference type="OrthoDB" id="2032609at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_B">
        <property type="entry name" value="Ribosomal_S14_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023053">
        <property type="entry name" value="Ribosomal_S14_Z"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="6866" checksum="E3BC27064D15DB03" modified="2009-10-13" version="1">MAKKALINKALAKPKFKVRGYTRCSKCGRPHSVYRKFGLCRVCLREMAHAGELPGVTKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q308</accession>
    <name>C7Q308_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787193.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2991"/>
    <dbReference type="EnsemblBacteria" id="ACU71900">
        <property type="protein sequence ID" value="ACU71900"/>
        <property type="gene ID" value="Caci_2991"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2991"/>
    <dbReference type="HOGENOM" id="CLU_2166444_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="110" mass="11726" checksum="BEF9F4615193CFCA" modified="2009-10-13" version="1">MKSNTKHVAADAAGDEKLAEIRTLLNLPYPEIAAKSSALSLMIAVSRELLARLDDQAVPEFPGRPGSRWRDADGDAWMLGDDGVMRMTNTPSDPNDVAVAYGPMTRAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q327</accession>
    <name>C7Q327_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793492.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4903"/>
    <dbReference type="EnsemblBacteria" id="ACU73763">
        <property type="protein sequence ID" value="ACU73763"/>
        <property type="gene ID" value="Caci_4903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4903"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108911_0_0_11"/>
    <dbReference type="OMA" id="VSGDHQW"/>
    <dbReference type="OrthoDB" id="1380653at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03450">
        <property type="entry name" value="NodN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039375">
        <property type="entry name" value="NodN-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="15940" checksum="B99C6C8997DFD974" modified="2009-10-13" version="1">MPRTVTGVAGLLDLGAADLGHSSWLDIGQERVNTFADATGDHQWIHVDPERAATGPFGGAIAHGYLTLSLLIPLWSELLTVADIGMAVNYGLNKVRFPAPVRVGSRIRAHGAIASVTEVKGGAEVVVDLSVEIEGQHKPACAAQAVYRFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q356</accession>
    <name>C7Q356_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-L-fucosidase</fullName>
            <ecNumber evidence="7">3.2.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4932</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793521.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4932"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH29">
        <property type="family name" value="Glycoside Hydrolase Family 29"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73792">
        <property type="protein sequence ID" value="ACU73792"/>
        <property type="gene ID" value="Caci_4932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4932"/>
    <dbReference type="eggNOG" id="COG3669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_6_0_11"/>
    <dbReference type="OMA" id="HHIATYG"/>
    <dbReference type="OrthoDB" id="439010at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="PTHR10030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982847" evidence="5">
        <location>
            <begin position="37"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="6">
        <location>
            <begin position="526"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="663" mass="71106" checksum="0CB4EA7003B54C19" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q378</accession>
    <name>C7Q378_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4954</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4954"/>
    <dbReference type="EnsemblBacteria" id="ACU73814">
        <property type="protein sequence ID" value="ACU73814"/>
        <property type="gene ID" value="Caci_4954"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4954"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="MYGALNN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="32888" checksum="EF2D4A5FDD6852DD" modified="2009-10-13" version="1">MSSPTATTGRTTARRGALRALWPGRAGHGFVAAYVVLLIAFGIVPTCYAVYFAFTDGNARFSGLSNFSRAAADFRFVPAVEHVALYLVFWLVALVVLVVGLSLLLYELSARGVSKALRFLYYIPGALAGAAGVMVWLFVLDPSVSPVAFLLRAMGFATFGQVVAPGHLPVLFTLIAFWTGAGGWIVVMHGALNNIPREVIEAARIDGASAWQTARRIQIPMLRKWIVYMVILTFAGGTQLFVEPQLLAQASVGVAGRDYSLNQLSYDFAFQNNDVNTAAAISVELLLVGLVVAALFVARSGFFDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U1</accession>
    <name>C7Q3U1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8886</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797423.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8886"/>
    <dbReference type="EnsemblBacteria" id="ACU77699">
        <property type="protein sequence ID" value="ACU77699"/>
        <property type="gene ID" value="Caci_8886"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8886"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066229_0_0_11"/>
    <dbReference type="OMA" id="FTWWWSP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34607" checksum="2CF751A525C6450C" modified="2009-10-13" version="1" precursor="true">MKGLIWLTWRQHRWPIAVSAALTVILVVLMALTASDLGSLAAKCADHAARCQVAKTQSVPSHASYLMNTVVFLPVLVAVFWGVPLLAREFEQRTLPLAWSQDVSRDKWLAGKSTVMVVLVAAMGTALAAESEHLAHQFHAYTGESLFEGTQFQAGGWLPLTLGLAWLAVGIAAGAATRRVLVAIAVVGGLWIVRMVGMVQLRPHFATPVTMIKQFDLGRVGAGPAAPTASNDMSLSNGNVPFLDAHGGTHSPQQVMDGWCGSADDMNACLHQHGIIGTLDKFQPASRMGTFHLIENGMNLGLFVIALAVAWWCVRRTRTTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3X0</accession>
    <name>C7Q3X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77728">
        <property type="protein sequence ID" value="ACU77728"/>
        <property type="gene ID" value="Caci_8915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8915"/>
    <dbReference type="eggNOG" id="ENOG5033JRJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_618080_0_0_11"/>
    <dbReference type="OMA" id="IVNSMIN"/>
    <dbReference type="OrthoDB" id="1046714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="474" mass="51055" checksum="2FF9111F4F1ADBF1" modified="2009-10-13" version="1">MLDLWHGTHGADRFDLTALPWWRVCRVDAVAPGQGPVPSFLDDLGKAFADQGHEVGRPVSVAGVGSRVELDVLLVHIPVPAGPGTLLDRVAEQYPPLMVTLRRTGDVRGGVRNLVGVFEVDEPLAGAKHLEVVQLARVLMARVGAPKTLFVYPDPETGEILEATLCTMEGGHPSITTDIVRDIRDRLVAVACATEVNDRLDRVPDSVPTSAFDAAGSPRVLVSAGRRMGNLGLLPPPHRVSDYVSVTMASAYQRYLGIKGFSEGMMFVFDPDLQALVVTASGSFEVDKRDLRPEDVVVVDHRLDGGRLRLLEVGGAGQKGPSVEAWEVCALMAAAPKIRVSKDASGIWRPDPEGTVEVPSVRGGLHAHVGVDEADETLIESIPPDRTAYPYGFGCGTDLMVDVAAATVRRSQAINDAGDSRSYVRWPMLYHGEMALELWTPDVPDEPLTGLLDLFDPAGRAAIAFRTDHVDQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4D1</accession>
    <name>C7Q4D1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TAP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1065"/>
    <dbReference type="MEROPS" id="S33.006"/>
    <dbReference type="EnsemblBacteria" id="ACU69991">
        <property type="protein sequence ID" value="ACU69991"/>
        <property type="gene ID" value="Caci_1065"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1065"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_1_11"/>
    <dbReference type="OMA" id="RSACATD"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982516" evidence="2">
        <location>
            <begin position="38"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="101"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="4">
        <location>
            <begin position="417"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="57624" checksum="5AC09D48E386D7A9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M2</accession>
    <name>C7Q4M2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787284.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3082"/>
    <dbReference type="EnsemblBacteria" id="ACU71991">
        <property type="protein sequence ID" value="ACU71991"/>
        <property type="gene ID" value="Caci_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3082"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_6_0_11"/>
    <dbReference type="OMA" id="MLEFWVD"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="14272" checksum="4200440444B9F9B5" modified="2009-10-13" version="1">MSAVDTFLEEARSGLRRVSPQEADRLRREGALLIDIRPHANREAEGEIPGALPVERIHLEWRLAPDNEWRLPGVTADSQVIVFCNEGYASSLAARDLQLLGLVHATDLVGGFRAWAEAGLPTEAGGRPALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4U1</accession>
    <name>C7Q4U1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793618.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5029"/>
    <dbReference type="CAZy" id="GH95">
        <property type="family name" value="Glycoside Hydrolase Family 95"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73889">
        <property type="protein sequence ID" value="ACU73889"/>
        <property type="gene ID" value="Caci_5029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5029"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013559_0_0_11"/>
    <dbReference type="OMA" id="ADWPANT"/>
    <dbReference type="OrthoDB" id="49249at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980592" evidence="2">
        <location>
            <begin position="35"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="948" mass="99270" checksum="C7F2FB6E40D6ECC2" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4V1</accession>
    <name>C7Q4V1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5039"/>
    <dbReference type="EnsemblBacteria" id="ACU73899">
        <property type="protein sequence ID" value="ACU73899"/>
        <property type="gene ID" value="Caci_5039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5039"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="SCATERY"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="993" mass="107209" checksum="30CCBA780AB08C72" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q560</accession>
    <name>C7Q560_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6999</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795557.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6999"/>
    <dbReference type="EnsemblBacteria" id="ACU75829">
        <property type="protein sequence ID" value="ACU75829"/>
        <property type="gene ID" value="Caci_6999"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6999"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_3_2_11"/>
    <dbReference type="OMA" id="DIHTWMR"/>
    <dbReference type="OrthoDB" id="610569at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="376"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="609" mass="67298" checksum="3DC2981C90929E30" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q593</accession>
    <name>C7Q593_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycyl-tRNA synthetase</fullName>
            <shortName evidence="7">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyQS</name>
        <name evidence="9" type="ordered locus">Caci_7032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glycine to tRNA(Gly).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795590.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7032"/>
    <dbReference type="EnsemblBacteria" id="ACU75862">
        <property type="protein sequence ID" value="ACU75862"/>
        <property type="gene ID" value="Caci_7032"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7032"/>
    <dbReference type="eggNOG" id="COG0423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_2_1_11"/>
    <dbReference type="OMA" id="EPSYGID"/>
    <dbReference type="OrthoDB" id="626850at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00253_B">
        <property type="entry name" value="Gly_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022961">
        <property type="entry name" value="Gly_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="116"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="209"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="321"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="194"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="204"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="281"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="325"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="460" mass="52701" checksum="B80DF614436FA920" modified="2009-10-13" version="1">MAADKIETIVRLAKSRGFVFPSSEIYGGTRAAYDYGPLGVELKENIKRQWWKAMVTGREDVVGLDSSVILAREVWEASGHVKEFTDPLTECQSCHKRFREDHLIEAYEAKHNRVPERGLADINCPNCGNKGTFTEPKVFNLMLQTHLGVTMDDAGLAYLRPETAQGIFVSYKTVRDASRKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDEQWFEYWLNERYNWWTDLGLKPENLRFFEHPAEKLSHYSKRTVDIEYRFNFGGQEFSELEGVANRTDFDLSTHAKHSGEDFTQLEQETGERWTPFVVEPAAGVNRGMLAFLLDAYAEDEAPNAKGQMEVRKVLRLDKRLAPVKAAVLPLSRNVDLSPKARDLAQLLRKNWNVEFDDAGAIGRRYRRQDEIGTPFCITVDFDTLDDQAVTVRERDSMEQQRVALDQVEGYLAARLIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5C3</accession>
    <name>C7Q5C3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795620.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7062"/>
    <dbReference type="EnsemblBacteria" id="ACU75892">
        <property type="protein sequence ID" value="ACU75892"/>
        <property type="gene ID" value="Caci_7062"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7062"/>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082566_0_1_11"/>
    <dbReference type="OMA" id="PRQPCVK"/>
    <dbReference type="OrthoDB" id="1643056at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="38"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="24991" checksum="B3B0F874BBA63572" modified="2009-10-13" version="1">MSIARPEAGSGLLISVNVGMPRDVELNGEVQQTAIFKRPVPGRVKVADHHMDGDRQADQVNHAGVHKAVYAYSREDLDFWAVELGREIEDGFVGENLTISGYDVSHAVVGERWRVGGAEFEVAQPRIPCWKLGVRAADQSMPRRFERALRPGAYLRVLTEGDVGAGDQVAVASRPAHGFTVADASRIFHRDRAEAPRLLEVAELAPPLKKWARKRLGLPLDDAGESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5L0</accession>
    <name>C7Q5L0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_9008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797545.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9008"/>
    <dbReference type="EnsemblBacteria" id="ACU77821">
        <property type="protein sequence ID" value="ACU77821"/>
        <property type="gene ID" value="Caci_9008"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9008"/>
    <dbReference type="HOGENOM" id="CLU_1412919_0_0_11"/>
    <dbReference type="OMA" id="TEFWNGS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20267" checksum="7681186E9B00D174" modified="2009-10-13" version="1">MTTRPETVTLMHTGLLVPADHPQVVSMSSLPTPSGATLVALVRFGGHDIGTIEGTDEGGDLTFRPTGSFSPAKVNEFAAQCRHHGRPVTGSQLMALLVEEWQISERLLQAVAEGQTVARFLRDGGTLLTLAIRVFIPPQETGLSVAAVVPAAVAAALAEVADDPGGHWQVWTGTIWQQLPGSEAVEQDGDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D2</accession>
    <name>C7Q6D2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amylo-alpha-16-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3231"/>
    <dbReference type="EnsemblBacteria" id="ACU72138">
        <property type="protein sequence ID" value="ACU72138"/>
        <property type="gene ID" value="Caci_3231"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3231"/>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026835_0_0_11"/>
    <dbReference type="OMA" id="QGTVWPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024742">
        <property type="entry name" value="Glycogen_debranch_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="PTHR10569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12439">
        <property type="entry name" value="GDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDE_N" evidence="2">
        <location>
            <begin position="35"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="GDE_C" evidence="1">
        <location>
            <begin position="294"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="659" mass="69460" checksum="6AD1335513456894" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6G3</accession>
    <name>C7Q6G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5139</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5139"/>
    <dbReference type="EnsemblBacteria" id="ACU73998">
        <property type="protein sequence ID" value="ACU73998"/>
        <property type="gene ID" value="Caci_5139"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5139"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_11"/>
    <dbReference type="OMA" id="LVIYYLP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="24"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="519" mass="53081" checksum="B392A784A184091B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6H8</accession>
    <name>C7Q6H8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793742.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5154"/>
    <dbReference type="EnsemblBacteria" id="ACU74013">
        <property type="protein sequence ID" value="ACU74013"/>
        <property type="gene ID" value="Caci_5154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5154"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079334_0_0_11"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="29600" checksum="FE1CE51D916070A9" modified="2009-10-13" version="1">MPEDVSESAGRRMLITGAAGGVGTFLRTGLAALGWQLRCLDLRMPDDPGGAEWIVGDISDAATLDAAMAGIDVVIHLAAIPIEDHFDAILHANIDGTYRVFDAAARAGVPRFLFASSNHAVGYYERSSLGNGRIPADARTRPDTFYGVSKVFGEAIGSFYHDRHGLQVACVRIGACYAEPKTRRMLDTWFSPGDAVRLFHTLATTPDLGYEIVYGVSANRTAWGNLDSARRLGYEPQDDSSAFADRFANQPIDPDDPEVRYLGGDFTTATPGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6M1</accession>
    <name>C7Q6M1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5197</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793785.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5197"/>
    <dbReference type="EnsemblBacteria" id="ACU74056">
        <property type="protein sequence ID" value="ACU74056"/>
        <property type="gene ID" value="Caci_5197"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5197"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_13_1_11"/>
    <dbReference type="OMA" id="SKQDCFM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22755" checksum="B8DD328835887F6D" modified="2009-10-13" version="1">MDPDTLPAPLPRGNHGLSREEVSAAQRTRLLNGMLEVVAERGYAAATVGAVLSRARISRQTFYEHFTDKQDCFLAAFDRSADRFALLIEHSLGSPKDPALQRLDRIIEAYLGALAANPTLARIFMIEIYAAGYPAVSRRLARAEAFAAILAEAVTIGRPWRGGLDPLFVARAVTGAVSGLVTEQINAGEIKSLPELRPQIVAFVAGLSAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V8</accession>
    <name>C7Q6V8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-amino-acid oxidase</fullName>
            <ecNumber evidence="3">1.4.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.4.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7142"/>
    <dbReference type="EnsemblBacteria" id="ACU75971">
        <property type="protein sequence ID" value="ACU75971"/>
        <property type="gene ID" value="Caci_7142"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7142"/>
    <dbReference type="eggNOG" id="COG1231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004498_8_2_11"/>
    <dbReference type="OMA" id="YTHAWIA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001716">
        <property type="term" value="F:L-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="2">
        <location>
            <begin position="125"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="624" mass="66965" checksum="23A6BC2D2EF9A0F0" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X0</accession>
    <name>C7Q6X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795711.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7154"/>
    <dbReference type="EnsemblBacteria" id="ACU75983">
        <property type="protein sequence ID" value="ACU75983"/>
        <property type="gene ID" value="Caci_7154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7154"/>
    <dbReference type="HOGENOM" id="CLU_148727_5_2_11"/>
    <dbReference type="OMA" id="FTGHEQQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028037">
        <property type="entry name" value="Antitoxin_Rv0909/MT0933"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14013">
        <property type="entry name" value="MT0933_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6694" checksum="284C139269FF3DD8" modified="2009-10-13" version="1">MNVLDKLKQMFTGHEQQVDKGSDKAADLAKKKAGGKYDQQIDTGRDKLKDQFGTQDRPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q729</accession>
    <name>C7Q729_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7213"/>
    <dbReference type="EnsemblBacteria" id="ACU76042">
        <property type="protein sequence ID" value="ACU76042"/>
        <property type="gene ID" value="Caci_7213"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7213"/>
    <dbReference type="eggNOG" id="ENOG50347KT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116294_1_0_11"/>
    <dbReference type="OMA" id="AMATDTW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980656" evidence="1">
        <location>
            <begin position="18"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15795" checksum="42F32E6B649BB39A" modified="2009-10-13" version="1" precursor="true">MATLAAAAAATLVTAMATDTWSGVRTTVAKLFRRRRRGKAAQRIETELDADSAAVERAAEPDAARRALVGRWTLEFSALLDEDPECVVPLAELVQAYASDLAENRRIFITRQTAVAHDYGSVFAVQNGDMHLHTHSRSTTDRTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q737</accession>
    <name>C7Q737_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7221"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH30">
        <property type="family name" value="Glycoside Hydrolase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76050">
        <property type="protein sequence ID" value="ACU76050"/>
        <property type="gene ID" value="Caci_7221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7221"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014379_3_0_11"/>
    <dbReference type="OMA" id="FGGIAWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0430">Lectin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982861" evidence="5">
        <location>
            <begin position="41"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="6">
        <location>
            <begin position="506"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="634" mass="67376" checksum="8A8DCF8EE0F7AF05" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7R9</accession>
    <name>C7Q7R9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3355"/>
    <dbReference type="EnsemblBacteria" id="ACU72262">
        <property type="protein sequence ID" value="ACU72262"/>
        <property type="gene ID" value="Caci_3355"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3355"/>
    <dbReference type="eggNOG" id="COG2807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038046_1_0_11"/>
    <dbReference type="OMA" id="VTWLPTI"/>
    <dbReference type="OrthoDB" id="806182at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="423" mass="42686" checksum="30F9B3BBE4348A38" modified="2009-10-13" version="1">MISGMSVDEDAAHDTAAPNPAALTTSLLIAIILVAANLRAGLTGVGPLLPSIENSTGLSDAWGGLLLTLPLLTFAATSPLAGRAARRHGARRVLALSLPVLAAGLVVRSLPGTVFLFGGTVVIAAAIAVGNVLLPPVVRGSVPEHRIGQVTGVYVTAMGLVAAISSGVSVPLADVLPGGWRSALGCWAVLAVLAFPAWIPHLRRSAQPKAETAAKESKAAAPPPAKTPSLWRSALAWQVSLFMGLQSLGFYATIAWLPSIVHDHGTPAATAGWELFLYQAVGLLASITLPLLTRRRLDQRLLAATASALGAAGFALLAIAPSLAVLTCVLNGFGSGATLVLALTFQGQRAAKGPQTAALAAMAQTVGYTVAAIGPLLLGALHGATSGWALPLTLLAGLACVQAVIGFGAGRDLTVGPATPPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R2</accession>
    <name>C7Q8R2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785621.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1404"/>
    <dbReference type="EnsemblBacteria" id="ACU70327">
        <property type="protein sequence ID" value="ACU70327"/>
        <property type="gene ID" value="Caci_1404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1404"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_385752_0_0_11"/>
    <dbReference type="OMA" id="MRPIRER"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="9"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="400"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="716" mass="73770" checksum="EED879DDD09B7A99" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8V2</accession>
    <name>C7Q8V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785661.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1444"/>
    <dbReference type="EnsemblBacteria" id="ACU70367">
        <property type="protein sequence ID" value="ACU70367"/>
        <property type="gene ID" value="Caci_1444"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1444"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056341_0_0_11"/>
    <dbReference type="OMA" id="QGGTYRV"/>
    <dbReference type="OrthoDB" id="250058at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045641">
        <property type="entry name" value="MmpI-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19307">
        <property type="entry name" value="PCLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="103"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="475" mass="51662" checksum="2696E815EB1710C4" modified="2009-10-13" version="1">MPTDPMPQDLVQDSPDSQLSLSTAAARNLATTTKTVPQMQGITSRWLLRKLPFVQVSGGTYRVNRRLTHAVGRGRIAFDQSGEDIRVLAPTLTELPILRGLDDEALLTELAGRFTPRRFAAGEQLAEAGQPVTEILVVGHGKVAKVGTSKYGETTIVGSLAGGDHLGDEAVAGGVVDSVPWGYGARATTSGVLLALPLSAFQELLDRSETLRTQVASHAAQRDKPTNKKGEAEISLAAGHEGEADLPGTFVDYELSPREYQLSVAQTVLRVHSRVADLYNDPMNQTEQQLRLTVEALKERQEYELVNNGQFGLLANAANEQRIHTHSGPPTPDDMDELLSMRRSTKFFLAHPKAIAAFGRECTKRGVYPTSGTVDGNRVFAWRDVPIYPCSKIPITDGHTTSILAMRTGEDEQGVVGLHQTGLPDEYEPSLNVRFMNIDDKAIISYLVSAYYSAAILVPDALGVLENVELDRPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9K6</accession>
    <name>C7Q9K6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74352">
        <property type="protein sequence ID" value="ACU74352"/>
        <property type="gene ID" value="Caci_5493"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5493"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1632372_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="17584" checksum="7821B066CA6E106D" modified="2009-10-13" version="1">MIVIMAIKNPLMGAAEIGKLFDVSRQRVQQLIAKADFPVPEADLAMGKVWSTRNVKDWGLQAGRPFLVAYAFRDRDGQWHGPEHRLETGYVEGVLAISDDANAKAFAGQTITLRCGFLAGQPNPVAGDISANFAIVTGPNDQRYGVLLTHEVADLLAGTYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA11</accession>
    <name>C7QA11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1486</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785703.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1486"/>
    <dbReference type="EnsemblBacteria" id="ACU70409">
        <property type="protein sequence ID" value="ACU70409"/>
        <property type="gene ID" value="Caci_1486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1486"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034004_1_1_11"/>
    <dbReference type="OMA" id="DPFPVKG"/>
    <dbReference type="OrthoDB" id="402639at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="180"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="41620" checksum="F05CB5913C984383" modified="2009-10-13" version="1">MTETATASAASATATKDPFPVKGMDAVVFAVGNAKQAAHYYSTAFGMRVVAYSGPETGRADRVAYVLESGSARFVFKGSVRPGTEIALHVAEHGDGVTDLAIAVPDVYAAYEYAVGHGATGLEKPHEVEDENGVLVRAAIATYGDTRHSLVDRSRYTGAYAPGYVERAPLVEPNARIFQAIDHCVGNVELGKMDEWVDFYRHVMGFTNMAEFIGDDIATDYSALMSKVVADGTRKVKFPLNEPAIAKKKSQIDEYLEFYGGPGVQHIALNTGDILATVDAMRAAGVEFLETPDSYYEDEELRARIGTVRVPVEELQKRKILVDRDEEGYLLQIFTKPVQDRPTVFFELIERHGSQGFGKGNFKALFEAIEREQERRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA37</accession>
    <name>C7QA37_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="5" type="ordered locus">Caci_1514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1514"/>
    <dbReference type="EnsemblBacteria" id="ACU70435">
        <property type="protein sequence ID" value="ACU70435"/>
        <property type="gene ID" value="Caci_1514"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1514"/>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_0_0_11"/>
    <dbReference type="OMA" id="DEFYHAD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="18"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="108"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20366" checksum="64557CF9444B7898" modified="2009-10-13" version="1">MSPDVENPSGRPEALRLVVGRIGRAHGIRGQATVEVRTDDPELRFAPGSRLLTEPAERGPLVVTDMRFHSGILLLAFEGVADRNAVEALRNTILVVEADPDETPEDPEEFYDHQLVGLPVELADGTVLGEIADLLHLPGQDVLAVKRPDRPEVLIPFIKQFVPVVDVANKRIVVDPPAGLLDLDSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA93</accession>
    <name>C7QA93_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785785.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1570"/>
    <dbReference type="EnsemblBacteria" id="ACU70491">
        <property type="protein sequence ID" value="ACU70491"/>
        <property type="gene ID" value="Caci_1570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1570"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_13_1_11"/>
    <dbReference type="OMA" id="VCGFEHG"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="21631" checksum="A011CA954AC00431" modified="2009-10-13" version="1">MSELILLRHGETEWSRSGRHTGLTDLPLTTVGEDQARAAAKLLAGRSFGAVYTSPLTRAVRTAELAGLTDATPDPDLLEWDYGGYEGVTTEEIHEKHPGWYLWDDGIVPGDHEHPGETIEQVGARVDRVLTRVRPLLADGEGEDVCLVAHGHVLRVLCARWLGLPPTGGRFFRLDTAAVSRLGFEHARPVVDGLNQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC3</accession>
    <name>C7QAC3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792151.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3516"/>
    <dbReference type="EnsemblBacteria" id="ACU72422">
        <property type="protein sequence ID" value="ACU72422"/>
        <property type="gene ID" value="Caci_3516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3516"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024866_0_0_11"/>
    <dbReference type="OMA" id="KGSGWDM"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="664" mass="70749" checksum="AEF6B08AC34A76E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC9</accession>
    <name>C7QAC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792157.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72428">
        <property type="protein sequence ID" value="ACU72428"/>
        <property type="gene ID" value="Caci_3522"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3522"/>
    <dbReference type="HOGENOM" id="CLU_378423_0_0_11"/>
    <dbReference type="OrthoDB" id="286403at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="732" mass="77137" checksum="B766FF91A176B2FC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAF3</accession>
    <name>C7QAF3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792181.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3547"/>
    <dbReference type="EnsemblBacteria" id="ACU72452">
        <property type="protein sequence ID" value="ACU72452"/>
        <property type="gene ID" value="Caci_3547"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3547"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_11"/>
    <dbReference type="OMA" id="TDHMTRL"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="42021" checksum="7BFBFCBA76313DA2" modified="2009-10-13" version="1">MTAVVTGLGVAAPNGLGTEDYWKNTLAGVSGIGPVKRFDAAGYPVRLAGEVPGFQAADHLPNRLLPQTDHMTRLALVAADWALADADVDPAAWPEYDMGVVTASSSGGFEFGQGELQNLWSRGGQYVSAYQSFAWFYAVNTGQISIRNGMRGPAGVLVSDQAGGLDAVAQARRQVRKGGRLVLSGGVDGSVCPWGWVAQIAARRMSECDDPARAYRPFAADATGHVTGEGGALLVVEDAASARARGVRVYGEIAGYCATFDPKPDTGRGPALERAIRTAIQDAHLTPDRIGVVFADAAGVPELDRIEARALVSVFGADGVPVTAPKTMTGRMLSGAASLDLAAALLALRDGVIPPTVNVLPDPAYQLDLVVDAPRESRFDAALVLARGYGGFNSAMVLTRGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAM4</accession>
    <name>C7QAM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792252.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3620"/>
    <dbReference type="EnsemblBacteria" id="ACU72523">
        <property type="protein sequence ID" value="ACU72523"/>
        <property type="gene ID" value="Caci_3620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3620"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_6_2_11"/>
    <dbReference type="OMA" id="IPHTWIQ"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="17175" checksum="2B7A67C72C02E35E" modified="2009-10-13" version="1">MIQQFPDDTFPDGKAEAFWFLGGQSRILVPGSETGGALSVMEFLDTAGHAPPRHIHEDEDEVWIVLDGEVSFFVADKRLDLHTGQIAHGPRGVPHSYLVRSPTARLAVAFAPSRIEGWFSANGTPATPLDEEPAAFDIGSILASADDFRLRVAGPPPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAY0</accession>
    <name>C7QAY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794182.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5594"/>
    <dbReference type="EnsemblBacteria" id="ACU74453">
        <property type="protein sequence ID" value="ACU74453"/>
        <property type="gene ID" value="Caci_5594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5594"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069129_7_4_11"/>
    <dbReference type="OMA" id="HLVFETR"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="42"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="27177" checksum="2C6A716C3A4D7470" modified="2009-10-13" version="1">MPDAIFAHPRLAEIYDTFDGDRADLDAYVAITAEFAGGRASVVDVGCGTGNLAVRLAALGHAVAGVDPAAASLAVARAKPHADAVTWIEGDATALPSLHADIALMTGNVAQVFLTDEDWTGTLRAIAAALRPGGHFVFETRRPERRAWEEWTVDSAPVVREVPGVGIVEERREELRVDLPYVYFRGAYRFPDGSVLRSESTLRFRDREEVEASLAACGFEIVDVREAPDRMGKEYVFITRTQAGHRPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH2</accession>
    <name>C7QBH2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1628</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1628"/>
    <dbReference type="EnsemblBacteria" id="ACU70549">
        <property type="protein sequence ID" value="ACU70549"/>
        <property type="gene ID" value="Caci_1628"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1628"/>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="HPHFEFK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="137"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="201"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="46315" checksum="222FAFC585D35D68" modified="2009-10-13" version="1">MQEVHGIQGVMAGNSGAVDSTYGGEVGPAAVPQGVRRRGLTIRLRMTITYGASVFVTGAVLIYTAYTLFKWRLGHPVADVSEPADCQRPKASMTLAETKNCKAIADQQILRQIDKPLIFVLLISAVVALVIGYFLAGRFLHPINRITRMARRVASRPDRSMHARIDMDGPQDELVELAQTFDGMLDRLDQAFEGQRRFVGNASHELRTPLAINRTLLEVTLMDPEASEQTRQLCRTLLATNERSERMIEGLLLLARADNEPAHREDVDLAEVAFRSVTQCELEAAERQVAIRTSLQQVSVSGDGILIERIAMNLIQNALRHNIGAGGWVDVLSYDRSTDLPGHGLLVVANTGPEVPAYAVETLFEPFKRGTQPSGASPARDPKDKGVGLGLSIVRSVVRAHGGRVAAEPRPGGGLIVRVWLPVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBM7</accession>
    <name>C7QBM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1683"/>
    <dbReference type="EnsemblBacteria" id="ACU70604">
        <property type="protein sequence ID" value="ACU70604"/>
        <property type="gene ID" value="Caci_1683"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1683"/>
    <dbReference type="HOGENOM" id="CLU_815574_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="33291" checksum="60CBFAB55F93D85C" modified="2009-10-13" version="1">MLAFNGTRAWSIAGTKGGGVTIGVVGAPDRVAEAACAIRALAPDATVESGSASGAIVVVADTSVDPASIGGSSLVIAAAGDTGEAMSPRPQGVVNVASAGESGSPQQSSSYGPTVTLAAYGNDTSTAAGYVAALAAILRAGHANWPARQVVAQMAGSINPASGNQHTDQLGFGVIAPVQAASLQPLDPETLPGFDAMFPVNQPPRSGAPSTRSGPTSAANPGSASATPSSGGPTSPSGSPSVAPSSPISAPGTTDTANVWPTNPIFSTGPSNGSHAAAGSGGGSGGFNPILLFGLLVILAGGGYVLWQRRRQPRPAAVKPESEWEAPSGPRHSGYSPPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC66</accession>
    <name>C7QC66_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5655"/>
    <dbReference type="EnsemblBacteria" id="ACU74514">
        <property type="protein sequence ID" value="ACU74514"/>
        <property type="gene ID" value="Caci_5655"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5655"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116318_1_0_11"/>
    <dbReference type="OMA" id="KAHWGYD"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16554" checksum="29C8555F97C8385B" modified="2009-10-13" version="1">MSSDLTFRSARPDETDALTELVMRSKAHWGYSEEFMESCRAELTIHPDQIAPSRITVAEAGGLVVAVASLEGEPPHGELGSLFVDPDRIGKGVGRALFRHMADVARGVGIRTLMLDADPHAEPFYEAMGCVRVGVVPSGSIPGRTLNRYAFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC94</accession>
    <name>C7QC94_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5684"/>
    <dbReference type="EnsemblBacteria" id="ACU74542">
        <property type="protein sequence ID" value="ACU74542"/>
        <property type="gene ID" value="Caci_5684"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5684"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_1_1_11"/>
    <dbReference type="OMA" id="TPKKYMA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="477" mass="51628" checksum="F620EE75827ABC27" modified="2009-10-13" version="1">MTTSIAELSAQVRQLRRNDAWWKNPRWGRLLIIFALFMVLSLLTNQVQGSSSNYTLVFRNSWFSARGAQFLVGSVVVWVIAEAWRARGLTQIASQATAPVRRVRNIAALKNIWVKRGTLLAVVVIAIMLPTMGLFTLPYFQSVLSDQVGVYVLAAVGLNVVVGWAGLLDLGYIAFFAIGAYTTAILSGRLPIGADGNPEAHPPIHLNLFFAFPIAVLLTMAAGLILGAPTLRLRGDYLAIVTLGFHEIVLNIARNNPKNITGGALGATSIPTFRFNLFGIHYDWNTSDSKPYWYLAIGLIIVVVFAFRRLEHSKVGRTWTAIREDEVAAAASGVPTVKYKLMAFAIGASTSGFAGVLATAKITAITPDNFPLPLSIYILAYVIFGGMGSLTGVIVGASLMTFLPYFLQGPPSWFNGGHPVVDPKDIPMWVGAVLLVMMIFRPQGLIPSKRRAQELAQAEHGVGDADAMTETAEGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCC3</accession>
    <name>C7QCC3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5713</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5713"/>
    <dbReference type="EnsemblBacteria" id="ACU74571">
        <property type="protein sequence ID" value="ACU74571"/>
        <property type="gene ID" value="Caci_5713"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5713"/>
    <dbReference type="eggNOG" id="ENOG5033A40">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084749_2_1_11"/>
    <dbReference type="OMA" id="HTAWPYV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019051">
        <property type="entry name" value="Trp_biosyn_TM_oprn/chp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09534">
        <property type="entry name" value="Trp_oprn_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="24728" checksum="69576DB2B0F26C30" modified="2009-10-13" version="1">MAESAGAGVVPKQAAQEREPIAAAESATVDSGVDPAQAARRAGRRELTLSVLIALLGGVMTWAAAGRPWATATVGEAPNALKVAATGNNLSAAVTALGLTALAGGLALFATQRLARRLVGVLLIAAGVGAAVSAFGARGAGHAAHVLADKAAAKGFAAGAVTAHTASWWIVSALGGVLVVVAGLSALVRGATWPGMSSRYENAATRASAARTVDTGSSKDLWDALDRGEDPTDAVAARTSARTPTPGAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCD0</accession>
    <name>C7QCD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5720"/>
    <dbReference type="EnsemblBacteria" id="ACU74578">
        <property type="protein sequence ID" value="ACU74578"/>
        <property type="gene ID" value="Caci_5720"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5720"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LACLRWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="333"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="439" mass="46082" checksum="26C42F4A42A0BA1A" modified="2009-10-13" version="1">MPEDPGSRRGLRAVGQAPTAVSAWLTSPGIRRFLQAAGLENAVRRGQRRAAAHPTAVDSLFVAAILLPLSGHEYLHPSDNAAGGWFLIFGFFLPLALRRRFPCSVFAFVAAVAFGQWLWGLPMPQVDFAPLIALYAVAAHASIRRTLAAVGVMEIGAVLVAVSWSYGNGALRAFVFVSGMVTAAAVLGVNTRTRRAYFATLEERARRLEFERDQQAQLSAAAERASIAREVHDVVTHSLSVMVALTDGASYAVHTSPDRAAEAVEKASEVGRQAITDMQRVLGVLRGSAGATLAELHPQPGLAQLDTLLSEVRVAGLPVELVVSGARPDLSSGVELAVFRVVQEALTNTRKHAEPGASARVRLDFGADAIEVTVVDDGVGVSAGAMTSSTAADEAGGHGIAGMTERVAAFGGQLEAGPRGVGRGWRVHARVPVTAGEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCP8</accession>
    <name>C7QCP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-quinone oxidoreductase, E subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7687</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7687"/>
    <dbReference type="EnsemblBacteria" id="ACU76511">
        <property type="protein sequence ID" value="ACU76511"/>
        <property type="gene ID" value="Caci_7687"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7687"/>
    <dbReference type="eggNOG" id="COG1905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054537_1_0_11"/>
    <dbReference type="OMA" id="QVGVCTN"/>
    <dbReference type="OrthoDB" id="1206880at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="23993" checksum="A8FAC4DF93ACA523" modified="2009-10-13" version="1">MSDKSAYEHLAKLDGDADAIVARYPQSGSALLPLLHLVQSEEGYVSPAGIEYCAAKLGLSTAEVSAVSTFYTMYKRRPVGDYHVGVCTNTLCAVMGGDAIFATLKEHLGVGNDETTEDGKVTLEHIECNAACDFAPVMTVNWEFLDDMNPDKAVRVVDELRAGKEVHSTRGPALCTFKQAERILAGFEDTRAGAVAGGGAAGHATLAGLLVSQGRTPTGPALTTEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCX1</accession>
    <name>C7QCX1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1760"/>
    <dbReference type="EnsemblBacteria" id="ACU70681">
        <property type="protein sequence ID" value="ACU70681"/>
        <property type="gene ID" value="Caci_1760"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1760"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="IIEWRAF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="277" mass="28922" checksum="A813B385D0AFCFA1" modified="2009-10-13" version="1">MTGTAAPVDTLPAPSPVANTLAAAAGGTMTDSYLSLRAGTQARGLHGQLVQQLGRMIVAGELGADRPLVPEEIGRRFEVSRTVVRESLRVLEAKGMVTARPNVGTRIRPVPEWNLLDPDVIEWRAAGVAGLDQCRELAELRCAFEPLAAQLASGRLSEPAAARLSELAVLLKQAAANGDQPGYAKIDGEFHALLVAECPNRMVEHLARVVTGAAESAGLRRRSCGPMGDAGAAAHQRLAEEIAAGDGVAAASVMRAMLAAQLEEQSAAYGLPGQRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD61</accession>
    <name>C7QD61_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">YidE/YbjL duplication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1851"/>
    <dbReference type="EnsemblBacteria" id="ACU70771">
        <property type="protein sequence ID" value="ACU70771"/>
        <property type="gene ID" value="Caci_1851"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1851"/>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035023_2_2_11"/>
    <dbReference type="OMA" id="GPQFFAN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022457">
        <property type="entry name" value="Asp_Ala_antiprt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03802">
        <property type="entry name" value="Asp_Ala_antiprt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="9">
        <location>
            <begin position="206"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="561" mass="58463" checksum="66F63ECB0667F362" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD77</accession>
    <name>C7QD77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3768"/>
    <dbReference type="EnsemblBacteria" id="ACU72670">
        <property type="protein sequence ID" value="ACU72670"/>
        <property type="gene ID" value="Caci_3768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3768"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_1_1_11"/>
    <dbReference type="OMA" id="GPIAMVP"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16316" checksum="4CDBB7570E29CCBA" modified="2009-10-13" version="1">MHISAKADYAVRVMLELAAHGPGVVKASVVIDHQDLPRKFIEAILVELRRADLVRSHRGADGGYTLARPAAAISIGSVVRAVDGPLAEVRGLRPHETEYAGAAEHLADCWVAARAALRKVLDETSLAQVLDGRLPAHVRRLAESPEAWLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDE3</accession>
    <name>C7QDE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3837"/>
    <dbReference type="EnsemblBacteria" id="ACU72736">
        <property type="protein sequence ID" value="ACU72736"/>
        <property type="gene ID" value="Caci_3837"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3837"/>
    <dbReference type="eggNOG" id="ENOG5033H2J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2631689_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="8275" checksum="F99C72A2C1A5D48F" modified="2009-10-13" version="1">MPSVTKGAAVPSVLQPAIVCGRLAVSAGFRRGFYDALTARRDELFELADAVLCTDGAVKTLVELALAPEYQRRHGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF3</accession>
    <name>C7QDF3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792475.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3849"/>
    <dbReference type="EnsemblBacteria" id="ACU72746">
        <property type="protein sequence ID" value="ACU72746"/>
        <property type="gene ID" value="Caci_3849"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3849"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="SAGYLIH"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="26687" checksum="216D17A6E0990455" modified="2009-10-13" version="1">MDLQLHDKRALVTGSTSGIGRAIALGLAREGVAVVVHGRDAERAQATAEAIIAAGGRAAVVLGDLTDDAAAAAVAEEAAGAFGGVDILVNNAGGLGADGWSEASAEDWISLYNGNVGSAVRLIRALTPSMKANAWGRIIQIGSAANPNPIPARAAYSAAKAALANLTVSLTKELAATGITVNTVSPGPSRTDGFRDLAAGFAAHHSLGDDLEAATRRLLDGPLASPSDRLAEPEEIAALVALVASPLGASVNGANLRIDGGLIPTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN8</accession>
    <name>C7QEN8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3922"/>
    <dbReference type="EnsemblBacteria" id="ACU72808">
        <property type="protein sequence ID" value="ACU72808"/>
        <property type="gene ID" value="Caci_3922"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3922"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_803905_0_0_11"/>
    <dbReference type="OMA" id="EWTIDIT"/>
    <dbReference type="OrthoDB" id="1250972at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983088" evidence="1">
        <location>
            <begin position="42"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="56"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="35350" checksum="EE39EF493671B783" modified="2009-10-13" version="1" precursor="true">MRTQTRSTRISHAIALATAVVLGAGLLTACGSSSSSSGSGGDTVTVGVSNNIFDVPIRLADSNGYFAKQGLKVKYVTITASTGSSALQSGSVQFLNDSPTAFLSAISKGIPQTAIAANAGGNPLGLIVSTKFAKAHQLTADSTADQAAAALAGSTGGASSANTKGEASIYLKKYGVDPGKVKWVSLPSPTADNAALKSGQIDWFVTSEPAPLQIQETGDGIVVADSTKVPEWSSAQAGYGQFVVASNSYLSQHAATAKKFVTAVQQATAYMNANVVSPPVLTATQAALPGVSATALQASLRQVEWPVSEAMSPEGWTKVLAFINSLGAVSQKAVISDSDWTNKYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFN9</accession>
    <name>C7QFN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784273.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0023"/>
    <dbReference type="EnsemblBacteria" id="ACU68978">
        <property type="protein sequence ID" value="ACU68978"/>
        <property type="gene ID" value="Caci_0023"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0023"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_44_3_11"/>
    <dbReference type="OMA" id="NIIGTMR"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="22115" checksum="DB4DDFF90056D115" modified="2009-10-13" version="1">MSNRDDLLAGAKKCLLEKGYSRTTARDIAQASGVSLAAIGYHFGSKDALMNEAMFQAIGEWGDHLEEAFAKAGPNLSVQERFARVFDDVSATFDENQALWMASFELIIEIDRIPGARDMFRKAIPEARTGLANLILGIPEEDVDKDMEMGAGAVLYSLMAGLLIQRFADTGQTPTGADLARGLRQLADVLEADVLKSSDKAAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFS9</accession>
    <name>C7QFS9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70906">
        <property type="protein sequence ID" value="ACU70906"/>
        <property type="gene ID" value="Caci_1986"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1986"/>
    <dbReference type="HOGENOM" id="CLU_1451991_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="19704" checksum="279409EBB5B68C42" modified="2009-10-13" version="1">MSEAAELRLDACAGHSDRLEAHACRGACHRFRGRPRQNVARVAVHEASAAVVFAVADGESGAAEACHAAVEHLLSLLPQDRPLDFESVAYYVTEQLARSVTTLVAGVVQPDVDGPYVQLFRIGDSGAWLLDRATGACHALFEPLPHVSESVDSVAEHLTASEVLLVAISPIVPTTVCCADPHCACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG59</accession>
    <name>C7QG59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4036"/>
    <dbReference type="EnsemblBacteria" id="ACU72904">
        <property type="protein sequence ID" value="ACU72904"/>
        <property type="gene ID" value="Caci_4036"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4036"/>
    <dbReference type="eggNOG" id="ENOG5033E4D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117215_3_1_11"/>
    <dbReference type="OMA" id="RQTANEY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14811" checksum="AAF892E17E088674" modified="2009-10-13" version="1">MRRPGANLAVTRGPSRLARLREQPERGSVTLEMVLAFPLLLLILLVAQFTMFYFGSEAAHTAASQAVAVARAQGATSGSGQAQGQQILDQVAGGTLPQRSITVTRGAAEAIADVTGTVQSLIPGFHLHVSAHAAAPVEAWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG92</accession>
    <name>C7QG92_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SPDY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4072"/>
    <dbReference type="EnsemblBacteria" id="ACU72937">
        <property type="protein sequence ID" value="ACU72937"/>
        <property type="gene ID" value="Caci_4072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4072"/>
    <dbReference type="HOGENOM" id="CLU_2786260_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005523">
        <property type="entry name" value="DUF317"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03771">
        <property type="entry name" value="SPDY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPDY" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="7559" checksum="50510545A2D36131" modified="2009-10-13" version="1">MEFGPEADAPHIAPLWRIAYRNPDPYRRTENSFAAYFDGHVPSEAIAAFITALTAPSTRPTDTGNEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHH6</accession>
    <name>C7QHH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784410.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0160"/>
    <dbReference type="EnsemblBacteria" id="ACU69115">
        <property type="protein sequence ID" value="ACU69115"/>
        <property type="gene ID" value="Caci_0160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0160"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="WIRTHLE"/>
    <dbReference type="OrthoDB" id="871215at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="220"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="35524" checksum="DA65FFFFE5623A83" modified="2009-10-13" version="1">MSRRVVFLVFPRFQLLDLTGPLEVFSQADMLFSPGRQRYVTEVVALGAEPVTASDGLAVVPHRTLADAAELPIDTLVVVGGRGVRTAMTDPVYVEWVRAAAGRARRVTSVCSGTFLLAAAGLLDGRRAVTHWDSCEELAERFPEIRVEADPIFVRDDPLWTSAGVTAGVDLALALVEDDLGAEVARRIAKQLVVFVQRPGGQAQFSTQLAAQRPGRDALRETQTWIADHLDDNLSLAALARRAALSERHFSRVFRAETGMTVAAYVEAARIEAAQRLLESTRDGLDRIARTCGFGTVETMHRTFNRTIRVTPGEYRRHFSSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN6</accession>
    <name>C7QHN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786354.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2142"/>
    <dbReference type="EnsemblBacteria" id="ACU71061">
        <property type="protein sequence ID" value="ACU71061"/>
        <property type="gene ID" value="Caci_2142"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2142"/>
    <dbReference type="eggNOG" id="COG4312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066898_1_1_11"/>
    <dbReference type="OMA" id="LIAYFHM"/>
    <dbReference type="OrthoDB" id="1567592at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010296">
        <property type="entry name" value="DUF899_thioredox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05988">
        <property type="entry name" value="DUF899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="27573" checksum="BB0E36806D32ACE6" modified="2009-10-13" version="1">MTADRPPLPEVTDRQTWQAQLDELAVREKAHTREGDRLAAARRRLPMVEVDPSIPVVGAQGPVPLLDVFEGRRMLTVYYAMWHDDRAPKDQCEGCTFFTAEVQELAYLHSRDVTYAVFSQGPYELSRAYYDFLGWDVPWYSARDSAEQLLADRWFGMRVSYLREGDRVFETYWTTGRGVERAAPSYAILDETLYGRQETWEDSPEGWPKEFGVSGEQFRVEGRPTAQWVQLSAGKKEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHP8</accession>
    <name>C7QHP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786366.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2154"/>
    <dbReference type="EnsemblBacteria" id="ACU71073">
        <property type="protein sequence ID" value="ACU71073"/>
        <property type="gene ID" value="Caci_2154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2154"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040582">
        <property type="entry name" value="OB_MalK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17912">
        <property type="entry name" value="OB_MalK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="361" mass="37846" checksum="7A13857BB770A051" modified="2009-10-13" version="1">MADVRFLDATRVFHGAWRPAVDGVDIDVRDGELLVLTGPSGSGKSTLLRMLAGLEPLDRGSVLIGGKDVGRTAPDKRGVSMIFQGFALFPHQTIRENIALPLTMRKSSAKSAAARVQQVAELCGVADHLNSKPDAVGYDVRQRTTMARAIVRRPDVVCLDEPLAGSGVPLMMRGRSPIAALQRELGITTLYATCSSVDAWSIADRIAVLDSGRVQQVGAPAEVFSKPATIAVAQFLGEPGMNLVTALAEEGVARLGGLAVGLTPPQASALTGNRLVIGVRPEDLSIGAESDGIRATAVLVRDTGRDYLVTARTVVDGEESDLVVRHTNGPVPVKGESVVLGVRAGATLHLFDAGSGARLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI32</accession>
    <name>C7QI32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4213"/>
    <dbReference type="EnsemblBacteria" id="ACU73077">
        <property type="protein sequence ID" value="ACU73077"/>
        <property type="gene ID" value="Caci_4213"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4213"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030169_3_1_11"/>
    <dbReference type="OMA" id="EPHSLMI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="72"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="504" mass="55073" checksum="4532155EDAE396EF" modified="2009-10-13" version="1">MPSSTTTICTAEDIFRLGAGKAQDWTCPADRRTGDLMTALPRSAPSTQDTDAHGIVAFLDAIDGLDGTEPHSVMLLRHGQVIAEGWWTPYRRDEVKQLYSLSKSFTSTAAGFAWAEKLLDLDAPVVSYFPELDAEVTDPRSRSILVRHVATMSAGHTSEQWNRAVETDYDDPVRGFLLDPPDGTPGVTFAYSQSTTYVLGAIIQRVTGSSLLEYLRPRLFDPLGIGEAFWLQHPPGRDIGFAGLHVTTDAIARLGQLYLRGGVWEGHQLLAPEWVAEATRAQVDNSNWGGPTSDWAQGYGFQFWIARHGYRGDGAYGQFCVILPEHDVVLAWTGESDDMQAVLDAAWTHLLPAFAREGSAAADAALAQRLTGLELPFPDVDEVADGEFTIAVSALRKLERISLTARELTLHEQDGVSTRLPLITGAWPPPTGNLTARATRTDADTVTVHLQFTQAPHKLVITGDLRTNTFTAVWRTVPLMSRSITALSAIADPAGRDSLWPRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX6</accession>
    <name>C7QIX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796751.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8203"/>
    <dbReference type="EnsemblBacteria" id="ACU77026">
        <property type="protein sequence ID" value="ACU77026"/>
        <property type="gene ID" value="Caci_8203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8203"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_6_0_11"/>
    <dbReference type="OMA" id="GDEIVTM"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="96"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="48141" checksum="DA77DD30716118E3" modified="2009-10-13" version="1">MASPVDHGLVKRLRQDVGDRLAEQRRADQASRLPPMTGEDERQYARALVAQALEDHARAEITFGRTPPNAMEEEALAAAVHAALYGVGRLQPLLDDPEIENIDINGCDRVFLGFADGREAEGEPVADNDEELIELIQVLGAYSGLSSRPFDTANPQLDLRLPDGSRLSAVMDVTRRPALSIRRARLGKVFLRDLETNGTVLPEVGAFLRAAVAARKNIMIAGSTNAGKTTLLRALANEIPGHERLITVERALELGLDQFPELHPNVVAFEERLPNSEGHGAVSMAELVRRSLRMNPSRVIVGEVLGDEIVTMLNAMSQGNDGSLSTIHANSSLEVFNRISTYALQSRERLPVEASQMLIAGAINFVVFITRRNAYHRGGTLQRMVTSIREVNGIDGRVLSSEIFAEGPDGRAVAHAPIACMEDLAQVGYSGPLQTHHAPGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ59</accession>
    <name>C7QJ59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784496.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0248"/>
    <dbReference type="EnsemblBacteria" id="ACU69201">
        <property type="protein sequence ID" value="ACU69201"/>
        <property type="gene ID" value="Caci_0248"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0248"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_4_11"/>
    <dbReference type="OMA" id="LWFGQAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="440" mass="46166" checksum="FACF033470CCD654" modified="2009-10-13" version="1">MRTIINRDFTRLWYGEAVSEVGDYVFNTTLVLWIATKLGNGKSWAPVAVSGVLLSGLAATLAIAPAAGVFADRWNRKRTMLRMDAIRAVAVGGLAALAFLPAGKLPVGVWLAIIYAVVFVINAAGTFFGPSRMAVIPDVVGGPDEIARASGITQSTAALAGMIGPPLAAPLLFAGGVQWAMLINALSYVVSFTAIRPVPIPGNAPSPAAKAESGFWSEFRAVLAFFAKTRVLVVLIISACIANFGAQAMNTLDVFFATRNLHAAPKLYGLLGMAIGAGAIIGALLSTRVVRRIGTVNAVWATIGTAGVLIVAYSRQTSIWAAIPVIFLASLPIAMVNTAMEPLLIQVTPRAMLGRVFSVITPAISVTQLGSTILFGWMISSLMLHFHADVAGLHVGPIDTLFTVTGLLFVVAAIYAFVMLPRKDGVPAAEPDDEGELALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJI8</accession>
    <name>C7QJI8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786504.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2293"/>
    <dbReference type="EnsemblBacteria" id="ACU71211">
        <property type="protein sequence ID" value="ACU71211"/>
        <property type="gene ID" value="Caci_2293"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2293"/>
    <dbReference type="eggNOG" id="COG1876">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_917313_0_0_11"/>
    <dbReference type="OMA" id="CENATHD"/>
    <dbReference type="OrthoDB" id="1593541at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="VanY" evidence="3">
        <location>
            <begin position="185"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="31525" checksum="A0191FE0989F5C76" modified="2009-10-13" version="1">MEQRDQTPREPAAEDIGRAAAEAAAQAEAGDDFAHGPQADRYGSAGYREPGAARSPRRWLVIGGVTVAALAVAGTAGALAGRAHPAKHDTALNAAASSNAQSPTPPATSDQTTPTTDPTTPPAPTSTSTTPPPATAAKTPSPTPKPTPTKSPSTAPTNAPAGEGGDCENATHDTPADIAKNFSGMTRSAQTAFLAAQKDAKTAGLTFLLNSGYRSATYQQRVFDCWVAQLGSPQAARQYALPPNESAHVQGYAMDIAPPSAASWLEATKGKYGLCRRYADETWHFEYQSRYKTQGCPSLLPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU0</accession>
    <name>C7QJU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792907.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4314"/>
    <dbReference type="EnsemblBacteria" id="ACU73178">
        <property type="protein sequence ID" value="ACU73178"/>
        <property type="gene ID" value="Caci_4314"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4314"/>
    <dbReference type="eggNOG" id="ENOG5033UYF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_551739_0_0_11"/>
    <dbReference type="OrthoDB" id="1637161at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="54476" checksum="A9F02FAA8A657C82" modified="2009-10-13" version="1">MTPKGFDSAESHDQANVLPDALTILTRTSWGDLEHAQGSAGDIPAGLRRFLDDGITARTHAVAKYLEVVNHQNSIYSATTSVALYVAAHLADQRTAALEIICQDGQLRPLRAVLIDWLGLIADDVSDEMLAVGLGHGFQELPAEMRLRSARSAIFQVVVSYVNDPLVIVRTAAVTSALLLLDTPEERRRHQARLAPGVHGVLEQSDDRYHRACALDSLDIWGVDTRQLRADEPSRPYSPRLPRAWATYGGDVDDLPLWLVFRTAVADRFQTVPRGPQAASLFTDRMHLGRDDRGFWRDFSNDILHQDTCGPHTADGVPLLAAIAAADRVPPRHRFDAVELLVDIATVTERHEAECWPDPPPHADFLSEPEARVAVHAHVPELLARWGSECPAVQMALAALAVTFRTERTYPALAARLQRSVDQYPAGTDIGDYVRLILVLASGDDRETLDAVESFTDAYWRGTPREAPLRGRALHLLRQMLVKAKPSVPMTTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK32</accession>
    <name>C7QK32_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6252</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794835.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6252"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75106">
        <property type="protein sequence ID" value="ACU75106"/>
        <property type="gene ID" value="Caci_6252"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6252"/>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013093_3_2_11"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983276" description="Alpha-galactosidase" evidence="6">
        <location>
            <begin position="38"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="549"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="685"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="737" mass="78180" checksum="2A7D9FC79C1A6AF4" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK93</accession>
    <name>C7QK93_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794896.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6313"/>
    <dbReference type="EnsemblBacteria" id="ACU75167">
        <property type="protein sequence ID" value="ACU75167"/>
        <property type="gene ID" value="Caci_6313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6313"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_11"/>
    <dbReference type="OMA" id="LWYPSTM"/>
    <dbReference type="OrthoDB" id="1361074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="79"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="34047" checksum="3C00E985BE4B03F0" modified="2009-10-13" version="1">MPLDPIIERVRDYRVETGFTPLYTMTIEEARKADAETEATAWTWHEHPDEIFDVTIPGPAGGQQLRVYRPHSETPLPVLMYFFGGGWVVGSLETSDAICRALAAMTPCTVVSAGYRLAPEHPFPAAVDDCYAAVKWVAEHADQLGADGSRMAVGGDSSGGNLAAAMTLMAKDDDEGPAIAAQVLVYPPFRAYADTKSMRENKDPMFFNAYSSEWFWDVYLADRAAGESPLASPLNAADHSELPAALVMTAEYCPLSDEGQDYVDVLFRAGVPVEHHHYKDLTHGFLALSSILETARDAMGLIADFLRRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK95</accession>
    <name>C7QK95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794898.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6315"/>
    <dbReference type="EnsemblBacteria" id="ACU75169">
        <property type="protein sequence ID" value="ACU75169"/>
        <property type="gene ID" value="Caci_6315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6315"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_1_0_11"/>
    <dbReference type="OMA" id="GTQRLDW"/>
    <dbReference type="OrthoDB" id="1374795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="23325" checksum="C2F92B02B77BACA6" modified="2009-10-13" version="1">MSHAPWNQSASTLLENEYVELHPVSEADREPLRRIAFDDRIWKYFVSRVQDDADFAAFFDTMLADQSSGKRACYVVVDKGTGEVAGSSSYGNLSEADRRLEIGWSWLGVDYQGKGVNRWVKYLLLQHAFDVLEAERVEFKTDVLNAQARAGLRNVGAFEEGVLRSFNPMPEGRRRDAIYYSVLRAEWPTVQEQLRRLGKAVNPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKF1</accession>
    <name>C7QKF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796775.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8227"/>
    <dbReference type="EnsemblBacteria" id="ACU77050">
        <property type="protein sequence ID" value="ACU77050"/>
        <property type="gene ID" value="Caci_8227"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8227"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074072_0_0_11"/>
    <dbReference type="OMA" id="QRRNAQY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="17674" checksum="DFF1F4123DE578B0" modified="2009-10-13" version="1">MPPNPLGALPIGPLGEYIREQRRNAEYSVRQLAQAAGVSNPYLSQIERGLRKPSAEILQQLAKALRISAETLYVRAGLLDGGADVDEDAATDGHGVRSAVADDPWLNARQKRALLDIYEAFRIESARDAAASAPDDEAANPDKSGKSDKTDETIHGPVTSGPTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM1</accession>
    <name>C7QKM1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796845.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8297"/>
    <dbReference type="EnsemblBacteria" id="ACU77120">
        <property type="protein sequence ID" value="ACU77120"/>
        <property type="gene ID" value="Caci_8297"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8297"/>
    <dbReference type="eggNOG" id="ENOG502Z8K6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038805_0_0_11"/>
    <dbReference type="OMA" id="CDREHHR"/>
    <dbReference type="OrthoDB" id="827116at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="509" mass="56363" checksum="900EA78BAD241DE4" modified="2009-10-13" version="1">MSTAQQEPPQYRRAYLLGKAKPSALIGRNRETGEIGVIVVCCAISLLSGFFVPTTFLKVLGILAGPVLALVVVFMPYNGRTIYKWFEINRSYKRLLRSPQATWRSRAMEAGTRIDGGEVEIGPPPGVGRLRWLRAQFGPDEIAVLMHLDRRTVTATLEIEGPGVGSRDSEDQETLVDRFGTLLRHVANGDGFVTRLQMLARTLPADPDAHAKDVARRGDENSPRWLQESYEHLLSMVSTSSEQHRAYLVACMPYTKDLASEAYVIGRGAVDVGLGIIMARELADICARLADADIKVRQPLGPVALSSLIHSMYDPDHPIDHLHAMSRRNAWPAELDATHPQFLRAKTRESVTAEPWCHATAWIKEWPLTPVGVNFLAPLLVHTPDVIRTVGVTMDLEPTDVAIERMLTEKINTDAEASRQAKLGRVDDPRERAHAGRVDQRGEDLASGAAGVNLVGYITVSARGPESLNRDKRTIRASAGKSFLKLEWCDREHHRAFTNTLPFATGLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVU4</accession>
    <name>C7PVU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786629.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2418"/>
    <dbReference type="EnsemblBacteria" id="ACU71336">
        <property type="protein sequence ID" value="ACU71336"/>
        <property type="gene ID" value="Caci_2418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2418"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_3_1_11"/>
    <dbReference type="OMA" id="QMYYPIA"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981314" evidence="2">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="46542" checksum="869A3A5293BCDBEE" modified="2009-10-13" version="1" precursor="true">MRKRITAAAGLAALALTATACAGGGTSTPKSDGGSSAKSTGSGTELAVPAGPVTITFEEAMTIGTLKPAMDKLVSDFQAKYPNITVKLQGEPDYATMYTKEKAEVQAGNAPTIGQAYESWASYFQSSGVLAPISDLAGTDTPPAMSTFYKGIQADMKLPDGKTWMWPFNKSVLILFYNADLMAKDGQSEPKTWDDYASVMKAVSKDGVTGSTVDPGSAKAAQYGTQWFEILAKANGATLYDADGTPHLNDPGVVKALQYMKDLKDANALATGTNYPGETALGAQKGMFDISSAAGYGFENKTVGGKFKLGISALPSGPAGAVNQLTGTNIVVFKSASADQKAAAWAFLKFITSPAEQAQWAATSGYLPVTSQALSDPVLQAFVAKNPYETAAVSELDTAFTLPGFSWIFQCQGYEATAIQEALENGKQPSDALNTAQSACAAAKAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ5</accession>
    <name>C7PVZ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2469"/>
    <dbReference type="EnsemblBacteria" id="ACU71387">
        <property type="protein sequence ID" value="ACU71387"/>
        <property type="gene ID" value="Caci_2469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2469"/>
    <dbReference type="HOGENOM" id="CLU_1792988_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046151">
        <property type="entry name" value="DUF6153"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19650">
        <property type="entry name" value="DUF6153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980401" evidence="2">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15502" checksum="2CE5EC41DF1C9D15" modified="2009-10-13" version="1" precursor="true">MARRTGRQRVMLLFAVLAGLFLMHGLSAPSMHCMPISMQTPTSMAMPITAPVSAPADSVMPPEAQIPSTLSASDGMSDHMQADPTCVPLRPEGMAALFLALFLLVIAPWRPGLPFLALLIHPRWPHGPPRTGAQVLRTLSISRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWE6</accession>
    <name>C7PWE6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6372"/>
    <dbReference type="EnsemblBacteria" id="ACU75226">
        <property type="protein sequence ID" value="ACU75226"/>
        <property type="gene ID" value="Caci_6372"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6372"/>
    <dbReference type="eggNOG" id="ENOG502Z8MJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074815_0_0_11"/>
    <dbReference type="OMA" id="YEVWRQR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012964">
        <property type="entry name" value="DUF1702"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08012">
        <property type="entry name" value="DUF1702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="36288" checksum="B9B6D7C333EAF761" modified="2009-10-13" version="1">MAATWAALRRRILTPNPAQTQLDKRGFHEKNPQARERLETVGAMFLRGYAFAAEARTADDATHRLETDVPTDYRGFAYEGAGMGFAIRDTLRPARSALLPSFLEGGGRPHKYMIYVGVGWAMARLPRPLWRKATASTSDPLLRWLVLDGYGFHQAYFHTRKYVDEHYQNPNFPWPTDGPSAYANRVIDQGIGRAMWFVCGTDPYLLAERIATFPEERRADLFSGSGLAATYAGSVDRDELLAYRELAGDYLPQVGQASAFAAAARVQTGLVSAHTELATELLCGATPEQAERVCMGSMPAAGTTDSEPLYEVWRRNISAGLAALSQTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT4</accession>
    <name>C7PWT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77191">
        <property type="protein sequence ID" value="ACU77191"/>
        <property type="gene ID" value="Caci_8368"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8368"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_2_0_11"/>
    <dbReference type="OMA" id="HERSEGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31062" checksum="7FF8CAB3B29EC72A" modified="2009-10-13" version="1">MRGRLAPEDVGLRSVGRRRTPGLRRQEVAELAAVSIDWYIRLEQGRAGAPGSAVLDALAEALRLSPVEREYLHLTARGEAPPRPLLDQRGGVTTSLRAILDGMPMLPAYVVDHSFDILAHNAAATAMFGDGFGHGTASNVALLLFLDPDARRGQLNWEQIARETVGALRANAAKYPDDPRMQAVIARLRAGHRDFAAWWGDHTVGERCSGVKRVAHPAAGVLTVSYDMFSAPEASEQRLMVLTPVDAESEVRLRGLVTAHSRRVAREAGDESGVGEAEKVEKAAVLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXH1</accession>
    <name>C7PXH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786717.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2506"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71424">
        <property type="protein sequence ID" value="ACU71424"/>
        <property type="gene ID" value="Caci_2506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2506"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_365505_0_0_11"/>
    <dbReference type="OrthoDB" id="61917at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="203"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="774" mass="82555" checksum="EC62EF1A466B1E7E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI4</accession>
    <name>C7PXI4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2519"/>
    <dbReference type="EnsemblBacteria" id="ACU71437">
        <property type="protein sequence ID" value="ACU71437"/>
        <property type="gene ID" value="Caci_2519"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2519"/>
    <dbReference type="eggNOG" id="COG1576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_2_1_11"/>
    <dbReference type="OMA" id="THGWDLA"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="19569" checksum="807B420B47A8C26A" modified="2009-10-13" version="1">MTELSTAFDSTMAILQKVGRDDLGTPTPCASWDVRGLVNHFIGSARWWASMVSGDHGLEAPEGADYAAGDFVAAYEESIRVTLGAFTAEGAADRMVSVPFGDFTGSALRAFAALDQFTHGWDLARALGYDTDLAPELASTLLAMAEVAVDDSLRGADGEAPFEAARQAPEGSCAADRLAAYLGRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN4</accession>
    <name>C7PXN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786780.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2569"/>
    <dbReference type="EnsemblBacteria" id="ACU71487">
        <property type="protein sequence ID" value="ACU71487"/>
        <property type="gene ID" value="Caci_2569"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2569"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_401547_0_0_11"/>
    <dbReference type="OMA" id="WANHHRI"/>
    <dbReference type="OrthoDB" id="941197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015020">
        <property type="entry name" value="DUF1906"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08924">
        <property type="entry name" value="DUF1906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982291" evidence="2">
        <location>
            <begin position="32"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="685" mass="72003" checksum="3C5D8456C6124BD1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN7</accession>
    <name>C7PXN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2572"/>
    <dbReference type="EnsemblBacteria" id="ACU71490">
        <property type="protein sequence ID" value="ACU71490"/>
        <property type="gene ID" value="Caci_2572"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2572"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="ADADEQY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="4">
        <location>
            <begin position="98"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1011" mass="108165" checksum="9DE2677F20903EFA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY2</accession>
    <name>C7PXY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4580"/>
    <dbReference type="EnsemblBacteria" id="ACU73442">
        <property type="protein sequence ID" value="ACU73442"/>
        <property type="gene ID" value="Caci_4580"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4580"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_34_3_11"/>
    <dbReference type="OMA" id="MSFNYVV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="19"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="47718" checksum="1661DFCCFC4F668C" modified="2009-10-13" version="1">MSGADPIGQRTRAEPQAAAATPLPRALLLIGVVMAVVGSVGGPLITSVATTLHVSLAAAQWTLTVSLLTGAVATPVLGRLGSGARRRPVVLGTLGVIVVGSVLTVLPLPLGPLLVGRAAQGCGLALGPLMMASAREHLDKARAASTIAMISVASTAGVGFGYPLAGYLTDVGGIRLAYAAALGLSAVAFLVAFRFFPASQQPVAPAPDAAASLLLTAGVLVLLLVLGEASLWQDHLAVAVGGVVAALLLVAWTLRERALVNPLVDLRLLRHRAVAGANAAMLVAGVGMYLLLSCITRYVQTPRVAGYGFGLSTFTAGLFLVPFSVVGFVAGRLSPRVRRYLSAPALVTAATAVVIGAFALFAVARGSIAGPLVSMTLLGLGVGAFSAAMPAVILEVTPAQETASAMGVNQVVRSIGFSLGSTLSALLLAAHTPAGAVFPTDEGFTVTAWIGAAVTAIALGISFTLRPESEPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY50</accession>
    <name>C7PY50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793239.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4649"/>
    <dbReference type="EnsemblBacteria" id="ACU73510">
        <property type="protein sequence ID" value="ACU73510"/>
        <property type="gene ID" value="Caci_4649"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4649"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_1_11"/>
    <dbReference type="OMA" id="SWIEGAY"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="19643" checksum="040A4570122526E1" modified="2009-10-13" version="1">MGEKGTQTRDSLLDATQDLIETAGYFGTGLNTVIAAAGAPRGSLYFHFPGGKDQLVTEALRRGGQEVSALMREVAEAAPDTAAAVTGLLDALADRLEASSWRKGCPVATVALDISASSDTLREVCSDIYRSWESALAARLSADGHPTPDDTATAILALIEGALLLARVHQQREPLERVKRVVATLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYF6</accession>
    <name>C7PYF6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795175.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6600"/>
    <dbReference type="EnsemblBacteria" id="ACU75446">
        <property type="protein sequence ID" value="ACU75446"/>
        <property type="gene ID" value="Caci_6600"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6600"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020854_4_2_11"/>
    <dbReference type="OMA" id="RIEPSRW"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="490" mass="52110" checksum="DF943960FE9B5BEE" modified="2009-10-13" version="1">MTSMDVPLEGAGGRRRAAVAKAVAKPRLTWLTLAFMTTSSVASLRASPTMAVYGLACIFLYVVPAIVFLLPTALVSAELASGWDGGVYNWVAQGLSKRLGFLAVWCQFAMTIFYYPTLLGYVASTIAYVINPQLADNGLYTAIVIMVVYWSGVWISSRGTSGVGGMASFGLIIGTLIPGVLLVVLGIVFLGQGNPSAAPMNAGSIFPQWTGVASLVLIVNNFLSYSGMEMNAVHVSSLKNPGKEFPKSMFLAMGLVLLIFILPALAISWVVPSAQLSLTAGVMQAFDAFFQYFSIGWLTPLVAVGLVAASVGGMLTWLAGPSKGLLMISRQEGYLPPYLQKLNKNGVQQNILVAQGAVTTLIALMYALIPSVSGAYWIFSVITTQVYLIMYLLMFVAAMRLRKLQPDHPRGFRAPLLGPLCVMGLLASAAAMVIGFVPSSQFGSGSVWSYVLIIAGGLLLLGFLIPFGFLKARKPSWRRADGEPAAEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYG6</accession>
    <name>C7PYG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795185.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6610"/>
    <dbReference type="EnsemblBacteria" id="ACU75456">
        <property type="protein sequence ID" value="ACU75456"/>
        <property type="gene ID" value="Caci_6610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6610"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_3_11"/>
    <dbReference type="OMA" id="CCRNFGT"/>
    <dbReference type="OrthoDB" id="787596at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027399">
        <property type="entry name" value="ADH_N_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13823">
        <property type="entry name" value="ADH_N_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N_assoc" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="26"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="189"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="394" mass="42253" checksum="53F43D57EE3DB74C" modified="2009-10-13" version="1">MKALTWHGKRNVRVETVPDPAIEDPTDVIVKVTSTGLCGSDLHLYEVLGPFLSRGDILGHEPMGTVAEVGSEVTSLQVGDRVVVPFNVSCGTCFMCRTGLHSQCETTQVREYGSGASLFGYTKLYGQVPGGQAELLRVPFGDHLPIKVPHGPPDDRFVFLSDVLPTAWQAVQYAAVPRGGSLVVLGLGPIGDMCTRIAQHLGADLVIGVDLVPERLARARTRGVRVLDLQVHGKKLADDIRDLTGGRGPDAVIDAVGLEAHGAPATKLAQQATALLPSALSAKLMQVVGVDRLTALHLAIDVVRRGGTISVVGVYGGMTDPMPLMTMFDKQIQLRMGQANVRRWSDDILPLLTDEDPLGVDSFATHHLPLDQAPAAYEMFQKKEDGAVKILFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYS3</accession>
    <name>C7PYS3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8576"/>
    <dbReference type="EnsemblBacteria" id="ACU77395">
        <property type="protein sequence ID" value="ACU77395"/>
        <property type="gene ID" value="Caci_8576"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8576"/>
    <dbReference type="eggNOG" id="ENOG50338MW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1701069_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043993">
        <property type="entry name" value="T4SS_pilin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18895">
        <property type="entry name" value="T4SS_pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982337" evidence="2">
        <location>
            <begin position="29"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="15462" checksum="1AFF42810225F712" modified="2009-10-13" version="1" precursor="true">MRRQLRNAIALSLGALAAATIGMAPAMADSSPRSDVTTINAPAGTHRALAEVAPFPGTRADAAASDDAAAGTTPAKPLTLNEVMDNVRTWIIGLLSGLATVFVTVGGLRYLMAGGNEGEVMKAKGALRSAACGYGLAVLAPVLVDALKSMVGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYU1</accession>
    <name>C7PYU1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797138.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8594"/>
    <dbReference type="EnsemblBacteria" id="ACU77413">
        <property type="protein sequence ID" value="ACU77413"/>
        <property type="gene ID" value="Caci_8594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8594"/>
    <dbReference type="eggNOG" id="ENOG5032ZM5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135445_0_1_11"/>
    <dbReference type="OrthoDB" id="2027351at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Tad" evidence="2">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14262" checksum="6C1091B02533EB9A" modified="2009-10-13" version="1" precursor="true">MIDLRRDDGSATAFVVVIVPALLLVAGLVLDLGLAMNARVHALAVAEEAARTGAGALDPVELRHGGRPSLDPTRAEAAARSYLAGAGEGGTVSASANLVTVTVKLQQPTELLRLIGLKSFSIAGTATAVPAMSIANPAGSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ03</accession>
    <name>C7PZ03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulatory protein DeoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784854.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0623"/>
    <dbReference type="EnsemblBacteria" id="ACU69559">
        <property type="protein sequence ID" value="ACU69559"/>
        <property type="gene ID" value="Caci_0623"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0623"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_15_0_11"/>
    <dbReference type="OMA" id="DYIFPRI"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="354" mass="37705" checksum="0AE3B20324DBBCBA" modified="2009-10-13" version="1">MLAARRHALILRLARERGSVQVAELVGILGVSDVTVRRDLDQLAKAGQLDKVHGGAVLPASAEPAPPARHQDPGGEGDLPVIGALIPKSSYYFNRVVDGMRRVLREPEGRLLVAVSDYQSGQDLSLAMGLVDSGAQAVLLAPADEVEWAGALGVPTVLVERRSYGPAAATTSWVRTDHETGAGLAVRHLHELGHRRIAMFARGETPTSRSVLNGFEQAASALALPQMPRIIGTDLAGWPNWGAEQIDALAERLRASEATALLVHSDEDALALLQNGFATRFAVPREMSIVAYDDEFSALTRPALTAVSPPKESVGELAVRTLLDLVRDPGAPARHVDVSPRLIVRESTGVARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP9</accession>
    <name>C7PZP9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4703</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4703"/>
    <dbReference type="EnsemblBacteria" id="ACU73564">
        <property type="protein sequence ID" value="ACU73564"/>
        <property type="gene ID" value="Caci_4703"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4703"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_2_11"/>
    <dbReference type="OMA" id="ILVIDRH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="14"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="265"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="57458" checksum="DB48D31CA182FD7D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0M3</accession>
    <name>C7Q0M3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69651">
        <property type="protein sequence ID" value="ACU69651"/>
        <property type="gene ID" value="Caci_0716"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0716"/>
    <dbReference type="HOGENOM" id="CLU_2932779_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6585" checksum="9F0E78DC7EAB6F49" modified="2009-10-13" version="1">MPNEKLAGTTEQKREIFDSIDHHAYLDAIGEALPAPATDSWLELMNGYVEVEPGDSARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0T5</accession>
    <name>C7Q0T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0778"/>
    <dbReference type="EnsemblBacteria" id="ACU69713">
        <property type="protein sequence ID" value="ACU69713"/>
        <property type="gene ID" value="Caci_0778"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0778"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030803_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="506" mass="55229" checksum="831CA3B0A575836E" modified="2009-10-13" version="1">MFHDKLHHRSAASMGVSMGFGKYGRRVAAKAKREVTGMFRAKPYDPGHPAPPARDVAPAEGVSAAGEPVWSPKSGGTCASSDVEGRVRVYASANSVNRGSGSGNGIDFMVSVNPPQPFTIEVFRVGAEDVSVLKTDALDGVTQEWSALDLSTRTITCSWTPTWHLDVPADWRSGIHVAKLRTADGLQTCVPFVVRDDAGEHDILVALPFPTYQAYNEYPKDKKTGASLYYAWEDGKIYTEGKAATKVSFDRPYHVTGLPANFDLDTAFAKWVEIWAAAHGKSVGYADSADLHDGTVDPTRHKALIFPGHDEYWSAQMRDALDKALANGAHVAFLAANNVYWRIRLEDGGRTVVCYKNRPDPGAASANERTAQWRQTGRPEQEVLGAQYVSTLKGTAPLVVDNAGHWFWEGTGVRNGERIPELLWGECDQVQPWVQSPDGFEILAASPYTGQGQPRMQHSVLHRTPAGGLVFDGGTFHWSKGLSTHGIADSRIQRATANLLSRMLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q135</accession>
    <name>C7Q135_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2797"/>
    <dbReference type="EnsemblBacteria" id="ACU71710">
        <property type="protein sequence ID" value="ACU71710"/>
        <property type="gene ID" value="Caci_2797"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2797"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_76_11"/>
    <dbReference type="OMA" id="ETNRGVM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="229"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="462"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="160"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="583" mass="62795" checksum="29B9B1CCB795631B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q175</accession>
    <name>C7Q175_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2841"/>
    <dbReference type="EnsemblBacteria" id="ACU71750">
        <property type="protein sequence ID" value="ACU71750"/>
        <property type="gene ID" value="Caci_2841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2841"/>
    <dbReference type="eggNOG" id="ENOG502ZXG6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2421560_0_0_11"/>
    <dbReference type="OrthoDB" id="1932599at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="10226" checksum="7A805E0E3D32F995" modified="2009-10-13" version="1">MNMIHTPQGMRIAPVGPAAAYKTYALSSPLATHFREATCDEVNCQAQANGWRTTIDESTELGQRQAYYIRSQSGRSFREERLPDGLTRVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q192</accession>
    <name>C7Q192_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787060.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2858"/>
    <dbReference type="EnsemblBacteria" id="ACU71767">
        <property type="protein sequence ID" value="ACU71767"/>
        <property type="gene ID" value="Caci_2858"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2858"/>
    <dbReference type="HOGENOM" id="CLU_1335541_0_0_11"/>
    <dbReference type="OrthoDB" id="196825at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="22267" checksum="D169D44FB6DBCD47" modified="2009-10-13" version="1">MADTHTVYASIGNSDDKLTQARWSEFHGKFTAAVRSHSLRIYGDWTSPGADPWQNACVAFEIGSETTARLRRDLAELAAEYDQGSIAWAEAETQFIGPTTPASVVGAAPSTLADDVLDWAREHPWTGDLIPAGDLTIEQDRDGTVRIVEAPEVIAVDIALLRHHGLAGVAYADGVLAIDTESGALRYRLLYAIDPGFVIVFRRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1J6</accession>
    <name>C7Q1J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793454.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4865"/>
    <dbReference type="EnsemblBacteria" id="ACU73725">
        <property type="protein sequence ID" value="ACU73725"/>
        <property type="gene ID" value="Caci_4865"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4865"/>
    <dbReference type="eggNOG" id="COG1387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069822_0_0_11"/>
    <dbReference type="OMA" id="HEYCALT"/>
    <dbReference type="OrthoDB" id="1615112at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017078">
        <property type="entry name" value="UCP036978_PHPhdr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036978">
        <property type="entry name" value="UCP036978_PHPhdr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="96"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35856" checksum="06DE72042447A233" modified="2009-10-13" version="1">MDPVEALRRIAFLLEWRGASPYRVRAFHTAAEAVHGLPAGPIDADDVQELQGVGPVTAEVIAQASTGAVPAYLVRLMTDAGPEAEAGWDLAMAGKGDCHLHSDWSDGGSPIEEMAEAARALGHRWAVLTDHSPRLTIAHGLSPERLRRQLDVVAEVNARQDSGFRLLTGIECDILDDGSLDQEEELLDRLDVVVASVHSKLRSEPEAMTARMVAAVSNPHVDVLGHCTGRIVTGRGRPQSRFDAQAVFAACARAGTAVEINCRPERRDPPDDLLAQAAEAGCLFAVDTDAHAPDQLSWQSSGYARAARAGLEAERLVTTWSLERLRDWTKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S1</accession>
    <name>C7Q1S1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3'-5' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795351.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6780"/>
    <dbReference type="EnsemblBacteria" id="ACU75622">
        <property type="protein sequence ID" value="ACU75622"/>
        <property type="gene ID" value="Caci_6780"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6780"/>
    <dbReference type="eggNOG" id="COG0349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042387_3_0_11"/>
    <dbReference type="OMA" id="FMRVDTF"/>
    <dbReference type="OrthoDB" id="1462689at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041605">
        <property type="entry name" value="Exo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18305">
        <property type="entry name" value="DNA_pol_A_exoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="2">
        <location>
            <begin position="253"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="443" mass="47120" checksum="36A4E9E5D4324CDC" modified="2009-10-13" version="1">MTSSSTPGGPASPEQTPKAAEAPTGLVPLLEPREGLPPVTDTEQALAAAVEALAAGTGPVAVDAERASGYKYSQRAYLVQIRRQGAGTFLIDPIACPDLSALAGDGPALAGAEWVLHAASQDLACLAEVGMHPPARRPDGTGGLFDTELGARLGGHERVGLGPLVAEVLKLELEKGHSASDWSTRPLPEAWLRYAALDVEVLVEVRDIIEDELRGAGKLDWARQEFDAVASAPPPKPRAEPWRRTSGLHKVRRPRQLAVVRALWESRDELARRRDMTPTRVLPDQAIIDSALSLPGTAAQMRTIPGFTGRMRSNDVPRYFEALTQARQLKDSELPKPGAAPSDGPPPVRAWADKDPAAAERLTAAREAVGALAAQHSLPVENLLAPDSLRRLCWTPPAPDPSDEQVSAFLAGAGARPWQVALTTHTIGEVLRRVAARAVSAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q277</accession>
    <name>C7Q277_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797338.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8801"/>
    <dbReference type="EnsemblBacteria" id="ACU77614">
        <property type="protein sequence ID" value="ACU77614"/>
        <property type="gene ID" value="Caci_8801"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8801"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_1_11"/>
    <dbReference type="OMA" id="FNNAGCG"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="61"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="44103" checksum="32CD48156897118F" modified="2009-10-13" version="1">MNGHDSATSIAPEALLDVAELRAETPGCAEVIHFNNAGCGLIAAPVLRPVLEHLALEARIGGYEAAARQADAVADFYAATASIIGAAPRNIAFASSATHAFATGVSAIPFEPGDVIVTTRNDFISQQIAFLSLRKRFGVQIVHAPDAPEGGVDVAAMADLLRRHRPRLVAATHIPTNSGLVQPVAEIGRHCRELELLYLVDACQSVGQVPVDVEAIGCDLLTATCRKYLRGPRGSGFLYLSDRVLSAGYEPLFIDMYGSRWVAPDAYQPAETAARFEDWEFPYATVLGCAAAARYAERVGVEASGARALALAANLRTRLRAIPGIRVLEQGAVLGALVTFTIQGWQPQPFKAAMDARGINSALSFREFAVFDFGDKDVDWCLRLSPHYYNTEEEVAVVAAAVAELATPAGSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q287</accession>
    <name>C7Q287_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77624">
        <property type="protein sequence ID" value="ACU77624"/>
        <property type="gene ID" value="Caci_8811"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8811"/>
    <dbReference type="HOGENOM" id="CLU_1445228_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982804" evidence="1">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="18286" checksum="244207C331821D7E" modified="2009-10-13" version="1" precursor="true">MPSPRPATIVAIAALALTVSATSSACGGDSTPPPLAPVATGSTSAGGATASAQGFVVPGVPDPCALLSADQVVQIAHLPDGVKSGAIASTSGGRSCAYNAGHPDTVTISLTAVTKSGFDAFRATIPAGTVTAIPNLGDEAYRSTQTPGVIDVYKHGFDLNIAVIHADSYASATDDAKAVALAAVGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2G5</accession>
    <name>C7Q2G5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785102.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0874"/>
    <dbReference type="EnsemblBacteria" id="ACU69807">
        <property type="protein sequence ID" value="ACU69807"/>
        <property type="gene ID" value="Caci_0874"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0874"/>
    <dbReference type="eggNOG" id="COG4848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048417_0_0_11"/>
    <dbReference type="OMA" id="AYWTSHL"/>
    <dbReference type="OrthoDB" id="1244918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="43605" checksum="EEB0DFED7F2C0FF4" modified="2009-10-13" version="1">MWRKRGTSNRDEFGHEVAERIRAASPESDVEYSASDFTVAVKPRSGTGAGGVLSLKRFFAEREGLDEDGRRAQIDRLVAIVTAPSVPEGWAEVRPMLMPVPRRADFGLADGRDPLLSRPFAPCLSELVVVDQKDRMGYVKASDPAQWGVTADDVFEAAHANLTAQFSDILDRRTDAPSATSFMGAGHTYMGSLPLLDGWLATWAAGWEQRPLVFLTEFTGMLICPEPADPTELKQRLADAEQEWTRDTRSISPVAYTTDDSGRIVPYDVPADHPARAAVRRSWALLAADTYATQTKLLRSTSDDPFIAALQLFSRSDDGLTFTLATWSANQPSLLPPADWIAFAGEGDDHFFLPWDAVAAEVDLIPEPGYHPTRYLVEAWPDPKVMARLRAQAGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2I3</accession>
    <name>C7Q2I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0892"/>
    <dbReference type="EnsemblBacteria" id="ACU69825">
        <property type="protein sequence ID" value="ACU69825"/>
        <property type="gene ID" value="Caci_0892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0892"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028176_0_0_11"/>
    <dbReference type="OMA" id="THATWFT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033396">
        <property type="entry name" value="DUF5107"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17128">
        <property type="entry name" value="DUF5107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="667" mass="74730" checksum="E9D3D3F20A02ED3A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2I6</accession>
    <name>C7Q2I6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785123.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69828">
        <property type="protein sequence ID" value="ACU69828"/>
        <property type="gene ID" value="Caci_0896"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0896"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_5_2_11"/>
    <dbReference type="OMA" id="WELPMGL"/>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="69"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="23294" checksum="4563FC341C17DB1B" modified="2009-10-13" version="1">MSDPEPTPSHATPEATSGDTLRDLPHPVRSRSQWTVHGERPVYENPWIDVLLAEVELADGTRFEHHVVRTRSAAGCVVTRTEAGREEVLLIWRHRFAIDKWVWEIPSGLIEEGEDPAEAARREVEEETGWRVSDVTPLLTFHPVGGMLRTQYRLFRAIGAEHIGEPTEQNEAEKVAWIPLDEVLGLIDAGQIATSSSLVGLLRVLTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2W6</accession>
    <name>C7Q2W6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2949"/>
    <dbReference type="EnsemblBacteria" id="ACU71858">
        <property type="protein sequence ID" value="ACU71858"/>
        <property type="gene ID" value="Caci_2949"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2949"/>
    <dbReference type="HOGENOM" id="CLU_1881990_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="135" mass="15559" checksum="127021406FED9EB1" modified="2009-10-13" version="1">MGPYSVELRASSVFYLRRSATDGEMDESPEYVDQLFIEHAEVPMLRAALAQVQMHPHYAEGRWETSRFWLTTEPPHGYTPEQIEAANEPWEITRNRAAVVIAGPLWNPQMWPDGRFQVEVEYAKLNKLVEALDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q304</accession>
    <name>C7Q304_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787189.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2987"/>
    <dbReference type="EnsemblBacteria" id="ACU71896">
        <property type="protein sequence ID" value="ACU71896"/>
        <property type="gene ID" value="Caci_2987"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2987"/>
    <dbReference type="HOGENOM" id="CLU_1783389_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="16123" checksum="78C39506276FA7C3" modified="2009-10-13" version="1">MPIPTAAQILYILNNCEDLDLEALTFCVITGGSRYGVRGNKLADGEPANWYPFYPGELMVLLDPFGREPFGQGRDPSNSSVGRFETKDLDAAIALSDAIQQDPKMEPGFWEWSDGVWVRPCDQDELKQRLRQDRGAMIARVGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3M3</accession>
    <name>C7Q3M3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6957"/>
    <dbReference type="EnsemblBacteria" id="ACU75788">
        <property type="protein sequence ID" value="ACU75788"/>
        <property type="gene ID" value="Caci_6957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6957"/>
    <dbReference type="eggNOG" id="ENOG503467Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1674745_0_0_11"/>
    <dbReference type="OMA" id="VHESDNS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025851">
        <property type="entry name" value="SUKH-4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14435">
        <property type="entry name" value="SUKH-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="17022" checksum="49E6BB0A0EA928BF" modified="2009-10-13" version="1">MSAVIGMHRYPQEYVATVRAADARDYLVTTGLPEQSSIFVAAEGGELSAGGRDLLQVSDAENGGSYFIDRDSGEIMLWDGELGNLVYVNASPRQFGESVAIFEEATAGSSQDEAEEIAARLRVELETLDPSALRDETGFWQSLLMDVSIGDYADDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q412</accession>
    <name>C7Q412_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8957"/>
    <dbReference type="EnsemblBacteria" id="ACU77770">
        <property type="protein sequence ID" value="ACU77770"/>
        <property type="gene ID" value="Caci_8957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8957"/>
    <dbReference type="HOGENOM" id="CLU_215348_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="46" mass="4809" checksum="7B76D95B29712E9F" modified="2009-10-13" version="1">MPEASTDDLVLAVEQLGAAHNRHEAERSDPTGTSAGDDGENRDSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q434</accession>
    <name>C7Q434_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="10" type="ordered locus">Caci_0962</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785188.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0962"/>
    <dbReference type="EnsemblBacteria" id="ACU69894">
        <property type="protein sequence ID" value="ACU69894"/>
        <property type="gene ID" value="Caci_0962"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0962"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_11"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14647" checksum="64BF77616EB9CFF2" modified="2009-10-13" version="1">MPPQSRKAGAKAPKLRRKEKKNVAHGHAHIKSTFNNTIVSITDPQGNVIAWASSGQVGFKGSRKSTPFAAQMTAEAAARRAMEHGMKKVDVFVKGPGSGRETAIRSLQQTGLEVGSINDVTPSPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4E6</accession>
    <name>C7Q4E6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3006"/>
    <dbReference type="EnsemblBacteria" id="ACU71915">
        <property type="protein sequence ID" value="ACU71915"/>
        <property type="gene ID" value="Caci_3006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3006"/>
    <dbReference type="HOGENOM" id="CLU_1222958_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="25251" checksum="123C89F1B194D220" modified="2009-10-13" version="1">MSDPMAEERLTEIRPEIETGAWSDDPGDSRAWLIAAELLDEVDRMRAHVGPGNCGDTFRADDGTRMVCDRIAGHGVHRGDGWWWMKDHAEGRPEVTPDLAVLRQFCATWLAELAQHGWLSRRLLLADGSELDVEHLNSALDRLAKAERENEKLRAELEGHRARQREAEDALAILLAREGGSTEITQAEMVSLDRNGSFVTSWTVVGNEKLAYVTSKRKLPEGTLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Z0</accession>
    <name>C7Q4Z0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793667.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5078"/>
    <dbReference type="EnsemblBacteria" id="ACU73938">
        <property type="protein sequence ID" value="ACU73938"/>
        <property type="gene ID" value="Caci_5078"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5078"/>
    <dbReference type="HOGENOM" id="CLU_2583272_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982888" evidence="1">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="80" mass="7700" checksum="67EFB0A0F257B77B" modified="2009-10-13" version="1" precursor="true">MKTVVKRLGGLAAATGIALFMTAAPSNAAVTAGSATSAGTGTVAPNATAIEYGLVASPDATAIEYGLVVSPDATAIEYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q504</accession>
    <name>C7Q504_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793681.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5092"/>
    <dbReference type="EnsemblBacteria" id="ACU73952">
        <property type="protein sequence ID" value="ACU73952"/>
        <property type="gene ID" value="Caci_5092"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5092"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_5_11"/>
    <dbReference type="OMA" id="DAVFWLV"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="31484" checksum="2981B41C752B598A" modified="2009-10-13" version="1">MIVITAPTGNIGRRLLALLLESAPAAGEELRVIVRDPARVPDCARGRVEIVTGSHGDPDVLDQAFAGADAVFWLVPPDASLTPLDAWTTFTRPAAEALAAHGVGHAVGVSALGRGTPLADRAGLVTASLAMDDLIAGSGVAYRALANPSFFENLLEEADSIREKGFFTDTVEPDRKAPLVAVADIAAAAERLLLDRSWTSVGSVPVLGPEDLSANDLARIMTEQLGQPVRYERQPLEEMFTTLVGYGLNEEFVQGIVDMKRAKDEGLDTGVARIPGTSSPTTFEQWCAETLKPAVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q566</accession>
    <name>C7Q566_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795563.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7005"/>
    <dbReference type="EnsemblBacteria" id="ACU75835">
        <property type="protein sequence ID" value="ACU75835"/>
        <property type="gene ID" value="Caci_7005"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7005"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032284_0_0_11"/>
    <dbReference type="OMA" id="ISCRIND"/>
    <dbReference type="OrthoDB" id="1313645at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="9"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="463" mass="50358" checksum="6907EBCED668A05B" modified="2009-10-13" version="1">MPNSVPTTPLSHGQLYSWREVESYPPLWRAEANLSATWDLRGLTSERLAAALCRLVELHEPLRTSYSAGSDGVPAQHVHPLEDESRCGIDAATGLPGAIAVADRQITDFGDPIRTTETQAAQEIPMTGGPCWRGTLVTTDGAPMFLSLAFSHLIVDVWSMIELERRFRVLVEDPEADLDAGASQRDLSATQHAEKWQSRQAAAEKYWRGVLAEAPAGFLDALPTLSTGQTKPRVQAVLHSHRLTALAAEAARQHAVTVPAVLLALVTAALAERLGTEGTVVSLMSNNRFAPDQRHVVGTLNQLIPVALPVDRAGTLGEHVKRAHWASAKAYRYSCYDVDRIAALATESAAPADGWYNRLFPAWFNYLPFDDRILDPADTAPAELVWTERPREYGQPFDVRVTAQDGRTSIQLRTDPDVADAEALTGMLRTIAFGVQQAVSAPESGLKDLWTPAAPDAALFPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q567</accession>
    <name>C7Q567_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-dependent decarboxylase, exosortase system type 1 associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795564.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7006"/>
    <dbReference type="EnsemblBacteria" id="ACU75836">
        <property type="protein sequence ID" value="ACU75836"/>
        <property type="gene ID" value="Caci_7006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7006"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_0_3_11"/>
    <dbReference type="OMA" id="AKSIGCN"/>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017530">
        <property type="entry name" value="DCO2ase_PEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03099">
        <property type="entry name" value="dCO2ase_PEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="3">
        <location>
            <begin position="46"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="2">
        <location>
            <begin position="292"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="42603" checksum="2E5B24703C584D1E" modified="2009-10-13" version="1">MTLTQALAARFGRAGGALAVGGVPVERLAARVGATPFFAYDRGLLADRLAAVRHALPAGVHLSYAVKANPMPALLHHLSALVDGFDVASGLELRAALDTPVRPEKVSFAGPGKTVAEIRQAVASGVTVELESELELTRVRAAAAEIGVAARVAVRVNPDFAVRGSGMRLGGGPQQFGVDSERVPDLLRLMAGEDLEFQGFHIFAGSQNLRAEEICEAQRRTVDLVVALAEHAPSPVRYVNVGGGFGIPYTARDTALDLAPIGENLAKLTDVVAAALPGARIAVELGRYLVGEAGVYVTRVLDRKESRGKVFLVVDGGLHHQLAASGNFGQTIRRNYPLAVANRIDETAAGKVSVVGCLCTPLDLLGDDVDLPAADVGDLIVLFQAGAYGLTASPTAFLSHPAPVEVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q575</accession>
    <name>C7Q575_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795572.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7014"/>
    <dbReference type="EnsemblBacteria" id="ACU75844">
        <property type="protein sequence ID" value="ACU75844"/>
        <property type="gene ID" value="Caci_7014"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7014"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="SHANMLT"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017529">
        <property type="entry name" value="AcylCoA_ligase_PEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03098">
        <property type="entry name" value="ligase_PEP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="432"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="529" mass="56670" checksum="5200C83F76F4F35C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5I7</accession>
    <name>C7Q5I7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77798">
        <property type="protein sequence ID" value="ACU77798"/>
        <property type="gene ID" value="Caci_8985"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8985"/>
    <dbReference type="eggNOG" id="ENOG5033U65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952878_0_0_11"/>
    <dbReference type="OMA" id="PKHNPDG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="31250" checksum="AAC437A2672DB096" modified="2009-10-13" version="1">MGLCARPRAELNRPDHPRVKCIASLDRVHEDGSMQQERSWVYAACTVRLAPDQPGCEAVFDQALTNGLAAIVALEWPGAEANARGRVRSAAELLDVISERVPQDGQTGVYPIPDTSISQGLNTLVDVATLRDGVTQTQQVRHARGPGRLEERHVDALRALDHHRSLRSLSGEESDRVWDQAREDDRASILRAVAFLDLIGEDEAARRAVDVENPNAYHPKHNPDGQELEECPVCGLDTFCIQGIDDYGYGFGSGQCLVCAYVRSRDTADEMALDFHIARLSAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Q0</accession>
    <name>C7Q5Q0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ordered locus">Caci_9048</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797585.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9048"/>
    <dbReference type="EnsemblBacteria" id="ACU77861">
        <property type="protein sequence ID" value="ACU77861"/>
        <property type="gene ID" value="Caci_9048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9048"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_1_0_11"/>
    <dbReference type="OMA" id="MQGLLEC"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="103"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU77861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="32800" checksum="5B73C168E9073FA8" modified="2009-10-13" version="1">MSDLGRVVVLAGGLSHERDVSIRSGRRVADALRSAGVEVQVRDIDAALLPSLLADRPDAVFPTLHGATGEDGAVQGILALLGVPYVGSSAAACRRAFDKPSAKDAIRTAGLATPDWVAIPKTTFRDLGTHAVLDAVSAALPMPLFVKPARGGSSLGAAAVHTREDLPSAMVACFAYDETALIERHITGREIAVSVVDTGTGPQALPAVEIVADSGVYDYAARYTAGITEFFAPARLTAEEAKSVEQLAVRAHTTLDLSCVSRTDLILDADGIPWFLEVNVAPGLTETSLLPLAAGAADLDLGVLYRDLVQAVIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5U5</accession>
    <name>C7Q5U5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70042">
        <property type="protein sequence ID" value="ACU70042"/>
        <property type="gene ID" value="Caci_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1116"/>
    <dbReference type="HOGENOM" id="CLU_833400_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="34967" checksum="34A0D61F10FD3BD9" modified="2009-10-13" version="1">MPVGQAAPVAAKPVRESVVVPRQAAAMPELAGQRHAVARPVRKMALVAAKQVLESVLVRRTVATPHRHEAANRARERAVCRKAAARLEPAVVWLRTDAPRRHEAANTARERAACRKAAARRVRQMALHAAGLRAVAARPELAVVRRLIAAMRRRREAAAAIAGSELPPAVAARPVRWAALDTAGRVVVVAMRAAVASPGSESARVGARKAADAAAGRGPSRFRFRMGSPGGVDTGAGRVGSCSPPWRAELLLLCAKGRAVVVAATRLLGEGVCRSRGAWALGALGPLRRAGGGLASAIRGCGCACGWDGPRLRPVLICVHRVRWGERSSRPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q631</accession>
    <name>C7Q631_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1203"/>
    <dbReference type="ESTHER" id="catad-c7q631">
        <property type="family name" value="Est9X"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70128">
        <property type="protein sequence ID" value="ACU70128"/>
        <property type="gene ID" value="Caci_1203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1203"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_10_1_11"/>
    <dbReference type="OMA" id="GGWPTTF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="56"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="27824" checksum="F59B81CEB33CF276" modified="2009-10-13" version="1">MTITPAPHPYGPHPSQVADLFVPEGEGPFPVVVLIHGGFWRTPFDRELMEPLAEDLAERGFAAWNVDYRRVGDGGGGEAWRVTLDDVAASLDQLGALSGEFPLDTDRTALVGHSAGGHLALWLSSEFQVAAAVSQAGVANLYDAAAERLGVGSPREGLGVLDVPATMEFLGGGPEQVPDRYAAASPSALLPLETPLLLIHGDEDDRVPISQSRNFADAARESGDEVEVAEFPGMGHFEVLDPKHASWGRTIDFLERVLAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B4</accession>
    <name>C7Q6B4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787413.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3213"/>
    <dbReference type="EnsemblBacteria" id="ACU72120">
        <property type="protein sequence ID" value="ACU72120"/>
        <property type="gene ID" value="Caci_3213"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3213"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_15_1_11"/>
    <dbReference type="OMA" id="VHYCFES"/>
    <dbReference type="OrthoDB" id="1745184at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="21452" checksum="6FADE32AB1B58122" modified="2009-10-13" version="1">MPRIAVDERRGLLVEAAIRVMVRDGVAKATTRSIVAEAGMALAAFHYSFRSKQELLEHVIETITAHTLDLAVEVLVGDGSAEDKVRSALDTYWRHVITNPGEHRVTYELTQYALRHPGLATIARRQYEAYIAAASKLIESLDVSWKAPTPVIARYLISVMDGMTLLWLNEGDDASCRAALNLAGDHLVSLIASRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P5</accession>
    <name>C7Q6P5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5221</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793809.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5221"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74080">
        <property type="protein sequence ID" value="ACU74080"/>
        <property type="gene ID" value="Caci_5221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5221"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_13_0_11"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018905">
        <property type="entry name" value="A-galactase_NEW3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="PTHR42721"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10633">
        <property type="entry name" value="NPCBM_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980640" evidence="3">
        <location>
            <begin position="36"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="726"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1357" mass="138657" checksum="3D7DE548D998EF55" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V7</accession>
    <name>C7Q6V7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795698.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7141"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75970">
        <property type="protein sequence ID" value="ACU75970"/>
        <property type="gene ID" value="Caci_7141"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7141"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041027_0_0_11"/>
    <dbReference type="OrthoDB" id="27078at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982584" evidence="2">
        <location>
            <begin position="38"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="24"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="538" mass="54815" checksum="4297FCE9F8A5D9C2" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q726</accession>
    <name>C7Q726_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795767.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7210"/>
    <dbReference type="EnsemblBacteria" id="ACU76039">
        <property type="protein sequence ID" value="ACU76039"/>
        <property type="gene ID" value="Caci_7210"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7210"/>
    <dbReference type="eggNOG" id="ENOG5032YSE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_185993_0_0_11"/>
    <dbReference type="OMA" id="QGWSWQA"/>
    <dbReference type="OrthoDB" id="1850835at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="8700" checksum="05D8336C34CDCD4E" modified="2009-10-13" version="1">MTEATDLAAAAGSTDPREGLRAVAALGRLLDSLETLQVHHARAKGWSWQEIADELGVSKQAVHKKHAGRTRAASVPASGREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7J2</accession>
    <name>C7Q7J2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787478.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3278"/>
    <dbReference type="EnsemblBacteria" id="ACU72185">
        <property type="protein sequence ID" value="ACU72185"/>
        <property type="gene ID" value="Caci_3278"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3278"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="DYTRPGW"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="33378" checksum="1C138A400D99D27A" modified="2009-10-13" version="1">MRVIRVREFGDPSVLKLEDAPPPAAAAGQAVIDVEVAAVLFGDTIVRGGRFPFPLPYTPGLEVGGRVAAVGPGGDEALVGRRVVAVTPRTGGGYAEQAVVDTRWLFEVPDGTALDDAVPVFQAGAVALGMLGAMRLTAGETILITAAAGRLGSLLVQAAKAAGATVIGAVGSSGKTAFVTALGADAVVDYSMPDWIDQVTTATGGQGVDLALDAVGGAIGAGALAALRDGAGRLGSYGFASGEWTPLDAGVIGRRGLSVVGAAGITFAKPEAEQRADAERALSELAAGRLIPRIHAAFPLEGAPEAHAELEARSTIGAILLRPKSPYESRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U3</accession>
    <name>C7Q7U3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787579.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3380"/>
    <dbReference type="EnsemblBacteria" id="ACU72286">
        <property type="protein sequence ID" value="ACU72286"/>
        <property type="gene ID" value="Caci_3380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3380"/>
    <dbReference type="eggNOG" id="ENOG502ZKTG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_693869_0_0_11"/>
    <dbReference type="OMA" id="LRTHERW"/>
    <dbReference type="OrthoDB" id="2208359at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="41271" checksum="7E6642D36A7A6AA5" modified="2009-10-13" version="1" precursor="true">MIGLIAAALVPAAGSAAVVWDDSGSGLASVRAERRGIQYLGQTVKLLVSVAEAQSSAVRNLPTSPPDLSQAVAAVDATGLPSDPDPGAGTLWAQIRPQVLALSGTSTTGAAAYRAYGQVTDLLLQQIAAIDDASGLVPDSRADAYHLIDALTVWLPDMAVQAGRYDDQVTLAEPDGTSASASPDAARAAATAQVAMLRDRIAVDAHAFVTALNKVFRTTASATLGPHLLGDVDLVNTDINALAPTASAIDDALIVPSAPTVSEDRKAFDPAVQVLETAGLDELDKLLQAREAGYDRQRTAMAALLGGGAVVAVLSLWWLWRQRGADTRTAERATTRTPARTVARFKPSRPEPEVGTSSDTPARQAIPEEPGEQPVPAAAEPVEATDPVPLTLPERRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7V2</accession>
    <name>C7Q7V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793848.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5260"/>
    <dbReference type="EnsemblBacteria" id="ACU74119">
        <property type="protein sequence ID" value="ACU74119"/>
        <property type="gene ID" value="Caci_5260"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5260"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="IITWSMM"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="3"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="42903" checksum="94AA44D84DF1607A" modified="2009-10-13" version="1">MRIDPFTVSIPDAVLTDLRERIARTRWPDAAPGEAWSQGVEVGYLRELLEYWADGFDWRAAERSLNRYRHFTAEVDGVRVHFVHHRSDSGGDRVPLILTHGWPSTFAEMLGLVDRLGDRFDLVVPSLPGYVFSQRPARVGVDRRHVAGMWHRLMQGLGYERYGACGGDFGAGIATHMALMEPERMIGIHLSTPELAPYDGPGAAPLTPEEQAYLAQVERWEQTERGYSAVQSTRPQTLGYGLNDSPAGLAAWVLDKWRSWSDSGGDLNATFGRDSLLTMLTLWWATDSITSSMRDYYDNRWHGTPIGPQDRVRVPTAMAVFANEFVSEGQVPRAWYERLYQVERWTVFERGGHFAAMEEPELLAGDIAEFFRLLRQPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z0</accession>
    <name>C7Q7Z0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793886.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5298"/>
    <dbReference type="EnsemblBacteria" id="ACU74157">
        <property type="protein sequence ID" value="ACU74157"/>
        <property type="gene ID" value="Caci_5298"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5298"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056891_0_0_11"/>
    <dbReference type="OMA" id="HSTYDAC"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="132"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="394" mass="41858" checksum="9C2B077EE5D1D44E" modified="2009-10-13" version="1">MTDHAARMARILETHQDVVHVGGSTEALIKRDELLVLGAHADAVHEQARQWVDSREDFAELGVSRLRLRAGAGVDAADLTHSLRGGAGAHRRTSVTPNHVMSGAPNWTGGPFGAPTPAADLPAPVDAEGGGRRATIGILDTGIDPHPWFAEADWYQACTETEHEDLDPASEDDLESDSGHGTFIAGVILQHAPGTYLRVQRVLGTDGVTDELELLHGLRRLHARAAAESNRLDVLNLSLGCFTFDDRPSPVLADAFARVARHSVIVAAAGNHSSDRPYWPAALKDVVAVAALAQADTDGPERASFSNYGWWVDASAPGEKVSSSFLTHGRENGEDFHGFATWSGTSFAAPYVAGKIAALMSAKDMTARDALSELLDPANTRIPDLGVVVASDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q841</accession>
    <name>C7Q841_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74208">
        <property type="protein sequence ID" value="ACU74208"/>
        <property type="gene ID" value="Caci_5349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5349"/>
    <dbReference type="HOGENOM" id="CLU_978939_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="30881" checksum="3263D1BAD474CD59" modified="2009-10-13" version="1">MSPSQAASWRRSQCADPSQGTISHQSQCADQSMSRCARPSWRKATLSSRSPRPSTSRSSKRRPGASRRTPGARPCQRGSPRAILCASRNIVGRRSTSMSGPMSRQSVSVSQHLSVRASRWAGLSRRRSASMSGPMSRQSASVSQHLSARASRWAGLIRSLSRSTSTSGPRSSASQGLGARAILWAGLVRGLRRRRRTSRHCRVVRRAVIVRGWGGMGLGRVRGCGVVSSGLCCGRSGRWIRIGLGLGVCGMRVRRRRCRGLSLSLRMVRCRGSRRGLRLCGVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q947</accession>
    <name>C7Q947_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3461"/>
    <dbReference type="EnsemblBacteria" id="ACU72367">
        <property type="protein sequence ID" value="ACU72367"/>
        <property type="gene ID" value="Caci_3461"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3461"/>
    <dbReference type="eggNOG" id="COG5478">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158588_0_0_11"/>
    <dbReference type="OMA" id="LHEWQIA"/>
    <dbReference type="OrthoDB" id="1852102at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007251">
        <property type="entry name" value="Iron_permease_Fet4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04120">
        <property type="entry name" value="Iron_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15665" checksum="E275495E65C334C1" modified="2009-10-13" version="1">MSTQTHTPGRRAPHMPSDVTPTLSAFERFATSAARFASRPWFFAVCLLLVVVWAPSYFVVGSMDTWQLIINTITTIVTFLLVALLQNTQTRADKATQDKLNALAQGMSAMMAHLADIHDRQEINNDVAELRDAVGLEDSESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C3</accession>
    <name>C7Q9C3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793998.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5410"/>
    <dbReference type="EnsemblBacteria" id="ACU74269">
        <property type="protein sequence ID" value="ACU74269"/>
        <property type="gene ID" value="Caci_5410"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5410"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_5_0_11"/>
    <dbReference type="OMA" id="DYQVHPG"/>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="45"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="23366" checksum="84E22727F270B0CB" modified="2009-10-13" version="1">MEIRDVPEKWPVLASEEKFRGHVISIRTDTVKMVDGKVAERDYVVHPGAVGVVALDEADRVLLVRQYRHPVGWRLWELPAGLLDHPGENPLEAAKRELYEETHQQADDWRVLVDLFTTPGGSDEAIRVYLARGVREADGEQYAREHEEADMAAVWADRAEVTRLILAGELHNPLTVAGVLALTTAISTNALDDLRPADAPWRQRPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9T8</accession>
    <name>C7Q9T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7431"/>
    <dbReference type="EnsemblBacteria" id="ACU76257">
        <property type="protein sequence ID" value="ACU76257"/>
        <property type="gene ID" value="Caci_7431"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7431"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="WFQAIRN"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
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    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="533" mass="54741" checksum="690483704B813E76" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X7</accession>
    <name>C7Q9X7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796021.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7471"/>
    <dbReference type="EnsemblBacteria" id="ACU76296">
        <property type="protein sequence ID" value="ACU76296"/>
        <property type="gene ID" value="Caci_7471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7471"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070025_0_1_11"/>
    <dbReference type="OMA" id="HMRISMN"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="66"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="CMD" evidence="2">
        <location>
            <begin position="204"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="31269" checksum="9BF18F75DF7ED263" modified="2009-10-13" version="1">MSGTAPQPEHSSPTTETTQTGQPDHADHADHADRPASRYDRGLALLGQVGGTDPTRALAGLADTAPDLARLTIEFYADIYSRPGLTLPQRQIINIAALTALGTAAPQLRFHIDGALNVGVGPTEIVEVIMHMSVYAGVPATLNGLAVAKAAFADRTDLDWSPTASPIEEQESAEQRYNRGLDALQAIDGRAGDQVMASLAPISPDFARLLVGFAFADIYSRPGLDLKSRELATVAACTALGTAAAQLRVHLHGLLNVGGTREEPVEAIMQMAGYAGFPAALNGIAAAREVFAERAGAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA08</accession>
    <name>C7QA08_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HTTM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1483</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1483"/>
    <dbReference type="EnsemblBacteria" id="ACU70406">
        <property type="protein sequence ID" value="ACU70406"/>
        <property type="gene ID" value="Caci_1483"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1483"/>
    <dbReference type="eggNOG" id="COG3011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045120_0_1_11"/>
    <dbReference type="OMA" id="GSRWQDG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008488">
        <property type="term" value="F:gamma-glutamyl carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017187">
        <property type="term" value="P:peptidyl-glutamic acid carboxylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011020">
        <property type="entry name" value="HTTM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007782">
        <property type="entry name" value="VKG_COase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05090">
        <property type="entry name" value="VKG_Carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM" evidence="7">
        <location>
            <begin position="103"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="468" mass="51142" checksum="19DE920E1BA3A8E4" modified="2009-10-13" version="1">MTSGIDDPADTAETADVLGPGDVSDVSDAIDVSDAISTADAAVAAAGIGVVETTGIADATDIADTPALAVAVAVAAAQGPAFRGEPLTWVAAKAQNAFTRLTTHAVALYGTAVLRIGYGSLYLIFLLHEYPRHDALWGPNAAWTPALNQQFANDPGLDWFAIDRWWYTFLGHGGKTWFEFWYTVAILVCLLFVLGWRTRVTSICFALTIMAFTGRDVFLTDGGDNIMGLMAIYLAFSRCGTRWSLDARRKRRQAEKREARGIAEFSWPDSPGWQAVAELDRTREEIVTFLHNAAVLVIAAQICVVYAAAGLYKSQGSYWQNGTALYYTLKLDWFRPWPGLSDFMAGQSVTIAIVAYLTVFVQIAFPFAVFSKWLKYPCLVMLVGMHFSIAVVMGLPLFSAAMMVGDAVFLPTAMWLWVGRKVREQVGRLPKPGRYLFSKQARPAPAIPQSLEASALPHQAQPHKSASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAF6</accession>
    <name>C7QAF6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792184.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3550"/>
    <dbReference type="EnsemblBacteria" id="ACU72455">
        <property type="protein sequence ID" value="ACU72455"/>
        <property type="gene ID" value="Caci_3550"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3550"/>
    <dbReference type="eggNOG" id="COG2867">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049174_0_0_11"/>
    <dbReference type="OMA" id="KNWTSRR"/>
    <dbReference type="OrthoDB" id="1427617at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="35337" checksum="67F1922B6FC1DEE8" modified="2009-10-13" version="1">MTQIGLKKVEHEIMISASADAVYQLIADVENWPRIFPPTVHAERVELSGNSERIRIWATANGAAKNWTSRRVLDPALRRIEFRQEVTTAPVAAMGGTWIVETIDAEQCKVRLLHDYRAVDDDPESLKWIDEAVDRNSRSELAALKANVERIVGPNEDLLMSFEDTVRIQGELKDVYEFLNEAGLWKERLAHVARVELTEDEPGLQVLEMDTRTKDGSTHTTKSVRVCFPNNKIVYKQTTLPALMTVHTGYWLLEEAGDSVYATSQHTVVINTENIKAVLGPDAGLAQARDFVKKALSGNSGDTLGYAKDHAEARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAQ1</accession>
    <name>C7QAQ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5515</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794103.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5515"/>
    <dbReference type="EnsemblBacteria" id="ACU74374">
        <property type="protein sequence ID" value="ACU74374"/>
        <property type="gene ID" value="Caci_5515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5515"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042787_0_0_11"/>
    <dbReference type="OMA" id="AKHYWVA"/>
    <dbReference type="OrthoDB" id="957193at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024026">
        <property type="entry name" value="3'-RNA_MeTfrase_Hen1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026610">
        <property type="entry name" value="Hen1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024740">
        <property type="entry name" value="Hen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038546">
        <property type="entry name" value="Hen1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21404">
        <property type="entry name" value="PTHR21404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12623">
        <property type="entry name" value="Hen1_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04074">
        <property type="entry name" value="bacter_Hen1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hen1_L" evidence="10">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_12" evidence="9">
        <location>
            <begin position="305"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="511" mass="56006" checksum="9CCB8B9A8A204F3B" modified="2009-10-13" version="1">MLLTITATPPPGAEWPATDLGFLLHKNPDRVQAFDVTYGKAHVFYPAAGPQECTAALLLEVDPIALVRGRGRNAPDFALSQYVNDRPYAASSLLASALGNVFRTALRGRCDQRPDLAATALPLRVEVPALICREPQLAVELFEPLGWTVAAEPVALDPAFPEWGASRYTSLTLTGTLRLSEALSHLFVLLAALDGAKHYWVASDEVDKLVRAGEGWLGAHPLRGMIARRYLARRQPLVREALARLAEVDDVEPEVLDNAVGFDGEPVQESAPDAVPAKERKLSLATARREAVVETLHEAEASRVLDLGCGEGALLRDLLKDKAFTEVVGIDVSARALQIAARKLHVDRLPDRVKARLTLRQGALTYTDARLAGYDAAVLMEVIEHVDAHRLPALEHAVFRAAHPRAVVVTTPNVEYNARYETLEAGRFRHSDHRFEWTRAEFRAWAERVAAAHGYDVRFKPVGEVDPELGPSTQLALFTLAKSPTNENLTNENLTNENLTNDNPKEASADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE9</accession>
    <name>C7QBE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785820.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1605"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH87">
        <property type="family name" value="Glycoside Hydrolase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70526">
        <property type="protein sequence ID" value="ACU70526"/>
        <property type="gene ID" value="Caci_1605"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1605"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009451_0_0_11"/>
    <dbReference type="OrthoDB" id="32528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd14490">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033801">
        <property type="entry name" value="CBM6-CBM35-CBM36-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982705" evidence="2">
        <location>
            <begin position="40"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="809"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="1062"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1212" mass="121342" checksum="34C6A993C8C61D3F" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW3</accession>
    <name>C7QBW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792311.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3680"/>
    <dbReference type="EnsemblBacteria" id="ACU72582">
        <property type="protein sequence ID" value="ACU72582"/>
        <property type="gene ID" value="Caci_3680"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3680"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_1_11"/>
    <dbReference type="OMA" id="AFPITNW"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="510" mass="55250" checksum="7C75289D0AF575FE" modified="2009-10-13" version="1">MGSPELLIVLRRDRPTPLQQQVCDQVIALVRAGRLRPGDTVPASRELARQLDVSRTVIIKAYELLTANGYLTARPGSGTRVAGPEHHQGTPTVPSAAKRAVALAPRPPRPTDDGHALWQPWEPAPVLRQADPAAIDFRHGTPALSRFPTARWRQSLEAALAKADDSLFGYGPAEGSAALRAEIAALVRHSRALSAPAERIMITSGATQALDILVRAIVGPGDVVVIEDPSHTVLRQIFGFSPAAVVPVAVDDEGLRVQDIDATVRAHGHDPARVRLVYVTPSHQFPTGCVMTAQRRRALVGWAQERGATILEDDYHNEYWFSGDRLPALAADAHQGSVVYVGSFSKTLFPALRIGYAILPERLVQPFLGIKWITDRLTATVEQEALADFIATGGYARHIAKMSGLYRRRRLRLLEALYECFGAGVRISGEAAGLHVLVALPGLLEAGVGEGEFARRAAERGVLIYPASGYYAQDPPTEPTFLMGYAALTPERITEGVARLAAVRRLRAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC50</accession>
    <name>C7QC50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5639"/>
    <dbReference type="EnsemblBacteria" id="ACU74498">
        <property type="protein sequence ID" value="ACU74498"/>
        <property type="gene ID" value="Caci_5639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5639"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_0_11"/>
    <dbReference type="OMA" id="AWATSDN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="15153" checksum="416E02B99D7BE6D0" modified="2009-10-13" version="1" precursor="true">MRQLGDLEAAVMDRIWRRNRPVLVRDILDDLNTDRSLAYTTVMTVMDKLHRKGWLRRQPQGRAYVYEAVASRESYTARLMRDAWATSDNQAVAFVHFLEQLSDEEAKALRAALEICPPASPHPAPEEERMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCD5</accession>
    <name>C7QCD5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="10" type="ordered locus">Caci_5725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794312.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5725"/>
    <dbReference type="EnsemblBacteria" id="ACU74583">
        <property type="protein sequence ID" value="ACU74583"/>
        <property type="gene ID" value="Caci_5725"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5725"/>
    <dbReference type="eggNOG" id="COG0106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_1_1_11"/>
    <dbReference type="OMA" id="EWLHLVD"/>
    <dbReference type="OrthoDB" id="794219at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010188">
        <property type="entry name" value="HisA/PriA_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01919">
        <property type="entry name" value="hisA-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25030" checksum="EBAC4B865D830499" modified="2009-10-13" version="1">MPGYLELLPAVDVADGQAVRLVQGAAGSETSYGDPLTAALAWQSAGAEWIHLVDLDAAFGRGSNAELLAGVVGKLDVRVELSGGIRDDESLRRALSTGCERVNLGTAALEAPDWVRGAIAEHGEKIAVGLDVRGTTLSARGWTKDGGELFDVLARLDADGCARYVVTDVHRDGTLTGPNLQLLRDVCAATAKPVVASGGVSSLADLEALATLVPIGVEGAIVGKALYAGAFTLEEALELTRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCL5</accession>
    <name>C7QCL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796203.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76478">
        <property type="protein sequence ID" value="ACU76478"/>
        <property type="gene ID" value="Caci_7654"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7654"/>
    <dbReference type="HOGENOM" id="CLU_2664356_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="8223" checksum="182F477D74D93FDE" modified="2009-10-13" version="1">MGPIERYDVSSIEQPTKADLERLARRRLDARRRGRELVLTGVGARLRLLLAVTGLDEVFVIGGEGVPEGLPEPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCU5</accession>
    <name>C7QCU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1734"/>
    <dbReference type="EnsemblBacteria" id="ACU70655">
        <property type="protein sequence ID" value="ACU70655"/>
        <property type="gene ID" value="Caci_1734"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1734"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="RTHRAWN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20342" checksum="C751839BD417D43C" modified="2009-10-13" version="1">MATGETVREPDGFREFLAARQAHLLRAAWVLTGDVQLAEDLLQTALVKVLPRWERLARDGALEPYLRKTMINTATSWWRRRWHGEVPSGHVPSLTARRGAGWEPVGGGAEFEAIDDRSVLGAALRALPARQRAVVLLRYYLDMSEAETAVMLGCSQGTVKSQSSKALAALRGRLAPAQRAQEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF7</accession>
    <name>C7QDF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3855"/>
    <dbReference type="EnsemblBacteria" id="ACU72750">
        <property type="protein sequence ID" value="ACU72750"/>
        <property type="gene ID" value="Caci_3855"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3855"/>
    <dbReference type="HOGENOM" id="CLU_1955663_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="128" mass="13772" checksum="E95585D6ED247E31" modified="2009-10-13" version="1">MLRGKIQPGGDDCDSSGVATTGGAAERRTHLVDSRQAIQKPHDRIVAVLGAQSTPDNGGPPRFTIAIDENMPRDDKQIACRRLARIDPSLGDGIRHSGYRFVSGFLPIDVIEIGVGSDQEVKKTLPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDI1</accession>
    <name>C7QDI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS630 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3886"/>
    <dbReference type="EnsemblBacteria" id="ACU72774">
        <property type="protein sequence ID" value="ACU72774"/>
        <property type="gene ID" value="Caci_3886"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3886"/>
    <dbReference type="eggNOG" id="COG3415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056788_4_2_11"/>
    <dbReference type="OMA" id="WHDAGTE"/>
    <dbReference type="OrthoDB" id="1435792at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025959">
        <property type="entry name" value="Winged_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13592">
        <property type="entry name" value="HTH_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_33" evidence="1">
        <location>
            <begin position="100"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18565" checksum="8A5B0A82DD5CCDA9" modified="2009-10-13" version="1">MVTRYAQGGGLDAAARARREQVRMAAAEFIAAGESDEQVARRFRVTKMSANRWRHALQTGGADALVSKGAAGHRPLLTAGQQRELMALIEAGPAAHGYLDQRWTLSRIAELIRTRFGVRFRSSGALHEMLTRIGASWQVPARRAVERDEHAIAAWRKETWPNIKARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK0</accession>
    <name>C7QDK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794353.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5766"/>
    <dbReference type="EnsemblBacteria" id="ACU74624">
        <property type="protein sequence ID" value="ACU74624"/>
        <property type="gene ID" value="Caci_5766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5766"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="ERVEFHK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="26249" checksum="46FB5217E296EF5C" modified="2009-10-13" version="1">MTEPKRDLEGKVALIIGGSRNQGAAFAENIAARGATTVITYANDDAAAEQTLVSLEKHGVTVEAIRSDARRSGDVDALFEGVVARHGKLDIVVHTPGAVMKKPLVEFTDADFDHLIDLNTRSAFNTLRAAARHIADNGRYVVLSTTLTSVMTGPYGLYSGSKAAVERMVLAAAKELGARGITVNAVAPGPIDDDFYQHAETPESMAAAANHSPRGRLGLPSDVAPVVGWLVGAEAGWVSGQTVRANGAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDQ0</accession>
    <name>C7QDQ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794403.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5816"/>
    <dbReference type="EnsemblBacteria" id="ACU74674">
        <property type="protein sequence ID" value="ACU74674"/>
        <property type="gene ID" value="Caci_5816"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5816"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_7_2_11"/>
    <dbReference type="OMA" id="RQVYFVD"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="13785" checksum="A10AC134D5843332" modified="2009-10-13" version="1">MRRTQESASEDAAVLGERAPSPRLLQDAAATFGMLAATTRLHIVWLLARAEQDVTALAEATGSNVAAVSQHLAKLKLAGLVSARREGRRQVYVVDDPHVVAIVRQMLDHHAEMAGESVPALRKSAAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDY2</accession>
    <name>C7QDY2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RibD_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7746"/>
    <dbReference type="EnsemblBacteria" id="ACU76570">
        <property type="protein sequence ID" value="ACU76570"/>
        <property type="gene ID" value="Caci_7746"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7746"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_1_11"/>
    <dbReference type="OMA" id="QGNRVLH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="20767" checksum="F610C1C6EA73A363" modified="2009-10-13" version="1">MADAVSLDGFFATEDDQVDPLHDFYFKGDTPIDAGNRHTSFRASAASAKYLAQEWSQIGAMVIGRRLFDITNGWDGVPVAGDRVFVVTHSVPTDWEFIDTAPYTFVTDGVASAIAQAKEVAGPDRVVSLNGGDVGGQAFEAGLVDELDVALVPVVFGSGKRFFGGFTGKVLLDDPTAVVQGDRVTHLHYKVRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE22</accession>
    <name>C7QE22_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="15">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_7786</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 16">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 13">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="15"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796335.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7786"/>
    <dbReference type="EnsemblBacteria" id="ACU76610">
        <property type="protein sequence ID" value="ACU76610"/>
        <property type="gene ID" value="Caci_7786"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7786"/>
    <dbReference type="eggNOG" id="COG0115">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_2_11"/>
    <dbReference type="OMA" id="LTEVFAC"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="PTHR11825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 15 17" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15 17" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU76610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="39112" checksum="4042149D9B439CBB" modified="2009-10-13" version="1">MTLTIDLKPSSTPKAVEEREALKAVGGFGQIFSDHMVTIRYTEGKGWHDAVLEAYGPVSLDPAASVLHYGQEIFEGLKAFRTADGQIVSFRPDANAARFNRSAARMAMPELPEDLFLAAIDALVTVDREWVPEGEGRSLYLRPFMFATQVGLGVNSPSKEYLFMLIAGPAGSYFAGGVKPVTVWLSEDYVRAVKGGTGEAKCGGNYAASFLAQAQAVEQGCDQVVWLDGVDHKYVEEMGSNNLYFVYGTGAEARLMTPALTGSLLPGITRDSLLKVAADLGIPAEEGTISVEQWRDGVAAGEITEVFGCGTAAVVTPLGRVKGKDGEFAIGDGEPGPVTLRIREALLDIQTGKAPDLHHWLRKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE95</accession>
    <name>C7QE95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Auxin Efflux Carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786080.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1866"/>
    <dbReference type="EnsemblBacteria" id="ACU70786">
        <property type="protein sequence ID" value="ACU70786"/>
        <property type="gene ID" value="Caci_1866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1866"/>
    <dbReference type="eggNOG" id="COG0679">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056175_2_2_11"/>
    <dbReference type="OMA" id="TTFFWTL"/>
    <dbReference type="OrthoDB" id="2033473at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="35896" checksum="00435092FD97C3C4" modified="2009-10-13" version="1">MLSAFIPIWLLTGLGYLAARFNLVGAVSADVEAVLGRFVFRVAMPASLFGMLARSDLHALANTSIVAFGVSSLAACGLGLVISTRVFGRDVSNGAVVAMASGYVNSANLGIPVAIQVLGNAAFLSTVILFNTVLVTPILMTLMGLGDGPSPGIRHRLRGIALLPVHNPIIIASAFGALVSGTHFHVPADVSSALTLLGGAAVPVALITLGMSLYGGSGKGTAKDGSRDASRHTSNDAYTSAENSSIASENLNPEQRIEKSRIAEAAIALTLKIALQPVLAYLLARYALDLSGRDVLAVTLCAALPTAQNVFIYASEYALDTVFARNAVIFSTVTSMAGLWTVVALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA5</accession>
    <name>C7QEA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5-oxoprolinase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">3.5.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786090.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1876"/>
    <dbReference type="EnsemblBacteria" id="ACU70796">
        <property type="protein sequence ID" value="ACU70796"/>
        <property type="gene ID" value="Caci_1876"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1876"/>
    <dbReference type="eggNOG" id="COG0145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002157_1_2_11"/>
    <dbReference type="OMA" id="HAMTVSV"/>
    <dbReference type="OrthoDB" id="327092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="204"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="690" mass="72988" checksum="9E45D43B92956CEF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEB1</accession>
    <name>C7QEB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786096.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1882"/>
    <dbReference type="EnsemblBacteria" id="ACU70802">
        <property type="protein sequence ID" value="ACU70802"/>
        <property type="gene ID" value="Caci_1882"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1882"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102484_4_1_11"/>
    <dbReference type="OMA" id="PALMVPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012551">
        <property type="entry name" value="DUF1707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08044">
        <property type="entry name" value="DUF1707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20055" checksum="400DCBB5671B12B7" modified="2009-10-13" version="1">MRVSDSERQEVVEVLKQALDDGRLKMDEYVERMEKAYEAVTIGDLELLHDDLPRGGAHTPPAPAAPYYAPAPIPTPPAPAPAPQPHPVYLVPTPPPAPPPTPHPGISGAYVDLPGGLKVLWTILSAAVAINVVVWVLLGLTTASFPYPWPLWVAGPAGAALFGISAPVVQARRARWEKQRRQLPPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI7</accession>
    <name>C7QEI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1958"/>
    <dbReference type="EnsemblBacteria" id="ACU70878">
        <property type="protein sequence ID" value="ACU70878"/>
        <property type="gene ID" value="Caci_1958"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1958"/>
    <dbReference type="HOGENOM" id="CLU_108887_0_0_11"/>
    <dbReference type="OMA" id="WPIVARE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="17302" checksum="1AFC40A8D2289485" modified="2009-10-13" version="1">MKARRIEVTDAIRASDELPELPVPDYASAFAVPIPQTATRSPEDWARSVFEDAPSPIRRLVRTGWRFPLRFDLAAPGPDQVLGARITSSAASRIILEQRSPALLAHNIVSVEPARVVWVTVVSYRRPIGRPLWALSALIHHRVLPYLLTRAARTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEM9</accession>
    <name>C7QEM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbon monoxide dehydrogenase subunit G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792528.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3913"/>
    <dbReference type="EnsemblBacteria" id="ACU72799">
        <property type="protein sequence ID" value="ACU72799"/>
        <property type="gene ID" value="Caci_3913"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3913"/>
    <dbReference type="eggNOG" id="COG3427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097461_0_0_11"/>
    <dbReference type="OMA" id="AHANFRI"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010419">
        <property type="entry name" value="CO_DH_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38588">
        <property type="entry name" value="PTHR38588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06240">
        <property type="entry name" value="COXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="23218" checksum="D0BF34ADDF2B366A" modified="2009-10-13" version="1" precursor="true">MIIIKEEIAVPSPRARVWEVVSNPEDVVSCISGAELGAAHDDGSFDGALTIKFGAIRVKFAARVRVELDEAEHTGRLSARGGDGQGATRFQAEAEFRVVEGDGAGETGVGSRSARVAMTGTVTLTGKLASLVEAGAGAVVSRMTKDFTAKLVWKCTETELAPSLASALTLVEPAEVRVGLPSRIRAWFARVVLRRPPALAIATVQNTVQNEEIGSGHGPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QES9</accession>
    <name>C7QES9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3973</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3973"/>
    <dbReference type="EnsemblBacteria" id="ACU72849">
        <property type="protein sequence ID" value="ACU72849"/>
        <property type="gene ID" value="Caci_3973"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3973"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023176_0_0_11"/>
    <dbReference type="OMA" id="MLRGPYE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983154" evidence="9">
        <location>
            <begin position="26"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="10">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="11">
        <location>
            <begin position="334"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU72849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="565" mass="58356" checksum="F90D659F0C171E74" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET4</accession>
    <name>C7QET4_CATAD</name>
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        <submittedName>
            <fullName evidence="4">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3978</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3978"/>
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        <property type="protein sequence ID" value="ACU72854"/>
        <property type="gene ID" value="Caci_3978"/>
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    <dbReference type="OMA" id="GPAIFLN"/>
    <dbReference type="OrthoDB" id="1771853at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sortase"/>
    </dbReference>
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        <property type="entry name" value="Sortase_dom-sf"/>
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        <property type="entry name" value="Sortase_F"/>
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        <property type="entry name" value="TAT_signal"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
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            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="25030" checksum="33924C9872F9B5C5" modified="2009-10-13" version="1" precursor="true">MSWLTRLFGSGRRRLLASAAAVLLLASAGGLALGFAAQHHPPQPPASAALPAAGVPNAASAGTTPSTSPAPASPSPAATPATPAAPTKPAAPATPTAAPTAISIPEIGVHHTLIQLGQNSDGTIQTPPLTDPSIPGWYRYSPAPGQVGPSVIVGHIDGTTGAKGVFYNLGALRPGDTVDVSRSDDTVAVFRIDGINKYAKSAFPTATVYGNTTNPQLRLITCAGPFQNQHYLDDIVVYASLTAIHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF01</accession>
    <name>C7QF01_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794488.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5901"/>
    <dbReference type="EnsemblBacteria" id="ACU74759">
        <property type="protein sequence ID" value="ACU74759"/>
        <property type="gene ID" value="Caci_5901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5901"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="WFKRERN"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="30134" checksum="C3E8056D47784E8E" modified="2009-10-13" version="1">MEIRELQYFVAVAEELHFGKAAERLDIAQPALSRTIAQLERRLGVTLLERTSRKVALTDAGSVLLAEARSILSAVATAERRTQEAATSQPRVVLAVKTGTAGELLAKLLDAYRAEPGAAPVELLLCEAHQHRRLLLSGQADVALLHLPFDPAEGLDTETLYTEKQVAILPIAHPLAARAQIRAAELAALPDLPPARWCRADGSYPDGPGPEVRNLGQIYQLIALGRTTVVVPESAAVDLRRDLVTVPVLDAPPVTTVIAWPPHSRQRAVADLVRVATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF76</accession>
    <name>C7QF76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cholesterol esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794563.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5976"/>
    <dbReference type="EnsemblBacteria" id="ACU74834">
        <property type="protein sequence ID" value="ACU74834"/>
        <property type="gene ID" value="Caci_5976"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5976"/>
    <dbReference type="eggNOG" id="ENOG5030F4R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092426_0_0_11"/>
    <dbReference type="OMA" id="CQSVDLG"/>
    <dbReference type="OrthoDB" id="1665716at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046198">
        <property type="entry name" value="DUF6230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19741">
        <property type="entry name" value="DUF6230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21156" checksum="9D4D4C5187E43131" modified="2009-10-13" version="1" precursor="true">MATKPKAEGKVRYRRAAIPGMAALAATGALVVLTAQGALGVQFAISGMPFVVTADHLTGTNFQQFGDLDSGLSGNPWLKSSNGQAVVMTSVIGDAKVYNLCQSVNLVGVNLVIRAGTGATPVHATNLVLDSTDLTGDATFNNIQIGRDASDLTQVPSIKGHAYTFSQQADSVDIKNVRQDNYASTASTFSLPNLSMSFQSKGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFB7</accession>
    <name>C7QFB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76694">
        <property type="protein sequence ID" value="ACU76694"/>
        <property type="gene ID" value="Caci_7871"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7871"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_33_0_11"/>
    <dbReference type="OMA" id="ESAPREY"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="23071" checksum="ADB3348D7FD5C0EF" modified="2009-10-13" version="1">MAAENGRRRREYAPRVPIEQRRSDVLDAALRIVVREGHAAVTMEAVAAAAGVTKPVVYGVFPNREALLGDLLRREQAAALEQLVELLPTLRKGLNAGAHPADVLADALDGFLAAVRNAPERWSCIVVPMADMPAQFNAAREETRALVLASAEELGRWITRTFDAPPDLDPELIAHTVVTLAEMAARLVLTDPEKYEPARFVKGLRAAVGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG21</accession>
    <name>C7QG21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70998">
        <property type="protein sequence ID" value="ACU70998"/>
        <property type="gene ID" value="Caci_2079"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2079"/>
    <dbReference type="HOGENOM" id="CLU_2218327_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="106" mass="10389" checksum="233FC501E8EDE174" modified="2009-10-13" version="1">MLTAGMRPVGGLGAAACFRTRDHAARLVVRRGAAVGSGGDATAGPGDVAEVLLNHAIADTEQVSAAVAQSLAAGPGDVAEALLNHAIADAEPVSAAVARSLKSPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG95</accession>
    <name>C7QG95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4075"/>
    <dbReference type="EnsemblBacteria" id="ACU72940">
        <property type="protein sequence ID" value="ACU72940"/>
        <property type="gene ID" value="Caci_4075"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4075"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057331_0_0_11"/>
    <dbReference type="OMA" id="YVFQYGP"/>
    <dbReference type="OrthoDB" id="685012at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="2">
        <location>
            <begin position="207"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="434" mass="45004" checksum="0A7D50E20A8B9769" modified="2009-10-13" version="1">MSTPTLAPPGIADTAPDFEEHPAAPASEEDSAPPASEEDSAASAPEADPDSDSETDPESLTASGHTRPGYLRMQVARVLADTPGAEMSVGDVARILGNSGGAIGNALNKLVELEQAVQVGKAPRRWQANAETEKAAGTATIARGTGPATPAPGGTTAPPLPKAAKAAPSRPEPITRPNGQQYHPRALGKHTDVTALRALREAGVPALLYGPPGTGKTSVIEAAFDDLITIAGDGDTTVGDFIGEYTQAEDGTYQFVYGPLVIAMQEGRPLLIDDATLISPKVLAAAYPAMDGRKQIIVKAHKGETITAAPGFYVIAGHNPGVAGAVLTEALSSRFGVQIQVGSDYDLALFLKVEPKAVQIAKNLAERQTKGLAGWAPQLRELKAFQEVYTLLGADIAYANLLGVAPEEDRALVADVIARVLGRKVTALALGKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA0</accession>
    <name>C7QGA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV secretory pathway VirB4 protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4080"/>
    <dbReference type="EnsemblBacteria" id="ACU72945">
        <property type="protein sequence ID" value="ACU72945"/>
        <property type="gene ID" value="Caci_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4080"/>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009097_4_1_11"/>
    <dbReference type="OMA" id="KRRFMRD"/>
    <dbReference type="OrthoDB" id="182908at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P-loop_TraG" evidence="2">
        <location>
            <begin position="250"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="2">
        <location>
            <begin position="443"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="631" mass="67912" checksum="BE8F1915BA127783" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGD6</accession>
    <name>C7QGD6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_4117</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4117"/>
    <dbReference type="EnsemblBacteria" id="ACU72981">
        <property type="protein sequence ID" value="ACU72981"/>
        <property type="gene ID" value="Caci_4117"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4117"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_3_0_11"/>
    <dbReference type="OMA" id="HGFRVLH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="114"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="206"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="298"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="390"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="482"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="574"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="666"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="971"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="1469"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="906"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="1519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU72981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1588" mass="168029" checksum="B3C0785F75A66443" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGN4</accession>
    <name>C7QGN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6057</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794643.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6057"/>
    <dbReference type="EnsemblBacteria" id="ACU74914">
        <property type="protein sequence ID" value="ACU74914"/>
        <property type="gene ID" value="Caci_6057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6057"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="HPMWRDG"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="23206" checksum="5C1FDDCAF92CB0C8" modified="2009-10-13" version="1">MVADDHPMWRDAVARDLAEAGYDVVATAGDGEEAVRRGTAARPQVVVLDMQMPRLSGAEVTARLVAADPDVKVLVLSASGEQQDVLQAVKAGAIGYLVKSASREELLAAVERIAVGDPVFTPGLAGLVLGEFRKLAMVPPGAGAGTAADTPRLTDRETEVLRLVAKGLSYKQIADRLVLSHRTVQNHVQNTLNKLQLHNRVELVRYAIAQGLDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGN6</accession>
    <name>C7QGN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6059"/>
    <dbReference type="EnsemblBacteria" id="ACU74916">
        <property type="protein sequence ID" value="ACU74916"/>
        <property type="gene ID" value="Caci_6059"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6059"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_4_0_11"/>
    <dbReference type="OMA" id="RPWVEGL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="3">
        <location>
            <begin position="50"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="31677" checksum="A53F98E7F53AA6C7" modified="2009-10-13" version="1">MKSLYAYTALRRGRRLFYGLLKVIFLGPLLRVLFRPWAKGLEHIPAEGPVILASNHLSFSDSFFMPLMVPRPVYFLAKSDYFTGKGIKGRLTAAFFRGVRSVPIDRSSGKAADPALKTALRILSEGKALGLYPEGTRSPDGRLYKGRTGIARIALESGIPVVPCAMVGTYEIQPTGQVMPKIKRVGVRFGEPLDFSRYREVPGAVDDRYILRSITDEIMYALMDLSGQEYADIYATDAKKIIAAEKAADRAEQRAEAKKAAVEERRAAIEEQRQQEADEDARRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH57</accession>
    <name>C7QH57_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemL</name>
        <name evidence="9" type="ordered locus">Caci_8084</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796632.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8084"/>
    <dbReference type="EnsemblBacteria" id="ACU76907">
        <property type="protein sequence ID" value="ACU76907"/>
        <property type="gene ID" value="Caci_8084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8084"/>
    <dbReference type="eggNOG" id="COG0001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_5_11"/>
    <dbReference type="OMA" id="WGPLIFG"/>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="439" mass="45548" checksum="CD00CB40B8E6F4C2" modified="2009-10-13" version="1">MNAHPYEPPETQSQHLFDRARAVTPGGVNSPVRAFGAVGGTPRFIASGEGAYLTDVDGNRYVDMVCSWGPLILGHNHPAVLEAALKALQSGTSYGAPSAGEVELAEEMVARIAPLQQVRLVSSGTEATMSAIRLARGFTGRTKIVKFAGCYHGHVDSLLAAAGSGVATFALPDTPGVTGAQAGDTIVLPYNDVEAVQAAFQTHGAEIACLITEAAPGNMGIVPPQPGFNQFLADVCRAHGALFISDEVMTGFRASREGVYGIDGVVPDLMTFGKVMGGGFPAAAFGGRADVMGHLAPVGPVYQAGTLSGNPVATAAGLATLRHCTPDVYSHLDTTAHEIADLASEALAKEGVPHTVQFAGTMFSVFFTGDPVANYEDAKKQDTKAYAEFFHAMLNHGVYLPPSSFEAWFVSAAHDAAALETIAEALPHAARAAAAAEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH73</accession>
    <name>C7QH73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784307.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0057"/>
    <dbReference type="EnsemblBacteria" id="ACU69012">
        <property type="protein sequence ID" value="ACU69012"/>
        <property type="gene ID" value="Caci_0057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0057"/>
    <dbReference type="eggNOG" id="COG0746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055597_1_0_11"/>
    <dbReference type="OMA" id="FDCDTWD"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045598">
        <property type="entry name" value="DUF6457"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20058">
        <property type="entry name" value="DUF6457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="2">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6457" evidence="3">
        <location>
            <begin position="206"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="34997" checksum="3B27E008EE5D7F35" modified="2009-10-13" version="1">MDRLSGPGEPFDVIVLAGGGARRLGGTDKPALEIGGVSLLDRVLAACEGAASVAVVGPPRPVARQVVFTREFPPGGGPVPALAAGMTVGSAELVAVFAADMPLLDEEAVTVLRRSLTADAVFFTDERGKDQPLAAIYRRNTLAAALDALPELRGARLFSVVEGLDATRIPDTRGVTADCDTWEAVHAARALIATRPAAKAKMGDMDDKKLLADWCAAAAAELGLTGHELAESDLDAILGLAGVAAHNVLRPAAPLTTFLAGYAVGLRSSAGGGRGALDGPIAKLSALAQAWDPAADGPAGTGHGGAASGTVGGSVAASPTAVRDATTGAAASAKSSSGTSGDRAADAAGSGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI20</accession>
    <name>C7QI20_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4201"/>
    <dbReference type="EnsemblBacteria" id="ACU73065">
        <property type="protein sequence ID" value="ACU73065"/>
        <property type="gene ID" value="Caci_4201"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4201"/>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_1_0_11"/>
    <dbReference type="OMA" id="FRDRERW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022291">
        <property type="entry name" value="Bacteriocin_synth_cyclodeHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027624">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03882">
        <property type="entry name" value="cyclo_dehyd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03604">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="264"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="647" mass="70477" checksum="ACE9ED41B5C60760" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI90</accession>
    <name>C7QI90_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_34 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4271"/>
    <dbReference type="EnsemblBacteria" id="ACU73135">
        <property type="protein sequence ID" value="ACU73135"/>
        <property type="gene ID" value="Caci_4271"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4271"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142189_0_0_11"/>
    <dbReference type="OMA" id="LRLAIMS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027395">
        <property type="entry name" value="WH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13601">
        <property type="entry name" value="HTH_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_34" evidence="1">
        <location>
            <begin position="25"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="114" mass="12035" checksum="CE7DADDF782F88FD" modified="2009-10-13" version="1">MTTKSGAPDPDVLEPDEAFGTLPKLKLAAFLAGCAEAEFGTVAETCAIAGPTLSKAATALEEAGYVRIRKGHVGRRPRTWLSLTAEGRTAFDRHLAALARLTEAGRAQAENVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIA1</accession>
    <name>C7QIA1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794707.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6124"/>
    <dbReference type="EnsemblBacteria" id="ACU74978">
        <property type="protein sequence ID" value="ACU74978"/>
        <property type="gene ID" value="Caci_6124"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6124"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124277_3_0_11"/>
    <dbReference type="OMA" id="YEVHGTI"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15915" checksum="0DF8DB303167E318" modified="2009-10-13" version="1">MSEHVRTSRETVELLLRTVVEGSRDELADLYAEDVVITNPFIAEEHSAYRETRGNAALRARTKPFAQFLQYSQVKDVTLHETTDPQVTVVEFTVVGTLLPTGEGFEMPYVNVIRVVDGLIAESRDYGDSVRAAKLLESIQSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV0</accession>
    <name>C7QIV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796725.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77000">
        <property type="protein sequence ID" value="ACU77000"/>
        <property type="gene ID" value="Caci_8177"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8177"/>
    <dbReference type="eggNOG" id="ENOG5033QF0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_466027_0_0_11"/>
    <dbReference type="OrthoDB" id="492305at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="569" mass="61516" checksum="88F28AF00B2A7562" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV3</accession>
    <name>C7QIV3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796728.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8180"/>
    <dbReference type="EnsemblBacteria" id="ACU77003">
        <property type="protein sequence ID" value="ACU77003"/>
        <property type="gene ID" value="Caci_8180"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8180"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044049_0_0_11"/>
    <dbReference type="OMA" id="YWGLFFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981688" evidence="3">
        <location>
            <begin position="17"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="49219" checksum="122DFB434528ABD8" modified="2009-10-13" version="1" precursor="true">MTLTAIRRLAKSPSAMMTASVLLVAVGGYLFLLLAGGLEDKTAAAAMVSMYVLVNLIGQGVFAGLEQETSRSLSQAAAVGGDLAPVMRRAVRHTAALLAVCCLFVVAASPILVAGPLHKQWALIPTVLIGTVSYSVSYLVRGLLGGQQLFGGYAAALVAEGMSRIVPLIAIAALGAGSGFLYCLVYACGLFLSAGVGWFFWLRPRFAQQRAQAADGVRAPAHQAPAEEPSTDDHEKGLRSWLSAGLLFLVGAALLTQLVANLPALGASSRLGAHPATATAFVQAATLSRIPLLLVGPVTALLLPRLTAAGTTGDLRTVRTTVRTGSFAMLGLGALAAAGIGVLGPWALKTYFNATGISALSLALMAIGTAGLMTVGVLQPTLIGLGRQRQVPIAWAIGSVAMVVAVVWPGDAVSAAVAASLVGPAGVVLVMAFSLRGLRGERFEGAEGESADSDAPNAVSATTPAVTPTAAPAGAPSAEAQAASRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJN6</accession>
    <name>C7QJN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786552.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2341"/>
    <dbReference type="EnsemblBacteria" id="ACU71259">
        <property type="protein sequence ID" value="ACU71259"/>
        <property type="gene ID" value="Caci_2341"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2341"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_2_11"/>
    <dbReference type="OMA" id="QNHMYNA"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="24097" checksum="5A09AFE26CDAD0CF" modified="2009-10-13" version="1">MSLRSIQPSPLVEQAAEQLREQITGGAWPVGTKLPGETTLAASLGVGRSTVREAIRALAGEGLLQPRQGAGVFVLATESRTDLADHLRKASLADLYEVRMMIETRAARLAAERRTPADAAALEAALERRTRAARRSDEEFIEADIALHTAVVAAAGNPVLTALFEQFVPTLRETLTALVRSSGRADENLGHRAHAALVAAVAEGNPDRAETVVAEEIASTTLRRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKC1</accession>
    <name>C7QKC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794924.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75195">
        <property type="protein sequence ID" value="ACU75195"/>
        <property type="gene ID" value="Caci_6341"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6341"/>
    <dbReference type="HOGENOM" id="CLU_2951810_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="59" mass="6720" checksum="91CFE473314DEB37" modified="2009-10-13" version="1">METAAFIFILVLLVAPIVYGLERNERRQNGPRPQLNGSAGGQDRDLERTWHDISVSRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKC6</accession>
    <name>C7QKC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794929.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75200">
        <property type="protein sequence ID" value="ACU75200"/>
        <property type="gene ID" value="Caci_6346"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6346"/>
    <dbReference type="HOGENOM" id="CLU_155188_1_0_11"/>
    <dbReference type="OMA" id="KSPMGDQ"/>
    <dbReference type="OrthoDB" id="1852398at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11516" checksum="64D645C8D4361F2B" modified="2009-10-13" version="1">MSAAGTWNLTIDSPLGKQRASVTLTQSADNTWTGNSLDLVSGEASACYNIEVNGEEVGWQQQITKPMKLKLTYKLKLDGDTLAGKVKAGLFPASKVVGERVSEDAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKP5</accession>
    <name>C7QKP5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8321"/>
    <dbReference type="EnsemblBacteria" id="ACU77144">
        <property type="protein sequence ID" value="ACU77144"/>
        <property type="gene ID" value="Caci_8321"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8321"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_8_1_11"/>
    <dbReference type="OMA" id="CKWQLSF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981082" evidence="2">
        <location>
            <begin position="23"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="113"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="643" mass="68684" checksum="AEF6A1909871375E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKP9</accession>
    <name>C7QKP9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <shortName evidence="6">PBG</shortName>
            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemC</name>
        <name evidence="9" type="ordered locus">Caci_8325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="6">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796873.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8325"/>
    <dbReference type="EnsemblBacteria" id="ACU77148">
        <property type="protein sequence ID" value="ACU77148"/>
        <property type="gene ID" value="Caci_8325"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8325"/>
    <dbReference type="eggNOG" id="COG0181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019704_1_0_11"/>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="1450400at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="19"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="8">
        <location>
            <begin position="236"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="32120" checksum="037E39D4825D57A5" modified="2009-10-13" version="1">MSGSPADEGSPAPGPERALRLGTRASTLALAQSGMVAEALTAATGRAVELVHVTTYGDTSREALSVIGGTGVFVNALREAIYAGDVDFAVHSLKDLPTAAPEGLHLAAITERAAVNDALVARDGLKLADLPAGAKVGTGAARRMALLKMIRPDLEIVPIRGNVDTRVNHVRSGDLDAVVVALAGLQRLGRAEEATEVFGPDVILPSPGQGALAVECKDPELAELLAVLDSPLTRAAVVAERTMLAVLEAGCSAPVGGHAIALDDNVLSLTGVVATVSGSRGLRLSHAGAVSEPEALGRRVAQALLADGAAELMEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVC2</accession>
    <name>C7PVC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784573.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0325"/>
    <dbReference type="ESTHER" id="catad-c7pvc2">
        <property type="family name" value="Bacterial_Est97"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69278">
        <property type="protein sequence ID" value="ACU69278"/>
        <property type="gene ID" value="Caci_0325"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0325"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097569_0_0_11"/>
    <dbReference type="OMA" id="PVGYWGV"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27468" checksum="253ADC43CEDCB6DD" modified="2009-10-13" version="1">MSTSLLFTSDSSADGVRERDFTVGGVPGVLWSPDSRPDRAPLVLIGHGGGIHKKAPGSAGRARALVLGCGFHVAAIDAPGHGDRPRTEHDEREIDALFAARDAGEPEGPIVVRYNAYLAEQAVPEWRATLDALQELREIGADGPVGYWGINMGTAIGIPFVAADPRITAAVFGQHWPDFLAEPAKRITIPVEFDLQWDDEHIPRSAGLALFDAFASPEKTLHANAGRHKQLPRFEADSAVRFFARHFGAPAAGTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVY2</accession>
    <name>C7PVY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromosome segregation and condensation protein, ScpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2456"/>
    <dbReference type="EnsemblBacteria" id="ACU71374">
        <property type="protein sequence ID" value="ACU71374"/>
        <property type="gene ID" value="Caci_2456"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2456"/>
    <dbReference type="eggNOG" id="COG1386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045647_5_1_11"/>
    <dbReference type="OMA" id="TKPEYHD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="33868" checksum="849A622B59C7820A" modified="2009-10-13" version="1">MSDDWEYDSPEYAAHAEAAEAAENAAEDHAAEQAGSAPAAEVPAASAEAPGASSQTADSADATPAAESTEREPAASPAPASSLPAPRSKSKSRLPSPRTESTPGDSTPGNSTPGDSTPADPALAHLDDATWQLSTDMAPLPPLRQCLEAILLVVEEPVVDVVLAQITERPRDEVVQTLHELAAEYTEQQRGFDLRQVAGGWRFYTRTACAPLVEKFVLDGQQAKLSQPALETLAVVAYRQPVSRSRISAVRGVNCDGVMRTLLTRGLIEEAGTDADSGAILYRTTLLFLEKMGMHTLDELPALAPLLPSVESMEESETLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW35</accession>
    <name>C7PW35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793012.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4419"/>
    <dbReference type="EnsemblBacteria" id="ACU73283">
        <property type="protein sequence ID" value="ACU73283"/>
        <property type="gene ID" value="Caci_4419"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4419"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_0_11"/>
    <dbReference type="OMA" id="PWDSGPV"/>
    <dbReference type="OrthoDB" id="534010at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981315" evidence="4">
        <location>
            <begin position="30"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="456" mass="47722" checksum="9658DCE3D35DCEBD" modified="2009-10-13" version="1" precursor="true">MTISRRRGVLLGATALAVALAATACSSSASSGGSGKTSSGSSQAATVTDADLQAALTAGGNLTVWAWEPTLKKVVADFQTKYPNVHVNLVNAGTGNDEYKALQNAVQAGKGVPDVAHIEYYALPQFELTKSVANLDEFGAAALNGTFTPGPWSSVQAAGGVYGLPMDSGPMALFYNQTVFTKFGITTPPATWDEYIADAKKIHTADPSVYMTNDTGDAGFTTSMIWQAGGKPYSVSGTTLGVNFAGDAGTQKFATAWQQLLDGHDLAPISSWSDAWYQGMASGKIASLTIGAWMPASLESGVKSGSGQWRVAPMPQWTAGGKVTSENGGSSLAVMKASTNQKLAYAFLKYATVDEGAQTRVDNGAFPATVKQLNSPDFLNKTDAYFGDQKINQVLAQSAAEVAPGWSYLPFQVYANSVFNDTAGKAYIGSSSLADGLKAWQDASIKYAKDQGFTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWI0</accession>
    <name>C7PWI0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ordered locus">Caci_6406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794989.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6406"/>
    <dbReference type="EnsemblBacteria" id="ACU75260">
        <property type="protein sequence ID" value="ACU75260"/>
        <property type="gene ID" value="Caci_6406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6406"/>
    <dbReference type="eggNOG" id="COG0225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_2_11"/>
    <dbReference type="OMA" id="GYCAFVV"/>
    <dbReference type="OrthoDB" id="1554384at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="6"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="19246" checksum="0B237A6113ADD0A5" modified="2009-10-13" version="1">MATERAILAGGCFWGMEELLRREPGVVSTRVGYSGGDTPNATYRNHGDHAESIEIGYDPEVTDYRALLEFFFQIHDPTTRDRQGEDRGRSYRSAIFYLNDEQKRVAEDTIADVEASGLWPGKVVTEVTPAGDFWEAEPEHQDYLQRYPNGYTCHYPRPNWKLPRRAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT9</accession>
    <name>C7PWT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lsr2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796921.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8373"/>
    <dbReference type="EnsemblBacteria" id="ACU77196">
        <property type="protein sequence ID" value="ACU77196"/>
        <property type="gene ID" value="Caci_8373"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8373"/>
    <dbReference type="eggNOG" id="ENOG5032RKK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139818_0_0_11"/>
    <dbReference type="OMA" id="RIPKHVY"/>
    <dbReference type="OrthoDB" id="370464at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024412">
        <property type="entry name" value="Lsr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042261">
        <property type="entry name" value="Lsr2_dimerization"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11774">
        <property type="entry name" value="Lsr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="12507" checksum="6B5CA666CA3C7CB0" modified="2009-10-13" version="1">MAKRTIEVFHDDLDGSEGASTVKFGLDGKSYEIDLSESHEKELRKALEKYVGAATQVTAQSASASGRRKYGTGPARRDTKHIREWLRNVEGVEISDRGRIPTDLMNRYNAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW3</accession>
    <name>C7PWW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8397</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8397"/>
    <dbReference type="EnsemblBacteria" id="ACU77220">
        <property type="protein sequence ID" value="ACU77220"/>
        <property type="gene ID" value="Caci_8397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8397"/>
    <dbReference type="eggNOG" id="COG1813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032305_1_0_11"/>
    <dbReference type="OMA" id="WEDKCEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="30"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="46229" checksum="3B3004EE85EF890D" modified="2009-10-13" version="1">MSCGLGTGTGRRSGTGGNRVVSGPEDFAALLGDLKERSGLSYGVLAKRLHVGTSTLHRYVQGETVPPEYGVIEKFARLTGASATEMATLYRLWMAAGEARSSTVAEAVSVVPPAPPAPPVSPVEDSSGDSSIATTPSPVSRRRRRLLPALAVLAVVGVGAAVAGVAFASSPGSNSDRTAASTVSSSTSSPLQSSSSLQSPPSASAPSSSSTGAATGSSASSAPSNSSSSTSPSTSPSTSSAPPIAVTIRPYQWEDKCEQWYLLNKKPGEVPPPPTEADARGWASALGAVSAGTMKIELSVQGTSSSTVVLQGLHVRTVSKAAPLPWSAYSMASGCGGGLMPVSFSINLDADRPLASPKAGQQGDNVVRAEDFPFEVSESDPQVLTVYAHAHTVNAAWYLELDWSSGSRTGTVRIDDHGKPFQTSGAQGRPIYDYDTSSNDWEPDTTAVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX32</accession>
    <name>C7PX32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8466</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8466"/>
    <dbReference type="EnsemblBacteria" id="ACU77289">
        <property type="protein sequence ID" value="ACU77289"/>
        <property type="gene ID" value="Caci_8466"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8466"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="ALVIPQY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="110"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="34837" checksum="3B026223FF130D73" modified="2009-10-13" version="1">MTQQTFTRGLMGRNRFQGRRPKKGADTYQRTLISRTQLNTARGKRFYWTALTIALVLASLVFIGPLFWMATGGFKTSQELVRNPPVLLPSHPSTHAFTLAWDRLGMAQLLWNTIVYAGGALLFQLIFCVSAAYSLSKLRPIFGNWILALMLASMMIPAAALVIPQYLTVLDLPLVHWNLQNTPWVIWLPTVANAFNVFLLKRFFDSIPNDLLDAASVDGAGPLRTLWRIVLPMSRPILGVVSIFAVVAVWKDFLWPLITVPAHETLNVGVNTAATSMPDNALVGGLFLASIPTIVLFLFFQRNIMAGLTVGGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX55</accession>
    <name>C7PX55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784701.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0454"/>
    <dbReference type="EnsemblBacteria" id="ACU69406">
        <property type="protein sequence ID" value="ACU69406"/>
        <property type="gene ID" value="Caci_0454"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0454"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_336414_0_0_11"/>
    <dbReference type="OMA" id="ENESLGC"/>
    <dbReference type="OrthoDB" id="442822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981329" evidence="3">
        <location>
            <begin position="32"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="853"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="777"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="949" mass="97367" checksum="3543D729E5A11E2B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX70</accession>
    <name>C7PX70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784716.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0469"/>
    <dbReference type="EnsemblBacteria" id="ACU69421">
        <property type="protein sequence ID" value="ACU69421"/>
        <property type="gene ID" value="Caci_0469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0469"/>
    <dbReference type="eggNOG" id="ENOG502ZH4D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1213025_0_0_11"/>
    <dbReference type="OrthoDB" id="2177966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982274" evidence="2">
        <location>
            <begin position="26"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="22273" checksum="1EA41B2373875347" modified="2009-10-13" version="1" precursor="true">MVKRKRVVAVVVAIAALGATGTASAATSGNTPAPSPTKSGAPAVAGNDTSVDKSAGKSDGKSDGKSADAGKDEFAALAAKLGVTTDRLNAAMVAAKMSLASTNGGTPQAFYAAIAANLGLPVARVQDALGTEIFRKGPEGGKPSKHGVPGPSPFTTDSAAAFVAHELGVDQKKAKTALAAVVALDDARGGVDPTSKAFGDIAASLGVSSSRLATALTDLKMSIGGTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXB7</accession>
    <name>C7PXB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0525"/>
    <dbReference type="EnsemblBacteria" id="ACU69468">
        <property type="protein sequence ID" value="ACU69468"/>
        <property type="gene ID" value="Caci_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0525"/>
    <dbReference type="HOGENOM" id="CLU_2988184_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="57" mass="5834" checksum="0E9E597B78C6CC41" modified="2009-10-13" version="1">MTSQQTYALLFDIAVILAPAHALGGLARRFGQPAVIGEISLGIPLGPTVVPAAVGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXG4</accession>
    <name>C7PXG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2499"/>
    <dbReference type="EnsemblBacteria" id="ACU71417">
        <property type="protein sequence ID" value="ACU71417"/>
        <property type="gene ID" value="Caci_2499"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2499"/>
    <dbReference type="HOGENOM" id="CLU_2002693_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="15766" checksum="C35AD684F647AD82" modified="2009-10-13" version="1">MDLSTLLLPGAQNLATAMLSDAWTATRDAVARRWGRGDHAATKQAAAELDDSRTQALALFPASAGVDAVVPAAADPALLQAFLAGYLAALARTDPGRLPALFSLTAQPGQQAAAAAARNVNYGEVERLVQVDAESIDKLVQIDGDVQGGFHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN6</accession>
    <name>C7PXN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FG-GAP repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786782.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2571"/>
    <dbReference type="EnsemblBacteria" id="ACU71489">
        <property type="protein sequence ID" value="ACU71489"/>
        <property type="gene ID" value="Caci_2571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2571"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026782_0_0_11"/>
    <dbReference type="OMA" id="VNTSDNH"/>
    <dbReference type="OrthoDB" id="1147012at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981336" evidence="3">
        <location>
            <begin position="41"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="456" mass="49076" checksum="242C0DBA07F50DD7" modified="2009-10-13" version="1" precursor="true">MNNALRAEGTRTATGRRRLAGLLATAVALITAAAMAPASAAAGTGSASSATTVQPDTGTSTAGGPISRAEIQARAQDWVNERVPYSESLHWTDSNGTYRQDCSGFISMAWHLAPDQNYGATTWSLPDFSTKLSSLDDLQPGDMIDNINTHVVMFLGWTSSSHSTAIVAEEAHSGTVAHVDSSYYTRSYLLNNGYEPFRYNKVTEYPSKMGEITDVGDQNGDGVDDFTAVERSSGFLYLYTSPGYSGTDRQKLGWGWNTMRDIAAVGDHNGDGKVDLVAVNTSDNHMYLYYGPDFSGTTRVDLGGGWSSYKDIAAVGDHNGDGIPDFVTTDSSTGNLYLYTSPNYLGSQRQQTGTGWTGTRDITDVGDHNGDGKDDFVAVNTSDNHMYLYYGPDFSGTTRVDLGGGWSGYTDIAAIGDHNGDHQPDFVTTETSTNFLYLYSSSNYLGSSRQKIGTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT2</accession>
    <name>C7PXT2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.157" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4529"/>
    <dbReference type="EnsemblBacteria" id="ACU73392">
        <property type="protein sequence ID" value="ACU73392"/>
        <property type="gene ID" value="Caci_4529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4529"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_11"/>
    <dbReference type="OMA" id="NMTEAYG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="3">
        <location>
            <begin position="185"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="30174" checksum="C8FB553D413E2DEE" modified="2009-10-13" version="1">MIERVGVVGVGQMGSGIAEVCARSGLDVIVADENAEGLKRGRDRVAVSLKRAVKAGKMSEGDAEAALGRIRFTEDLQQFADRQLAVEAVVEVEAVKTAVLSKLDLILPEDAILASNTSSIPIMRLGTATTRPNNVVGVHFFNPVPVLKLVEVIPSLATSEETKARAVAFVEQLGKQAVVAQDRAGFVVNSLLIPYLLAAIRMAEGGFASAEDIDSGMVLGCAHPMGPLALSDLIGLDTVKLAAEAMYEEFKEPLYTPPALLLRMVEAGRLGRKAGRGFYEYPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXX3</accession>
    <name>C7PXX3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4571"/>
    <dbReference type="EnsemblBacteria" id="ACU73433">
        <property type="protein sequence ID" value="ACU73433"/>
        <property type="gene ID" value="Caci_4571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4571"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_11"/>
    <dbReference type="OMA" id="MAVQATN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="21453" checksum="7EF93A5C6E735DC4" modified="2009-10-13" version="1">MTTATIKGRPRGFDRDQALEAALMEFWRHGYEATSIATLTRAMGINPPSLYAAFGDKRKLFSAAVQRYAQTHGDYGSRALDQPTARGVVETMLRLAATEYTDAHHPPGCLVIDGATNTSEASQDVAEELRAYREDTKHAIADRITADIQAGSLPPKTDAPALATFYAAVIQGMSTQARDGASEQDLQRVADVALAAWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY58</accession>
    <name>C7PY58_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795077.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6498"/>
    <dbReference type="EnsemblBacteria" id="ACU75348">
        <property type="protein sequence ID" value="ACU75348"/>
        <property type="gene ID" value="Caci_6498"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6498"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_5_0_11"/>
    <dbReference type="OMA" id="PARWKEQ"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="7">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="26752" checksum="B20F90214C5644D5" modified="2009-10-13" version="1">MTTSDGVDLPAPPWRPARGPRRPVRQRLPLSKDLIVATALRIAVAEGLDAVTVRRVGEELETGSASLYTHISGKDELFELVLDAATADVTVPAPETGRWMEQVHEVAWQIYRVLTAHNDVARVSLGVIPTGPNMLRIAEGLLDIMISGGVPVQTAAWTIDRLLLYIASDAYQSALFLAHRKPEQSIPEYAVQFLSDIREFYASLPADRFPHTSGNAETLTTGGGDERFEYGLSLLLDGLAARLPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY88</accession>
    <name>C7PY88_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6530"/>
    <dbReference type="EnsemblBacteria" id="ACU75378">
        <property type="protein sequence ID" value="ACU75378"/>
        <property type="gene ID" value="Caci_6530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6530"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="TATHEFL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="273"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="372" mass="39113" checksum="65F31049C2419738" modified="2009-10-13" version="1">MLFDSLTAVLGAGACVLIDLLVRGHPANAGVWDALLVLPLAARRARPAAAAAVLAAVCLAQWRFGSPEIGDFAVLAALYSLGAHERRRGVLLTGIAVAVLGVIMALSRWETSGNPLLVGATATGTVTAAWIAGIYTSMRRAYVESIHQRAQAAERDRDSRARIAVAQERTRLAREMHDVIAHSLSVMITLNDAAAAVEPSQLARDTIAQASDVGRQALGEMHRMLGVLRGEEDSAYEPQPGLGDLPALASLVRAAGFELELVTAGDLESLAPTAQLAIYRIVQESLTNVIKHARRVTKVLVEVSHHASLVDLRVENDGSPVAAPAATATGHGLHGMNERAALYGGEVRAAPLAAGGWCVRARLAVDHPAGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYI6</accession>
    <name>C7PYI6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797033.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8485"/>
    <dbReference type="EnsemblBacteria" id="ACU77308">
        <property type="protein sequence ID" value="ACU77308"/>
        <property type="gene ID" value="Caci_8485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8485"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1861609_0_0_11"/>
    <dbReference type="OMA" id="TRQMNEN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14575" checksum="66A3BD492ECDCCF4" modified="2009-10-13" version="1">MTAADEVPPGHPRLAFDRAKLAELVADSERRMAVIADAQRRVSELSVSVRSRDRSLTVGLGAGGALTELTFHTGAYRDMAPAELSRLLLDTIAAARGVYAAEVADAMAPVREGAVLPFEDIMAGKFDISEFLRGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYI7</accession>
    <name>C7PYI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797034.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8486"/>
    <dbReference type="EnsemblBacteria" id="ACU77309">
        <property type="protein sequence ID" value="ACU77309"/>
        <property type="gene ID" value="Caci_8486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8486"/>
    <dbReference type="HOGENOM" id="CLU_1944848_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="13447" checksum="D07FB0E521DB0E79" modified="2009-10-13" version="1">MTSIQADPDDLDKHGRAFDGHVADMSSVHDEMYALLAGDIGIGNDDFSRGFRENYVTQVRNLADSVKGARDGVRGISQGMIRMAADYRATDDASLKGVSSLGSSLGLPPGGGPAGGPHTTPHPTPHSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYY0</accession>
    <name>C7PYY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784831.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0599"/>
    <dbReference type="EnsemblBacteria" id="ACU69536">
        <property type="protein sequence ID" value="ACU69536"/>
        <property type="gene ID" value="Caci_0599"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0599"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065561_0_0_11"/>
    <dbReference type="OMA" id="GLRGWFL"/>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="2">
        <location>
            <begin position="96"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="381" mass="40994" checksum="24B2AE3D8E31D332" modified="2009-10-13" version="1">MTAKHTAGTAAAQYSPGADPGGKRVQRPAAEVRYAAELAQLAADDQGERPPGWALSLRAARRFILGDEQAGISRKFVGDPSLIDRALVSLATSRGLMLVGEPGTAKSLLSELLAAAVSGDSTLTVQGGAATTEDQIKYSWNYALLVADGPSTKSLVPAPLYRGMTEGRVVRFEEITRCPLEVQDCLLSPLSDRVMAVPELTGEDALVFAREGFNIIATANTRDRGVNEMSAALKRRFNFETVFAISDFATELALVEQEATHLLQGSGVTVPPRRDVLEVLVTAFRELRGGKTERGDAMERLSSVMSTAEAVSVAHAVGLRGWFLRGDAGSASDIVECLAGTAAKDNNDDLAKLRTYLEQHAQRRKGDQWQELYDARHRLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI0</accession>
    <name>C7PZI0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786930.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2722"/>
    <dbReference type="EnsemblBacteria" id="ACU71637">
        <property type="protein sequence ID" value="ACU71637"/>
        <property type="gene ID" value="Caci_2722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2722"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_0_2_11"/>
    <dbReference type="OMA" id="CYSLIIG"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="45160" checksum="077A368344E34F70" modified="2009-10-13" version="1">MTPRPVVQPDDLDRVDLASPVLHAENNLDEVWRHLRANDPVHWHRPVDGRPGFWVITRHADVHKVYQDKGHFTTAGGNALATLLTGGDSASGTMLAVTDGPRHQQIRNVMTRGLNPRTLEAVRHSLQQTVDRLLKNALDMGECDAAHDVAANVPLGAICDLLEIPESDRHHLLGLTSHAWSTDHADEPPQEAWVAKSEILLYFSRLAKERRGAEYDDMVTLLANCRIKGEPLSATELMANCYGLMIGGDETGRHAITGTILALTENPDQWRALKNGDVDIKTATEEALRWTVPSLHGGRTATGDVELGGKLIKAGDVASVWIYSANRDEEVFDEPDRFLLGRTPNNHFTFAYGMHYCLGHYLGRMEVHAVLDGLRRLVGNVEQIGEEKWIYSSILHGMHSMPVRMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZN8</accession>
    <name>C7PZN8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793282.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4692"/>
    <dbReference type="EnsemblBacteria" id="ACU73553">
        <property type="protein sequence ID" value="ACU73553"/>
        <property type="gene ID" value="Caci_4692"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4692"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_11"/>
    <dbReference type="OMA" id="GDRPAWH"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="5">
        <location>
            <begin position="23"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="30536" checksum="5F8A45F7CAC260EA" modified="2009-10-13" version="1">MSGFDLLVVGDANPDVLVAGAPVVPPYGQAETLVASGTLALGGSAAIVAHGAARLGVSTALAAVVGRDAAGDFVLDALSSAGVDVGAVVRHPELATALTVCLGGPGGDRAILTAAGCLAEFEPGELPRARHIHAASYFLQPRLAARLPELFRGAAATCSLDTNHDPAGRWRLAAGLLEVCDYVLPNESEALALTGAATVDEALAAFAAAGVGTPVVKRGRHGAVARRAAETHTARLTPLEPVDTVGAGDSFDAGFLAAVLNGEDLDRALAVGCACGALSTQAVGGTAAQPSWEQAVAYASRPGISPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q063</accession>
    <name>C7Q063_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795285.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6710"/>
    <dbReference type="EnsemblBacteria" id="ACU75556">
        <property type="protein sequence ID" value="ACU75556"/>
        <property type="gene ID" value="Caci_6710"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6710"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039395_0_1_11"/>
    <dbReference type="OMA" id="MPDLFNY"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008993">
        <property type="term" value="F:rhamnulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019301">
        <property type="term" value="P:rhamnose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07771">
        <property type="entry name" value="FGGY_RhuK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013449">
        <property type="entry name" value="Rhamnulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0684">Rhamnose metabolism</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="73"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="259"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="51262" checksum="A7BC9500A2650196" modified="2009-10-13" version="1">MSGGTETGTTGTVAAVDLGASSGRVMVARVGTDCLKMREAHRFENRPVRVGGTLYWDALALYQGIVDGLRAGGQVASIGIDSWAVDYGLLDADGALVGNPVHYRDARTEGVAERAWKTVPAEALYAVTGIQHAPFNTLYQLIAARGTGALAAARQALLIPDLMAYWLTGIAGTEVTNASTTQLLDASSRTWSADLAGRLGVDVGLFPPLRQPGARIGDLLPAVLEAAGLRGPVPVTAVASHDTASAVVAVPAAAGERFAYISTGTWSLAGLELEHPVLSEASRAANFTNEAGIDGTIRYLRNIMGLWLLQECVREWRVELPALLAAARKVPGLRSVIDAADATFLAPDHMPDRIREACRATGQPVPNTPPEITRCILDSLALAHRRAIEDAQRLADQPIDVVHMVGGAVRNTLLCQLTADACGLPVVAGPTEAAALGNVLVQARALGLLGDRTEMRALVARTQSLTRYVPGGDRAAWDEAAARLSGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q078</accession>
    <name>C7Q078_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hyaluronate lyase</fullName>
            <ecNumber evidence="4">4.2.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.1" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795300.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6725"/>
    <dbReference type="CAZy" id="PL8">
        <property type="family name" value="Polysaccharide Lyase Family 8"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75571">
        <property type="protein sequence ID" value="ACU75571"/>
        <property type="gene ID" value="Caci_6725"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6725"/>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004172_4_1_11"/>
    <dbReference type="OMA" id="HQEKDYT"/>
    <dbReference type="OrthoDB" id="941406at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030340">
        <property type="term" value="F:hyaluronate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="PTHR38481"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_8_N" evidence="3">
        <location>
            <begin position="44"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8" evidence="2">
        <location>
            <begin position="301"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="576" mass="63283" checksum="98ADDDD19A429689" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0B6</accession>
    <name>C7Q0B6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8633</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8633"/>
    <dbReference type="EnsemblBacteria" id="ACU77449">
        <property type="protein sequence ID" value="ACU77449"/>
        <property type="gene ID" value="Caci_8633"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8633"/>
    <dbReference type="HOGENOM" id="CLU_1649071_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982662" evidence="3">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17285" checksum="DEB160F0115FEB93" modified="2009-10-13" version="1">MRLVRVCVAFVALQVAVVTVMPARVRGITAGLLTMVTVVVVITVAMEASFKRAEVRAAEAAPRSASRSGSRVGELPRRPRERFSPLIQRAYYLARNDSSASHIARSCDIPEAFAVLIIDDVRRTAPRKGRAARNASGRAARNSSGRAHSDGRKPKNPPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q183</accession>
    <name>C7Q183_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787051.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2849"/>
    <dbReference type="EnsemblBacteria" id="ACU71758">
        <property type="protein sequence ID" value="ACU71758"/>
        <property type="gene ID" value="Caci_2849"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2849"/>
    <dbReference type="HOGENOM" id="CLU_1861605_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="13958" checksum="C13116F4F761026E" modified="2009-10-13" version="1">MAWMQCRSCSTKFAVGLLRCPQCDAVSELYAVPEEVIEAEQEQEAAVPKISVEGGPSNALGLPAEEETSAVETETEGTAPEATEAAAQAEPETSDATSAATDEEPDSGEGAAGVDKPEAAPAPKPAKKAAAKKAVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1A9</accession>
    <name>C7Q1A9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4777"/>
    <dbReference type="EnsemblBacteria" id="ACU73638">
        <property type="protein sequence ID" value="ACU73638"/>
        <property type="gene ID" value="Caci_4777"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4777"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066396_0_0_11"/>
    <dbReference type="OMA" id="NNEKPVG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="2">
        <location>
            <begin position="130"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30116" checksum="D7A7460392F73074" modified="2009-10-13" version="1">MSSDSVAGEEMLREEASGEQTAGEVMAGGVNTVLRIGDRVHRPAGEWTPTVHALLAHLASKGFTAAPRAHGFDAEGREVVDFVVGDVPGSEVVVSDEALADMALLLRGLHDASTDFVPPAGASWYFEPREPAEVICHGDVAPYNTVFRDGRPVALIDFDTAHPAPRVWDVAYAAYRFVQLVDEDAEAEAVVGEQARRLALFADAYGLGARDRAAVVGMVVARLRHLIGFMRRQAAAGHPGFGRHVAEGHDGYYLRNIAYVERHRAAFDAALAGRDSSGNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1T5</accession>
    <name>C7Q1T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6795"/>
    <dbReference type="EnsemblBacteria" id="ACU75636">
        <property type="protein sequence ID" value="ACU75636"/>
        <property type="gene ID" value="Caci_6795"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6795"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_11"/>
    <dbReference type="OMA" id="KARKYEV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="25906" checksum="781CA485BA17A9C7" modified="2009-10-13" version="1">MMIKVLVVDDEPQLLRALRINLTARKYEVVTAIDGTSALAIAARTLPDLVVLDLGLPDLDGAEVIKGLRGWTEVPIVVLSGRADASDKVEALDAGADDYLTKPFSMEELLARLRVARRHADRNTPKTAVQRVGDFDVDVASHTITRVPEAPETVPPTVHLTPTEWGIVEVLLKNTGRLVSARQLLTEVWGHGYENDTPLLRFHFTKLRRKLEREPSRPAHLLTEPGMGYRFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2K5</accession>
    <name>C7Q2K5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7 8">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplJ</name>
        <name evidence="9" type="ordered locus">Caci_0915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785142.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0915"/>
    <dbReference type="EnsemblBacteria" id="ACU69847">
        <property type="protein sequence ID" value="ACU69847"/>
        <property type="gene ID" value="Caci_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0915"/>
    <dbReference type="eggNOG" id="COG0244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092227_1_0_11"/>
    <dbReference type="OMA" id="VRDQKQA"/>
    <dbReference type="OrthoDB" id="1470978at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002363">
        <property type="entry name" value="Ribosomal_L10_eubac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01109">
        <property type="entry name" value="RIBOSOMAL_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="17850" checksum="5EFF7685F4B7A28C" modified="2009-10-13" version="1">MARPDKAAAVAEIADHFRGSNAAVLTEYRGLTVAQLKELRRALGATTDYAVVKNTLTKVAAQEAGIDGLDVAALKGPSAIAFIKGDPVEAAKGLRDFAKANPLLVIKGGVMEGKTLTPADITKLADLESREVLLAKAAGAMKASLANAAALFQAPLAKAVRTVDALSAKKSADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U6</accession>
    <name>C7Q2U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787131.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2929"/>
    <dbReference type="EnsemblBacteria" id="ACU71838">
        <property type="protein sequence ID" value="ACU71838"/>
        <property type="gene ID" value="Caci_2929"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2929"/>
    <dbReference type="HOGENOM" id="CLU_1370035_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="21552" checksum="0184C8AC03233988" modified="2009-10-13" version="1">MVDLLLDERTILIYLAAAADSGNAEHVSLKGILGPDKADLPREQFDSSDWERMADLYFAVRNLLMLGLVGGIAADGGEHLNRFRITDAGRDELAANAKESKRRTTDPAFGGFRVGENPWITHWRWVAVGKGVVLDDLQKMHQNETRGGVPTGKCLCGLPVPCSTAERIGVYAAGLRDPCDCRRGGGGACPMIDRSEADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U9</accession>
    <name>C7Q2U9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787134.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2932"/>
    <dbReference type="EnsemblBacteria" id="ACU71841">
        <property type="protein sequence ID" value="ACU71841"/>
        <property type="gene ID" value="Caci_2932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2932"/>
    <dbReference type="HOGENOM" id="CLU_2092388_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12878" checksum="0F043DE20134F23F" modified="2009-10-13" version="1">MNYSATARLTCLLKESANNPSILPPGVGPDVHTVLVENGELRDALAVAVELLDRLADNDGCEYDHNDDCQMHNLHQRPCPHPLARQIVAAWRKVELERIERVSALDDDLDEVANPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2X5</accession>
    <name>C7Q2X5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787160.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2958"/>
    <dbReference type="EnsemblBacteria" id="ACU71867">
        <property type="protein sequence ID" value="ACU71867"/>
        <property type="gene ID" value="Caci_2958"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2958"/>
    <dbReference type="HOGENOM" id="CLU_2492157_0_0_11"/>
    <dbReference type="OrthoDB" id="969846at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="9812" checksum="7CB6C5CDA19BDFC7" modified="2009-10-13" version="1">MTEPPDDLTRQVRAQIAAAYGLDYDTTDWNWDGYLTARAEYDARLAEFRDAIPKRMEASATDLTALFQAEDLLPPGFTFAYEDRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3I7</accession>
    <name>C7Q3I7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6918</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795480.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6918"/>
    <dbReference type="EnsemblBacteria" id="ACU75752">
        <property type="protein sequence ID" value="ACU75752"/>
        <property type="gene ID" value="Caci_6918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6918"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002352_0_2_11"/>
    <dbReference type="OMA" id="QPWQGHE"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="4">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="726"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="772"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="818"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="864"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="910"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="951"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1127"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1173"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1334" mass="141551" checksum="1549F56F6EDC831F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3T9</accession>
    <name>C7Q3T9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797421.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8884"/>
    <dbReference type="EnsemblBacteria" id="ACU77697">
        <property type="protein sequence ID" value="ACU77697"/>
        <property type="gene ID" value="Caci_8884"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8884"/>
    <dbReference type="eggNOG" id="COG1725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_10_1_11"/>
    <dbReference type="OMA" id="MVEFRID"/>
    <dbReference type="OrthoDB" id="1860081at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="15529" checksum="0871106AC7DD2BC2" modified="2009-10-13" version="1">MIDFHVDRAGSVPAYAQLVQQVREALRLGLLHPGDKLPTVREVVTSCAVNAATVLKAYRELELSGLVEARQGAGTYVSGTLGGAADQAVMDELRGRLTGWVGDARTAGLEDDDMRALMTSVLAEPPGELTAEQRAASAPSQDRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q475</accession>
    <name>C7Q475_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ordered locus">Caci_1007</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1007"/>
    <dbReference type="EnsemblBacteria" id="ACU69935">
        <property type="protein sequence ID" value="ACU69935"/>
        <property type="gene ID" value="Caci_1007"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1007"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_2_0_11"/>
    <dbReference type="OMA" id="EVKYSGE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10711" checksum="C08D4D47EC432751" modified="2009-10-13" version="1">MATVAIKPLEDRVVVKPLDAEQTTASGLVIPDTAKEKPQEGVVLAVGPGRWEDGKRVELDVKEGDIVLYSKYGGTEVKYNNEEYLVLSARDLLAIVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4D8</accession>
    <name>C7Q4D8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785292.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1072"/>
    <dbReference type="EnsemblBacteria" id="ACU69998">
        <property type="protein sequence ID" value="ACU69998"/>
        <property type="gene ID" value="Caci_1072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1072"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="RDGITMR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="33123" checksum="DCE08E9CFD802765" modified="2009-10-13" version="1">MAIDIRLMRYVVAVAEEGGFQRAAKRLLVAQPSLSRQIRDLERELGVTLFERKPAVRPTDAGCVFVESARTVLAETDRLIERTMLAGRGELGTVRVGYIHSAVLDTVPRVVAAMAERHPGVTVDLRENWTPDLDTALLAGEYDLVLSRDMPPRPEYQRETLRPEGLVAVVGESHPLAGREAVALREFAGQRFCHPQHNLAPGRHAYMINALRQSGETFEYRESPVHGLSHLDLADGHSFALVPDSAVGRVPVGTATIVITDDLPRLTLEMVWRRDAVSAALGVLVSTARELARREGWFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J3</accession>
    <name>C7Q4J3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787255.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3053"/>
    <dbReference type="EnsemblBacteria" id="ACU71962">
        <property type="protein sequence ID" value="ACU71962"/>
        <property type="gene ID" value="Caci_3053"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3053"/>
    <dbReference type="HOGENOM" id="CLU_1988618_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="13203" checksum="633CD3AB1E29EB61" modified="2009-10-13" version="1">MTALIEQAANDALADDHNRLAPALDVAVKVHMLLEGVSLASWTVLPGQVLGQLSKPDEATVIGQVAWLSRQPGWSLVQSPMKTSPFIAPWIELSAVTEMDGVTVRLWTTITADILSVSATTGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Z3</accession>
    <name>C7Q4Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5081"/>
    <dbReference type="EnsemblBacteria" id="ACU73941">
        <property type="protein sequence ID" value="ACU73941"/>
        <property type="gene ID" value="Caci_5081"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5081"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="MIPGTED"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="275" mass="29262" checksum="C018AA4C350EE1A2" modified="2009-10-13" version="1">MRYFVAVAEELHFRRAAERLFISTPTLSQQIKAVEREIGGPLLIRRPEGVSLTPAGEVLLRAARQVLAAADDAVRATREAAGTAAPVLRFGLLNGVPPRLIERITSRLDERVDSRLDMTSGTTAELARLLEAGRLDLVMLRAPVDLPPQLRSVHVASEELGVLMSEQHDLAGSASVTLADLAGREMVLFPRASAPQLHDSVLAALDGVVLSTSAMGYAPMLAVLPLRPDVFGLSSARAAGVAGLAWRPIEGRPLVVEYVAAWSAHNPRAAALVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q547</accession>
    <name>C7Q547_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75816">
        <property type="protein sequence ID" value="ACU75816"/>
        <property type="gene ID" value="Caci_6986"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6986"/>
    <dbReference type="HOGENOM" id="CLU_1902907_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="15065" checksum="016DC54A56C4101D" modified="2009-10-13" version="1">MHQEVPVTSLNSAVIELLGRPNMLGEDRALAARMIVADGEINHILARTKGILARPIWAGCAHESDRCNDLFVAEWERFKSRVADDTEFRRHPSPSERDVFKEAVAGTEYALARLRQEFAQLGKTSWVYDDEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q597</accession>
    <name>C7Q597_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795594.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7036"/>
    <dbReference type="EnsemblBacteria" id="ACU75866">
        <property type="protein sequence ID" value="ACU75866"/>
        <property type="gene ID" value="Caci_7036"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7036"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_3_1_11"/>
    <dbReference type="OMA" id="ALMGDGI"/>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="268"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="30524" checksum="E2E3A4CC1348C3CE" modified="2009-10-13" version="1" precursor="true">MLSDTIFSLPFMQRAFLAALAIGLAAPAIGTYLVQRRLALMGDGLGHVALTGVGLGLLTKTSPVWGAVLVAVVGAAAVELIRERAKASGDVALAMLFYGGLAGGSMLISLSGGNANLNSYLFGSILSTSVGDLWAIAALAVGVLVVTLGLRRALFAVCQDEEFARVAGLPVRALNLLMAVTTAVTVTVGMRVVGVLMVSALMVVPVAAAQQLTRAFAATMGAAMVVGVGAAFSGVTMSYYADTPPGASIVLIAIAVFMIASISAGLVRRGHGRSGSGARPRTREPDPTAEQAVATGRSLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5G2</accession>
    <name>C7Q5G2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Beta-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7101</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795659.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7101"/>
    <dbReference type="CAZy" id="GH35">
        <property type="family name" value="Glycoside Hydrolase Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75931">
        <property type="protein sequence ID" value="ACU75931"/>
        <property type="gene ID" value="Caci_7101"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7101"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007853_7_2_11"/>
    <dbReference type="OMA" id="EMKPAFM"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="8">
        <location>
            <begin position="14"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="582"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="625" mass="68641" checksum="3FB4DF01E890B779" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5L2</accession>
    <name>C7Q5L2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage/plasmid-related protein TIGR03299</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_9010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797547.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9010"/>
    <dbReference type="EnsemblBacteria" id="ACU77823">
        <property type="protein sequence ID" value="ACU77823"/>
        <property type="gene ID" value="Caci_9010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9010"/>
    <dbReference type="eggNOG" id="ENOG502Z7QU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058825_0_0_11"/>
    <dbReference type="OMA" id="GGRKFWA"/>
    <dbReference type="OrthoDB" id="1540547at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026325">
        <property type="entry name" value="DUF932"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017686">
        <property type="entry name" value="Phg/plasmid-like_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06067">
        <property type="entry name" value="DUF932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03299">
        <property type="entry name" value="LGT_TIGR03299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="36874" checksum="479BA1844FC75387" modified="2009-10-13" version="1">MAHLLERFRDGTTAFASARENAWHRLGTVTRDAMTAEEALTTAFLDGWNVRKIPVAGKEITEHGVTTVDSPDRFMTVRTNPKTRRTDYLGIVGSDYTPVQNEENCQIMNTLVDASGAHFETAGSLREGRQVFVTMRLPETMTVAGTDRLDLYISGLNSHDGTGAYKLIVTPIRIVCANTQSLALDRARSSFSIRHTESAKKKIAEARKALGLMFKYVEEFEKAAERMINETLTLAEFEKVCHELWPLEPNAGPRTKSNDAKRMGHLRRLFEYAPTNANIRGTRWAGVQAIGEYLDHYAPAKTDVVRAHRVLTSSEVTTRKHEAHRLLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T2</accession>
    <name>C7Q5T2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PEP-utilizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1103</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785323.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1103"/>
    <dbReference type="EnsemblBacteria" id="ACU70029">
        <property type="protein sequence ID" value="ACU70029"/>
        <property type="gene ID" value="Caci_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1103"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_0_11"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="6">
        <location>
            <begin position="8"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="4">
        <location>
            <begin position="155"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="5">
        <location>
            <begin position="253"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="564" mass="58813" checksum="4F61DA405FF13E13" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5X1</accession>
    <name>C7Q5X1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1142</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785362.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1142"/>
    <dbReference type="EnsemblBacteria" id="ACU70068">
        <property type="protein sequence ID" value="ACU70068"/>
        <property type="gene ID" value="Caci_1142"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1142"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_43_2_11"/>
    <dbReference type="OMA" id="GYDLTEP"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="21959" checksum="90C3FB7D5D1F6C72" modified="2009-10-13" version="1">MARAGLSPEVLVTAAAELADEIGFENVTIGVVARRFGVREPSLYSHIRNANDLRVRVAAKALGDLADQLSEALAGRSGREALLAFAAAYRDYGRDHPGRFTAARMPFPLDSPAADAARRHSELTRALLRGYALGEPDETDAVRLLGATILGFVTLEAGGSYRHHPRSADASWNAAMDALDVALRNWPTAEEKASAGAKSPKPGKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q605</accession>
    <name>C7Q605_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1177"/>
    <dbReference type="EnsemblBacteria" id="ACU70102">
        <property type="protein sequence ID" value="ACU70102"/>
        <property type="gene ID" value="Caci_1177"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1177"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_4_11"/>
    <dbReference type="OMA" id="PMLEATF"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="32409" checksum="6A5B9A5DEAA39A58" modified="2009-10-13" version="1">MLPPVVLGIDFGGTKTAMAVAEPTPGPRLGAATVPTHAAEGGRASLGRGLRAARALLDRVAPGREPIAVGVSTIGIPRDSGVDLAPNIPGWADLALAKEIQAAFPASEVRVETDVKAAARVEAVEGALQEADPGLYLNLGTGLAVAIVTKGEVIAGRNGAAGEIGYNLRRLADVGLAAGHRSILEDQVSGIGLLARAKEIHPDATGAKDLFAAASLDPRAADILREFTDELAFHLVNLAIAVDPARIAVGGGMVRSWPVLYAPLRRALDAAVPFPPELVQAAFPFDAPLAGALTLARAAVREAALAAPAESSTTSTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P6</accession>
    <name>C7Q6P6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5222"/>
    <dbReference type="EnsemblBacteria" id="ACU74081">
        <property type="protein sequence ID" value="ACU74081"/>
        <property type="gene ID" value="Caci_5222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5222"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="429" mass="43476" checksum="8E4D59773CD5B17D" modified="2009-10-13" version="1">MIHRTQPEESIVAAPPNLREEGRLRVLQVLLASTTTSRPELVRLTGLSRATVSVLVADLISAGLVVEENGANGSGGSSGSSGSGGSSGTPEAESRSMGRPALPLALNRSVAYAIGADIGHAHVRVALCDLHGTPVWETSRAKEVDRAPHETLDLAADLVRRALTENGVSGERVLGLGVGIAAPVDADGALSAEGIMPGWTGIRPGPELERRTGLATELTNDANAGALAEHMYGAGRDIEDMVYIRLSAGIGAGVIAAGRLQRGAGGLAGEIGHLPAVRDGLVCRCGNRGCLETIASPVAVARLLQDSWGEPVAPGDLPALLAAGTPGTARVVEDTGEAVGRALAGLVTLLNPRLIVVGGDLAAIGEPLFEPLRRGIARYALPSAARQVAVVAGRLGSSAEVRGAAARVLAGAAQTLAVMSGAEAAELLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7C4</accession>
    <name>C7Q7C4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1287</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785506.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1287"/>
    <dbReference type="EnsemblBacteria" id="ACU70212">
        <property type="protein sequence ID" value="ACU70212"/>
        <property type="gene ID" value="Caci_1287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1287"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_11"/>
    <dbReference type="OMA" id="LGMPAFW"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="117"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35532" checksum="0D271A645BAB5DD2" modified="2009-10-13" version="1" precursor="true">MTTFLLRRAVTALILMLGVVMVTFVVFYVVPALGGRTTDQLAAQFASRDPSPEQLLLIKHRLGLDQPLYAQFWDYLKAMVVGMNLPPGSGASHCSAPCLGYSWRLHDSVLALILDRLPVTVSIAIGAAVLWLVLGVAGGAASAVSPGGAADRVIRIAALLGVCLPVVFIGPLARSQLAWLFPSVSYYSFLHNPFIWADHLILPWVTLALGYFALYTRLTRSGMIEALSGQFIRTAQAKGLPGRRVLWQALRTTLPTVATVFAMDLGLLLGGAVLAEKIYGLHGIGDLAQNGVDGQDLPVVLGVTLFAGLFIVVANFAVDAAYAVLDPRIRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K0</accession>
    <name>C7Q7K0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787486.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3286"/>
    <dbReference type="EnsemblBacteria" id="ACU72193">
        <property type="protein sequence ID" value="ACU72193"/>
        <property type="gene ID" value="Caci_3286"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3286"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_11"/>
    <dbReference type="OMA" id="IAVYRHQ"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20980" checksum="B7496B0453078282" modified="2009-10-13" version="1">MPTEQEPARSKRSDALRNQQTLLAAAAEVFVTSGVDAPIRQIAAKAGVGVGTFYRHFPTRADLITAVYRHQIEECAEAGPTLLASADSPFEALRRWIDMFTDFLVTKHGLADALRSDDATFAALHTYFLDRLEPVCANLIEAAVAAGDIRGDISAYELMRGVGNLCVGRDLDARYEPRRLIAVLLDGLHAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K8</accession>
    <name>C7Q7K8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3294</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3294"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH87">
        <property type="family name" value="Glycoside Hydrolase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72201">
        <property type="protein sequence ID" value="ACU72201"/>
        <property type="gene ID" value="Caci_3294"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3294"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009451_0_0_11"/>
    <dbReference type="OMA" id="GAMNPNW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd14490">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033801">
        <property type="entry name" value="CBM6-CBM35-CBM36-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="Pectate_lyase_SF_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pectate_lyase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00231">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982882" evidence="2">
        <location>
            <begin position="43"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="710"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="959"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1109" mass="111447" checksum="5CC304483987B359" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7W9</accession>
    <name>C7Q7W9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793865.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5277"/>
    <dbReference type="EnsemblBacteria" id="ACU74136">
        <property type="protein sequence ID" value="ACU74136"/>
        <property type="gene ID" value="Caci_5277"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5277"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_0_0_11"/>
    <dbReference type="OMA" id="KRMLKMH"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="34387" checksum="64FA9BDBC73104B5" modified="2009-10-13" version="1" precursor="true">MTDTTAAGSRRPPLIGALRWDTVVGALLVILLAVSFSTVNGFSNALNISFLIGNTLPVAAIALPMTMLVASGEIDLSVGSTVGLSGAVMGALWNHGMNINAIIVICAALGIVCGLVNALLVTKLGLPSLAVTIGTLALYRGVAQIVLGSNSVTDFPQNYLNFGSGRLGGSFLPTAVIPWLVLAVLAAVVLHATGFGRSVFAVGASAEAAWFAGVRVKRVKLSLFVATGLVSSLTGVFWVLHYASATYSNATGLELSVVAAVLLGGVDFDGGRGTLGGAIAGVFLLGTMQNVMSLADVSAQSQTVVTGVLLTVSVLGPRVARQVFARQARLQPLRGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8E6</accession>
    <name>C7Q8E6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76134">
        <property type="protein sequence ID" value="ACU76134"/>
        <property type="gene ID" value="Caci_7305"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7305"/>
    <dbReference type="HOGENOM" id="CLU_2988188_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="57" mass="6142" checksum="799CA840FAB46674" modified="2009-10-13" version="1">MGLGLGVCLGLCLGGRLSLVALRRLLALVLLSLRLGLCLCLRLPLRSLRSLRSLRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8E7</accession>
    <name>C7Q8E7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7306"/>
    <dbReference type="EnsemblBacteria" id="ACU76135">
        <property type="protein sequence ID" value="ACU76135"/>
        <property type="gene ID" value="Caci_7306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7306"/>
    <dbReference type="HOGENOM" id="CLU_1955664_0_0_11"/>
    <dbReference type="OMA" id="DELVHAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_7" evidence="2">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="128" mass="14215" checksum="55485434E015FFD1" modified="2009-10-13" version="1">MAATWADSPEPAEPRARSQCRTLRQLANSDTDELVHAWEQGVGVAEIAARSGIHRSTVWRHLRNRGIDASDRSMGPNGLTRAIELYAEGRTLVQIAREFGVAKKTIRKRLVEGGVVIRRGGRASWESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8I3</accession>
    <name>C7Q8I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_7344</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7344"/>
    <dbReference type="EnsemblBacteria" id="ACU76171">
        <property type="protein sequence ID" value="ACU76171"/>
        <property type="gene ID" value="Caci_7344"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7344"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_4_0_11"/>
    <dbReference type="OMA" id="KWLTQGM"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="33085" checksum="4CB2ABCA9B764E1D" modified="2009-10-13" version="1" precursor="true">MSAMTTGQAVAEQAAGRTAGQSVETAKAAEGTTEAMGRQRATLSEIWRIGRIRMVIEVVQLRRNTGLLIYTFAVPVVMLLLFGSIFRGDIEGTSATYQQVYVTGMTGMCVINGALQNLAYQVAAERHTKALKRLRTTPMPAASYFLGKVASVLAATVAQVAVMLLVGVTVMGLKLPTSVGPWLTFTWVLLLGCTACSLLGIGMSGLIRSENGSAIVWLPVMVLQFISGVFIVFSQLPKPVQQVGAVFPIKWLCQGMRSVFLPDSFKYSEPAQSWEHGRLALVLAAWCVVGLMLCLKTFTWRGRDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T6</accession>
    <name>C7Q8T6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785645.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1428"/>
    <dbReference type="EnsemblBacteria" id="ACU70351">
        <property type="protein sequence ID" value="ACU70351"/>
        <property type="gene ID" value="Caci_1428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1428"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049749_5_0_11"/>
    <dbReference type="OMA" id="AGWYTSQ"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="25146" checksum="0FDB43DD73F4BA7C" modified="2009-10-13" version="1">MPTDTSYHGDLGDFFAGTGQQHPTNAYIDRPAMLELIGDVAGRDVLDAGCGPGFYAAAMADRGARVTAIDGSAEMVRIAARAAGERGTFARHDLELPLPFADASFDLAVMALVYHHLYARGQVLAELRRVVRPGGRLLVSTTHPMSEQRWLGGSYYQGGRVDAPIGGPGSGYTISFERMTVETFVNEMLDGGFVLERLVEPRPSVALRDVDPEKFAQLDVKPTVLAVALRRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W2</accession>
    <name>C7Q8W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785671.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1454"/>
    <dbReference type="EnsemblBacteria" id="ACU70377">
        <property type="protein sequence ID" value="ACU70377"/>
        <property type="gene ID" value="Caci_1454"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1454"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_2_11"/>
    <dbReference type="OMA" id="WVSRYAV"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="36244" checksum="7749591A9FD58972" modified="2009-10-13" version="1">MSEATTMSDAAETVPAERPARFARPSTRWLREFSLLPAMALLILIGFIESPDFLTGDNFLAMLQQSTELSVLVLAEALILISGRMDLSLESTVTLAPVIALWLVLPTSGNRFNGLGFGAAWMAIPICLLVGAAVGTINGFLILKMNLNGFVVTLGMLTMLHGLVIVIDGGQTIFTLPPSFSYLGRTEWAGQPASVWICGILFAVGIVALGWYRHGRGLYAIGGNPGAAKAAGIRVERTVWIVLIIGSMLAAFAGMLYTGRLGSASASAGTGKIFEVFAATVIGGVSMNGGRGSLFGALTGVLTLKLIENVLTFGHVSANDIEFFNGVVILVALIVSRYTSGAAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X0</accession>
    <name>C7Q8X0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787583.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3384"/>
    <dbReference type="EnsemblBacteria" id="ACU72290">
        <property type="protein sequence ID" value="ACU72290"/>
        <property type="gene ID" value="Caci_3384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3384"/>
    <dbReference type="HOGENOM" id="CLU_1122976_0_0_11"/>
    <dbReference type="OrthoDB" id="1740922at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="3">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="26113" checksum="807538148C83B416" modified="2009-10-13" version="1">MSSRNRTAPRDPDHSAENSEALAAYVLNALEPEQQQAVQQHLQDCDLCYLEYTSLGVLPGLLDSLSLEDIRELTDTVATEQSSAATARPERAERPDRTERPARPWTRRRRALLAGGAFSAAMVATGFAPAYADSIPAAPSAQPGETARSAADAQTTAVGLAVSAEPLPDDQTALDVEVRSPRALRECVLEVTTDDGAIIEACHWAGTPSTRVVFSGDIPLAAARLRAVAVLAGDGTVLARQDLSAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Y2</accession>
    <name>C7Q8Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787595.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3396"/>
    <dbReference type="ESTHER" id="catad-c7q8y2">
        <property type="family name" value="A85-Feruloyl-Esterase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72302">
        <property type="protein sequence ID" value="ACU72302"/>
        <property type="gene ID" value="Caci_3396"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3396"/>
    <dbReference type="eggNOG" id="COG0627">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037589_0_0_11"/>
    <dbReference type="OMA" id="HEGAEYL"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28680" checksum="256CA946BD5C7E2F" modified="2009-10-13" version="1">MMEIIQASFPAKSVGGDVDYRVLLPPDWKQGEQLPLVVHLHGAMSSSASLEAAKPLYEEVFEQGGFPRAVIACPSTPTAEGFYIDWPDGAAWETLVSDEFPEHLAATRGPFTATALIGASMGGYGVLKTAFCDPDRFTAVAAVSPAVFPGETPESVPEANIPSVLGDLHRAMAHGSNDPDTYVGNSVHGRARRNADRIRSRALPILVDCGAADEFLLHEGAEYLHQVLEELDIIHEFRLVEGAGHVGPAADARTRDAIRFLGAALIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q903</accession>
    <name>C7Q903_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72323">
        <property type="protein sequence ID" value="ACU72323"/>
        <property type="gene ID" value="Caci_3417"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3417"/>
    <dbReference type="HOGENOM" id="CLU_1783390_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15275" checksum="47E629CEEAC96334" modified="2009-10-13" version="1">MPSPNGRIAKRATRAIPSPLLRWTARAAVRVVLPIAGAAATVVVQRAKWRFGLWRSPHGAVVVDINRDVHALAPEGGRPVAALAALAERADLTLGGVPGRPVTRLRAVPRYPGDDIRADVALAKQHLEALEAGDPGLRLPPPAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q963</accession>
    <name>C7Q963_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Siderophore-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787676.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72383">
        <property type="protein sequence ID" value="ACU72383"/>
        <property type="gene ID" value="Caci_3477"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3477"/>
    <dbReference type="eggNOG" id="COG2375">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040923_3_0_11"/>
    <dbReference type="OMA" id="VHAFVHG"/>
    <dbReference type="OrthoDB" id="1630289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31633" checksum="C3160C21A39888A8" modified="2009-10-13" version="1">MTERPERGAGGRRRGAPPRLAHVQRVERVTPHMIRVVLGGPGLEGLEADQYTDHYVKILFPLAGVEYPEPFDMQQVREEMPRELWPSVRTYSVRAWDAAKLELTIDFVYHGDEGIAGPWAARAQPGDPVRFSGPGGGYAPDPDADWHLLAGDESALPAIAAALERMPEGARVHAFIEVSDSAEEQKLETGADATITWLHRGDAPAGKTLVDAVSGFDFPEGAVHAFVHGEAGFVKELRRLLFIERGVPRDQVSISGYWRLGHDEDGWQAGKRAWNAQVEADQDGTGTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9H3</accession>
    <name>C7Q9H3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794048.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5460"/>
    <dbReference type="EnsemblBacteria" id="ACU74319">
        <property type="protein sequence ID" value="ACU74319"/>
        <property type="gene ID" value="Caci_5460"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5460"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="PFMGPQI"/>
    <dbReference type="OrthoDB" id="293754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="22"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="510" mass="53825" checksum="2EF56EA7416CDCD6" modified="2009-10-13" version="1">MSDQGSADGAAVGVLEPGAPSFISYDPAGGGEVATFPETSAEQVRAVVGEARQAFAWWSGLTWAEREQRLRKWAGAITRGLDDLCELMHRENGKPRGDAFLEAFLAIEHIGWAAGHARKVLHPRRVGTGLLMANHAATLEYQPLGVVGVIGPWNYPVFTPMGSIAYALAAGNAVVFKPSEYTTAIGKWIVDAFDQANPDAPHQVLRLITGTGPTGAALCESGVDKIAFTGSARTGRKVMAACAPSLTPVLMECGGKDAMIVAGDADLAKAADAALWGAMSNAGQTCVGIERVYVVDAVKDKFVTELTAQIQKLALAPGEGPDAAYGPMTMPSQIDVVRRHIDDAIAKGGTVVVGGSGAVRAPYVEPTVLLDTPEDSSAVREETFGPTITVKGVRDVEEAIQLANATDYGLGASVFARRGGTAIARRLRSGMTSVNAVIAFAGIPGLPFGGVGESGFGRIHGADGLREFTRPKAITRRRYSTPFEPATFARHPKTFTIMKKYAETRYGRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I8</accession>
    <name>C7Q9I8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794063.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5475"/>
    <dbReference type="EnsemblBacteria" id="ACU74334">
        <property type="protein sequence ID" value="ACU74334"/>
        <property type="gene ID" value="Caci_5475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5475"/>
    <dbReference type="eggNOG" id="ENOG5032TID">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112381_0_0_11"/>
    <dbReference type="OMA" id="IGNIDNF"/>
    <dbReference type="OrthoDB" id="1994921at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="19681" checksum="A300C8F933733A4A" modified="2009-10-13" version="1">MTTTENPIADGRHDFDFLAGTWKVEHRKLVAMADPHCTEWVEFEGVQWMRQTLGGLGNVDNLTIEKMPDGSRYEGMSLCLFDPESGQWSIWWASTIAPGRLDPPVKGRWTGTHGVFECSDTLEGTPIEVRLDWDAFDADTARWEQSFSFDGGQTWVHNWRMSFTRISHEALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9N7</accession>
    <name>C7Q9N7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7380"/>
    <dbReference type="EnsemblBacteria" id="ACU76206">
        <property type="protein sequence ID" value="ACU76206"/>
        <property type="gene ID" value="Caci_7380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7380"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_10_0_11"/>
    <dbReference type="OMA" id="VQEPWGA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010067">
        <property type="entry name" value="ABC_SsuA_sub-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01728">
        <property type="entry name" value="SsuA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981489" evidence="1">
        <location>
            <begin position="33"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="374" mass="38232" checksum="EE089424C06C2EB3" modified="2009-10-13" version="1" precursor="true">MIRRALSTVAATVAAGWMVVSLVIVVAAYVSASSDSSGSSTSSSSSNAAAGTASTAAGELRLGYFANVTHATAVVGVGHGDFAKALGSTKLSTQVYNAGPAEMTALLGGQLDAAYVGPSSALAAFAQSHGEALKVVAGATSGGAELVVRPGINSVADLKGKTIATPQKGNTQDVALRAWLKQNGLTANPDGTGEVSVNPQDNAATLDQFKAGHIDGAWLPEPWASRMVLEAGAKVLVDERALWPGGQFATTNLVVSTSFLKAHPDTVKALIDGQIAANQWITADPTDAQQLVNDQLKKLTGKALTGAEIQRAFTEQAVTDDPLAASLQTSMDHAVSTGLLKKTDLHGIFDLTLLNTELARDGRSAVSDAGLSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB3</accession>
    <name>C7QAB3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3506"/>
    <dbReference type="EnsemblBacteria" id="ACU72412">
        <property type="protein sequence ID" value="ACU72412"/>
        <property type="gene ID" value="Caci_3506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3506"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_23_7_11"/>
    <dbReference type="OMA" id="MANGEPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="63"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="61596" checksum="C11818B57EF0DF25" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAJ8</accession>
    <name>C7QAJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3592</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792226.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3592"/>
    <dbReference type="EnsemblBacteria" id="ACU72497">
        <property type="protein sequence ID" value="ACU72497"/>
        <property type="gene ID" value="Caci_3592"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3592"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_11"/>
    <dbReference type="OMA" id="RSAACKV"/>
    <dbReference type="OrthoDB" id="972769at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="9"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="36927" checksum="BD82B5E0DCEE0B19" modified="2009-10-13" version="1">MTSLAVRYTAARTLTTRPADTEPPGPGQVELAPAYVAICGTDLRIFHGDMDARVKAPAVIGHEMSGRVVRVGPGVEGYAPGDPVTVMPLSWDGTCLACRRGYRHICQNLAFIGIDSPGAMQQRWTVLASTLVRLPDSLALDRAALVEPTAVAVHDVARAGVSHGDRVLVVGAGPVGLLIALVARASGGEVRVVESNPQRRRLAEQLGLNAWDPTTDVVPERLRDWTQHTGADIAFETSGTEPGVQTAVDALAVRGRLCLVAMHPGLRPVDLHRFVWQEQTLIGARLYERADFETAARLIDAGTIPADQLISRIVPLIDALGAFESLEVGGDVKVLVDCGASVLERAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB25</accession>
    <name>C7QB25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alginate lyase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7491"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="PL7">
        <property type="family name" value="Polysaccharide Lyase Family 7"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76316">
        <property type="protein sequence ID" value="ACU76316"/>
        <property type="gene ID" value="Caci_7491"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7491"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_691930_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981519" evidence="1">
        <location>
            <begin position="49"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="49"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="42950" checksum="FCE2CD47310ECA05" modified="2009-10-13" version="1" precursor="true">MPTPTPTASPRMLRKPRRRSARSFAAAFGSVALTVAGTSLMLAPVASAGNATGQVTGYQGLCLDDRGGLTANLNPVQVYSCNGTTAQQWTVNSTGNTLQVLGKCLDVHSAGTANGTTVDLYDCNGSGAQVWVPQSNGELLNPNSGKCLDDTGHGGSGTQAQIWSCTGSTNQQWTLPTGSGGGTGPGGLNPGVAPGGNFDLSLWELQLPTGSAGSPTTILPAQLEGANGYQSQYFYTDSTDGAMTFWDPENGVTTPNSNYSRSEFREMTSSGAAANWFAAGTTNTLSATLKVTQVPDHVCVGQIHLGSGGSTKPLLELFYYASGDIKMAIEQTPAGGNEVLYDVGTVPVGTQFSYVIGLSGSTISLSLNGGAARTWTASSTFNGYGMYFKAGDYDQSSGSSSSVGARVGFYALSIHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBD8</accession>
    <name>C7QBD8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1594"/>
    <dbReference type="EnsemblBacteria" id="ACU70515">
        <property type="protein sequence ID" value="ACU70515"/>
        <property type="gene ID" value="Caci_1594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1594"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3415">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_372111_0_0_11"/>
    <dbReference type="OMA" id="NECVVIE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="3">
        <location>
            <begin position="388"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="754" mass="79697" checksum="A6172E4B077D850B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBG7</accession>
    <name>C7QBG7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ordered locus">Caci_1623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785838.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1623"/>
    <dbReference type="EnsemblBacteria" id="ACU70544">
        <property type="protein sequence ID" value="ACU70544"/>
        <property type="gene ID" value="Caci_1623"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1623"/>
    <dbReference type="eggNOG" id="COG0253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053306_4_0_11"/>
    <dbReference type="OMA" id="HVAMRVH"/>
    <dbReference type="OrthoDB" id="1921631at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="226"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="236"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="30823" checksum="30846863306E12FF" modified="2009-10-13" version="1">MILDGLPARTTLTKGHGTENDFVIVPDPDGTLEIAPSRVAALCDRRAGIGADGVLRVVRTARMPGYEDQAAEAEFFMDYRNADGSVAEMCGNGVRVFALFVTARGLVKGGGVGEPVEFAVGTRGGIKRVTLRATGENTADVTVDMGIPVFPTERGAVTVDVHGTPRDAVDVDMGNPHAVVFVDSTDDAGSLYEMPTVSPTGVYAEGVNVEFAADVAPRHLAMRVYERGVGETRSCGTGACAVMIAAARRDAADAGTEYTVDVLGGRLRFVERADGHLEMTGPAALVFDIMESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBK8</accession>
    <name>C7QBK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785879.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1664"/>
    <dbReference type="EnsemblBacteria" id="ACU70585">
        <property type="protein sequence ID" value="ACU70585"/>
        <property type="gene ID" value="Caci_1664"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1664"/>
    <dbReference type="eggNOG" id="COG0316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_5_0_11"/>
    <dbReference type="OMA" id="YQLYFDE"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="17"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="12791" checksum="52121842A55A2323" modified="2009-10-13" version="1">MTVQTETSQEATVAQGIILTAEAASKVKSLLEQEGRDDLSLRVAVQPGGCSGLRYQLYFDDRSLDGDVVAGFDGVNVVTDRMSAPYLEGATVDFVDTIEKQGFTIDNPNAGSSCACGDSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW4</accession>
    <name>C7QBW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family with aminotransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792312.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3681"/>
    <dbReference type="EnsemblBacteria" id="ACU72583">
        <property type="protein sequence ID" value="ACU72583"/>
        <property type="gene ID" value="Caci_3681"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3681"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_1_11"/>
    <dbReference type="OMA" id="WQSYVET"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="474" mass="50185" checksum="F0B64ADDFA9B0797" modified="2009-10-13" version="1">MAEVLVELDRAAGRLVAQLVAGLRDAVREGRLAGGTVLPPSRQLAAELRVSRGIVVEAYQQLVAEGYLLSRVGSGTRVAEGLVATAAGAVGATADAGSAAPPRYDLTPGSPDLSLFPRSAWLAAMRRAVSTLPNSDLGYGDPAGVLRFREEMAAYLSRVRAADAVPERIVALNGAAHGLALGLRALREDGHRVLAVEDPSGDRPRQILGISGLDLAWVPVDDDGLIVSELRKTAATVVHVTPAHQYPTGTALSPGRRAELVAWAREVDGIIIEDDYDAEFRYDRDPIACLQGLGPDRVLYLGTASKSLAPALRLGWALAPAPLAERLRALRKETDLGGPILEHVTLAELIASGAYDRHLRGVRRRYRERRDALAAALAERLPHWRVRGIAAGLHLLVDLPPAVDEEVLTTAARAHGVRVQPLAPMRCAPGPPGLVLGYAGLSPAHLAEAVRLLHAAARSCDAVGPASGKLIRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC30</accession>
    <name>C7QC30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792378.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3747"/>
    <dbReference type="MEROPS" id="G01.006"/>
    <dbReference type="EnsemblBacteria" id="ACU72649">
        <property type="protein sequence ID" value="ACU72649"/>
        <property type="gene ID" value="Caci_3747"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3747"/>
    <dbReference type="eggNOG" id="ENOG502ZAYC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076823_1_0_11"/>
    <dbReference type="OMA" id="SLNWAGY"/>
    <dbReference type="OrthoDB" id="1546331at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PTHR37536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983106" evidence="2">
        <location>
            <begin position="29"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25522" checksum="30F73C7F9C71D27A" modified="2009-10-13" version="1" precursor="true">MAHKAAIRRSVLALTGALPMMLPVTAAAAGTTFNAPMSGAISHVFHSSSNNWSGYAVTGKKFTSVSASWTQPAATCSSKTTYSSFWVGLDGDGSNSVEQTGSEVDCSSGRAQYYSWYEMYPAYPVNFSNTVRAGDHFTASVTNTGGANFTLVLTDSTQGWTHTINKTLNNPALASAEVIAEAPSSSSGVLPLTNYGTINFTAAKANGASMAGQNPDPITMASGSTTKATVSSISSSGAFSDTWHHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCN4</accession>
    <name>C7QCN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleic acid binding OB-fold tRNA/helicase-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796222.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7673"/>
    <dbReference type="EnsemblBacteria" id="ACU76497">
        <property type="protein sequence ID" value="ACU76497"/>
        <property type="gene ID" value="Caci_7673"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7673"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017999_1_1_11"/>
    <dbReference type="OMA" id="FYAIGVF"/>
    <dbReference type="OrthoDB" id="100199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="815" mass="87311" checksum="C895F6D3B3F2D61A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF0</accession>
    <name>C7QDF0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792472.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3845"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72743">
        <property type="protein sequence ID" value="ACU72743"/>
        <property type="gene ID" value="Caci_3845"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3845"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_302218_0_0_11"/>
    <dbReference type="OMA" id="EAQGYGF"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981557" evidence="2">
        <location>
            <begin position="46"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="38"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="183"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="987" mass="101305" checksum="E189525DAD18DB4C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK2</accession>
    <name>C7QDK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794355.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5768"/>
    <dbReference type="EnsemblBacteria" id="ACU74626">
        <property type="protein sequence ID" value="ACU74626"/>
        <property type="gene ID" value="Caci_5768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5768"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_2_11"/>
    <dbReference type="OMA" id="EYTISEY"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16221" checksum="9F7348811A1A8840" modified="2009-10-13" version="1">MATMTAAEHREQAKARYDAFLAACPSRQLLDRISNKWVTLVLAALGNGSPQQLGADCAGEPRAMRYSELARLLAGVSQKMLTQTLRSLERDGLVTRTVTPTVPVTVSYELTGLGLSLYETMRGVKSWAETHMDDVFANREGYDNRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDN3</accession>
    <name>C7QDN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5799"/>
    <dbReference type="EnsemblBacteria" id="ACU74657">
        <property type="protein sequence ID" value="ACU74657"/>
        <property type="gene ID" value="Caci_5799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5799"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034080_1_0_11"/>
    <dbReference type="OMA" id="YSATNDF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983052" evidence="1">
        <location>
            <begin position="20"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="212"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="449" mass="47717" checksum="FBBEC5759A49A636" modified="2009-10-13" version="1" precursor="true">MAAVLATSVVAATAVPASASGAGSSTDHRLDGVWRTDGYSSVLRITGGTFELYDTTAISCIRDTTDDGDGSVSTFTPGADPNHALWHIDANVNARKLIRLPSLPPACTTPTPATPIETFDVFWRTFAENYPFFAQRGIDWNQVYATYRPQVTASTTNAQLRDIFAAMITPLHDAHVGLVADGTPVFSPKPGTQVPDGDLDARALALVQHADLSTATSALQTWCQGRVAFTTLPGGVGYLRVSDFTGFTSDDTSAANAAAFSAALDAVFTPDRTAGPNRLHGLVLDLRINGGGDDPLGLMLASRLTGHTFFAYAKQTRDDPTDPDRFTVPQPFLVHPSTTPHYTGPLSILAGGSTFSAGEAATQALLNRSPRPALVGDNTQGVFSDILDRQLPNGWMFGLPDEEYLTLSGRTYDIAGIPPDVKVPTFTPEQFADGTDPAFQVALQSLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDP8</accession>
    <name>C7QDP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794401.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5814"/>
    <dbReference type="EnsemblBacteria" id="ACU74672">
        <property type="protein sequence ID" value="ACU74672"/>
        <property type="gene ID" value="Caci_5814"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5814"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_2_1_11"/>
    <dbReference type="OMA" id="EWLVVLS"/>
    <dbReference type="OrthoDB" id="1292067at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="21179" checksum="93F524246C7D9B9B" modified="2009-10-13" version="1">MTQEPDMDALVRRRIRTLRLARGWTLDSLASRCDLSPSNLSRIETGQRRIALDQLVPIARALGTTLDQLVEPGDDTGVVIRPEPVQTPGMTTWLLSNERSPNGATVAKMRITAERPAGPEHLRVHPGRDWFTVLSGTAELHLGDRVILVQAGNAAEFTTMTPHLIAAHGSAVEILTILDHDGERAHRHDCEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE24</accession>
    <name>C7QE24_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7788"/>
    <dbReference type="EnsemblBacteria" id="ACU76612">
        <property type="protein sequence ID" value="ACU76612"/>
        <property type="gene ID" value="Caci_7788"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7788"/>
    <dbReference type="HOGENOM" id="CLU_3372785_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="34" mass="3740" checksum="AD636A8452509F0F" modified="2009-10-13" version="1">MTRTRRPRTSPASSAEAAAAAREALQQALDRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEH4</accession>
    <name>C7QEH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786158.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1945"/>
    <dbReference type="EnsemblBacteria" id="ACU70865">
        <property type="protein sequence ID" value="ACU70865"/>
        <property type="gene ID" value="Caci_1945"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1945"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1358050_0_0_11"/>
    <dbReference type="OMA" id="WFFARPE"/>
    <dbReference type="OrthoDB" id="1455817at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="22069" checksum="DDF3BFB1D54F5E3F" modified="2009-10-13" version="1">MATEPSDYVKHLPIGEQIPFDADGIPGWEIFPFEGDLRVKKLEPPVLPEPARNGAPGGTPCQPCSWQDSDYIWTDEHWRLRTFPEASIPALVMLEPREHCDLADLPAERAAELGALFQRVERAILTLGGIARVHVARYGDGGDHLHWWFSARPEGMLQMRGSCLLIWEDVLPKVEAERWAATNRTIAAAMAADGGSAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF31</accession>
    <name>C7QF31_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5931</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5931"/>
    <dbReference type="EnsemblBacteria" id="ACU74789">
        <property type="protein sequence ID" value="ACU74789"/>
        <property type="gene ID" value="Caci_5931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5931"/>
    <dbReference type="eggNOG" id="COG1279">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087840_0_0_11"/>
    <dbReference type="OMA" id="FARPRAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="23427" checksum="0F148A25C6B54DE1" modified="2009-10-13" version="1" precursor="true">MISNDSQEKLAGLRITGLPSIVPMTSSLAAAAAGLGTGLSLIIAIGAQNAYVLRQGVRREHVGIIVTICAASDAVLIAAGVGGLGALVRSMPTAVTAIAWIGAAFLVTYGLLAARRAWKHQDHLAADGTGETTLRTAVLTCLALTWLNPHVYLDTVLLLGTVGNSYGNAHWSFALGATTASILWFTTLGFGAGRLGKLLARPKAWRVLDGVIAITMITLGVAMAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFG5</accession>
    <name>C7QFG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7919</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796467.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7919"/>
    <dbReference type="EnsemblBacteria" id="ACU76742">
        <property type="protein sequence ID" value="ACU76742"/>
        <property type="gene ID" value="Caci_7919"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7919"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_3_0_11"/>
    <dbReference type="OMA" id="CNSWSLE"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="27906" checksum="79229C6D86E439B7" modified="2009-10-13" version="1">MLAAQRQAWILQEVRQHGAVRVTELVAALNVSDMTVRRDLDSLADQGLITKVHGGATARGGGSTDEPAFSVKAARQRRAKEAIARAASELVRPGTAIGVSAGSTTYAFAQQLARVPDLTVVTNSPPVAELLHALPGPPQTVILTGGVRTISDALVGPVAIDAIRRLHLDCVFIGVHGIDAEAGFTSPNLMEAETNRMLVSTAQRLVVMADHTKWGVVGLSEIAALHEASVLVSDDGLGSGARQVLREAVGELIVVPVEGAGANEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFJ9</accession>
    <name>C7QFJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796501.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7953"/>
    <dbReference type="EnsemblBacteria" id="ACU76776">
        <property type="protein sequence ID" value="ACU76776"/>
        <property type="gene ID" value="Caci_7953"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7953"/>
    <dbReference type="HOGENOM" id="CLU_1131998_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983181" evidence="1">
        <location>
            <begin position="32"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="23222" checksum="807DAF79885F7440" modified="2009-10-13" version="1" precursor="true">MSTLSTTVRRGLVVTAAAMAAGPVVGGVASAATAPTTSVPLDTAPISTTAATPALQAVAPLPVTRSALPIGGLDSVMPISGGLANGLPVNGLTGGLPLNNIAGGLPVSGLAGQLPVVGPMAQNLPVVGQMTGAPAPTAPSAAAAGEQAASELKAAFPAPHMPTPPALMTPAHAAGKRSRAVAPVAPAVTAPTITAPTVTSSPAASAKPQSSLPVVGQLPTSNLPVVGSLTQGLPVGSLTGILGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFK4</accession>
    <name>C7QFK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7958"/>
    <dbReference type="EnsemblBacteria" id="ACU76781">
        <property type="protein sequence ID" value="ACU76781"/>
        <property type="gene ID" value="Caci_7958"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7958"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="WLRWQRT"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="57"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="155"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="38052" checksum="DE926520CC46F7C8" modified="2009-10-13" version="1">MSDAGQVAELDGARGALVGVRIDGGADFGGDVGDVKEGVGERVGDGADGLEEAVAVFTRVRPRLFGIAYRILSSVTEAEDLVQEVWVRWQTCDRKAVRDPAAFLATTAIRLAINELRSARVRREKYVGPWLPEPVETSADPYLGAERGEALQFAALLLMEKLTPNERAAYVLREAFDYSYPEIADVLGTTGAAVRQSVSRARKHMARERRVSAPAAAQRELLTKFIAAARDGDMAALEQLFAADVASVSDGNGRARVGRRPVVGASRVAKFLKAMSSWFWDGVEVLWVTTNGQTSALLRHDGALWGMITVSVSGEHIDQVLWMFNPEKITARSLPPGLVLDGGFAEVTKASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL3</accession>
    <name>C7QFL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoesterase HXTX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796515.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7967"/>
    <dbReference type="EnsemblBacteria" id="ACU76790">
        <property type="protein sequence ID" value="ACU76790"/>
        <property type="gene ID" value="Caci_7967"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7967"/>
    <dbReference type="eggNOG" id="COG1514">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104553_0_0_11"/>
    <dbReference type="OMA" id="RELQFPY"/>
    <dbReference type="OrthoDB" id="1696971at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21031" checksum="0F0FE5166DE70487" modified="2009-10-13" version="1">MGGVSDPLAATFAGANPFAAGTRGADTVTIGVAVPVPEPYGTELQKWRESFHDPMALAIPTHVTLLPPSEVEREDLPGIEDHLAKAASSGRPFSMLLKGTGTFRPISPVTFVRVAQGAEECAATEALVRSGILAGEARFPYHPHVTVAHELPEESLSRAQEALAGYEARFPITGFALYLHGDDGVWRVRRLFPYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFM8</accession>
    <name>C7QFM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784262.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0012"/>
    <dbReference type="EnsemblBacteria" id="ACU68967">
        <property type="protein sequence ID" value="ACU68967"/>
        <property type="gene ID" value="Caci_0012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0012"/>
    <dbReference type="HOGENOM" id="CLU_2768233_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU68967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7658" checksum="A5E777CA2156F7B4" modified="2009-10-13" version="1">MPRFEFKYASDLVVGDWAQIGGKWVEVLGCATDPSGWTRLILDRSPLPETVVHQTVDMPWSPMRPAGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFV2</accession>
    <name>C7QFV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, PaaX family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2009"/>
    <dbReference type="EnsemblBacteria" id="ACU70929">
        <property type="protein sequence ID" value="ACU70929"/>
        <property type="gene ID" value="Caci_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2009"/>
    <dbReference type="eggNOG" id="COG3327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067515_2_0_11"/>
    <dbReference type="OMA" id="WITTERV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012906">
        <property type="entry name" value="PaaX-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013225">
        <property type="entry name" value="PaaX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011965">
        <property type="entry name" value="PaaX_trns_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07848">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08223">
        <property type="entry name" value="PaaX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020623">
        <property type="entry name" value="PaaX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PaaX" evidence="1">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PaaX_C" evidence="2">
        <location>
            <begin position="188"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="31815" checksum="B97EDC1B16661126" modified="2009-10-13" version="1">MEGSEASPRVTRRRETTTFSARSLLMTLLGEYVLPHERPTWTSTIIEALSADGVEEKAARQALARTSAEGWITTERVSRRVRWSLTPEGRQLLTEGAERIFSFGRTTPAWDGRWLMLLVTVPETRRDLRHRLRTRLTWAGFGTADPGVWINPDPAREDEAREVLRDLDLDQGAMSFTAAHGSIGSLAAMVARAWDLSTLEAEYEAFVSAFGALTPDTDAATLRTQTRLVHEWRRFPFLDPRLPRELLPADWTGAKAVEVFHARHAEWHEKAQREWAALNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFY5</accession>
    <name>C7QFY5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 9">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_2042</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2042"/>
    <dbReference type="EnsemblBacteria" id="ACU70962">
        <property type="protein sequence ID" value="ACU70962"/>
        <property type="gene ID" value="Caci_2042"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2042"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_3_0_11"/>
    <dbReference type="OMA" id="RGSIQNI"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="649"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="841" mass="90579" checksum="63D7C3C0F25359A8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG82</accession>
    <name>C7QG82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792656.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4062"/>
    <dbReference type="EnsemblBacteria" id="ACU72927">
        <property type="protein sequence ID" value="ACU72927"/>
        <property type="gene ID" value="Caci_4062"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4062"/>
    <dbReference type="HOGENOM" id="CLU_1934252_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14383" checksum="7A7DF2CDB62EF0C5" modified="2009-10-13" version="1">MPTTPAPASVYHPTVDRILIRHLKTPAALARLRDDAEAPETDLLSRLLHLAALRLAERDLQLTRTIRHTQTDLEAAATQLADGRCAEQVLTGRGDQLAILAHRHRDALDHLEPLARLWATGRTDTGEPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGH3</accession>
    <name>C7QGH3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794582.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5995"/>
    <dbReference type="EnsemblBacteria" id="ACU74853">
        <property type="protein sequence ID" value="ACU74853"/>
        <property type="gene ID" value="Caci_5995"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5995"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_0_11"/>
    <dbReference type="OMA" id="AWTVCWL"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Reductase_C" evidence="2">
        <location>
            <begin position="304"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="41647" checksum="CF99ECEA5AF28DD4" modified="2009-10-13" version="1">MKLERVLVVGGGMAGLHTVRSLREKGFQGAVTFLGEERHAPYDRPPLSKAVLAGSARGAVEKVDELAFAFDFAEAEVQCRFGERAVGWAPGVVTTGTGVELRYDRLVVATGSVPIQLGFGETLRTYEDSVRLRERINGGKPMAIVGAGWIGAEVATAARNAGTGVVVHEARDRPLAAIFPPAVGQAMTAWYAEAGVELKCSDPVTGPPPGVDHTLVAVGARPDTRWLGEAFHRAQDGSLLVSEYLETNVPGVFAVGDVAAYRSVRYGGRHIRVEHWDNALRGPQALVPNVLEGVGAELHDPVPYFWSEQFGRMVQYVGHHTSADRMVLRGDLSTPTWSVCWLDPHARLTAVLAVGRPRDLAQGRRLVTAGAVLDAARVADAGAALTTAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGP9</accession>
    <name>C7QGP9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794658.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74929">
        <property type="protein sequence ID" value="ACU74929"/>
        <property type="gene ID" value="Caci_6073"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6073"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="MAFGRWI"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="36090" checksum="D74411135257D4CC" modified="2009-10-13" version="1">MRHVRLGRSGLKVSRLCLGMMSYGSPESRAWIMPEDAALPLVARAVEAGITYFDTADMYSKGASEEVTGRILPKLFAHRDDYVLATKVFFPTGTAPNDSGLSRKHIMASIDASLRRLGTDYVDLYQIHRWDTETPIEETMEALHDVVRSGKARYIGASSMAAWQFSKAQYTADLHGWTRFVSMQNHYNLVYREEEREMIPLCLDQGIGVLPWSPLARGLLAGARSRDGGATTTRSTSDPFASELYDARDYPVVDAVEAIAAARGVPPAQISLAWLLSRPAVTAPIFGATKPHHIDDAVAAAELELTAEELAAMETPYRPRGLAVPDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGW4</accession>
    <name>C7QGW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase associated with various cellular activities AAA_5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796539.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7991"/>
    <dbReference type="EnsemblBacteria" id="ACU76814">
        <property type="protein sequence ID" value="ACU76814"/>
        <property type="gene ID" value="Caci_7991"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7991"/>
    <dbReference type="eggNOG" id="COG0714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065561_0_0_11"/>
    <dbReference type="OMA" id="AIRYGWN"/>
    <dbReference type="OrthoDB" id="489714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="1">
        <location>
            <begin position="82"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="364" mass="38982" checksum="891A0F2F95F7FE73" modified="2009-10-13" version="1">MSETVLRQHAEHAFAGELEALRKADADSGRPKPPRWKLSPWAVATYLLGGTLPDGTAITAKYIGPRRIVEIAIATLATDRALLLVGVPGTAKTWVSEHLAAAVSGDSTLLVQGTAGTPEEAMRYGWNYAQLLAHGPSREALVPSPMMRAMATGAIARVEELTRIPADVQDTLITILSEKTLPIPELGEETQAEKGFSVIATANDRDKGVNDLSSALRRRFNTVVLPLPATAEEEIEIVSQRVKSLGRALELPEVPAAHEEIRRVVTVFRELRGGLTEDGKTKLKTPSGTLSPAEAISVVAGGIALAAHFGDGTLRPADVAAGILGAVVKDTSTDKLVWQEYLETVARGRDGWTDFYRSCREVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH04</accession>
    <name>C7QH04_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine N-alpha-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.44</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Histidine trimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">egtD</name>
        <name evidence="5" type="ordered locus">Caci_8031</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidine + 3 S-adenosyl-L-methionine = 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:38471"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15781"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. EgtD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.44" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796579.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8031"/>
    <dbReference type="EnsemblBacteria" id="ACU76854">
        <property type="protein sequence ID" value="ACU76854"/>
        <property type="gene ID" value="Caci_8031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8031"/>
    <dbReference type="eggNOG" id="COG4301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049766_1_0_11"/>
    <dbReference type="OMA" id="RVEMHLV"/>
    <dbReference type="OrthoDB" id="775492at2"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030745">
        <property type="term" value="F:dimethylhistidine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02037">
        <property type="entry name" value="EgtD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035094">
        <property type="entry name" value="EgtD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032888">
        <property type="entry name" value="EgtD_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03438">
        <property type="entry name" value="egtD_ergothio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="4">
        <location>
            <begin position="19"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-histidine binding" evidence="3">
        <location>
            <begin position="283"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="36184" checksum="EE9A447AE33C0822" modified="2009-10-13" version="1">MSGIEIERRLPEDFFAAALRDDVLKGLTAEPKWLPPKWFYDARGSELFEEITRLPEYYPTRAEREILATRAAEIAAVTRAETLAELGSGSSTKTTLLLDALRDAGTLRRYDPIDVSEAALLASGEQLQKRYPELTIHAVVTDFEERLAIPESAGARLVVFLGGTIGNLLPEERSVFLARLRAGLRPGEWLLLGTDLVKDPETLVAAYDDAAGVTAEFNKNVLTVVDRELDADFDPDDFDHVALWDPAAEWIEMRLRARRDLSVRLKELDLGVSFERGEELRTEISAKFRREGVARELDAAGFAVRHWWTDEQARFGLSLAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHL2</accession>
    <name>C7QHL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786330.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2118"/>
    <dbReference type="EnsemblBacteria" id="ACU71037">
        <property type="protein sequence ID" value="ACU71037"/>
        <property type="gene ID" value="Caci_2118"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2118"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034827_0_0_11"/>
    <dbReference type="OMA" id="LFNPMTK"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="3">
        <location>
            <begin position="249"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="577" mass="64196" checksum="072DD48FE069F5BA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW1</accession>
    <name>C7QHW1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation and cell division protein SsgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2217</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell septum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SsgA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786429.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2217"/>
    <dbReference type="EnsemblBacteria" id="ACU71136">
        <property type="protein sequence ID" value="ACU71136"/>
        <property type="gene ID" value="Caci_2217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2217"/>
    <dbReference type="eggNOG" id="ENOG5032RFA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126599_0_1_11"/>
    <dbReference type="OMA" id="NDEPVEW"/>
    <dbReference type="OrthoDB" id="1627707at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006776">
        <property type="entry name" value="SsgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038658">
        <property type="entry name" value="SsgB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04686">
        <property type="entry name" value="SsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14891" checksum="263E90702A9D17F3" modified="2009-10-13" version="1">MSSSVTCELQLRLVISGDSSLPVPAGLRYDTADPYAVHATFHTGGQDTVDWVFARELLAEGLRRPTGTGDVRVWPSRSRGQAIVCLALSSPEGEALLEAPARALESFLKRTNTAVPPGLEHRFYDLDAELVHLFADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI35</accession>
    <name>C7QI35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792809.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4216"/>
    <dbReference type="EnsemblBacteria" id="ACU73080">
        <property type="protein sequence ID" value="ACU73080"/>
        <property type="gene ID" value="Caci_4216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4216"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_5_2_11"/>
    <dbReference type="OMA" id="VMVHQPV"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="34240" checksum="B9E484BEAA9B2285" modified="2009-10-13" version="1">MTTAPDDVTASEEVTASSLADLRARLATVVAIPVTPFTPDGDVDWGGHATVIRRLVDDGVQAVTPNGNTGEFYTLSEPEKRRAVESTVEAVDGRAEVVAGVGLDMASAVDAAQHAARVGASALMIHQPVHPYRSAEGWIEYHRVIADAVPRLGVILYVRDERVAGEHIATLARRSPNVIGVKYAVPDPVRFASVARDAGLETFAWIAGLAELSAPGYWAVGASGFTSGLVNVAPRLSAAMLDALRGGDFAKSMLLWETVREFEELRAADASADNVSVVKEALAQLGFIDRDVRPPSRTLPQALRDRITVVLEQWRVGGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI37</accession>
    <name>C7QI37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine/putrescine transport system substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4218"/>
    <dbReference type="EnsemblBacteria" id="ACU73082">
        <property type="protein sequence ID" value="ACU73082"/>
        <property type="gene ID" value="Caci_4218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4218"/>
    <dbReference type="eggNOG" id="COG4134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_722939_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982899" evidence="1">
        <location>
            <begin position="45"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="43247" checksum="773798BB54AAC8D8" modified="2009-10-13" version="1" precursor="true">MSAMSVRKDAMSRRTLLGSLAVGAAAAPLVSACGAPGSSGAAKAAPPSTLASTPSKPVSLNILDVAGNLQLTQPILDAFKAQHPQIVSGITTSTGTAPELAPKVQAQQQGGNVQIDLVLTGTDGLAAGIEKQLWYNLKPYYDTFFPGLMANYNPAAASMASLAQDQGIELVVTPSGPLLEYDPAKVATPPTTPDALLAWAQAHPGKFQYAQPRNSGPGRTFLMGLPYLLGDSDPSDPTNGWAKTWDYLAQLGKYAASYPTKTSATMTAIAQGTAWMIASTAGWYINPRATGTVPAGIKVVKFDNLTWVSDAQFGVIPKGIPADHLTAVLRLLAFALTPEQQAVTYDQGYFYPGPAVKGVTLAQAPAASQQVVQKFGDPDFDTWTSSGPIRNSLPAQAQVTAFDLWDKKIGAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL4</accession>
    <name>C7QIL4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794820.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6237"/>
    <dbReference type="EnsemblBacteria" id="ACU75091">
        <property type="protein sequence ID" value="ACU75091"/>
        <property type="gene ID" value="Caci_6237"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6237"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_11_11"/>
    <dbReference type="OMA" id="YWLYFVT"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="9"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="505" mass="55469" checksum="61332A5F039A9F11" modified="2009-10-13" version="1">MKPSALVTGATGYIGGRLVPELLDAGFDVRCMARDPDRLRDHAWAERVERVRGDVLSPETLPPALEGIDVAYYLIHSLTTGAGFEQTEEKAARSFASAARDAGVSRIVYLGGMAPEETPVTELSPHLRSRVRVGQALRSSGIPTVELRAAVVIGSGSASFEMLRYLTERLPVMVTPRWVGTRIQPIAVRDVLRYLVGSASAPDDVVGAGGVFDIGGRDVLTYREMMLRYAQVAGLPRRWILPVPVLTPGLSSHWVGAVTPVPASIARPLVESLRHEVVCADHRVAELVPDPPQGLIGFDEAVRLARTRVQEANVTTRWSSASVLGAPSDPLPTDPDWAGGSLYRDVREAEVDIAPERVWRAVEAIGGQTGWYSFPLAWAVRGWLDRMVGGIGLRRGRRDPNTLRLGDTLDFWRVEALERGHLLRLRAEMKLPGLAWLEMRVEPTETGRTRYRQRALFYPHGLFGHLYWWSVAPFHAVVFGGMVRNLLRRAAEESSATSTTSATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ9</accession>
    <name>C7QIQ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8136</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796684.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8136"/>
    <dbReference type="EnsemblBacteria" id="ACU76959">
        <property type="protein sequence ID" value="ACU76959"/>
        <property type="gene ID" value="Caci_8136"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8136"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_1_0_11"/>
    <dbReference type="OMA" id="VFPFEWG"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="724"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="779"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="821"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="17"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="301"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="502"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="756"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="855" mass="88317" checksum="12319AEBAE079E00" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIU0</accession>
    <name>C7QIU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8167"/>
    <dbReference type="EnsemblBacteria" id="ACU76990">
        <property type="protein sequence ID" value="ACU76990"/>
        <property type="gene ID" value="Caci_8167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8167"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_2_3_11"/>
    <dbReference type="OMA" id="YWTLGIE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="3">
        <location>
            <begin position="28"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="45849" checksum="A8E7A592AD520A62" modified="2009-10-13" version="1">MSSDTVAVAKAVPIPVVEAPKAPRNRMAALDGMRFIAASAVLAYHYLGDTEGIWGRDAGKIFPSEHHATSYGFLGVEFFFLISGFVICMSSWGKGLGSFFASRVSRLYPAYWAAVTLTTLIFVWNPAAGSPLRLDDYFSNMTMLHFSFGVASASGVYWTLWLELRFYLLFALVVWRGVTYRRVVAFCLLWTAASVLVPSFNSPILHGIIQEDYSPYFIGGITMYLMHRYRPNPLLWLMLGTQWVLAQHQVAARVVEGSRLTGAHLSWNGGVILVTVFFLAVLAVALGWLDWANWRWLTVLGTLTYPLYLVHSAVGQEIIKVWYRKAHHPNAWVILAVATAASLAVAWLIQRFIEKPFGPRLRKAVQRSLKEINLPEPALRAAKAAKSGTSAGTSVATPADVVEVLSPPAPRGATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX4</accession>
    <name>C7QIX4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796749.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8201"/>
    <dbReference type="EnsemblBacteria" id="ACU77024">
        <property type="protein sequence ID" value="ACU77024"/>
        <property type="gene ID" value="Caci_8201"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8201"/>
    <dbReference type="eggNOG" id="ENOG50330CI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078491_0_0_11"/>
    <dbReference type="OrthoDB" id="1762247at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="23525" checksum="2E6085636AFFCEC3" modified="2009-10-13" version="1" precursor="true">MSKDRTIPGAPPAGAVFGGGRAVAASRLPSAPRERKPALAALAVLLILAGALATMLLVTQSGHRVSVVRVGGATIAAESTLTAGEFVETSVAQDNDIKYIPWDQVGSLNKRVTYNTLVKGSLLTSDMLTDQSAVPTGVAPGSTLMGVQIKQGHYPTGQMYAGDKFTLYAQTTTPGPNGQGTTTAWAELGTVTLVTRDNAETLTATVAVPSDKVLAIANASDLMLTKTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK01</accession>
    <name>C7QK01_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4375"/>
    <dbReference type="EnsemblBacteria" id="ACU73239">
        <property type="protein sequence ID" value="ACU73239"/>
        <property type="gene ID" value="Caci_4375"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4375"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091304_2_0_11"/>
    <dbReference type="OMA" id="DWCGPCA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="15029" checksum="ADFFB9A5A7167468" modified="2009-10-13" version="1" precursor="true">MDLAGVAAAVGALAAASAFGLWRKRSDGTVRDESATAERLSAADLGIDLDPRATLVQFSSKVCRYCGPTRRVLTELADQHTVAYLDIDAEEHLDLARRLTVLRTPTVLLLDGTGRITHRVSGPPRRAELAAAVSALASLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKD4</accession>
    <name>C7QKD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794937.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75208">
        <property type="protein sequence ID" value="ACU75208"/>
        <property type="gene ID" value="Caci_6354"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6354"/>
    <dbReference type="HOGENOM" id="CLU_2823187_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="66" mass="6492" checksum="F86A2C4840B2D5E3" modified="2009-10-13" version="1" precursor="true">MATTSAWLTPHHGRRIVRLIGMPAGLLIARYGAAAAAVPGGGSVAGRGAVPSTAQTAVSGRGMPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVG2</accession>
    <name>C7PVG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784613.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0365"/>
    <dbReference type="EnsemblBacteria" id="ACU69318">
        <property type="protein sequence ID" value="ACU69318"/>
        <property type="gene ID" value="Caci_0365"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0365"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074078_3_0_11"/>
    <dbReference type="OMA" id="DCGALTT"/>
    <dbReference type="OrthoDB" id="1635544at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007995">
        <property type="entry name" value="DUF742"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36221">
        <property type="entry name" value="PTHR36221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05331">
        <property type="entry name" value="DUF742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="13139" checksum="1928945C5080AEAA" modified="2009-10-13" version="1">MSRGDPDAFVDSAAGRLIRPYAVAGGRTAPNADFHLVTYVVATGRALSDLGPDHDDILSLCDRPISVAEVSALSGLPLAVTKILLSDLLGWRAIDTRAPVPVFERARPSTDLLEKVLDALYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT5</accession>
    <name>C7PVT5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786620.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2409"/>
    <dbReference type="EnsemblBacteria" id="ACU71327">
        <property type="protein sequence ID" value="ACU71327"/>
        <property type="gene ID" value="Caci_2409"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2409"/>
    <dbReference type="eggNOG" id="COG3801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138549_2_0_11"/>
    <dbReference type="OMA" id="WCAAPPG"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13764" checksum="330896E91D002AA0" modified="2009-10-13" version="1">MTPEETAVLDRLRAVCLALPEVEERESHGEPTWFIRGKRTLAMFSSHHHGKRLGFWCPAPEGVQELRMEQDPDVFYRPPYVGVHGWLGVNLDAGPDWEDVEEIVRDAYLKVAPKTLAARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW85</accession>
    <name>C7PW85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase small</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793062.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4470"/>
    <dbReference type="EnsemblBacteria" id="ACU73333">
        <property type="protein sequence ID" value="ACU73333"/>
        <property type="gene ID" value="Caci_4470"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4470"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100602_0_0_11"/>
    <dbReference type="OMA" id="RWHERAY"/>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="31"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24162" checksum="EF1C1DFE43065E79" modified="2009-10-13" version="1">MTADATLSDCHGGFEDRSGQFDLLGRSWTLLPGVFAPVHTTSTALFSSWLPFPPGGAFLEIGSGAGVTAVTAALAGCAHVTAVDISPAAVANTAANARRHGVADRVRVLNSDLFEALDTGERYDAIYWNSNVIDAPPEFEYLEELRWAFFDRGYATHHRFLTQGPDLLRPGGRMFLGFNTLGNKERLRVMADELGLELATFRRRPGVLGGIRVELSLLEVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX48</accession>
    <name>C7PX48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monosaccharide ABC transporter substrate-binding protein, CUT2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784694.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0447"/>
    <dbReference type="EnsemblBacteria" id="ACU69399">
        <property type="protein sequence ID" value="ACU69399"/>
        <property type="gene ID" value="Caci_0447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0447"/>
    <dbReference type="eggNOG" id="COG4213">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_13_3_11"/>
    <dbReference type="OMA" id="YTDGWLP"/>
    <dbReference type="OrthoDB" id="859573at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982567" evidence="1">
        <location>
            <begin position="31"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="38"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="360" mass="36910" checksum="E11EAB9630F36FE3" modified="2009-10-13" version="1" precursor="true">MRHSIIRSLAVGAVAALALGACSSGTGGSAKGRKPYIGVILPDTTSSARWATQDQPALAAAFKAKNVKYDIQNAQGNKTQFQAIADHMLKEGVNILMIVDLDAATGTAVLAKARQQGVPTIDYDRLTLGGGADYYVSFDNVDVGELQGQGLVACLGGTKKPVVAEVNGSPTDNNATLFAQGYNSVLNPLYADGTFIKGPNQSTTDWKNDIAGQNFAKMLAEAPNIGGVLVANDGMAQAVIGVLKQHHLNGRVQVTGQDATVAGLQSVLVGDQCMTIFKDSVKEANAAAELATALATGGSASSANTMVADSVTGKLVASVMLTPEAIVKQNVGDVISAGAVTKAQVCTPEFAEACTANGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXK9</accession>
    <name>C7PXK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786755.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2544"/>
    <dbReference type="EnsemblBacteria" id="ACU71462">
        <property type="protein sequence ID" value="ACU71462"/>
        <property type="gene ID" value="Caci_2544"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2544"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009095_0_0_11"/>
    <dbReference type="OMA" id="NAVITHE"/>
    <dbReference type="OrthoDB" id="956322at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="944" mass="102697" checksum="6AE17174A1B3BFCC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU2</accession>
    <name>C7PXU2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793131.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4539"/>
    <dbReference type="EnsemblBacteria" id="ACU73402">
        <property type="protein sequence ID" value="ACU73402"/>
        <property type="gene ID" value="Caci_4539"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4539"/>
    <dbReference type="eggNOG" id="ENOG5032UMU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139647_0_0_11"/>
    <dbReference type="OMA" id="RQMRWAN"/>
    <dbReference type="OrthoDB" id="1582839at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18971" checksum="4354B32668C7AF2D" modified="2009-10-13" version="1">MKAVAELVDELHQGENDMVGRLQRTAHQHAADYDVRHGATHLSEWSKDHVSRLAEAGRRFGLELSSTTDVDGESVVQQTLDKTAKALRHRPEPALLLLRDLRELHLCAAGNNLGWTMLAQAAKALRDKELVQLTDDCQPQTVRQMRWTETLIKELSPQALASMSSESGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY45</accession>
    <name>C7PY45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793234.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73505">
        <property type="protein sequence ID" value="ACU73505"/>
        <property type="gene ID" value="Caci_4644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4644"/>
    <dbReference type="HOGENOM" id="CLU_1792991_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982672" evidence="1">
        <location>
            <begin position="23"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15156" checksum="6B5886549830EACA" modified="2009-10-13" version="1" precursor="true">MTLPAGKLTALLLAVGCLAACGDSGNYRTYHGDVGTNDVQGTWTAGCGGTIELKPGGGASLTNVPSYNEQEKFTDANVLYSGDARWTISEGSGWKSDTNPPTLDLVIRNFSSPLQFATVKGKLSLALDIGPLDKDTYCKYSRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYA2</accession>
    <name>C7PYA2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6544</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795121.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6544"/>
    <dbReference type="EnsemblBacteria" id="ACU75392">
        <property type="protein sequence ID" value="ACU75392"/>
        <property type="gene ID" value="Caci_6544"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6544"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_2_11"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="16"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11609" checksum="1789AD404F56B4D7" modified="2009-10-13" version="1">MPEFIYRVRHQGTGSVVEVSGDIDMSVHQQLTEALEPLVAAGDVVLDCSQVSFMDSMGLRVALSMVRQAEEVGTTFALVPSKAVSRVLELAGVTEIFDIRDTVPSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC2</accession>
    <name>C7PYC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6566"/>
    <dbReference type="EnsemblBacteria" id="ACU75412">
        <property type="protein sequence ID" value="ACU75412"/>
        <property type="gene ID" value="Caci_6566"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6566"/>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294364_0_0_11"/>
    <dbReference type="OMA" id="LGAWWPA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="803"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="849"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="901"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="940" mass="95110" checksum="D161C9B7A7077964" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYQ5</accession>
    <name>C7PYQ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8557"/>
    <dbReference type="EnsemblBacteria" id="ACU77377">
        <property type="protein sequence ID" value="ACU77377"/>
        <property type="gene ID" value="Caci_8557"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8557"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034934_1_1_11"/>
    <dbReference type="OMA" id="YLLWWAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="3">
        <location>
            <begin position="240"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="255"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="499" mass="55228" checksum="763356B208533014" modified="2009-10-13" version="1">MFRTVHGDASSADKATRKVGGVYVREPVFEVPVWWLAIRRFFGFFGLAGRKAAKHPVLSSLIALAAWLRIALGSSAFGWLLVGVLLTLSAWAVLHWASFERMVRFPVVSAWRRWFVYERRWHATMAVCGLAVLYGDLEYVPSLRQVRSTRFVDRVIVDMVSGQIPEQWENQAPALAHTFGALSCRVRTVKPRRIALEFMHADPLAATVKPGQLDTDDESHSVDRMPVNLAALPLGVCADGQPWTLRLTTHVLIAGASEAGKGSVVWALLRALGPAIRTGYVAPWVLDPKGGMELSFGEPLFQRFEADSYEGMARMLEDAADLMDRRTRLLRGVARQHIPTPDEPLVLVVVDEMADLTSYCPDRAIRQRIASALSRLLSKGRAAAVHVVAALQDPRKDVLPFRDLFPVRICLRVTEASHVDMVLGDGARDRGATCDLIDPELAGVGFVTVAGVREPVRVRATYHSDSDIAAMVERFKPLIHDAIPAQRSHDLDGKEVDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYR4</accession>
    <name>C7PYR4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="6 15">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Caci_8567</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="6 15"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797111.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8567"/>
    <dbReference type="EnsemblBacteria" id="ACU77386">
        <property type="protein sequence ID" value="ACU77386"/>
        <property type="gene ID" value="Caci_8567"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8567"/>
    <dbReference type="eggNOG" id="COG1282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007866_4_0_11"/>
    <dbReference type="OMA" id="KRGMSAG"/>
    <dbReference type="OrthoDB" id="788546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="11 15" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-1278">Translocase</keyword>
    <keyword evidence="10 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="17">
        <location>
            <begin position="8"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACU77386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="47055" checksum="9D58F3F58952E837" modified="2009-10-13" version="1">MSSAWRDTAYLISGVCFILTLKGLSAPRTARMGTVIGSCGAALAVLVSLTTPHLKHLGLIIGAIVVGTAIGLPTARKVRMTAMPQLVALFNGVGGGAAALVAAVEFLRPGKGIEHAASADLAATAFTILVGGVSFSGSMITYAKLQELMTTRPVVLPAGRWVTIGVAAASVLFGILLVPWPSTALMVLLALLALAFGVLFVLPVGGADVPIVISLLNAFTGLTVAASGYVLSNTLLVIAGTLVGASGTLLTRMMAAAMGRPLTGTLFGAFTATAGGAAVSGDGAARPVRTSSPEDVAILLGYARKVVIVPGYGLAVAQAQHTVREVADLLASRGVQVSYGIHPVAGRMPGHMNVLLAEANVPYESLLELDAANSELASADVAVVIGANDVVNPAARQPTGSPISGMPILDVDLAQQVVFCKRSMRPGFAGVENELLYAQNTSLLFGDAKESMAKVLAALKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYS4</accession>
    <name>C7PYS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8577"/>
    <dbReference type="EnsemblBacteria" id="ACU77396">
        <property type="protein sequence ID" value="ACU77396"/>
        <property type="gene ID" value="Caci_8577"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8577"/>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037208_0_0_11"/>
    <dbReference type="OMA" id="LSHAIMG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="481" mass="51032" checksum="9E11B52F3570A173" modified="2009-10-13" version="1">MTPSPTLGPASSKSADPSWWDIPGQIEKAIDTWLGDLVKSALKPVLPFVATSLLSSPNLSSGRIASIWTSVLILSNTLYVLFILAGGILVMTHGTLQTRHELKEIAPRLVIGMVASNASLWLICQSVSLGNALVAALMNGNLSSEGIGSRLTSLIVYNVFLPDGVGEVFLVIIGGAIAVLGVALVVTDLVRATVLMVLTAGAPLALACLAHPQTEGLAKLWWRAILGCLATQVLQALVLIICLQVFFDPQADNVLGLPTRGGLTDLLICLVLFFMLIKIPIWTSRVVLQRGALGQTRITGLARSYLQYRAFGAIPSRFDVGRRRSRPGGGTGPLPPPPTSPGGPGRGPRPCTGPGHGKFGPLPILHGGPRGPSFSSRPRATEPREATVTPRPAEEPTRSPRAQPTPPRPLITPAKRPISHTTRSPNPPQSKTPPVRDRPTQAVPQPPSPSPVAKHLAPPTPPRAPRPTNSHKPKLRPLSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ47</accession>
    <name>C7PZ47_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0667</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0667"/>
    <dbReference type="EnsemblBacteria" id="ACU69603">
        <property type="protein sequence ID" value="ACU69603"/>
        <property type="gene ID" value="Caci_0667"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0667"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430050_0_0_11"/>
    <dbReference type="OMA" id="KEHAGHN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="285"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="432"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="510"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="550"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="636" mass="65297" checksum="2C2422F8AC1816B4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT9</accession>
    <name>C7PZT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">40-residue YVTN family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793333.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4743"/>
    <dbReference type="EnsemblBacteria" id="ACU73604">
        <property type="protein sequence ID" value="ACU73604"/>
        <property type="gene ID" value="Caci_4743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4743"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009318_2_4_11"/>
    <dbReference type="OMA" id="KVGRFPW"/>
    <dbReference type="OrthoDB" id="892272at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982650" evidence="2">
        <location>
            <begin position="48"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="44314" checksum="45882B2B36658836" modified="2009-10-13" version="1" precursor="true">MTPQPTPHSCEPARPRPARPRRATAALAVGLLTAAALPTLAAGAAHAAGAAAPLPPGTYVYVANAASNSVSVIDTASQTVVATVPVGSAPTGIAASADGHRVYVTDSGSSSVSVIDTQAASGPAVVASIAVGRQPQSAALSPDGTRLYVGDDIAGTVSVIDTASDTVLSTIAAGPGAEGLAVSPDGSRVYAADTGGSSVTVIDAATDTVVTTVPVGQTPVGLTVSPDGSHVYVPDYGSGQVSVIDTATETVSATVAVGANPHSAAVSPDGATVYVTDAGSGTVSVISTATETLSSTFSVGVAPHGIALAVAPTGGSAYIAEYGAASVSAVNLASDAVTATIGVGTNPVYLAVSVIKPLPTALTAGTAQLSLLPLGEANLNAKLTSDGVPVAGQKITFTASDGRVLCTATTNSHGKAVCNTAPGLLESVAVLLTGYTATFAGSTYYLPSCAHGETALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ0</accession>
    <name>C7PZZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795212.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6637"/>
    <dbReference type="EnsemblBacteria" id="ACU75483">
        <property type="protein sequence ID" value="ACU75483"/>
        <property type="gene ID" value="Caci_6637"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6637"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_6_2_11"/>
    <dbReference type="OMA" id="AWDAGHD"/>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004557">
        <property type="entry name" value="PrmC-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00537">
        <property type="entry name" value="hemK_rel_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="2">
        <location>
            <begin position="17"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23238" checksum="250DFF143FB81CBB" modified="2009-10-13" version="1">MTFLFVPPGVYQPRSDTDLLIDALRNERLGRNCRVLDLGTGSGAVAVAAARRGARVTAVDISRRAVATTWVNGVLHRRFIRVRRGDFLEALGPGRFDVVVSNPPYVPSQDLPVKGSARAWDAGPTGRYWLDRICAEAPKVLKRGGVLLLVHSSLADVQGTVQTMSQAGLTVQTVTRVAGGLGPITNSRAGWLEREGLLAVGERMEEMVVIRGVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q030</accession>
    <name>C7Q030_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6677"/>
    <dbReference type="EnsemblBacteria" id="ACU75523">
        <property type="protein sequence ID" value="ACU75523"/>
        <property type="gene ID" value="Caci_6677"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6677"/>
    <dbReference type="eggNOG" id="ENOG502ZUDA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952160_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="292" mass="29246" checksum="BC42C76DF77D255E" modified="2009-10-13" version="1">MTRMTHGPGDAVFPDGERLHDAFAEEVDRPGLEGPSFDAVLRSGTARRRRHRVTTGTTFAVASVAAVATAVLATGGGTSHDVSTAAGSTGTNSTTTSQTSGITTLTSPAAGPAKAAPSLPADVVLTSGTVDGHSWQLVRAYAPDQPPKSSDAHDPANGSAPKWCGYLNVVADGVKTNAGTGDTPCLGPNGKPVTAANPAEPGFTSIAILDAHQGRLGAVVAGSVSPQIASVTAQCGTQSFTTKTSRPAGDATAYYTFTFPAGSSCQVGTLSFFNAAGTPTAFKSNVVLAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q067</accession>
    <name>C7Q067_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6714"/>
    <dbReference type="EnsemblBacteria" id="ACU75560">
        <property type="protein sequence ID" value="ACU75560"/>
        <property type="gene ID" value="Caci_6714"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6714"/>
    <dbReference type="HOGENOM" id="CLU_2506646_0_0_11"/>
    <dbReference type="OrthoDB" id="2098409at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9158" checksum="165145590C9DB5EE" modified="2009-10-13" version="1">MPTAWHTGDVAKKQPGKDPETVTLQVTLPAQVAKDLVALAELYHATPERMVASWTQTYVENLVAGLTPSGAAPETPDSSQPHRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0D3</accession>
    <name>C7Q0D3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF302 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8650"/>
    <dbReference type="EnsemblBacteria" id="ACU77466">
        <property type="protein sequence ID" value="ACU77466"/>
        <property type="gene ID" value="Caci_8650"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8650"/>
    <dbReference type="eggNOG" id="COG3439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116237_3_0_11"/>
    <dbReference type="OMA" id="CPAFPGR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005180">
        <property type="entry name" value="DUF302"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03625">
        <property type="entry name" value="DUF302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="SSF103247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF302" evidence="1">
        <location>
            <begin position="36"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14046" checksum="9C903E5D823F8A2F" modified="2009-10-13" version="1">MNSPVVTKTATTSVTMTARRLLEVLEHAGATVFAVIDQAEAARSAGLELRDTVLILFGNPTAGTPVMDAHPLAALDLPLRILLWDDNGTTRVTYLDPAALTERYGVEPEMLDKLKSIHAVSDALTAAAPPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q101</accession>
    <name>C7Q101_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786969.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2763"/>
    <dbReference type="EnsemblBacteria" id="ACU71676">
        <property type="protein sequence ID" value="ACU71676"/>
        <property type="gene ID" value="Caci_2763"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2763"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_3_11"/>
    <dbReference type="OMA" id="GPGHYVF"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982771" evidence="1">
        <location>
            <begin position="34"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="92"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="53712" checksum="36EED2D673F6B696" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q130</accession>
    <name>C7Q130_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2792</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2792"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH30">
        <property type="family name" value="Glycoside Hydrolase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71705">
        <property type="protein sequence ID" value="ACU71705"/>
        <property type="gene ID" value="Caci_2792"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2792"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022864_1_0_11"/>
    <dbReference type="OrthoDB" id="447059at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="481"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="7">
        <location>
            <begin position="571"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="681" mass="71176" checksum="F5E088E71B9E8CEB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q159</accession>
    <name>C7Q159_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2825"/>
    <dbReference type="EnsemblBacteria" id="ACU71734">
        <property type="protein sequence ID" value="ACU71734"/>
        <property type="gene ID" value="Caci_2825"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2825"/>
    <dbReference type="eggNOG" id="ENOG502ZQA4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1297938_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="23485" checksum="03551A3C001F195C" modified="2009-10-13" version="1">MTSVTITLHIDAKHVSERGGVSWTQAHPVAIDLDTLTPRARALAEAVAQLPGKRKGGGEIMCEHRTKTRRDITPDAESWLPPERLDEPARQAWARWDIYRADSEVPPAEYLEIQARKIPPEWRIVCGHAIGLPDPAPVASSQSAGEDDRLTPRAVVEYLATRHQRHIGPSTWRSYAARGQAPAPVGHVGRESLWSPVDVDAWATGQWHADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D2</accession>
    <name>C7Q1D2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793390.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4800"/>
    <dbReference type="ESTHER" id="catad-c7q1d2">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73661">
        <property type="protein sequence ID" value="ACU73661"/>
        <property type="gene ID" value="Caci_4800"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4800"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_3_11"/>
    <dbReference type="OMA" id="WEHQVAV"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="31012" checksum="BC4F4F17E4795B95" modified="2009-10-13" version="1">MRAYHVTIGAYEFTATEEGPQAGPPVVLLHGFPQTSASWQAASRLLAADGLRTIALDQRGYSPGARPLEVSEYHVNRLVQDVVGLLDALHLPSAHLVGHDWGAIVAWHAAVAHPDRFRTLTAVSVPHLKGFYEVLADPGPEGEDQRRRSEYVQLFRMDDKPEDVLLANSARALHDLFSPLPESAILPHYGALGQRPALTAALNWYRAIDVKQSAALANVRIPTTFVWSTEDVAIGRAVAENCAQCVEGPYRFVELNGVSHWIPDQAPVELARAVVDRVRSVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1W5</accession>
    <name>C7Q1W5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795394.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6825"/>
    <dbReference type="EnsemblBacteria" id="ACU75666">
        <property type="protein sequence ID" value="ACU75666"/>
        <property type="gene ID" value="Caci_6825"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6825"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_0_0_11"/>
    <dbReference type="OMA" id="GSDFPNI"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="22"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="32634" checksum="5FC140DD5B20C720" modified="2009-10-13" version="1">MPDADTAEVRRFWQSLGLPGLIDIHTHFMPHRLLERIQAYFDAAGPLLGRVWPIKYRQDEEERLEILRGFGVLAFTSLAYPHKAGMAESLNAWTADFAARTPDCLHSATFFPEPEAASYVPAAIEAGARVFKAHVQVGGYDPADPLLDPVWGALADAGVPVIAHCGSGPVGTPYTGPEPMARVLAAHPALRLVVAHFGLPEYVEFLDLADRYDGVLFDTTMAFTDFFGQVELSDRDRKRIAECEERILFGSDFPNIPYSYTGALESLARLDFGDDWLRAVCHGNAARIFGVEGPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J1</accession>
    <name>C7Q2J1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glycosyl transferase family 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_0901</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785128.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0901"/>
    <dbReference type="EnsemblBacteria" id="ACU69833">
        <property type="protein sequence ID" value="ACU69833"/>
        <property type="gene ID" value="Caci_0901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0901"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007261_1_0_11"/>
    <dbReference type="OMA" id="GIFHQYY"/>
    <dbReference type="OrthoDB" id="956289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="100"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="608"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="680"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="843" mass="83794" checksum="7CE96BE98EAC74E0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M4</accession>
    <name>C7Q2M4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ordered locus">Caci_0934</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785161.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0934"/>
    <dbReference type="EnsemblBacteria" id="ACU69866">
        <property type="protein sequence ID" value="ACU69866"/>
        <property type="gene ID" value="Caci_0934"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0934"/>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_11"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="125"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="30320" checksum="88499E9138267387" modified="2009-10-13" version="1">MGIRKYKPTTPGRRGSSVADFVEITRSTPEKSLVVPVHSKGGRNSTGRVTVRHQGGGHKRAYRLIDFRRNDKDGVPAKVAHIEYDPNRTARIALLHYADGEKRYILAPKNLGQGDRIENGPGADIKPGNNLPLRNIPTGTTIHAIELRPGGGAKIARSAGASVQLVAKDGPFAQLRMPSGEIRNVDLRCRATVGEVGNAEQSNINWGKAGRMRWKGKRPTVRGVAMNPIDHPHGGGEGKTSGGRHPVSPWGQKEGRTRKPGKASDKYIVRRRKSNKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q335</accession>
    <name>C7Q335_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4911"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73771">
        <property type="protein sequence ID" value="ACU73771"/>
        <property type="gene ID" value="Caci_4911"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4911"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052605_0_0_11"/>
    <dbReference type="OMA" id="NPVEMRI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="352"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="48935" checksum="6B9B6D374C817D4D" modified="2009-10-13" version="1" precursor="true">MRRSLNPFPKSRSEDVRRQRARPGRRPRSGGVALAVLALITALFGAATLSPASASASASASAPAASRVQAAASGNTYQRGPDPTLSSVAASTGPFATAQVSVPAGYGFKGGMIYYPTDTSLGTWGAVAIVPGYTALFANEEAWMGPWLASFGFVVIGVETNSTTDYDTQRGTELLAALNYLTTQSPVRDRVDPTRLGVIGHSMGGGGVVYATEHQPSLKGAVALAPFSPSQSMATDTVPTMVMGGQNDTVVTPSYLAGLYATLPASTQSDFIQIAGADHIYYTHPNPVEMRILIPWLKTFLDEDTRYTQFLCPTLADPSGVSMYQSKCPYVPGGGSTPPPPAGGALHAVGAGKCVDVPNSTTTSGTQVQIYSCNGQANQAFTHNSAGELAVTDAGVTDCLDANGKGTTNGTKVIIYPCNGQPNQQWTINSNGTITGVQSGLCLDVTGASTANGALVELWTCNGGSNQKWTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3J3</accession>
    <name>C7Q3J3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6925"/>
    <dbReference type="EnsemblBacteria" id="ACU75758">
        <property type="protein sequence ID" value="ACU75758"/>
        <property type="gene ID" value="Caci_6925"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6925"/>
    <dbReference type="eggNOG" id="ENOG5032QXB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077101_0_0_11"/>
    <dbReference type="OMA" id="QWCVPSL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="34339" checksum="CC9E0D3FBF38A617" modified="2009-10-13" version="1">MTGPHRPVPVGAGADIRTRQDEIEHLRRLRAYSHMYNSAQMWRRLRAAGTLALALIAPVVAVFVPSSTDTLAAVGAGWLVIGRTVLTRLEQHARGDAVRAHELYDTKLFHLPWNQSLAGSPPSPDDIVRAAERVPDHERYHDWYSIDLTGVAWPGDVLLCQRQSMVWSRSDHRAYGNAVLAAGLGWFTAGLVLAVVKDLSLSDYLIKIFLPCAPAFLDTSELAHEHRQHSIAREQTENDIRELWNTYRLAPDNLPVGETRRIQDSAFQLRRTGPRVPTFYYRLRRSSSQHATVTATAELICPENSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q489</accession>
    <name>C7Q489_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chorismate mutase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1021"/>
    <dbReference type="EnsemblBacteria" id="ACU69949">
        <property type="protein sequence ID" value="ACU69949"/>
        <property type="gene ID" value="Caci_1021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1021"/>
    <dbReference type="eggNOG" id="COG1605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139648_1_0_11"/>
    <dbReference type="OMA" id="HSRENEI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="2">
        <location>
            <begin position="51"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="13463" checksum="D242D8539A7C4F0C" modified="2009-10-13" version="1">MTASATADPTSADSSHPVAPEPASPAAPAAPAPTSSDAPTMPAASSPETGQPTPAGVHSGRSQIDDLDARILALITERISTAADIQTARIADGGRRLDLKRETEIIARYRGALGRPGVTVAMAVLELCRGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B5</accession>
    <name>C7Q4B5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785269.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1049"/>
    <dbReference type="EnsemblBacteria" id="ACU69975">
        <property type="protein sequence ID" value="ACU69975"/>
        <property type="gene ID" value="Caci_1049"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1049"/>
    <dbReference type="eggNOG" id="COG4447">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054572_0_0_11"/>
    <dbReference type="OMA" id="ETWLIGS"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982875" evidence="1">
        <location>
            <begin position="28"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="39532" checksum="4EBF9891DD37D2C1" modified="2009-10-13" version="1" precursor="true">MNSAKRAAVALLSAAAFTATAVGTAQAAGRWQQVPVPTGSGNVLAMTQIDQHTTWGAGFRLITDGDSTTLTPLLLARDDRAGSAWKRVATPADGANSRINALSADGARNVWLVGDNDSATDGSILTEHWDGKAWQTASASVPDGTLSAGFLGVATVGPRDAWAVGWTQRMRGDDSYETGLIEHWNGKAWQQIKLPAAVPDTELFSISATGPRDIWAGGVLTDGTDQPVLLHYDGHTWTRATVPNTGLYGEFNTVVAAAPNNVWAAGRTLVDDKDRGHPLVAHYDGHSWKTVAAPGTGVVNAAAVTPGGVTVVGYDKTTSQSYGEQLDGTGWHSLNLPTVGVDSTPYSLSVNSSTVTVGGVYTPDETSPFQPLILTASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B6</accession>
    <name>C7Q4B6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1050"/>
    <dbReference type="EnsemblBacteria" id="ACU69976">
        <property type="protein sequence ID" value="ACU69976"/>
        <property type="gene ID" value="Caci_1050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1050"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024182_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982515" evidence="1">
        <location>
            <begin position="26"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="675" mass="70025" checksum="5CE99147825D5FF1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4G3</accession>
    <name>C7Q4G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787225.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3023"/>
    <dbReference type="EnsemblBacteria" id="ACU71932">
        <property type="protein sequence ID" value="ACU71932"/>
        <property type="gene ID" value="Caci_3023"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3023"/>
    <dbReference type="HOGENOM" id="CLU_2231746_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="105" mass="11387" checksum="D5A14B635AA1F055" modified="2009-10-13" version="1">MATRNITDLRRELVADSHDLCERSKAYLAAMKHSNSTSADFDAFEGLATAGVYAWTLAAVLRRFVEVHPESAEMLALVIGEVMSSGDDWLEDANDDLDVATGVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4G9</accession>
    <name>C7Q4G9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787231.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3029"/>
    <dbReference type="EnsemblBacteria" id="ACU71938">
        <property type="protein sequence ID" value="ACU71938"/>
        <property type="gene ID" value="Caci_3029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3029"/>
    <dbReference type="HOGENOM" id="CLU_1486519_0_0_11"/>
    <dbReference type="OrthoDB" id="2190444at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="20052" checksum="4ACBDFC131B2D6D1" modified="2009-10-13" version="1">MNPTPDTGQLWCPRRAESVHQSAGPDTWTDYPSITNGIGPCCSYCGSLDPDVFLAKVREGWIVEPTDKPTKAYLDALYTPEEIERIKAGSITWQAVRQLKLDEGGSEDEATAAANAHWGQYEAPIMTGRTVAKLYYQHLTPAQRDEFLKLHNGGAMRISWPGRFYVRPYFSRGGEAVAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4I6</accession>
    <name>C7Q4I6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787248.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3046"/>
    <dbReference type="EnsemblBacteria" id="ACU71955">
        <property type="protein sequence ID" value="ACU71955"/>
        <property type="gene ID" value="Caci_3046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3046"/>
    <dbReference type="HOGENOM" id="CLU_2664355_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="8479" checksum="E699F7B70C779F8D" modified="2009-10-13" version="1" precursor="true">MIAIILITLLVIGVLTLTGLLVMAHRDNEQLREDLSQTVPFRDSEFAKPFVPPQQPKWQAAEEHLRDPNDVGDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J6</accession>
    <name>C7Q4J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787258.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3056"/>
    <dbReference type="EnsemblBacteria" id="ACU71965">
        <property type="protein sequence ID" value="ACU71965"/>
        <property type="gene ID" value="Caci_3056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3056"/>
    <dbReference type="HOGENOM" id="CLU_2380943_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="94" mass="10530" checksum="75C5A22524E2598F" modified="2009-10-13" version="1">MASQTRLKPTGLTQLAERNPTRWSWPKTGKPRIKQIAEDAGIGRVTLHEVKRGTRVPSQNVQDRLRDLAVSTGVTHSYAHKMLFEPVEIDEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S3</accession>
    <name>C7Q4S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793600.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5011"/>
    <dbReference type="EnsemblBacteria" id="ACU73871">
        <property type="protein sequence ID" value="ACU73871"/>
        <property type="gene ID" value="Caci_5011"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5011"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="VTETDMN"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="26166" checksum="2959A449411C0FA2" modified="2009-10-13" version="1">MNEQTCHRFTDRVAVVTGAAGGIGAATARRLAAEGAAVIAVDIADDAGRAVAEEITASGGRAEYRSGDVASAAAWDALAEHVQGRYGRLDVLHSNAYKVVVKPAHELTEPEWDGQLAVTLKAAWLGVRAFAGMLGESQGSIVLTSSVHALVGLPGHPAYAAAKGALCALGRQLAVEYGPRVRVNTVLPGPILTAAWDRVDAERRAASVSETVAGRFGRPEEVAAAVAFLASADASFVTGANLVVDGGWSVVKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4W9</accession>
    <name>C7Q4W9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small-conductance mechanosensitive channel-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5057"/>
    <dbReference type="EnsemblBacteria" id="ACU73917">
        <property type="protein sequence ID" value="ACU73917"/>
        <property type="gene ID" value="Caci_5057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5057"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095581_0_0_11"/>
    <dbReference type="OMA" id="RCATNDI"/>
    <dbReference type="OrthoDB" id="1979115at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="24590" checksum="D309FB8232AC9194" modified="2009-10-13" version="1">MQDRSVSTGAGTEREPLLIPASHAEVPDLRTRAGRNLRQVILRRGAFASAIAVVALVVSYHYGGLVGAGGHQSLHLVLAFAGAVVFLVSAVIAVRCATNDILGLVHVPGRLSDARASTLRILCLLFGYILVVFGALSLLRVPVGHLLLGGVLTGVILGIAAQQVLANVFAGITILFAKPFTIGDELRIRSGALGGPIVGRVSGMTLTYVTVRTAAGPVLVPNSAVLAAAVGPAQEWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q518</accession>
    <name>C7Q518_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5107</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H(+) + phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:10604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="3.1.4.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:10605"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial phospholipase C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793695.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5107"/>
    <dbReference type="EnsemblBacteria" id="ACU73966">
        <property type="protein sequence ID" value="ACU73966"/>
        <property type="gene ID" value="Caci_5107"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5107"/>
    <dbReference type="eggNOG" id="COG3511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008770_1_0_11"/>
    <dbReference type="OMA" id="GYYCSLH"/>
    <dbReference type="OrthoDB" id="250274at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034480">
        <property type="term" value="F:phosphatidylcholine phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044003">
        <property type="term" value="P:modulation by symbiont of host process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017767">
        <property type="entry name" value="Bact_PC-PLC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008475">
        <property type="entry name" value="PLipase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05506">
        <property type="entry name" value="DUF756"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03396">
        <property type="entry name" value="PC_PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982791" description="Phospholipase C" evidence="6">
        <location>
            <begin position="33"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="7">
        <location>
            <begin position="480"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="7">
        <location>
            <begin position="600"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="687" mass="73137" checksum="231E08662305C211" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5S7</accession>
    <name>C7Q5S7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoenolpyruvate--glycerone phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.121</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18381"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.7.1.121"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.121" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785318.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1098"/>
    <dbReference type="EnsemblBacteria" id="ACU70024">
        <property type="protein sequence ID" value="ACU70024"/>
        <property type="gene ID" value="Caci_1098"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1098"/>
    <dbReference type="eggNOG" id="COG1925">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045361_0_1_11"/>
    <dbReference type="OMA" id="MVVDMAD"/>
    <dbReference type="OrthoDB" id="2041582at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047324">
        <property type="term" value="F:phosphoenolpyruvate-glycerone phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039643">
        <property type="entry name" value="DhaM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012844">
        <property type="entry name" value="DhaM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38594">
        <property type="entry name" value="PTHR38594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02364">
        <property type="entry name" value="dha_pts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="6">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="7">
        <location>
            <begin position="152"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="23472" checksum="F09D7412F440BA03" modified="2009-10-13" version="1">MNQSPGIVLVSHSANLAAGLRELLTQIASDRVPVAIAGGTDDGELGTSYERIAAAIAEADRGAGVIVLPDLGSSVLTTLTVLEDDPRPDVLLVDAPFVEGAVAAAVTAAAGADLAAVAEAARQARGIAKLGGSELEDAVPPTPQDAPATNSAETATSEVTLPATLHARPAGRLAQEAAKFTSTIRLEYGGKTVNPTGVLTVMSLGATAGGTVTVHAEGPDADAAVETLAAILAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6M9</accession>
    <name>C7Q6M9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5205"/>
    <dbReference type="EnsemblBacteria" id="ACU74064">
        <property type="protein sequence ID" value="ACU74064"/>
        <property type="gene ID" value="Caci_5205"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5205"/>
    <dbReference type="eggNOG" id="COG1247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105867_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="21671" checksum="44547B4C236268C1" modified="2009-10-13" version="1">MIIPANQAGWPDLQAVLRSANCHGCRCYCQRFKSPGSDWKNVSDEERAFRLQTQTSCGDPDAETTSGLVAYRDGEAVGWVSVEPRTAFRALRRSRVLWPGRDEDKDDAAVWAVTCFHIRPGHRRQGIAGELALATVPFARDRGAKALEAYPMVTEPGDPVPWGEAHVGTRAMFQDAGFVEVSRPTPRRVVMRVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6U6</accession>
    <name>C7Q6U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795687.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7129"/>
    <dbReference type="EnsemblBacteria" id="ACU75959">
        <property type="protein sequence ID" value="ACU75959"/>
        <property type="gene ID" value="Caci_7129"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7129"/>
    <dbReference type="eggNOG" id="ENOG502ZCDI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093484_0_0_11"/>
    <dbReference type="OMA" id="AFAGAHE"/>
    <dbReference type="OrthoDB" id="1918376at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="19607" checksum="F48C7B060E78081D" modified="2009-10-13" version="1">MSTTTADAGRSPLTRLYLTRGVLAVAWAAAFADAYKAHESLSAAAVTLLIAYPLLDAVSSVVDYRLGPDGPERRVTAFNGVLSTLAAIGVGIAGGASGAAAALATFGAWAVLSGAAQVAVGLRRRGPELGKQWPMLIAGGLSFVVGVFYDAQAAGDKPSLSVLSVYATGGGIFFIVQAALLAWKARRGTVQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6W7</accession>
    <name>C7Q6W7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide/dipeptide ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795708.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7151"/>
    <dbReference type="EnsemblBacteria" id="ACU75980">
        <property type="protein sequence ID" value="ACU75980"/>
        <property type="gene ID" value="Caci_7151"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7151"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_11"/>
    <dbReference type="OMA" id="CHFPEDP"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="29"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="360" mass="38676" checksum="3DE27C0AF9C54775" modified="2009-10-13" version="1">MSAVPPPQPSPAEPDPLLDITGLAKHFPVRRGAVVPRRIGAVKAVDGVGFTVARGESLGLVGESGCGKSTTGRLITRLLEPTAGTIRYDGRDITHAGRRELMPLRGKIQMVFQDPYASLNPRHTVGEIIAAPLESLGVGTSASRRGRVLELLETVGLDAAHVHRYPHEFSGGQRQRIGVARALATEPELIVADEPVSALDVSIQAQIVNMLRRLQRDLGIAMVFIAHDLAVVRQVSHRVAVMYLGRIVEVADRDTLYERCRHPYTQALLSAIPEIDDGAGRGTGTSTSTERIRLVGDVPSPLNPPSGCRFRTRCPKAQDLCAAETPPLVRIDGSAEGHLTACHFPSPVNQTSVIGRDVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q826</accession>
    <name>C7Q826_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5334</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793922.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5334"/>
    <dbReference type="EnsemblBacteria" id="ACU74193">
        <property type="protein sequence ID" value="ACU74193"/>
        <property type="gene ID" value="Caci_5334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5334"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="HERVERY"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="15"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="34959" checksum="8A7E9F3E82BAC4A3" modified="2009-10-13" version="1">MSAGSRSSAGGTASPTLETVAAAAGVSRATVSRVVNGGAKVSPEVRAAVEAAIADLGYSPNRAARSLVTRRTGSVALVVSEPEARVFSDPMLAGITRAIGQALAETDLQLVLMMVPADSGRRRLTRYLLGGHVDGVMLMSLHGDDPLVKELSLASLPVVLMGRPMSPLPIPHVDSDSVDGARQATHHLQALGRTKIATIAGPSDMCAGVDRLLGYRQALDGPGIVARGDFSMASGEAAMTELLAREPDVDGVFAASDLMAAGALRALRAGGRRVPDDVALVGYDDLDVAELTEPPLTTVHQPLSAMARAMVASLLRQIAGDRAPESVVLPNALVVRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q877</accession>
    <name>C7Q877_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795793.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7236"/>
    <dbReference type="EnsemblBacteria" id="ACU76065">
        <property type="protein sequence ID" value="ACU76065"/>
        <property type="gene ID" value="Caci_7236"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7236"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060397_0_1_11"/>
    <dbReference type="OMA" id="AWDSFFH"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="67"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="25289" checksum="B67E48E96B405092" modified="2009-10-13" version="1">MVIGKPGASPREGLAGSADQAWVEREQAQARAYDAIGARYDEAFPHKEGQLAVVTMLLERLPVGARVLDVGTGTGLPTARQLADAGCRVAGLDISPRMIEIARGNVPEAEFVLGDVLDLDVTDPRYEAVTAFFSLLHLPRGQVHAALGLIHEALVCGGWFAVAMVEADVDDVPIAFLDSRVRVTGYLRGDLRSVLTESGFTIEHEQVLSYAPETSSAQPEIQMFFLCRKADRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H9</accession>
    <name>C7Q8H9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prolyl oligopeptidase</fullName>
            <ecNumber evidence="5">3.4.21.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.26" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795895.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7340"/>
    <dbReference type="MEROPS" id="S09.076"/>
    <dbReference type="EnsemblBacteria" id="ACU76167">
        <property type="protein sequence ID" value="ACU76167"/>
        <property type="gene ID" value="Caci_7340"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7340"/>
    <dbReference type="eggNOG" id="COG1505">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011290_1_1_11"/>
    <dbReference type="OMA" id="ACMTQRP"/>
    <dbReference type="OrthoDB" id="315644at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="485"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="709" mass="78376" checksum="ACDBDCD355E1134C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M7</accession>
    <name>C7Q8M7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785586.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1369"/>
    <dbReference type="EnsemblBacteria" id="ACU70292">
        <property type="protein sequence ID" value="ACU70292"/>
        <property type="gene ID" value="Caci_1369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1369"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_12_4_11"/>
    <dbReference type="OMA" id="ARQYLSM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041490">
        <property type="entry name" value="KstR2_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17932">
        <property type="entry name" value="TetR_C_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="22379" checksum="C440E6204439357D" modified="2009-10-13" version="1">MPKPPASDRRAELLALAAGLFAERGYKNTTVRDIADAAGILSGSLYHHFDSKETMADEILRTFLDELFRDYRAIVERQSDPRRAFEQLVDASFQAIDRSHAAIALYQNEAKQLRQSPRFAYLDDTDREFREIWLGTLEKGIASGAFRADLDATMAYRFVRDTVWVAVRWYTPGGKLTAEAVSAQYLSMILEGFQSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8S9</accession>
    <name>C7Q8S9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785638.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1421"/>
    <dbReference type="EnsemblBacteria" id="ACU70344">
        <property type="protein sequence ID" value="ACU70344"/>
        <property type="gene ID" value="Caci_1421"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1421"/>
    <dbReference type="eggNOG" id="COG1378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056943_2_0_11"/>
    <dbReference type="OMA" id="GMEILMA"/>
    <dbReference type="OrthoDB" id="1036370at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="260"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="39712" checksum="ABE85828A30155A4" modified="2009-10-13" version="1">MLEAFGVSSAAEKLYLHLLREPDLRIEAISGELGWPEDEVRAALDELSGLALLRTSPAHPRTLRPVAPDVGLESLLTTLQADLVARQHQMESGRAALAMLTAEYADLHRRGDRTVTEELVGVEEVRTRLKTLSAQAQTEVIALVPDPIQRPDTLAASKPLDAALLGRGVAMRTIYLNSIRNDPASIAYTDWLAGVGGQVRTAPTVPLRLIVFDRTTALVPLDPRDTSAGATVLTGIGVVSAMCALFEQIWATANPLGLPNPPDTQGLGPEEREILRMLANGETDEHIARRLGVSTRTVGRKASELMRRLGTRSRFQMGVRASELGWLDPPQEPLDDDLDGSACLRPAVRAVESRYCDHPVGLRHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T4</accession>
    <name>C7Q8T4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785643.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1426"/>
    <dbReference type="EnsemblBacteria" id="ACU70349">
        <property type="protein sequence ID" value="ACU70349"/>
        <property type="gene ID" value="Caci_1426"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1426"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="MYREQVS"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="105"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21490" checksum="EC1FF687C376DFC9" modified="2009-10-13" version="1">MDIDDEQRFREFVGARSKALLQTAYLLTGDWEHGRDLVQSALAGVARRWSQLADPSQAEAYARKAIYHAHVDRTRLMSWRRERTTASPPDTAAARSDPADLVASRRDLIAALRQLPRGQRAVVVLRYFEDRTDEDIAEVLGISTGTVRSQHHKALKALRVSASIAVDDGEQDIAKDLKKDTALNTVKEEAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q957</accession>
    <name>C7Q957_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3471"/>
    <dbReference type="EnsemblBacteria" id="ACU72377">
        <property type="protein sequence ID" value="ACU72377"/>
        <property type="gene ID" value="Caci_3471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3471"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166206_0_0_11"/>
    <dbReference type="OMA" id="HDDLEME"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="22"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12300" checksum="F211F9BEBED42CC2" modified="2009-10-13" version="1">MSVETTTSDIGAGNAEAVLAEVAAMLRSILDEYALDDIDIEWNTRFHDDLELESVDLVTLAGMLAERYGERVNLAEFIADLGLEEIIELTVGQLVEHVTTALKNPSSSDAEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y7</accession>
    <name>C7Q9Y7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785679.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1462"/>
    <dbReference type="EnsemblBacteria" id="ACU70385">
        <property type="protein sequence ID" value="ACU70385"/>
        <property type="gene ID" value="Caci_1462"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1462"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023081_1_1_11"/>
    <dbReference type="OMA" id="NSCLMHI"/>
    <dbReference type="OrthoDB" id="647535at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="3"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="119"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="24699" checksum="1B500B3FD3ABA2B9" modified="2009-10-13" version="1">MRVALFITCYNDALFPDTGKAVTAVLERLGHTVEFPAAQTCCGQMHHNTGYRREADSLVGAFNDAFRGYDAIVTPSGSCGGHVRHHHRTETAPNVYEFSEFLVDVLNVTDVGAYFPHRVTYHPTCHSLRMLRVGDKPLQLLRAVEGIDLVELPEAESCCGFGGTFAMKNSETSVAMLQDKMGNVRKTGAQTLCASDNSCLMHIGGGLSRVKSGVRTLHLAEILAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA70</accession>
    <name>C7QA70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785762.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1547"/>
    <dbReference type="EnsemblBacteria" id="ACU70468">
        <property type="protein sequence ID" value="ACU70468"/>
        <property type="gene ID" value="Caci_1547"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1547"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_2_11"/>
    <dbReference type="OMA" id="VVFAWQD"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041347">
        <property type="entry name" value="MftR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17754">
        <property type="entry name" value="TetR_C_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21053" checksum="E2B5F7879E108183" modified="2009-10-13" version="1">MSLAERKRQLVRDELAEAALRLLARQGFEETTVDDLAAAAGVSRRTFFRYFASKEDVVISSVVVVTEGIVAEVAARPADEPPAVAIREAVKTVTLEDFAENREKSVALIRHTQNIPALRARFAERQDLLRDDLAAVLARRAGRDTIAPRDQFAAGLGLLAFVGALQYWAASDGRADPAAVLDSAFEEAGQAFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAT8</accession>
    <name>C7QAT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5552"/>
    <dbReference type="EnsemblBacteria" id="ACU74411">
        <property type="protein sequence ID" value="ACU74411"/>
        <property type="gene ID" value="Caci_5552"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5552"/>
    <dbReference type="eggNOG" id="COG5031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_666813_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="43678" checksum="ABAC5F3CA18A12DA" modified="2009-10-13" version="1">MSCGNTAIGAQTTTPRHNELPESAFPEGSRMPVPLPDDASVLLLPPDAAEVACVARGVISAVVPEGGLTGLQQTLLASMFHSLTGFEIDPLAVQAGLAEKPYSATEFAEDLHRRNAAFRGRIVQVMVTAELVLSPLPPRVAKRVAEFAAELSVHDDLEDLLHGHADSGLRLASIDFDRNGYLHDFDVRHAQQLHVGDGALTGPWTPVENDPALAARWASLGDLPTGTLGRGTFDFYKTRGFSFPGSPGSAPPLLAQHDWVHILADYGTRVESEIEVFAFIARANDDLHAFSLLAMVVSLFETGALASGAGLFQADLGHLSQPGMATRFGDALRRAALCTGSNDFMATDWFAVADKPVAVLREELRLPPKSAEAVGAGSVGPWDTGGISPYQLNAGRTLAAAEGREYTGPAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW8</accession>
    <name>C7QAW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5582</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794170.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5582"/>
    <dbReference type="EnsemblBacteria" id="ACU74441">
        <property type="protein sequence ID" value="ACU74441"/>
        <property type="gene ID" value="Caci_5582"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5582"/>
    <dbReference type="eggNOG" id="COG0677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_3_2_11"/>
    <dbReference type="OMA" id="CPERTIQ"/>
    <dbReference type="OrthoDB" id="295459at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="314"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="43348" checksum="CC011775568BFD99" modified="2009-10-13" version="1">MSESSIGVFERDVVVIGGGGHVGLPLAIALADGGSRVTVYDVSARAVELVNSATLPFDEPGAAPVLERVVASGALVASTDPAVVGTAENVIVVIGTPVDEHLNPDQTAIPRALQTCAPYLRDGQLMVLRSTVYPGVTELVERMIARLGVDVDVAFCPERIAEGKAMTELFELPQIVSGRTEAAQSRAAALFSRLTDTIVPLSPEEAELAKLFTNTWRYIKFAAVNQFYMMANDRGLDFERIRAGLSQDYPRAADMPGAGFAAGPCLFKDTMQLAAFHNNNFTLGYAAMTTNEGLPLYVVDRLDAQYDLKNMTVGILGMAFKGGSDDIRSSLSYKLKRILKFKASEVLCTDPLVTVDPSLVPLDKVLAEADLLIIGAPHQEYRDLKTDLPVADIWNSLGDGVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ7</accession>
    <name>C7QAZ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5611"/>
    <dbReference type="EnsemblBacteria" id="ACU74470">
        <property type="protein sequence ID" value="ACU74470"/>
        <property type="gene ID" value="Caci_5611"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5611"/>
    <dbReference type="eggNOG" id="COG0391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044041_1_0_11"/>
    <dbReference type="OMA" id="VEHENAR"/>
    <dbReference type="OrthoDB" id="665169at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="43763" checksum="7B684ACCB28DBD69" modified="2009-10-13" version="1">MIPGDRADSRRVIQNEVVPTISGNLFRPDPATPLAPGTNAVPGAHAVSGAHAAPPGGNPLGGTVPPPLPGTPMTGAAAAAAHWSDPALEDAPTVEFKAYNMAVDGRPAPSVVALGGGHGLSATLAALRTVTDALTAIVTVADNGGSSGRIRRELGGLPPGDLRMALAALCGDDEWGRTWADVLQHRFGGPSEGGLHGHAVGNLLIAALWERLGDPVRALDWVGRLLGARGRVLPMSTVPLEIEALVAGADPAAPGATGVIRGQHELAVTPGRVLSVRLSPPEPPAAPEAAAAIRAADWTVLGPGSWFTSVIPHLLVPELCAALAETKARKLLVFNLSPQPGETDGFSAEQHIEVLADHCPGLRLDLVLADETSCGAPRVHGPMEKAAAALGARVVLAPLAAPYRAGDKSPRHDHALLARAFRGVFAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB27</accession>
    <name>C7QB27_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7493"/>
    <dbReference type="EnsemblBacteria" id="ACU76318">
        <property type="protein sequence ID" value="ACU76318"/>
        <property type="gene ID" value="Caci_7493"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7493"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="YKWMPPL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="33037" checksum="34AAF1BAA13CD886" modified="2009-10-13" version="1">MKAVVIPEFGDAEVLREVVTAVPEPGAGQVSIDVAYAGANFAEVLYRRGVVDVPLPFVPGIEVSGRVRAIGEGVSGLTVGQPVAALTIVDSGGYAEVAVTAADLVAPLAESTDLDPGSALDLATAAALPSNSTTAFLVLDQIARLAPGESVLVHAAAGGVGSQLGQVARLLGAGRVVGTVGSAAKVETARGFGYDEVILRDDLASAGQFDVVVDMVGGPARQGSLDRLAPLGRLVVMGNASGAEDVGISANELWFSNKTVSGFNLAAYSAVHPDRAGQALRRAVRAASEGTLRVQVEAVPLSQVVETHRRIESGSTTGKLVLEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB49</accession>
    <name>C7QB49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7515"/>
    <dbReference type="EnsemblBacteria" id="ACU76340">
        <property type="protein sequence ID" value="ACU76340"/>
        <property type="gene ID" value="Caci_7515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7515"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_1_11"/>
    <dbReference type="OMA" id="WRILYFP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="92"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="34760" checksum="0435DCDC76923CB0" modified="2009-10-13" version="1" precursor="true">MTTEIRNPVAADSVLSGRRRSGALPGKPFWRRLGPWLYLSPLLLFIGVFKVWPTVWGVYLSFFHVRPYLGNQYAGTANYSKLFSDADLRTAVVHTLLDAVFAVSGSIFVGFWLAVLLQGPARHIRILRTAVFLPTVIAMVAAAELWTTLLYPSPYGSVNSLLGKIGIGPEPFFESPHSALASVILMQIWKNAPYDMVIFVAGLASIDREMYEACEIDGASWGQRLRFVTLPALRPITTIVLVLGIIRGLRVFTDIWVSTNGGPAGSSESVVTYLYRQFSQNNDTGYAAAIGTVLLVVTMALTCLMLLWRRRREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB72</accession>
    <name>C7QB72_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76363">
        <property type="protein sequence ID" value="ACU76363"/>
        <property type="gene ID" value="Caci_7538"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7538"/>
    <dbReference type="eggNOG" id="ENOG502Z7UK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_456223_0_0_11"/>
    <dbReference type="OMA" id="GPRYERD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="566"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="617" mass="67642" checksum="1F1C4EC0AE434F64" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH6</accession>
    <name>C7QBH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785847.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1632"/>
    <dbReference type="EnsemblBacteria" id="ACU70553">
        <property type="protein sequence ID" value="ACU70553"/>
        <property type="gene ID" value="Caci_1632"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1632"/>
    <dbReference type="eggNOG" id="COG0663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064827_4_1_11"/>
    <dbReference type="OMA" id="HYVHNAQ"/>
    <dbReference type="OrthoDB" id="1242595at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="17895" checksum="4E53959F6008CD9A" modified="2009-10-13" version="1">MAVYAIGDAVPEIHPDAYIHPDATVIGQVSVGAGSTVWPGAVLRGDYGRITVGDRTSIQDGTVVHATEMLPTVIGSDCVVGHIAHLEGCVVEDGCLIGSGSVVLHRAVVRTGALVGANAVVSNGVEVPSRAMALGVPAKIRENTVPEGSFDDAVARYVANGKRYREELRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBI2</accession>
    <name>C7QBI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785853.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1638"/>
    <dbReference type="EnsemblBacteria" id="ACU70559">
        <property type="protein sequence ID" value="ACU70559"/>
        <property type="gene ID" value="Caci_1638"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1638"/>
    <dbReference type="eggNOG" id="ENOG5030NZ9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069776_1_2_11"/>
    <dbReference type="OMA" id="FDGPRWF"/>
    <dbReference type="OrthoDB" id="1206711at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022183">
        <property type="entry name" value="DUF3710"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12502">
        <property type="entry name" value="DUF3710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="27797" checksum="55BD17D779244869" modified="2009-10-13" version="1">MVFRRGQKGDSDRRDRVSEADAYGDLSEIKDEERKISLADVSRAAGPWDFNEVEDPKAGRVDLGALLVPAVEGMELRLEMADAEQVIAATVVSRQSAVQLQAFAAPRSEGIWAEVRAEIALEISKQGGTVDERDGPFGIELRAQVPVQAPDGSRGVQLVRFIGVDGPRWFLRGVVSGQGAVQPKEALDIEHVFRDTVVSRGNTPMAPRDPIPLRMPAEAQEAMQQQAVPAEEGSQYTQGDLNPFERGPEITERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBJ7</accession>
    <name>C7QBJ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="8" type="ordered locus">Caci_1653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785868.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1653"/>
    <dbReference type="EnsemblBacteria" id="ACU70574">
        <property type="protein sequence ID" value="ACU70574"/>
        <property type="gene ID" value="Caci_1653"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1653"/>
    <dbReference type="eggNOG" id="COG0275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038422_0_0_11"/>
    <dbReference type="OMA" id="NPAKRTF"/>
    <dbReference type="OrthoDB" id="1272633at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="37"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="285"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="34422" checksum="6A43A1F96477D6A1" modified="2009-10-13" version="1">MTSATHIPVMLERCVEILGPALERPGAVVLDATLGLGGHSEAFLRRFPDVRLIGLDRDPQALEASGRRLAPFGERATLVHAVYDEIPDVLERLGVAELSGTLFDLGVSSLQLDMRERGFAYSYDAPLDMRMDSSRGITAADIVNTYPAADIARILRDYGEERFARRIADRIVAEREKEPFTTTARLSDLVRDSIPAATRRTGGHPAKRAFQALRIAVNDELPVLERALPAAVAATGLGGRIAVLSYHSLEDRLVKRVFAKASESAAPPGLPVVPEQYQPKFRLLTRGAEPPTDAETAENPRAASAKLRAAERVREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC03</accession>
    <name>C7QC03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3720"/>
    <dbReference type="EnsemblBacteria" id="ACU72622">
        <property type="protein sequence ID" value="ACU72622"/>
        <property type="gene ID" value="Caci_3720"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3720"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="FPYLING"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="99"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="35469" checksum="E48C4A23BA9FB4E5" modified="2009-10-13" version="1">MTDRHDVVEAPAGLDDRIPLPAAGRPRNARRPRRGLLTRATPWLFLAVPLVLLATFTYTPIANMLYYSFTDWDGFSPDRHLVGSANYTELFTRPDLFRVFFVSLFYLASGAVQMVLALYFATVLSFNVRFKNFFKGVLFFPYLINGVAIGFVFLYFFQPGGTLDSVLRLAGVHSQHLWLGDPKLANWSLAGVSLWRYLGLNFVLFLGAIQSIPGDIYEAADLDGANRWHQVRYLILPGIRPVVSLAAILVVSGSLSVFEIPYIMTGGAGGTTTFVIQTVKLAFQFNKVGLASAAAVVLLGIVLVVTWVQRLLVPDEGVDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCV2</accession>
    <name>C7QCV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785956.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1741"/>
    <dbReference type="EnsemblBacteria" id="ACU70662">
        <property type="protein sequence ID" value="ACU70662"/>
        <property type="gene ID" value="Caci_1741"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1741"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101396_0_0_11"/>
    <dbReference type="OMA" id="WVVGTPW"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19975" checksum="D142E10A4C5C3CA4" modified="2009-10-13" version="1">MFREPTTTARLVLNSVTEADAREMAEVLADPELYTFIGGEPPTPEGLRARYARLAVGRSPDGLQEWVNWIARRAQDGAAVGTVQATVVDGGRRADVAWVVGTAWQGRGYAVEAASALVAWLRERGVAEIRANIHPRHAASAKVAERIGLAPTGETDGEGEQIWRAQGAPEHVLDEDPERTEKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCW1</accession>
    <name>C7QCW1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTPase EngC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1750"/>
    <dbReference type="EnsemblBacteria" id="ACU70671">
        <property type="protein sequence ID" value="ACU70671"/>
        <property type="gene ID" value="Caci_1750"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1750"/>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2205297_0_0_11"/>
    <dbReference type="OrthoDB" id="908180at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="11514" checksum="00CB87F7D364E9AB" modified="2009-10-13" version="1">MGSQRLRALGWTEGHEKAFAVLQEAAGADLIPALVTEAGDGGCTAESATGALRATYGPNLLLSMAADPLRRPLTEDWIAVRRWPDGRATAEAILSRRVTLMRQEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY6</accession>
    <name>C7QCY6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1775"/>
    <dbReference type="EnsemblBacteria" id="ACU70696">
        <property type="protein sequence ID" value="ACU70696"/>
        <property type="gene ID" value="Caci_1775"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1775"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039939_0_0_11"/>
    <dbReference type="OMA" id="LMNQLRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="42234" checksum="F9187226C3012229" modified="2009-10-13" version="1">MSVPAASGADRSDIVLPAYGRGALSDLLPAVLAALGVEGSPDPFGLAPTRRACVFLVDGMGARLIERNAEVAPYLAKALRASRALTAGFPSTTAASIGSLGTGLPSGASGMLGYRVLVPGTSRMINLLRWDAPVDPVEWQPHETVFERAEREGIEVTQVTAARFQESGLTRSVLRGGAFTGAESLPNRVAGALQTLQDAADRDARALVYLYYADLDAAGHLNGVDSESWRQQLAVVDATVRELVDRLPAGTALYVTADHGMVDVPAERRVDVDEDYELQVGVRLLGGEGRARHVYAKPGAARDVLQIWREALEDVAVVRSRQEAIYEGWFGPPESVDDRLAPRIGDVVAALLEDWAVVATRREKLESRLLGMHGSLSAAEQEIPLLVFAPEGGPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ8</accession>
    <name>C7QCZ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786002.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1787"/>
    <dbReference type="EnsemblBacteria" id="ACU70708">
        <property type="protein sequence ID" value="ACU70708"/>
        <property type="gene ID" value="Caci_1787"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1787"/>
    <dbReference type="HOGENOM" id="CLU_1861604_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14929" checksum="6D87E70798A1EC76" modified="2009-10-13" version="1">MSSDQDSEDDPDEPFIPLGSEELPAEPPADDTRGAHTAIARSLYPNIPRVLRKEARSFFDGAMYAYTEGDLPGARLSFLAVAAIGDPDTAPAALVFLGVIAFRRRDAIEARMWFTRAASGPDDHWALVAAQELRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD98</accession>
    <name>C7QD98_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin iron-sulfur binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792420.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3789"/>
    <dbReference type="EnsemblBacteria" id="ACU72691">
        <property type="protein sequence ID" value="ACU72691"/>
        <property type="gene ID" value="Caci_3789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3789"/>
    <dbReference type="eggNOG" id="COG1148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_5_5_11"/>
    <dbReference type="OMA" id="DMCPLDS"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="76" mass="8255" checksum="5C46B13BEDA93B3F" modified="2009-10-13" version="1">MPLIENSRSDVPVTIDESLCIEGCTLCVEVCPLDSLAIDAETGKAYMHVDECWYCGPCAARCPTGAVTVNMPYLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDG5</accession>
    <name>C7QDG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792487.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3864"/>
    <dbReference type="EnsemblBacteria" id="ACU72758">
        <property type="protein sequence ID" value="ACU72758"/>
        <property type="gene ID" value="Caci_3864"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3864"/>
    <dbReference type="HOGENOM" id="CLU_2153807_0_0_11"/>
    <dbReference type="OrthoDB" id="865342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="12445" checksum="35FFB800D21B8C46" modified="2009-10-13" version="1">MAEGRHPRNHPAGHGATDCTVCLDVEAWTVERDAQLMKIASDSELPWRQRNTETTDLLRRPLTILALATRLASGQDADVTRLQLLHDHPKTIIQRRRPSAACGKRCPDWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE29</accession>
    <name>C7QE29_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7793"/>
    <dbReference type="EnsemblBacteria" id="ACU76617">
        <property type="protein sequence ID" value="ACU76617"/>
        <property type="gene ID" value="Caci_7793"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7793"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_803889_0_0_11"/>
    <dbReference type="OMA" id="RFIDFEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="41"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="36832" checksum="2F8CDB1218F1DEF0" modified="2009-10-13" version="1">MRGMRSVPLLGDVLTAQLGAPKRVKTLSSSPRSAVWRAAFGGTPAVIKHLVPGDGADDFFAREVAALQAASAVQPPVVPRLLGADPVERTLVTEYVEERPPAANWVVAYAAALGRLHGAPTEGVDLPRWNGPTSADVEAFVKLAAWLGATDTDKASAELEDLLTRLKTRSSRRDLLHGDPCPTNDLHTAQGVRFIDFEQASLGDGMVESAYLRIGFPTCWCSTTQPPELLAEAEAAYSAASGRTIDEHELADACTSWTIRGDALVERAFRETQDHLARLAVEDWKWWTVSARDRLAYRLGVIGGLAADDGPLGETARLAGWMRAAMLARWPGLRPLPAKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE77</accession>
    <name>C7QE77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7841</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796390.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7841"/>
    <dbReference type="EnsemblBacteria" id="ACU76665">
        <property type="protein sequence ID" value="ACU76665"/>
        <property type="gene ID" value="Caci_7841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7841"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="VTCSISA"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="32159" checksum="98B862912FC280FA" modified="2009-10-13" version="1" precursor="true">MIEIENLTKRYGARYAVRDLTFSVRPGRVTGFLGPNGAGKSTTMRAVLGLDLPTAGRVLVDGRPYAALERPLTHVGMLLDTGGVHPGRSARQHLRAVAAAGKLSERRVDEVLARVGLTDVSQDRVGGYSLGMRQRLGIATALLGDPGILMFDEPVNGLDPEGIRWIRDLMKGLAAEGRTVFVSSHLMSEMESTADHLVVIGRGRLIADLPARELIERYGGGFLSVRTDDPGRLITVLAAAGAQVAPEGPDTLRVVGMAGDAVARLAYQAGVLVLDVVRRATSLEDAYLQLTDAAVEYRGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA3</accession>
    <name>C7QEA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbon monoxide dehydrogenase subunit G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786088.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1874"/>
    <dbReference type="EnsemblBacteria" id="ACU70794">
        <property type="protein sequence ID" value="ACU70794"/>
        <property type="gene ID" value="Caci_1874"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1874"/>
    <dbReference type="eggNOG" id="COG3427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046420_0_1_11"/>
    <dbReference type="OMA" id="YEAIVTQ"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05018">
        <property type="entry name" value="CoxG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010419">
        <property type="entry name" value="CO_DH_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38588">
        <property type="entry name" value="PTHR38588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06240">
        <property type="entry name" value="COXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="22343" checksum="D574FB0347DCA3F3" modified="2009-10-13" version="1">MKVSGSAVLNADVGRVYEALTDPRTLAAAIPGCERLEMVAPDIYDMVVTVGVGSIKGTYKGRVELADQSAPRSFTLRASGAGAPGTVSAECRMLLVDEAAARTRVEYDADAVIGGVVGGVGQRMLGGVARKLAGQFFTGMNGVLTRDGVPAPAQDQAELVPATVLHPATGPVAAFPIAAPSGQPGTSPAVVALAAGLAGAAAALSGVVLGYVMGRLSGRRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA9</accession>
    <name>C7QEA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786094.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1880"/>
    <dbReference type="EnsemblBacteria" id="ACU70800">
        <property type="protein sequence ID" value="ACU70800"/>
        <property type="gene ID" value="Caci_1880"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1880"/>
    <dbReference type="eggNOG" id="COG1975">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041115_1_0_11"/>
    <dbReference type="OMA" id="IGQHLIT"/>
    <dbReference type="OrthoDB" id="1879870at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="207"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="370" mass="38563" checksum="084D4A49D1BAF4E7" modified="2009-10-13" version="1">MRDLLPTLLAWRAAGEPFVLATVVAADGGGPREPGAAMAVRMAGGVPGDVVGSVSGGCVEASVIEAAADVVAAGRPRLETYGLEDSEAVGLTCGGTLSVFIEPGAAASAHLDRVQEAVARGSGAAMVTVVDGPPELIGLHRGDLLRANGYAALADAVARDADALVDLGEPARRRYRLDGCPEPADGPWGAPDTVTVFFNVIGAPPRLIVLGALDYAASLASIGRFLGYWVTVCDARPVFATAERFPDAHDVVVAWPHQYLAATSIDERTAICVLTHDPKFDVPALEIALRSPALYVGAMGSRRTCEDRERRLREAGVTEDELARLAAPIGLDLGASTPAETAVSIAAELVALRRQGSGEPLRRTRGKIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEH0</accession>
    <name>C7QEH0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1941"/>
    <dbReference type="EnsemblBacteria" id="ACU70861">
        <property type="protein sequence ID" value="ACU70861"/>
        <property type="gene ID" value="Caci_1941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1941"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047233_0_0_11"/>
    <dbReference type="OMA" id="VYGVWYS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022386">
        <property type="entry name" value="Chitin_NgcE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03851">
        <property type="entry name" value="chitin_NgcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983084" evidence="2">
        <location>
            <begin position="34"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="51827" checksum="7F74EC7CE4226602" modified="2009-10-13" version="1" precursor="true">MSDHGLPADVSRRQMLVRSAAIAAMVGPGSALAAGCAAGSGSSPKNNNAGSTTAANSSDPKNPFGVKASSPLDVYVFKGGYGDDYAKAFEAMYSSKFSGSQVSHHSGQNLTGDLQPRFNAGSPPDVIDDSGAQQLKLDVLNSSGQLTNLDRLLDAPSIDDPSKKVRDTLLAGTIETGQLGQSMFSLNYAFTVFGLWYSTALFQKNNWQVPTSWEDFMTLCATIKASGIAPFAHQGKYPYYMLVPLMDMVAKNGGPDVQTAIDNLEPNAWKSDAVKNSVDALYELVDKGYMLPGTEGLTHIQSQTLWNQGKAAVIPCGSWLENEQLSATPAGFNMAVFAMPSLSGDKMPQTAIRAGAGEPFIVPSKAKNPAGGLEFLRIMCSKAGGASFAQKANSLSVVKDAITPDIEAKLLPGTKSSNDLYQAANGKVISWYYLNWYSQMEKDLEDAMGQLMANKIKPAEFITRAQAAADKCAGDSSVQKFKRPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEK0</accession>
    <name>C7QEK0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786184.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1971"/>
    <dbReference type="EnsemblBacteria" id="ACU70891">
        <property type="protein sequence ID" value="ACU70891"/>
        <property type="gene ID" value="Caci_1971"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1971"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048587_0_0_11"/>
    <dbReference type="OMA" id="EFYDYYR"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983086" description="DLH domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="32239" checksum="C62DFAB671225D3F" modified="2009-10-13" version="1">MRTDVTFTSNGLKISGHLHLPQTIAAADTATPAPAVVVGHPGTGVKEQAAGLYAGRLAAAGFIALAFDAAYQGESQGEPRGLEDPAQRVEDLKSAVSFLTTHPAVDPDRIGVLGICASDGYGLTAAATDHRIRAVATVSGVDIARQFKVGADGTQDPALFQSLLDAAAAARTAEARGEGGQTFSLFPATAQEAELGGPHAFEGWEYYCTPRAAHERSAKTLTWSSVDRIATFDGLATVSLIAPRPLLLIAGRQAVTSWMSVHAFQNATGPKELHWIDGASHVDLYDKDEYVTPAIAKLAEFYTANLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER7</accession>
    <name>C7QER7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792566.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3956"/>
    <dbReference type="EnsemblBacteria" id="ACU72837">
        <property type="protein sequence ID" value="ACU72837"/>
        <property type="gene ID" value="Caci_3956"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3956"/>
    <dbReference type="eggNOG" id="ENOG5031CCI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101801_0_0_11"/>
    <dbReference type="OMA" id="VINAPGQ"/>
    <dbReference type="OrthoDB" id="1850406at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981581" evidence="2">
        <location>
            <begin position="31"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17063" checksum="A15AB8EC3C3A8734" modified="2009-10-13" version="1" precursor="true">MGMLTVRVLRAVLAVLLTGAVLVQALMVWALASGSDPEDGTLPLTALRVITILGIGTIQVALVCVWRLVVMVRRGTVFSHAAFRYVDGVIGAIVAAALVWFTVTAVNAPRQRDDPGVTGIMAGIGVGILGVALIVLVLRMLLVQAVARDGEAAQLKAELDEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QES5</accession>
    <name>C7QES5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">crcB</name>
        <name evidence="10" type="ordered locus">Caci_3967</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3967"/>
    <dbReference type="EnsemblBacteria" id="ACU72845">
        <property type="protein sequence ID" value="ACU72845"/>
        <property type="gene ID" value="Caci_3967"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3967"/>
    <dbReference type="eggNOG" id="COG0239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114342_2_1_11"/>
    <dbReference type="OMA" id="TGICGSF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU72845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="12646" checksum="0C2E3CD51D98B4A1" modified="2009-10-13" version="1" precursor="true">MGPLVITLIAVSVAAAIGASARYLLDKALTGRCASTLPIGTLTINITGAFLLGLLTGLAAHHGMPKNALTVLGTGFCGAYTTFSTFSYETMRLVEDGSIAEATTNVAVSLTAGMATAAAGLGAALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEW5</accession>
    <name>C7QEW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4017"/>
    <dbReference type="EnsemblBacteria" id="ACU72885">
        <property type="protein sequence ID" value="ACU72885"/>
        <property type="gene ID" value="Caci_4017"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4017"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_7_0_11"/>
    <dbReference type="OMA" id="GYQAREP"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="22440" checksum="F480534F8069A044" modified="2009-10-13" version="1">MSPRHQIVPAQPQDATALSRVIARAFHDLAPSVWLIPDSEGRTRLFPGYFRLFVDEAMARGRVYTTLELTAVALWLPSTPNEEPDSSGYDAGLPAATGIWVDRFRIFDALLAEHHPHDTAHDHLAILAVDPHHQHQGIGTALLAAHHDHLDAEDPPRAAYLEASDATTRELYLRHGYTDLDDPIILPSGAHMYPMLRRTNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFA5</accession>
    <name>C7QFA5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ordered locus">Caci_7859</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796407.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7859"/>
    <dbReference type="EnsemblBacteria" id="ACU76682">
        <property type="protein sequence ID" value="ACU76682"/>
        <property type="gene ID" value="Caci_7859"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7859"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_7_1_11"/>
    <dbReference type="OMA" id="GMDACVP"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32125" checksum="9FFDE37953621619" modified="2009-10-13" version="1">MPQNAHPTEPAADLWSAGAPFGRLITAMITPFQADGSLDLDGAQKLAANLVDAGNDGLVVSGTTGESPTTTDAEQKALLRAVREAVGDRAHVIAGVGTNSTAHTLELARQAEEDADALLVVTPYYNKPTQEGLYRHFTAVADHTSRPVVLYDIPHRSGIPIEVDTLKRLAGHDMIVAVKDAKGDLTAGSEVMAATGLAYYSGDDPLTLPWLSVGAVGVVSMSAHLAAPRIRAMIAAYLAGDVAEAARLHAELLPVHAGVTSLPGVISLKTAMNMLGLPGGPVRLPLVEATEEQQARLKTFLAQGGVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFC0</accession>
    <name>C7QFC0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="13" type="ordered locus">Caci_7874</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796422.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7874"/>
    <dbReference type="EnsemblBacteria" id="ACU76697">
        <property type="protein sequence ID" value="ACU76697"/>
        <property type="gene ID" value="Caci_7874"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7874"/>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_0_1_11"/>
    <dbReference type="OMA" id="HHPNKAD"/>
    <dbReference type="OrthoDB" id="803114at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="11">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="12">
        <location>
            <begin position="116"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="26843" checksum="7964820A159CB8B3" modified="2009-10-13" version="1">MTAALGQGVVKVAVFGAAGRMGQAVCRAVLDAPGLDLVAQIDVDDDPQRAVEAGAEVAVDFTHPGATMQNIEFCARNGINVVVGTSGFDEARQDQVRALLHGTEVRVLVAPNFSIGAVLMMKFAANAAPYFESVEIIELHHPDKVDAPSGTATRTAELVAEARAAAGSAPMPDATLSPSQGGPGLDGARGAAVESIPVHSVRLRGLIAHQEVLLGTVGETLTIRHDSLDRASFMPGVVLACKKTGTLPAGLTVGLDALLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFK8</accession>
    <name>C7QFK8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796510.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7962"/>
    <dbReference type="EnsemblBacteria" id="ACU76785">
        <property type="protein sequence ID" value="ACU76785"/>
        <property type="gene ID" value="Caci_7962"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7962"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_19_1_11"/>
    <dbReference type="OMA" id="YPHMPTG"/>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019880">
        <property type="entry name" value="OxyQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03539">
        <property type="entry name" value="DapC_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="38645" checksum="C2760834EE3C5E0E" modified="2009-10-13" version="1">MRKLPDFPWDRLAPAKARAGQHPDGIVDLSVGTPVDPVPAVVQDALRTGSNAPGYPLTHGTPALREAAVGWMARRLGVSGVAPAAVLPVLGTKELVAWLPMLLGLGPGDQVVIPAVAYPTYDVGARIAGADTLVAAPEDAAELIGARRPKLLWLNSPANPNGRVASAAELRAVVAAAREAGTVVVSDECYIELAWEAEPVSLLHPDVCGGSHEGLLVVHSLSKRSNLAGYRAGFVTGDPAIVADLLEVRKHAGMIMPQPVQDAMAAALNDDAHAAEQKERYRKRREVLRGALEHAGFRIEHSEAGLYLWSTRDEDCWTTVDWLSERGILVAPGDFYGEAGARHVRVALTASDERVAAAAARLIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG1</accession>
    <name>C7QGG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792735.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4142"/>
    <dbReference type="EnsemblBacteria" id="ACU73006">
        <property type="protein sequence ID" value="ACU73006"/>
        <property type="gene ID" value="Caci_4142"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4142"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="GYTPMQW"/>
    <dbReference type="OrthoDB" id="1459004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="215"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="34310" checksum="BDFE62F690506D2D" modified="2009-10-13" version="1">MPTARLRRIAVLVLEGAKPLDVGIPAQVFTTRASMPYEVRVCGAAPGLVTGGDGLAYHVAHGLEALAWADIAFIPGYRAPDRDDPPPAVVAALIAAHEGGTRLAAISTGAFALAATGLLDGKRATTHWHYTRTLAQKHPQIRVDENVLFVDEGSVLTSAGAASGIDLCLHILRGDLGVSAANHAARRLVAAPYRSGGQAQYVPRSVPEPLGERFAATREWALRRLGDPLSLESLAEHAAVSPRTFSRRFMEDTGYTPMQWVTRARVDLARELLERSQRSIEQIANDVGLGTGTNLRAHFQRILGTTPSEYRRTFTRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS7</accession>
    <name>C7QGS7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794686.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6102"/>
    <dbReference type="EnsemblBacteria" id="ACU74957">
        <property type="protein sequence ID" value="ACU74957"/>
        <property type="gene ID" value="Caci_6102"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6102"/>
    <dbReference type="eggNOG" id="COG0325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059988_0_0_11"/>
    <dbReference type="OMA" id="IEWHMIG"/>
    <dbReference type="OrthoDB" id="1423012at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="5">
        <location>
            <begin position="24"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="25828" checksum="AE16AA5F077C3A37" modified="2009-10-13" version="1">MAGDSEDRADEQASDARRGQISENLAAVREDIAAAARKASRDPSEVSLIAVTKTYPASDVRVLAELGVLDVGENRDQEAAPKARATAGLGLRWHFIGQLQTNKASSVAEYADFVHSVDRIRLVAALSRSAVRYDKELTCLVQVDLGNAEPMDDNAARGGAFPDQVPELADAIAAAPGLNLGGLMAVAPLGAEPGPAFERLHTLAMRLRTTHPSATMISAGMSGDLGEAVAAGATHVRIGSAILGIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH33</accession>
    <name>C7QH33_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796608.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8060"/>
    <dbReference type="EnsemblBacteria" id="ACU76883">
        <property type="protein sequence ID" value="ACU76883"/>
        <property type="gene ID" value="Caci_8060"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8060"/>
    <dbReference type="eggNOG" id="COG4034">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_800915_0_0_11"/>
    <dbReference type="OMA" id="DAHHGVN"/>
    <dbReference type="OrthoDB" id="1337686at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010581">
        <property type="entry name" value="DUF1152"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06626">
        <property type="entry name" value="DUF1152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="34782" checksum="D2E0A9C04E484C36" modified="2009-10-13" version="1">MTASATTTSLRELPLFAALADSRRVLIAGAGGGFDVFGGVPLAMALRERGAEVFLGSLTFVSSGFSLDAWLAPDVAAITPASGGFAEYFPERTLARWLKTVGEPSTVYSFQRTGVEPLREAYRALIAHLGIDAIVLVDGGTDILMRGDEAGLGTPEEDMLSLATVAGLDEISVRLVVSIGFGIDSYHGVNHVQVLENLADLDADGAYLGAFSIPRASREGSLYLDAVAYAQENTPSRPSIVQGQIASAMLGVSGNVHFTQRTQNSVLFVNPLMAMYFTVTVEGLAARHLYLPMLEGTQTFRQIATIIGTFRDGLPERRIPRQFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH89</accession>
    <name>C7QH89_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784323.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0073"/>
    <dbReference type="EnsemblBacteria" id="ACU69028">
        <property type="protein sequence ID" value="ACU69028"/>
        <property type="gene ID" value="Caci_0073"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0073"/>
    <dbReference type="eggNOG" id="COG3177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058793_1_0_11"/>
    <dbReference type="OMA" id="VDRVYGH"/>
    <dbReference type="OrthoDB" id="1374721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="2">
        <location>
            <begin position="108"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="27385" checksum="4867388AB5B67CC4" modified="2009-10-13" version="1">MDTRSPIQRLAAAPNAAEAADTAREAVDRVRRHKVLRSQSARVTAESQLRGARASAALGSLSEAGTDWPLEEVRRRTDLGDEDGSGLLRGALRISGELGTLAPVWKRSPIQALSRMHLLAAAGHLDQDRVGRPSGPEAAVTLTTLANELRDPAAAEVPAVVVAAAVHAELLVNEPFGWGDGLLARAASRLILADRGLDPQSLAVVEAGHVDVGVEKYLDAARDYATGTEEGLATWLGLYAEAVELGARESLAVCEAIMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG3</accession>
    <name>C7QHG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784397.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0147"/>
    <dbReference type="EnsemblBacteria" id="ACU69102">
        <property type="protein sequence ID" value="ACU69102"/>
        <property type="gene ID" value="Caci_0147"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0147"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WRREHAY"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="103"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="19364" checksum="B96066DA379328CB" modified="2009-10-13" version="1">MDKSYEAEFAELVAAKGAALRRTAYLMCADWHLAEDLVQTVFVKVHLHWRRIKRQETFDAYLRTTLFRAYLDTRRAKWRRETPAEYLPELEAPGTEPGDDRDVLVAALRRIPPRQRAVLVLRYWEDLSVEETARLLGCAAGTVKSQAARGLAALRPLLAGTPFESVTAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHJ8</accession>
    <name>C7QHJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0182"/>
    <dbReference type="EnsemblBacteria" id="ACU69137">
        <property type="protein sequence ID" value="ACU69137"/>
        <property type="gene ID" value="Caci_0182"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0182"/>
    <dbReference type="eggNOG" id="ENOG503440S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154774_0_0_11"/>
    <dbReference type="OMA" id="TEGITDR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983229" evidence="1">
        <location>
            <begin position="28"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="24429" checksum="AA3315FCEAA5BFC1" modified="2009-10-13" version="1" precursor="true">MTLRTRLSAAAVGALIAVGAVALPAQAATASDPAAGLAKAKAAVTEGITDRLTTLGHLQTALTGYKEVTDAARGTLTQVLSSDVSGLTALKTKVAAETTEAAVRTDGKTMVDDYRVYVLVAPKVHLTHALDVEGAALAKLVKVHDALADRLAKDPTANTAANKALLADMTSQIQSATTAIAGKDAALLALQPTPDGKALTASVKAISAPAKDARDDIKKAVDDAKKVRDALKGTKTTTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV2</accession>
    <name>C7QHV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786420.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71127">
        <property type="protein sequence ID" value="ACU71127"/>
        <property type="gene ID" value="Caci_2208"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2208"/>
    <dbReference type="eggNOG" id="COG2899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034539_1_0_11"/>
    <dbReference type="OMA" id="EYVYLEH"/>
    <dbReference type="OrthoDB" id="1221837at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007427">
        <property type="entry name" value="DUF475"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04332">
        <property type="entry name" value="DUF475"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="356" mass="38307" checksum="D54FCF1279404A6B" modified="2009-10-13" version="1">MRGRDFGVAYGATLLGLVLALWLGGIRSATVVAMLAVLEVALSFDNAVVNATVLRRFDLRWQRIFLTVGVLIAVFGMRLVIPMAVLVAVTRQSPFHVLSSSVHDPNGYAHEILGVQPLIAAFGGVFLLMIAMDFFLSGHDLIWLPFFERRLAAFGERFKPLALEAFQVVGVVLFLFVAAGTFATDHPVGVPIAGVIGLATYFTIKRLSDAAADRSESLADEADETPPQGRQALMLFIYLEVLDATFSFDSVMGGFSVTVDIALFTIGLGIGAAYVRSLTVFLVRKKTLDRYVYLEHGAYYSIGVLAVLLLVEIGPDVPDWLASVAGTSMIVAAFIHSAVKAKGEDPAGAEHPALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI03</accession>
    <name>C7QI03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4184"/>
    <dbReference type="EnsemblBacteria" id="ACU73048">
        <property type="protein sequence ID" value="ACU73048"/>
        <property type="gene ID" value="Caci_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4184"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_2_11"/>
    <dbReference type="OMA" id="SACNNDP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="43735" checksum="A050DCB3B0B0D7C0" modified="2009-10-13" version="1">MTTSTAPEGSSAGSPFPMYTPEFAADPHGAYAEMRRAHGSLVPVLLDPEVPATLVIGYRTAIRILHDQERFPADSRRWEQGVSASCPVRPMMEWRPNALRSAGIEHARYRSSNVYALNGVDLHGLRTVVQDVAAGLINDLSQSGKADLITQYAFPLAFQVLNTLLGCPPEIGERVAIGMAKIFEGIDAEAGNAQLAAALAELVMMKKEHPADDVTTRLLQHESALEVPEMVHQLACIYGAGIEPQQNLIANALLLILTDERFSGDVLDGNLTVRDALDEVLYQDPPMANYALSFPPYPVQIDGVWLPADQPVVISMSACNNDPAIASDHRTGNRAHLAWSAGPHACPAQSAAYLIAQAAIDQILDALPEMELAVPKEDLVWRPGPFARALASLPVVVPGSPSNPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI72</accession>
    <name>C7QI72_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane dipeptidase</fullName>
            <ecNumber evidence="1">3.4.13.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.13.19" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792846.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4253"/>
    <dbReference type="EnsemblBacteria" id="ACU73117">
        <property type="protein sequence ID" value="ACU73117"/>
        <property type="gene ID" value="Caci_4253"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4253"/>
    <dbReference type="eggNOG" id="COG2355">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_2_1_11"/>
    <dbReference type="OMA" id="ADAHNDT"/>
    <dbReference type="OrthoDB" id="1145595at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37714" checksum="48C6A2CADD1A44F1" modified="2009-10-13" version="1">MGTTEGLDASTLELHRRVVVADTHNDLLCSVVLRPVAQWSDYFRAQWLPQLRAGGVDVQVLPVFIDDSFRPEGALRQTLRMIEAAHRIAEGNADEVSLCLDGADIDRALDAGRIALVLALESAPGIDADIELLTTLYRLGVRIASLAHFGRTPLADGSAEDAAGSRLTAAGVEAFAEMERMGMVFDVSHLGAAGVDHVLELATRPLLATHSSARALCDHHRNLTDARLAAIAAGGGVVCVNFFPGFVDAHEPSVSRLVDHIEHIGKVAGTDHVGIGPDFVVEVLRDVTPGGVEIGLMAGCDPFDTLPGLPGPAGLPLLTAELLARGVDEAVIAATLGGNVLRLFRAELGVPAERRGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC2</accession>
    <name>C7QIC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FMN-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794728.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6145"/>
    <dbReference type="EnsemblBacteria" id="ACU74999">
        <property type="protein sequence ID" value="ACU74999"/>
        <property type="gene ID" value="Caci_6145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6145"/>
    <dbReference type="eggNOG" id="COG3976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065810_2_1_11"/>
    <dbReference type="OMA" id="TRWGPVQ"/>
    <dbReference type="OrthoDB" id="1981023at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981667" evidence="2">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="3">
        <location>
            <begin position="106"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="18598" checksum="994C7FBC4902FCA4" modified="2009-10-13" version="1" precursor="true">MRRAIVTGTATVSGVVLLLGLKPHSDTPLADKGTDSKFTITQSDVQGGGSQPSSQPSSQPSSGGSSGSSGSSQPGSPSSSPSSPSSSAPAASGTSKTVTGDAADTRFGPVQVAVTFNGKKITQIQVLQYPTETGRDQEINTYAIPQLNQQAMTAQSAQIDGVSGATYTSEGYQQSLQSAIDKAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL5</accession>
    <name>C7QIL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75092">
        <property type="protein sequence ID" value="ACU75092"/>
        <property type="gene ID" value="Caci_6238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6238"/>
    <dbReference type="eggNOG" id="ENOG502ZSER">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037037_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28929" checksum="8F26B334B7264EC8" modified="2009-10-13" version="1">MGDLGFLVSRLVRRYRDPVVGTLRLTAKDWRGSRVKYVGVVSAPGLSPTPVSYRTSEPTKRWVMDGMDLPVVVDRTRPAKLRILWKQVPTTKQYRANLQAQQMRQAAETAAHMASGDSAAGTPPLHNIFAMRGNLFGDGGDLAQVVSNAISEAFGSQSSTVWGESHVHMQISEGAPIVGGIRGTAIVIAERDVSVPAMFGDAMAGGLVDLTLEVTPPDGVPYPARARLVFSTPERRARIAAVGTRLPIRIDPTRRAHVEIDTAALNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIP7</accession>
    <name>C7QIP7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ThiamineS protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796672.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8124"/>
    <dbReference type="EnsemblBacteria" id="ACU76947">
        <property type="protein sequence ID" value="ACU76947"/>
        <property type="gene ID" value="Caci_8124"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8124"/>
    <dbReference type="eggNOG" id="COG1977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_1_0_11"/>
    <dbReference type="OMA" id="IRVMLPA"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="9512" checksum="6314CBDD1DD0DDA5" modified="2009-10-13" version="1">MSITVRIPTILRTYTDGKAEVSVAGGTLAEVIDQLEADHTGIRARVLDDDGKLRRFVNVYVNDDDVRFAEGLGTAVPAGGSVSIIPAVAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ2</accession>
    <name>C7QIZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8219</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796767.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8219"/>
    <dbReference type="EnsemblBacteria" id="ACU77042">
        <property type="protein sequence ID" value="ACU77042"/>
        <property type="gene ID" value="Caci_8219"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8219"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WARRTAY"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="112"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="20294" checksum="EE4A32D5D79E5593" modified="2009-10-13" version="1">MRSLRNGTSPEHHEEFRAFVTGSQGHLRRSAYVLCGDWHLAEDLVQNAYQRIFRLWHRVRLMDLPDAYARRVVYRCFLDSRKWRREAASLEALVDRPAVQDDAAVRLTILAALAELAPRTRAVVALRYWEDQSVEQTAEALSISTGTVKSMSARGLAQLRERLGDFAALLPDSVDTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ05</accession>
    <name>C7QJ05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0192"/>
    <dbReference type="EnsemblBacteria" id="ACU69147">
        <property type="protein sequence ID" value="ACU69147"/>
        <property type="gene ID" value="Caci_0192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0192"/>
    <dbReference type="eggNOG" id="ENOG5032Y5U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082059_2_0_11"/>
    <dbReference type="OMA" id="PVDTMVW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="25087" checksum="5BAC7ECBEDDB23ED" modified="2009-10-13" version="1">MTAMTAHTHRTADVTADGAGVADVADGETPHPLKQALLPLAVDIAIPLGSYYALHAGLGMSNAAALGLSSVVPAIRTIVAAVGKRQANALAALMLTVNIVAIALTFVSGDARLMLAKDSGVSSVIALGILWSVRGGKPMMSAGLKPFVTKGDAKQTAAWDALRIESSTFRAKENLYSVIWGAWLLTECLARLAGAFLLPVSTMAWLGTVILIVAIAGACVTGGAAVEPLEKLVAAHVEAASDAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU2</accession>
    <name>C7QJU2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792909.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4316"/>
    <dbReference type="CAZy" id="GH79">
        <property type="family name" value="Glycoside Hydrolase Family 79"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73180">
        <property type="protein sequence ID" value="ACU73180"/>
        <property type="gene ID" value="Caci_4316"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4316"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033984_0_0_11"/>
    <dbReference type="OMA" id="ALWIIDY"/>
    <dbReference type="OrthoDB" id="1303824at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983272" evidence="1">
        <location>
            <begin position="34"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_79C" evidence="2">
        <location>
            <begin position="384"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="485" mass="49124" checksum="FEC6B1B55AF4A18D" modified="2009-10-13" version="1" precursor="true">MKTVTRTRAAVAAATLAAASLAAALTGSGTAQAAGGPAQPAAAGLAIAVHPDQVGQQLRAGFVGLSFGAATVAADDYSATDLAGYLKTLGPSGTLRVGGNSGDGTFWTSTNEAAPSWATSGTITPAKLQSLAAIAHATGWKVILAVNLKHPDAPRAADEAKYAQQIFGRSLLAIEVGNEPNFYEADADAYHADFETYAAAIRAAVPGMPLTGPEAETNHSSWLGAFATADAAHPDVSLISDHTYPTSACGGQVATIPQLLGTASVQYENTNAQAALSAARQLHVPAAMTETNSTVCAGTAGVSDTLASALWSLDYNLLLAQDGMTSAEFMDGTNAAGCDPYTPLCPTTGDLTPRPLYYGLLATELVGSGEFVALDNPDSADIRAYAVRESGHLTIVLDNVQDPASHGATTVNLALGLRNLHCGTATTLSTTSPAGLAATTDITLGGQQVGAHGAFPTPQHTSVSVRHGAANVTVQAGSAVIIRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJV1</accession>
    <name>C7QJV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4325"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73189">
        <property type="protein sequence ID" value="ACU73189"/>
        <property type="gene ID" value="Caci_4325"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4325"/>
    <dbReference type="eggNOG" id="COG1361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_13_0_11"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018905">
        <property type="entry name" value="A-galactase_NEW3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003343">
        <property type="entry name" value="Big_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="PTHR42721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02368">
        <property type="entry name" value="Big_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10633">
        <property type="entry name" value="NPCBM_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00635">
        <property type="entry name" value="BID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981051" evidence="3">
        <location>
            <begin position="34"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="5">
        <location>
            <begin position="719"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="BIG2" evidence="4">
        <location>
            <begin position="832"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1343" mass="138765" checksum="1EE60D6E11A8BA2F" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK46</accession>
    <name>C7QK46_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6266"/>
    <dbReference type="EnsemblBacteria" id="ACU75120">
        <property type="protein sequence ID" value="ACU75120"/>
        <property type="gene ID" value="Caci_6266"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6266"/>
    <dbReference type="eggNOG" id="COG2315">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105851_1_1_11"/>
    <dbReference type="OMA" id="NKRHWNT"/>
    <dbReference type="OrthoDB" id="1817663at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35145">
        <property type="entry name" value="PTHR35145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="117" mass="12747" checksum="0AF054A160B6C6C9" modified="2009-10-13" version="1">MTPEELKAACLDHHGAVEDFPFAPEVSVFKVAGKVFAITRLDEHPLAVSLKSDPDLAANLRAAHAAIRPGYHLNKRHWNTVTIDGSLGEEMVLDMIEDSYDLVVKSLTRAQRAALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKG9</accession>
    <name>C7QKG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796793.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8245"/>
    <dbReference type="EnsemblBacteria" id="ACU77068">
        <property type="protein sequence ID" value="ACU77068"/>
        <property type="gene ID" value="Caci_8245"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8245"/>
    <dbReference type="eggNOG" id="ENOG5032Y6I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154652_1_0_11"/>
    <dbReference type="OMA" id="MCTAPKQ"/>
    <dbReference type="OrthoDB" id="1774182at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010814">
        <property type="entry name" value="DUF1416"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07210">
        <property type="entry name" value="DUF1416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="9873" checksum="F653405F0DDA8032" modified="2009-10-13" version="1">MTASCGAPAGGFSIEGVDVAKETVIQGAVSRDGAPVTGYVRLLDSTGEFTAEVPTSPEGGFRFFAAPGTWTVRALVPGGTVDASVEATLGEVAEVALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKJ4</accession>
    <name>C7QKJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8270"/>
    <dbReference type="EnsemblBacteria" id="ACU77093">
        <property type="protein sequence ID" value="ACU77093"/>
        <property type="gene ID" value="Caci_8270"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8270"/>
    <dbReference type="eggNOG" id="COG1322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024057_1_1_11"/>
    <dbReference type="OMA" id="GDSKMQG"/>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="39671" checksum="645829D137DA311F" modified="2009-10-13" version="1">MPVLLLVIGIAFGALLGVLWERSRRLAVSSEALDQSADRLLALAGSQFDAAGRPINESLSRLDDRLRDIEKGRAASQAALAQQIDDVRSAAGALGTQTAALVTALRRPEVRGQWGEMHLRRAVELAGMVDRCDFTTQTVIPGSYGATGSEGMLRPDLVVHLAGDKYVVVDAKTPLAAYLDAAEATDDAERRQYLTAHAKHLRAHVDQLASKAYWRALGASGRPTPEFVVLFVPGEAFLSQAVDIDPDLMEHAAARRVVLATPTTLIALLRTVAYAWTQDSLAANARQVFDLGRELYARLNTMNGHLDRVGKGLNSAVAAYNQSVGSLETRVMVTARRLNELGLVDEELVVPNQVEIQTRALSDQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM7</accession>
    <name>C7QKM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8303"/>
    <dbReference type="EnsemblBacteria" id="ACU77126">
        <property type="protein sequence ID" value="ACU77126"/>
        <property type="gene ID" value="Caci_8303"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8303"/>
    <dbReference type="HOGENOM" id="CLU_2988190_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="57" mass="6470" checksum="B7A870589FFF5761" modified="2009-10-13" version="1">MNNTVFTLEIANARRAELIEQARRHGLAKRARRAQDICPEKVHTVHVGSRSGERSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ1</accession>
    <name>C7PVJ1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784642.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0395"/>
    <dbReference type="EnsemblBacteria" id="ACU69347">
        <property type="protein sequence ID" value="ACU69347"/>
        <property type="gene ID" value="Caci_0395"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0395"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_1_0_11"/>
    <dbReference type="OMA" id="IHITEAM"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="56"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="22392" checksum="3FFE4C18F01973F3" modified="2009-10-13" version="1">MQKFETPSPVTVVLDIPAGQIRLVAGERADTVVEVLPSEASKRRDAKAAAQTTVEFSGGVLRIATADPHKILGSSGSLDVTIALPAGSRIEGKAGAAELHSTGRLGEVAFDGGYRSVELDEVAGARIKMHMGDVSIAKLTGPAQLRNGKGDITVAEAAGGAVDLRTDMGDLKIAAAPGVSGTLDASSASGRITNALKNSEGAGAGLNIKATTSHGDIIATSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVV7</accession>
    <name>C7PVV7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786642.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2431"/>
    <dbReference type="EnsemblBacteria" id="ACU71349">
        <property type="protein sequence ID" value="ACU71349"/>
        <property type="gene ID" value="Caci_2431"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2431"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_0_0_11"/>
    <dbReference type="OMA" id="SVIWRVF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="21901" checksum="E420474549D184F1" modified="2009-10-13" version="1" precursor="true">MPVASFAALLTVWTLALLIPGPDFLAVSHASVARSRRDAVFVGLGVAAAMAVWATTSLVGLTVLLVRFQPVFEAVRVAGAAYLLWLAFQLLRSAARRKVHGPAAGATGVRPRGAVSAFRAGFLCNIGNPKAAVFFSSVFAALLPPHVDWEYRTAIGVAIPAIGVAWYALVACLFSAKRIAAAYARARRVVDAVTGTLFAVLAGDLLIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVY3</accession>
    <name>C7PVY3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septum_form domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2457"/>
    <dbReference type="EnsemblBacteria" id="ACU71375">
        <property type="protein sequence ID" value="ACU71375"/>
        <property type="gene ID" value="Caci_2457"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2457"/>
    <dbReference type="HOGENOM" id="CLU_1140958_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026004">
        <property type="entry name" value="Septum_form"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13845">
        <property type="entry name" value="Septum_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Septum_form" evidence="3">
        <location>
            <begin position="108"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25727" checksum="0AF11CDCED412CD2" modified="2009-10-13" version="1">MTEPQSSQSPYQGISGPGGNYAPTQDQMPYAAQNPYGQQQPQYGQGAPQNPYAQAPQNPYGNGNGTSNAGFGYGPPPKRRRGQTLVYVRLGIFVVVLIAGGISWMVTNSHKSHRDATGTISKGGNLDAVSLRAGDCYERPADASVAFDSVKAIPCTQPHNAQAFYSFTYPGATSVAPTDDDLTANAQPLCENAAKTKVDQSKLPQSAEASMLFADGSTWSQGYHDITCVYENDADYTGSILAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWB0</accession>
    <name>C7PWB0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="5">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793087.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4495"/>
    <dbReference type="EnsemblBacteria" id="ACU73358">
        <property type="protein sequence ID" value="ACU73358"/>
        <property type="gene ID" value="Caci_4495"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4495"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_0_2_11"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="31685" checksum="2C694B10BFEF410B" modified="2009-10-13" version="1">MPLPRPATLGAIRVAREAATLIRRSAAPRRLRFKTSSADLVTATDLRVERLVRAWLKATHPEHAVVGEEGGGLAEMDLSRPTWFVDPVDGTTNFVRGIPHCACSLAFWDGQRIALGVVADVARRRIYWAEAGRGAYEGRRRLRASPVRRLDRAVLATGFPPTRSFDSDDNLAEFSSVFRQSRDVRRTGSAAIDLAWVAAGRLDCYWEQRCGPWDWAAGVLLVREAGGKATTYAGLEWHPGDADLVASNGPVHPALVESFCEARAAAGFPARPPQPSFAPAQPVQPAPSGASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWB4</accession>
    <name>C7PWB4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4499"/>
    <dbReference type="EnsemblBacteria" id="ACU73362">
        <property type="protein sequence ID" value="ACU73362"/>
        <property type="gene ID" value="Caci_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4499"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_31_0_11"/>
    <dbReference type="OMA" id="EITYWID"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="17331" checksum="6A1A9645DBE77370" modified="2009-10-13" version="1">MNETVLRQMRESDLPALFEIQCDAEAQVMAAFTSTANDRQAYLDKHRKLLADDRIVQVVVEADGEIVGSAAAFPLGEEIDVTYWIRRDHWGRGLAGAALAAVLEQVPVRPVFASAASDNLASQRVLERAGFRQVGRQRGFAEARGQEIEEVMFRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWB8</accession>
    <name>C7PWB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73366">
        <property type="protein sequence ID" value="ACU73366"/>
        <property type="gene ID" value="Caci_4503"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4503"/>
    <dbReference type="eggNOG" id="ENOG5034B56">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544848_0_0_11"/>
    <dbReference type="OMA" id="ACSEQRC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982247" evidence="1">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="17666" checksum="20D5C9D21480A1B5" modified="2009-10-13" version="1" precursor="true">MRSSTALVVAALSGVPVLAALAFAGAVHRHPHAVGFTDQGVSVAMHLTGDGSELLTTFTPQRPGFHLYSVGLPADGIQGLGRPTRVEVGGALRSRGPLTAQSPVRMLAMQGTDVTFPVYPDGPVTTALPVDLDAKGGAKVLVSYAACSPQECLMPVSGHPVELTASALSAMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWM0</accession>
    <name>C7PWM0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795029.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6448"/>
    <dbReference type="ESTHER" id="catad-c7pwm0">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75300">
        <property type="protein sequence ID" value="ACU75300"/>
        <property type="gene ID" value="Caci_6448"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6448"/>
    <dbReference type="eggNOG" id="ENOG5033TX8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089595_0_0_11"/>
    <dbReference type="OMA" id="GCGHAAH"/>
    <dbReference type="OrthoDB" id="1705680at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="22284" checksum="4160E07A4ACA8535" modified="2009-10-13" version="1">MLIGVPAPRVVLIHGAATTAAVWNPVREALSRTRPDIRVAAPQRAYSGDLDLELAALAETAAGAVVIGVSGGATLGLALMASGVPLAGAVLHEPAVGSLVPGLLAHVAAGYQARGVPGFGAALYGPAWDASMAPADPEAVGRDFAMFRAFEPAVPATVPALGRTSTTVGELSPPARHEAARALSTFTGLPFQVLEGCGHAVHLERPLLFAAVIGRAVGAEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR1</accession>
    <name>C7PWR1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795070.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6491"/>
    <dbReference type="EnsemblBacteria" id="ACU75341">
        <property type="protein sequence ID" value="ACU75341"/>
        <property type="gene ID" value="Caci_6491"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6491"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_5_0_11"/>
    <dbReference type="OMA" id="GWVSGFT"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="34525" checksum="2B1E76851F24FD31" modified="2009-10-13" version="1">MHLGVNLLHHGAVPLARAAEDAGYRIVLAPEGYRSDAPSVLGAVAGATDGILLASGVMQIPARPAILTALTAMTLHTLSGGRFRLGLGVSNPDISESWYGVPFDRPLSRTAQYVRVVRAAISGEGMAAATDPERTDGTGAVRLPLAPAAPGAVPVYLAAGGPGNLRLTGRVADGWIGMFSSPEQTTASIAAIDAGAAAADRDIAGFDYLVCAPAFVHDDPALAADRLRGHYAHLLTVGGPGRNIYVRLARGMGYGAELDALYKYVAAGDRVAAAKAVPQGFIDATALIGPPSRIAERLAAYREAGATTVSAMVSSADADTTERIATIRAIGKAWHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWS2</accession>
    <name>C7PWS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase domain protein TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796904.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8356"/>
    <dbReference type="EnsemblBacteria" id="ACU77179">
        <property type="protein sequence ID" value="ACU77179"/>
        <property type="gene ID" value="Caci_8356"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8356"/>
    <dbReference type="eggNOG" id="COG1082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065571_0_0_11"/>
    <dbReference type="OMA" id="EVMVWTD"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="35"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="193"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="34809" checksum="1C0BBC7A7ECD3E28" modified="2009-10-13" version="1">MTFRTDSTGTTEQVTTPKVGLSTSSVYPEPTRYAFDLANRLGYDGVEVMVSVDPASQYPDKILEYVEEYQVPVLSIHAPTLFWLNLKRVWGSDPWEKLKKSREAAERVGAKVVVVHPPFRWQQPYAEEFAEGIRRLNQESEVRFAVENMYPWRASTPDIFGRIPRIKVPRMEREGEAYFPGWDPTEKGYEHYVLDLSHTATARNDALAMYDRMGDKLVHLHLADGSGQNKDEHLVPGRGSQPCQEVLERIARRGLAGAVVLEVSTRRAETDLQREEDLRESLVFARRALARVHDEAEQRALPVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA3</accession>
    <name>C7PXA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784749.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0507"/>
    <dbReference type="EnsemblBacteria" id="ACU69454">
        <property type="protein sequence ID" value="ACU69454"/>
        <property type="gene ID" value="Caci_0507"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0507"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454698_0_0_11"/>
    <dbReference type="OrthoDB" id="146961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982280" evidence="2">
        <location>
            <begin position="30"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="3">
        <location>
            <begin position="181"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="600" mass="61064" checksum="42AFEBE10F6A5952" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXE9</accession>
    <name>C7PXE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784795.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69500">
        <property type="protein sequence ID" value="ACU69500"/>
        <property type="gene ID" value="Caci_0563"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0563"/>
    <dbReference type="HOGENOM" id="CLU_2599568_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8763" checksum="43E22722FFE0CDF8" modified="2009-10-13" version="1">MRTTQESENWAVEFIRTDGENQSLSVEDGFSTRGDAEYYGQCTWSSPGGRGIEQVRVRQLPRGPWMPVAPASVCGGIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI2</accession>
    <name>C7PXI2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Beta-glucosidase</fullName>
            <ecNumber evidence="3 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_2517</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786728.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2517"/>
    <dbReference type="CAZy" id="GH1">
        <property type="family name" value="Glycoside Hydrolase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71435">
        <property type="protein sequence ID" value="ACU71435"/>
        <property type="gene ID" value="Caci_2517"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2517"/>
    <dbReference type="eggNOG" id="COG2723">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_3_11"/>
    <dbReference type="OMA" id="NYYQTIT"/>
    <dbReference type="OrthoDB" id="654705at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="418"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="51192" checksum="3A79F59F99480F68" modified="2009-10-13" version="1">MSLELPRDFRWGVATSAYQIEGAVGEDGRTPSIWDTFCRVPGAIDNGEDGDVACDHYHRMPEDVGLIKSLGVDTYRFSVSWPRVQPGGSGPANAAGLAFYDRLVDELHSAGITPWLTLYHWDLPQELEDAGGWPNRDTAYRFADYAEIVYDRLGDRVEHWTTLNEAWCSAWLGYVEGVHAPGRKDFADGVASIHHLLLGHGLATQRLRAAAAAAERPIDLAITHILGNSVPASDSEVDVEAARRGDALHFRAYMDPIFKGAYPEDLLADLAAIDVPIPVQDGDLEIIAAPLDTLGVNYYRSMKTTGFGEDGGTTDADGRPVTRTIDFGGLPKTYIDWEVMPEDFADLLVRISEDYPGTPLVITENGAAYNDVPDADGFVDDQDRTDYIATHLAAVAQARQRGADIRGYFAWSLMDNFEWAYGYDKRFGIIRTDYQTQTRTPKRSALWLRDTIARARRPRGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL1</accession>
    <name>C7PXL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2546"/>
    <dbReference type="CAZy" id="GT20">
        <property type="family name" value="Glycosyltransferase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71464">
        <property type="protein sequence ID" value="ACU71464"/>
        <property type="gene ID" value="Caci_2546"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2546"/>
    <dbReference type="eggNOG" id="COG0380">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_7_1_11"/>
    <dbReference type="OMA" id="YYGFSNR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="PTHR10788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="498" mass="55805" checksum="37805A1140B95A0B" modified="2009-10-13" version="1">MGGTTRRGADFLVVANRLPVDLERLDDGTERWRPSPGGLVSALEPFLRSRRAAWVGWSGRADRDLEPFDDDGLQMHPVRLSSAEVRDYYEGFSNGTLWPLYHDVVVPPVFERSWWDSYVEVNQRFADAAAKVAGEGATVWVQDYQLQLVPAMLREQRPDLHIGFFLHIPFPPVELFMQLPWRKEVVRGLLGADVVGFQMPGGAQNFLWLTRQLLGLEPTRAAVRVRSRPGSVPFDGRQVRVGAFPISIDAASFDKLARQPETVERAKEMRSAMGDPQHLLLGVDRLDYTKGIDVRLRALRELLVSGRVDRESVAMVQLATPSRERVDQYKAMRRSIEEQVGRLNGEFGRVGRPIVHYLHQPMDRDELVALYSAADVMVVTPLRDGMNLVCKEYVATRRGLDGVLVLSEFAGAASELTGALLVNPHDLDGVAEALERALTMDPMEKRGRMRTLHRQVMTHDVGRWAKSFLDFLDPATAAAAAAEMANGAEAEQHRTSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY8</accession>
    <name>C7PXY8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793177.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4586"/>
    <dbReference type="EnsemblBacteria" id="ACU73448">
        <property type="protein sequence ID" value="ACU73448"/>
        <property type="gene ID" value="Caci_4586"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4586"/>
    <dbReference type="eggNOG" id="COG1503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044180_0_0_11"/>
    <dbReference type="OMA" id="GEHQVWS"/>
    <dbReference type="OrthoDB" id="1727546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041289">
        <property type="entry name" value="Bact_RF_family3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18845">
        <property type="entry name" value="baeRF_family3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="42499" checksum="D047DEDEB602B6C3" modified="2009-10-13" version="1">MDISELTPETLATLRSPRPYPAVTMVMPVDPKAPFSEKDRILLRGLCTEAQRQLAEDAEVEREVRLALRDGKLSPEAVAELVDPGVPAGELVVYVSAANPTQVWQVPTDAEVLPRVEFADRYLTRYLAAAEQRSWPYLVLVLDQEMCRLYRGAASRLREVKEHGFPDAPAIPSPEDAVPGPIPRAQPYEAHEEYVKQYLRTVDKNLGRALKAHDGLPLFVIGGDKILAAFLDLTGHHDVVAGTLPLTGMDKDTPSDLAKRVAPAVEAYRAEQVAAAVTELQDARSQNKYAGGPAEVWTATADKRVQRLLVEEGLLIAGRIGGDGRDLATVPYPEPVTLPQPKEDFEPPEPGVDTDIVEQLVENAVESGAQILFVPDGTLADAAGVAAALRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY99</accession>
    <name>C7PY99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795118.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6541"/>
    <dbReference type="ESTHER" id="catad-c7py99">
        <property type="family name" value="Haloacetate_dehalogenase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75389">
        <property type="protein sequence ID" value="ACU75389"/>
        <property type="gene ID" value="Caci_6541"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6541"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_11"/>
    <dbReference type="OMA" id="RGARICH"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="32693" checksum="B56DCC272B00468C" modified="2009-10-13" version="1">MFEDFETEVVQTGQASIFVRYGGEGPPVLLLHGHPRTSATWYEVAPAMVRRGYRVVCADLRGYGRSRGPAPTADHTAHCKRAVADDLVAVMRHLGLDHEGFALAGHDRGGAVALRLVLDYPELVRRVAFLDCLPISEHLNRISARFATAWWHWFFFAQPDIPERVITADPDRWYQGDPAQMGVENHREWREAVRDPDVVRAMLEDYRAGLTVDRRDEEADRAAGNRVRCPALVLWSLRDDLEDLYGDPLRIWRDWADDVRGHGIDSGHHMAEQASDELTAALDSFMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYV7</accession>
    <name>C7PYV7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784808.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0576"/>
    <dbReference type="EnsemblBacteria" id="ACU69513">
        <property type="protein sequence ID" value="ACU69513"/>
        <property type="gene ID" value="Caci_0576"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0576"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1109839_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27037" checksum="4A894B73CDEEDF7D" modified="2009-10-13" version="1">MSFNEYDGAPGGTGARRPERLSAEQIDAWEFPRAGLAHRGFDEEGVLRFKRRVLGELQAAAQIETELRQRNDELTNQLRTTYAGSDPANGGAAAAPAAPSSFAPEQRVTAAAVNAIAMAQRQAEEQIRAAEEYVRNVTEYARNQYTVTVNEGHRQGLLAAESAFQRRSEQLSTSLHSLEQQLEFLKAFGVAFGVQVEGALEKAREEVHVMIKNIHQAFDALNRNPPQSAGAPPVMGMAGLHAGSALPGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ48</accession>
    <name>C7PZ48_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ordered locus">Caci_0668</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784899.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0668"/>
    <dbReference type="EnsemblBacteria" id="ACU69604">
        <property type="protein sequence ID" value="ACU69604"/>
        <property type="gene ID" value="Caci_0668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0668"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_0_0_11"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="OrthoDB" id="1536415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="10"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="86"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="164" mass="17863" checksum="3F99F71468DE2141" modified="2009-10-13" version="1">MTQTNDSVTWLTQDAYDRLTAELQQLSGPGRVEIAQKIEAAREEGDLRENGGYHAAKEEQGKIELRIRQLTQLLEHAKVGDSVESGVAVPGAVVTIAFDGDEDDTLTFLLGSREDAADNMEVYSAQSPLGGAINGKKIGEQAEYELPNGKPMMVKLLDAKPYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ75</accession>
    <name>C7PZ75_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786825.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2615"/>
    <dbReference type="EnsemblBacteria" id="ACU71532">
        <property type="protein sequence ID" value="ACU71532"/>
        <property type="gene ID" value="Caci_2615"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2615"/>
    <dbReference type="eggNOG" id="ENOG50336KR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173250_0_0_11"/>
    <dbReference type="OMA" id="HPAPRID"/>
    <dbReference type="OrthoDB" id="1953476at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="8301" checksum="4A3C5C1231BF041D" modified="2009-10-13" version="1">MKGDRVEIVVDVGDGSRNYEIVATRAGRRVEVHIARGVVEVTEVTRTGVAVRTARFMAGRVLALVEHPVEGGQSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ77</accession>
    <name>C7PZ77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2617</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786827.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71534">
        <property type="protein sequence ID" value="ACU71534"/>
        <property type="gene ID" value="Caci_2617"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2617"/>
    <dbReference type="eggNOG" id="COG3237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182085_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10223" checksum="87C724A449A7B0BA" modified="2009-10-13" version="1">MSVGSKIKYAAQNARGKAKAAAGGATGNRRLRAEGRRDQGAAHVKHAADKAMDTAKNVGHEAKGKIRQVAGAVTDHKGQEAKGKAEQVSARGKEHLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZB1</accession>
    <name>C7PZB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71568">
        <property type="protein sequence ID" value="ACU71568"/>
        <property type="gene ID" value="Caci_2652"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2652"/>
    <dbReference type="HOGENOM" id="CLU_3326171_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="38" mass="3767" checksum="0955612DBBDEBEDE" modified="2009-10-13" version="1">MQGEAAEFARPQRMGIGIGIGSGSASDAAMRGESGELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC0</accession>
    <name>C7PZC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786870.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71577">
        <property type="protein sequence ID" value="ACU71577"/>
        <property type="gene ID" value="Caci_2661"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2661"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044190_1_1_11"/>
    <dbReference type="OMA" id="RTVREWE"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="203"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36404" checksum="215273AF1BAC9D37" modified="2009-10-13" version="1">MALATANSVLSLQDQRLIAVLQHDARVTAEKAAAVLDLSPAVVRRRWQAMCADGTLRVVISPIARPRTGGLTGAQLLHIRVRRDKIDAVARSLAARDDVPFVDITTAGDEIEAIAATRPGSRDPLVFHLLPSTPAVVSVEAATILHVLRVTSEWRHQVLGAEEVSALTLAEPQSGIGIGTGTGIGNGTATGLAPDGPYGIETDAQERAIIDVLTPDARLPAVAVAARTGLPESTVRRRISRLTDEGRLITQVLVDPRRLGLNLDARLKLRVTPDHLDRAARALAAHPAVHGAFATSGPSNLSLHVWFPDPAALYDFLARDVTGLGIASVETTLVAHWIKRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC8</accession>
    <name>C7PZC8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2669"/>
    <dbReference type="EnsemblBacteria" id="ACU71585">
        <property type="protein sequence ID" value="ACU71585"/>
        <property type="gene ID" value="Caci_2669"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2669"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_3_11"/>
    <dbReference type="OMA" id="KWTSMAV"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14287" checksum="334AD24B3BF6B2CD" modified="2009-10-13" version="1">MEVTALSDNTRGDLFDPACPTRALLDRVGSKWTSMAVKLLAEAAPQEIRFAELRRRMPGVSQKMLATTLRALVRDGLAQRRVEPTVPPRVHYSLTPLGLSLDGPLAVLRAWAEEHMAEIDRANRDADAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZD7</accession>
    <name>C7PZD7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786887.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2678"/>
    <dbReference type="EnsemblBacteria" id="ACU71594">
        <property type="protein sequence ID" value="ACU71594"/>
        <property type="gene ID" value="Caci_2678"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2678"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="STQMFPG"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31520" checksum="922C44CBC8F40021" modified="2009-10-13" version="1">MSDAVKHRSPTAPPRSFIWTRRIALTLLGLFTGIPLWVMVSSSVKSLVEVQNAFHWLPTHLTLSPYIDMWSTVPLGHYFLNSAIVASCSTAVSVVIAVFAAYAVSRYRFAGRKVFSVTVLSTQMFPGILFLLPLYLIFVNIGNSTGIQLSDTRLGLIITFLTFTLPFSIWMLVGYFDSIPRDLDEAASVDGSGPISTLFKILVPAALPGIVTVAVYSFMTAWGEVLFASVMTDDSTRTLAVGLRDYASQNDVYWNQIMAASLVVSIPVVAGFLLMQKYLIAGLTAGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI4</accession>
    <name>C7PZI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786934.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2726"/>
    <dbReference type="EnsemblBacteria" id="ACU71641">
        <property type="protein sequence ID" value="ACU71641"/>
        <property type="gene ID" value="Caci_2726"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2726"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="PNRWRAL"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="23"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="500" mass="51899" checksum="F2D5B5E0B3B2E3C4" modified="2009-10-13" version="1">MTQSYERAAPPDDGPADPNRWRALTVCLVAGFMTLLDVSIVNVGLPQMEAGLRASPADVSWVRAGYTLTFGLVLVPSGKLGDALGRKRVFLLGLFLFTGVSLMCALSPTAQWLVVARLLQGVAGGLLNPQIIAMIQQLFRGSERGKAFGLYGGTVAVATAIGPLAGGLLIEAGGWRWMFLINLPIGVVGLVLGVLLVPKIPPRRRGRGMDLVGVALLGGGITSIMLPLIEQEQGGAAVHWWLLGLAAVLLVAFVFWERWWKGRGLDPLVNLSLLRTPSFGASSLVGLAYFAGYPGVLFILSLYLQQGRAYSALAAGATSMPFAVGSAISAAVSGRAVYRIGRVLVVAGLVAVLAGLIPAAVIIQHDTGGAVWARLFLPLLVAGLGSGLVIGPNQTLALQFVPPASSGTAAAMVQTGQRIGMSVGTAMAATMFFGHLKVLRHDYSGAASRSLYGAAALVTVALAAASVDLAAARRLRRRPATGQAAEVPGSRTGSAVVKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT0</accession>
    <name>C7PZT0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxydechloroatrazine ethylaminohydrolase</fullName>
            <ecNumber evidence="2">3.5.4.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.4.43" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793324.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4734"/>
    <dbReference type="EnsemblBacteria" id="ACU73595">
        <property type="protein sequence ID" value="ACU73595"/>
        <property type="gene ID" value="Caci_4734"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4734"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_3_11"/>
    <dbReference type="OMA" id="ALIGKVC"/>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018763">
        <property type="term" value="F:hydroxydechloroatrazine ethylaminohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="58"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="455" mass="47687" checksum="B091E731A3625BEC" modified="2009-10-13" version="1">MSTIVIQNAAIATVDAASTEHATGHVVIEDGRITAVGSGPAPRDIEGARVVDGTGCLATPGLVNTHHHLYQWITRGLAQDAALFGWLVELYPIWARLTEDTLGAAARGGLAWLAKTGCTTSADHHYVFPRDGGDLLGAEIEAAREIGLRFQPTRGSMDRGRSDGGLPPDEVVERLDDILAASQDAITRYHDPSFDSMLRIGLAPCSPFSVSSDLMVQSASLAREHGVRLHTHLAETLDEEKFCLETHGCTPAEYADKLGWLGPDVWLAHCVHLSDAAIRRFADTQTGTAHCASSNARLGSGHARIKDLLAAGAPVGLGVDGAASQESGMLVEELRQAMYVSRLRALSSDPAEALNARAALRLGTAGGARVLGREAEIGSLEVGKLGDVALWDLTGLGHAGIADPVAALVFGPPAPLRLLAVGGRPVVEDGALTTADEDALARACRTAARSLTEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZW2</accession>
    <name>C7PZW2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PEBP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0098 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793356.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4766"/>
    <dbReference type="EnsemblBacteria" id="ACU73627">
        <property type="protein sequence ID" value="ACU73627"/>
        <property type="gene ID" value="Caci_4766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4766"/>
    <dbReference type="eggNOG" id="COG1881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083918_2_1_11"/>
    <dbReference type="OMA" id="LAWDEVP"/>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19249" checksum="63CA49FA8AFA3EE6" modified="2009-10-13" version="1">MRVSSPYDTSEQVPSFDVASSEFKAGERLAPEHGSAIFEVPGGREISPQLSWGPVPEGTKSISVTMFDPDAPIPSGFWHWGLADLPADTAELPAGAGAGDDSLPGGAFHVPNELGMHQYVGFGPPPGTGRHRYYFAVHALDVDSVRDLGVTPETTPAVLHFMMRGHELARGVLQGWASADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZX0</accession>
    <name>C7PZX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate--cysteine ligase GCS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793364.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4774"/>
    <dbReference type="EnsemblBacteria" id="ACU73635">
        <property type="protein sequence ID" value="ACU73635"/>
        <property type="gene ID" value="Caci_4774"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4774"/>
    <dbReference type="eggNOG" id="COG2170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029030_0_0_11"/>
    <dbReference type="OMA" id="CRRRVNG"/>
    <dbReference type="OrthoDB" id="367541at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016602">
        <property type="entry name" value="UCP012666"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012666">
        <property type="entry name" value="UCP012666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="495" mass="55692" checksum="D853378AE9A1BA3D" modified="2009-10-13" version="1">MGERVVATEFTGADRTRFRERLRAGFEVFRRMLAEDRFERGRTLMGVELELDLVDPFGRPVMVNQDVLSRIASRDFQTELGQFNLEVNIAPHKLVGTVFSELAEELRTSMAYADRQARAAGARILMIGILPTLDEAHMVVENFSAEDRYFLLNDEIAQVRGEDFLVEIDGVERLRTTFASIMPEACNTSVQFHLQVSPETFAPAWNAAQALAGVQVALGANSPFLFGRELWAETRIPLFEQATDFRVEELAAQGVRPRVWFGERWISSPLDLFEENLRYFTALLPVSSDEDPEKVLAEGGIPHLPELRLHNGTVYRWNRPVYDVARGKPHLRVENRVLPAGPTVVDVLANAAFFYGCVKALMEDPDPVWAHLSFEDAARNLHNAARHGLAAQLEWRRDEHEGSLPVRELVLTELLPAARRGLDALGIDPRDRDEFLGIIEGRCETGRNGSTWLSGRFHRLVGEEGLDRAAALERLTIEYADLMITGAPAHTWKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0C5</accession>
    <name>C7Q0C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797182.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8642"/>
    <dbReference type="EnsemblBacteria" id="ACU77458">
        <property type="protein sequence ID" value="ACU77458"/>
        <property type="gene ID" value="Caci_8642"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8642"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="SMLYNDF"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="3">
        <location>
            <begin position="5"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="41307" checksum="1AD462CDFD80F389" modified="2009-10-13" version="1">MTTEIQPFQIAIPQPDLDDLHARLTNARWAASVPGAGWERGVPVDYLKELAEYWRSGFDWRAQEKALNAYPQFVTEIDGQRIHFLHIRSARPDAKPLLITHGFPSSVAEFMTLIEPLVAPESDEDQAFHVIAPSLPGYGFSTPLAAQGWTLSRTARAWIELMRRLGYDRYGVHGGDVGSGVAGLVAGYAADHVTGVHVTTDPQTAANVATFLPGLADRLDATDPVDALALERMNAFRKEGSGYLAIQNSRPQTIGYGLVDSPILQLAWIAEKFELWTDLPIDRDQLLTTVSLFWFTGAGASAAHTLYDQFHSSDWGAPSPVPHGYAVFGADATVRKLVPAEQDAHWSEFERGQHFPAMECPDVLAADLRDFFGPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Z3</accession>
    <name>C7Q0Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786961.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2755"/>
    <dbReference type="EnsemblBacteria" id="ACU71668">
        <property type="protein sequence ID" value="ACU71668"/>
        <property type="gene ID" value="Caci_2755"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2755"/>
    <dbReference type="eggNOG" id="COG3358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093051_0_0_11"/>
    <dbReference type="OMA" id="NLPCAYT"/>
    <dbReference type="OrthoDB" id="1878942at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29449" checksum="CBE5FF69A06F596D" modified="2009-10-13" version="1">MTVQDVAADVDAFAQTWREWHSGHEDRLADPHGFLAVTSLHWLHEEPQRFPDAPGAWSTGPDGVRVVLAEGEELIVDGAAVHGEYSFGVIGERASLFPVSGDAVIEVAKRGGHDIVRPRHPENPLRLAYNGTPAYEPDSRWAVTGRYVAFDHPRPTTVGAAVEGLQHVYDAPGRVEFDLAGHSLSLTVFEGHAPGSLLALFTDATSGVSTYAANRSLQIDPPAADGTVWLDFNRAVNLPCAYTDLATCPLPPAENRLQVAVETGEKIPHERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q141</accession>
    <name>C7Q141_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787009.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2803"/>
    <dbReference type="EnsemblBacteria" id="ACU71716">
        <property type="protein sequence ID" value="ACU71716"/>
        <property type="gene ID" value="Caci_2803"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2803"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="EETWEVI"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="14"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="108"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="20152" checksum="83648FD464A8785C" modified="2009-10-13" version="1">MDAEQEQEFRAFVAARSRALTSTAYLLTGDAEQAADLVQSALAVTWVRWPKLKDRGRAEAYVRKTIYHAYVDRTRLFSWRRERSTAELPERADAGTDLAEAVARSHDVAALVRRLPRGQRAVTVLSYYEDRSDEEAAEVLGVSVSTVRTQRFKALRGLRVMIREEDRPAELAGREVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q168</accession>
    <name>C7Q168_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2834"/>
    <dbReference type="EnsemblBacteria" id="ACU71743">
        <property type="protein sequence ID" value="ACU71743"/>
        <property type="gene ID" value="Caci_2834"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2834"/>
    <dbReference type="HOGENOM" id="CLU_1465717_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19232" checksum="C36059FE443DCCFE" modified="2009-10-13" version="1">MPTFSAGQRLTAAELNADFPLISSTVLTGTTANMPLFVSSGFNRVQVFWRARGTAAVGAEQLWLQMNGDSGSHYLWQKTETENSTATSASSGGLTTQIQIATMMGANATANYYSSGNFTVDGISDGTGFSTTVGISAAFNTVSDSWSGRFSGQYNVSAIITSLLLFPNSGSFSAGSVFSVYGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S5</accession>
    <name>C7Q1S5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6 12">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_6784</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:43437"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6 12"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6784"/>
    <dbReference type="EnsemblBacteria" id="ACU75626">
        <property type="protein sequence ID" value="ACU75626"/>
        <property type="gene ID" value="Caci_6784"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6784"/>
    <dbReference type="eggNOG" id="COG1232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009629_3_1_11"/>
    <dbReference type="OMA" id="EHNQAVQ"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0274">FAD</keyword>
    <keyword evidence="8 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="13">
        <location>
            <begin position="31"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU75626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="49478" checksum="D0D5D6D7CD94DF83" modified="2009-10-13" version="1">MSAGQTSSQGSMSARGPGARPRSVAVIGAGVSGLAAAWYVKQALPDATVTVFEGSPRLGGKLALGEVGGVQVDLGAESILNRRPEAVDLARAVGLADDIVHPATASASVWSRGELVPMPKGHLMGVPGDPGVLAGLLSPAGLRRAEAGPALPSRSVLRVQAETDDIAVGAYVAETFGREVVDRLVEPLLGGVYAGHADEISLRAAVPALVPAYESGEPLDEAVSKILAAQSAAANPKPVFAGVRGGVGRFPAALTESCESAGVTIRRETMVRGLTRTADGWRLVSGPVPAPSAHEADAVIVAVPGAPASRLLKDVAPVAAADLAGIEYASVALATFVFDDASLPAGSGFLVPPADGRFIKASTFSSVKWSWLAESGKTVVRASVGRHRETADLHQEDADLAASALADLRIALGAPDALGEPVDWHVQRWGGGLPQYAVGHVARVERIRSAVAAQPGLAVCGAAYDGVGIAACVASALRAAREISAGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y7</accession>
    <name>C7Q1Y7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6847"/>
    <dbReference type="EnsemblBacteria" id="ACU75688">
        <property type="protein sequence ID" value="ACU75688"/>
        <property type="gene ID" value="Caci_6847"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6847"/>
    <dbReference type="eggNOG" id="COG3087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037208_0_0_11"/>
    <dbReference type="OMA" id="GIVGWIT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982435" evidence="3">
        <location>
            <begin position="32"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="60566" checksum="C35A7E475E07AFBF" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q246</accession>
    <name>C7Q246_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797307.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8768"/>
    <dbReference type="EnsemblBacteria" id="ACU77583">
        <property type="protein sequence ID" value="ACU77583"/>
        <property type="gene ID" value="Caci_8768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8768"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_3_0_11"/>
    <dbReference type="OMA" id="FRYHDTF"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="375" mass="41331" checksum="091A1913362A757C" modified="2009-10-13" version="1">MEFGIFVQGHVPLTQLAADPDFEHTSLMNDIAIAKAADKAGFKYVWASEHHFLDEYSHLASNDVFLGYLAAATERIHLGSGIFNPLPQANHPVKVAEKVATLDHLSNGRFEFGTGRGAGSREILGLGLPDTAITKEIWAEVVREIPKMWLQDSYSYEGKWFSMPERNVLPKPWKKPHPPMWYAAGNAPSYEMAARMGLGVLGFSVGSPADAEAAVAAYKKAVPAAEPVGAYVNDNVMVTSSAVCLADGKRARRAASTMGMGRLQSLVFRYHDTFPRPDWIPAWPEVLPEPTVEEVEWRLRNGYLICGDPDEVLAQIKRYEATGIDQLTFGLPIQLSLADTLETIELIGRYVIPKLDKDPVHRTTRFRSAAAALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2C8</accession>
    <name>C7Q2C8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0836</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785065.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0836"/>
    <dbReference type="EnsemblBacteria" id="ACU69770">
        <property type="protein sequence ID" value="ACU69770"/>
        <property type="gene ID" value="Caci_0836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0836"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_28_11"/>
    <dbReference type="OMA" id="RPRHKRY"/>
    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982722" description="Histidine kinase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="165"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="225"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="46806" checksum="FA06FBA05EA15DC0" modified="2009-10-13" version="1" precursor="true">MRRRLVSSTFLVVMMVVILLGVPLAVLEVRSVDTSTKSVLATESRMLAQTVSMLVSKASLDGTNSGPLSDYDTDLQHMIARTHDATIDVDGQSPIQINSALPPGAPAFSVTYEMDGVLRNVGVRVTVQAPRAPAEDQIRGSMYLIGGVALAVLVAATGLAYLQARRLTKPLEELAATAERLGSGDPRPRHRRYGISELDRVAEVIDSSADRISTMLGAERRLAAEASHELRTPLAALSMRLEEIITLADDPQTVRDEAEVALSQVERLTDVVQRLLTTVRTHRRSDLAVPIEVDTVIRQQVHEWRPAYQSMRRGIVVSGERRLMAMATPGAFSQILSTLLENSLIHGAGTVTVHTRAVGGSVVVEVGDEGDGIAPDLEAKLFERGASSRGSTGLGLAVARELAEADGGRLNLVLQRPAVFAVFLTEHSPLSVIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2D1</accession>
    <name>C7Q2D1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ordered locus">Caci_0840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0840"/>
    <dbReference type="EnsemblBacteria" id="ACU69773">
        <property type="protein sequence ID" value="ACU69773"/>
        <property type="gene ID" value="Caci_0840"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0840"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_2_11"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="103"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="40093" checksum="2E30445576BC0A81" modified="2009-10-13" version="1">MVGVVGGGQLARMMQQAAIGLGVELRVLAQRPDDPAARVTPGTVIGDHHDFEALKAFAAGCDVLTFDHEHVPTDFLHELEAAGVAVRPGPDALVYAQDKGLMRQRLSALGLPCPQWALISSADDLADFGATVGFPFVLKATRGGYDGRGVWVVDDLDAAKAVLDGAAERGVALLAEAKVPFVRELSAQVARSPHGQAAAYPVVESLQIDGICREVYVPAPGLSEVAAVEAQRIALTIAKELGVTGMLAVEMFETADGSVLINELAMRPHNSGHWSMDGAVTGQFEQHLRAVLDLPLGQVKPVAPVVVMANVLGLDLPEVYPAYKHVMAHDPGVKVHMYGKDVKPGRKIGHVNVLGTVFDDVADRARHAAAYLRGEIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2I2</accession>
    <name>C7Q2I2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785119.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0891"/>
    <dbReference type="EnsemblBacteria" id="ACU69824">
        <property type="protein sequence ID" value="ACU69824"/>
        <property type="gene ID" value="Caci_0891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0891"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_12_2_11"/>
    <dbReference type="OMA" id="LVYWSMW"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982456" evidence="1">
        <location>
            <begin position="29"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="46874" checksum="34E9DBE06436A7A0" modified="2009-10-13" version="1" precursor="true">MGSTTGRGPRLLAIATAAVLTVGVSACSSSKSSSSAVGGAGKSGGSFTYWSMWRQDEPQAKVIQAAITQFTADTGIKVDVEWTGRDVAKKIGPAMAAGKAPDMWDEGADVIYGATAQNGNAKDLSAVLDMTIPTDNEKVSDAIPSKYWDSLPKDPNGGQHWVIPYEASTAGIFYNTADPTVSAAMASQPSTWDAFMQVCATLKTKSEPCLASEGEDPWTNGLWFDYLINAGGVNFNDLANDKTGASWDNPAVLKAATQVEQLVKGGYIIPTYTATKYPAQQTNWAGGKAGFLMNGNWVTAEVAKQIPATWKYGFMLPPGATQPDSMVFGFALTKNAKNVSQAEQFMAYFLQKKTLSGISTEAGNITPRTDIPAPAELADVQKTLNAPKLRLTFDGVAGDWTTKVWNQNYLDFWHGKIDAATFVAKMKSAQVSFWKSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Q0</accession>
    <name>C7Q2Q0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787085.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2883"/>
    <dbReference type="EnsemblBacteria" id="ACU71792">
        <property type="protein sequence ID" value="ACU71792"/>
        <property type="gene ID" value="Caci_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2883"/>
    <dbReference type="HOGENOM" id="CLU_2394393_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="10227" checksum="16F60C15C9428FAB" modified="2009-10-13" version="1">MNGPQHYAAAEKALAKAESESGPRGDAGQLDKHMRLHAAHLAMAQFALDVAVNADRLFDGMEMRSEQLQARTDAMYDNRNNWIAAITEDRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V9</accession>
    <name>C7Q2V9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2942</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787144.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2942"/>
    <dbReference type="EnsemblBacteria" id="ACU71851">
        <property type="protein sequence ID" value="ACU71851"/>
        <property type="gene ID" value="Caci_2942"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2942"/>
    <dbReference type="HOGENOM" id="CLU_2750343_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="70" mass="7893" checksum="FD6CF3D20D730E95" modified="2009-10-13" version="1">MMMTPEQSAKLQAKAQPLMEMLVEVLNELSELNNAAGLNQIITGHNEILTAGGTVVYQPWTRRWEIGIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q313</accession>
    <name>C7Q313_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787198.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2996"/>
    <dbReference type="EnsemblBacteria" id="ACU71905">
        <property type="protein sequence ID" value="ACU71905"/>
        <property type="gene ID" value="Caci_2996"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2996"/>
    <dbReference type="HOGENOM" id="CLU_2714973_0_0_11"/>
    <dbReference type="OrthoDB" id="2092976at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="72" mass="8133" checksum="2504169FFB3C7CF3" modified="2009-10-13" version="1">MTTRKPPIKVVPGQIWADKDPRSAGRTVQILEVDGIRFAIVKSPSGLGRRSRVQYDERGLRGYRLVSEPKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q329</accession>
    <name>C7Q329_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the faeC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4905"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="ESTHER" id="catad-c7q329">
        <property type="family name" value="FaeC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73765">
        <property type="protein sequence ID" value="ACU73765"/>
        <property type="gene ID" value="Caci_4905"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4905"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_2_1_11"/>
    <dbReference type="OMA" id="TWIGHGG"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034429">
        <property type="entry name" value="FaeC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="entry name" value="PTHR38050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF1">
        <property type="entry name" value="PTHR38050:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982738" evidence="6">
        <location>
            <begin position="36"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="341"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="461" mass="47364" checksum="A6E3CE70CA972570" modified="2009-10-13" version="1" precursor="true">MQKRRAVFGPVALMALLVALVSALTVYGGLGAASASPGAAPAAASSGCGKAPVLASGSHTIQSSGQNRSYILRLPANYDSSHPYRLVFGFHWVGGTDNDVDSGGTDGYNWSYYGLRKLADADGNGTIFVAPQGINNGWANSGGQDVTFVDDMLSQFESGLCLDTSQVFSSGFSYGGSMTYALACARPAVFRAVAVYSGANLSGCAGGTQPVAYIGLHGIRDNTLPIANGRALRDTFVRNNKCTPQNPPEPAYGSLTHIVTAYSGCLPGYPVVWAAFDGAGHDPGPIDGSTGDGWHTWTSGVVWNFFTQFQNGQPPSSTPSTPPSTTPPGNGQGALHAIGAGKCLDDPNSATTTGTQLQIHDCTGQANQAWTHTSSGQLSVTVGGSTLCLDANGKGTTNGTKAILWSCNGQSNQQWTLNSNGTVTGAQSGLCLDVTGASSANGALVELWTCNGGSNQQWALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q351</accession>
    <name>C7Q351_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-arabinofuranosidase B catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4927"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH54">
        <property type="family name" value="Glycoside Hydrolase Family 54"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73787">
        <property type="protein sequence ID" value="ACU73787"/>
        <property type="gene ID" value="Caci_4927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4927"/>
    <dbReference type="eggNOG" id="COG3693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029332_2_0_11"/>
    <dbReference type="OMA" id="GTHYNAG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031221">
        <property type="term" value="P:arabinan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019566">
        <property type="term" value="P:arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="PTHR39447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982468" evidence="1">
        <location>
            <begin position="47"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="378"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="498" mass="50724" checksum="D0E8B0E9A0E791E9" modified="2009-10-13" version="1" precursor="true">MAHSARLSDSPPAHHRLRALTFLAAAVLLVAGALVTGMTNATPARAATQGPCDIYASGGTPCVAAHSTTRALYGSYSGNLYQVRRSSDNATSNIGVLSAGGFANAAAQDSFCAGTTCVITVIYDQSGRGNNLTQALGGGAAPGADNLAVATAAPVTLSGHKAYGVFIPAGTGYRDDSTNGIATGDQAEGEYAIFDGTHYNGGCCFDYGNAETNNNDDGNGTMEAIYFGNIRVWGYGSGNGPWIMADMENGLYSGQNAGYNANDPSISDRFTTAIIKGTANLWAIRGGNAQSGSLSTFYSGPRPNVSGYNPMRKQGAIILGTGGDNSRGSDGTFYEGVMTSGYPSDATENSVQANIVAAGYTTGGTGPSGGGLHAVGAGKCLDVPNASTTNGTQVQIYDCNGQSNQAFTHTSAGAITVTDAGVTDCLDANNKGTTNGTKVIIYPCNGQNNQQWTFNSNGTITGVQSGLCLDVTGASTANGALVELWTCNGGTNQQWTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q463</accession>
    <name>C7Q463_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0995"/>
    <dbReference type="EnsemblBacteria" id="ACU69923">
        <property type="protein sequence ID" value="ACU69923"/>
        <property type="gene ID" value="Caci_0995"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0995"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029834_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018674">
        <property type="entry name" value="DUF2142_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09913">
        <property type="entry name" value="DUF2142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="625" mass="66008" checksum="95F6DA496071E05B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q466</accession>
    <name>C7Q466_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785220.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0998"/>
    <dbReference type="EnsemblBacteria" id="ACU69926">
        <property type="protein sequence ID" value="ACU69926"/>
        <property type="gene ID" value="Caci_0998"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0998"/>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087829_1_0_11"/>
    <dbReference type="OMA" id="SVIVVEW"/>
    <dbReference type="OrthoDB" id="1827295at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19102" checksum="BAFE26EB37416313" modified="2009-10-13" version="1">MSVIPDQAGPGLPGPVLETPVATAGAMKDLGRRLGARLRRGDLVVLTGDLGAGKTTFTQGLGEGLGVRGPVTSPTFVIARVHPPAAGGGVPLVHVDAYRLGSLDELDDLDLDASVEQSVTVVEWGEGKAEVLTDDRLDIVISREYAEELDDPGDSEVRWVVVRGIGERWTDRDLAALEDAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4A6</accession>
    <name>C7Q4A6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ordered locus">Caci_1040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1040"/>
    <dbReference type="EnsemblBacteria" id="ACU69966">
        <property type="protein sequence ID" value="ACU69966"/>
        <property type="gene ID" value="Caci_1040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1040"/>
    <dbReference type="eggNOG" id="COG0061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_0_0_11"/>
    <dbReference type="OMA" id="LNEMCIK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="70"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="139"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="180"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="29777" checksum="BB8ACDE7FFF97844" modified="2009-10-13" version="1">MGLISTVGLVLHPERTSAPTVETVVRWSRGRDAKVLGLTEEVARIGCEAVPVGAEEMNASADLVVSLGGDGTMLRAMRLAVGGRAPVLGVNVGRLGFLAEIDIPDLPAALDAIDQHSFTVEARSGVRVRFGADEVTALNDVVLVRSPGHKSAAVAVRVQGQPFVRYSADAVVVATPTGSTAYSFSAGGPIVSPRAEGLLVTPVAPHSAFNRSIFLSSGEELTLEVLPTSGDLAIEADGQLVGTVYPGDVVDVTMLPAAARIVRLGQTTFYQRAQRKLMLSGSAEPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4L3</accession>
    <name>C7Q4L3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF3817 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_3073</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787275.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3073"/>
    <dbReference type="EnsemblBacteria" id="ACU71982">
        <property type="protein sequence ID" value="ACU71982"/>
        <property type="gene ID" value="Caci_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3073"/>
    <dbReference type="eggNOG" id="ENOG50330UF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120964_1_3_11"/>
    <dbReference type="OrthoDB" id="1709780at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3817" evidence="8">
        <location>
            <begin position="10"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15979" checksum="6DF3944A5B99BCC2" modified="2009-10-13" version="1" precursor="true">MTTLTSGAIKRYRVMALFTGTMLLLLTFVVIPLQLWAHNKTLEKPVSIIHGYGYMVYLIVALDLCLRARYKPIRTILILLVGVVPFLAFYYERIVVRDTQRLLTEAQERTAKKKAKAAAKTARTKVAVGAQATAPEPESAQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4L9</accession>
    <name>C7Q4L9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787281.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3079"/>
    <dbReference type="EnsemblBacteria" id="ACU71988">
        <property type="protein sequence ID" value="ACU71988"/>
        <property type="gene ID" value="Caci_3079"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3079"/>
    <dbReference type="HOGENOM" id="CLU_780079_0_0_11"/>
    <dbReference type="OrthoDB" id="2142978at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="38958" checksum="26753177CD826296" modified="2009-10-13" version="1" precursor="true">MTEAVTTALPGTAPEPAPAPAPKVTLPRELIRVLRVWPDWLFGMFASMGMGLATGAFLYWDPFGARIRDPLTLIVTTVLTAAADASLTNQLAAEPEWAIRVLSAGGDPARMLRVRNQVLYLFEAGFAFGVAGLVILLTKDHHWVKHNWPIIAELPLAPIAAGNLASVLFPCPFMRLRHRLQATTTWPRWGAYIGIPFALTSLGTVTVMGFPAWMEQQVKHSADKMHHRPAWLSADNIHFATWLIAVPLLNLLIWAIALKAADSLAHLRRRHLVLLMRKHTELALDLDDISLWEAVKALPANLRTIPSEVHEAASAEIEQVRQAGGHLDRGLEHALARQAAKIRAKRAAEQSAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Q0</accession>
    <name>C7Q4Q0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="10">PRA-PH</shortName>
            <ecNumber evidence="3 10">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisE</name>
        <name evidence="11" type="ordered locus">Caci_3110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="3 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3110"/>
    <dbReference type="EnsemblBacteria" id="ACU72019">
        <property type="protein sequence ID" value="ACU72019"/>
        <property type="gene ID" value="Caci_3110"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3110"/>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123337_2_0_11"/>
    <dbReference type="OMA" id="WMAAEYQ"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU72019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11925" checksum="617348D3C644CB2C" modified="2009-10-13" version="1">MNASPTADDPVEVPVGTAVPITAKSFETLFGELTAKAERAEEGSRTVELLGLGVHAIGKKIVEEAAEVWMAAEYEDGDRTAEEISQLLYHVQVLMLARDLKLEDVYKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Q2</accession>
    <name>C7Q4Q2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ordered locus">Caci_3112</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787314.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3112"/>
    <dbReference type="EnsemblBacteria" id="ACU72021">
        <property type="protein sequence ID" value="ACU72021"/>
        <property type="gene ID" value="Caci_3112"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3112"/>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_1_1_11"/>
    <dbReference type="OMA" id="YVMMDYD"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="49"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="212"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU72021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="30816" checksum="94243C169F4D5A3D" modified="2009-10-13" version="1">MLRIALPNKGSLSEAATAMLHEAGYRQRKDGKELMVVDPANNAELFYLRPRDIATYVGSGRLDVGITGRDLMLDSGASAEPIMDLGFARSTFRFAALPATVEQVAKEAGVAGLAGLRIASAYPGVVREFLATAGVSAEVVKLDGAVEVSIALGVADVVADVVETGTTLRHAGLEVFGEPILTSEAQLIRRIGAEESPAVEQFLRRLKGVITAREYVLMDYDIRAENVDRAVQVTPGIESPTVSPLHDKGWVAVRSMVQRGEAQRMMDELWDLGARGILVTDILACRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5P4</accession>
    <name>C7Q5P4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_9042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797579.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9042"/>
    <dbReference type="EnsemblBacteria" id="ACU77855">
        <property type="protein sequence ID" value="ACU77855"/>
        <property type="gene ID" value="Caci_9042"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9042"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_1_11"/>
    <dbReference type="OMA" id="FRAEDYW"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="6"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="33710" checksum="47CEDED176259845" modified="2009-10-13" version="1">MSEIRNVIIIGSGPAGYTAAVYTARAGLNPLVFAGSVTAGGALMNTTDVENFPGFPEGIMGPDLMDNMQKQAERFGAELVFDDVTAVDLSGAIKKVTDSAGTVHEAHTVIVSTGSAYKELGLPDEKRLSGKGVSWCATCDGFFFKGQDIVVVGGGDTAMEEALFLTRFGQTVTVVHRRDELRASKVMQERAFANPKISFVWDSEVAGIEGETHVTGVKLRNLKTGEETLRPAGALFVAIGHLPRTELFHGVLDLDDEGYIKVDSPTTRTSLPAVYACGDVVDHTYRQAITAAGTGCAAALDAERHLSELAHHQPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6A0</accession>
    <name>C7Q6A0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3199</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72106">
        <property type="protein sequence ID" value="ACU72106"/>
        <property type="gene ID" value="Caci_3199"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3199"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038683_1_1_11"/>
    <dbReference type="OMA" id="WASRFTL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="43932" checksum="838E64E5BC1EF5A2" modified="2009-10-13" version="1">MALDRLTAAHAGPSASGGLTAAGKRFRFWGTAYTFLILLTGTNLPTPLYKGYEARFGFSPLTLTLIFTAYVAVLIPSLLVVGPAADAIGYRVMLLPALFVAAGGALVFAFASGTGWLFAGRILQGVAIGAATGPLTATLTELEPHGDRRKAALVSTVATAGGLGLGPLLAGFLAQYAPAPRVLPFALEIGLLVPAVALVLTLPANRARTRWRPRRPEIPAALRSEFATSGTACFAAFAVVGLFLTLIPTYVATLSGSKNLLLGGAAVALMLACSAIAQVVGYGKSARGLEIAGLPLLAVGLVSLAIAGNVSSLALLLGATVVAGAGQGLTFLGGLTAINAVAPADRRADVLSSFFVILYLGVGVPVVGVGFVATQVGLLAAVQYFAWGAAVLCVVVLAVLGRRRTREGDGKTGLAVEAAEAGTAARRRLTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6J9</accession>
    <name>C7Q6J9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine aldolase</fullName>
            <ecNumber evidence="4">4.1.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.1.2.5" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793763.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5175"/>
    <dbReference type="EnsemblBacteria" id="ACU74034">
        <property type="protein sequence ID" value="ACU74034"/>
        <property type="gene ID" value="Caci_5175"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5175"/>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049619_0_0_11"/>
    <dbReference type="OMA" id="ETDCEVF"/>
    <dbReference type="OrthoDB" id="1124266at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004793">
        <property type="term" value="F:threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="39139" checksum="1BBCC8BF1AA29160" modified="2009-10-13" version="1">MTITRRHDPDYRGFASDNYAGIHPEVLEAIAVANGGHQISYGEDVYTEHLQEIFRGHFGPRAETFPVFNGTGANVVALDAMSERWGSVIAAASAHINVDECGAPEKIGGLKLLTVATPDGKLTPDLIDTHAWGWGDQHRAQPLVVAITQSTELGTCYTPEEIKAICDHAHQHGMKVFLDGSRLSNAAATLGRPFREFTTDAGVDVLTFGGTKSGLLAGECIVVLNPDAAHGVMYLRKMSMQLASKMRFLSAQFEALLTNDLWHRNASHANAMATRLADAVRTIPGVTITQQVQANAVFAILPPDVTERLQKRFRFYTWNEHTGEVRWMCSFDTTEPDIDAFADAVREEMAQGSSATAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6L5</accession>
    <name>C7Q6L5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CsoR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793779.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5191"/>
    <dbReference type="EnsemblBacteria" id="ACU74050">
        <property type="protein sequence ID" value="ACU74050"/>
        <property type="gene ID" value="Caci_5191"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5191"/>
    <dbReference type="eggNOG" id="COG1937">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130332_0_1_11"/>
    <dbReference type="OMA" id="EHLTECI"/>
    <dbReference type="OrthoDB" id="1868412at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="10292" checksum="26E3905B3398B220" modified="2009-10-13" version="1">MHGYTDRKDDYTKRLRRIEGQVRGLQRMVDEDKYCIDILTQISAVTKALQSVALGLLEEHVAHCVADALAVGGPEADAKVKEANEAIARLVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Y6</accession>
    <name>C7Q6Y6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_7170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795727.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7170"/>
    <dbReference type="EnsemblBacteria" id="ACU75999">
        <property type="protein sequence ID" value="ACU75999"/>
        <property type="gene ID" value="Caci_7170"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7170"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012042_1_1_11"/>
    <dbReference type="OMA" id="RVSWHHA"/>
    <dbReference type="OrthoDB" id="345602at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="604"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="647"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="745"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="10">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="10">
        <location>
            <begin position="139"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="225"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="259"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU75999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="777" mass="84232" checksum="EFE99754CA8137A0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7T0</accession>
    <name>C7Q7T0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3366"/>
    <dbReference type="EnsemblBacteria" id="ACU72273">
        <property type="protein sequence ID" value="ACU72273"/>
        <property type="gene ID" value="Caci_3366"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3366"/>
    <dbReference type="eggNOG" id="ENOG502Z8X4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023725_0_0_11"/>
    <dbReference type="OMA" id="FWNVNAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045592">
        <property type="entry name" value="DUF6461"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20062">
        <property type="entry name" value="DUF6461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="714" mass="75554" checksum="E08304EF38A95073" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q861</accession>
    <name>C7Q861_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793957.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5369"/>
    <dbReference type="EnsemblBacteria" id="ACU74228">
        <property type="protein sequence ID" value="ACU74228"/>
        <property type="gene ID" value="Caci_5369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5369"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_0_0_11"/>
    <dbReference type="OMA" id="IMAMLNE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28429" checksum="4F86ED7CD56B978C" modified="2009-10-13" version="1">MKEELLDAVLPEERRLRIAAQLRRDTRVRVEDLAARYGVSGETIRRDLQVLEERGILRRVYGGAVAQESRGWEPGADERAIARLDPKRAIAAAAAALVEPGETLVFDLGTTVAETARALPATFSGRALCVALPTAAELAGREGVEVHLAGGQVRRGDLACVGPGSEKFFERFFADRAFIAASGVHLKAGVTSDRLEEIPVRQAILGQAQAVYVLADGAKLGRVAVGRVCQLSAVTAIVTDSGADPEAVRALEQSGTRVIVAPTGSELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8C6</accession>
    <name>C7Q8C6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ordered locus">Caci_7285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7285"/>
    <dbReference type="EnsemblBacteria" id="ACU76114">
        <property type="protein sequence ID" value="ACU76114"/>
        <property type="gene ID" value="Caci_7285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7285"/>
    <dbReference type="eggNOG" id="COG1077">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052037_0_0_11"/>
    <dbReference type="OMA" id="MVICIPS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="36853" checksum="76E50DC30E00A937" modified="2009-10-13" version="1">MGSGMAVIGRDIAVDLGTANTLVYVRGRGIVLNEPSVVAVDTTTGAVLAVGAEAKKMIGRTPGNIVAIRPLKDGVIADFEVAERMLRYFIRKAHKRRWLAQPRVIVCVPSGITGVEKRAVEDAASAAGARSVHLIEEPMAAAIGAGLPVQEATGNMVVDIGGGTTEVAVISYGGIVTALSVRVAGDELDNAIIQYTKKEYSLLLGDRTAEEIKVTVGSAWDSGEETRAEVRGRDLVSGLPKVILLSSGEVRKAIEEPVTAIVDAVRDTLDKCPPELAGDIMDRGIVLTGGGAMLHGLDERIREETGMPVHIAENPLDSVVLGSGRCLEEFEALAPVLGSLNNRRRPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8S3</accession>
    <name>C7Q8S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA mismatch endonuclease Vsr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the Vsr family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1415"/>
    <dbReference type="REBASE" id="21657">
        <property type="entry name" value="V.CacDORF1414P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70338">
        <property type="protein sequence ID" value="ACU70338"/>
        <property type="gene ID" value="Caci_1415"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1415"/>
    <dbReference type="eggNOG" id="COG3727">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111913_2_1_11"/>
    <dbReference type="OMA" id="GCPQHAT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00221">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004603">
        <property type="entry name" value="DNA_mismatch_endonuc_vsr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03852">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00632">
        <property type="entry name" value="vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="14273" checksum="E0CB1DE9F81EB1BB" modified="2009-10-13" version="1">MQGNRGRDTRPEIAVRSALHRAGLRYRVNFRPLTELRRTADIVFTKAKVAVFIDGCFWHGCPEHHRASHVNASYWKEKIATNKARDADTERRLQVAGWTVIRAWEHEAPDAVADRVIATVRIQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q954</accession>
    <name>C7Q954_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787667.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3468"/>
    <dbReference type="EnsemblBacteria" id="ACU72374">
        <property type="protein sequence ID" value="ACU72374"/>
        <property type="gene ID" value="Caci_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3468"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_2_3_11"/>
    <dbReference type="OMA" id="SNANYEA"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983036" evidence="1">
        <location>
            <begin position="35"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="89"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="43304" checksum="DE380E5ED979F42B" modified="2009-10-13" version="1" precursor="true">MSNHTSSFRRYRAVVAPLAVAAVLSTAVAGGAQAASRHPSPSPARTLGALADQVVAAGAPGVLVRVDSGRDAAPIEVTRQASWARSDGSLDADDPVRMGSNTKTMVATLVLQLVAEHKLALGDSVESRLPGMVPNGSAITIRMLLDHTSGLYNYLDDPAVLASFIGQNPHDWTPEELLAVGVSQPALFAPGSQFSYSNTNYIALGLILQKTTGHSLADLIQQRIVRPLGLHNTYLATPSSPVTKLADGYEPDAADIAPYLPPGVPAGTSFVGPARADYVDVTEINPSNLWGAGGIVSTADDWARFDSALMSGKLLPAAELREMRETVPEDPAQPDGDGYGLGLRKVVFPCGTVWGHDGQAPGYSSQTYTDITGTRTVEIVAPTIFGLAAPKTAAAYQSLTNAAVCAMLGRPIPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA68</accession>
    <name>C7QA68_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785760.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1545"/>
    <dbReference type="EnsemblBacteria" id="ACU70466">
        <property type="protein sequence ID" value="ACU70466"/>
        <property type="gene ID" value="Caci_1545"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1545"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="270" mass="28877" checksum="56449508F311F030" modified="2009-10-13" version="1">MSIPSDNPILLARDFGPDALTLAVGEGEIVALPGACDEGFLRALSGADPAWPGGLWLQGEPLHTLRPAARLRFAHTQCAVAPRVGKLLPELTVAENTALPLILTGLGRQEARRRALRWLERLDAAACAEWRIADLTPSEMRRVALARALVLDPAILLAEDPTDGLSAPERLHLLRILRAASGTHGLTIIVATDDEDVLRWADRSITVKVKTPAAEPANTELAAEPLPAPITEPAAMMNHAAHGGIPHRIGRHARGEHRFSPVGSGAERGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC0</accession>
    <name>C7QAC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792148.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3513"/>
    <dbReference type="EnsemblBacteria" id="ACU72419">
        <property type="protein sequence ID" value="ACU72419"/>
        <property type="gene ID" value="Caci_3513"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3513"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070294_1_0_11"/>
    <dbReference type="OMA" id="YEMAPLP"/>
    <dbReference type="OrthoDB" id="1755236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982952" evidence="2">
        <location>
            <begin position="29"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="28345" checksum="4C69AE185B1810E8" modified="2009-10-13" version="1" precursor="true">MSIALAVTAALLAAMAFAVAAVLQQAAAASVPESKSLHPSLFVSLVRRPAWVAGAVLDVASYVIQGVALAFGPLVLVMPLASTDLVFALPLLAWRGGRRLTRAEVAGAACTAGGMAAFLVALPSVSGMATPGLADWIPLLAVVVVLAGVLLAIGIRVSGNIRTGLYAAAAGLLLALLDALTKSAADLFRNDGLAALGHWEPYALIAVGGSGLLLVQSSYQAGSLAISLPVIDTVEPVGSVLMGAVVFQEPLATSWALAGQVAAGALAVAGIVILSRSTLVQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC7</accession>
    <name>C7QAC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3520"/>
    <dbReference type="EnsemblBacteria" id="ACU72426">
        <property type="protein sequence ID" value="ACU72426"/>
        <property type="gene ID" value="Caci_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3520"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106739_0_0_11"/>
    <dbReference type="OMA" id="PRRCHSK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25581" checksum="64F79FFF6F6943FC" modified="2009-10-13" version="1">MSVSTTEDAATAVIDPMFAQMFGATAGHADAITELTEREKTFLRVTAAVCQAGLGHVFDAYVRLGVEHGVSTSEVRALLRFISYDCGYHAAAAGFERLAAFEARHGIVPDAVEPLGEAFVSTGADAVPSALPETARDILRDLDPHYLEFFDLQSRMRSGHGPDTLTERERGLVCLSIDVHYQTLEESFNAHASRAIRGGASQEEVRAALRFIAQFGATRVWRGWKALNAYFAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV3</accession>
    <name>C7QAV3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NIPSNAP family containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794155.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5567"/>
    <dbReference type="EnsemblBacteria" id="ACU74426">
        <property type="protein sequence ID" value="ACU74426"/>
        <property type="gene ID" value="Caci_5567"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5567"/>
    <dbReference type="eggNOG" id="COG5470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149116_1_0_11"/>
    <dbReference type="OMA" id="CFIRYQI"/>
    <dbReference type="OrthoDB" id="1925073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="1">
        <location>
            <begin position="7"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="106" mass="12311" checksum="35CC709415166DFD" modified="2009-10-13" version="1">MITCVVEYVIDPAKTEAFERFGRRWMELVDKHGGTHHGYFLPSEGASDKALALFSFPSLAAYEEYRTLFGRDAEFIEADRIRDESGCVLRYERTFMRPLLPETPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAW7</accession>
    <name>C7QAW7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794169.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5581"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74440">
        <property type="protein sequence ID" value="ACU74440"/>
        <property type="gene ID" value="Caci_5581"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5581"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_13_2_11"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="28327" checksum="AEA46A96B53AB6FA" modified="2009-10-13" version="1">MSSVEQGNPKVSVVIPAYNEGENIVPVLDRLFEAVSMPCEVLVVVDSPEDLTVPIIERYAEHEPRLRCLINTYGRGPANAIRFGIDTAKSPAAVVTMADGCDDPRQIDILARLVERGVAVAAASRYMPGGQQVGGPLFKGTLSSMAGRSLAFFARVGTRDATNSFKAYSTDFVREVGIDSRDGFEIGIELTAKARRLRRPVAEIPTIWLDRTLGESNFQLSKWLPKYLKWYRLAFGPPLTLEQLQLLNKKERDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAX4</accession>
    <name>C7QAX4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794176.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5588"/>
    <dbReference type="EnsemblBacteria" id="ACU74447">
        <property type="protein sequence ID" value="ACU74447"/>
        <property type="gene ID" value="Caci_5588"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5588"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_0_0_11"/>
    <dbReference type="OMA" id="FMLEIMP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="28821" checksum="BB75F85FE667FDCE" modified="2009-10-13" version="1">MNPPQVIATDLDRTLLRSDGTTSERTRAALDLAMERGAQVIAVTARPIRWLDRLKPCFGRLPHVIASNGAVCYDLATAVAYDARPFDPATLPALLADLRAALPTARIALEAAQGMVREAGYELSLFDQDDEDAGRRVVPFEDLAAAVADGALLKILITDRGRNSADMFAEALPAVGMLGHLTYSTPRGVLELGPPGVTKATTLASWCAARGIEAADVVAFGDMPNDIPMLSWAGRSWAVANAVEEAKASAKAVTATNDEDGVAQVIEELFHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB39</accession>
    <name>C7QB39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7505"/>
    <dbReference type="EnsemblBacteria" id="ACU76330">
        <property type="protein sequence ID" value="ACU76330"/>
        <property type="gene ID" value="Caci_7505"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7505"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123909_1_0_11"/>
    <dbReference type="OMA" id="GYPVNWP"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="16803" checksum="1821000C6555A0B0" modified="2009-10-13" version="1">MIRPRRDEDLPACAAALRGVHESDGYPVHWPADPGRWLTPKTMLGAWVAVAGPAVLGHVALTESGDAIAQAVGIAAPELALVSRLFVAVDARRGGVARDLLDCAARAASDSGLQAVLEVHAIAAGAIALYERAGWRYVGSGEGAWTAADGLPAKVRFYIGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE5</accession>
    <name>C7QBE5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785816.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1601"/>
    <dbReference type="EnsemblBacteria" id="ACU70522">
        <property type="protein sequence ID" value="ACU70522"/>
        <property type="gene ID" value="Caci_1601"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1601"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_6_0_11"/>
    <dbReference type="OMA" id="PDRANYR"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="17"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="150"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="39327" checksum="C79E3CAD08121C43" modified="2009-10-13" version="1">MGDTVNADDTAKDRSVLRVGVVGVGNISGQYLQAIPRLTNLKVTAIADLDAERAAKAAAEVPGARSVKPDELYAAEDVDLVLNLTIPAAHAEVAQLAIAGGKHVYGEKPLAATTAEARVVLESAERAGVRVGCAPDTVLGTGIQTARAVLDAGDIGVPVAATAFMVTPGHERWHPAPEFYYRPGGGPLLDMGPYYLTALITLLGPVKRVVGMSSTPRPTRVVGSGPRAGTEFGVEVETHVTGVLEHEGGALSTLVMSFEVWAGQLPRIEVYGTGGSLEVPDPNGFDGEVSIFRAEAKEWEQVPESGGYRDASRGYGVSDLARALGEGVPHRANGQLAFHVLDVMESLLAAAKSGESVTVGSTCERPAAVPAAARPEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBJ6</accession>
    <name>C7QBJ6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ordered locus">Caci_1652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785867.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1652"/>
    <dbReference type="EnsemblBacteria" id="ACU70573">
        <property type="protein sequence ID" value="ACU70573"/>
        <property type="gene ID" value="Caci_1652"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1652"/>
    <dbReference type="eggNOG" id="COG2001">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107907_0_5_11"/>
    <dbReference type="OMA" id="RGQERCL"/>
    <dbReference type="OrthoDB" id="1684767at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="15997" checksum="C4D8BA5093BEEF6B" modified="2009-10-13" version="1">MFLGTYTPSLDDKGRLILPARFREELAAGLVVTKGQERCLAVWTAEGFAELTAQMRNASRAGSADAAIGRSSRDYHRVFFASAYDCQPDTQGRIVIPPPLRAYAGLSRECVVIGADTRLEIWDAEAWADYLDAAESAYSASGSEAAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS4</accession>
    <name>C7QBS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3640"/>
    <dbReference type="EnsemblBacteria" id="ACU72543">
        <property type="protein sequence ID" value="ACU72543"/>
        <property type="gene ID" value="Caci_3640"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3640"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896283_0_0_11"/>
    <dbReference type="OMA" id="ANLEHTS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="33667" checksum="2447469A74F5559F" modified="2009-10-13" version="1">MVTIDMDQMTAHALRHLLHGAGEHWADGAALSRPTHVDVERLGTVLRAVNSALGGNLPASRLGAPEPAILTPGLPDHEYNLARALADVGTWLTSTGQRHRGLFAFDGAVALYRQLAADDPAVYDPYLAGALTTLGRHMFMTEFVNEALSSLEQALEIHRRLAADNPAVYEPYLAQSLCNLGIALAEVLRRDEALTPVEEAVEIYRRLAADDPAAHEPGLAHALTNLCDRLSGVHREQEALTALDEAVTIYRRLATDNPVYEGHLFRFLDSLSNRLSGLGRHDEAHAAGEESKAIKDRLAARSSARETTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS6</accession>
    <name>C7QBS6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3643"/>
    <dbReference type="EnsemblBacteria" id="ACU72545">
        <property type="protein sequence ID" value="ACU72545"/>
        <property type="gene ID" value="Caci_3643"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3643"/>
    <dbReference type="eggNOG" id="ENOG5032Z70">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063873_0_0_11"/>
    <dbReference type="OMA" id="FTHLDRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025238">
        <property type="entry name" value="DUF4184"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13803">
        <property type="entry name" value="DUF4184"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="26743" checksum="11FAB5A9F59E8488" modified="2009-10-13" version="1">MPFTLAHPAAVLPLTRRGRARGGLVGSALVFGSIAPDVPYFAGAFGVGDLAHTWAAVPTLDLGIAFVLAGVWHRVLRAPLVGLLPVRWAAAADQLTAPRERRVRFSSVSWFVLSAVIGTVTHVVWDGFTHPGRFGVRLFPVLQNARVLGEPPYVLLQYGCSVLGVGALGFWTVREMRRAVRSGTSAAPPAGNRQLAFGLIAVSAILGTAYRAAEWAHPGMPWTSLVPVLAFGAVAGAAIAVLLYSLLILRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC20</accession>
    <name>C7QC20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3737"/>
    <dbReference type="EnsemblBacteria" id="ACU72639">
        <property type="protein sequence ID" value="ACU72639"/>
        <property type="gene ID" value="Caci_3737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3737"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="WVGRRVW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="33788" checksum="68C93BE224C9B6FC" modified="2009-10-13" version="1">MVKAVAIQSFGDPEGLRVIEVPVPVPGSGQVLVTPTAIGVGGVDVVIRRGGLKAYGFGEGHIPGSEVAGTVTAVGEGVDASWVGRRVWAYTGFGGGYAEQVAVGVEDVVPLPADLSDTDAVTLGNSGVVAHFSLAHAHFTPGESVLVRGAAGSIGVTAVQLAARGGAGAVAVTTASPERRERLRALGASHVLDRRGEAAARDTAARETGSDAPAGFDVIIDVVAGADLPSFVRKLNPNGRMVIVGVVGGQPPSDFGTTMMDTFQKSPSIAAFSAASIPASERHAVRAEQFAEAARGELRTVVHEVLPLEKAVLAHQKMEAGEVFGRIVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCB8</accession>
    <name>C7QCB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5708"/>
    <dbReference type="EnsemblBacteria" id="ACU74566">
        <property type="protein sequence ID" value="ACU74566"/>
        <property type="gene ID" value="Caci_5708"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5708"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101331_0_0_11"/>
    <dbReference type="OMA" id="LLIWPRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="179" mass="19025" checksum="0139BEA4B61BFE5A" modified="2009-10-13" version="1">MTSMASKASAPGKDAPATGGIRGLLDTNQQWISLGMRLLLAAMWLYYSLGKLGSPESNAQSVRDFKILPESLVTPFGYAQPYFEMALGILLILGLGTRLVAIFSALLLLVYIGGIMSLGARGIAISCGCGGSGGLVPKGHTRYTLDVLRDLLYVLPAAWLIWKPASKLSLERALLGDPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCG0</accession>
    <name>C7QCG0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794337.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5750"/>
    <dbReference type="EnsemblBacteria" id="ACU74608">
        <property type="protein sequence ID" value="ACU74608"/>
        <property type="gene ID" value="Caci_5750"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5750"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="NANAPFE"/>
    <dbReference type="OrthoDB" id="1186918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="30075" checksum="A709924D84B127A8" modified="2009-10-13" version="1">MPKQPLQGEEPTADSSSLPPSVDISVAHPARMYDYYLGGKDNYPADRAAAENVLAVLPEGRDMAIANRAFLGRAVRHLADAGIDQFLDIGTGIPGPGNTGQVADAVRPGSRVVYVDNDPIVLAHSRALLARHDPDRTAVVQADLRSPAAILNHHDVRTVLDFTKPIALLLVAVLHFIKEEEDPAAIVAELLAALAPGSYLVISHGTDEFDTSRARAAVRNYDKATAPFVLRSHNQIHAFFDTLKLDAPGLVQLPWWRPDGEIPPGSEAIWLYGGVGRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCK2</accession>
    <name>C7QCK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7641"/>
    <dbReference type="EnsemblBacteria" id="ACU76465">
        <property type="protein sequence ID" value="ACU76465"/>
        <property type="gene ID" value="Caci_7641"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7641"/>
    <dbReference type="eggNOG" id="COG0381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041674_0_1_11"/>
    <dbReference type="OMA" id="WFPYPEE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="37"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="40447" checksum="F0F45BFB24F561FF" modified="2009-10-13" version="1">MPGQAAERTRTAEALRIICVAGARPNYMKIKPVMDALEARGAEVVLVHTGQHYDEAMNDVFFRDLGIRPPDRYLGAGSGSQAEQTARIMLAFEPVVAELAPDAVVVVGDVTSTVACGLVAAKAGTLLAHVEAGLRSRDWSMPEEVNRVVVDRLSDYLLAPSQDAVDNLRAEGYREDQVHLVGNVMIDTLFANRERALAAGALEQLGLTPGGYGLVTLHRPANVDSPEALAPLVGALAKVAEELPLILPAHPRAASALRELVATDRIRLIPPAGYLDFVALQAGARIVLTDSGGVQEETTALGVPCVTLRDNTERPITVSEGTNILAGLDPARIVEIAQRVLAAPPAPRRPALWDGHAGERIAEVLLGGGSAATRLRPTDLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCV0</accession>
    <name>C7QCV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1739</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785954.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1739"/>
    <dbReference type="EnsemblBacteria" id="ACU70660">
        <property type="protein sequence ID" value="ACU70660"/>
        <property type="gene ID" value="Caci_1739"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1739"/>
    <dbReference type="eggNOG" id="COG0025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005912_8_2_11"/>
    <dbReference type="OMA" id="TPPFWAS"/>
    <dbReference type="OrthoDB" id="1194802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004705">
        <property type="entry name" value="Cation/H_exchanger_CPA1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00831">
        <property type="entry name" value="a_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0050">Antiport</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0915">Sodium</keyword>
    <keyword evidence="5 6" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="7">
        <location>
            <begin position="16"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="536" mass="58213" checksum="E3F82C552378B0BD" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCY7</accession>
    <name>C7QCY7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiosulfate sulfurtransferase</fullName>
            <ecNumber evidence="2">2.8.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.8.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785991.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1776"/>
    <dbReference type="EnsemblBacteria" id="ACU70697">
        <property type="protein sequence ID" value="ACU70697"/>
        <property type="gene ID" value="Caci_1776"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1776"/>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_0_0_11"/>
    <dbReference type="OMA" id="LLDVRWQ"/>
    <dbReference type="OrthoDB" id="920668at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="PTHR11364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00380">
        <property type="entry name" value="RHODANESE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="32"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="181"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="31064" checksum="1D293E4256022A23" modified="2009-10-13" version="1">MRQPGTAPSSSDSPLTSVDQLAADLACGTAPILLDIRWKLGEPSEYGHGVYLKGHIPGARYVSLDQDLAEHPDSPVGARGRHPLPDRERFAAAMRHAGVRADLPVVVYDDGDGTQAARAWWLLRHHGHAEVRVLDGGFAAWRAAGRTVEEGEPEAEAAEGDFEASGDGVFTVLDHDGAAAVAADGTLLDARAGARYRGETEPIDPAAGHVPGAVSAPTTENLGADGRFLPSEALAERFAGLGVEAGHAGAVAVYCGSGVTATHEILAMAVAGIDPEGVALYEGSWSGWASDPSRAVATGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF4</accession>
    <name>C7QDF4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792476.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3850"/>
    <dbReference type="EnsemblBacteria" id="ACU72747">
        <property type="protein sequence ID" value="ACU72747"/>
        <property type="gene ID" value="Caci_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3850"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1056431_0_0_11"/>
    <dbReference type="OMA" id="QCVDYEL"/>
    <dbReference type="OrthoDB" id="1101420at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="29333" checksum="853B9669BEFE3208" modified="2009-10-13" version="1">MIVEYIRYLIPADSSEQFESAYARAASASLAVAPQCVEYELARCTEAPDHYILRIVWTSADDHLHGFRGGPHFAAFFAEIKPYVTAIEEMRHYERTAVRGQGGSVPTMFDWLGGAKALERLTDVFYDHVLADEVVGPLFAHMDPAHPHHVALWLGEVFGGPSRYTAERGGYHHMITQHLGKAITEPQRRRWTNLLMDAADEVDLPSDPEFRAAFASYIEWGTRLALTNSQPGATPFTHARVPHWEWGAGITPPYRSAASKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDI4</accession>
    <name>C7QDI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792506.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3889"/>
    <dbReference type="EnsemblBacteria" id="ACU72777">
        <property type="protein sequence ID" value="ACU72777"/>
        <property type="gene ID" value="Caci_3889"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3889"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_314898_0_0_11"/>
    <dbReference type="OMA" id="WRYAIAF"/>
    <dbReference type="OrthoDB" id="865342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="928" mass="102854" checksum="BA5A158D938DC06A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE83</accession>
    <name>C7QE83_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1854"/>
    <dbReference type="EnsemblBacteria" id="ACU70774">
        <property type="protein sequence ID" value="ACU70774"/>
        <property type="gene ID" value="Caci_1854"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1854"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288158_0_0_11"/>
    <dbReference type="OMA" id="THAHERT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="699"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="859"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="929"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="274"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="728"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="951"/>
            <end position="1042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1067" mass="105460" checksum="91DE40B8ACEC6206" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEB5</accession>
    <name>C7QEB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1886"/>
    <dbReference type="EnsemblBacteria" id="ACU70806">
        <property type="protein sequence ID" value="ACU70806"/>
        <property type="gene ID" value="Caci_1886"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1886"/>
    <dbReference type="HOGENOM" id="CLU_159099_1_0_11"/>
    <dbReference type="OMA" id="GPPAWSS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14533" checksum="DB31649709675901" modified="2009-10-13" version="1">MYPRPFYGPGRHVHEGLGWGGWVLWVLFMVALWALVIMAVVWLVRSFTHRGPVTAQRGMRLPGGPPAWSSGGTGTVPAEQILAERFAHGQIDENEYRSRLDVLRGNRPAAQTAPPAPPQPSQPPEPPEPPGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN6</accession>
    <name>C7QEN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792535.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3920"/>
    <dbReference type="EnsemblBacteria" id="ACU72806">
        <property type="protein sequence ID" value="ACU72806"/>
        <property type="gene ID" value="Caci_3920"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3920"/>
    <dbReference type="eggNOG" id="COG3618">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_2_1_11"/>
    <dbReference type="OMA" id="EFLLECM"/>
    <dbReference type="OrthoDB" id="1979322at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="4"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="30780" checksum="A6AA7AC1F139EEC2" modified="2009-10-13" version="1">MDVIDTHCHVISPDLDAYPHAPIGGKQSEWAASRPITAEGMVAAMDEVGIRQSVLVQATTNYGYDNSYVVDSRRRYPERFIAVGTFDPLAPDAGSRLKALTADGGLSGVRLFTSGSTVPTQGEWFAAPETHEFWRTAEQTGVPVCLQMRLGPATTQLVDVLGRFPEAKVLLDHFGYPDIAASPLRAGQEVAKLAKHPGLYLKLTHRNLERLQDVGDKAVEFLQRVVEAFGSERIAWGSNCPAAEQSLPELLGLAEGVLAVLSDEARADIFAGTARQLYPGLGPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF74</accession>
    <name>C7QF74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5974"/>
    <dbReference type="EnsemblBacteria" id="ACU74832">
        <property type="protein sequence ID" value="ACU74832"/>
        <property type="gene ID" value="Caci_5974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5974"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_0_1_11"/>
    <dbReference type="OMA" id="WGYTGNA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="411" mass="42992" checksum="CFE64AFAC5D48F23" modified="2009-10-13" version="1">MVGPSFDPSPSDSAPGNGSGGDAAAAPAPRSITPTTVKDLRDAVSTVGAVLIRGTGTATTWGAPVRDARTTVSLAGMDRVLDHRPADMTVHVQGGIRLDVLQAELAEHGQWLPYDPARSEATIGGLLATGDAGPRRLAYGSLRELVIGATMVFPDGAIAKSGGHVIKNVAGYDLAKLCHGSLGTLGVVAELVLRVHPLPQTSRTVMVRDVDTAAAQQLTWALTRSAIEPTAVEWCEPEQVLAVRFDGTADGAAARAASARSMLTGSLAELDAGEAHSFWESHAARVVAEPGDTVLRAATRPGIDPGLVRALSMFAEFAGVKALLTCSPATGAYTVRVTGADAKAHAEVVKNWRGSVEAVGGFVMLRRRRPGVDAMVESWGRAPGSVEVMRRVKGNFDPENRFAPGRFAPWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ4</accession>
    <name>C7QFQ4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0038"/>
    <dbReference type="EnsemblBacteria" id="ACU68993">
        <property type="protein sequence ID" value="ACU68993"/>
        <property type="gene ID" value="Caci_0038"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0038"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_135_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="301"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU68993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="700" mass="73011" checksum="51D021C4864D998E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFT3</accession>
    <name>C7QFT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1990"/>
    <dbReference type="EnsemblBacteria" id="ACU70910">
        <property type="protein sequence ID" value="ACU70910"/>
        <property type="gene ID" value="Caci_1990"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1990"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_5_11"/>
    <dbReference type="OMA" id="ARAWDRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="100"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="171" mass="18434" checksum="4996617C13FA61EC" modified="2009-10-13" version="1">MATTSFDDVYAATAPRLIGQLYLVTGDLAEAQDCVQEAYARAWTRWDKLTRNDGDPVGWVRSTAYRLAVSRWRHHTAGLRAFMRHGAPGEMAPPSADTIAVRDALAELPKGLRAALVMYYLGGMQVAEVATALDLPQGTVKARLSRGRAAMAVMLTDTADFGDGAVEAAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG37</accession>
    <name>C7QG37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786307.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2095"/>
    <dbReference type="EnsemblBacteria" id="ACU71014">
        <property type="protein sequence ID" value="ACU71014"/>
        <property type="gene ID" value="Caci_2095"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2095"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2069676_0_0_11"/>
    <dbReference type="OMA" id="IAVGCHE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="14587" checksum="ACF9EF30FC3464F8" modified="2009-10-13" version="1">MRDPNDDLVRGFARACRRGDVAALRATLAADVIAVSDSGGRLPALPGLVRGAQDVARLAAALLGESGLLWGSGSMSGPGSLDEPGEPGEPGDAELSTEVVNGRAGLALRRTGRAVAVVGIDGTAAGITALWIVLNPDKLGGWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA4</accession>
    <name>C7QGA4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4084"/>
    <dbReference type="EnsemblBacteria" id="ACU72949">
        <property type="protein sequence ID" value="ACU72949"/>
        <property type="gene ID" value="Caci_4084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4084"/>
    <dbReference type="eggNOG" id="ENOG50338MW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134413_0_0_11"/>
    <dbReference type="OMA" id="TCFKSAG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043993">
        <property type="entry name" value="T4SS_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18895">
        <property type="entry name" value="T4SS_pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="14107" checksum="AE1BE886D0A44C3C" modified="2009-10-13" version="1" precursor="true">MHQQIDSARPETGEPADIAASSARPRRRHLRIAAAVTSGALLAALGASPAMAAVSGDGGQYLAAADIPTVISNVTNWLIGILAVLATLMLTIGGVRYVLAAGDPAEVEKAKTCFKSAGMGYCLAVLAPVVVTVLKGLVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGB9</accession>
    <name>C7QGB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4100"/>
    <dbReference type="EnsemblBacteria" id="ACU72964">
        <property type="protein sequence ID" value="ACU72964"/>
        <property type="gene ID" value="Caci_4100"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4100"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="HEMEPEA"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="34285" checksum="63D57B580A6032E4" modified="2009-10-13" version="1">MIDVRRLRLLRELSVQGTVTAAAEALHLTGPAVSQQLAALEKEAGVPLLEKHGRTLRLTYAGQRLVEHADVILGNLAAADAELQALRAGQRGTVLITAFPSAARVLLPPLWQLLAQDSEAEVGDVGAMRPELRITEAEPDVSVEMLRRRETDIAVAHAYSLLPRPLPPGCEQHRLMEEPVYLALHPDTAAAHDLTPHQPAELADFRDEGWLLPDPRTYCHELTRRACGAAGFVPSPIAAATDFSVLTALVAARAGVALVPRMALPADTRGVSLHPLTAPVTRSVYALARSGEAGQPRLSRVLEGLQTVALNQYSVTAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS3</accession>
    <name>C7QGS3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794682.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6098"/>
    <dbReference type="EnsemblBacteria" id="ACU74953">
        <property type="protein sequence ID" value="ACU74953"/>
        <property type="gene ID" value="Caci_6098"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6098"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_170329_3_0_11"/>
    <dbReference type="OMA" id="ETHIAFR"/>
    <dbReference type="OrthoDB" id="1855714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9914" checksum="B7D9F6C3AED8C22F" modified="2009-10-13" version="1">MITAIVLIKTDVDAIPEVAEKISRLPGVSEVYSVTGEYDLIAMVRVREHEQLADVIPGGVNKVAGVSHTVTHVSFRTYSAMDLEAAFSLGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH32</accession>
    <name>C7QH32_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclic dehypoxanthine futalosine synthase</fullName>
            <shortName evidence="6">Cyclic DHFL synthase</shortName>
            <ecNumber evidence="6">1.21.98.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dehypoxanthine futalosine cyclase</fullName>
            <shortName evidence="6">DHFL cyclase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Menaquinone biosynthetic enzyme MqnC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mqnC</name>
        <name evidence="8" type="ordered locus">Caci_8059</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dehypoxanthine futalosine + S-adenosyl-L-methionine = 5'-deoxyadenosine + cyclic dehypoxanthinylfutalosinate + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:33083"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58864"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64270"/>
            <dbReference type="EC" id="1.21.98.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. MqnC family.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796607.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8059"/>
    <dbReference type="EnsemblBacteria" id="ACU76882">
        <property type="protein sequence ID" value="ACU76882"/>
        <property type="gene ID" value="Caci_8059"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8059"/>
    <dbReference type="eggNOG" id="COG1060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040406_1_0_11"/>
    <dbReference type="OMA" id="ATMMFGS"/>
    <dbReference type="OrthoDB" id="419725at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046992">
        <property type="term" value="F:oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00992">
        <property type="entry name" value="MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022431">
        <property type="entry name" value="Cyclic_DHFL_synthase_mqnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="PTHR43076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03699">
        <property type="entry name" value="menaquin_MqnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00423">
        <property type="entry name" value="TIGR00423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="62"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="44626" checksum="FB23B1F67ED5CA4F" modified="2009-10-13" version="1">MSKQISAELQDALDRAADGGRIEYEEALELYRHAPLHSLGTAADAARRKRYSGVYGENGEIATYIIERNINYTNACVTACKFCAFYAAPKSDKVWSRPLEDILRRCAETVALGGTQIMFQGGHHPDYGVEYYEENFRAIKAEFPQLVIHSLGASEVQHMAKVSGVTIEEAITRLKESGLDSFAGAGAELLPARPRTAIAPLKESGERWLEIMETAHGLGLESTSTMLMGTGETNAERIEHLRMIRDVQDRTGGFRAFIPYTYQPENNHLKGRTQATMFEYLRLIAVARLYLHNVAHIQGSWLTVGKEAGQLSLHYGADDLGSVMLEENVVSSAGAKHRSNRMELIHLIRAAGRVPAQRSTTYNLITVHDDPANDPVDDHVMSHIASTAIEGGTAHPELKLVDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI11</accession>
    <name>C7QI11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792785.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4192"/>
    <dbReference type="EnsemblBacteria" id="ACU73056">
        <property type="protein sequence ID" value="ACU73056"/>
        <property type="gene ID" value="Caci_4192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4192"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="TTDYRSH"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="18"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="37535" checksum="86B6CA345851AED5" modified="2009-10-13" version="1">MRYTTFGNTGLRVSEAFLGTMGFGEDWGWGVSVEDCRKIFTAYAEAGGNVIDTANRYTDGSSERIVGELLGTDRDRFVLATKYTLSMDDTDPNAAGNHRKNLRRSVEDSLSRLNTDYLDVLWVHIWDAHTPLEETMRALDDLVRSGKVLYLGLSDAPAWVAARAQTMAELRGWTPFAGLQLNYSLLERGIERELLPMAESLNLSVAAWAPLARGVLTGKFTRHGATEGSRTSRDKLTEHDLHIAATLDAVADDLGITSSQAAVAWTRAHHRWIHPIIGARTVDQLNDSVAALDVRLPADAVRRLEEATSFDLGFPQEFIAEAREFVYGPGIERFEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIH5</accession>
    <name>C7QIH5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable phosphoketolase</fullName>
            <ecNumber evidence="5">4.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6198</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794781.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6198"/>
    <dbReference type="EnsemblBacteria" id="ACU75052">
        <property type="protein sequence ID" value="ACU75052"/>
        <property type="gene ID" value="Caci_6198"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6198"/>
    <dbReference type="eggNOG" id="COG3957">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_11"/>
    <dbReference type="OMA" id="LSTMDHC"/>
    <dbReference type="OrthoDB" id="45239at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01403">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023962">
        <property type="entry name" value="Phosphoketolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="7">
        <location>
            <begin position="15"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="XFP_C" evidence="6">
        <location>
            <begin position="597"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="800" mass="89315" checksum="BF008F575001D652" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII9</accession>
    <name>C7QII9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794795.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6212"/>
    <dbReference type="EnsemblBacteria" id="ACU75066">
        <property type="protein sequence ID" value="ACU75066"/>
        <property type="gene ID" value="Caci_6212"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6212"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166867_0_0_11"/>
    <dbReference type="OMA" id="HVKPIAG"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="54"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13407" checksum="9D9B19ACB548B9E6" modified="2009-10-13" version="1">MTGLLHKSLDTPEETRPFEQNMGHLDLVAMDEGGFGRAVFEPGWRWSQHVKPIAHTDSCQAAHLGYCLSGHMHIAMDDGDQADIGPGEFLEIPPGHDAWVVGSEPCVMIDWQGYSDYAKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM4</accession>
    <name>C7QIM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796649.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8101"/>
    <dbReference type="EnsemblBacteria" id="ACU76924">
        <property type="protein sequence ID" value="ACU76924"/>
        <property type="gene ID" value="Caci_8101"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8101"/>
    <dbReference type="eggNOG" id="ENOG5030KI8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100166_0_0_11"/>
    <dbReference type="OMA" id="PPNTHWS"/>
    <dbReference type="OrthoDB" id="1643427at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="23052" checksum="F7B3F6BC1A131F70" modified="2009-10-13" version="1">MTFGQQFLDQLDASAQDFTFPFLDHGFYSAVDVRLHVYRDDKHWAVVFETVGFNPKARSVTDALTGYGVRAGSQLDRVENIAELIDADENYVGGKPLRVRGEDLPVEAPAGEYFAEVVRELVPEYRDLLLADESELRALIPPDLPEILRLEAWHHPDVLVERPSREEVFQLLAKVLDTGNPHEYRPTRAPNTHWSNWPESGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX9</accession>
    <name>C7QIX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8206"/>
    <dbReference type="EnsemblBacteria" id="ACU77029">
        <property type="protein sequence ID" value="ACU77029"/>
        <property type="gene ID" value="Caci_8206"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8206"/>
    <dbReference type="HOGENOM" id="CLU_2245074_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="9807" checksum="C262177EE22A7690" modified="2009-10-13" version="1">MFLDTVPALAVAVAADGTDGDVAAPRKASDRGASAVEWVVITGIVVAIVAGVGWGISKAISGKADQACNQINSAGDNISVTGGGDGGNSGGTTGTTGGTGGCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ51</accession>
    <name>C7QJ51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SEC-C motif domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784488.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0240"/>
    <dbReference type="EnsemblBacteria" id="ACU69193">
        <property type="protein sequence ID" value="ACU69193"/>
        <property type="gene ID" value="Caci_0240"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0240"/>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075039_0_0_11"/>
    <dbReference type="OMA" id="RYKACHG"/>
    <dbReference type="OrthoDB" id="1424843at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045970">
        <property type="entry name" value="DUF5926"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19348">
        <property type="entry name" value="DUF5926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5926" evidence="1">
        <location>
            <begin position="63"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="34823" checksum="3B5BC14876AA0B1F" modified="2009-10-13" version="1">MGKKSSRTAKAGPAKAVDGEIPVVGAREACPCGSGRRYKACHGREAAAAAHQQAAEVTANKRPFEGLPGEADIVAMRELVPAATAPLKLAGEHADRTVTLATVLPMAAPAVHRDTGEIMLALQTLATSGDPDRDLADALLRALDSAPGTVVDSAAPAADGPRLRDLLDTSGDSLGITVHEDFSFWIIDGADVSPEAQLSLEHANAAAYPTKKLESVPSAYWTRIREKGHLRWVMPHEEEKLMDALARLHAAKQSNLGEGTRYVGAFRACGLVVPVWDLPKEMEAAEIEKPAAEFAERLAKALTDDSPLTNDQRRARAGLVSRQVTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJF7</accession>
    <name>C7QJF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2262"/>
    <dbReference type="EnsemblBacteria" id="ACU71180">
        <property type="protein sequence ID" value="ACU71180"/>
        <property type="gene ID" value="Caci_2262"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2262"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078469_0_0_11"/>
    <dbReference type="OMA" id="LCQGHCP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26762" checksum="AD3C345FABB3822B" modified="2009-10-13" version="1">MESVPTPIVSTVSASPSAGDASDVHVGTRNRVARSILANGPSTAVDLGKRLKMTPAGVRRHLDALLAEDLVEARQQRTYGQRGRGRPAKVFALTDRGRGVFYQAYDQLAVDALKFLADSAGSAAVEAFARKRVAELADRFRERMDSVPAEERPALLAKLLTEDGYAAGLRQSGNAPAAGEQLCQHHCPVAHVAEQFPQLCEAETEAFAELLGTHVQRLATIAHGDGVCTTFIPMTATATGTGKSTEVSGGNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK6</accession>
    <name>C7QJK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786522.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71229">
        <property type="protein sequence ID" value="ACU71229"/>
        <property type="gene ID" value="Caci_2311"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2311"/>
    <dbReference type="HOGENOM" id="CLU_1764724_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="15855" checksum="352DAFCF16729B31" modified="2009-10-13" version="1">MAADDLSFVAGFLAASGLFWIGGGVLWLAACARRLARLRLRLVGVPARGEVIGMVVSCDASGTVRNAPRVRYFAQAGPPVVTRAYGYRPHQSVATGAQVRLWYDPLRPERILVSRFDLKPRDWLELVGALAVLAIGVGMEFAALTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM7</accession>
    <name>C7QJM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2332</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786543.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2332"/>
    <dbReference type="EnsemblBacteria" id="ACU71250">
        <property type="protein sequence ID" value="ACU71250"/>
        <property type="gene ID" value="Caci_2332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2332"/>
    <dbReference type="eggNOG" id="COG2183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009833_0_2_11"/>
    <dbReference type="OMA" id="RWAWRTR"/>
    <dbReference type="OrthoDB" id="120764at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="660"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="838" mass="88042" checksum="CF6A8E1316F06376" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK68</accession>
    <name>C7QK68_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyl-ornithine/N-acetyl-lysine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794871.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6288"/>
    <dbReference type="EnsemblBacteria" id="ACU75142">
        <property type="protein sequence ID" value="ACU75142"/>
        <property type="gene ID" value="Caci_6288"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6288"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_0_11"/>
    <dbReference type="OMA" id="HMDTVPG"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01120">
        <property type="entry name" value="LysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010175">
        <property type="entry name" value="LysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01902">
        <property type="entry name" value="dapE-lys-deAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="361" mass="38195" checksum="2F21CCEEC9D324B9" modified="2009-10-13" version="1">MKPFTSSGAVTETYALGLLRNMLEIPSVSYHERALADFLIGAMTDLGFQAHIDEVGNTVGVIDRGAGPTVMLLGHLDTVSGVLPVRPLDGRLYGRGAVDAKGPLAAMICAAAGAADFRGRLVVIGVVEEETPRSRGAMAIRATHERPDALIVGEPSGWSSVVLGYKGKLDLRYTVRCPATHPSNPAPKASELAVACWDALVELLGPEAGHDVFGQPGASLVRISGDQALATADLSVRTPPGFDVEELVRGLRDRLPIGELEVLNSVAACRVGRADPAVRALVSGIRRLHAQPRLVVKTATSDMNTLAEVWDIPMATYGPGDSALDHADDEHIMLSDFRRGIDVLTIAISELAQLPARSGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE4</accession>
    <name>C7QKE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Wyosine base formation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6364"/>
    <dbReference type="EnsemblBacteria" id="ACU75218">
        <property type="protein sequence ID" value="ACU75218"/>
        <property type="gene ID" value="Caci_6364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6364"/>
    <dbReference type="eggNOG" id="ENOG502Z7S3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Wyosine_form" evidence="1">
        <location>
            <begin position="169"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27535" checksum="06BCE8DB76F70637" modified="2009-10-13" version="1">MVSSVYADLISEGEELEALVPLDERWYSQTPAPGWTVGRQIDHMAEVAAMARSAAMPRPIAGANGSPRRPLELVDGPEQTVRRWRTEREAAARALSEADQDRDLPWMRGTGRPSLIGAALAMEMFGHGQDIVDTVGEKRTHTDRIGHVVWFGARTRDFGYRAHGFEAPDKPFRFEITAPSGNLWAFGPEDAEQRVIAPAVDFCLLVTCRRHRDDVDVKAIGREAERWLGIAQCYPGPAGAGRSAGQFGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW48</accession>
    <name>C7PW48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4432</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4432"/>
    <dbReference type="EnsemblBacteria" id="ACU73296">
        <property type="protein sequence ID" value="ACU73296"/>
        <property type="gene ID" value="Caci_4432"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4432"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_3_11"/>
    <dbReference type="OMA" id="WLENIIY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="234"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="41711" checksum="D48285CA4FCD6354" modified="2009-10-13" version="1">MNRLSGPAWSTEERRALRATVRRFTEQEVLPNLDGWERAGELPRELSKKAGALGLLGVAHPVEVGGGGGDLIDAITVNEEMHDAGGSGGLFASLFTCGISTPHLVAANDPEQIERWVKPTLAGEKIGALAVTEPGGGSDVARIQTTARRDGEHFVVNGAKTFITSGVRADYVVAAVRTGDSGASGISLLVVEKDTPGFTVSRRLEKLGWLCSDTAELAFQDARVPVENLVGAENSGFFQLAEHFLSERVALAAQAYSHAQRCLDLAVDWTRKRQTFGKPLIDRQLVQNTLTEMARKIDVARTYTHALIDRSLAGEKDLIAEVCFAKNTAVETAEWVATQALQLFGGLGYMRESEVERHYRDVRILGIGGGATEVMNGLAARVLGFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA1</accession>
    <name>C7PXA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0505"/>
    <dbReference type="EnsemblBacteria" id="ACU69452">
        <property type="protein sequence ID" value="ACU69452"/>
        <property type="gene ID" value="Caci_0505"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0505"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_253575_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980428" evidence="2">
        <location>
            <begin position="28"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="3">
        <location>
            <begin position="587"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1412" mass="142358" checksum="ABE353690CF8BD09" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXM4</accession>
    <name>C7PXM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2559"/>
    <dbReference type="EnsemblBacteria" id="ACU71477">
        <property type="protein sequence ID" value="ACU71477"/>
        <property type="gene ID" value="Caci_2559"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2559"/>
    <dbReference type="HOGENOM" id="CLU_2315147_0_0_11"/>
    <dbReference type="OrthoDB" id="1972413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10832" checksum="535B67261F77B9CC" modified="2009-10-13" version="1">MAGKATIRINGRHSPMAWLLYMTKLTVEIDGTPQPGSWGDRVISVPPGRHDVKIYFKYLTKSRCCEAGATVDAAEGSTIAMEYRTPMMMTAPGRLTVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXQ1</accession>
    <name>C7PXQ1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786797.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2586"/>
    <dbReference type="EnsemblBacteria" id="ACU71504">
        <property type="protein sequence ID" value="ACU71504"/>
        <property type="gene ID" value="Caci_2586"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2586"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="80" mass="8476" checksum="01DDA7E66634546F" modified="2009-10-13" version="1">MQDIQDPGPARAPLVMVSREDCIAAGECARIAPAVFDQDDADGTVLLREGFTSADPQLRKQIRHAVAACPAGALDLVEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY11</accession>
    <name>C7PY11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793200.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73471">
        <property type="protein sequence ID" value="ACU73471"/>
        <property type="gene ID" value="Caci_4610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4610"/>
    <dbReference type="eggNOG" id="ENOG502ZV7C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102930_0_0_11"/>
    <dbReference type="OMA" id="WQALKVF"/>
    <dbReference type="OrthoDB" id="1529411at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20401" checksum="3CC8052664520BF6" modified="2009-10-13" version="1">MTIHIASRRRSAASLSAEFSGARIIDVTSKGPQPWVRMSPFFPHSGIPVPLSDGAVSQSVEGIWQALKVFPGSDVDPRKLDVASMTGLKRTVRKHGPVLGHRAGLNGQDLLPYEQARRRIFLPAYRWVLEHNVTDLIAELRAADGDIVLLDYTVNGDVTDTSSALSHAALIRLYVEDRWPEEHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY96</accession>
    <name>C7PY96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6538"/>
    <dbReference type="EnsemblBacteria" id="ACU75386">
        <property type="protein sequence ID" value="ACU75386"/>
        <property type="gene ID" value="Caci_6538"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6538"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_4_11"/>
    <dbReference type="OMA" id="GWYWENY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="18"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="31487" checksum="209AE9198AF49B5D" modified="2009-10-13" version="1">MPVLAETLEMPVYVVTAATGQLGQLVVRHLLHRVDADQIAVVVRNASRATHPAEHGIEVRVADYDDPASLAGAFGAGDRVLLISGNQFGARLTQHANVIAAAKSSGIAQLAYTSILGGPSANFPVADDHHVTEQALLESGLPFTLLRNGWYTENYTSQLTAALHHGAVVGAAAPASRLATAARADYAEAAAVVLVGAGHENNVYELSGDTAWSLEEYAAEISRQTASTVPYRQLPPADYEDFLAGLGLPTPMLSVFTATEAAIDRGELADTGGDLRRLIGRPTTTLAESIAAELAELTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYG9</accession>
    <name>C7PYG9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795188.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6613"/>
    <dbReference type="EnsemblBacteria" id="ACU75459">
        <property type="protein sequence ID" value="ACU75459"/>
        <property type="gene ID" value="Caci_6613"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6613"/>
    <dbReference type="eggNOG" id="COG2170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044848_0_0_11"/>
    <dbReference type="OMA" id="MLYWYAR"/>
    <dbReference type="OrthoDB" id="991285at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="373" mass="41199" checksum="CF37FF443E4FFFD6" modified="2009-10-13" version="1">MTLKDSRDLELLTVGVEEEFMLVDPVSRFTVPRAPEVHAFAAERLGEQVARELYATQVEINSRPAKQAEVLRQDLVEARRALASAAAHFDCMLVASGTAVLTTKPFPITEGERYEEIAERYSAATTDIDSEASGCHVHVGDLECDEALALAGHLRPWLPVLQVLAVNSPFAAGSFRRVASWRHYQQQAWPITGPTPMMTALEYEARAQELVDAGVLIDKRMIYWYARPSEHQPTLEIRVADVCADVDITLLVAVLTRALAMVLLADVRADTPAPRTEELEVREHHRGAATLGPAGLWTHPLSGVSMPLSAGVEALVAHARPALEMLDETRLVAQLLRRAYHRGTGAQRQRAAYRRRGRLEDVVDELAAQTIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYH0</accession>
    <name>C7PYH0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795189.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6614"/>
    <dbReference type="EnsemblBacteria" id="ACU75460">
        <property type="protein sequence ID" value="ACU75460"/>
        <property type="gene ID" value="Caci_6614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6614"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_3_1_11"/>
    <dbReference type="OMA" id="PECTRVY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="135"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19848" checksum="FDFE1986956B5542" modified="2009-10-13" version="1">MRFEFVAGHVVLDYVATVAERTTTRLERLSTPEDLADWLVKARVVDTPPTAGEADLLAARQLRESLYTLVVSLTGGSALTPAVRETLTRFAAHDGPRLSIDAHGNVHRTGTVTQALALLAQEGLLLARDEQHDSIRWCAAPTCTRPFLDRSHARRRRWCGMSTCGDKAKAAAYRARRANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYP9</accession>
    <name>C7PYP9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797096.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8551"/>
    <dbReference type="EnsemblBacteria" id="ACU77371">
        <property type="protein sequence ID" value="ACU77371"/>
        <property type="gene ID" value="Caci_8551"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8551"/>
    <dbReference type="HOGENOM" id="CLU_2421567_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="9764" checksum="DFA62931650B3077" modified="2009-10-13" version="1">MSPKSPDFEPGTVVRVRTEPTLSEVVLPATRQCEPPAEDLPELLICCTPVALVRTPVGIGVLRWVELRDLTVAEAEEPVDAIDRSADAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ08</accession>
    <name>C7PZ08_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784859.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0628"/>
    <dbReference type="EnsemblBacteria" id="ACU69564">
        <property type="protein sequence ID" value="ACU69564"/>
        <property type="gene ID" value="Caci_0628"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0628"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017311_0_1_11"/>
    <dbReference type="OMA" id="FDCDWGN"/>
    <dbReference type="OrthoDB" id="1177619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982713" description="Beta_helix domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="123"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="694" mass="70162" checksum="2D3ADB197E2B1F75" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ28</accession>
    <name>C7PZ28_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0648"/>
    <dbReference type="EnsemblBacteria" id="ACU69584">
        <property type="protein sequence ID" value="ACU69584"/>
        <property type="gene ID" value="Caci_0648"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0648"/>
    <dbReference type="eggNOG" id="COG2331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136025_4_2_11"/>
    <dbReference type="OMA" id="RYEYRCR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="1">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="7446" checksum="D8B8CE06AD04DAC3" modified="2009-10-13" version="1">MIRGMARYEYRCRACGDTFELSRPMSEASAPAVCPAGHDDTVKLISAVAVNVGGGTKTAAASGNAGGCCGGGCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA6</accession>
    <name>C7PZA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786856.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2647"/>
    <dbReference type="EnsemblBacteria" id="ACU71563">
        <property type="protein sequence ID" value="ACU71563"/>
        <property type="gene ID" value="Caci_2647"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2647"/>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047963_1_1_11"/>
    <dbReference type="OMA" id="SAPWLEM"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022128">
        <property type="entry name" value="FhaA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042287">
        <property type="entry name" value="FhaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12401">
        <property type="entry name" value="DUF3662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="163"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="25360" checksum="303384C366705678" modified="2009-10-13" version="1">MAMLDRFERRLENLISGGFARAFKAELVPAEIAAELRRECDDTVVVRGQGRSVAANDYVVQMAPEDFTRLAPYATELATQLNDAVRAHVNEQRYLLVGPLAVRLEAAEDLAVGVCRVRSVTLPANQPSGPSPQGPQSPQSPRQASAPWLEMNGTRIPLSTRQIILGRSPDADVRLHDPGVSSRHAVIRLGRSATIQDLDSTNGTFVDGRRVRNADLHDGAVIVLGGVRVTFHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZK7</accession>
    <name>C7PZK7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4661"/>
    <dbReference type="EnsemblBacteria" id="ACU73522">
        <property type="protein sequence ID" value="ACU73522"/>
        <property type="gene ID" value="Caci_4661"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4661"/>
    <dbReference type="eggNOG" id="COG4129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021959_0_0_11"/>
    <dbReference type="OMA" id="NRQNRAV"/>
    <dbReference type="OrthoDB" id="258092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="776" mass="80930" checksum="685A3370088DF7FF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
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        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Caci_4674</name>
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            <taxon>Actinobacteria</taxon>
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    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4674"/>
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        <property type="gene ID" value="Caci_4674"/>
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    <dbReference type="OMA" id="WGIWVLI"/>
    <dbReference type="OrthoDB" id="2057904at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14978" checksum="38B4BE66E0FEE524" modified="2009-10-13" version="1">MIEGEQLTQTDAGARYDVFHTDCAARAVVDHVTSRWGVWVLIALQKHDLRFFELRESIEGISEKMLAQSLRALVQDGLVWRHVEPATPPQVTYGLTDFGRDVGEPLAELFCRITRRSPADSPAERRLALTSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZR3</accession>
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        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4717"/>
    <dbReference type="EnsemblBacteria" id="ACU73578">
        <property type="protein sequence ID" value="ACU73578"/>
        <property type="gene ID" value="Caci_4717"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4717"/>
    <dbReference type="eggNOG" id="COG4214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_0_11"/>
    <dbReference type="OMA" id="FDVWNKR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
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            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="42537" checksum="3D2A0B9AA707FC6B" modified="2009-10-13" version="1">MSSIAPPSKTELAAPTGSGPARRFEINLRASGIYLAFAAIVVLFDILTHGLLLTPENVSNLIVQNSYILVLAIGMILVIIAGHIDLSAGSVVAVTGAIAAVLMVNHHMAWPLALLITLIAGAAIGAWQGYWVAYFGLPAFIVTLAGMLVFRALTMTVLGNQGIGPFPDQVRTLSTGFLGNVLGNVGLGSLGGADLFTLVIGVLAVLAGVASQWRARTAKLRYGQQVESVALFAGKMALMAFVVLGVVVQLARYKNLPWVLVLLTILVLGYSLVASRTVFGRHVYAIGGNAQAAVLSGVKVKKVTFWIFVNMGVLAAIAGVVFAGRLNQAGPTAGTNFELDAIAAAFIGGAAVTGGVGKVVGAITGGLIMGVINNGMSLLGAPSERVMLVKGLILLAAVAFDVWAKRRAGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZU9</accession>
    <name>C7PZU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <end position="128"/>
        </location>
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        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU73614.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="23359" checksum="95E8CF4C52766E63" modified="2009-10-13" version="1">MPAERTDPERTDPLAPHPERDAVLDTAALRVLAHPMRLSFLHYLRDHGPATGRRLAAHFGLDSGAVSYHLRKLATGGLIEEDVGRGTRRDRWWRVTRQALYHDPATREGDDSRAYLHSTLLAYSDALRRYTADVPHLSQAWLNVTMTSERSLRLTPDQLTDLKRDLVAVIDRYRDLPEQPDLPDLPEQPAAQPVSVHIHALPPPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZX1</accession>
    <name>C7PZX1_CATAD</name>
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        <submittedName>
            <fullName evidence="4">von Willebrand factor type A</fullName>
        </submittedName>
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        <name evidence="4" type="ordered locus">Caci_4775</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
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                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
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            <dbReference type="PubMed" id="21304647"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="gene ID" value="Caci_4775"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
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            <end position="612"/>
        </location>
    </feature>
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            <begin position="1"/>
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    </feature>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU73636.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="615" mass="61766" checksum="B992560CF976ABC4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0B7</accession>
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        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
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        </lineage>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8634"/>
    <dbReference type="EnsemblBacteria" id="ACU77450">
        <property type="protein sequence ID" value="ACU77450"/>
        <property type="gene ID" value="Caci_8634"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8634"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028177_0_0_11"/>
    <dbReference type="OMA" id="ANWYWIT"/>
    <dbReference type="OrthoDB" id="525192at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="35"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="706" mass="74319" checksum="DCAC760EB2D5B95C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q115</accession>
    <name>C7Q115_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2777</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786983.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2777"/>
    <dbReference type="EnsemblBacteria" id="ACU71690">
        <property type="protein sequence ID" value="ACU71690"/>
        <property type="gene ID" value="Caci_2777"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2777"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="VLATHEM"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27743" checksum="E1F762FC145F4459" modified="2009-10-13" version="1">MSTEALDANALLRLRGVHKRFDDRTVLDSIDLDVAAHQVVCLIGGSGSGKSTLLRCVDLLVEVDDGTIHLGATELTDPALDQRLARRRIGVVFQAYNLFPHLSVLDNVALAPRRVLGRSRDQAESEAMALLTRLGLADKARDYPDRLSGGQQQRAAIARSLATEPEVLLFDEITSALDPELVGEVLDVVADLKDRGFTILMATHEMDFARHAADQVCFLDNGVIRERGEPDQILTEPREAATQRFLARLLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q179</accession>
    <name>C7Q179_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2845"/>
    <dbReference type="EnsemblBacteria" id="ACU71754">
        <property type="protein sequence ID" value="ACU71754"/>
        <property type="gene ID" value="Caci_2845"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2845"/>
    <dbReference type="eggNOG" id="ENOG502ZMQA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1913300_0_0_11"/>
    <dbReference type="OMA" id="PNIAEPI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14970" checksum="56B3FF22B26E56EE" modified="2009-10-13" version="1">MADIEVKLSGPVFDGRAIESMRRMSEEIQKEIATYAEDSWQSFMDASFRHSTGRYQLFVNVARRDKDLVVNDGWPESHLQYGPWLEGVGSRNSPVTRFPGYFALKRAADHTESDVPNIAEPIVTNYVAEANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q199</accession>
    <name>C7Q199_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787067.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2865"/>
    <dbReference type="EnsemblBacteria" id="ACU71774">
        <property type="protein sequence ID" value="ACU71774"/>
        <property type="gene ID" value="Caci_2865"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2865"/>
    <dbReference type="HOGENOM" id="CLU_2367707_0_0_11"/>
    <dbReference type="OrthoDB" id="1076123at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="95" mass="10427" checksum="EBD619C80D259DBF" modified="2009-10-13" version="1">MTIMHGDPPDEGAVYLDDDHAYVLAYMPDGIELAGITEWHCTAAGDWCAGFVPFKPHNPEYGWDVISLDPLHIEPSLLCRACGSHGFIRGTWIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1B8</accession>
    <name>C7Q1B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4786"/>
    <dbReference type="EnsemblBacteria" id="ACU73647">
        <property type="protein sequence ID" value="ACU73647"/>
        <property type="gene ID" value="Caci_4786"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4786"/>
    <dbReference type="eggNOG" id="ENOG5034A5P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_989340_0_0_11"/>
    <dbReference type="OrthoDB" id="1615114at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30730" checksum="33DD659824E3632A" modified="2009-10-13" version="1">MVIAGPAGEDAAPLETFKDSLVSAANAIAEELARAGRQGRLAEVEKGILERYVKRSKLARQRFIKAGGSASVMLALEEFHQADVEFEQVLAPEVAALLAAYVEANGQKWLSESDATIIGGSLETTGAALLAAGLPLFAENAFRQAGTLYRRFNDSSGEDRCKYLAAAAHRVSLPRWSGKRLLADLQAVLFGYGYRPLRLLVWILVLVAGFTVWLLALPRTGGANESEAFYVAVQNFVNPMGLGDVRLLSGPWKPVLEIETYTGDVFRNLFFVLLIRRLFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1R0</accession>
    <name>C7Q1R0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NLP/P60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6766"/>
    <dbReference type="MEROPS" id="C40.007"/>
    <dbReference type="EnsemblBacteria" id="ACU75611">
        <property type="protein sequence ID" value="ACU75611"/>
        <property type="gene ID" value="Caci_6766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6766"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034085_1_2_11"/>
    <dbReference type="OMA" id="MYVGDGW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982701" evidence="3">
        <location>
            <begin position="45"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="236"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="36977" checksum="EB6139E7CE195A5E" modified="2009-10-13" version="1" precursor="true">MVTSPKEAAHRAPKKYVPVSRTAMTVTLATAAAGSVALLPTAEADPNANINDVKAQVDKLHQEAEQASEAYNEANTSLSDLQHKVDQLQSRITAEQGSLDSARGALGGLAAAQYESGGIDSALQLMLTQSPDQYLQQATSLAQVTDSKKATMSSAAEIQRQLNQDKASASDELAMLAKTRTVMGQQKADIDAKEKQAKDLLNQLTATQRAQYNRMVSNSNSGVSKSTISNLPVPTDARAAIAVAFAKAQVGKPYIWAAAGPNAYDCSGLTMAAWGKAGVAMAHGSRDQYAAFPKVSKSQLQPGDLVLFYSDMHHIGIYVGDGMVIHAGNPASGVQYIPMNEMPAVGFVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S2</accession>
    <name>C7Q1S2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795352.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6781"/>
    <dbReference type="EnsemblBacteria" id="ACU75623">
        <property type="protein sequence ID" value="ACU75623"/>
        <property type="gene ID" value="Caci_6781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6781"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_11"/>
    <dbReference type="OMA" id="MHRRPPG"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="164"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="23417" checksum="1519F55EF6E3B07A" modified="2009-10-13" version="1">MSVLVDNTANLIAYRPARLTAMVVVADPRVRQSVTRHLWALGVRDVLEAQTAAEARSRMSATRDLAVVDIHLPDGSGLQLLAEMRAAGWAGGLAVSAADDAGAVRAALASGVRGFVITGARPVAAGRPGMTGVHAASANRVRPAGGLPPGAAALAGAGGAAQAAHAGCRDLSAREIEVLRLVADGRSNKAIGQAMGLSALTVKSHLARIARKLGTGDRAGMVAVALRGGTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1X2</accession>
    <name>C7Q1X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795401.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6832"/>
    <dbReference type="EnsemblBacteria" id="ACU75673">
        <property type="protein sequence ID" value="ACU75673"/>
        <property type="gene ID" value="Caci_6832"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6832"/>
    <dbReference type="HOGENOM" id="CLU_2315150_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982707" evidence="2">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10542" checksum="F3A0815B23B2616F" modified="2009-10-13" version="1">MLVKAAKVGLALGVVLVIVAAYSLYKGSSAAPTCDGRQMSATDKCITHYADGHTVTQDYTQAKHYDAGLAWVLLIAGIAVAATSATGWQRRRGYRLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1X7</accession>
    <name>C7Q1X7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795406.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6837"/>
    <dbReference type="EnsemblBacteria" id="ACU75678">
        <property type="protein sequence ID" value="ACU75678"/>
        <property type="gene ID" value="Caci_6837"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6837"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1217789_0_0_11"/>
    <dbReference type="OMA" id="STHNINW"/>
    <dbReference type="OrthoDB" id="1629551at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="109"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25865" checksum="23EE0252C26A109B" modified="2009-10-13" version="1">MPSVETCEAVQTCWFTCRAAVLGGRSWTDGPLLWTREGDAQNLMFPERIPADAVKRAVEQARETGVRIIGAWLGAETDTSALAAAGFERGWEPWWMTAPVADVGAASDPRIELLQETVDYKGEYAAYAETLKVTRVRPQHTWYAAAYDDRKGRRFAGRAWSHLSGETAGVFDMNVWPQFQRRGLGSGLLRAVVAAAAEAGASNAVMNATPEGKLLYESCGFRQIGVGITWWLHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q200</accession>
    <name>C7Q200_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77537">
        <property type="protein sequence ID" value="ACU77537"/>
        <property type="gene ID" value="Caci_8722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8722"/>
    <dbReference type="eggNOG" id="ENOG502ZG3V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529905_0_0_11"/>
    <dbReference type="OrthoDB" id="2073397at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980537" evidence="1">
        <location>
            <begin position="18"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="18531" checksum="8C157496406C9A45" modified="2009-10-13" version="1" precursor="true">MALAVLASTVTTGVAFASSATADSVGTGAMSGRVCMFDAPKGALDLGHVAWAFRWSDGSGTWDYGATLQDHNWEKHGSEQQMLQDFATTDDSGGYQSYRCKDTAADDQGAAEAAVTAGFARPYNVIEDNCLTRSVQIFKAYDGSGGLNGLPDGKLVFPNAYFNYNLSGWDDAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q202</accession>
    <name>C7Q202_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797263.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77539">
        <property type="protein sequence ID" value="ACU77539"/>
        <property type="gene ID" value="Caci_8724"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8724"/>
    <dbReference type="HOGENOM" id="CLU_186976_2_0_11"/>
    <dbReference type="OMA" id="DSKIHGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035172">
        <property type="entry name" value="DUF5302"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17227">
        <property type="entry name" value="DUF5302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="7603" checksum="752E8E1921122C69" modified="2009-10-13" version="1">MDTTAAGSQSEPGEPGGGPEAASDADEQKRRFLEALEAKRGNGARGNGGGPGDSKIHSAHGRAGAKRQFRRKSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q239</accession>
    <name>C7Q239_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative nonspecific lipid-transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797300.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8761"/>
    <dbReference type="EnsemblBacteria" id="ACU77576">
        <property type="protein sequence ID" value="ACU77576"/>
        <property type="gene ID" value="Caci_8761"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8761"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035425_2_0_11"/>
    <dbReference type="OMA" id="HGMVNYW"/>
    <dbReference type="OrthoDB" id="647502at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="40827" checksum="822D2AE9CA6E3D0D" modified="2009-10-13" version="1">MNPTPLKDRAAIVGIGQTEFAKHLEPSEKALACRAIAMALDDAGIAAHEVDAFAAYTMEATDEVEIAKAVGAGDVTFFSRVGFGGGGSCATVGHLAMAIATGQASVGVAWRSRKRGSGPRPWTDTVNQLATPAQWTRPFGLLRPVDEIAILARRYMHEYGLTREQLGAVAIACRNRANANPAAIMYDRPLTLDDYLSARMISDPLCLFDNCLETDGALAVVMVSAERARDCRQAPVYVHAFGQGLPAQHHGMVNYWNDDPLAGPSWIAAKQLWKHSDLGPADVDVAQIYDAFTPLIPLSLEGYGFCGKGEGGAFADDGGLELAGRLPINTSGGGLSEAYVHGFNLINEGVRQLRGTSTNQVDGASTCLVTAGEAVPTSAVLLRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2I0</accession>
    <name>C7Q2I0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0889</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785117.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0889"/>
    <dbReference type="EnsemblBacteria" id="ACU69822">
        <property type="protein sequence ID" value="ACU69822"/>
        <property type="gene ID" value="Caci_0889"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0889"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="MIALFSW"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="94"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="31972" checksum="D9B89C22C8C7837C" modified="2009-10-13" version="1">MTPKTSGTPRASRTPKTSQRAKASRRKPQSLPMRIATGVVWVVVAADIALIGWILLTSLRDGTDILNHPFGVPTHPKFGNYSKVFSDGGFGQAALNSVLVAVLSSVLAVVVAAPCAYALARRRNRVSGAMSMTFAMGLGVPGQVMVVPLFIGMAKANLDDSQPGLILVYLGLAMPFTVYLLTGFFSGIPQVLEEAAVLDGAGALRTFTKVILPVARGGLITAFLLQFISAWNETLFAIVLTHSQDKVTLPVALSNFVQEAQLNGLDWGAMFAGVCVVLAPMIALFSWLGSRIIQGMTVGIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E3</accession>
    <name>C7Q3E3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6869"/>
    <dbReference type="EnsemblBacteria" id="ACU75708">
        <property type="protein sequence ID" value="ACU75708"/>
        <property type="gene ID" value="Caci_6869"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6869"/>
    <dbReference type="eggNOG" id="COG4134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_722939_0_0_11"/>
    <dbReference type="OMA" id="WDINPRA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="44069" checksum="D7DD9E0737CC197E" modified="2009-10-13" version="1" precursor="true">MPEISGNGSTSHIPAPSRRNVLTAFAAAGAAAPLLAACSSPSSPGAGTTAKAPASLGGTPSAPVTLNILDVAGNLALTKPMIEAFKTAHPEVVSHLTYSTGTAPQLASKVQAQQQAGNVQIHLVLTGTDGLAAGIQNGLWTGLKPYYDTFFPGLMTDYQPAAAAMTSLAQDQGIELTWYPSGPLLEYDPAKVASPPATTDALLDWAKANSGKFQYARPANSGPGRTFLMGLPYLLGDSDPTDPVNGWSRTWAYLTELGKHVDSYPSGTTAVMKNLAAGSVHLVATTTGWYINPRALGTVPPSMKVAKFTSFTWVSDAHYGVVPKGVSADVLTAVLRLLAWMLTPEQQAFAYDAGYFYPGPAVKNVPLSKAPADSQKVIAQFGEPQFDAWMDQFPIKNSLPAATQVTAFDLWDRKIGSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3H6</accession>
    <name>C7Q3H6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795469.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6904"/>
    <dbReference type="EnsemblBacteria" id="ACU75741">
        <property type="protein sequence ID" value="ACU75741"/>
        <property type="gene ID" value="Caci_6904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6904"/>
    <dbReference type="eggNOG" id="COG2182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_1_11"/>
    <dbReference type="OMA" id="NGPWQIP"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="41788" checksum="9E7589E9549EB066" modified="2009-10-13" version="1" precursor="true">MKHSRWAATLVAAGIVAAGLSGCSSSSGGGSSDSLTVQDYYAEPQAGQMKAIYDSCASQLGVKINIVHVASNGLIAKVLQQVSSKTMPDVLMLDNPNVQQIAASGALAPLSQFGITGDGFAKGAVSAGSYNGKLYAVPPVLNSISLFYNKDILSQAGITPPKTWDELAADAKQLTKPGRYGFAFSAANTGEGTWTFLPFMWSNGGDETNIATPQTAQALQYLTGLVSSGSASKSVVNWTQADVNDQFIAGKAAMMINGPWQIPALDKAGVHWASVSIPTREAGQTVVSPLGGETFSVPNTGHSASMKKAAQFVSCLTNDQNEATKAANEDAVPSRTDAAAKFASSNPELASFVSIVADGRSRTAQLGAKWPATETAIYTAVQAAITGEASPQAALQQAQSQISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3K1</accession>
    <name>C7Q3K1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75766">
        <property type="protein sequence ID" value="ACU75766"/>
        <property type="gene ID" value="Caci_6933"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6933"/>
    <dbReference type="eggNOG" id="ENOG5033N7R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1999795_0_0_11"/>
    <dbReference type="OMA" id="MEPISMI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="12875" checksum="D7E4761A429AAE9D" modified="2009-10-13" version="1">MDPATLVVQALVTGASAGLGDTATAAVSDGYSALKHVLVRRLSGRREALAQLQAIEGGSGGSTDELVHELVVAGAVDERLLADARRLLALTDPEGSTSGKYQLDLREARGVQIGDGNTQHNTFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3N0</accession>
    <name>C7Q3N0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795523.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6965"/>
    <dbReference type="EnsemblBacteria" id="ACU75795">
        <property type="protein sequence ID" value="ACU75795"/>
        <property type="gene ID" value="Caci_6965"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6965"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="AQQCHRI"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="248" mass="25972" checksum="E8A4EA1B039D4213" modified="2009-10-13" version="1">MTNAPMIDLRGTTKKYDDGPPALAGVTLSVAAGECVAILGHSGSGKSTLLNLIAGLDKPSSGTVTVDGTRVDQLGEAGSAKYRRASIGMIFQFFNLLDDLTVLDNVLIPAQLAGMSKGEARRRAVELLGTLGIDRHAKAYPQRLSGGERQRVAVARALMNSPALLLADEPTGALDSSSAEDVRRLLLDLNADGQTILLVTHDVQLAATTAHRIIELVDGAVARDVVTSGRDAAVAVRTTLTRPAGEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R0</accession>
    <name>C7Q3R0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8855"/>
    <dbReference type="EnsemblBacteria" id="ACU77668">
        <property type="protein sequence ID" value="ACU77668"/>
        <property type="gene ID" value="Caci_8855"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8855"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_8_11"/>
    <dbReference type="OMA" id="WQGINLE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982501" evidence="1">
        <location>
            <begin position="31"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="69"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="33540" checksum="63F82119F5124E61" modified="2009-10-13" version="1" precursor="true">MHSRPHSLTRRVAVGVVAVSALLAAGCSSSKSAPAPAAATSSTSPAAAAFPTTVTAKNGAVKLAAEPKKIVSLSPSATEDLFQIGAGSQVVAVDDQSNFPASAPKTSLSGYKPNAEAIAKYNPDLVVVADDSAQIVEQLGKLNVPVLWFDAPNTLDDAYSQITALGTATGHTAAATTEVSSMKQQITAAIAATKKPATPLKYYYEVGTPGNYSATSKTFIGSILSQFGLTNIADPADKTGGGYPQLSDEYLVTAAPDLIFLADTKCCQQTPATTTARPGWSAIPAVKNAPAKHTIVGLDDDIASRWGPRLVGLVQQISQAVNQAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W9</accession>
    <name>C7Q3W9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797451.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8914"/>
    <dbReference type="EnsemblBacteria" id="ACU77727">
        <property type="protein sequence ID" value="ACU77727"/>
        <property type="gene ID" value="Caci_8914"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8914"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_11"/>
    <dbReference type="OMA" id="AYKTVYP"/>
    <dbReference type="OrthoDB" id="1186478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="26673" checksum="EFF6C6A11130E507" modified="2009-10-13" version="1">MKQTYARALVTGASSGFGEHFARQLSARGTALVLVARRGERLEKLAAELGTEIEILPADLTDPVGLAVVEDRLRDAANPVDLLVNNAGVGTTGAFAKLPVEGETGKVALNVMALMRLCHAALPRMTEAGHGGILNVSSLSGTTPAPRAATYGATKAFVTSLSESLNRESRKHGVHVTALLPGPAPTELTEAGFENLLPRLFWQAPEAIVARGLAAVAAGKPVCIPSRALSIATVTGSRMPRSFQYLVGDRLFGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Y1</accession>
    <name>C7Q3Y1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8926</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8926"/>
    <dbReference type="EnsemblBacteria" id="ACU77739">
        <property type="protein sequence ID" value="ACU77739"/>
        <property type="gene ID" value="Caci_8926"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8926"/>
    <dbReference type="HOGENOM" id="CLU_896285_0_0_11"/>
    <dbReference type="OMA" id="DEMAGTK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="33693" checksum="63CD96895F16D569" modified="2009-10-13" version="1">MLLALRPMDSDLEMQLPPLLLWLDEQGRERPSEYIDVSAYAGDEPGAMEFVGMLITILEDRGFVDVVRGLDDRPDSLITKRGKVEAQRVRETRGNRVARMRFARDAVIQWLFAEYPTHAGSQQQFLGWKGSVFLGDMLTNDEFSEAVRYLRGRDLVEVTNLAGTDVRLTTNGIDCATSGGSVSDFLNGPKPQSAGGPVFNAPINGPVAVNSSQFTQNVVTSGAVDIEGLRAFVSLVRDLTPSLTPHESEQQELLSEVSELDIAASTAVPDAGLLKRLTGRVVTAVKGLTHSPGVQKLALEAGEKVLDHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4E0</accession>
    <name>C7Q4E0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4234 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785294.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1074"/>
    <dbReference type="EnsemblBacteria" id="ACU70000">
        <property type="protein sequence ID" value="ACU70000"/>
        <property type="gene ID" value="Caci_1074"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1074"/>
    <dbReference type="eggNOG" id="ENOG5032UXY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135671_0_0_11"/>
    <dbReference type="OrthoDB" id="1674060at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025328">
        <property type="entry name" value="DUF4234"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14018">
        <property type="entry name" value="DUF4234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4234" evidence="2">
        <location>
            <begin position="13"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15735" checksum="F973CCF1014C3624" modified="2009-10-13" version="1">MPQGAVGKKRQPWGVWGLSLITIGIYYYVWWYKVNRETRDFDSRITVNPALSVLAWIPGSYLVIPPFVSAFRTGKRISQAQVAAGLPATCNGGLGILLAILASTHTVYYQGQMNKIWDSYEGAAEGTVVPHRSESVPQGQHIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H9</accession>
    <name>C7Q4H9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787241.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3039"/>
    <dbReference type="EnsemblBacteria" id="ACU71948">
        <property type="protein sequence ID" value="ACU71948"/>
        <property type="gene ID" value="Caci_3039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3039"/>
    <dbReference type="HOGENOM" id="CLU_2153805_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="11938" checksum="059DEF1D62A1CA17" modified="2009-10-13" version="1">MTTFFTSTTVDALNVEIDALIEQILADGRNTCPECGGLCLTPFVDVNPARIPRTDARAQDRIQLFLDRQDLASLPASKYRIDCATPAVAEHTAALLRALGAPARAIHLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Z7</accession>
    <name>C7Q4Z7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyhydroxybutyrate depolymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793674.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5085"/>
    <dbReference type="EnsemblBacteria" id="ACU73945">
        <property type="protein sequence ID" value="ACU73945"/>
        <property type="gene ID" value="Caci_5085"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5085"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_4_0_11"/>
    <dbReference type="OMA" id="ATDTIWQ"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982789" evidence="2">
        <location>
            <begin position="31"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="32607" checksum="6000ABFCC1EF33BE" modified="2009-10-13" version="1" precursor="true">MRRSAFTAAVAAMWLVLATALAGCQSRTHASPVPSSAPVGGSAQSIKIGGATRTFHLYRPHNLPARAPLVVMLHGGFGTGTQAEQDYGWDQEADRDGFVVVYPDGVDHAWNTGGGCCGNPAEQNTDDVGFIKAMIGAIQGEVPIDPSRVYATGISNGGIMAYRLACDTNLFAAIGPDSATLLGTCPAPKPLSVLHIHGSADTRIPYNGGEGEGYAHINGPPVPSVVSTWRTIDSCTPPTTQTKDKVTTSTATCPDARTVELITITGAGHQWPGSPQRPVKKALLGSDTPSTALNATDVFWQFFAAHPKSDASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5E2</accession>
    <name>C7Q5E2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7081"/>
    <dbReference type="EnsemblBacteria" id="ACU75911">
        <property type="protein sequence ID" value="ACU75911"/>
        <property type="gene ID" value="Caci_7081"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7081"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1131997_0_0_11"/>
    <dbReference type="OMA" id="AHEPPDD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="25039" checksum="C83DA9AD13AFBB67" modified="2009-10-13" version="1">MILVRRLLGDVLRGRRQRSGRTLRQLAATARVSPGYLSEVERGQKEPSSELLAAICDALEVKLSDVLLELSTELAAAELAAEIEAAELGSLVPADRRTPQRVAMPPARSGQADAARQGQSQAGSGQRSGVVVGVGAGAPRGTRTIPTAKIPTAVINSRTAGNRPGNTRPASGSPRVAPKSGAVPQATRGTGMGAQGSSLATGLGQALGPQPPMGPLPYVPGSPLPGPENPYTFGTPRLPSPTGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5V0</accession>
    <name>C7Q5V0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2201_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785341.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1121"/>
    <dbReference type="EnsemblBacteria" id="ACU70047">
        <property type="protein sequence ID" value="ACU70047"/>
        <property type="gene ID" value="Caci_1121"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1121"/>
    <dbReference type="eggNOG" id="COG3864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_448267_0_0_11"/>
    <dbReference type="OMA" id="RDPYLFN"/>
    <dbReference type="OrthoDB" id="278539at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025154">
        <property type="entry name" value="Put_metallopeptidase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13203">
        <property type="entry name" value="DUF2201_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2201_N" evidence="3">
        <location>
            <begin position="259"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="608" mass="66198" checksum="67C940BF9A0AFE82" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q690</accession>
    <name>C7Q690_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787389.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3188"/>
    <dbReference type="EnsemblBacteria" id="ACU72096">
        <property type="protein sequence ID" value="ACU72096"/>
        <property type="gene ID" value="Caci_3188"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3188"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="MQYVTAW"/>
    <dbReference type="OrthoDB" id="1225778at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="34570" checksum="3878F059741DA4EB" modified="2009-10-13" version="1">MATTVVFHEYGGPEVLRLVDVPVGEPGPGEIRVRVQAIGLNRAESLFRAGIYIEQARSFPARLGGECAGVVEAVGPGVTGFAPGEEISTVPQFSYNDYAVYAEQAIVPVSAVVHRPHGLDAVGAAAVWMPYLTAYSALADTVGARPGDTVALNAASSSAGLALIDVANHLGLRPIALTRTAEKKDALLKHGAAEVVVTDHENQLDRLLRATGGRGVELVMDAVAGPGVTDLARAVAPGGTLLVYGGLSGQPTPYPGLTLGLPALNMRSFTVLETTRDPERLRRAVAFVAAGVRSGAFRPVVDRTLDLADIAEAHWYLESNAQVGKIVVTVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6G2</accession>
    <name>C7Q6G2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5138</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793726.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5138"/>
    <dbReference type="EnsemblBacteria" id="ACU73997">
        <property type="protein sequence ID" value="ACU73997"/>
        <property type="gene ID" value="Caci_5138"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5138"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852373_0_0_11"/>
    <dbReference type="OMA" id="WIWEAVE"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="128"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="34962" checksum="8A7059997AAE9704" modified="2009-10-13" version="1">MSTATAGTPTDTDTDTALVRAAQTGDVAALALLLEQHRAGMRAVALSILGPGPDADDAIQDAVLVALRRIGDVRDPAAAGAWLRMIVRNQCRGQLRDAQRLVPLDELASHRDSAPGPDELLENHAMQDWLWEAIEQLSPALRLTLVLRHFSEHVTAYDQIARVCGVPAGTVRSRLNQARAKLAAALAATAEAAHSDARTRTAASWDEAHDTLATAEAGEFGRVVAQRWSPDVALMYGGSRLGGSALITRAMDCDLAAGVRQRPVKVIAGRSLAVWEMDITSPPDNPEHCPPTAAWVMDLDGGRVARLRLFHPRPLAESVMEQRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6K7</accession>
    <name>C7Q6K7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5183"/>
    <dbReference type="EnsemblBacteria" id="ACU74042">
        <property type="protein sequence ID" value="ACU74042"/>
        <property type="gene ID" value="Caci_5183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5183"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="OMA" id="RRNVNAM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="574"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="863" mass="90482" checksum="99FC0D925FB75F28" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T8</accession>
    <name>C7Q6T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Caci_7121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="gene ID" value="Caci_7121"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="202"/>
            <end position="224"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU75951.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="26415" checksum="27A69AA22DE33400" modified="2009-10-13" version="1" precursor="true">MRRWEAILGRVKTLPALMLAAGGVGFGHAVMPDHWMPLAVLSRTRRYSTRRTVRLSLAAGVTHVLVSLVLGAVLVVVGLQFRGTVSRHTDGVIGGILLVTGVVFVVMEVAGRGHGHGGGDGHQHTHDHGHARDHGHDHGHVHDHDRGHAHDHGRAHDHGRRDARSLAAFLVPFGAAASPDLTILPVFLAAGAVGVVASIGSLIAFAAVTVATIAGLTTATAAGARLLTAPWIDRGANLLTAGTLLLVGGLVAGGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6U4</accession>
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        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
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    </protein>
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        <name evidence="6" type="ordered locus">Caci_7127</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7127"/>
    <dbReference type="EnsemblBacteria" id="ACU75957">
        <property type="protein sequence ID" value="ACU75957"/>
        <property type="gene ID" value="Caci_7127"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7127"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="DWMGQWT"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="341"/>
            <end position="541"/>
        </location>
    </feature>
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        <location>
            <begin position="227"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="375"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="541" mass="58210" checksum="D615C544B2521DAD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q712</accession>
    <name>C7Q712_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7196</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795753.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7196"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH19">
        <property type="family name" value="Glycoside Hydrolase Family 19"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76025">
        <property type="protein sequence ID" value="ACU76025"/>
        <property type="gene ID" value="Caci_7196"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7196"/>
    <dbReference type="eggNOG" id="COG3179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045506_0_0_11"/>
    <dbReference type="OMA" id="TISTWYW"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981441" evidence="2">
        <location>
            <begin position="38"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="3">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="3">
        <location>
            <begin position="104"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="37785" checksum="47D21AF77AD7EEAF" modified="2009-10-13" version="1" precursor="true">MTLTHAPKRTRLLALLAALASVLGLTLIAMPASPAHAATACAAPWNSGVAYTGGQTASYNGDNWSAKWWTQGDIPGNNGQNVWADQGACSSSGGGGGGGSSCSYPAWVAGQYYNVGAIVTYTPNGGLYIATNANPGYDPTISTWYWSPYTCTGGGGGGGGGGGGSNGFVVSEAQFNQIFPNRNSFYTYSGLVAALSAYPAFATTGSATVQKQEAAAFLANVDHETGGLVYINEIDQSGNYCASESYGCPAGTYAYYGRGPLQLSWNFNYYAAGNALGIDLLDNPNLVATDPATSWKTAIWYWFTGTGNGSLTSHQAMTTGAGFGATIRAINDIECNGGNTGEMQDRVNDYESIAGVLGVTPGGNLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q736</accession>
    <name>C7Q736_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795777.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7220"/>
    <dbReference type="EnsemblBacteria" id="ACU76049">
        <property type="protein sequence ID" value="ACU76049"/>
        <property type="gene ID" value="Caci_7220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7220"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_1_11"/>
    <dbReference type="OMA" id="RARSFTM"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="41722" checksum="E609075FF70E8350" modified="2009-10-13" version="1">MTSRAQKTTRDLRWHNRADLLTRLYLGEATNRNDLARASGLSAATISNVVSDLIGDGLVGENGSQSSAGGRPRSLLRVLPAFGHVVGIDIGETEIRVGLFDWTLHPVAEEARPVDIPRVPPQQVADQVLSEIAAVTARAGIAVDDLLGVGIGVPGAGGSVIHAPTLGWSAVPLAGLLRDRLGFTPDIDNGAMALGQAEAWRGAARGAERAVALLLGTGAGGALSLAAGPGGRARSFTMEWGHTVVDLEGPHCRCGARGCLETYIGAEAILARYAATPGSTPLAEDGVEAQLSELVARASQHHESAALEVLDATATYLGVGISNLINLVAPDRVIISGWAGALLCDAALLPAVRRVVRRHALPYLQEFTRIEPGELGPSATALGAATLPVARLLADGGRREER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7L4</accession>
    <name>C7Q7L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787500.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3300"/>
    <dbReference type="EnsemblBacteria" id="ACU72207">
        <property type="protein sequence ID" value="ACU72207"/>
        <property type="gene ID" value="Caci_3300"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3300"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018576_0_0_11"/>
    <dbReference type="OMA" id="HDQIFLT"/>
    <dbReference type="OrthoDB" id="199988at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="98"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="662" mass="71467" checksum="92B207DB8E9870B5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Y5</accession>
    <name>C7Q7Y5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DhkE HisK family protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793881.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5293"/>
    <dbReference type="EnsemblBacteria" id="ACU74152">
        <property type="protein sequence ID" value="ACU74152"/>
        <property type="gene ID" value="Caci_5293"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5293"/>
    <dbReference type="HOGENOM" id="CLU_1674743_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021527">
        <property type="entry name" value="DUF2795"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11387">
        <property type="entry name" value="DUF2795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="17971" checksum="B6CAE29F66B17B27" modified="2009-10-13" version="1">MTKSKKQFAAEQQPQAPQNQQNQQRQQQRNQQNQNQQQNQNQGQQQRKPKATNEEFGRTVELAFVDHPWPASRGELLEHASRQGTFAKPELARLKQIPHREYHSIADLVEATRQADSMMMAQAPGPVATAEHNRRAMGEMPENAPMHAGSQFDERTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q897</accession>
    <name>C7Q897_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795813.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7256"/>
    <dbReference type="EnsemblBacteria" id="ACU76085">
        <property type="protein sequence ID" value="ACU76085"/>
        <property type="gene ID" value="Caci_7256"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7256"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_5_11"/>
    <dbReference type="OMA" id="TRHGKTE"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23865" checksum="A80D4E0077A1CA04" modified="2009-10-13" version="1">MDRAAHVHGARQVVLWRHGRTAWNLERRFQGQTDIPLDDVGLAQAERAARVLAGLGPSVIVASDLIRATRTAETLARLTNLPVTLDEALRETYAGRWQGLNDDEIVARYPEEFEAFRRGEPIRRGGGELEVEVAERVVPAILRALEKVPPAGTLVVATHGGAARVALGRMMGLPYELWGALGGLSNCCWSILGEARRGWRLLEHNAGTLLEPVIGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8A6</accession>
    <name>C7Q8A6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7265"/>
    <dbReference type="EnsemblBacteria" id="ACU76094">
        <property type="protein sequence ID" value="ACU76094"/>
        <property type="gene ID" value="Caci_7265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7265"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125060_1_0_11"/>
    <dbReference type="OMA" id="AIRIVWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14889" checksum="DDA518B2284D93C9" modified="2009-10-13" version="1">MTNTTENTTVDATEAAAVVDRYIAVWAVADASDRAKAVANLWSDHGIEYIEGQQYIGHAALTDRVAEAHEAFVANATYTATGGDDVAVHADIVTFTIRLDHAQGPDAGETAWSARVFLVLDADGRVREDYQLTVKPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D6</accession>
    <name>C7Q8D6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="4" type="ordered locus">Caci_7295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7295"/>
    <dbReference type="MEROPS" id="S14.008"/>
    <dbReference type="EnsemblBacteria" id="ACU76124">
        <property type="protein sequence ID" value="ACU76124"/>
        <property type="gene ID" value="Caci_7295"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7295"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_11"/>
    <dbReference type="OMA" id="RDYWMKA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="22314" checksum="90C86E7974B0D5E6" modified="2009-10-13" version="1">MTTPLTPMARAGVDSPLGLSDQVYNRLLRNRIIFLGSQVDDDIANSLCAQLLLLTAEDSEKDIYFYINSPGGSVSAGLAIYDTMMYVPNDIVTVGMGMAASMGQFLLTAGTPNKRFALPNTEILLHQGSAGIGGSAADIRIQAERLLRSKKRMAELTAQHTGQTLDKIEKDSDRDTWFSSAEAKEYGLIDDIMTHANDVPGAGGTAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L9</accession>
    <name>C7Q8L9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785578.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1361"/>
    <dbReference type="EnsemblBacteria" id="ACU70284">
        <property type="protein sequence ID" value="ACU70284"/>
        <property type="gene ID" value="Caci_1361"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1361"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_1_11"/>
    <dbReference type="OMA" id="RITLMWC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21528" checksum="CD37A7401EF91520" modified="2009-10-13" version="1">MATVHEVIDAKLRKFIEAQPLFFVATAPLAAEGHVNLSPKGTLGSLAILGPDRLAYLDLTGSGAESLAHLRENGRITVMWVAFEGPPNIVRVHGTGEVLWRDDPRWEEYIGLFPAAADPGARAIVLVQATRISDSCGYAVPFMDYKGDRRLLAEYFGRRDEEFHVDYVARKNATSIDGLPAVPVETLRGQLKSQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M8</accession>
    <name>C7Q8M8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785587.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1370"/>
    <dbReference type="EnsemblBacteria" id="ACU70293">
        <property type="protein sequence ID" value="ACU70293"/>
        <property type="gene ID" value="Caci_1370"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1370"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_3_11"/>
    <dbReference type="OMA" id="VNQFHGA"/>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="4">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="5">
        <location>
            <begin position="261"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="39875" checksum="46B21823CC01A4F8" modified="2009-10-13" version="1">MGEAYIVGALRTAVGRKKGALAAAHPADMGAHVIKAVVDASGVDPAAVDDVVFGCVDTIGHQAGDIARTAWLAAGLPEEVPGVTVDRQCGSSQQAVHFAAQAVLSGTADLVVAGGVQNMSQIPIAAAMTVAGQFGVTDPFSGSRGWRARYGDQPVSQFHAAELIAEKWDVSRDAMEDFALESHRRALAAIDAGRFEREIVPYEGFAVDEGPRRDTSKEAMAGLRTLVEGGRLTAAVSSQISDASAALLIASEDAVRTHGLTPRARIHHLSVRGADPIYMLTAPIPATAHALRKTGMSLADIDLVEINEAFAPVVLAWAKETGADLAKVNVNGGAIALGHPLGATGARLMTSLLHELERTGGRYGLQTMCEGGGQANVTIIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z2</accession>
    <name>C7Q8Z2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diacylglycerol kinase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3406"/>
    <dbReference type="EnsemblBacteria" id="ACU72312">
        <property type="protein sequence ID" value="ACU72312"/>
        <property type="gene ID" value="Caci_3406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3406"/>
    <dbReference type="eggNOG" id="COG1597">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045532_2_2_11"/>
    <dbReference type="OMA" id="NCGLIPG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="32851" checksum="373773585E9C47B9" modified="2009-10-13" version="1">MNQVAIVVHEGKLAALHGEDPCDQLRWALRARGEPAPKLYPTSDSDAGGQAVRKALAEGARLVVVCGGDGTVSSCAAALAGTGVPMAVIPIGTGNLVARNLGIPADPTVAVGVAVSGVDRAVDVGRLGDMPDDASDGASGTSDGTSKGAVMVGMAGVGLDAAMVQDAPHGLKRRIGWPAYVISLLRHLADRGFAVEIDVDGKRTSHRHVRTVVIGNVGGLHAGLSLFPDAQPDNGVLEVAVLAPRTVLGWIPVTARLLRGRDRPPVIARARGRHIVVSGQSVLRREADGEALADGRVLDVTVEPGALLLRVAAETSADAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q900</accession>
    <name>C7Q900_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3414"/>
    <dbReference type="EnsemblBacteria" id="ACU72320">
        <property type="protein sequence ID" value="ACU72320"/>
        <property type="gene ID" value="Caci_3414"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3414"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_264174_0_0_11"/>
    <dbReference type="OMA" id="IAANGCC"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983033" evidence="1">
        <location>
            <begin position="31"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="113"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1407" mass="141904" checksum="4AD161D54FF2C4E9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q977</accession>
    <name>C7Q977_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792126.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3491"/>
    <dbReference type="EnsemblBacteria" id="ACU72397">
        <property type="protein sequence ID" value="ACU72397"/>
        <property type="gene ID" value="Caci_3491"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3491"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="EINYFPN"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="37683" checksum="A0C8F5C0D1F35AC8" modified="2009-10-13" version="1">MTADDDIPRAPTLEDVARVAGVSRATVSRVVNDTRNVDRRIREVVQAAVAQTGYVPNQAARSLVTRRTGSVALVVSEAEHRSFDDPFLGRVFTDPFFGRVVSGIISVLRPRAVNLVLMLAETNDSRSQLIDYLRQGHVDGVLLISTHADDPLPSMLIESGLPTVLSRRPSTPIPISYVDVAQHVGAGLAADRLAERGCQQVATISGPMDMPASQDRLNGFREAMARHGHAFVPSVEGNFTQDSGEQAMRELLDRYPDIDGLFAANDLMAQGALLALHDRGIAVPGRVAVVGFDDSSAATASRPPLTTVRQPIEDMAAAMADLLLAHIDERQPRVTSRIFEPTLVVRDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E6</accession>
    <name>C7Q9E6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794021.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5433"/>
    <dbReference type="CAZy" id="GT87">
        <property type="family name" value="Glycosyltransferase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74292">
        <property type="protein sequence ID" value="ACU74292"/>
        <property type="gene ID" value="Caci_5433"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5433"/>
    <dbReference type="eggNOG" id="COG5650">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034641_3_0_11"/>
    <dbReference type="OMA" id="PRGMLIG"/>
    <dbReference type="OrthoDB" id="1362354at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="45978" checksum="CD47866B867FE023" modified="2009-10-13" version="1">MAMMAGDGPWIHRLTRSSKKPWSRRRAAAWWTAAAVLVFGIGLIAGKGGNPLIDLKVYRDGGISFMKDLPLYTTRFPHPLDGPDLPFTYPPFAAVLFSVLGFVGYHLAAVLMVLIGFTALTWTIYLVLHNRAGARFLPEPTPRVLVTITLLSLVMEPISSTFLHGQINLLLMGLVVTDALGPKTRIPRGALAGVAAAIKLTPAVFLLYFVARRQWKSASNMVAAFIGATSLSIILAPRDSKAYWTATVFDPTRIGDLGYAANQSLRGGLHRLGGLPGLAMSVKTEERLWFALSMIVIALAYHGARRAIRREDPVCALAVVAACQLLISPVSWSHHWVWIAPMLLPFAIQIVRGGERLKIAGLVVLTAVFLIGPLLLFPVDHGLEMHWGWWENLIGDAYLIITLSFVVWAASTRRTPAPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9P7</accession>
    <name>C7Q9P7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795944.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7390"/>
    <dbReference type="EnsemblBacteria" id="ACU76216">
        <property type="protein sequence ID" value="ACU76216"/>
        <property type="gene ID" value="Caci_7390"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7390"/>
    <dbReference type="eggNOG" id="COG0229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_8_5_11"/>
    <dbReference type="OMA" id="DEQWRAE"/>
    <dbReference type="OrthoDB" id="1650261at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="9"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="15206" checksum="900B1F1691A05289" modified="2009-10-13" version="1">MVEKVQKSEAEWRSLLSPMEFAVLREAGTERPWSGEYVSTHTEGTYHCRACDAPLFRSQAKYDSHCGWPSFYEPGEGDAVTLLEDRSHGMVRIEVRCAACGSHLGHVFDDGPREHGGQRYCINSVSLKLDEEPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA47</accession>
    <name>C7QA47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1524"/>
    <dbReference type="EnsemblBacteria" id="ACU70445">
        <property type="protein sequence ID" value="ACU70445"/>
        <property type="gene ID" value="Caci_1524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1524"/>
    <dbReference type="eggNOG" id="COG0758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454699_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="600" mass="61676" checksum="B0C823E3F40854B2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB9</accession>
    <name>C7QAB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72418">
        <property type="protein sequence ID" value="ACU72418"/>
        <property type="gene ID" value="Caci_3512"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3512"/>
    <dbReference type="eggNOG" id="ENOG5033Y3U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_996347_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982670" evidence="2">
        <location>
            <begin position="27"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="27450" checksum="73EF5502CED9F8E7" modified="2009-10-13" version="1" precursor="true">MGCTVATTLVVAVTACSSGGSGKASAAAATTANDTSSSAPTTPPASTNTPTNPPSTTESAASTSASVPTAPPTSVPSTSASLSQTSGAYLKTLLPVSGTEALLSLGPTLPPGWTAATARELDSGPTPKPPAPSLIDGDDCTYLVKQSPTLDLAEGLSVANASEGLTSTTTSASLIIYAYAPGDAAKSLAQVRQNLASTCNGFTAMLNTGAVHVDVAATPVSNLGDEALLVKITPDGPYVDAENLVVRHGNVTLSLFANNELAPLPDLSPVAAALIGGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAI5</accession>
    <name>C7QAI5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792213.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3579"/>
    <dbReference type="EnsemblBacteria" id="ACU72484">
        <property type="protein sequence ID" value="ACU72484"/>
        <property type="gene ID" value="Caci_3579"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3579"/>
    <dbReference type="HOGENOM" id="CLU_1292497_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22576" checksum="CEB5A627A8C747FA" modified="2009-10-13" version="1">MADRGESVLDDPRRLRPATIATVVVILGVVAALVIPVLLCVRGWHEAETFRGVGAGRGIFVAESCGDRQVHKSADANGATLTTVTYTCAGTFDGRSGVRIDAAVGDASHDYRAGARTPAYVTGKGVVRLASNHDAAVWMALWFFVACVVAAAEGAALWLLSRWIRGTVPHGVRELMDWPHLLAASLVGLLAVIPGLMILYLLAFLSLLILYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB00</accession>
    <name>C7QB00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5614"/>
    <dbReference type="EnsemblBacteria" id="ACU74473">
        <property type="protein sequence ID" value="ACU74473"/>
        <property type="gene ID" value="Caci_5614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5614"/>
    <dbReference type="HOGENOM" id="CLU_1458813_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980777" evidence="2">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="18993" checksum="BAAACD3B27B4B290" modified="2009-10-13" version="1" precursor="true">MSIRRFRRALAVGMTLVGAALLGAGPVSASGTGSGSTGTGAVPGRTAGAPAAPTPSPMAITVCHDHGTYLGLGLHRLGTGKNLLVVEVCGDAAKRTVSMVRDSYLKVDGPRAGSLRFHWRWADKTGAVKGGGDDDNGAFVLDPQSENTFAWPYSQPVAPMAPTARCVVGVLTEGSTQFVTEPVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB60</accession>
    <name>C7QB60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796076.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7526"/>
    <dbReference type="EnsemblBacteria" id="ACU76351">
        <property type="protein sequence ID" value="ACU76351"/>
        <property type="gene ID" value="Caci_7526"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7526"/>
    <dbReference type="eggNOG" id="ENOG5031D4Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048736_0_0_11"/>
    <dbReference type="OrthoDB" id="1885057at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="411" mass="43878" checksum="C6D27EFC12DA1C63" modified="2009-10-13" version="1" precursor="true">MSTDTKIVVGVVVTGLSACLAAVAAHVGWSFWPALLGIPLVFAAVAVGSHPGGRSYDAKSGDDASYNGFAPSASSWTDGGLTVSPPLSVMLPGVEHECPQPRMRLRSAADGYDFRFAATVRWRESANMSPVAHSDLAAVARSAIIRRAADLLASRDPGEVALVEAELAGALGARLSDATGLLEAWAGDVSLTLSDADSERMRRLTEIRKDEQVWESEREYEKHRRAYLGGDVLKSAGSAVVWALARKEDSIERAVDLIGPLALLSAAANDTDVAPVFRHLVAPEFAAQNGHVPSPPDASNDYDNYGDDDDHADPEPARANGVPRTTPDYIAEMADHLGFTSSDHRNLFVGNIVNVLKSMERPDDAESVRRAFYPQQDLDEPLFDVGEPAPAASVADGPVAGSNEFYDPYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC35</accession>
    <name>C7QC35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3752"/>
    <dbReference type="EnsemblBacteria" id="ACU72654">
        <property type="protein sequence ID" value="ACU72654"/>
        <property type="gene ID" value="Caci_3752"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3752"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="PNAYELR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="245"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="992" mass="107017" checksum="D44BAC5C8A71B436" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC72</accession>
    <name>C7QC72_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794249.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5661"/>
    <dbReference type="EnsemblBacteria" id="ACU74520">
        <property type="protein sequence ID" value="ACU74520"/>
        <property type="gene ID" value="Caci_5661"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5661"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_1_2_11"/>
    <dbReference type="OMA" id="DIKGRME"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01095">
        <property type="entry name" value="Nitrilotriacetate_monoxgenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="147"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000337-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="467" mass="51010" checksum="F714A34126F12DBE" modified="2009-10-13" version="1">MPARAPRRLHLNAFLHAPGHHDAAWRHPDSGGHRALDVDYHIDLARTAERGLFDAVFLADTLAVRGRPDATVAAGLEPLTLLTALATATEHIGLIATASTTFYEPYILARTLASLDHISHGRAGWNVAAGGDLAEAANFNLDEPIEHTVRYERAAEFLDVATQLWDSWADDAVVHDRRAGRYADPQRVREVAHTGLFFKVRGPLNVQRTPQGWPLLVHSASSAEGQEFAARYAEVVLTGQQNLGDAAAFALEVKSRAAAYGREADVPVIMPSIAPVIGSTETEARRLARELTELHLAEPGVNQLSNLLGIDVAGLDPERPIPAGLLPREEDLADHRFARSWPTTTTQLTDLAIRERLTVRQIVARLGGGRGHRTVVGTPEQIADSMQEWSQAGAADGFTIAPPILPSGLTTFVDQVVPLLQRRGLFRTEYDLGTLRERFGVERPEDHFPEPTPATPRRTARPPLARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA2</accession>
    <name>C7QCA2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794279.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5692"/>
    <dbReference type="EnsemblBacteria" id="ACU74550">
        <property type="protein sequence ID" value="ACU74550"/>
        <property type="gene ID" value="Caci_5692"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5692"/>
    <dbReference type="HOGENOM" id="CLU_1515247_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981540" evidence="1">
        <location>
            <begin position="35"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18420" checksum="434F735656BEF1BE" modified="2009-10-13" version="1" precursor="true">MTEVSRRDLFKRSASVAATATVASVVVGESSASAATGSAGRARTFIGTVVRQDGSGLVVTAPKEHGDSVLVRPEGFPPGWVFRSGDKVTVMAGRPGLPQSAVPLLQEVSGRVQGYSQAGGVESFTVDGITVTLHETTAVLDTSPKEAAASRDSRRFLLGYTENVDGHKTAFGFRLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCB9</accession>
    <name>C7QCB9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="5">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trpA</name>
        <name evidence="7" type="ordered locus">Caci_5709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794296.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5709"/>
    <dbReference type="EnsemblBacteria" id="ACU74567">
        <property type="protein sequence ID" value="ACU74567"/>
        <property type="gene ID" value="Caci_5709"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5709"/>
    <dbReference type="eggNOG" id="COG0159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016734_0_0_11"/>
    <dbReference type="OMA" id="LVMTYWN"/>
    <dbReference type="OrthoDB" id="912786at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="27885" checksum="DB876624DA732D4C" modified="2009-10-13" version="1">MNRLQDVLKSARADNRAVLIGYLPAGYPSVDGSIDAMRAMVEGGCDIIEVGLPYSDPAMDGPVIQAAADQALSRGVTTPDVIRAAGAVADTGAAALIMSYWNPIEHYGVERFAAELAAVGGSGVITPDLIPEEAGPWVAATDAHDIGRVFLVAPSSTPERVALTTEVCNGFVYAGAVMGVTGARDQVGHAARDLVERTRKATDQAVCVGLGVSTGDQAAEIAGYADGVIVGSAFVRRLLDNRDPRKGVEAVRELAAELADGVRRGSKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCE0</accession>
    <name>C7QCE0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Histidinol dehydrogenase</fullName>
            <shortName evidence="10">HDH</shortName>
            <ecNumber evidence="5 10">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hisD</name>
        <name evidence="17" type="ordered locus">Caci_5730</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11 16">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794317.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5730"/>
    <dbReference type="EnsemblBacteria" id="ACU74588">
        <property type="protein sequence ID" value="ACU74588"/>
        <property type="gene ID" value="Caci_5730"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5730"/>
    <dbReference type="eggNOG" id="COG0141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_3_1_11"/>
    <dbReference type="OMA" id="MVTGPGN"/>
    <dbReference type="OrthoDB" id="935289at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 14 15">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="47005" checksum="C981EB4199DCBAB7" modified="2009-10-13" version="1">MITRIDLRGRALDTDQTDPRALVPRAELDVEAALAVVRPIVEDVRHRGEAALIDYAAKFDGVELTEVKVPAAALAEALERLDPQVRAALEESIRRARTVHRDQRRQDTTTQVVPGGSVTERWVPVDRVGLYVPGGRAVYPSSVVMNVVPAQEAGVGSLAVASPPQKEFGGLPHPTILAACALLGVDEVYAAGGSQAIAMFAYGYREAAEGAEAQGAVVCRRADLVTGPGNIYVAAAKRLLKGVIGIDAEAGPTEIMVVADASADAGVVAADLISQAEHDPLAAAVLVTDSEQLAEEVVKELETRVAATKHAERIREALAGRQSALVLVDDIGAALVVANGYAAEHLEIQTRNAAADAAKVRNAGAVFVGSFAPVSLGDYLAGSNHVLPTGGCACHSSGLSVQSFLRGIHVVDYTREALAEASDLVVALANAEDLPAHGEAVTARFEERQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDI7</accession>
    <name>C7QDI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5753</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5753"/>
    <dbReference type="EnsemblBacteria" id="ACU74611">
        <property type="protein sequence ID" value="ACU74611"/>
        <property type="gene ID" value="Caci_5753"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5753"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_2_11"/>
    <dbReference type="OMA" id="NWRPTFW"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="4">
        <location>
            <begin position="2"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="34364" checksum="C61A4A97243A5C21" modified="2009-10-13" version="1">MLTVIGEALIDLVPAGEPGGYRARPGGSPLNVAIGLARLGHRTALMARLADNAFGRLLREHAASEGIDLTCAPWATEPTTLAIVSLDSDAQASYDFYLDGTADWQWTDAQTAALPEDTTILHHGSLASWTPPGDERIHALASELHRHGSVLISYDPNIRPALLGKPSHARPLIERNVGVSHIVKASRDDIDWLYPGHGPEHVGAAWIDLGAQLVIVTDGPRGAHVFRSAAAPAHRPGRAVQVADTVGAGDAFTAGLLGALVRNGVQTPDQLRQATPQLLDNAVDDAILVSALTCERVGADPPMALPRPHTPPSTPLSAADLGFRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDJ0</accession>
    <name>C7QDJ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5756"/>
    <dbReference type="EnsemblBacteria" id="ACU74614">
        <property type="protein sequence ID" value="ACU74614"/>
        <property type="gene ID" value="Caci_5756"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5756"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_0_2_11"/>
    <dbReference type="OMA" id="YTQDFVK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="356" mass="36642" checksum="9EBAD77F5D6AA264" modified="2009-10-13" version="1">MQTTDTDHEGTPVSIHAEHRTAAASAEGLLNRPPTPGQRVHAVLHRQPALSPAIVLLLAGVTFALLNDRFYRLENLSLVAQQVAVVGSLAAGQTLIILTAGIDLSVGAVMVLSSLVMAKLVSDQGVPGVVALLVGACVAVAAQAVNGLLVTKIKLPPFIVTLGTLSIFTAATLIYAKGQTIALHPDAFLLWSAKPVSIGSLHLTTGVLMMAVLYAVISFALRYTSWGRHLYATGGDPEAARLAGISVNRVLLSAYMVAGIAIAVAAWILVGRVGGGDPNSGLNANLESITAVVIGGTSLFGGRGVVLGSLIGAFIVQVFDNGLALAGFDPNYQVLAVGVLVIAAVSVDQWIRSVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDS0</accession>
    <name>C7QDS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794423.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5836"/>
    <dbReference type="EnsemblBacteria" id="ACU74694">
        <property type="protein sequence ID" value="ACU74694"/>
        <property type="gene ID" value="Caci_5836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5836"/>
    <dbReference type="eggNOG" id="ENOG5033SC4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1056432_0_0_11"/>
    <dbReference type="OrthoDB" id="2121688at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="28212" checksum="A8FA8E5CD6233A93" modified="2009-10-13" version="1">MALIETSDGYTLWYDAVGPWDAAGIVFPVRHRGEFAALGTALAETYRVVRYKPRRVVGEVEDEPGAGGTWQGPDFTEYPTQMEVADLHAVADAAGLDGFVLAGYSGMAALAGFLAPLSDRTRGLLVGGFPLLADFDYWLGFEEGARAALVQAGLPDKAGDHHMGHLMFRQWAARDARDDRAALAALPGPKILWHGSQDCEPECRAFDPAGGTAIGRHNHADEPELRDLGFEVIEVAGHDHIGALAQIDVVLPQLAEALAGSKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE80</accession>
    <name>C7QE80_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796393.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7844"/>
    <dbReference type="EnsemblBacteria" id="ACU76668">
        <property type="protein sequence ID" value="ACU76668"/>
        <property type="gene ID" value="Caci_7844"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7844"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="25502" checksum="9530AE387D92956B" modified="2009-10-13" version="1">MERVSIITGGGRGIGRATALRLARDGHDIAFSYLSDDAAAEETAAEVRDLGRRCVAVKMDTTDEADVDRLFDTAIGELGGLTGLVNNAGLTGPLTRLVDADVADIRRVVDVNVVGYLLCCRRAAKELSSRGGGAIVNVSSGAATRGAPNEYVHYAAAKAAVDSFTVGLAQELGREGIRVNSVQVGITRTRIHADMGDPDRAEKRGALTALGRPAEPEEIAAAIAWLLSDEASFTTGAVLRVAGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG3</accession>
    <name>C7QEG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1934"/>
    <dbReference type="EnsemblBacteria" id="ACU70854">
        <property type="protein sequence ID" value="ACU70854"/>
        <property type="gene ID" value="Caci_1934"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1934"/>
    <dbReference type="eggNOG" id="COG5607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026984_0_1_11"/>
    <dbReference type="OMA" id="REATWNA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29894" checksum="B68234966E128EB7" modified="2009-10-13" version="1">MTHGMSLLTSLQSKADALATLEPDVRADAPDAVHQMRVAARTLRANLRTFEDVLPSTKKRLGLIEELGWLGDALGPAREAEVLAELVLDLLKRTPSEYVLGPVKQRVEAVFALERESALGVVTDALDSPRYRSLLKSLDAYFRTAKPGKDPDLSRLHKKVRKRMRAALPMPHGAERDTAMHDARKAARRARYAAEALGLPDAKPIKALQDVLGEEHDRVVTAAALTDLAAGAHQAGEDAFTYGVLLGLVRCDSRDFDRQVRKAWKAARPSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEJ9</accession>
    <name>C7QEJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786183.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1970"/>
    <dbReference type="EnsemblBacteria" id="ACU70890">
        <property type="protein sequence ID" value="ACU70890"/>
        <property type="gene ID" value="Caci_1970"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1970"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_0_11"/>
    <dbReference type="OMA" id="MEAAKYP"/>
    <dbReference type="OrthoDB" id="922937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="48"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="33386" checksum="6006F0B32BA4F25B" modified="2009-10-13" version="1">MASAPHAHSDARDADHAYGTGGTGLGDFLRSRRAAVDPLAAGMPDDGRLRRVPGLRREELAMLAHVSVDYIVRLEQGRTTRVSRTVLDALADALQLAPDERAYLFTVADVTHSAPTRRPSQSEAAPRLHRLLDTMTDIPAIVVNHRMDVLAWNRGAAGLLTDFSALPPAHRNMIRLTFLDESFRTLYADWPRAGKNCVATLRMEAGSRPNDPALNALVGELSVRDQNFRTWWATHQVRGPSELVKTYNHPLVGTMHLDVQQFSVDTHPDQKLIAFTAEPGSESEKALQFLLQWSDAHATADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEP3</accession>
    <name>C7QEP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72813">
        <property type="protein sequence ID" value="ACU72813"/>
        <property type="gene ID" value="Caci_3927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3927"/>
    <dbReference type="HOGENOM" id="CLU_1892408_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14927" checksum="3A151DB925115391" modified="2009-10-13" version="1">MQGRGGRRIPPPQPFNSRARELRDYMQELRKESGWTIAAIAQHGGGSPVTLAAALRGPRLPSWRTIELFLLGLDVNEDDVHFNKYDGEPSWADSDFLLAQSDVVLRLRGLWLAARAAARGEADQTSTRTDSQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF18</accession>
    <name>C7QF18_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794505.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5918"/>
    <dbReference type="EnsemblBacteria" id="ACU74776">
        <property type="protein sequence ID" value="ACU74776"/>
        <property type="gene ID" value="Caci_5918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5918"/>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153062_1_0_11"/>
    <dbReference type="OMA" id="RPNQRAC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="95" mass="9915" checksum="B3086E9A8D56BBBC" modified="2009-10-13" version="1">MSVDFSFDGRPLTAQPGQTVGAALLAEGIRSWRTTRFSGRPRGLFCGIGVCFDCLVTVNGEPNVRACLAVVAEGDVVRTQVGDGRGGERGGEGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFB1</accession>
    <name>C7QFB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796413.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7865"/>
    <dbReference type="EnsemblBacteria" id="ACU76688">
        <property type="protein sequence ID" value="ACU76688"/>
        <property type="gene ID" value="Caci_7865"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7865"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OMA" id="DRFDFMW"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="21527" checksum="7133650DE049591C" modified="2009-10-13" version="1">MNYSPYGEAPDPQPAVGPTTSVKIVVAGGFGVGKTTFVGAVSEIAPLTTEAVMTAASEGVDDLTVVPGKVTTTVAMDFGRVSLDRELILYLFGTPGQNRFWFMWDDLCRGAIGAVVLVDTRRLADCFSAIDYFEDAGLPYIVGVNCFDGMLTHEVADVREALSIPPDVPVVTCDARSRESTKLTLIRLVEHAMSRFAAAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD3</accession>
    <name>C7QFD3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796435.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7887"/>
    <dbReference type="EnsemblBacteria" id="ACU76710">
        <property type="protein sequence ID" value="ACU76710"/>
        <property type="gene ID" value="Caci_7887"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7887"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_11_2_11"/>
    <dbReference type="OMA" id="QKGLAWM"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="196"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="48321" checksum="9CEEE8F38E77A69F" modified="2009-10-13" version="1">MTSTPDSEEVPYGEVVGFLRDLIRIDTSNPVKPERPAAEYVAEKLAEAGLEPQIFESEPGRASVVARVEGSDPSADALLLHGHLDVVPADPADWTADPFGAEVRDGMVWGRGAVDMKDMDAMMLAVTRRMLREGRKPRRDIVLAFLADEEAGGNYGAKFLAKEHPDLFDGVSEAVSEVGGYSYEVSPDLRFYLIETAQKGLAWMRLQARGQAGHGSMINDDNAVTAVAEAVARIGRHDWPVTLTPTVTTFLSEVTEALGVDFDPKDPASARAAVAKIGPLARFIGATLQHTANPTKLEAGYKVNVIPERAFAEIDGRFLPGLEQEYFAEIDKLLGPDITREFTHYDIALEAPFEVPLVEKMLVSLQAEDPAARIVPYCLSAGTDNKTFGVMDMGRGVIRGYGFVPLKLDPSLDFAAMFHGVDERVPLDALEFGSKVLDRFLTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFF8</accession>
    <name>C7QFF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796460.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7912"/>
    <dbReference type="EnsemblBacteria" id="ACU76735">
        <property type="protein sequence ID" value="ACU76735"/>
        <property type="gene ID" value="Caci_7912"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7912"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_5_11"/>
    <dbReference type="OMA" id="AYAKQTE"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983099" evidence="1">
        <location>
            <begin position="33"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="49"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="41404" checksum="4F539AF6BAF90EB4" modified="2009-10-13" version="1" precursor="true">MHSTSILRRYSAAAIAAAAIAALAACGSPSKAAGGSSGGGSSSGGSAAPIKVGLVYSETGALADYGKDYYQGFLAGLDYATHGTDAVNGHKIEVTQRDDAGDPTKAVSAAKDLIGQGYHILAGSTASGVALQVAPLAAQNKVLFISGPAATDAVTGLNKYTFRSGRETYQDIATAASFLGDLTYKHVTVLAQDSAFGQANVEAVKAVLGAKGATVDSVLAPPSATDLTPFATQAKNAKPDLLFVAWAGTTASALWTALSQQGVLDSTTTVTGLDVRASYPVFASTGGKVSFLAHYVPGGTSNDAAKAMDAYLAAHSEQSDLFSPDGFTAAQMVVHAAQNGDTDVDAMVKNLEGWSFDGIKGAYTVRASDHALLQPMFQAKLEGTTPTVVKTLDPNEVAPPAKTFPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFP5</accession>
    <name>C7QFP5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0029</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784279.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0029"/>
    <dbReference type="EnsemblBacteria" id="ACU68984">
        <property type="protein sequence ID" value="ACU68984"/>
        <property type="gene ID" value="Caci_0029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0029"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_0_11"/>
    <dbReference type="OMA" id="GIQMWRS"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982828" evidence="6">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU68984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="23397" checksum="9339BF91ADD4E82B" modified="2009-10-13" version="1" precursor="true">MLATLLPFLIACTAVAAVPGQSTALIIRQSIRGGKRAGFATVLGNESGVFVWGCAAAFGFTALLAASEIAYDGMRVVGACVLVWFAVQSFRSARRMKQDEAAEETDELGGDARTKGPLWSYRAGLLTNLANPKAAIFAMSFLPQFVPAHAPKLPTMVLLAATWAVYEVFYYSLYVWCVQRLRAFFSRREVRRRMEQISGTVMLGLAVRMVVENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFY0</accession>
    <name>C7QFY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2037"/>
    <dbReference type="EnsemblBacteria" id="ACU70957">
        <property type="protein sequence ID" value="ACU70957"/>
        <property type="gene ID" value="Caci_2037"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2037"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_8_3_11"/>
    <dbReference type="OMA" id="THEPMEA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="57"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16590" checksum="A6070D7B16F69328" modified="2009-10-13" version="1">MTEPVRLHVIQGGRAEQPTKQPTKQPTNHAPSQPPNQPPKQSATPEPLWREVLGDQLRELRREHRESLAETAGRAGISPQYLSEVERGLKEPSSEMIAAVAGALGTTLGGLAESVAGELRVRREATLVISRREAATRVATRRPASGPVMLALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGE2</accession>
    <name>C7QGE2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4123"/>
    <dbReference type="EnsemblBacteria" id="ACU72987">
        <property type="protein sequence ID" value="ACU72987"/>
        <property type="gene ID" value="Caci_4123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4123"/>
    <dbReference type="HOGENOM" id="CLU_2567565_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="8462" checksum="6B2C1A6C5CDCD619" modified="2009-10-13" version="1">MSGEDDGAELVEVEEDGEGEPEASLGEPEAPGGEPEAPPATRQAALPRRVPSQSPSRTAPAVTQPAEQTVLHLLTILKRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG6</accession>
    <name>C7QGG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73011">
        <property type="protein sequence ID" value="ACU73011"/>
        <property type="gene ID" value="Caci_4147"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4147"/>
    <dbReference type="eggNOG" id="ENOG503307Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1531758_0_0_11"/>
    <dbReference type="OMA" id="WHERNWR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="21453" checksum="9F09451C7612A0E1" modified="2009-10-13" version="1">MITYWNPLPTARRLVDTDDRDPFTGKWAERKPRNVPGPFYSASTDSLQTGRLDAPDHIAYDDDLGGGFGWEFVYRQPVNAAGTEAVVNAARLELYSGYACDGDDHWTVEAVRDWWRERGEIRAWAVDLAVQWEANAHPKYRGHYHDAAHGLREFIAFIDDGLDRYLRGYMFWLAEGCSPEAGRLTPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGH6</accession>
    <name>C7QGH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiamine biosynthesis protein ThiS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5998"/>
    <dbReference type="EnsemblBacteria" id="ACU74856">
        <property type="protein sequence ID" value="ACU74856"/>
        <property type="gene ID" value="Caci_5998"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5998"/>
    <dbReference type="eggNOG" id="COG2104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174611_2_2_11"/>
    <dbReference type="OMA" id="EPHEFAS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472">
        <property type="entry name" value="PTHR34472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="8201" checksum="57A73107A62892A7" modified="2009-10-13" version="1">MSAEQTMQHTMQLSVNGAPSQIAEGATVADLVVSLVEAARDGKKGGIAVAVNETVVPRASWDGTPLAAGDRVEILTAVQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHM7</accession>
    <name>C7QHM7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786345.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2133"/>
    <dbReference type="EnsemblBacteria" id="ACU71052">
        <property type="protein sequence ID" value="ACU71052"/>
        <property type="gene ID" value="Caci_2133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2133"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_3_11"/>
    <dbReference type="OMA" id="MGDRWHV"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="8250" checksum="C50FECD18A0C11FC" modified="2009-10-13" version="1">MAETKWRVTVDTDLCIGSGGCVLRAPDAFELDTARQSCPKHEVMAPSDDVLEAAETCPVEAITIVEEGSGAEVFPPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC3</accession>
    <name>C7QIC3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric reductase domain protein with transmembrane component domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6146</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794729.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6146"/>
    <dbReference type="EnsemblBacteria" id="ACU75000">
        <property type="protein sequence ID" value="ACU75000"/>
        <property type="gene ID" value="Caci_6146"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6146"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_19_1_11"/>
    <dbReference type="OMA" id="CGEFHPF"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000951">
        <property type="entry name" value="Ph_dOase_redase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00409">
        <property type="entry name" value="PHDIOXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="227"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="49670" checksum="A7BF27A88A1BB90C" modified="2009-10-13" version="1">MSTTVLPGDTAPTGVKTSPETVPRLALALMAAGAAAVLTAWWHATASVVGGAGWLDGAGRITGLLAGYLAPVLLLLMARIPVLERRVGSDRLARWHALGGRYMVFLVSAHVVTIIWGYALTDGKNPFAEGVQIVFHYPAMIKGSLGTLLLFGTGIVSARAARRKMRYETWYYLHLATYLAIALAFSHQIINGADLSVQPEQTLWSAYYVLAAVTLGWYRLWMPYLHDRRHKLRVHTVVPEGPGVYSVILKGERLDELKVRPGQFFRLQFQTRDLRWVANPYSLSAAPHPNYLRFTIKSLGDHSAAVSSLRPGTKVRAEGPYGAFTEDKARSPQVLLIAAGVGITPVRALFETLPGRLTLLYRAGSDREILFRHELEDIARERGARLVYLVGSRRRHGKTFTPRGLLNLVPDLKAHDVYLCGPEAMQQAVIVALRDAGVPASRIHHESFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ7</accession>
    <name>C7QIQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796682.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8134"/>
    <dbReference type="EnsemblBacteria" id="ACU76957">
        <property type="protein sequence ID" value="ACU76957"/>
        <property type="gene ID" value="Caci_8134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8134"/>
    <dbReference type="HOGENOM" id="CLU_2552082_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="9074" checksum="0DC642D004DCF143" modified="2009-10-13" version="1">MTPPRRVGVPPLNLGNQAVADRLDRHFAAMVDAPPAAHDDNNAQEALQTMIAVLPRTGGARRSERALWLRAPFRRLKRLIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIT7</accession>
    <name>C7QIT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796712.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8164"/>
    <dbReference type="EnsemblBacteria" id="ACU76987">
        <property type="protein sequence ID" value="ACU76987"/>
        <property type="gene ID" value="Caci_8164"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8164"/>
    <dbReference type="eggNOG" id="ENOG50339I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435960_0_0_11"/>
    <dbReference type="OrthoDB" id="2142576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="641" mass="69307" checksum="BFC541F80D25B2D1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIW4</accession>
    <name>C7QIW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8191"/>
    <dbReference type="EnsemblBacteria" id="ACU77014">
        <property type="protein sequence ID" value="ACU77014"/>
        <property type="gene ID" value="Caci_8191"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8191"/>
    <dbReference type="eggNOG" id="COG3247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091585_4_0_11"/>
    <dbReference type="OMA" id="GIGWLFR"/>
    <dbReference type="OrthoDB" id="1918376at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005325">
        <property type="entry name" value="DUF308_memb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03729">
        <property type="entry name" value="DUF308"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22245" checksum="0A723372483DC448" modified="2009-10-13" version="1">MTDMYDGDARGPDRGDVDYPLRMLGQAAWQALMVLGLAAIAIGVCVVVWPDRTLLVLGVLFGIYLLISGVMEIIAAFGEHVSAGMRVLNVIVGALSILLGLFCFRNSLHNSVLLLSLWIGIGFLMWGIATIATAASAPSGVVGRGWAFFAGFVTMLGGIIVISWPIGSIVTLAVFTGIWLIAVGLIEVIHAFTLRSKVKHVAGGAGRHATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ67</accession>
    <name>C7QJ67_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784504.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0256"/>
    <dbReference type="EnsemblBacteria" id="ACU69209">
        <property type="protein sequence ID" value="ACU69209"/>
        <property type="gene ID" value="Caci_0256"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0256"/>
    <dbReference type="HOGENOM" id="CLU_2045464_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="12286" checksum="BFF7B6252F27B87B" modified="2009-10-13" version="1">MVVDGGAEGVGDASSVGGGELSVVEAVVEPEADADFEVDVEAAPLLVLLLVLVLVAGFAGDADELLLPHAPRAALSAIAHPAATTVRILTVSGIEFPVLHWSQDGWWTFHLARGLPARAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJT8</accession>
    <name>C7QJT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4312"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73176">
        <property type="protein sequence ID" value="ACU73176"/>
        <property type="gene ID" value="Caci_4312"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4312"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014141_0_0_11"/>
    <dbReference type="OMA" id="VWKVYVY"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981049" evidence="3">
        <location>
            <begin position="40"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="5">
        <location>
            <begin position="174"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="4">
        <location>
            <begin position="870"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1007" mass="105994" checksum="B9E392B2F98760E9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU9</accession>
    <name>C7QJU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792916.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4323"/>
    <dbReference type="ESTHER" id="catad-c7qju9">
        <property type="family name" value="HNLyase_Bact"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73187">
        <property type="protein sequence ID" value="ACU73187"/>
        <property type="gene ID" value="Caci_4323"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4323"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_3_2_11"/>
    <dbReference type="OMA" id="PWRRFDL"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="248" mass="26737" checksum="9B966C6BE7D958A5" modified="2009-10-13" version="1">MATFVLVPGLWLGSWVWDAVAGRLRADGHTVHALTMPGIAERAAEAKPDTDLRTEIADIVAYLREHGLREVVLVGHSGANMPVTGVIDEVPELITRVVYVDSGPMPSGLGVIDFLPPQAQDAQRRQVAEQGEGWLLPPPPFDAEQDPVNLAGISEAELERVRGLASPQPFRTTTDALDRPGDPMPVPASAITCTFTPEQVAQLAETGNPIFALMTKLELHPLPTGHWPMLSRPDDLAVLLGQVGQVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW7</accession>
    <name>C7QJW7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4341</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792934.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4341"/>
    <dbReference type="EnsemblBacteria" id="ACU73205">
        <property type="protein sequence ID" value="ACU73205"/>
        <property type="gene ID" value="Caci_4341"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4341"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="RARQNWD"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="23802" checksum="6D4BA658ACA9E7CD" modified="2009-10-13" version="1">MPEALFSPTGSSPGALPSRTEAVLEAIKHAILTGELKPGQALVETDLAGELGVSKTPVREALKTLAGTGLVTMSPYKGATVREIDRAHARSIYDMRLLLEPTAAGRSVGVHRDWAPARAALEAADESTDAAGRSLANRAFHRHMYLACGNPLLVRTLDDLRDQTALVSAAAWAQRPSWEREAAEHRAILAAAENGDTEEVRDLMRSHISSFVARTFPEDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE7</accession>
    <name>C7QKE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796771.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8223"/>
    <dbReference type="EnsemblBacteria" id="ACU77046">
        <property type="protein sequence ID" value="ACU77046"/>
        <property type="gene ID" value="Caci_8223"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8223"/>
    <dbReference type="eggNOG" id="ENOG5031R9K">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111492_0_0_11"/>
    <dbReference type="OMA" id="IRKEYAW"/>
    <dbReference type="OrthoDB" id="1812124at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19946" checksum="AEEB823D92BBA4CF" modified="2009-10-13" version="1">MGGDRESLKAAARTAVLEAVADAGVEYERPEEGTFVVKLPGEHKLWTTCSLVVGDHTLSLNAFVARRPDENHEGVYRWLLERNTRLGSLAFALDKLGDVYLVGRLPLGLITAGTVDQLLGEAVAASDSSFDQLLELGFASAIRREWEWRTSRGESLANLAAFRHLIERTPGTRDENGTEAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKI9</accession>
    <name>C7QKI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8265"/>
    <dbReference type="EnsemblBacteria" id="ACU77088">
        <property type="protein sequence ID" value="ACU77088"/>
        <property type="gene ID" value="Caci_8265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8265"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="YWPRILT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="245"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="35846" checksum="C9AA80A2BE542172" modified="2009-10-13" version="1">MAASLSFTAEELAQVRFSVSPMWEVLTSFRVLTRPGLYPVHGPWFDQVRPRLAAAGLLTGHLSALFHAPSYVPDFLTPAPANSTPTLEEELAAIQATSEDHLSADLDIYDEKVPNGVIPPFAERLRNHREQALGELSKDIEHYFQIALAPYWSRIKTLLESDIYYRARQVAEYGAARLFNDLHPDVSWNSGTLRMLHRQRVLCRDDNAPGLILVPSAFAWNKIYTRAATGDVPQLCFGARGVGTLFERRAAGPSDAVAAVIGRSRALLLAELEAPASTSDLATRTGMSAGGVSEHLTALRGAGMVSAHRAGRSVLYARTSVADSLLAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ9</accession>
    <name>C7QKQ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8335"/>
    <dbReference type="EnsemblBacteria" id="ACU77158">
        <property type="protein sequence ID" value="ACU77158"/>
        <property type="gene ID" value="Caci_8335"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8335"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_0_11"/>
    <dbReference type="OMA" id="GERTCFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="22838" checksum="28EC697A6CAABD86" modified="2009-10-13" version="1">MAAEEIRARTVYQVFRTGDSLTGEGEDTHRVFFIQSGWVSVIQHSTVGATRILAVRGPGDVVGELASLSERPRSATVRARSTVEARGMSGEAFIDLAERTPSIARALFRILADRLHDADRHRTQLHGSVALGAVADKLLEIHSYADSGQDRPVFTQEEIACWAGVSVPALARSLRTLREAGVIRSARQRILVLDEKSLREVAQNGRVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVG4</accession>
    <name>C7PVG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative GAF sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784615.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0367"/>
    <dbReference type="EnsemblBacteria" id="ACU69320">
        <property type="protein sequence ID" value="ACU69320"/>
        <property type="gene ID" value="Caci_0367"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0367"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_801456_0_0_11"/>
    <dbReference type="OMA" id="NDERQMF"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="37"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="33295" checksum="DFC01F82D6EF4745" modified="2009-10-13" version="1">MTDRDDFQTPALRLGQPAPSDAAARAARQRELSLSATADSVFDEVARRAAEATGATAAMVNMVGENGQYLVGLYGKEPGSGEAAFLGDPGRYAAMDQGFCVHVVGRKAALTLDDVFDFSRFRGNPIVDELGVRSYIGVPLIDDGGTVIGTVCAIDPAPRSESDGNSWGNQGLQVLKAARDEVLAEISGRQKIAAILENAGGTAMIAARPGLEVLYANTLHDQLFGAVQVLGTPALEAFPHLAPVGILAVIETLDRGGEPTTTAPIPLSEPATGSVIFAAVPVRVPGHASAVLTLGLRDSDAATVLNRAAQIAADIGALSDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVK6</accession>
    <name>C7PVK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69362">
        <property type="protein sequence ID" value="ACU69362"/>
        <property type="gene ID" value="Caci_0410"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0410"/>
    <dbReference type="eggNOG" id="ENOG50339I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435960_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="632" mass="68586" checksum="6D0751724FDE7F9D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVL0</accession>
    <name>C7PVL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784661.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0414"/>
    <dbReference type="EnsemblBacteria" id="ACU69366">
        <property type="protein sequence ID" value="ACU69366"/>
        <property type="gene ID" value="Caci_0414"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0414"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_5_0_11"/>
    <dbReference type="OMA" id="QYLKYPG"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="25356" checksum="CDDFE16D1ED3BE84" modified="2009-10-13" version="1">MAAEPAEPAEPAEPAPRKTPITLERITDAALQVVATEGYDALTIRRVTNVLGTGPSSLYAHIATKTDIDDLLIGRLCSEITLPDPDPATWQHQLRDVYAQLRDQYLKYPGISKAALATVSANPETLRVSEGIFAILLSAGIDPQTAAWTMDAITLYVAAYALELSLVHHRRKDPTTPWLLSHEALTAHLTSLPEATFPQTRRHAAALTSGTGHQRFDFALTLLIDNLTSQTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW72</accession>
    <name>C7PW72_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793049.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4457"/>
    <dbReference type="EnsemblBacteria" id="ACU73320">
        <property type="protein sequence ID" value="ACU73320"/>
        <property type="gene ID" value="Caci_4457"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4457"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="CHNLETA"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="23"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26955" checksum="0D79100E6B344239" modified="2009-10-13" version="1" precursor="true">MTAPHAVSATSATDPSGHGGAAVTLERVTKTYGRVTALDNVSWAFRRGSFTAIMGASGSGKSTFLHCASGLDRPTSGTIRLGETDLGKLKETALTELRRDRVGFVFQGYNLVPSMDVQRNITLPLTLGGRRADSGWLTEIVHRVGMADRLGTKPSQLSGGQQQRVAVARALVTRPEIVFADEPTAALDPRTAGHVLRLLREAADATGQTVVLVTHDPTAAAWADSVVFLSEGRIVDELARPTAATVLNRWETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWF7</accession>
    <name>C7PWF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794966.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6383"/>
    <dbReference type="EnsemblBacteria" id="ACU75237">
        <property type="protein sequence ID" value="ACU75237"/>
        <property type="gene ID" value="Caci_6383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6383"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_1_0_11"/>
    <dbReference type="OMA" id="CEEKLGL"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="24"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="20387" checksum="F04A79450A0E276F" modified="2009-10-13" version="1">MSHIELGVDETLFPGISGPMLFRPQTAAPMSDLVEVLLRGENTLSRGERELIAAYVSSKNDCEFCTDSHSAFAAAQLDEGMPLVLRVRADPDEAPITPKLAALLRIAGAVAKSGREVTTELVGTARAQGATDEEIHDTVLIAAAFCMYNRYVDGLGTLPAGRAEDYQAAAEAVVANGYLPLAGRAPSALNVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK8</accession>
    <name>C7PWK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795017.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6436"/>
    <dbReference type="EnsemblBacteria" id="ACU75288">
        <property type="protein sequence ID" value="ACU75288"/>
        <property type="gene ID" value="Caci_6436"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6436"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_8_4_11"/>
    <dbReference type="OMA" id="CSVEAWR"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16841" checksum="C1D142622F717E8B" modified="2009-10-13" version="1">MTAAEPQRDLVHLLSMAEHRAVRRQSALLEAEAEGCSIEQWRVLNLLADGLGHTMTEVAEYALLPAPTATKLIDRLVTDNLVYRHPDPADRRRVLVHAAQRGRELHARLAPSLARMQSEVLRPIGTGEELEALLDHLARVLDPGSARAGQVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWR0</accession>
    <name>C7PWR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795069.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6490"/>
    <dbReference type="EnsemblBacteria" id="ACU75340">
        <property type="protein sequence ID" value="ACU75340"/>
        <property type="gene ID" value="Caci_6490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6490"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2132055_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11997" checksum="9926669514F18975" modified="2009-10-13" version="1">MTNGEDDFVATVVIPVADADKARELIEAMAEDVRQWVRHLPGFVSANYHISLDGKRVFNYARWTNEKAYLDGFRADPRSAAMREQILALAEGGPEMVGYQPVRSVVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX56</accession>
    <name>C7PX56_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter, periplasmic phosphate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0455</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0455"/>
    <dbReference type="EnsemblBacteria" id="ACU69407">
        <property type="protein sequence ID" value="ACU69407"/>
        <property type="gene ID" value="Caci_0455"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0455"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034528_3_0_11"/>
    <dbReference type="OMA" id="AISEIPY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980423" evidence="3">
        <location>
            <begin position="39"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="4">
        <location>
            <begin position="35"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="57689" checksum="71676286F7FBCEB7" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA4</accession>
    <name>C7PXA4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784750.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0509"/>
    <dbReference type="EnsemblBacteria" id="ACU69455">
        <property type="protein sequence ID" value="ACU69455"/>
        <property type="gene ID" value="Caci_0509"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0509"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029337_0_0_11"/>
    <dbReference type="OMA" id="HEPDWAL"/>
    <dbReference type="OrthoDB" id="1149824at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003032">
        <property type="entry name" value="Ryanodine_rcpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02026">
        <property type="entry name" value="RyR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="3">
        <location>
            <begin position="119"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="607" mass="66589" checksum="DFD3D9718C1C26AC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF8</accession>
    <name>C7PXF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2493"/>
    <dbReference type="EnsemblBacteria" id="ACU71411">
        <property type="protein sequence ID" value="ACU71411"/>
        <property type="gene ID" value="Caci_2493"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2493"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="HFDWHDE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="30630" checksum="1D1E99E249543F00" modified="2009-10-13" version="1">MAILVIGATGKTGRPVVDALAARGAKVAAASRNPEAGRELPDGVTPVRFDWADRTTWTSALEGAEALYIVGPYAHPTGERLVADLLAEAHDTHRVVLLSVIGAELLPVEAMMAHWERAVRASGKEWTILHPNWFFQNFGTGFLPSLRDRGVLQLPAGDAPVSFVDTRDIGEVAAAALTEDGYAGQVLTITGPDSLSHGEAVAMLSEASGRPLAYKPVEPEQAEANSRAAGVSERTIIAQRGLFQVIRDGGNAPVTDVVQRVTGHAPRSFAQYAAEHADLWRDATNSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXW6</accession>
    <name>C7PXW6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793155.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4564"/>
    <dbReference type="EnsemblBacteria" id="ACU73426">
        <property type="protein sequence ID" value="ACU73426"/>
        <property type="gene ID" value="Caci_4564"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4564"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_11"/>
    <dbReference type="OMA" id="YAYAKTT"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="33990" checksum="E7B5F2F63EB2C1EF" modified="2009-10-13" version="1">MSNPTNPVLVTGGSGYLGTHVVAALLREGRPVRATVRSLSREAGLREAVRRGGADDAGLEVVAADLMADDGWKAAVAGVEEVHHVASPIPVAQPADPDELIVPAREGTLRVLGAARDAGARRVVLTSSFAAIGYTPKPDADYTEADWTDPDTPGLAPYPRSKAIAERAAWDLMAGAATELVVVNPTAIFGPTLSPVLGASMALIKAMLDGTMSVAPRARFGVADVRDVADLHLRAMAAPQAAGKRFLALTDGPALSFVEVAAILRDRLGDLAALAPTAEADGPEPPRPVIHNDRAREELGWRPRPAEATIVESAESLRDLGLLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY07</accession>
    <name>C7PY07_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="5">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4606</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4606"/>
    <dbReference type="EnsemblBacteria" id="ACU73467">
        <property type="protein sequence ID" value="ACU73467"/>
        <property type="gene ID" value="Caci_4606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4606"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026434_6_2_11"/>
    <dbReference type="OMA" id="MHAAERY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020803">
        <property type="entry name" value="PKS_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00828">
        <property type="entry name" value="PKS_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_MT" evidence="4">
        <location>
            <begin position="159"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="47198" checksum="866B137504AC009C" modified="2009-10-13" version="1">MQDSCMGTNTTVAAVFRPLLTAALGTAPPPVRFEFWDGSSLAPRTGRTVGAVVVRSKDALAHMVWAPGELGLVRAFVAGDLDFSGDIFTVLRTLQQGAPNDASLGAQAALKALGAAAKMGALRGRPAPPEQEAHPKGRLHSKRRDSQAISHHYDVGNEFYELVLGESMTYSCARFVSPEDDGSQGPAATMALADAQAAKHDLICRKLGLDRGPGMRLLDVGCGWGSMAIHAATHYGARVVGITISAAQAELARERVAAAGVSDQVEIRLQDYRDLSGERFDAISSVGMFEHVGTERTAEYFDTLFALLGPGGRLLNHAISSPGGSKISSRSFIGRYVFPDGELLDAGVTAAAMQQAGFELRDVEALREHYALTLRAWVENLQKNWDRAVELVGVGRARVWLLYMAGSALGFEDGGIGIHQLLGVVPEESGAARMPASRRSWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY49</accession>
    <name>C7PY49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793238.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4648"/>
    <dbReference type="EnsemblBacteria" id="ACU73509">
        <property type="protein sequence ID" value="ACU73509"/>
        <property type="gene ID" value="Caci_4648"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4648"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_3_0_11"/>
    <dbReference type="OMA" id="RFRPQQW"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="27"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="31075" checksum="286F59CC70A14B6E" modified="2009-10-13" version="1">MKIHHLNCGSVREIERTYEGPAAAHAVNHCLLLETDGDGLVLVETGLGLVDIADPDGVLGAGWVKASQPVLAEQETAIRQVEGLGFGAGDVRHIFLSHLDVDHCGGLPDFPEAQVHLLRAELEAALAQAPSARYRPAHWEHGPKWVQYAPEANDQWFGFSAQQAEGLSEEILMVPLGGHTEGHTGIAVRDGDDWLLHCGDAYYYHRELDDEPEPHPLLNWVQTTYETHHDLRLGTQARLRELVRAHGDQVTLIAAHDPWEFARLQQLQQPRGSERRVAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYF5</accession>
    <name>C7PYF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795174.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6599"/>
    <dbReference type="EnsemblBacteria" id="ACU75445">
        <property type="protein sequence ID" value="ACU75445"/>
        <property type="gene ID" value="Caci_6599"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6599"/>
    <dbReference type="eggNOG" id="ENOG5032Z2S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126480_0_0_11"/>
    <dbReference type="OMA" id="LAMFEFF"/>
    <dbReference type="OrthoDB" id="1764449at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="8">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="7">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14967" checksum="F93BE72D40349113" modified="2009-10-13" version="1">MSHPLLNAFWMIFWFFLWIMWFMLLWRIISDVFGDHDLSGWAKTGWIIFVCVLPFLGVFIYLIVRGKSMTARQIQRAQANQQQFDDYVRQTASTTPSNSAEELSKLATLKADGVLSEAEFQQAKQKILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYJ2</accession>
    <name>C7PYJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797039.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8491"/>
    <dbReference type="EnsemblBacteria" id="ACU77314">
        <property type="protein sequence ID" value="ACU77314"/>
        <property type="gene ID" value="Caci_8491"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8491"/>
    <dbReference type="eggNOG" id="COG3307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045372_0_0_11"/>
    <dbReference type="OMA" id="HPIEFGV"/>
    <dbReference type="OrthoDB" id="1369131at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="469" mass="50076" checksum="F7B6D96786560A31" modified="2009-10-13" version="1">MSAPAPPRLRRSTAGHSNALAVTRHHDLVHPDAKPSRWDAASVLTVYATLVMLAPATQTVANLGALGAPATVFSVLAFMWFLAGRLTGRLSLDPGSSSVRKAMCVLATAFTLSYICLSGRSASPLETQAADRALILMLIWCGLVVVASAGITKRDRLETLLRRLVLLGTVVAVIGIFEFFSGWQLTEHVIIPGLATNVDPAATGARGGHLRAQATTTQPLEFGAVIAVHLPFALQQAGDAKRWGTGLRNKLRRYGPVTVMVISLPMTVSRTAIIGLVVVLAVLMPSWPKQRRRPAYLMTVVGAAAVRVLVPGLLGTILVLFSSASGNSDNSSQARTKDYAGVTPYIKQRLWFGRGPSTFIPSLYRYTDNYYLLALVEVGLVGLLAVLVIYFTGIRAGRLGRKLSVDEPYRDLGQCFAATFAVMLFISATFDTLSFPMLSGLLFLLFGCSGAYLGIARSEAAARAQAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYK0</accession>
    <name>C7PYK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine--scyllo-inositol transaminase</fullName>
            <ecNumber evidence="4">2.6.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.50" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8499"/>
    <dbReference type="EnsemblBacteria" id="ACU77322">
        <property type="protein sequence ID" value="ACU77322"/>
        <property type="gene ID" value="Caci_8499"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8499"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_2_11"/>
    <dbReference type="OMA" id="QVHYKPI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047310">
        <property type="term" value="F:glutamine-scyllo-inositol transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080100">
        <property type="term" value="F:L-glutamine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="40575" checksum="2BD9B74E38046DAE" modified="2009-10-13" version="1">MTSAVATEAEAAPRIPVMVPWLGEEEAEAAAEAVRSGWVAQGPRVAEFERAFAAEVGAAHGVAVSSGTTALHLGLVALGVGAGEEVVVPSLSFIATANVARYVNAVPVFADVDVATGNLTPETITAALTPKTRAVILVHQGGVPADLDAVRALCADRGLALLEDAACAAGVRYRGAPVGVGAQVAAWSFHPRKLLTTGEGGMATTDDADVAARMRRLREHGMNVSAADRHASTKPVLEAYLETGFNYRMTDIQAAVGLVQLRKLAATVAERREIAARYQRELAGIAGLTPVADPAYGQTNYQSFWVRLDEGFPVSRDELLLRLSDAGVSARRGIMAAHMEPAYADVSTPRLPNTEALSLNSLILPVFHGMTASQQDRVIAVLKAASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL1</accession>
    <name>C7PYL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8510"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77333">
        <property type="protein sequence ID" value="ACU77333"/>
        <property type="gene ID" value="Caci_8510"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8510"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084695_0_0_11"/>
    <dbReference type="OMA" id="RDYYRIW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="31213" checksum="143BF60058C013F2" modified="2009-10-13" version="1">MRYWAIVVSVIIPAHNEASVVGRLLSRLLADAAPGEFEVWVVANGCTDDTAEIAGAFADVKVLIAPEANKHAAMRLADEHAEGFPRLYVDADVEFGARDVRALAAAFDDPGVLAAGPSRALPPERRPWTVRWFYDVWDQLPVVRAGLFGRGVVGVSREGWERLRALPPLLGDDLAASLLFEPAQRRVVSESTVIVHPPRTAGALLRIRTRALVSTLQAADDSELSSASDSARTSLSDLRAIALASPVRATPKVAWFLVLTVATKIRARRAVRAKDFRTWHRDDTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX9</accession>
    <name>C7PYX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WGR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784830.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0598"/>
    <dbReference type="EnsemblBacteria" id="ACU69535">
        <property type="protein sequence ID" value="ACU69535"/>
        <property type="gene ID" value="Caci_0598"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0598"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006807_1_1_11"/>
    <dbReference type="OrthoDB" id="214704at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4132" evidence="1">
        <location>
            <begin position="844"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1125" mass="124222" checksum="0192A3E3EDDB2017" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ02</accession>
    <name>C7PZ02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0622"/>
    <dbReference type="EnsemblBacteria" id="ACU69558">
        <property type="protein sequence ID" value="ACU69558"/>
        <property type="gene ID" value="Caci_0622"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0622"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_4_1_11"/>
    <dbReference type="OMA" id="RMAPNTS"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20413" checksum="CEA1A67D445B5B7C" modified="2009-10-13" version="1">MRGRITSGNPGRYRFAHLGPGAALSFPLGALYNEQYMAIGEGTLVGEGVSLAVGWPDEDFGEEIVLRIGRGCSIGRGSHIVAHLRVDIGDDVFFGPYVYVTDQNHGYVALDTPIGRQDAEDKPVTIGDGCWLGVGSVILPGTTLGRNVAVAAGAVVRGSFPDHCLIGGVPARILRRHHDEDGWRADLQAPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ30</accession>
    <name>C7PZ30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0650"/>
    <dbReference type="EnsemblBacteria" id="ACU69586">
        <property type="protein sequence ID" value="ACU69586"/>
        <property type="gene ID" value="Caci_0650"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0650"/>
    <dbReference type="eggNOG" id="COG3154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070584_1_0_11"/>
    <dbReference type="OMA" id="HETSIHR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010872">
        <property type="entry name" value="MDMPI_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07398">
        <property type="entry name" value="MDMPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="MDMPI_C" evidence="1">
        <location>
            <begin position="146"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="27715" checksum="5A205766C9F44A79" modified="2009-10-13" version="1">MDRIAHFERETTAFHRAALMAAVPDTPLPVPSCPDWTTADLVRHLGRVQRLVNHVIVERLETMPPDRKTMFRAPTDATADDLADWFAEGATALAETFRSTDPKTAVWTWGDVHGVSFWLRMQTIEAAVHRWDLEGAIGSPQPVDKELAGDGVAQFLDDVIPFRRRTKSVPPMEGERYRFRQTDGSGVWSVALEPDGLRPLGEDEPADAELAGTASDLLLFLWHRIPGEPLLVSGDAKALQRFFVLVPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ67</accession>
    <name>C7PZ67_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784918.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0688"/>
    <dbReference type="EnsemblBacteria" id="ACU69623">
        <property type="protein sequence ID" value="ACU69623"/>
        <property type="gene ID" value="Caci_0688"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0688"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070317_0_0_11"/>
    <dbReference type="OMA" id="KPHFDIH"/>
    <dbReference type="OrthoDB" id="1708552at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11669">
        <property type="entry name" value="TTHB210-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033786">
        <property type="entry name" value="TTHB210-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982347" evidence="1">
        <location>
            <begin position="31"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="30606" checksum="4D3144C297481C61" modified="2009-10-13" version="1" precursor="true">MRSTLRHAVLALTAASIAALGALSVPAASAAARASHTEYGPPVRLGAGTARTYLVSEGSTPLEIGVVVDAAATESLPASPPTDGHHCYDVNGDGRINPVTECAGGYYLPLHLPSDAPAPYRWVLLNWNPSGHGPVGMYDTPHFDMHFYVVPRSAVDAIGYGTCGQLVACDQVPEVAAPLPAKYVPSGYPPALKQTVEVAMGDHLDNDAGFKNGATFVYGSLDGRIAFLEPMIQRDALRQTPAGGPRQCQPVAQPAAWQRSGWYPTSYCLGQTADGGYQVSLDGLVRRHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q041</accession>
    <name>C7Q041_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6688"/>
    <dbReference type="EnsemblBacteria" id="ACU75534">
        <property type="protein sequence ID" value="ACU75534"/>
        <property type="gene ID" value="Caci_6688"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6688"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_2_11"/>
    <dbReference type="OMA" id="FFIRHQQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="3">
        <location>
            <begin position="51"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="40679" checksum="68144DE143953773" modified="2009-10-13" version="1">MDGLWHCQDMPAPTSPAGPARATGSADRAVPNPARQGSIRNANLALLYGLILDAPAPLSRAALAATTGVTRATASALADTLLEAGLVAEVSPPPATGAGRPAAGLVPAAEGPAGLGLEINVDYLAACVVDLTGAVRATVISAGDQRDRSVSEVLADLAGLARQAVSEAGLTVAGAAVAVPGLVEAPHGRIRSAPNLVWQDVEIGAALRSALPETPFEPVVGNEADFAALAEAHGVFDGDADGPAAPLTDFLYVSGEIGVGAGVILDRELFRGARGWAGEIGHVTVQPEGVQCRCGARGCLETVAGLEALRRDGPEAAASALGRAAAAAVNLLDLPAVVLGGAYARPEFAALVPGVEKALADHVISARWAPVAVHVSRRGTAAAVTGAATAVIRRVHADPAAWMAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0D5</accession>
    <name>C7Q0D5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8652"/>
    <dbReference type="EnsemblBacteria" id="ACU77468">
        <property type="protein sequence ID" value="ACU77468"/>
        <property type="gene ID" value="Caci_8652"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8652"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055936_1_0_11"/>
    <dbReference type="OMA" id="TWYVNFA"/>
    <dbReference type="OrthoDB" id="1506401at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980506" evidence="2">
        <location>
            <begin position="28"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="31418" checksum="E8C7F86A956CCBCA" modified="2009-10-13" version="1" precursor="true">MKKSVAVVIASGLLLAGCSSSKSSPKAASGSTTPASTSAANSSSASASASASTSAISAPGPVKVAYAASLANLMEHDVSPAYDKATTGDFQGNAAGSTQLVSEIKGKVKQADVFISASTDANTGLIGDANGGWETWYATFATAPLVIAYNANSKFAADLKSKPWNQVITEAGFKMGSTDPKLDPKGKLAAQALTKDNLPASAVQVFPEEQLVGRLQSGQLDAGFFYSSEAAELNIPTVPLGDIHLQATYTVSVLNKAPDADAGVAFVQYLFSDAGKALMTKHGLQLQPIKVTGDAGSVPAQLKSVLNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0T8</accession>
    <name>C7Q0T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
            <ecNumber evidence="3">3.5.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785011.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0781"/>
    <dbReference type="EnsemblBacteria" id="ACU69716">
        <property type="protein sequence ID" value="ACU69716"/>
        <property type="gene ID" value="Caci_0781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0781"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_0_1_11"/>
    <dbReference type="OMA" id="RAHACGH"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004046">
        <property type="term" value="F:aminoacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="217"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="43487" checksum="3F6EC774EE2BD279" modified="2009-10-13" version="1">MDLAHEAPVASDSAPAPAPDSSGQHPHVLDVAGHLVPELVLFRRDLHANPELSRAEFRTTAAIAARLERAGLAPRVRGVGTGLVCDIVPAGAEKLPFLAFRADIDALPVEESNELDFRSRVPGVMHACGHDVHTAVVLGAGLTLVEMARAGMLARPVRLIFQPAEEVMPGGALDMVAEGALYGVSKILSVHCDPKLDAGQVGLRTGALTAACDLVALTLDGPGGHTSRPHLTADLVYALASIVAEVPAALSRRIDPRAGLSLVWGQISAGSAPNAIPGTGSARGTIRTLDQDAWNQAPDIVHELIDAIAAKFGVKHTLDYVQGVPPVVNEAESVALLRTAATRALGAEAVVSTPQSLGGEDFAWYLQRVPGAMARLGVRTPGDKAVRDLHQGTFVADEGAIAAGIRMLATAALCDWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q261</accession>
    <name>C7Q261_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_8783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797322.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8783"/>
    <dbReference type="EnsemblBacteria" id="ACU77598">
        <property type="protein sequence ID" value="ACU77598"/>
        <property type="gene ID" value="Caci_8783"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8783"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053828_0_0_11"/>
    <dbReference type="OMA" id="WCAACDW"/>
    <dbReference type="OrthoDB" id="1767187at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="125"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU77598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="44112" checksum="B7ECADE1A2C9682E" modified="2009-10-13" version="1">MADDHDLMAKDEHQKLAAQKRFARRKREKARRRGEALEQRLIQAGDLRPGGVARLAAVCFGLAIHALTLLVFAGAMAALLSGIWPLYLLTILGFGVVWVLRPRLEKRPGADWLRREKAPGLFAILDRISGATGAPTPKYVKVDARFNAATARRGVRHEPVLILGAPLWQILDGDERLALLGHELGHQVNGDTTQGVLVATARRSLHEWRVLLYPSGVGWSGPGVAGLAQLLLPVVLVPFYLMVTGFQTFYGWLQVHVSLRAEFLADDIAAQTASTASVIALMRKLDARPSVEAYVTRTKFGRRTARVTPSLEDATHMWIGLQDYITTIPEHEYIRAARLSELRGTQIDASHPANYLRLRLLKGRPTRGAAVKVTEDEWLGVDRELAPYVTEVGRSMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Z5</accession>
    <name>C7Q2Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787180.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2978"/>
    <dbReference type="EnsemblBacteria" id="ACU71887">
        <property type="protein sequence ID" value="ACU71887"/>
        <property type="gene ID" value="Caci_2978"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2978"/>
    <dbReference type="HOGENOM" id="CLU_2932783_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6967" checksum="41FA5CA6F37B486A" modified="2009-10-13" version="1" precursor="true">MPDRITLVRMREIDYILRFPGRFTKADIREAALELRAEINLLDPTVQRTVSSNPRHEGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3A3</accession>
    <name>C7Q3A3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793568.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4979"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73839">
        <property type="protein sequence ID" value="ACU73839"/>
        <property type="gene ID" value="Caci_4979"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4979"/>
    <dbReference type="eggNOG" id="COG5316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_292023_0_0_11"/>
    <dbReference type="OMA" id="FIVENHG"/>
    <dbReference type="OrthoDB" id="50834at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982853" evidence="1">
        <location>
            <begin position="32"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="626"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1060" mass="110759" checksum="237A56F705CD2316" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q439</accession>
    <name>C7Q439_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785193.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0967"/>
    <dbReference type="EnsemblBacteria" id="ACU69899">
        <property type="protein sequence ID" value="ACU69899"/>
        <property type="gene ID" value="Caci_0967"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0967"/>
    <dbReference type="eggNOG" id="ENOG5032UAS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109394_0_0_11"/>
    <dbReference type="OMA" id="TIHRYEM"/>
    <dbReference type="OrthoDB" id="1336167at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="20394" checksum="D5DC5DFF24F69250" modified="2009-10-13" version="1">MRPEPGQVLHFSENPTITRFAPHVAATAQQPEAYVWAVDYERAPDYWFPRQCPRALAWVTPETTEEDRERIIGPGGGLRVHAVEYGWLEQMRTTELYAYRFDARDFRSIGDTAHAHVAETEVVPLGPAERVGDLFELYEEADIQLRVLPTLLPFWDQVITTTLGFSGIRLRNARPASAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q440</accession>
    <name>C7Q440_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785194.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0968"/>
    <dbReference type="EnsemblBacteria" id="ACU69900">
        <property type="protein sequence ID" value="ACU69900"/>
        <property type="gene ID" value="Caci_0968"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0968"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_4_3_11"/>
    <dbReference type="OMA" id="SHRGDDM"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="17216" checksum="F9A6C6B39C8A34A3" modified="2009-10-13" version="1">MVQVLLLCGSVRKGSSNEAMLRLVQEVVGEPDGAVASAVFYEGLGDLPHFNPDLDTDPLPEAVAGLRNAIADADAVLICTPEYAGTLPGSFKNLLDWTVGGTEICDKPTGWINAANPGRGEGAIATLRTVLEYTGAAIVEDACVRIALADPDARKNIGAVLEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q480</accession>
    <name>C7Q480_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ordered locus">Caci_1012</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785234.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1012"/>
    <dbReference type="EnsemblBacteria" id="ACU69940">
        <property type="protein sequence ID" value="ACU69940"/>
        <property type="gene ID" value="Caci_1012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1012"/>
    <dbReference type="eggNOG" id="COG0516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022552_2_1_11"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="OrthoDB" id="532857at2"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="99"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="159"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="343"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="366"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="390"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="253"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU69940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="498" mass="52328" checksum="4A02D4718687DAF7" modified="2009-10-13" version="1">MSDAGLPAKFATLGLTYDDVLLVPAYSEVVPTELSTGTRLSRNITLNVPLISAAMDTVTEARMAIAMARQGGVGVLHRNLSIEAQAAQVDLVKRSESGMVTQPVTVAPDATLAQVDALCAKYRISGLPVIAPDGTLLGIITNRDLRFEVDKSRRVADVMTPMPLVTGPAGISGEDAMKLLAQHKIEKLPLVTGDGKLSGLITVKDFDKSEKYPLATKDENGRLRVGAAIGFLGDSFERAQALMHAGVDFLVIDSAHGHSKVELDMIAKVKAEAPHIDVIAGNVVTGAGGRALIDAGADAIKVGVGPGSICTTRVVAGVGMPQVTAVYEVAEAAREHGVPVIADGGLQYSGDIGKAIAAGADSVMLGSLLAGCEESPGELLFINGKQFKSYRGMGSLAAMQSRGENKSYSKDRYFQGDVESDEKLIAEGIEGQVPYRGPLAAVVLQLIGGLRQSMLYCGAHAIPQLQDAQLVRITAAGLRESHPHDIQMTVEAPNYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4C1</accession>
    <name>C7Q4C1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785275.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1055"/>
    <dbReference type="EnsemblBacteria" id="ACU69981">
        <property type="protein sequence ID" value="ACU69981"/>
        <property type="gene ID" value="Caci_1055"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1055"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="WPKVRRA"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="102"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18839" checksum="6C51991B0DCAA54F" modified="2009-10-13" version="1">MKDDRQAFQDFTAAHGARLFRTAYFLAGGDWHLAEDLTQEALVKVFVAWRRVSRVENPAAYAQTVLTRTFISQRRRKRSTEQPIAEPPERGIEDVDSAVRLTLLAELANLSVRDRAVVVLRYWEDLSVEEVASVLNISSASVRTQSSRALGRLRVALGEVFPERLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4F0</accession>
    <name>C7Q4F0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787212.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3010"/>
    <dbReference type="EnsemblBacteria" id="ACU71919">
        <property type="protein sequence ID" value="ACU71919"/>
        <property type="gene ID" value="Caci_3010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3010"/>
    <dbReference type="HOGENOM" id="CLU_1649068_0_0_11"/>
    <dbReference type="OrthoDB" id="2223152at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17754" checksum="961B29C3374181B2" modified="2009-10-13" version="1">MSEHAVPTADQIRTYLLANGWEVGEFGRAAYLMVTKGHTVRMLHEPTEYDRDKAVFDIALAEGRHPADVHQDILNLRVPAITEEADLGKQMRHRALGAYRLFWKSGGSSVAVVGQLYSGARWYACANWTSPDAERVGLVGTDWSLIERVEEIPDGGDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H3</accession>
    <name>C7Q4H3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787235.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3033"/>
    <dbReference type="EnsemblBacteria" id="ACU71942">
        <property type="protein sequence ID" value="ACU71942"/>
        <property type="gene ID" value="Caci_3033"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3033"/>
    <dbReference type="HOGENOM" id="CLU_1792990_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="16241" checksum="AB1E7889E1F7DAE9" modified="2009-10-13" version="1">MTATPSSTDVFDCIHEIEDHAADLIRGLQVTAARLAEERDSARGERDRAQEERDIAMQMASQATKDLVQARTEFEARLRNRDALIASLRATAETRDDKILRLTAHVRELALANEEQQRQLDAAQQQAAPPARRRRFLRGGDQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Y2</accession>
    <name>C7Q4Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793659.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5070"/>
    <dbReference type="EnsemblBacteria" id="ACU73930">
        <property type="protein sequence ID" value="ACU73930"/>
        <property type="gene ID" value="Caci_5070"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5070"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044048_0_0_11"/>
    <dbReference type="OMA" id="ISISAHY"/>
    <dbReference type="OrthoDB" id="890141at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="412"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="52537" checksum="DA5F4B1B1809F27E" modified="2009-10-13" version="1">MADMTQATFAQHGIRMAQLASGGTAYHMPLVIHLDGDADAGTVAKACAALVERHPLLATALVERDGITYLAPAENAPLLRVADAGERVEDEIAQPFDLDHGPLIRFVLFGRDLVVTAHHTVFDGFSKDVLVRDFLALRGETEPRPLPISFAEHADAERTRVEAALGGARELWKTRWQGPAPVVVRNSVLNSRRAEDGEVIDIELPRIDVPGLTVFEATAAALHVLLFSYGNSRPVTAIDLSTRTPETADLIGPFVNELPLASEPVDDLSFRDFALGVRAELRDIYPFREVPLARAVPRIAPHAALAPISLSFRERSGEIDAGVEWLVFNGAVRGDLQLQIVDTGRILQGSLRFSARAAEHAQPFVDELDALLRSVVQDPDSRLADLLTVKPAVAEAEPVAEPAGASPSEVAGVDGELVEQIREIWQEVLGVARVEVDDDLFDLDGHSLTVTQIAARMRARLGIDISIDALFDNPTIAGALDAVNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q516</accession>
    <name>C7Q516_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5104"/>
    <dbReference type="EnsemblBacteria" id="ACU73964">
        <property type="protein sequence ID" value="ACU73964"/>
        <property type="gene ID" value="Caci_5104"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5104"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_1_11"/>
    <dbReference type="OMA" id="RCRCGAQ"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="41662" checksum="5144EC7BFB871D4F" modified="2009-10-13" version="1">MIQAGAQTTRDLRRRSRATLLSCIYLGRAVSRPELARLAGMSSAAVSNVVSDLISDGLVAEAGSVDSNGGRPRTMLAARPGFGYAVGVDIGETHIHVVLFDWTLSTLATSTHEIRVGRLDPDVVVRLVVSGVRSLLDSTGVPHERLLGIGIGVPGAVQEGERGVVHAPTLGWSGVPLGDALRAELDAPILIDNCARTLGQAEAWRGAGRDARRAVVALWGVGVGAAIAEGSSLAESGSSSTSEWGHAVIEARGRACRCGSHGCLEAYVGATAILDAYLAHPAGKPFTSDGTEAKMAELAARATTGADEAATATFDEAAEYLGIGVGNLINMINPDQVILAGWVGEQLGPLLMPAIREAARRHALPYLFDQTRIDVGELGPGAVALGAATLPVARLLAAGGHFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-02-10" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q585</accession>
    <name>C7Q585_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ethyl tert-butyl ether degradation EthD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7024"/>
    <dbReference type="EnsemblBacteria" id="ACU75854">
        <property type="protein sequence ID" value="ACU75854"/>
        <property type="gene ID" value="Caci_7024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7024"/>
    <dbReference type="eggNOG" id="COG3224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1881997_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02118">
        <property type="entry name" value="TIGR02118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="135" mass="15191" checksum="A787AAEDA37F0020" modified="2009-10-13" version="1">MIATDTTGSTDRTDRTDRTDPSDPAAAPARFIVLWERPTDPEAFERHYRDVHIPLAGKIPGLRSYAICDNPLPVRGEPYFRVAELRWDTMDDLRVGIASPEGDATAKDVEELQRYAECRSFVLGPFEELLEGLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5C4</accession>
    <name>C7Q5C4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795621.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7063"/>
    <dbReference type="EnsemblBacteria" id="ACU75893">
        <property type="protein sequence ID" value="ACU75893"/>
        <property type="gene ID" value="Caci_7063"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7063"/>
    <dbReference type="eggNOG" id="COG0635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027579_1_0_11"/>
    <dbReference type="OMA" id="HIPWCVR"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="4">
        <location>
            <begin position="26"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="43633" checksum="A96181CC07D7F7AF" modified="2009-10-13" version="1">MPGVLPDGEPVPTDGSLPPQALAEPELSRTPLAFYIHVPYCASRCGYCDFNTYTASELGGGASQATYGATAIEEIRLARTVLGGADLPVQTVFFGGGTPTMLPAKDLVALLGAVRDEFGLAPDAEVTTEANPESVNPAYLAELRAGGFTRISFGMQSAREHVLQILDRRHTPGRPEACVREAREAGFEHVNLDLIYGTPGESDDDWRASLDAAIGAAPDHVSAYSLIVEDGTRLAARVKRGELPMIDDDVHADRYLIADEKLAAAGYSWYEVSNWAAAPQGRSRHNLLYWTGANWWGVGPGAHSHVGGTRWWNVKHPSAYSQRVAAGQSPAHAREVLDAEDRRVERILLELRLDSGCDIGILNPAGRKAAIGAAAAGLLDPRSLAEGSAVLTLRGRLLADAVVRDLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J7</accession>
    <name>C7Q5J7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8995"/>
    <dbReference type="EnsemblBacteria" id="ACU77808">
        <property type="protein sequence ID" value="ACU77808"/>
        <property type="gene ID" value="Caci_8995"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8995"/>
    <dbReference type="HOGENOM" id="CLU_2732616_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="71" mass="7520" checksum="D54DC386077149E0" modified="2009-10-13" version="1">MGSAQNQDNGIPGKTLAVALGLGGFTTLLLRVLTTTWPHSIEAGAIIAGLQLFTFVTVRDMALKQSQPPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J9</accession>
    <name>C7Q5J9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797534.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8997"/>
    <dbReference type="EnsemblBacteria" id="ACU77810">
        <property type="protein sequence ID" value="ACU77810"/>
        <property type="gene ID" value="Caci_8997"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8997"/>
    <dbReference type="eggNOG" id="ENOG50343I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1701068_0_0_11"/>
    <dbReference type="OrthoDB" id="2064609at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="16945" checksum="7F64527ED6CCB5C6" modified="2009-10-13" version="1">MPEPPRQTFQYGIWIFDVTAAEHLIATTGQRPIVLLDVPMWAHAYGLDRDDPSAVPLLGPGDGFDRAYAMTTDLSRPLLLATLPTGDGASGHLLIDGCHRLFHAWSTGRATLTAHELDRAETDSILLRRPASDTGQSTRSARQPRIPRPRSGCHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5M5</accession>
    <name>C7Q5M5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_9023</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9023"/>
    <dbReference type="EnsemblBacteria" id="ACU77836">
        <property type="protein sequence ID" value="ACU77836"/>
        <property type="gene ID" value="Caci_9023"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9023"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_3_11"/>
    <dbReference type="OMA" id="LYSEHYR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="112"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="19361" checksum="40133A8C57D77395" modified="2009-10-13" version="1">MVASDRETGDVTVDLLTQTYRDHYSSLLKLAALLLDDLASCEDVVQEAFIRVHSARSRVRDSDKVLAYLRQTVVNLSRSALRRRLIGMRLAPKPMPDMASAEEGAYELLEKDALIHALRGIQRRQREVLVLRYFSDLTEAQVADLLGISIGSVKAYGSRGIEALRVRMEAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5P5</accession>
    <name>C7Q5P5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_9043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797580.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9043"/>
    <dbReference type="EnsemblBacteria" id="ACU77856">
        <property type="protein sequence ID" value="ACU77856"/>
        <property type="gene ID" value="Caci_9043"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9043"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_2_11"/>
    <dbReference type="OMA" id="QVGVAPK"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11954" checksum="AEC1D6143CBCE9C0" modified="2009-10-13" version="1">MGDIRQVTDATFEEEVLKNDKPVLVDFWAPWCGPCRQVAPVLEAIYAEHGEKIDVVKLNTDENPLTQAKYGVRSIPTLNVYRGGEVVKTIVGAKPKALLLKDLADYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5R2</accession>
    <name>C7Q5R2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1083"/>
    <dbReference type="EnsemblBacteria" id="ACU70009">
        <property type="protein sequence ID" value="ACU70009"/>
        <property type="gene ID" value="Caci_1083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1083"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_14_2_11"/>
    <dbReference type="OMA" id="GWCLCSQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="523" mass="56574" checksum="9FF9C555965A7CC0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q681</accession>
    <name>C7Q681_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3179"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72087">
        <property type="protein sequence ID" value="ACU72087"/>
        <property type="gene ID" value="Caci_3179"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3179"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_838607_0_0_11"/>
    <dbReference type="OrthoDB" id="2069514at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043992">
        <property type="entry name" value="SLT_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18896">
        <property type="entry name" value="SLT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982557" evidence="2">
        <location>
            <begin position="41"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="186"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="34384" checksum="CC31CCD2B93B1792" modified="2009-10-13" version="1" precursor="true">MRILRHPGRVRGATAALLGLGLVLAATSTATATTATPAHAAASRHADGGTHRSPHTAGLNHAKAPASTIMCAKVAAKAGFSFNRTVATSLGQEPQIVVAIAVAMAESSCSPSAVNVNSGGSRDRGLWQMNSYYHSEVSDSCAFQIQCNANSAWNISNHGTDWKPWTTFASGAWKTYLAAARSAVSGGFTFQLIDSAAGTCLDADSANHANGAPVRQWACDASDHYQQWTVVSSVGALPILRNLGTGTCLDWDGTKVGNAQPIVQWACDAADASQQFSFLGSGRMNVDGQAQALMQNSHAGTCLAVQGTNHASGAPVWQGTCSASDGYQMWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q747</accession>
    <name>C7Q747_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP synthase protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785429.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1210"/>
    <dbReference type="EnsemblBacteria" id="ACU70135">
        <property type="protein sequence ID" value="ACU70135"/>
        <property type="gene ID" value="Caci_1210"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1210"/>
    <dbReference type="eggNOG" id="ENOG5032DKN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124484_0_0_11"/>
    <dbReference type="OMA" id="KILYVEP"/>
    <dbReference type="OrthoDB" id="1956005at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="16755" checksum="03348F89049BDBAC" modified="2009-10-13" version="1">MQAIDARLLRGAAVPTAAAGAIAVVLCAVLVGSKGLIGALLGSVIVLAFFSVTIVIISRVAQSQPQMLLGYAMLTYLGKIFFLFALMIAFKHTTLFHFRSFGFTMLGLTLVWLAAETRAVLKTKIFYADPSAIPDSLKPVAPARPASTAESEPSPSGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7D4</accession>
    <name>C7Q7D4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein alpha/beta-subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1297</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785516.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1297"/>
    <dbReference type="EnsemblBacteria" id="ACU70222">
        <property type="protein sequence ID" value="ACU70222"/>
        <property type="gene ID" value="Caci_1297"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1297"/>
    <dbReference type="eggNOG" id="COG2086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060196_2_0_11"/>
    <dbReference type="OMA" id="ADLNEWD"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="26811" checksum="EFEF3B4B44E353AB" modified="2009-10-13" version="1">MKVVVCVKQVPDTEAEKRLLPDTLTVDRESSNPVLNEMDEFAIEEALKLVEAHGGEVVVLTMGPDGADAAVRKALSMGADSGILLSDPALAGSDAAATSYAIAQALGTTEFDLVILGSEASDARTSLVPAMLAERLGLPQLTFASKVEIDGTDITVNRLTDYGHDVVKATLPAVVSVVEKINEPRYPSFKGIMAAKKKPIAQLDAAAAGIDAAQVGAAGAWTAVADAAERPPRSAGVKVADEGDGGVKLAEFLSAQKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7M6</accession>
    <name>C7Q7M6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787512.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3312"/>
    <dbReference type="EnsemblBacteria" id="ACU72219">
        <property type="protein sequence ID" value="ACU72219"/>
        <property type="gene ID" value="Caci_3312"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3312"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="OMA" id="CEGYSAY"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="36881" checksum="9DC5F7CE73E18999" modified="2009-10-13" version="1">MLSQAALKSRIDTELRAFVREETGLLEAVDPLLAPVGAQLRAAVADGKRIRAAFCYWGWRAAGQGDTPAMVRAAAAMELVHAAALVHDDLIDDSLLRRGVPTPHVALREATAKAPDPDGAARSLALLVGDLLMAWAGQLFTGSGLPAVYLARARPMWSVLARELIAGECLEVLRTGTETDPQESLTIIRYKTAKYTVEHPLQIGGRLGGASARTLGVFSDYGLPLGEAFQLRDDLLAVFGDPAITGKNNLDDLVAARPTALVAFARQGATPRDRAVLDRLLGREDIGSADLAEVRAILQRSGARGRVEQLIAQRVRRARAALSGAALPRSAAEALHQLAGAVTTRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q879</accession>
    <name>C7Q879_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7238</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795795.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7238"/>
    <dbReference type="EnsemblBacteria" id="ACU76067">
        <property type="protein sequence ID" value="ACU76067"/>
        <property type="gene ID" value="Caci_7238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7238"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OMA" id="RIQMANT"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="28"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="474" mass="49054" checksum="D63ECC692EAF1E9D" modified="2009-10-13" version="1">MPASPEAPAPATTPAPPPSTPNPFSWRFTTPLFLGSALNPVNSSLIATALLPIARGVGVPIGQTAALVTALYLASAIAQPTAGKAAEVFGPRRVFLAGILLVAVGGITGGFAQGLLTLVVSRVLIGLGTSCAYPTAMLLIRRRARDAGLGNPPGAVLGGLQIAGIATASLGLPIGGALVGWFGWRSVFFANVPVALVALAATLTWVSPDGPLQRPLRWREVAARLDAVGIAGFAAAMIALLLFLFSLPTTHWYLLGISVVLWIALVFWELRAAAPFLDVRMLASNKALTRTYLRFGLAMLCLYVVLYGVTQWVEGVRGLSETQAGLLLLPMTLVSGLIVSPVSRRNLVRGPVIAAAVACVVGAVGTLVLSASAWIGWVVVLTLVFGLVMGFAAAGNQTALYAQAPADQLGTAAGLLRTFGYVGSIASSAITGIVFHTSVTDHGVHLIAWIMIGVSVVLLLVSVLDRTLPKRTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8E0</accession>
    <name>C7Q8E0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7299"/>
    <dbReference type="EnsemblBacteria" id="ACU76128">
        <property type="protein sequence ID" value="ACU76128"/>
        <property type="gene ID" value="Caci_7299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7299"/>
    <dbReference type="eggNOG" id="ENOG502ZBPN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071055_0_0_11"/>
    <dbReference type="OMA" id="RWDGWRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021239">
        <property type="entry name" value="DUF2625"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10946">
        <property type="entry name" value="DUF2625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="25911" checksum="614AB33BBD511194" modified="2009-10-13" version="1">MIGRMRELTELIEVDDPAWPELQALFAACPMPLTVFAPDSGESTRGLRQLQVTARSMLGGLTLNTGGLLVDDGWVRVFGAGSGRDGNLPSLAQVNGFPETFDPAWQAAAGLVVAHDVLGGVFALNGMDPAAAGRPGQPGQMIYFAPDTLQWEALEIGHSAWVAWLLSERLEGFYSALRWDGWREEAAAAGPAEGISVFPFLWSKQAEDVATTSRRTVPMSGVLGIAADFAQQIGVGDPGFLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8K4</accession>
    <name>C7Q8K4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1346"/>
    <dbReference type="EnsemblBacteria" id="ACU70269">
        <property type="protein sequence ID" value="ACU70269"/>
        <property type="gene ID" value="Caci_1346"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1346"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_663409_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="42109" checksum="26DBEE219D6D3A1A" modified="2009-10-13" version="1">MTHAHHPADAAAAARAQRDAPTIGTVANTPIPRTRLDERVRDLRTGHLATRLPTAGSKEDRQFLRWTAQVLLTEELCRVELARMQATESALDDDAGAAAAASSLADASASDGSPPADAAPPLDVATPTDATMSAAGFLPADAGPLAAASPPNFATPAAGSLPADVAPPTDATMPAAGSLPADASPPADAATPVDASPPADAATPVDAATPTDATMPVDVVPPVDVAPPAAAATSADVAAPANGPAAPRPLTQAESLHLGSINAAAWSSTSAMSALYDLVTEPSQPAARATDTRPWYRVTHSVAPTALEAATATPTSLGWTTLDDLPAPLAAELRAHPSGSRVGPVHTTLGWHVATITATESRPAEPAPHTEAIDPARLAAFNRWLDERRHALVTLAPGFEHPGDPSQPDNTHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T1</accession>
    <name>C7Q8T1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Limonene-12-epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785640.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1423"/>
    <dbReference type="EnsemblBacteria" id="ACU70346">
        <property type="protein sequence ID" value="ACU70346"/>
        <property type="gene ID" value="Caci_1423"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1423"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107220_1_2_11"/>
    <dbReference type="OMA" id="EWDSWAT"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14932" checksum="3E82E76425C7477A" modified="2009-10-13" version="1">MSTTQQLVLRYFTALAEGDQQTIRDCWAEDGSVWYGGDLPISGTWQGRDQVIDGFLATAFAHLDPEQEIGVKVTNVFGEGEQVLVEWDSWATGKTGRPYHEKNIGVFVVRDGKIVAMREYADTQHWERALVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q902</accession>
    <name>C7Q902_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787615.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3416"/>
    <dbReference type="EnsemblBacteria" id="ACU72322">
        <property type="protein sequence ID" value="ACU72322"/>
        <property type="gene ID" value="Caci_3416"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3416"/>
    <dbReference type="eggNOG" id="COG4291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098677_0_0_11"/>
    <dbReference type="OMA" id="RWIISIS"/>
    <dbReference type="OrthoDB" id="1807879at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009781">
        <property type="entry name" value="DUF1345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07077">
        <property type="entry name" value="DUF1345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="23868" checksum="4273217A39B0D36E" modified="2009-10-13" version="1">MRPDPGPRSVPPAFHASARLKLFVAVAAGALACVVAALGGAGRTSPLIGWDVLAVVFGGWTWRVVWRLDPALTRTHAQEENPSRDLADALLIGASLASLVAVGVVLFGASHAPGNERYWEAALAVFSVFVSWTIVHTVFTLKYARLYYLGTPGGIDFNEPDPPQYSDFAYLAFTIGMTFQVSDTDLQTKEIRRAALRHAWMSFPLGAVIIATSINLVSGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q945</accession>
    <name>C7Q945_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S45 penicillin amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787658.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3459"/>
    <dbReference type="MEROPS" id="S45.003"/>
    <dbReference type="EnsemblBacteria" id="ACU72365">
        <property type="protein sequence ID" value="ACU72365"/>
        <property type="gene ID" value="Caci_3459"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3459"/>
    <dbReference type="eggNOG" id="COG2366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011790_4_0_11"/>
    <dbReference type="OMA" id="THEVPNN"/>
    <dbReference type="OrthoDB" id="186419at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="885" mass="93834" checksum="24CE465CB71840BA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q949</accession>
    <name>C7Q949_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3463"/>
    <dbReference type="EnsemblBacteria" id="ACU72369">
        <property type="protein sequence ID" value="ACU72369"/>
        <property type="gene ID" value="Caci_3463"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3463"/>
    <dbReference type="HOGENOM" id="CLU_3372783_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="34" mass="3617" checksum="3ECA6C4C949A233F" modified="2009-10-13" version="1">MTAVVKNMRDSVGDVLGAWVHGQAWTAPTHAGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9B5</accession>
    <name>C7Q9B5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793990.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5402"/>
    <dbReference type="EnsemblBacteria" id="ACU74261">
        <property type="protein sequence ID" value="ACU74261"/>
        <property type="gene ID" value="Caci_5402"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5402"/>
    <dbReference type="eggNOG" id="ENOG502ZW25">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098984_0_0_11"/>
    <dbReference type="OMA" id="HVCPRQN"/>
    <dbReference type="OrthoDB" id="1271408at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021441">
        <property type="entry name" value="DUF3090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11290">
        <property type="entry name" value="DUF3090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03847">
        <property type="entry name" value="TIGR03847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20208" checksum="296F2B9C0DCD36F6" modified="2009-10-13" version="1">MSRELFVYDPPERFVAGTVGLPGHRTFYLQAASGGRITSVALEKEQVEALAERLDDLLDEVVRRSGGAAPVPAIAPLELSDDKPLEQPVFEEFRVAALALAWDGETQRVVIEAMAPMEGEGEPPLGDMEADGPPTMVVRLTGAQARAFTSRAKAVVSAGRPPCPFCSLPLDPEGHVCPRSNGYRRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q8</accession>
    <name>C7Q9Q8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795955.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7401"/>
    <dbReference type="EnsemblBacteria" id="ACU76227">
        <property type="protein sequence ID" value="ACU76227"/>
        <property type="gene ID" value="Caci_7401"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7401"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="NYEFFGD"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="25538" checksum="D56CFFF56C8321B4" modified="2009-10-13" version="1">MHILVVDDDQAVRDSLRRSLAFNGYEVELAADGLAALEAIAKRRPDAVVLDVMMPRLDGLETCRRLRSAGEDLPVLLLTARDAVPDRVAGLDAGADDYLPKPFALEELLARLRALLRRTQGSLADQSDAPLAFADLTLDPATREVTRAGKPVRLTRTEFNLLELLMRHPRQVLTRAQILEEVWGYDFPTTANSLEVYVGYLRRKTEADELPRLIHTVRGVGYSLRETAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9R9</accession>
    <name>C7Q9R9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7412"/>
    <dbReference type="EnsemblBacteria" id="ACU76238">
        <property type="protein sequence ID" value="ACU76238"/>
        <property type="gene ID" value="Caci_7412"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7412"/>
    <dbReference type="eggNOG" id="COG1487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181601_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="4">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9547" checksum="1EF297AE18AD9550" modified="2009-10-13" version="1">MAGVLDILCELAPVPKDAWRWVDTAQYKLTLKSQHRKSQHRGPGPIDLLVAATAVHHGLTVLHVDNDFVTIAFVLPELRRQDIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA61</accession>
    <name>C7QA61_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785753.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1538"/>
    <dbReference type="EnsemblBacteria" id="ACU70459">
        <property type="protein sequence ID" value="ACU70459"/>
        <property type="gene ID" value="Caci_1538"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1538"/>
    <dbReference type="eggNOG" id="COG2910">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025711_3_0_11"/>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="14"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="25444" checksum="88552C6EF322AC3F" modified="2009-10-13" version="1">MPSERKAGLIVVFGAGGRAGKAVVRESLRRGHAALCVVRDPAKYPGLEALGDEVAVVAGDLTDAGSVASVLAQVPGEVTALVNAVAPFTATPDSVEGFDPDYYVGLVENLSQAARDRDCRAVEIGLFAMLRTGELRLFQDEVAFPAYLRPFAVARLRGLNAWRDQDSEVDWLVLTPPPRLSPDARPTGRYRLGDDLLDRAATPVLFSYDDLAVAVLDQIDTPTVHRCQAAVYGLAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA71</accession>
    <name>C7QA71_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785763.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1548"/>
    <dbReference type="EnsemblBacteria" id="ACU70469">
        <property type="protein sequence ID" value="ACU70469"/>
        <property type="gene ID" value="Caci_1548"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1548"/>
    <dbReference type="HOGENOM" id="CLU_1021920_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="26938" checksum="36D6E4B05989F269" modified="2009-10-13" version="1">MEFAEWVVSGLDQLRLGQLPAGNDFYAVASAGLGGDNRLPAYMNSGDPAARAELVQVIAAAVAANPGFEQQLRDAAAAATQQPQGSVGSMPTQQAQIPVGGMPMTPPQGYAGAKPPFYKTTNGLLVIVAAAVVVVGGGIGLAVSLGGSGSGNLAAILKGTWACKASGAGSEDAGDGPLSFTVGDGTWTAGTASGTWTQNGSSATLHDAGDPTNDVKATHLPSGTGSFDVSVGSASDRSQLVSVHIKGSLSAHKLTIAVTGDSSGNLTLTCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG7</accession>
    <name>C7QAG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792195.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3561"/>
    <dbReference type="EnsemblBacteria" id="ACU72466">
        <property type="protein sequence ID" value="ACU72466"/>
        <property type="gene ID" value="Caci_3561"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3561"/>
    <dbReference type="HOGENOM" id="CLU_1552511_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982956" evidence="1">
        <location>
            <begin position="41"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="17175" checksum="BA7074FE6EBEF775" modified="2009-10-13" version="1" precursor="true">MSPSPSTAVDRRSLLRRAGAAGVAGAAGLAVVGSAGSAEAATGSPTAATACHTAFGTWQVTVYDTAGNVLDQGVQAAFHQDGLLTGANGSGRTIIGSWTPTGAATFTFFAHEQLFDPATGKISGVAHLSHHATLSADGGTFTSQGVITGYTLTGQMIFQQAAAIAATRFTMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAJ1</accession>
    <name>C7QAJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792219.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3585"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72490">
        <property type="protein sequence ID" value="ACU72490"/>
        <property type="gene ID" value="Caci_3585"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3585"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_1_11"/>
    <dbReference type="OMA" id="WTYLQPP"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="2">
        <location>
            <begin position="709"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="811" mass="85237" checksum="3D50207F9DF00EC9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL1</accession>
    <name>C7QAL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792239.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3606"/>
    <dbReference type="EnsemblBacteria" id="ACU72510">
        <property type="protein sequence ID" value="ACU72510"/>
        <property type="gene ID" value="Caci_3606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3606"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_2_0_11"/>
    <dbReference type="OMA" id="AWPSWWA"/>
    <dbReference type="OrthoDB" id="2025630at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="14664" checksum="57CB5D759DC997D3" modified="2009-10-13" version="1">MSTLKPLPEHGTSLFRIVVGFLIACHGASTLFGFPTSGHTVSPLVWPGGVAAALQFGFGVLVMIGLGTRTSAVILSGTMAYAYFSVHQEKALLPMQNGGEPAALFAWAFLMVAIVGPGPLAVDTLRTKAKVGVGIGNEPAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ6</accession>
    <name>C7QAZ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL family lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794198.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5610"/>
    <dbReference type="EnsemblBacteria" id="ACU74469">
        <property type="protein sequence ID" value="ACU74469"/>
        <property type="gene ID" value="Caci_5610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5610"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_4_1_11"/>
    <dbReference type="OMA" id="EDSRWIE"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982969" evidence="1">
        <location>
            <begin position="26"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="33"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="28964" checksum="669E0AF23086C244" modified="2009-10-13" version="1" precursor="true">MLRTFLAFTSLAAAALVAAPTQAQAGGFHKYVALGDSYTAVGDLLKPADGPLGCFRSTVNFPHDLAASLHVADLVDASCGGAVTADMTGPQSVLGGTNPAQFASLTPDTDLVTVGIGGNDIGFGDIVTTCGELSLTSPLGDPCRQHFTSGGTDQLAARIDALAPTIDAVLAGIHQRAPHATVVVVGYLPVLPASWGCWPSVPVAIGDVPWLHGIQQKLNDMLSSRAAADGALSVNPNGVTGRDACQLPWTRWVEPVIPAQPAAPVHPNPAGQSAVAAMIAGRLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB46</accession>
    <name>C7QB46_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796062.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7512"/>
    <dbReference type="EnsemblBacteria" id="ACU76337">
        <property type="protein sequence ID" value="ACU76337"/>
        <property type="gene ID" value="Caci_7512"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7512"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079334_0_0_11"/>
    <dbReference type="OMA" id="SVHAIGY"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="29955" checksum="C6FD040BF22F67DB" modified="2009-10-13" version="1">MSETKLGRILMTGAAGGVGTFLRAGLPGLGWQVRGFDLVRPDEPGATEWVVGDVGDAAALDAAMRDVDVVIHLAGIPVEDRFDRILTSNIDGTYKVFDAALRAGVPRILTASSNHAVGYHERAWYRDAPIGVDVRPRPDTYYGVSKVFMEALGSFYADRHGMQVACVRIGSCFEEPRNRRMLDTWLSPADATRLFHALASAPEFDYEIVYGISANKTGWWDLEPARRLGYDPQDDSDAFAEKIEAAADGAPDPEDPEYRYLGGRFTLAVPPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB71</accession>
    <name>C7QB71_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796087.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76362">
        <property type="protein sequence ID" value="ACU76362"/>
        <property type="gene ID" value="Caci_7537"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7537"/>
    <dbReference type="HOGENOM" id="CLU_1324451_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="22777" checksum="D501CB5BD1B7B7B1" modified="2009-10-13" version="1">MDPRRLEKIYDAVRDELAGLDRFEIEQRACVARARWHAASTSPNANPEQRALAGARAAAIGRILIHLRRTWTDAYDAADHTARALAAERVDPEVAASVRAAGHPVGARVEIVGEERTGIVQQVLVSREEDGYYARWYVVHVAELQLCRAYGCDELETLEPEQAALLPAAQHSAVSFAALAERAERADRGAVTVRHGQRNGRRVLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBB3</accession>
    <name>C7QBB3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7580"/>
    <dbReference type="EnsemblBacteria" id="ACU76404">
        <property type="protein sequence ID" value="ACU76404"/>
        <property type="gene ID" value="Caci_7580"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7580"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_2_11"/>
    <dbReference type="OMA" id="HIVWDWN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="24783" checksum="33D07D20E4D02C4B" modified="2009-10-13" version="1">MPKNHEPLHLVWDWNGTVLNDFEIILRSTNDSFTDHGLPAITAEQYRTLIKMPIRAFYADILGHEPGDEEWEGLDATFHKYYVAYEREARLSDGLPDLFREWSGRGHSQSLLSMYHDDKLVPVVQHHGIAHYFELVQGTLPPRPSRKGLHLQDHLTRLRVDPARVVLIGDSPDDAAAAASVGARVILYSGGFAAAQSLRAVGVPIADSLTAAVALIDEVMAAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE7</accession>
    <name>C7QBE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1603"/>
    <dbReference type="EnsemblBacteria" id="ACU70524">
        <property type="protein sequence ID" value="ACU70524"/>
        <property type="gene ID" value="Caci_1603"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1603"/>
    <dbReference type="eggNOG" id="COG2130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_29_3_11"/>
    <dbReference type="OMA" id="GEVITNC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="35919" checksum="D62716AF54B6D412" modified="2009-10-13" version="1">MSTASTALNYRAIRQARRPQGRPTAADFEIVSSPIPTLAPGEILVRNLAQSVDPYMREAMHWGGWEKGFGLEGRALGRVVASKDPVIAEGSIVFHRHSWATHAVVAKADIRVLTVPEGVPLTAYLGILGGTGLTAYVGLKRVAELQPGEDLFISAAGGGVGTAAARIARVMGAGRLIGSTGSSTKAKHLMEHIGFDAAIDYHAATPLADQLRAAAPDGIDVYFDNVGGTHLEAAISILRHSGRIAWCGAVAQYDDLENPPAAPANLYDIVGKALRLEGFLVRDHLDAREEFESFLIPHIISGAVPVDETIVHGFGNTVDAFVAMLGGGNVGKMVVTFEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC05</accession>
    <name>C7QC05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-mannosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792353.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3722"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72624">
        <property type="protein sequence ID" value="ACU72624"/>
        <property type="gene ID" value="Caci_3722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3722"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_3_2_11"/>
    <dbReference type="OMA" id="MFANFDY"/>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="829" mass="91276" checksum="4AB6AC97C735FBD1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCB2</accession>
    <name>C7QCB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Glutamate synthase (Ferredoxin)</fullName>
            <ecNumber evidence="17">1.4.7.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_5702</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="17"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794289.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5702"/>
    <dbReference type="EnsemblBacteria" id="ACU74560">
        <property type="protein sequence ID" value="ACU74560"/>
        <property type="gene ID" value="Caci_5702"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5702"/>
    <dbReference type="eggNOG" id="COG0067">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_8_2_11"/>
    <dbReference type="OMA" id="TVFRLQH"/>
    <dbReference type="OrthoDB" id="5568at2"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="54"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="941"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="947"/>
            <end position="961"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1550" mass="166634" checksum="39956A9B4CBB101C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD52</accession>
    <name>C7QD52_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Adenosylcobinamide kinase</fullName>
            <ecNumber evidence="8">2.7.1.156</ecNumber>
            <ecNumber evidence="9">2.7.7.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Adenosylcobinamide-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Caci_1841</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CobU/CobP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="8"/>
    <dbReference type="EC" id="2.7.7.62" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1841"/>
    <dbReference type="EnsemblBacteria" id="ACU70762">
        <property type="protein sequence ID" value="ACU70762"/>
        <property type="gene ID" value="Caci_1841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1841"/>
    <dbReference type="eggNOG" id="COG2087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094161_0_1_11"/>
    <dbReference type="OMA" id="DCLTVWL"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043752">
        <property type="term" value="F:adenosylcobinamide kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="entry name" value="PTHR34848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006135">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="16">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="4"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="54"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00012523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACU70762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19666" checksum="5A4A596DF853185D" modified="2009-10-13" version="1">MILGGARSGKSSEAERRLTRLADDAGTAHAALYVATGGRRDGDADWAERVRRHRERRPDSWTTAETTDVAAVLRAATQPVLVDCLTLWLTAMMDDVGAWDDQTWHDTGERELAARFDELEAAWRAATVPVLAVSNEVGLGIVPESAGVRRFRDEQGRLNQRMAAASEGVVLMVAGIAVVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD60</accession>
    <name>C7QD60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1850"/>
    <dbReference type="EnsemblBacteria" id="ACU70770">
        <property type="protein sequence ID" value="ACU70770"/>
        <property type="gene ID" value="Caci_1850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1850"/>
    <dbReference type="eggNOG" id="COG2966">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036601_1_0_11"/>
    <dbReference type="OMA" id="YLYKSAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE" evidence="7">
        <location>
            <begin position="137"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="8">
        <location>
            <begin position="399"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="56380" checksum="A8F41B1D7A41F6E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD99</accession>
    <name>C7QD99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3790"/>
    <dbReference type="EnsemblBacteria" id="ACU72692">
        <property type="protein sequence ID" value="ACU72692"/>
        <property type="gene ID" value="Caci_3790"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3790"/>
    <dbReference type="HOGENOM" id="CLU_3355232_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="36" mass="4068" checksum="5F469948CBBA07E7" modified="2009-10-13" version="1">MNAVRAAYPAIVQLYLVTRPYVDFGHTNSALCRPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD3</accession>
    <name>C7QDD3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3826"/>
    <dbReference type="EnsemblBacteria" id="ACU72726">
        <property type="protein sequence ID" value="ACU72726"/>
        <property type="gene ID" value="Caci_3826"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3826"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="ADWHRDG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="13"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="32466" checksum="85150D0EC02C9193" modified="2009-10-13" version="1">MDTMMALRAHSRGGPEQLVYERAPKPAPAPGEVLVSVHAAAVTFAELGWESIWTREDGTDRTPIIPGHEVSGTVEETTGGSSYEVGDEVYGLIGFDRDGAAAEYVCVPEIGLARKPSSATHEQAAAMALSALTAWQALIDHARLQPQEKVLITGGSGGVGVYAVQIARARGAEVTATGGAAGRELVTRLGAHQYLDYAAGPVDRELSGFDVVLDAAGAGDGEALYRVLRPGGRMILLAAPPNADRAKKHDVDATFFVVSPNGGELAHLASLVDESVLEPIVSQTFSLADGRSAYESGKLPHPPGKTVIIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDM3</accession>
    <name>C7QDM3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_5789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5789"/>
    <dbReference type="EnsemblBacteria" id="ACU74647">
        <property type="protein sequence ID" value="ACU74647"/>
        <property type="gene ID" value="Caci_5789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5789"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="FDTMLAQ"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="156"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="43260" checksum="D867DD13451EC251" modified="2009-10-13" version="1" precursor="true">MSARLKLTFSYAGLVMLAGSLLIGVAWIFALRWLPDNAAVIKNAQQYAPKGMGNSPVVITGPSQSDLMHGFIPAAAVAVAFLLLLGLVGGWFLAGRMLAPLTRIADATRLAATGSLSHRIELEGTNDEFRELADAFDTMLAQLEAHVAEQRRFAANASHELRTPLAITQSLLDAARNDPDRDTGQLIDRLHVVNTRAIDLTEALLLLSRANQRSFAREEVDLSLVAEEAAETLFPMAERRGLTIETIDTSGGAAPPAIGSPALLLQLATNLVHNAIVHNLPGQGTIWVITSAHADYAELTVENTGEQLTPELVATLAEPFQRGSERIRTDHAGVGLGLAIVKSITYAHDGTLTLTPRPTGGLRVTVRLPVRRALTAEAPEARYIPTALRLARIGPAPAHQPGSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDQ7</accession>
    <name>C7QDQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5823"/>
    <dbReference type="EnsemblBacteria" id="ACU74681">
        <property type="protein sequence ID" value="ACU74681"/>
        <property type="gene ID" value="Caci_5823"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5823"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_1_11"/>
    <dbReference type="OMA" id="WIWAETH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="17373" checksum="474CE6B942164657" modified="2009-10-13" version="1">MTHLSPRNSPARPRVLKTVTDVNSWALPTTQTDEHGPCGDDDCGIRDVQDRLGDRWSVLVIVELAKGTRRFGALKAAIPGISQRMLTVTTKRLIRDGMVERTVYPTIPPQTDYRLTPMGESFARAVADLADWSRWHKEAVAVARLRFDLDHPGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE48</accession>
    <name>C7QE48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796361.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7812"/>
    <dbReference type="EnsemblBacteria" id="ACU76636">
        <property type="protein sequence ID" value="ACU76636"/>
        <property type="gene ID" value="Caci_7812"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7812"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="DHYVYTA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="24108" checksum="6876D5177801E40D" modified="2009-10-13" version="1">MNPRVLIADDQVLVRTGFRMILTANGIEVAGEASDGLEAVEAAARLKPDVVLMDIRMPNLDGLEAARRILAADPAIRILMLTTFDLDKYVYDALAAGASGFLLKDVTPEHLVASVRLVDTGDALLAPSITRRLVEKFAAPPAEDAGGAKASPAVHRDLAALTPREREILALMGRGLSNTELAARLVLSEATVKTHVAHIFTKLSLRDRAQAVVVAYETGLVAPGDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QED3</accession>
    <name>C7QED3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786117.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1904"/>
    <dbReference type="EnsemblBacteria" id="ACU70824">
        <property type="protein sequence ID" value="ACU70824"/>
        <property type="gene ID" value="Caci_1904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1904"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="OMA" id="MRYWSIS"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="44684" checksum="2E0FEAE4F02A6DBF" modified="2009-10-13" version="1">MTLADTSTEVLAVPAERGTCPFDPPPAYDLAREQDPVAPVRLFDGSTAWMLTRHQDVRAVLQDRRFSADGTKDGFPFLSPGRRELATGNPTFIRMDDPEHARLRRMLTSDFIIKRVEEMRPQVRAIAVELLDAMTRDRDHADLVAEFALPLPSLVICLLLGVPYQDHAYFQKCSSTLLNANSTAEQVHQARDDLNTYIKQLAESKRDSDDEDIISRLMRREDLSPDEVATMGTLLLVAGHETTANMTSLSILTLLRDPEQMARLRSDPGLIRGAVEELLRYLSIVHTGLPRVATEDVELNGRTIRAGDGVLLMINTANRDSEAFPDADSLDVGRDARRHLAFGFGVHQCLGQPLARAELQIALDVLLTGLPNLRLAVPFEQIPFRHDMLIYGVHRLPIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEE6</accession>
    <name>C7QEE6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786130.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1917"/>
    <dbReference type="EnsemblBacteria" id="ACU70837">
        <property type="protein sequence ID" value="ACU70837"/>
        <property type="gene ID" value="Caci_1917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1917"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_0_11"/>
    <dbReference type="OMA" id="HTNNIFA"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23010" checksum="87B104E3ED31BDC7" modified="2009-10-13" version="1">MRVVLAEDQALLRDGLVRLLTAHGFEVVAAVETGPDLLDALVAEKPDVAVADIRLPPTFKNEGLAAALEARRRVPGLPVLILSQHVEPLYARELLSDSAGAIGYLLKDRVSNVRSFLDAVRTVAGGGTAMDPEVIATMLARRSRDERLGSLTRREREVLAAMAEGHANAGIAGRLVITEKAVSNHINTIFAKLGLLPDLDGNRRVLAVLAYLDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEH7</accession>
    <name>C7QEH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786161.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70868">
        <property type="protein sequence ID" value="ACU70868"/>
        <property type="gene ID" value="Caci_1948"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1948"/>
    <dbReference type="HOGENOM" id="CLU_1329945_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980897" evidence="2">
        <location>
            <begin position="22"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="21338" checksum="AF1C17C577CC92A6" modified="2009-10-13" version="1" precursor="true">MIGLAAAAMLLVPTTATGAPAATAAPDLPAALSALSVAVQATGGQDVSYAIVVHNTTDHAVPDALITQQLPPSLHYITATPPPHHTGHHLTWTLTIPAHGTTRITTTSAADHHLAARPLDHTPQPGTPHRGHHQQQLTTVCVREATGPQSCATEPAAPGPHPLPRRQHAALTTTAAATTAAALLAATRLRRRRRTPRALERAGVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN1</accession>
    <name>C7QEN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792530.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3915"/>
    <dbReference type="EnsemblBacteria" id="ACU72801">
        <property type="protein sequence ID" value="ACU72801"/>
        <property type="gene ID" value="Caci_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3915"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_813586_0_0_11"/>
    <dbReference type="OMA" id="IHGHYTT"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="39184" checksum="F244A83852736412" modified="2009-10-13" version="1">MLIDCHGHFTTAPPALGRWRERQIRAFEESGARVSPDELHIEDQEITAAIEQGQLKLQVERGIDVALFSPGAGKMAHHHGDERTSLDWSRVSNDLIARVCRLFPERFVGVCQLPQSPGEALASSIRSSADELQRCVQESHFVGCLLNPDPSDGYWQAPPLTDKVYYPLYEKMVELDVPAMLHVAMSRNPAVQGTCAHYLAGDTAAFMQLCQSDLFRDFPTLKLVIPHGGGAVPYHWGRYRGFLQDQGRPPLEELLLKNVFFDTCVYHQRGMQLLVDVVPAENILFASEMIGAVRGVDPETGHRFDDTRYLLDSITALGDDDRQAIYGGNALRVFGRLEGVLASRATTAKEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER9</accession>
    <name>C7QER9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3958"/>
    <dbReference type="EnsemblBacteria" id="ACU72839">
        <property type="protein sequence ID" value="ACU72839"/>
        <property type="gene ID" value="Caci_3958"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3958"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_14_11"/>
    <dbReference type="OMA" id="SSHYLVM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="199"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="37141" checksum="C78903278DBB3B01" modified="2009-10-13" version="1" precursor="true">MGRIGGGLLLAGSLLVAGVTLLSYMRDRDLPPPDSRPISLILCLPAVIVGVFLVLSRASVPGWLVNIAPGLAAVLICIPTVVDGRPGPLGPVLLTWTVVYSAYMLAIHVAWMTMGVVAASFAAAAFASRGVDGTDLWIAVTSAILVVFMLVIRLRSQSDRLSAQLIALARADPLTGLVNHRGFEEALGRAQVRHSRDGRPVSLLAIDIDRFKDVNDTWGHPAGDAVLQELAKLLAAYFRSGDVIARVGGEEFAVLISDCGVHEALRRAQGLLGRVREDSLTWDHRITVSIGVATVPDQVEDFDGLHRSADRALYRAKKAGRDGVVSANSGNLVTGSDEADAGRRNPLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEV8</accession>
    <name>C7QEV8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4007"/>
    <dbReference type="EnsemblBacteria" id="ACU72878">
        <property type="protein sequence ID" value="ACU72878"/>
        <property type="gene ID" value="Caci_4007"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4007"/>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013584_2_0_11"/>
    <dbReference type="OMA" id="GFHIQWR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="55615" checksum="EA998F5717034BEC" modified="2009-10-13" version="1">MNTAEPLPDVDDAWMRVLRIQCKLHRWATDDRSRTFDDLFNLVCDPATLVMAWDRVRGNKGSRTAGIDGRTVSRIEGQGVEEFLAGLRESLKSGEFWPVPVKERMIPKANGKLRRLGIPTVADRVVQAALKLVLEPIFEVDFEPCSYGFRPNRRAHDAIAEIHHYASRGYEWVLEGDIEACFDNIDHTALMGRVRERVGDKRVLRLIKAFLKSGIFSEGRAVRDTRTGTPQGGILSPLLANVALAVLDEHFAQVWQETGRTWAARDWHRRRGGATFKLVRYADDFVILAYGSRQHVEDLTADVAQVLSTVGLRLSPTKTAVAHIDEGFDFLGFRIQRHRKRGTDKSYVYTYPSKASMQAVTRKAKAISRQSVEHPLEDVLKQLNWLLKGWAGYFRNSAAKASLNYLGYYTWHRVWRWIRRKHRRVPWKKLKRLYQGSQVGATWWPEHNGIHLFNPATVEIVRYRYRGTRIPNPWSRYAQLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF17</accession>
    <name>C7QF17_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BFD domain protein (2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5917"/>
    <dbReference type="EnsemblBacteria" id="ACU74775">
        <property type="protein sequence ID" value="ACU74775"/>
        <property type="gene ID" value="Caci_5917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5917"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030705_1_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="24"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="2">
        <location>
            <begin position="538"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="629" mass="65834" checksum="F8D1B1419FEBADD6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR7</accession>
    <name>C7QFR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784301.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0051"/>
    <dbReference type="EnsemblBacteria" id="ACU69006">
        <property type="protein sequence ID" value="ACU69006"/>
        <property type="gene ID" value="Caci_0051"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0051"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065779_0_0_11"/>
    <dbReference type="OMA" id="VTICSEL"/>
    <dbReference type="OrthoDB" id="1969674at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="270" mass="28037" checksum="EC72B220963FE807" modified="2009-10-13" version="1" precursor="true">MNSALAGLLAASAVLAFPGPGARRRLETAVLGAPRGPKWRLRMAGAWPTVLSAIALGVLSALLARSMVLAFLVPFGAWRAYRAWTAHTARLAVERRQTEIIELCVTICSELHAGREAREALRDAAVGACPDLAVHLVGPLGTGDDVVTVLRTAAGTPGREALAALAACWQVAEGGAGMTAAIGELSDGLRAERAQRRELDAELAGIRTSARLLAMLPVVGLIIGSGMGLSPIPMLLHTGVGETCLVLGIAFVLGGVMWMDRIARSAEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG51</accession>
    <name>C7QG51_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PKD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4028"/>
    <dbReference type="EnsemblBacteria" id="ACU72896">
        <property type="protein sequence ID" value="ACU72896"/>
        <property type="gene ID" value="Caci_4028"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4028"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071262_0_0_11"/>
    <dbReference type="OMA" id="STWTIDW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="184"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="28516" checksum="B83EB20F4247D679" modified="2009-10-13" version="1">MTCTPGTGSCTIDVNNPGNPGTTPSPSQGSGSGGGSGGSSGGSGATSTPSPEQTLINGDCTYAADPSYVPQPGTESHAGQKGAWYLMTCPDGIKTGGDPNKPVATTTQKMVWLTNPPPAALMLPTPAALADRARSLLTPPKPQIGSNPPVGSPQMVGVPTWAFLSRSLWVPVSAKAEVPGESVTATATPVSVAWDFGDGKSIVCTGPGSQFPPGADPKASSPDCGHTYRISSGNAPGGKFQVTATIIWRVDWVGGGQAGTLNDLTTTATVPVTVNQSQAIVTGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK4</accession>
    <name>C7QGK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">1-aminocyclopropane-1-carboxylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6027"/>
    <dbReference type="EnsemblBacteria" id="ACU74884">
        <property type="protein sequence ID" value="ACU74884"/>
        <property type="gene ID" value="Caci_6027"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6027"/>
    <dbReference type="eggNOG" id="COG2515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048897_0_0_11"/>
    <dbReference type="OMA" id="YHFGGYA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="PTHR43780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="10"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="28003" checksum="08EADAC290DE0573" modified="2009-10-13" version="1">MTDLILHFDNNKPRKLKYNLAEAHKAGATTLLTFGGAYSNHIRAVAAAGRTEGFATIGVIRGEEHLPLNESLAYAASQGMHLTYMDRESYRTKNSPTTRRALHNTFGDFFLIPEGGSNPAAVRGCAELPAEIPHPFDIICCPVGTGGTLAGISAGLSPTQRAIGFAALKGDFLKKEVADLQRQTYGHALTNWHIETDYHFGGYAKIPPHLEAFAAAFGTTHGFEVDRIYVAKMLYGITHMIEANAFAPTTRIVAVITTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR4</accession>
    <name>C7QGR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794673.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6089"/>
    <dbReference type="EnsemblBacteria" id="ACU74944">
        <property type="protein sequence ID" value="ACU74944"/>
        <property type="gene ID" value="Caci_6089"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6089"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_0_11"/>
    <dbReference type="OMA" id="ILRDVWV"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="166" mass="18194" checksum="4DFC59746D4A1703" modified="2009-10-13" version="1">MQRTNFSDLAACSIARTLDVIGEPWSPLILRDVWVGLRRFDQIQGDLGISRKVLTERLNHLVEEGVLERRPYDQRPRHEYHLTQKGTELVDLLMVMTAWGDRWLAGEAGPPVLYRHHACGEISSVDLRCAHCGEPMHAGDVDPLPGPGASAPGASAAAEPADEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV4</accession>
    <name>C7QGV4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">GAR transformylase</fullName>
            <shortName evidence="2">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purN</name>
        <name evidence="4" type="ordered locus">Caci_7981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GART family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796529.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7981"/>
    <dbReference type="EnsemblBacteria" id="ACU76804">
        <property type="protein sequence ID" value="ACU76804"/>
        <property type="gene ID" value="Caci_7981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7981"/>
    <dbReference type="eggNOG" id="COG0299">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038395_1_0_11"/>
    <dbReference type="OMA" id="TGITIHY"/>
    <dbReference type="OrthoDB" id="1815747at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="3">
        <location>
            <begin position="49"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="2">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="10-formyltetrahydrofolate binding" evidence="2">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26856" checksum="59DC933B0126E77A" modified="2009-10-13" version="1">MVTPPVQVGRVRSADNSKHPYEEAAVVVHPEGTKSPPGLVHHRPDRPARIVVLVSGSGTNLQALIDAENAEKARSSAPAFGATVVAVGADRTDIQGLDRAEQAGIPTFALRVKDFATRAEWDRALRDKVAEYEPDLVVSAGFMKLLGADFLAAFDGRVINTHPALSPSFPGMHGPADALAYGVKVTGCTVFFVAGGVDDGPVVAQAAVPVEPGDDVESLHERIKTAERALLVDVVGRLARQGWTIDNRKVTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH30</accession>
    <name>C7QH30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8057"/>
    <dbReference type="EnsemblBacteria" id="ACU76880">
        <property type="protein sequence ID" value="ACU76880"/>
        <property type="gene ID" value="Caci_8057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8057"/>
    <dbReference type="eggNOG" id="COG1524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_492353_0_0_11"/>
    <dbReference type="OMA" id="GYDWLNG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981636" evidence="1">
        <location>
            <begin position="30"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="557" mass="57642" checksum="1D4D43B3D8C5125B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH81</accession>
    <name>C7QH81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784315.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0065"/>
    <dbReference type="EnsemblBacteria" id="ACU69020">
        <property type="protein sequence ID" value="ACU69020"/>
        <property type="gene ID" value="Caci_0065"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0065"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_0_3_11"/>
    <dbReference type="OMA" id="MAIEAKH"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036244">
        <property type="entry name" value="TipA-like_antibiotic-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012925">
        <property type="entry name" value="TipAS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07739">
        <property type="entry name" value="TipAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89082">
        <property type="entry name" value="SSF89082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="29008" checksum="6252D04A2AB97C79" modified="2009-10-13" version="1">MSWSIAQVARMSGVTARTLRHYDDIGLLKPDHVGANGYRYYEEAQLLRLQQILVLRELGLGLSEIAEAIDSEPDTIVALRRQYGRLLVERDRLSRVAETVRRTIAELEGKPQMSVHINRPENLFEGFEESQYEDEARERWPEEFEQAQAKRATMTEEDLERWQREATAAMIRMAEFMAAGTPVDDPAVQDEVHQHYQGICIWWTPNRSAYKCVGQMYVDDERFKANYLKIAEGLAEYQAAAMAAYADARLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG6</accession>
    <name>C7QHG6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HicB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784400.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0150"/>
    <dbReference type="EnsemblBacteria" id="ACU69105">
        <property type="protein sequence ID" value="ACU69105"/>
        <property type="gene ID" value="Caci_0150"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0150"/>
    <dbReference type="eggNOG" id="COG1598">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127098_1_1_11"/>
    <dbReference type="OMA" id="GREIAYC"/>
    <dbReference type="OrthoDB" id="2076579at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031807">
        <property type="entry name" value="HicB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15919">
        <property type="entry name" value="HicB_lk_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HicB-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14458" checksum="577E139D6AC7BC31" modified="2009-10-13" version="1">MTGPATPETYRAIAELDGEWWVVTVPDLRGVYTQGRTYEQARAMARDAIATMLDTAPDRVAVAMEVRLPGHAEDTISEVARARAARDEAAAAEQRKLRESARRLKAAGVKVVDAAVLLGVSKQRVYQLLTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHP9</accession>
    <name>C7QHP9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786367.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2155"/>
    <dbReference type="EnsemblBacteria" id="ACU71074">
        <property type="protein sequence ID" value="ACU71074"/>
        <property type="gene ID" value="Caci_2155"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2155"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089320_0_0_11"/>
    <dbReference type="OMA" id="EWFGEDD"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25690" checksum="770FBAE8E88043CF" modified="2009-10-13" version="1">MHIPGKSRTIEAVVFDVGETLVDESIEYHNWADWLGVPRHTFSAVFGAVVSAGRSHLEAFEYFRPGFDLEAERRARIVAGRPEGYGERDLYPDARPTLAALKDAGYLVLIAANQTTASHRILESLDLPVHLVTTSGMWGGLEKPDPAFFAKVVEVCDEVSRGQGRGPLPGAGSVLYVGDRLDNDLRPAWGAGLRTAFIRRGPWGMVHGDHPDLVAKTDFYLTALDQLPGLLADEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHS7</accession>
    <name>C7QHS7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786395.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2183"/>
    <dbReference type="EnsemblBacteria" id="ACU71102">
        <property type="protein sequence ID" value="ACU71102"/>
        <property type="gene ID" value="Caci_2183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2183"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_7_1_11"/>
    <dbReference type="OMA" id="GWARQEF"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019921">
        <property type="entry name" value="Lucif-like_OxRdtase_Rv2161c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03619">
        <property type="entry name" value="F420_Rv2161c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31329" checksum="FB03AC7B64BF0156" modified="2009-10-13" version="1">MRLGVNVPNFGPATSVEVLERWAHVAEGLGFDMLMMSDHVLVTEDVARGYPGPFHDPFTTLAWLAGRTSRIRLGTTVLIMPYRQPALTAQMAASLHRLSRGRFVLGVGVGWARKEFEALGVPFTKRGALTDEHLDEMHQIWGGGVEGVAPALAPEELPGPPVWIGGNSDAGIRRAVVSGNGWHPLGFTMDWIEDAVGRLKAFADEAGRAVPTLAPRIKLRLTAEPVTDADRQAGIGTLEQVLDDLDRLRALGSEIVVLDPYHGDPAELEQPEEAWRTLAVVAAAWESKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI86</accession>
    <name>C7QI86_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S5A_REDUCTASE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792860.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4267"/>
    <dbReference type="EnsemblBacteria" id="ACU73131">
        <property type="protein sequence ID" value="ACU73131"/>
        <property type="gene ID" value="Caci_4267"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4267"/>
    <dbReference type="eggNOG" id="COG3752">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043418_3_1_11"/>
    <dbReference type="OMA" id="DNYYLAI"/>
    <dbReference type="OrthoDB" id="1734625at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="DUF1295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="PTHR32251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="S5A_REDUCTASE" evidence="6">
        <location>
            <begin position="153"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="275" mass="29823" checksum="51F5806A122421F3" modified="2009-10-13" version="1" precursor="true">MQSESVGSFAAVSGVVLLVLVIVFSAVFVAGVARQRHRYVDAVWGSAFALAAVVTAAMTTEHGDGWRRWLLTLCTIVWGLRLSIHIARRGWGAPEDPRYAAMLGKARGNPTLVAYTKVYLLQAVLVWFISLPVQVGLVATGGSAWGVTPAVIGLLLWLLGISFEATGDYQLARFKADPANHGRLMSEGLWRYTRHPNYFGDACVWWGLFLIGAAAWPVPLTILSPALMTWLLTSGSGKPMVEAHLTNTRPGYADYVARTSGFIPRPPKRISGASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QID2</accession>
    <name>C7QID2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6155"/>
    <dbReference type="EnsemblBacteria" id="ACU75009">
        <property type="protein sequence ID" value="ACU75009"/>
        <property type="gene ID" value="Caci_6155"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6155"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="WQGPADQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="313"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="37894" checksum="8D712007EA9C8F58" modified="2009-10-13" version="1">MDTSVAVRGSGITKTFGDVVALDHVDVSIARGQIHGLVGPNGAGKTTLLGLLLGLAVADQGTLEIFGAPVGRTLAAPDGVSGFVDGPGLYPTLTAKQNLAALVALRHRDAPSTGVDEALHEVGLTEVADDKVRGFSLGMRQRLGLAAALLTKPRLLVLDEPANGLDPAGKKHVHGVLNRLVAGGATVILSSHRMDDLEALCSEVTILSTGRVVFSGPLHKLSDENRELDYRLRVSNAADARTVADGMPGIHIVEGSDAVARADAEAIVVRGKVAAMDELVARIVRADIALRELAPVVSPLEAAFLALTEQTDGEASVPASGQSAGRSPDQHSDAAVKPSAGQSADPIPGQPTDTAVKPSTDQPQEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIW7</accession>
    <name>C7QIW7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 6">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8194</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796742.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8194"/>
    <dbReference type="EnsemblBacteria" id="ACU77017">
        <property type="protein sequence ID" value="ACU77017"/>
        <property type="gene ID" value="Caci_8194"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8194"/>
    <dbReference type="eggNOG" id="COG1209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_9_0_11"/>
    <dbReference type="OMA" id="FTWLDTG"/>
    <dbReference type="OrthoDB" id="1004719at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31851" checksum="5FF8E41FDD2ECD0C" modified="2009-10-13" version="1">MRGIILAGGTGSRLWPITKGVSKQLMPVFDKPMIYYPLSTLVMAGIYEILVITTPEDQVQFQRLLGDGSQWGLDLTYVAQERPDGLAQAFILGEEFIADESVALVLGDNIFHGVGLGRQLRTLNSPAGGVVFAYQVANPREYGVVEFDEAGRAVSIEEKPDKPKSRFAIPGLYFYDNQVVDIAKNLTPSARGELEITGVNVEYLNRGELQVQVLERGTAWLDTGTFDSLVQAAEYVRVIEQRQGYKVGCVEEVAWRSGFITDAQLAELAEPLCKSGYGEYLQHLLDPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW5</accession>
    <name>C7QJW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, B subunit</fullName>
            <ecNumber evidence="3">2.8.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4339"/>
    <dbReference type="EnsemblBacteria" id="ACU73203">
        <property type="protein sequence ID" value="ACU73203"/>
        <property type="gene ID" value="Caci_4339"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4339"/>
    <dbReference type="eggNOG" id="COG2057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019942_4_1_11"/>
    <dbReference type="OMA" id="ANWRVGS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047569">
        <property type="term" value="F:3-oxoadipate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="22086" checksum="75A8ABCF22C6F4A0" modified="2009-10-13" version="1">MSGPLDKQEMAALVARDIPHGAFVNLGIGLPTLVADHLPADSGVVLHTENGMLNMGPAAHGEDIDPDLTNAGKAPVTELPGASYFHHADSFAMMRGGHLDICVLGGFQVSASGDLANWHTGEPDAIPAVGGAMDLAIGARTVFVMMSLFTKSGEPKLVPRCTYPLTGLGCVDRVYTDRAVFDVTPRGVVVREVFGTTVEELADLLEVPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK55</accession>
    <name>C7QK55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794858.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6275"/>
    <dbReference type="EnsemblBacteria" id="ACU75129">
        <property type="protein sequence ID" value="ACU75129"/>
        <property type="gene ID" value="Caci_6275"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6275"/>
    <dbReference type="HOGENOM" id="CLU_935931_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="30585" checksum="707755B11C5EAF54" modified="2009-10-13" version="1">MTPEDAIRDRIAAELAAGRPPLGDLVAAAAAEGRRRKRRTRYAAGAVSAVAVLAVAGAVVRLTPTGTATISQGTGTGPTTTHPAPTSAPSRTPPAKPTAPTSTPSSPSTPPSTTTTTEAGTKLTTTPIVKQVNPGTLRLEKGIYVNFTKDSMSWWEYEGGLTTQYNGSNTWGSDFVSIGAGDRLQGGFYVGDADVAAATVTINGTQHAATVVKVNGTHGWCGLYYLEPPGQPPMKSIQVDVFDATGKDVASSYSGPMSGPPPSSSSPDKARTPPITNIPLGTPFPGVTPTPPPYTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB6</accession>
    <name>C7QKB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794919.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6336"/>
    <dbReference type="EnsemblBacteria" id="ACU75190">
        <property type="protein sequence ID" value="ACU75190"/>
        <property type="gene ID" value="Caci_6336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6336"/>
    <dbReference type="eggNOG" id="COG1687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144816_1_1_11"/>
    <dbReference type="OMA" id="GLHLWRG"/>
    <dbReference type="OrthoDB" id="2078961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003203">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="11190" checksum="1F5C48987BA17CD1" modified="2009-10-13" version="1" precursor="true">MNAHLLASIAVISAVTIALRATGFLVLTRFTDTPVLRVLGTLMPPGVMAVLVVYSISSVDFSQASHAAPVVLGIGATAAIHHWRRNPFLSILAGTAAYVVLLRLLGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE8</accession>
    <name>MSHA2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName>D-inositol 3-phosphate glycosyltransferase 2</fullName>
            <ecNumber evidence="1">2.4.1.250</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 2</fullName>
            <shortName evidence="1">GlcNAc-Ins-P N-acetylglucosaminyltransferase 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshA2</name>
        <name type="ordered locus">Caci_8224</name>
    </gene>
    <organism>
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 3-phosphate + UDP-N-acetyl-alpha-D-glucosamine = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:26188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:58892"/>
            <dbReference type="EC" id="2.4.1.250"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family. MshA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.250" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796772.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7QKE8"/>
    <dbReference type="SMR" id="C7QKE8"/>
    <dbReference type="STRING" id="479433.Caci_8224"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77047">
        <property type="protein sequence ID" value="ACU77047"/>
        <property type="gene ID" value="Caci_8224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8224"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_11"/>
    <dbReference type="OMA" id="HTMAKVK"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008375">
        <property type="term" value="F:acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01695">
        <property type="entry name" value="MshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017814">
        <property type="entry name" value="Mycothiol_biosynthesis_MshA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03449">
        <property type="entry name" value="mycothiol_MshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000400113" description="D-inositol 3-phosphate glycosyltransferase 2">
        <location>
            <begin position="1"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="25"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01695"/>
        </source>
    </evidence>
    <sequence length="427" mass="45405" checksum="27F99BFB50FF4AA9" modified="2009-10-13" version="1">MESLPRRVALLSVHTSPLHQPGTGDAGGMNVYIVELSRRLADLGIEVEIFTRATTGALPPAVDLAPGVLVRHVTAGPYEGLSKEDLPGQLCAFTSGVLRTEAMHEPGYYDLIHSHYWLSGQVGWLAKERWGVPLIHSMHTLGKVKNAALALGDDPEPTARLVGEDQVVDAADRLIANTDQEASELVRLYGADPGRVSTVNPGVDLDRFRPGDKRAARESVGLPPDAAVLLFVGRIQPLKAPDVLLRAAAELIAREPERREKLVVAVVGGPSGSGLAEPTHLHRLARRLGIADVVRFVKPVDQTRLADWYRAADIAVVPSYSESFGLVAIEAQACGTPVVAARVGGLATAVADGRSGTLVAGHDPGDYATAVAGLLDAPHRLADFGENAVEHAARFGWSATAAATADVYSRSIEDLRALRYRELCAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKS2</accession>
    <name>C7QKS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796896.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8348"/>
    <dbReference type="EnsemblBacteria" id="ACU77171">
        <property type="protein sequence ID" value="ACU77171"/>
        <property type="gene ID" value="Caci_8348"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8348"/>
    <dbReference type="eggNOG" id="ENOG502ZFCT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1719048_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16407" checksum="AAE895D93875B0EA" modified="2009-10-13" version="1">MANVEMIRAFIARVLEDGGLVDGRAEADSDGDYQLRYGSALYWVSAGEADDGLGLVQVFGVVLEDVPLSKKLLTAVNEINSGYLWVRCYWAQGRLTVARDLAADTLTADQLTGACAQIGRIADEYDDRFKELVGAGHTVFDGDPGDDDSVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVQ2</accession>
    <name>C7PVQ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786587.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2376"/>
    <dbReference type="EnsemblBacteria" id="ACU71294">
        <property type="protein sequence ID" value="ACU71294"/>
        <property type="gene ID" value="Caci_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2376"/>
    <dbReference type="eggNOG" id="COG4768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132014_0_0_11"/>
    <dbReference type="OMA" id="FSYGVRR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009293">
        <property type="entry name" value="UPF0478"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06103">
        <property type="entry name" value="DUF948"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="14887" checksum="5EC5D9BE0F130ECE" modified="2009-10-13" version="1" precursor="true">MSAGAIVGLIFAIFFAIGVCFFAFVLVRVAEVLKETTKLVAGITQETVPMLNEITDTVKNGNAQLVKVDAITDNVATMSKNVSGLVGTATSAIGGPLVKVASFSYGVRAAITSRKNEDVAKRVKAELKADRKARRADKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ7</accession>
    <name>C7PVZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transport/detoxification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2471"/>
    <dbReference type="EnsemblBacteria" id="ACU71389">
        <property type="protein sequence ID" value="ACU71389"/>
        <property type="gene ID" value="Caci_2471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2471"/>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_13_0_11"/>
    <dbReference type="OMA" id="PMASHGC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="10799" checksum="D8A1C8F3B50B02D6" modified="2009-10-13" version="1" precursor="true">MTELTVIQPEASAASGCSCCATPAAEAVAAAPKESPVSEDQTTAVYTVSGMTCDHCVKSVTEEVGAIDGVQNVDVVLATGQVTVTSAAPLTVEAVEAAVDEAGYTLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW50</accession>
    <name>C7PW50_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_4434</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793027.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4434"/>
    <dbReference type="EnsemblBacteria" id="ACU73298">
        <property type="protein sequence ID" value="ACU73298"/>
        <property type="gene ID" value="Caci_4434"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4434"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_3_11"/>
    <dbReference type="OMA" id="IYYDPML"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="3 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="8"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="127"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="581"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU73298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="668" mass="69730" checksum="23432DDA6DC34EBF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW61</accession>
    <name>C7PW61_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_4446</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4446"/>
    <dbReference type="EnsemblBacteria" id="ACU73309">
        <property type="protein sequence ID" value="ACU73309"/>
        <property type="gene ID" value="Caci_4446"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4446"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_239133_0_0_11"/>
    <dbReference type="OMA" id="NTVYPYE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="13">
        <location>
            <begin position="1"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="111"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="562"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="14">
        <location>
            <begin position="1534"/>
            <end position="1816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU73309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1816" mass="196868" checksum="95D43FA9E45ABF66" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW93</accession>
    <name>C7PW93_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase (quinone)</fullName>
            <ecNumber evidence="7">1.7.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_4478</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinol + nitrate = a quinone + H2O + nitrite</text>
            <dbReference type="Rhea" id="RHEA:56144"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.7.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.5.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793070.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4478"/>
    <dbReference type="EnsemblBacteria" id="ACU73341">
        <property type="protein sequence ID" value="ACU73341"/>
        <property type="gene ID" value="Caci_4478"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4478"/>
    <dbReference type="eggNOG" id="COG5013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_14_1_11"/>
    <dbReference type="OMA" id="PFIHPFN"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02776">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037943">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006468">
        <property type="entry name" value="NarG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01580">
        <property type="entry name" value="narG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="51"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU73341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1242" mass="136316" checksum="8FC1BE113500EB45" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWJ6</accession>
    <name>C7PWJ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6422"/>
    <dbReference type="EnsemblBacteria" id="ACU75276">
        <property type="protein sequence ID" value="ACU75276"/>
        <property type="gene ID" value="Caci_6422"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6422"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_711047_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="264"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="44443" checksum="1C35993624C5EEF1" modified="2009-10-13" version="1">MYFNTRGILMITTRQGVAAHRGGLDLTISLTADQADALGADAHRLVDYLDTVMVQIAAIRTHAEPVLPEARVIPAVPAQQVVSEVTAKDRPIFQGVQWDERVLQEVSALLSMLDGVRDATLRRHAGHHGSIRRAGYAMGVSKATAQSRRNALQAPSPAELWAAGAYGGVRHRKASMPAVMRPWSIAWPGYIPVDVFPPETRARCLVDGVEGSAEALQTPDGVAAAEWLRRSAAALVPFDLDDRGWPLNPAGRTGWTGRRLRHWGENAAANCIVRSNDGYVLMTRCDDLALWAFPGGMIEPGEDRVEAMRRVLREKTGVDVSGVDPKILHRGYREDARATDNAWACSVLSLFVVPRQVPVAAGGDTIEVGWFRVDTAEQLAAELDVRGGLYEAHRPWLQAAIDHLSPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWP7</accession>
    <name>C7PWP7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6477"/>
    <dbReference type="EnsemblBacteria" id="ACU75327">
        <property type="protein sequence ID" value="ACU75327"/>
        <property type="gene ID" value="Caci_6477"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6477"/>
    <dbReference type="eggNOG" id="COG0603">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_433907_0_0_11"/>
    <dbReference type="OMA" id="SRVERDW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="603" mass="64177" checksum="4053BF1C0BB5AC61" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW1</accession>
    <name>C7PWW1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796943.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8395"/>
    <dbReference type="EnsemblBacteria" id="ACU77218">
        <property type="protein sequence ID" value="ACU77218"/>
        <property type="gene ID" value="Caci_8395"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8395"/>
    <dbReference type="eggNOG" id="COG3189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137928_0_0_11"/>
    <dbReference type="OMA" id="AHPEHWW"/>
    <dbReference type="OrthoDB" id="1831995at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="13462" checksum="F7AE89F50FBA1D9A" modified="2009-10-13" version="1">MSGDYRVKRAYDAAAKADGKRVLVDRLWPRGVSREAAELDLWAKDATPSNDLRKWLHGHRDEYGEFVGRYNAELDGDAQQAALAEIRALHAKHTVTLVTAAKDVDDSHVPVLLKRLREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW8</accession>
    <name>C7PWW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8402"/>
    <dbReference type="EnsemblBacteria" id="ACU77225">
        <property type="protein sequence ID" value="ACU77225"/>
        <property type="gene ID" value="Caci_8402"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8402"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="WYDASTF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="28"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="30963" checksum="A84FF6856A967F08" modified="2009-10-13" version="1" precursor="true">MTTNETTNETTDKTTNENANTPVILVLGASGKTGRRVADRLETAGAAVRRGSRSASPPFDWEDPATWPAALEGVASVYVSFYPDLAVPGAPEAVAAFTAEARRAGVRRVVLLSGRGEAEAQRAEEVIAAAGMEWTVVRASWFAQNFSEGAFLDAVNSGEVVLPVGDVREPFIDVEDIADVAVAALTEDGHHEQVYEVTGPQLLTFAEAVRAIAEASGREVAFTSVPLDAFTAYLAEAGEAPEVIEMLAYLFAEVLDGRNAYVTDGVKRAIGRPPRDFADYARTAAAKGVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXJ6</accession>
    <name>C7PXJ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786742.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2531"/>
    <dbReference type="EnsemblBacteria" id="ACU71449">
        <property type="protein sequence ID" value="ACU71449"/>
        <property type="gene ID" value="Caci_2531"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2531"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OMA" id="GVDDNYG"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22659" checksum="09F9E98D5E4DD624" modified="2009-10-13" version="1">MVSGASDRALAADARDTSDVPGADVPGAGLPATTSVALKIAVVGPLGVGKTTFVTSVSDIAPLTTEEPMSGPPPAGVPATKTTTTVAMDFGRISIDERVVLYLFGTPGQERFWFLWDGLVEGALGAIVLVDVRRLEESFDVLERLEDRSVPFVVAANCFPDAPVYPVEELRAAMDLPTPVPVILCDARERSSCRDVLLDLSTYLLELVPNTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ6</accession>
    <name>C7PXZ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Linocin_M18 bacteriocin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4594</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Encapsulin nanocompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the encapsulin family. Family 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793185.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4594"/>
    <dbReference type="MEROPS" id="U56.001"/>
    <dbReference type="EnsemblBacteria" id="ACU73456">
        <property type="protein sequence ID" value="ACU73456"/>
        <property type="gene ID" value="Caci_4594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4594"/>
    <dbReference type="eggNOG" id="COG1659">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089875_1_0_11"/>
    <dbReference type="OMA" id="DSDWQPV"/>
    <dbReference type="OrthoDB" id="1252793at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007544">
        <property type="entry name" value="Linocin_M18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04454">
        <property type="entry name" value="Linocin_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019254">
        <property type="entry name" value="CFP29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1284">Encapsulin nanocompartment</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30172" checksum="DB947ECAA4597A3A" modified="2009-10-13" version="1">MNNLHRDLAPVSDAAWEQIEEEARRTVLRYLAFRRVVDVAGPAGLELGAVGDGHTSAIAAPHDGVHARLRSAQPLVEVRIPFELDRTGIDDVERGAQDSDWQPVKDAAKIAAFTEDRAIADGYAAAGITGLRPFASNAAMLQPEDPADYPTTVARMATQLKLAGVEGPYHLVLGADAYQALSDAVDHGYPVAEHVARLIDGDVIWAPAITGGVLLSGRGGDYQLQLGQDLSIGYESHTAEKVRLYFTQSFTFLPYTAEAAVPLSGMGKDASAKDGKLGRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY74</accession>
    <name>C7PY74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6515"/>
    <dbReference type="EnsemblBacteria" id="ACU75364">
        <property type="protein sequence ID" value="ACU75364"/>
        <property type="gene ID" value="Caci_6515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6515"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="HERRMLA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="5">
        <location>
            <begin position="98"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="856"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1004" mass="107497" checksum="50657CD6704FB8E5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYH6</accession>
    <name>C7PYH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8475"/>
    <dbReference type="EnsemblBacteria" id="ACU77298">
        <property type="protein sequence ID" value="ACU77298"/>
        <property type="gene ID" value="Caci_8475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8475"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="FKLAGMR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="268"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="498" mass="49446" checksum="A812AF135FB2E3F0" modified="2009-10-13" version="1">MSIRATLPEADLCRLSIATPANVLELALPTAVPLADFLPAVLSFAGPELADAGLAHDGWVLQRVGGAPLPAARTLAELQILDGETLYLRPRRATAPTAVFDDVVDGLATAVREREDRLRESAGRWAGPVLGVVALGAGAAGVAAGPGPIGQRAAVAGALAVLVLIGAAVAGRLMAARPTATALGVAAVGWAALGGWLAADTFAHTMTHPESAAALWAGAAALLASAAAAAAVGGAPGGIGDLPSTPRRAANGTAVLDEPDLGTSGLEPFATTAIVAVGTVVAGALGVGFHRALSQTTMISAVIGLGFVLAVPRLAFRLAGQRLPALPATAERIQVDLPPRGQADLWTTSARVERIMAALLLGSGLLAVGGATPAAGHGVLGAIAAADLGIAFLLRARVFARTTLRLLLQSIGMLALAGGAWRAAAVAHTHAVGVTAGIAVGTLVIGMIAASIGPKPQSDDPPYAARAADVAEYFVLTALVPLALGVIGVFGWARGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYT3</accession>
    <name>C7PYT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797130.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8586"/>
    <dbReference type="EnsemblBacteria" id="ACU77405">
        <property type="protein sequence ID" value="ACU77405"/>
        <property type="gene ID" value="Caci_8586"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8586"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109268_0_0_11"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="105"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="21493" checksum="9ADE756A58B4C4AA" modified="2009-10-13" version="1">MALHVDYTAERAFARIIGGLRSARLDAGLSQNALAAGMPVRGRAISEWETRAVEPTLGHLIQWARELGRRLVIVGRDGELRVGPVRQRPGETFEIFERRRLAVPLRNRRLALGMAQGELGALVGVSRDSIQRWELVRVPPRPIAHVVWAQKLGCSLDILVVPDGARRVRRTGFAPAGLAGSTLERPGLRVQRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ99</accession>
    <name>C7PZ99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenate reductase and related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2640"/>
    <dbReference type="EnsemblBacteria" id="ACU71556">
        <property type="protein sequence ID" value="ACU71556"/>
        <property type="gene ID" value="Caci_2640"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2640"/>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116644_0_1_11"/>
    <dbReference type="OMA" id="MVTHPKL"/>
    <dbReference type="OrthoDB" id="1650947at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13448" checksum="BEDC6BC3AFD61EB0" modified="2009-10-13" version="1">MEIWINTACTKCSSALFLLDLEGQEYTVRRYLNDPPSAAELEDVLSRLALEPWDIVRTDEPVAARLGLGSWERSAATRGRWIQALAFHPILIQRPIITADDGTAVVARTREAVRSVLPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZF0</accession>
    <name>C7PZF0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786900.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2692"/>
    <dbReference type="EnsemblBacteria" id="ACU71607">
        <property type="protein sequence ID" value="ACU71607"/>
        <property type="gene ID" value="Caci_2692"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2692"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_11"/>
    <dbReference type="OMA" id="PWRRDPV"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="33670" checksum="83635C91B9184A8C" modified="2009-10-13" version="1">MTSPELNHLQLLTMVGELGSLGRAAEKLGISQPAASKRMDQLERRLGLRLVERNSRGSALTAEGKAVCQWAEKVVASFDALLVGAAALRTDIGNDLRVASSMTLAEHLVPRWIGALQRQLPDVVVSLRMTNSTQVAALAAAREVGLGFIEAPTVPRGLSSRLVGTDRLAIVVGPDHPWARRSGPVGLAELARTRLLVREHGSGTRETLERVLSRAEADPAKPLMVLDANAAMRAAVADGAGPAVMSMMTVRNDLEVGRLVEIPVEGMDLHRRLRAVWSTNRPLTDAESRLLQIAVQSRRLTPTIGPQVRKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI7</accession>
    <name>C7PZI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-L-arabinofuranosidase B catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786937.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2729"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH54">
        <property type="family name" value="Glycoside Hydrolase Family 54"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71644">
        <property type="protein sequence ID" value="ACU71644"/>
        <property type="gene ID" value="Caci_2729"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2729"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029332_4_0_11"/>
    <dbReference type="OrthoDB" id="1832114at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031221">
        <property type="term" value="P:arabinan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019566">
        <property type="term" value="P:arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="PTHR39447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982724" evidence="2">
        <location>
            <begin position="33"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="30"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="48438" checksum="A7425FFE398600A0" modified="2009-10-13" version="1" precursor="true">MNRSRSRAVLAVGASAALVGAGVALSNMTAHAAGAGCSVAYSITSQWGGGFGANVSVTNLGDPVSSWTVGWSFGAGQQVSQAWNATVTQSGAQVSAASMSYNGVLASGGSTSFGFNGTWNNSSNPIPTAFTMNGVACTGGVSSSSSPSTSPSTSPSSSTSVPPPSQEPCDIYAAANTPCVAAHSTTRALYGSYTGNLYQVRRSSDNATANIGVLSAGGPANAAAQDSFCANTSCVITVIYDQSGRGNNLTQAPAGGAAGGPDNLANATSAPTTLNGHKAYGVYVATGTGYRDNATHGIATGDASEGEYAIFDGTHYNGGCCFDYGNAETDSRDDGNGTMEAIYFGNIRVWGYGSGNGPWIMADLENGLFSGVNQHLNSNDPTINYRYTTAMIEGGQNQWAILGGNAQSGNLSTFYSGPRPNVSGYNPMRKQGAIILGTGGDNSKGSDGTFYEGVMTTGYPSAATENAIQANITAAGYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZJ8</accession>
    <name>C7PZJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2742"/>
    <dbReference type="EnsemblBacteria" id="ACU71655">
        <property type="protein sequence ID" value="ACU71655"/>
        <property type="gene ID" value="Caci_2742"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2742"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032284_1_0_11"/>
    <dbReference type="OrthoDB" id="1046754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="49631" checksum="E743A0148306AF7A" modified="2009-10-13" version="1">MAFSGEGSGHGALSWGQRSIWLAMLRQGWLSMGGRIPLPPGTTVEGVADELSFMMGRFQSLRTRLRFDTGGRPTQELSESGEIMLEVYDAATGEDPAAVAAAVEAGYLGTPRDFVNEWPLRMGVVRHLGAPAFLVVITCHLVTDGAGMAVLSRETQERVSEPVAGIQGLELARWQHSPAGQRQSTLALHHLERTLRSVAPRRLPTSEDPREPRHWTGQLDSQALAAVLPAISERTGADSSSILMALFAIAVSRRGLLRPAVIRPLVSNRFRPGLANAVLNLVQSGMCVFDVADRTVDDVIRQARRSFIAANKNTYFDPDGEHALVERIAANQSPDTEPWSPYAWAFFNDRRRSARAESSAPPTPELAEKLRDATTFRWTQKKQNPYEPLFLHLEDNGGSLQLIVEADTHHVSPADNEGLARDIEALGIAAAFDGGLRTGVTAGLPAPCPPRAGPAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZX8</accession>
    <name>C7PZX8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6625"/>
    <dbReference type="EnsemblBacteria" id="ACU75471">
        <property type="protein sequence ID" value="ACU75471"/>
        <property type="gene ID" value="Caci_6625"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6625"/>
    <dbReference type="eggNOG" id="ENOG5033JNT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_815575_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="37266" checksum="2FEE7DC887D2F0BE" modified="2009-10-13" version="1">MSAEAHRAELLRAFRIGPDDLAANRGGRLGGRQLARIRRQEWATAALVLAGLAVLAGILWSVAARPFNAAQLITAGLVAAGLLAAGVAHIRRLRRATAEGEGERESEVACHVGPVKVGLRGRAGWWLSINGQSFHLPVRFWHIGPGLEYRVYVATSANLIVAMEPVVDLTAETLAWERTDDGEFPFAAVYDGQQLRIRVNDFPAEPLYTLIADGREAVDLDDWPAAWSRPKPTPDLLRIAGAEQARRGRVDAIFVADRAYRLCTGETDADQEEFTGGPSRAALDELLGPGREGVRIHWDSARPMHYEVETGESPYVCTVTAYFRGSETAAERVLLQRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q080</accession>
    <name>C7Q080_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795302.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6727"/>
    <dbReference type="EnsemblBacteria" id="ACU75573">
        <property type="protein sequence ID" value="ACU75573"/>
        <property type="gene ID" value="Caci_6727"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6727"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_413994_0_0_11"/>
    <dbReference type="OrthoDB" id="920682at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980504" evidence="1">
        <location>
            <begin position="36"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="712" mass="74269" checksum="5140717BBD94A845" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0D7</accession>
    <name>C7Q0D7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797194.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8654"/>
    <dbReference type="EnsemblBacteria" id="ACU77470">
        <property type="protein sequence ID" value="ACU77470"/>
        <property type="gene ID" value="Caci_8654"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8654"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118511_1_0_11"/>
    <dbReference type="OMA" id="VVFDCAT"/>
    <dbReference type="OrthoDB" id="1876700at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="17176" checksum="3F4FF812FA52B5F4" modified="2009-10-13" version="1">MLGEQTGTLQPAEGALIRLGGDVHSPRELSASDLWSLSRHECEVEFSCRKRGPRRHRFTGPLLLDVAHLAEPAFVPGERKDRLRYLISIRARDGHRVVLSWAEIDPEFANIPVLLGLTRDGDALDAEGPQLVVPGDVCGARHVSGVADVRIRSDSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0N0</accession>
    <name>C7Q0N0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0723"/>
    <dbReference type="EnsemblBacteria" id="ACU69658">
        <property type="protein sequence ID" value="ACU69658"/>
        <property type="gene ID" value="Caci_0723"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0723"/>
    <dbReference type="HOGENOM" id="CLU_2128984_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="10976" checksum="781A6B4111BE606D" modified="2009-10-13" version="1">MGAGGKGDAGRDAVGTVAIGQVEAGRVAISEFVAGGVAVSEAAVGNVVVRRVAVGGVALSKAAAGPVEVGGVAFGRVEVSGFDAGARVSLDQASAACSPSRALWWVRGKLRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q188</accession>
    <name>C7Q188_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Portal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787056.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2854"/>
    <dbReference type="EnsemblBacteria" id="ACU71763">
        <property type="protein sequence ID" value="ACU71763"/>
        <property type="gene ID" value="Caci_2854"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2854"/>
    <dbReference type="eggNOG" id="COG1372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_282958_0_0_11"/>
    <dbReference type="OrthoDB" id="389520at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982780" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="4">
        <location>
            <begin position="456"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="3">
        <location>
            <begin position="638"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="758"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1102" mass="121609" checksum="6C5E5DB1A057814B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K0</accession>
    <name>C7Q1K0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793458.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4869"/>
    <dbReference type="EnsemblBacteria" id="ACU73729">
        <property type="protein sequence ID" value="ACU73729"/>
        <property type="gene ID" value="Caci_4869"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4869"/>
    <dbReference type="HOGENOM" id="CLU_2231750_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="105" mass="10143" checksum="22AB741DAB8DD3AA" modified="2009-10-13" version="1">MSEQGHSGSEGTGAWIAVGVLIAGALLVGGGIVAGSWPVAIVGAAVIVACLLGVAIMGVIGHGAKVPVSFSDEFPATTAGPRATTDGNSAPPIRTDPNSAAPRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1T4</accession>
    <name>C7Q1T4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795363.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6794"/>
    <dbReference type="EnsemblBacteria" id="ACU75635">
        <property type="protein sequence ID" value="ACU75635"/>
        <property type="gene ID" value="Caci_6794"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6794"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_113_1_11"/>
    <dbReference type="OMA" id="VGGIWPA"/>
    <dbReference type="OrthoDB" id="1293707at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038318">
        <property type="entry name" value="KdpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025201">
        <property type="entry name" value="KdpD_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13493">
        <property type="entry name" value="DUF4118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="641"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="891" mass="95423" checksum="4C86DB5A40542367" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y2</accession>
    <name>C7Q1Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage transcriptional regulator, AlpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795411.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6842"/>
    <dbReference type="EnsemblBacteria" id="ACU75683">
        <property type="protein sequence ID" value="ACU75683"/>
        <property type="gene ID" value="Caci_6842"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6842"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_13_0_11"/>
    <dbReference type="OMA" id="RIAPACI"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="8539" checksum="BF1CD5431985FE66" modified="2009-10-13" version="1">MPPRHVPIRSIRSSADDSLLSIPQVITELGISRATFYRWRSLRKGPASLRLPNGSIRIRRSDLDAFLTACEEPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2F8</accession>
    <name>C7Q2F8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785095.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0867"/>
    <dbReference type="EnsemblBacteria" id="ACU69800">
        <property type="protein sequence ID" value="ACU69800"/>
        <property type="gene ID" value="Caci_0867"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0867"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_791679_0_0_11"/>
    <dbReference type="OMA" id="PTVVWID"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="100"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="38264" checksum="BE75264CB9572FBE" modified="2009-10-13" version="1">MNFTILDDHRDVAVDARIAGDGRVLIPIAEVPGALGWERKPQGWCRGDICIPARVAAGVERDGNFVDLAAFAELVDRPYAAVPGLGVAAVGASAAERASALAEGEAPDFELRDVAGVAHRLSDLRGRKVALVFWASWCGCRYDLPEWERQHVALSPEGFSVVSVAIDRRPADAEPWIKEAAATHPALIDADGTVADRYQVLNVPTVVWIDEEGRIARPNDTQFATDLFRSMSGLDSARAMAALERWVRNDDSGLTADDVATYAPQVTAAQQQARTEAALALWLHRAGHPTEAAAHFAEAERLAPEDVTIWRGSMPLLGADPMGDEYFTRREALADAGIPIYRPLPDWQGATKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2I5</accession>
    <name>C7Q2I5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785122.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0894"/>
    <dbReference type="EnsemblBacteria" id="ACU69827">
        <property type="protein sequence ID" value="ACU69827"/>
        <property type="gene ID" value="Caci_0894"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0894"/>
    <dbReference type="HOGENOM" id="CLU_111149_0_0_11"/>
    <dbReference type="OMA" id="LETWRDW"/>
    <dbReference type="OrthoDB" id="1302860at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="21406" checksum="A3FF0D4AA112822A" modified="2009-10-13" version="1">MATLRAVVEIGPEAVEGAAWPVEFADNYRWETLNASTTPETIGTVMAALAEWCRPEDAEPDATPTATEALHWIAEADYLVIRAGIQLTDTTTGTTVNPGCCADLEDWRAWPHTWLGHDPTACIEQAADGLLIHQEKTSQNPVKLPTGTLPALLADLREDLIAFLAAAQTWITTTTADPDLAAAVIATIDRHAAITAPLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2L1</accession>
    <name>C7Q2L1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="9" type="ordered locus">Caci_0921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785148.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0921"/>
    <dbReference type="EnsemblBacteria" id="ACU69853">
        <property type="protein sequence ID" value="ACU69853"/>
        <property type="gene ID" value="Caci_0921"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0921"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_11"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="13716" checksum="7C639BD5A6B29B4A" modified="2009-10-13" version="1">MPTIQQLVRKGRQDKVVKSNTPALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLSSGIEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGSLDTQGVKNRKQARSRYGAKKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q321</accession>
    <name>C7Q321_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787206.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3004"/>
    <dbReference type="EnsemblBacteria" id="ACU71913">
        <property type="protein sequence ID" value="ACU71913"/>
        <property type="gene ID" value="Caci_3004"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3004"/>
    <dbReference type="HOGENOM" id="CLU_1944842_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14430" checksum="2729BDE4F16AA495" modified="2009-10-13" version="1">MTPEEVPDEWLVVAHDGYYDDIHSADHIATWRALRSMLAAVIPLIEQQARELIAAELNDEWGVRRTWTTGDHASHGYAICDTEEGARAALEQYLAIDRAEQSPVESALVRRLVSGWRVVEDDSKEATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q365</accession>
    <name>C7Q365_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="3 9 10">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_4941</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9 10">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="3 9 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4941"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH11">
        <property type="family name" value="Glycoside Hydrolase Family 11"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73801">
        <property type="protein sequence ID" value="ACU73801"/>
        <property type="gene ID" value="Caci_4941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4941"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_1_1_11"/>
    <dbReference type="OMA" id="WRADRND"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033119">
        <property type="entry name" value="GH11_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00777">
        <property type="entry name" value="GH11_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 10" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980566" description="Endo-1,4-beta-xylanase" evidence="11">
        <location>
            <begin position="51"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="13">
        <location>
            <begin position="52"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="12">
        <location>
            <begin position="260"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU73801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="380" mass="40059" checksum="E9F81F84995A1576" modified="2009-10-13" version="1">MSLFDRRAVVAAGCEVDYTDHMRHRRGLLTTLCVVLLAAFGMFLPSTASASTLCNSQTGSNNGYYYSFWTEGSGSACMTLGSGSNYSTSWSNAGNFVAGEGWSTGGRRTVNYSGSFNPSGNGYLSLYGWTTNPLVEYYITDSWGSYRPTGTYKGTVTSDGGTYDIYETTRYNAPSIIGTATFNQYWAVRQAKRVGGTITTGNFFDAWASHGMNMGQYNYMILATEGYQSSGNSNITVDSSNGGGGGGGGTTGALHAVGAGKCLDVPNSSTTPGTQPQIYSCNGQSNQTWTRTSSGQLTVTMNGTTLCLDAYNHQTSPGTKVETWSCNGGANQQWNLNSDGTVTGVQSGLCLDVNGASTANGALVQLWTCSGAANQKWTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q387</accession>
    <name>C7Q387_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ASH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4963</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4963"/>
    <dbReference type="EnsemblBacteria" id="ACU73823">
        <property type="protein sequence ID" value="ACU73823"/>
        <property type="gene ID" value="Caci_4963"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4963"/>
    <dbReference type="eggNOG" id="COG2132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_322560_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982850" description="ASH domain-containing protein" evidence="2">
        <location>
            <begin position="47"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="ASH" evidence="3">
        <location>
            <begin position="698"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="897" mass="88556" checksum="07907E610532DC39" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G1</accession>
    <name>C7Q3G1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795454.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6888"/>
    <dbReference type="EnsemblBacteria" id="ACU75726">
        <property type="protein sequence ID" value="ACU75726"/>
        <property type="gene ID" value="Caci_6888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6888"/>
    <dbReference type="HOGENOM" id="CLU_135445_0_1_11"/>
    <dbReference type="OMA" id="MEEGTIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980573" evidence="1">
        <location>
            <begin position="28"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="14383" checksum="A4AA9DCB0DD6B1AE" modified="2009-10-13" version="1" precursor="true">MTVFVTLLVGVLMMVIGLVTDGGGAVAARADALDEAMSAGRAASQAIDIEALHRDHVIVLDEPAARSAAADFMAATGDHAVISIRQVGAANRVTHVGGDAGPEVTVTVTRTVKTQFLWAVGIDSFAMTATATVTPEPGSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3N7</accession>
    <name>C7Q3N7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ordered locus">Caci_6972</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795530.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6972"/>
    <dbReference type="EnsemblBacteria" id="ACU75802">
        <property type="protein sequence ID" value="ACU75802"/>
        <property type="gene ID" value="Caci_6972"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6972"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086034_4_2_11"/>
    <dbReference type="OMA" id="MGQSLRI"/>
    <dbReference type="OrthoDB" id="1907955at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="9125" checksum="A7F3C3CA54F7656A" modified="2009-10-13" version="1">MTGAFEPWHILLILAITVVLFGAKRLPVAARSMGQSLRIFKSELRQSAQDDAAEAEQASLPPHQDLRHEDHAVTDIPDRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3N8</accession>
    <name>C7Q3N8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6973"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH66">
        <property type="family name" value="Glycoside Hydrolase Family 66"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75803">
        <property type="protein sequence ID" value="ACU75803"/>
        <property type="gene ID" value="Caci_6973"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6973"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_298398_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd14745">
        <property type="entry name" value="GH66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025092">
        <property type="entry name" value="Glyco_hydro_66"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13199">
        <property type="entry name" value="Glyco_hydro_66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981402" evidence="6">
        <location>
            <begin position="48"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="711"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="807"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="8">
        <location>
            <begin position="897"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="783"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1007" mass="104199" checksum="C43A0F271B33828E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3V8</accession>
    <name>C7Q3V8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8903"/>
    <dbReference type="EnsemblBacteria" id="ACU77716">
        <property type="protein sequence ID" value="ACU77716"/>
        <property type="gene ID" value="Caci_8903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8903"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_4_11"/>
    <dbReference type="OMA" id="VLCRDFG"/>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="24202" checksum="3C97E9993C32F99F" modified="2009-10-13" version="1">MDDVLRRTPLFATLDVDAAASLRASMNEIELARGDLLFHEGDPGDSLYVVLRGKIKLGRTSGDGRENLVAVLGPGEMFGELSLFDPGPRSAGATALVDSTLLGLSSDELTPWLATRPDVARALLRAIARRLRRTNDSMSDLVFSDVPGRVAKALLDLSARFGTPAEDGIHVAHDMTQEELAQLVGASRETVNKALADFAGRGWLRLEARAVVLTNVERLSQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q449</accession>
    <name>C7Q449_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0978</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785203.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0978"/>
    <dbReference type="EnsemblBacteria" id="ACU69909">
        <property type="protein sequence ID" value="ACU69909"/>
        <property type="gene ID" value="Caci_0978"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0978"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099045_0_0_11"/>
    <dbReference type="OMA" id="ATWYAGQ"/>
    <dbReference type="OrthoDB" id="1833903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="27637" checksum="074E1E2FD0CB79FB" modified="2009-10-13" version="1" precursor="true">MSTVFNPTIAAITLRGLLGRRRSLLIALPPALLLALTIGLRAATNINSSHDFGWPGVVLGQIGLVTLLPLTAMIIGTSVLGTEVDDASILHLLATPVSRGTVMFTKWIVASGATLVFAVVPISAAAFIATSGYVDNPGPLDMTFTPIKGDTSEAIGVIVAAAVGAIVYSAFFLFLSVVTKRSVAVTLIYILVWESLLTRFVSGLRLLSIGQYELGLADKIGHLPNLGANLTLGTSVIMSVLFTVIALGYGTRRLQSFRVSGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H0</accession>
    <name>C7Q4H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787232.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3030"/>
    <dbReference type="EnsemblBacteria" id="ACU71939">
        <property type="protein sequence ID" value="ACU71939"/>
        <property type="gene ID" value="Caci_3030"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3030"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084779_0_0_11"/>
    <dbReference type="OrthoDB" id="1579971at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="30170" checksum="7EF3F61AB61313A9" modified="2009-10-13" version="1">MVTPEPVLNQHASTIDWVPINKIHTDHDVNTRPVDFTWVDKRVNTFDADKLGVPIVSARANGTFACLDGQNRIELCRRVGWGDQKIECRIFTGLTKAEEATLFLGHNDNRQVGSFHKFAARITAGDSDAVAINNIVTKAGWELSYFVADKRIAAVAALEAIWKASPLDETGYRGATLEATLAIATEAWGHSADAANGQILRGIGGVINRHSNIIDTAGLVRKLAQHRGGAMGLLADARGLHNFAGGTVGSCVAECIVRLYNSHRRTGALPPWRAERGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4T3</accession>
    <name>C7Q4T3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ordered locus">Caci_5021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793610.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5021"/>
    <dbReference type="EnsemblBacteria" id="ACU73881">
        <property type="protein sequence ID" value="ACU73881"/>
        <property type="gene ID" value="Caci_5021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5021"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_1_0_11"/>
    <dbReference type="OMA" id="DDMFLTM"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="24860" checksum="C30CE76C5CF1F6E0" modified="2009-10-13" version="1">MVARPGSTAKQVLVQGRPVDGYPALAPEAARGKELRVTVVGEEVLHRPCREVAEFGTAELLQLVDDMFLTMYVAQGVGLAANQVGVDLRVFVYDCVDDDGARHVGHIVNPKLDRTPEGGQRRLVEAQEGCLSVPGPTRELPRYDHAVLHGVDVHGEPLVLEGEGYFARCLQHETDHLEGTLYIDRMNKKTRRGVLEEMAEVADGVFAERKTRAEELREHFATPSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Y6</accession>
    <name>MSHA1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName>D-inositol 3-phosphate glycosyltransferase 1</fullName>
            <ecNumber evidence="1">2.4.1.250</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 1</fullName>
            <shortName evidence="1">GlcNAc-Ins-P N-acetylglucosaminyltransferase 1</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshA1</name>
        <name type="ordered locus">Caci_5074</name>
    </gene>
    <organism>
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 3-phosphate + UDP-N-acetyl-alpha-D-glucosamine = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:26188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:58892"/>
            <dbReference type="EC" id="2.4.1.250"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family. MshA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.250" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793663.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7Q4Y6"/>
    <dbReference type="SMR" id="C7Q4Y6"/>
    <dbReference type="STRING" id="479433.Caci_5074"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73934">
        <property type="protein sequence ID" value="ACU73934"/>
        <property type="gene ID" value="Caci_5074"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5074"/>
    <dbReference type="eggNOG" id="COG0297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_3_11"/>
    <dbReference type="OMA" id="MIPCGTD"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008375">
        <property type="term" value="F:acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102710">
        <property type="term" value="F:D-inositol-3-phosphate glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01695">
        <property type="entry name" value="MshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017814">
        <property type="entry name" value="Mycothiol_biosynthesis_MshA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03449">
        <property type="entry name" value="mycothiol_MshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000400112" description="D-inositol 3-phosphate glycosyltransferase 1">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="24"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="29"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01695"/>
        </source>
    </evidence>
    <sequence length="418" mass="43698" checksum="50604A58C6EABC5A" modified="2009-10-13" version="1">MTARRGSAPHRIATISVLTSPLAQPGGGDAGGLNVYVVETARRFAETGVQVDIFTRAAAPRLPPIVELCDGVVVRHVPAGPPREVDKGALPRVLGEFTAGMLRAPGDYDVVHAHHWLSGRVGALVARSRGVPLVQSMHSLGLVKNAVLPGEDGSAPPAQIAGESAVIAAADRLVANTAQEADQLIALYGAAPERVHTVHPGVDLELFRPGDRDQARARLGLPHDAFVLLFAGRVQRLKGPDILMRAAAQLLHADLDLAQRLVVAFVGGPSGELQADPDQLTKLATDLGIGEQVRVEPPCPHPELADWYRAATLVVVPSRAETFGLVAVEAQACGTPVVAAAVGGLQTAVRAGVSGVLVEGHDPARYAEVIRALIDDPARLTALRAGALQHAAGFGWSEAVDRLLAVYRSAIEGGRGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5A1</accession>
    <name>C7Q5A1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795598.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7040"/>
    <dbReference type="EnsemblBacteria" id="ACU75870">
        <property type="protein sequence ID" value="ACU75870"/>
        <property type="gene ID" value="Caci_7040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7040"/>
    <dbReference type="eggNOG" id="COG3793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_684574_0_0_11"/>
    <dbReference type="OrthoDB" id="1341696at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031493">
        <property type="entry name" value="Zinc_ribbon_15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17032">
        <property type="entry name" value="zinc_ribbon_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc_ribbon_15" evidence="3">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="TerB" evidence="2">
        <location>
            <begin position="133"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="41337" checksum="983992BA6CA6FE9C" modified="2009-10-13" version="1">MIVWGWKTVFRVIGRGVFSCPTCGADRNYERRKAQRFFTLFFIPLIPLKVVGEFVRCTYCKNDFRDSVLARPTASQFTDLLQNTVRGVMVNILRRGGWEHPGARAIAVQEIVTAGAVGYAEPNLAQDMQVVPEDLSQMLGSLAGQLPDAGREALVAGATRVAAADGPLQPAERAVIDAVGAALGMSQAYVAGIVAAVPAGAVAPAAPAAPAWGTGAQASAGAGAGGGTGAAPVWGTGAQPPVAAGGAGGETMLIQAPQPAQPSSMETMLIQAPQPAPATGAHDAVPPQTPAASGMETMMIQAPQPAPPASGMETMLIQAPQPPQDVPPQPASSMETMLIPTAAPQPPQTIPAPPQTMIDPSSSMETMAIPLPRPVAPADEPTHVTPNDDQGPTGWPPPHQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5B7</accession>
    <name>C7Q5B7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7056</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7056"/>
    <dbReference type="EnsemblBacteria" id="ACU75886">
        <property type="protein sequence ID" value="ACU75886"/>
        <property type="gene ID" value="Caci_7056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7056"/>
    <dbReference type="eggNOG" id="COG1385">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067442_2_0_11"/>
    <dbReference type="OMA" id="TQWKGER"/>
    <dbReference type="OrthoDB" id="1490892at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="26284" checksum="638758D2E6ABDDE6" modified="2009-10-13" version="1">MSTAPVFFWQDTETADRGARVRLDGAEGRHAALVRRLTAGERVDLAGGQGVVAECVVAVAHKDWLELDVRDVVRTPAPEPRVTVVQALPKGDRGETAVETMTEIGVDAVVPWAASRSIVQWKGERGEKALNKWRATAREAAKQSRRAWWPTVRSLHSTAEVAELLAGADQALVLHEDAETPLAGLDVVRQGSVVLVIGPEGSISPQELAAFEAAGARAYKMGPTVLRTSTAGTAAATVVLAKSGRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J8</accession>
    <name>C7Q5J8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797533.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8996"/>
    <dbReference type="EnsemblBacteria" id="ACU77809">
        <property type="protein sequence ID" value="ACU77809"/>
        <property type="gene ID" value="Caci_8996"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8996"/>
    <dbReference type="HOGENOM" id="CLU_2116595_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="114" mass="11825" checksum="55BA40872C58D8BD" modified="2009-10-13" version="1">MTEVPAGIGGDDPLREVLDERVRDAARTLTFSAARMVFDPAKPGQCCAAVRELSHALDRLGDAAGFADLHAGACIEAVAAHLAMSMAAARRRFGDGTPPALPLSVVLASLNEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W4</accession>
    <name>C7Q5W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785355.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1135"/>
    <dbReference type="EnsemblBacteria" id="ACU70061">
        <property type="protein sequence ID" value="ACU70061"/>
        <property type="gene ID" value="Caci_1135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1135"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="31529" checksum="174F40CF9EDFDFBE" modified="2009-10-13" version="1">MTNETPGGVLTLAEDLTLTRVGYGAIQLAGPVAWGPPRDRGEAIAVLRAVVDAGITHIDTSDYYGPYVVNDLIREALHPYPRQLRIATKVGARRTPDRGWPAALSGPELVQAVHDNLRRLDVPALDLVNLRMTDTLAASDIRAPFTVLAELREQGLIRNLGVSNVGIDQLEAARAIAPVVAVQNHYNVAFRQDDDLVDHCAAHGIAFVPFFPLGGFRPLQLEALDHVAGDLGRTPRQVALAWLLHRSPTTLLIPGTSRVAHLRENIDAAAIELPGAALATLEAIAGRPAAKQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q615</accession>
    <name>C7Q615_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785406.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1187"/>
    <dbReference type="EnsemblBacteria" id="ACU70112">
        <property type="protein sequence ID" value="ACU70112"/>
        <property type="gene ID" value="Caci_1187"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1187"/>
    <dbReference type="eggNOG" id="COG1397">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024566_5_0_11"/>
    <dbReference type="OMA" id="WYADDPE"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="31703" checksum="7CE18C63ABC0B3C9" modified="2009-10-13" version="1">MTDDRSLARAVASLRGLAVGDAVGACYFIPLNQPLLTDRRLPPDPWFWTDDTEMACSVLAVLRDHGRADQNALARSFAAHHDFDRGYGAGVNRMLRLIRQEGADWREQAEGMFDGKGSWGNGAAMRVAPLGAWYGSADLDRVVAEATASAEVTHTHPEGVAGAVAVAVAAALATDTSSSGLSGHDFLDEIAERTPPGMVRDGIGNAMTLLPLTDPRSAAASLGNGRYISAPDTVPFCLWIAAKHLDDFETAFWDTACVGGDIDTTCAIVGGIVASRVGVAGIPAVWLKRCEALPEWVGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q638</accession>
    <name>C7Q638_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787337.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3135"/>
    <dbReference type="EnsemblBacteria" id="ACU72044">
        <property type="protein sequence ID" value="ACU72044"/>
        <property type="gene ID" value="Caci_3135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3135"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_1_11"/>
    <dbReference type="OMA" id="VVHTDYV"/>
    <dbReference type="OrthoDB" id="1186478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="26144" checksum="F312DDBDBCA91A22" modified="2009-10-13" version="1">MTEGAVLLLGGRSEIGLKVAERLAAGRTVVLAARRSEALEAEAARVKAAGAADVHRVEFDADEVAAHPELMTKVFADAGPVGVVVVAFGILGDQERAERDPAHAVQVVHTDYVAQISILTVLATLLKAQGRGDLVVFSSVAGLRVRRANYVYGSAKAGLDGFASGLGDALHGTGVHLLLVRSGFVVGRMTEGMSPAPLSSTPDQVADAVVGALRKRRIRVWVPWALRPMYFVARLVPQAVWRRMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q689</accession>
    <name>C7Q689_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787388.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72095">
        <property type="protein sequence ID" value="ACU72095"/>
        <property type="gene ID" value="Caci_3187"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3187"/>
    <dbReference type="eggNOG" id="ENOG50344YT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1701065_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980626" evidence="1">
        <location>
            <begin position="28"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="15591" checksum="DE6E943C77D569C1" modified="2009-10-13" version="1" precursor="true">MRSIKTTVTAAAVLTAGFVLSAPVAHAATAPQAKNTCHSAIATAEKARHAYDAAAADLKKQIADGGHPGTAEEKNVTDLMAAAKTAVWNAVQSCKGMEDHHRRMHMHPRGAMHTGVGSTSQGVSGGEMAGGVGILGAAGAGALALRRRRSGSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D4</accession>
    <name>C7Q6D4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1,4-alpha-glucan branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3233</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3233"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72140">
        <property type="protein sequence ID" value="ACU72140"/>
        <property type="gene ID" value="Caci_3233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3233"/>
    <dbReference type="eggNOG" id="COG0296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004245_3_2_11"/>
    <dbReference type="OMA" id="HFREWDE"/>
    <dbReference type="OrthoDB" id="227746at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="5" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="166"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="638" mass="71200" checksum="8D0F15EA509B6157" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6E5</accession>
    <name>C7Q6E5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3244"/>
    <dbReference type="EnsemblBacteria" id="ACU72151">
        <property type="protein sequence ID" value="ACU72151"/>
        <property type="gene ID" value="Caci_3244"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3244"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032284_1_0_11"/>
    <dbReference type="OMA" id="DIRNAHE"/>
    <dbReference type="OrthoDB" id="1046754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="29"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="451" mass="50466" checksum="AA490C6FD2146E1A" modified="2009-10-13" version="1">MQRTIMVPFHGDGAGTEELTWGQWTVWRMMNGFGAVFMVGGAMKLEEGTTLQHIEHLLAFVMRRHESLRTRIRTESDGTPRQVVSSSGEVGLEIVDIEDGEDPAAVAEALRERYEFEPFDIAEDWPVRMAVVRKDGVPDHFVAMYPHMAIDAYGFDALVGDLANLDRETGAELAERGGIQPRDLARKQRESSAQRQGQASLRYWERWLMEVPARRFNGPYTGSEQRWWDSTYDSRAAFLAVGAISARTGMHSGPVLLAAYAVALEKVTKAGPSAIRMVVSNRFRPDFARSVSVVAQPGLCVFDVRDCTFDEAVVRAWHAQIATGKNAYYDPRKLAELRERVEKERGEQLDLMLYFNDRRKTLAQPVAEPEAVADAEQMWDALPQSRLTWGIRSNAPDVKAYLDVNGSPDTVNLTLRSDTQALTPSEQVTVLRTMEEILLAAAFDPQCPTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P3</accession>
    <name>C7Q6P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5219"/>
    <dbReference type="EnsemblBacteria" id="ACU74078">
        <property type="protein sequence ID" value="ACU74078"/>
        <property type="gene ID" value="Caci_5219"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5219"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008552_0_0_11"/>
    <dbReference type="OMA" id="KNEAGWD"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1176" mass="120513" checksum="AECA844C2ED3ECA4" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6R3</accession>
    <name>C7Q6R3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793827.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5239"/>
    <dbReference type="EnsemblBacteria" id="ACU74098">
        <property type="protein sequence ID" value="ACU74098"/>
        <property type="gene ID" value="Caci_5239"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5239"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_0_11"/>
    <dbReference type="OMA" id="FCKSLCT"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="29354" checksum="CBFF0E827FC87520" modified="2009-10-13" version="1">MSQLSADEIAAYLDRLGVAGPVRPDADALRVLHRAHVLTIPFENLSIHLPGEEVSLDLGALVDKIVTRRRGGFCYELNGLFAALLEAVGFGVERLSARTYSAMRGAFTYPLDHLALRVTDAAGEVWLADVGFGKHSEMPLRYAERGEQSDAFGTFRLVETTEGELDVLLDGAPQYRVDPRALALADFEPGRWWQVTSPASLFRQALTCSLPTPDGRVTLRGRKLITTDAGGKRERVIRDDAALLAAYRDLFGIALTVVPTVVPAAKTHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q717</accession>
    <name>C7Q717_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795758.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7201"/>
    <dbReference type="EnsemblBacteria" id="ACU76030">
        <property type="protein sequence ID" value="ACU76030"/>
        <property type="gene ID" value="Caci_7201"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7201"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_1_11"/>
    <dbReference type="OMA" id="VQVQPWD"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982592" evidence="1">
        <location>
            <begin position="26"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="45882" checksum="AFC11DC09A82D7C8" modified="2009-10-13" version="1" precursor="true">MRIRTSAALAVGSVLVLGATACSSAASKSSGPAGSGSGTQPAAVAGAGSGAGKTLTVWYMDGDLSDAATKAINDKFTAATGAQVKVAIQQWDGINTKIATALAQDNPPDVIEIGNTDVPLFAASSGLTDITSALPQLQADQHWLPGLAGPATVDGHNYGAPLFAGNRAVIYNKKIWAAAGITAAPTTFAQLTADLDAIKAKNTAPDFSAFYFPGRYWYGAMQFVWDAGGQLASQAGGKWTGQLESPQAQQGLQAWKTFIGKYSAGASQDVDTTAPDFNTLFAQGKTATILNSNVNKILKVDPSLTDQIGTFPFPSATDGKTQPVFLGGSDLAVAAKSKNQALALAYLKAATDPAVQASAIVGIDHWIPASTEVIDQTISSLPDVSKAFFTAAKTSVATPAVAGWATIESDKSINDFFADIATGRKSPADAAKTLDAHLNQALNAPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q771</accession>
    <name>C7Q771_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785453.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1234"/>
    <dbReference type="EnsemblBacteria" id="ACU70159">
        <property type="protein sequence ID" value="ACU70159"/>
        <property type="gene ID" value="Caci_1234"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1234"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="832" mass="88909" checksum="14AAF13A0C6895D6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7H0</accession>
    <name>C7Q7H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3256</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787456.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3256"/>
    <dbReference type="EnsemblBacteria" id="ACU72163">
        <property type="protein sequence ID" value="ACU72163"/>
        <property type="gene ID" value="Caci_3256"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3256"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034004_1_1_11"/>
    <dbReference type="OMA" id="LYTPNIM"/>
    <dbReference type="OrthoDB" id="402639at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="161"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="39370" checksum="B2CBEE769B1126BC" modified="2009-10-13" version="1">MDILGIDHVEFYVGDARQAAFFLCTAFGFHIAGHGGPETELPRQRSLLLAHGDSRVLLTSALSSGHPADGYVSRHGDGVGVIAFATVDATGAYEEAVAAGATAVEAPRTYKADGDTVTTASVGGFGDVVHRFVERRGAAFWPGAIEPQPAPARTEPELVRAIDHAAVLVPDGELEPTVEYYQRVFGFKLIFEEYVEVGAQGMYSQVVQSPSGGATFTIIQPDMSRDSGQIDDFLAWHGGAGVQHLALSTDDIVATVKSFAANGAGFAQTPGAYYDVLPERIGATDLPVDQLRPLGILVDRDHWGQMYQIFSKSMHIRRTFFWELIERHGAKTFGTSNIPALYAAKERELAGVRDSVDVGAMGTAGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q880</accession>
    <name>C7Q880_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7239"/>
    <dbReference type="EnsemblBacteria" id="ACU76068">
        <property type="protein sequence ID" value="ACU76068"/>
        <property type="gene ID" value="Caci_7239"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7239"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_15_1_11"/>
    <dbReference type="OMA" id="HINHARS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="15807" checksum="8FE4DF005E4C506C" modified="2009-10-13" version="1">MTEAQPEPRRETANHLRIAIGAFRRRVDEAAIAGELTNPQLTALSRLDRLGPMTTTALARREQITPQAMGTTISGLEKLGLIARTPHTTDARQSILTLTPEGLAALHTGRNAVTDKITAALEESFTDTDLATLTAAASLIERLAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Q8</accession>
    <name>C7Q8Q8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785617.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1400"/>
    <dbReference type="EnsemblBacteria" id="ACU70323">
        <property type="protein sequence ID" value="ACU70323"/>
        <property type="gene ID" value="Caci_1400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1400"/>
    <dbReference type="eggNOG" id="ENOG5033M8Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112849_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16456" checksum="B63BFD1F8EBB6B52" modified="2009-10-13" version="1">MTYKIFDLPTHILVIHLVVVGIPVAALATIAIAVRPQWRSGKAGLAVVVIDALAVVGTYVARISGEQFYNHNPGFSQLKQIVDHKNLGLTLIWYVLGLLVAAILLILAEKYERPPLTTVFAIVATIVAVAAVVQTVRVGDAGARATWSSYITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8V3</accession>
    <name>C7Q8V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785662.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1445"/>
    <dbReference type="CAZy" id="CBM16">
        <property type="family name" value="Carbohydrate-Binding Module Family 16"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70368">
        <property type="protein sequence ID" value="ACU70368"/>
        <property type="gene ID" value="Caci_1445"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1445"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_3_0_11"/>
    <dbReference type="OMA" id="ATTVYNW"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980699" evidence="2">
        <location>
            <begin position="41"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="50"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="597" mass="59895" checksum="87A8F43C42163F6A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X2</accession>
    <name>C7Q8X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3386"/>
    <dbReference type="EnsemblBacteria" id="ACU72292">
        <property type="protein sequence ID" value="ACU72292"/>
        <property type="gene ID" value="Caci_3386"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3386"/>
    <dbReference type="eggNOG" id="ENOG50309MX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055999_0_0_11"/>
    <dbReference type="OMA" id="GRISQHD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="34564" checksum="4AD1D56A715349AB" modified="2009-10-13" version="1">MSPALSIDRDGPGDLARLLASGPFPEALRAAIAGSGLSLDRLQYRLRRQGTPISLATLSSWQSGRRQPERAASMAALHRLEEIVGVPPGALAALVGPRRARGRSVYTGAPDLVEVWDWDPIAGLLGEFDTSSDDVLVRLSQYERLTVGPDGRLRELYSRALVRAATNDVRSSIVIDQAAEGTASVVRPLRGCTLGAVRSRPDAGLTIAELLLPHPLQRGELLLMEYVVEFTAPFPRDNDTYRRLRLPVREYIIDVEFTRPALPARCVQFVASLDDESVMTERVLTLDERDRVCALGVDLDPCVFGVRWEWSETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X5</accession>
    <name>C7Q8X5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787588.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3389"/>
    <dbReference type="EnsemblBacteria" id="ACU72295">
        <property type="protein sequence ID" value="ACU72295"/>
        <property type="gene ID" value="Caci_3389"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3389"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084148_0_0_11"/>
    <dbReference type="OMA" id="MHRAMGF"/>
    <dbReference type="OrthoDB" id="1670016at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31081" checksum="3ABEBBF63D5FAED7" modified="2009-10-13" version="1">MESESACGLPASRYARWRERFSRSVIGNVWRGGTQLELVRRSMAFATLGLVALAPLLVVVAAVNPASQQGLGQWVVDGMGLPPNTATPVLHLFASHHQATGQVGVLGLALLAAFGLAFVTDVQRGYQGIWEIPPESWRQAWRRAVWLAAMIGYLGFEMESGALLRHGPLASAGRIVIVATAGLFFFWWGQYFLLAGRVPWGWLLPGALATVAGLSGLRAFSVLVFNPMMVSSARDYGMVGVVLVVLSWLIGVGFVIFGGALAGRHYCEHRVGIRADREPVLDTEPGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9B9</accession>
    <name>C7Q9B9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793994.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5406"/>
    <dbReference type="EnsemblBacteria" id="ACU74265">
        <property type="protein sequence ID" value="ACU74265"/>
        <property type="gene ID" value="Caci_5406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5406"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="WVYRHRT"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="405"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="46538" checksum="274BD8D821C10C52" modified="2009-10-13" version="1">MTRLFAYPGYARFWSADTVSTFGTYVATVALPTLAVIVLKASDTQVGLLNGARWTPYLLFGLLAGVVADRYRRRPILVATDLVRGVLLAVVAVLAAVHIVNIYELAGFVFVFGILSLLYDAAHQSYLPRLVPPASLTVANARLEQTTALAQTTGPFIGGALVAAIGAPLAMMIDAASYLVSGLTLATIRVPEPVPHAESRNLKAEMREGLRFVYRDPVMRAYALTLHARFLFASVIGTVFTLFVLRDLGAGSPRAAFGLGLVLAAGGVGAVIGNGMAQRLGRGGVGRVMVAERLAEPVAWSVAALAVSGAAGWAMVAGAQFLAWLALGASGPNEMAYRQSATPDRLQGRVNATVRSLNWGMITFGAPVGGLLAQHLGYRPALWAGVAGMAASGVVAALSPMRRARVTETPEDPEKPEILADPVNPEDPEPQEGTGENTAKGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9W9</accession>
    <name>C7Q9W9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7463</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7463"/>
    <dbReference type="EnsemblBacteria" id="ACU76288">
        <property type="protein sequence ID" value="ACU76288"/>
        <property type="gene ID" value="Caci_7463"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7463"/>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046535_0_1_11"/>
    <dbReference type="OMA" id="WDAFVTM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983055" evidence="4">
        <location>
            <begin position="36"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="35404" checksum="0C85ECAC429F69DB" modified="2009-10-13" version="1" precursor="true">MRQGAHRGRMVAVAAAVVVIGLSAGCGSSKSSSSAASSVGSVAAGGNGGSGGGLSGAAPKAGAAPASGNSLAKTPVAGRSLVYTASMTVRTKDVAGATANAETLAASNGGFVGDEKSLSGTVADVKGLTQSTVTLRVPSTAFDKVIGQLDSGGVVQDETRSASDVTSQVVDTSTRITAQQASINRITDLMKNAANLSDVVTLESELSRREADLESMQAQLATLNDQVSMSTITVTFLVPEAPAPHPVVKHQNALQRGLHDGWQAFTGTVKVLLVIVGALLPFAVLVAVLWWPATRVMRFVERVRARQRQKARTGSSVFAPATVPANVPAGVAAGGGDQPGSTTGAASDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAE4</accession>
    <name>C7QAE4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin carboxylase</fullName>
            <ecNumber evidence="2">6.3.4.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3538</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792172.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3538"/>
    <dbReference type="EnsemblBacteria" id="ACU72443">
        <property type="protein sequence ID" value="ACU72443"/>
        <property type="gene ID" value="Caci_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3538"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_1_11"/>
    <dbReference type="OMA" id="IGPKHYS"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="119"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="513"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="591" mass="62877" checksum="61CE704A036F05E1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBF4</accession>
    <name>C7QBF4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785825.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1610"/>
    <dbReference type="EnsemblBacteria" id="ACU70531">
        <property type="protein sequence ID" value="ACU70531"/>
        <property type="gene ID" value="Caci_1610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1610"/>
    <dbReference type="eggNOG" id="COG1171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_11"/>
    <dbReference type="OMA" id="DALQPCG"/>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="40"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="32598" checksum="3DC62065258F9DBA" modified="2009-10-13" version="1">MSTPVITEADVKTAADRIASRVRRVTVAPADPGTVPRASAVWLAAEYMQHGGSFKARGALNLALHHLENGTMPEEGITIASGGNAAIAAAWAGRAAGIKVTVFLPATAPTIKIAKLRALGADVRLEGTVYAHALEASIQHADETGALLSHAYDNPLVAAGAGTCAAEIRDLIPDVDTVMVAVGGGGFFAGTAAAMFPHGVRVIAVEPENCRALNAALEAGGPTDVDVESVASDSLGARRVSETAYQLATNPLATSVLVTDEQIIAARTALWEHRRVLVEHGAAAALAALLSGRYSPSEGERIAVVLCGANTDPSDLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBJ0</accession>
    <name>C7QBJ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA polymerase IV</fullName>
            <shortName evidence="13">Pol IV</shortName>
            <ecNumber evidence="13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dinB</name>
        <name evidence="18" type="ordered locus">Caci_1646</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 13">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1646"/>
    <dbReference type="EnsemblBacteria" id="ACU70567">
        <property type="protein sequence ID" value="ACU70567"/>
        <property type="gene ID" value="Caci_1646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1646"/>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_340325_0_0_11"/>
    <dbReference type="OMA" id="RSCALHH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01113">
        <property type="entry name" value="DNApol_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 13 18" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 13" id="KW-0515">Mutator protein</keyword>
    <keyword evidence="4 13 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="15">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="16">
        <location>
            <begin position="704"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="744"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="386"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="464"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="539"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Substrate discrimination" evidence="13">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACU70567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="834" mass="87319" checksum="8C31C191C704AD16" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBV8</accession>
    <name>C7QBV8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="12">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">trpB</name>
        <name evidence="14" type="ordered locus">Caci_3675</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="12"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3675"/>
    <dbReference type="EnsemblBacteria" id="ACU72577">
        <property type="protein sequence ID" value="ACU72577"/>
        <property type="gene ID" value="Caci_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3675"/>
    <dbReference type="eggNOG" id="COG1350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042858_0_0_11"/>
    <dbReference type="OMA" id="MLHQTII"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006316">
        <property type="entry name" value="Trp_synth_b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF6">
        <property type="entry name" value="PTHR48077:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500824">
        <property type="entry name" value="TrpB_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01415">
        <property type="entry name" value="trpB_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="46"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU72577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="43268" checksum="97D7C9DBEC9CB6E1" modified="2009-10-13" version="1">MLHPGTKEPITESDLAPLFPAELIAQEFTKDRDVDIPGAVLDVYKQWRPAPLVRARRLEQALDTPARIYFKYEGVSPAGSHKPNTAVPQAYYNKLAGVAKLTTETGAGQWGSSLSLACSYFGLECEVFMVKISYQQKPYRRGLMQTYGATVHASPSELTQAGRDALAADPDNPGSLGLAISEAVEAAVVGGDDVKYALGSVLNHVLMHQTIIGQEARLQLELAEDYPDIVIGAAGGGSNFGGLALPFLREQLEGGRSVRAIAVEPSSCPSLTEGKYDYDFGDTAGLTPLAKMHTLGHDFRPPAIHAGGLRYHGMAPIISALKEAELLEARAVPQTACFEAGVTFARNEGIVPAPESTHAVRVAIDEALRAKEEGVSRSILFSLSGHGHFDMQAYADYFAGDLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC67</accession>
    <name>C7QC67_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5656</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794244.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5656"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74515">
        <property type="protein sequence ID" value="ACU74515"/>
        <property type="gene ID" value="Caci_5656"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5656"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018242_0_0_11"/>
    <dbReference type="OMA" id="GRTWTIK"/>
    <dbReference type="OrthoDB" id="228378at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981538" evidence="1">
        <location>
            <begin position="30"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="686"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="824" mass="85079" checksum="1D78B27B75D07101" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCR6</accession>
    <name>C7QCR6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative phage repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796254.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7705"/>
    <dbReference type="EnsemblBacteria" id="ACU76529">
        <property type="protein sequence ID" value="ACU76529"/>
        <property type="gene ID" value="Caci_7705"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7705"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_11_0_11"/>
    <dbReference type="OMA" id="WWVLGDN"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014124">
        <property type="entry name" value="Pept_S26A_Sod_Ni_maturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02754">
        <property type="entry name" value="sod_Ni_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="3">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13468" checksum="86685E0ED7CC4FDC" modified="2009-10-13" version="1">MVAFVRLVPRAAKGWSVHRVTGASMVPALRDGDFVLVRRARPGRIRPGDVVVARHPARAGELLIIKRAARREGAGWWLLSDNEFVTSDSREFGAVPEDSVLARAVLRLRDPARIARIPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCV7</accession>
    <name>C7QCV7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase, PaaI subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785961.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1746"/>
    <dbReference type="EnsemblBacteria" id="ACU70667">
        <property type="protein sequence ID" value="ACU70667"/>
        <property type="gene ID" value="Caci_1746"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1746"/>
    <dbReference type="eggNOG" id="COG3396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070585_0_0_11"/>
    <dbReference type="OMA" id="NGDFAHT"/>
    <dbReference type="OrthoDB" id="1389523at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011882">
        <property type="entry name" value="PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037834">
        <property type="entry name" value="PA_CoA_Oase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02158">
        <property type="entry name" value="PA_CoA_Oxy3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27822" checksum="3EDA682B7D2CD590" modified="2009-10-13" version="1">MTATTESTPLVAQYALQLGDDALILSHRLSEWCAHSPELEEDVALANLALDLLGQARTLLTYAGSLEGAGRSEDDLAFLRTEREFRNVLLVEQPNGDFAATIARQLYFATYQSELYAALCDSTDPELSALAAKAVKEVAYHRDHAVQWTLRLGDGTEESHRRMQAGLEQLWPYTAELFAADAVATELVAAGVAVDPRTLRPAWEASVAGVVEAATLTMPADGWQPRGGRAGRHGEGFGLLLGEMQALHRQHPGAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCW3</accession>
    <name>C7QCW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1752</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785967.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1752"/>
    <dbReference type="EnsemblBacteria" id="ACU70673">
        <property type="protein sequence ID" value="ACU70673"/>
        <property type="gene ID" value="Caci_1752"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1752"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016513_0_0_11"/>
    <dbReference type="OMA" id="GNVQCLD"/>
    <dbReference type="OrthoDB" id="433393at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AidB_N" evidence="8">
        <location>
            <begin position="15"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="187"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="293"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="550" mass="58802" checksum="B3C8626A26D082C6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD59</accession>
    <name>C7QD59_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786063.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1849"/>
    <dbReference type="EnsemblBacteria" id="ACU70769">
        <property type="protein sequence ID" value="ACU70769"/>
        <property type="gene ID" value="Caci_1849"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1849"/>
    <dbReference type="HOGENOM" id="CLU_1203059_0_0_11"/>
    <dbReference type="OrthoDB" id="1230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983116" description="DUF11 domain-containing protein" evidence="2">
        <location>
            <begin position="46"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="3">
        <location>
            <begin position="54"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="23968" checksum="B7CBBC09279DC6AF" modified="2009-10-13" version="1" precursor="true">MRTMMRSAAAVGVVVAAAMTVGTMSTLAARAGSGALPTLPTDASASSTGNGVRVEISDDTRSAHSGDVVDYTVRVDNDSPTSYPALEVYHLVPAGFQLVDSSPNATQQDRTMRWTANVPSGHTVVFSDQVMAGTVEESDHLTPHVRDAKTGTRTDQFTSTACARSSSTGPALACGTVREQLTDGPDAIAGVAGPNGKHWQPGLLGIALLVALYAGFRSFFRKRGEQGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDU3</accession>
    <name>C7QDU3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794446.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5859"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74717">
        <property type="protein sequence ID" value="ACU74717"/>
        <property type="gene ID" value="Caci_5859"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5859"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_3_11"/>
    <dbReference type="OMA" id="HEFGTIA"/>
    <dbReference type="OrthoDB" id="1573900at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="12"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="558" mass="61484" checksum="76D4844F886B81AD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE93</accession>
    <name>C7QE93_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integration host factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786078.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1864"/>
    <dbReference type="EnsemblBacteria" id="ACU70784">
        <property type="protein sequence ID" value="ACU70784"/>
        <property type="gene ID" value="Caci_1864"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1864"/>
    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151796_0_0_11"/>
    <dbReference type="OMA" id="KDNPVVG"/>
    <dbReference type="OrthoDB" id="1950120at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="10965" checksum="ED944543B35E069B" modified="2009-10-13" version="1">MALPTLTPEQRAAALAKAGEVRRARSEMLADVKAGKLSLKAVLDRAAKGEEMVKKTKVTALIKALPGYGPAKAAKLMADAEIDENRRIGGLGDRQRQALLAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEB4</accession>
    <name>C7QEB4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ste24 endopeptidase</fullName>
            <ecNumber evidence="12">3.4.24.84</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_1885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="12"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786099.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1885"/>
    <dbReference type="EnsemblBacteria" id="ACU70805">
        <property type="protein sequence ID" value="ACU70805"/>
        <property type="gene ID" value="Caci_1885"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1885"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025947_1_1_11"/>
    <dbReference type="OMA" id="LPFKIYK"/>
    <dbReference type="OrthoDB" id="1918093at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="11">
        <location>
            <begin position="6"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="171"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="42365" checksum="EE56CB432F6395CB" modified="2009-10-13" version="1">MDYAAQDFTPEQIERARAYKRSVRPLRIISTILGLAVPLVLGLTPAGAGLVRVAGDVAGGGWVARALLGSVALSLLGLVLRLPLSMWSETVSRRWGLSKRGWGLFAADTAKGFLIGVVLTAAAIGALYALMRHAGDAWWVWAALAAALLALLGSFIMPVLIEPLFNKFKPLPDGPLRERLMALVEQSGVPVKDILVSDSSRRTTAANAYVSGLGKTRRLVVWDTTTDSLDTGEVAAIAAHELGHAARRDVLTGTVFGAVGAALGVAVLAAALHWSPLLDAAGVDHAEDPRSQALVRAVLVLIGLIGEPWGLAYSRYIEGRADGYALDLFRDPDTIVRMERALAVQNIADLEPRRWEVLLRYTHPPIPARIAHARGWAAQTGVAIPKPLSAPSKDPGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEQ7</accession>
    <name>C7QEQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3944"/>
    <dbReference type="EnsemblBacteria" id="ACU72827">
        <property type="protein sequence ID" value="ACU72827"/>
        <property type="gene ID" value="Caci_3944"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3944"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="487"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="705" mass="75476" checksum="976BBA580634727C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QES0</accession>
    <name>C7QES0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72840">
        <property type="protein sequence ID" value="ACU72840"/>
        <property type="gene ID" value="Caci_3959"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3959"/>
    <dbReference type="HOGENOM" id="CLU_3041634_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="5739" checksum="2A6634E3B5E40DF5" modified="2009-10-13" version="1">MAFRTESEIRNRLDSYELINPGQPGPAMDLAPSPRTTSLYAGVGRKSCAGSTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEU1</accession>
    <name>C7QEU1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792590.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3985"/>
    <dbReference type="EnsemblBacteria" id="ACU72861">
        <property type="protein sequence ID" value="ACU72861"/>
        <property type="gene ID" value="Caci_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3985"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_4_4_11"/>
    <dbReference type="OMA" id="QELKYRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="56"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="144"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="22091" checksum="4C31E6E10681FD97" modified="2009-10-13" version="1">MAAALNGCCGNPIPNRFRTFPVGGTQESPDPGSGLGSGERFEGQVRELARPMGEQAYRILGDRSLAEEVVQEALLQMWLHRDGFDSARGSLGGWALAIVRHVAVDRVRSEQAAARREALFAVRHAATPYDEVVDAVERVQDYARIRTLLDDLTAVQREAIRLVYFDNLSAAQAAERLGIPVPTLRTRLRDARQALELILGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEZ3</accession>
    <name>C7QEZ3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5893</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794480.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5893"/>
    <dbReference type="EnsemblBacteria" id="ACU74751">
        <property type="protein sequence ID" value="ACU74751"/>
        <property type="gene ID" value="Caci_5893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5893"/>
    <dbReference type="eggNOG" id="COG1933">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111077_0_0_11"/>
    <dbReference type="OMA" id="AGFQFEF"/>
    <dbReference type="OrthoDB" id="1167594at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DZANK-type" evidence="4">
        <location>
            <begin position="173"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="23732" checksum="0E8DA2EAE9166B24" modified="2009-10-13" version="1">MADNTLWFSNNHRDYSNQYGNDAGFEFEFYCQRCSDTWRSGFEPYKAARAAGWIRRASNMASGAASSIGWDVAEGVDGLVQSGWHKARDASFKEAITSAEQHFNRCGRCTSYVCARCYSTERGLCTNCAPDLAAEVESARTHGLVDAATSRARDVGATMAAEVDVATQKQLVCLSCGHETHGAKFCPECGAKQNAEPGPCGGCGSPVPTGSKFCPECGHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEZ5</accession>
    <name>C7QEZ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794482.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5895"/>
    <dbReference type="EnsemblBacteria" id="ACU74753">
        <property type="protein sequence ID" value="ACU74753"/>
        <property type="gene ID" value="Caci_5895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5895"/>
    <dbReference type="eggNOG" id="COG1062">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_11"/>
    <dbReference type="OMA" id="AGWCQTD"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="10"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37468" checksum="50C20B693B0D3740" modified="2009-10-13" version="1">MRAAVLFEIGTQTLEVRDDVTLADPGAGEVRIRVHATGVCHSDLSAMTGVLPQPAPFVPGHEGAGEVVAVGEGVDKVAVGDHVIVCWNPPCGDCSACRRGQGNLCVNIFFGMTMTPHFAIDGAAVYGFAGSGTFAEELVVPWQCAVKIPDDVPYEIAALIGCGVTTGVGAVINTAEVEPGSSVAVIGAGGVGISVIQGARIAGAAEIVAIDPVESKHEAALRFGATKAVKPEDADAAKAEVTGRDGFDYVFEVVGRSALVKQAYGLTRRGGTVTVVGAGKNDDTVDLNMFQLFFDNKKILGSYYGGADPRQEYGRLIALWRAGRLDLEGMITARLKLDDINQALELLRTGAAIRTIIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF47</accession>
    <name>C7QF47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794534.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5947"/>
    <dbReference type="EnsemblBacteria" id="ACU74805">
        <property type="protein sequence ID" value="ACU74805"/>
        <property type="gene ID" value="Caci_5947"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5947"/>
    <dbReference type="eggNOG" id="COG4214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_2_1_11"/>
    <dbReference type="OMA" id="LAVWMDT"/>
    <dbReference type="OrthoDB" id="1254678at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="45852" checksum="7F29BABEEBFF872D" modified="2009-10-13" version="1">MTATENPTGTATATGETVPETGAAGTLLAYGRNRLERARGGELGSMPAVAGLVVLVIFFAIVQNGFLSLYNIANLVTQAAPIIVLAMGLIFVLLLGEIDLSAGTASGVCAALMAVMIVRHSLPWYVAVLAAIVTGAVLGFLIGWLRAKVRIPSFVVTLAAFLSFQGIVLMQVGKAGSISLPDQAAKPIITLEGYNNNLMPLWLGWVMLAVVAGGYALVKLRIAVSRRSAGLEAEPALVTFAKTLLMLILGAVFVYLLGENRAIQQNAFFNNLKIEGIPWVVLLLIVLTVGLTFLLSRTRYGRHVYAVGGNDEASRRAGIRVDRIRISVFVICSTLAAVAGVVQASQLESVASNFGAGNTLLLAVGAAVIGGTSLFGGRGRIMDAVWGGLVVAVIQNGMGDLIKGANSQAWQWIVTGLVLLLAAGFDATSRRVGRGDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFI1</accession>
    <name>C7QFI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796483.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7935"/>
    <dbReference type="EnsemblBacteria" id="ACU76758">
        <property type="protein sequence ID" value="ACU76758"/>
        <property type="gene ID" value="Caci_7935"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7935"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_11"/>
    <dbReference type="OMA" id="WEALAQP"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="28592" checksum="A079984A5F6F8B38" modified="2009-10-13" version="1">MPESREYPLLAVRRTSDGVLTVTLDDPDRRNAMTAPMTASWERLMREIARDEEIRCVVVTGAGSAFCAGGDLGWIGAEPGAPVEKLRDKMLPFYRIWLSLRDLPVPTIAAVNGPAVGAGACLALACDLRYAVDTATFAVPFTKLGMHPGMAATWLLPEVVGMATARELLYTNRAVSGAEAVALGVFNRVFPAGDFPGEIERIASDVAAGAPIAVKLTKQALIGDGHESFEAALRWEALAQPITMATEDLQEGLAAQRERRVPRFTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFY3</accession>
    <name>C7QFY3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe/B12 periplasmic-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2040"/>
    <dbReference type="EnsemblBacteria" id="ACU70960">
        <property type="protein sequence ID" value="ACU70960"/>
        <property type="gene ID" value="Caci_2040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2040"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038034_2_7_11"/>
    <dbReference type="OMA" id="FSWYGSR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="26163" checksum="55620F8E6B61979C" modified="2009-10-13" version="1">MRVISLVPSLTEAIAATAPDLLVGVTAWCSHPADLDVERIGGTKNPDVHRIVALAPDLVVANEEENRRDDLDALREAGISVLVTTIRTLDEAFSELDRMLTAGCGLDRPAWLDQAEAAWSFPAPAIEEAVPAIIPIWRRPWMVLGRDTFAGDVLARLGVRNIYADHAERYPKIPLPELLAASAELVVLPDEPYAFDASDGPDAFPDLPSALLSGRHLTWYGPSLVEAPDVLRRQLDAAAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFZ0</accession>
    <name>C7QFZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2047"/>
    <dbReference type="EnsemblBacteria" id="ACU70967">
        <property type="protein sequence ID" value="ACU70967"/>
        <property type="gene ID" value="Caci_2047"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2047"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_28_1_11"/>
    <dbReference type="OMA" id="AYQGMSL"/>
    <dbReference type="OrthoDB" id="1826886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20655" checksum="274C8712B145D48E" modified="2009-10-13" version="1">MTDSKRGGKRERLASAAAEVFHQQGVERTTLNDIAQAADVPLGNVYYYFKTKDQLVEAALGAHRSRLAELTDQLDALPDPAVRLKTLIAGWVDQREVAARYGCPFGTLATELDKREDGLDQTAAGVLRALLDWAEEQFRQLGRADARDLAVDLVAAYQGMSVLANALRDPEVMTAQGRRLEGWIDTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL7</accession>
    <name>C7QGL7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6040"/>
    <dbReference type="EnsemblBacteria" id="ACU74897">
        <property type="protein sequence ID" value="ACU74897"/>
        <property type="gene ID" value="Caci_6040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6040"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094953_0_0_11"/>
    <dbReference type="OMA" id="VVPHLYA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="31"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="23525" checksum="EB9054FEAF3E85B8" modified="2009-10-13" version="1">MDAEGGTAPSADRLPPGQRMQRGEWPVLHYGPVPRFKPATWDFRVTGATAEEQGGIWFHDQFAALPTIDVVADFHCVTKFTMLDAPWRGVAARTVLDLAPPAPEATHVTVWAEYGYSANLRLEDLLRDDVVFATHHDGAPLTPEHGFPLRLILPHLYAWKGPKWVRGIEYLTADRRGFWEERGYHNIGDPWKEQRYSYQEDPGDGPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR8</accession>
    <name>C7QGR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6093"/>
    <dbReference type="EnsemblBacteria" id="ACU74948">
        <property type="protein sequence ID" value="ACU74948"/>
        <property type="gene ID" value="Caci_6093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6093"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="MKHAGAG"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="344"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="443" mass="45946" checksum="D61E6651536566D1" modified="2009-10-13" version="1">MMTTSPVSAPRAWARQPLVQDAALASGLLAVCLPLNNPVAVVRTVAAGPLGGAWGGAITAWGWWTATAFTLAGVALRRRWPLPMLGVCSLAVAVHLALLSVVPTVVDLSAVVLLATVAARCPRRVSAVALGGMLVLMAGWCFDGARLGRPVNGLPTFNVEVVHHLDQPGASGADEIVDQAKGSSTWSAVALLGSVLLAAWAIGSANGSRRDYLHQLHARAADLERERDQQAALAVAAERGRISREMHDVVAHGLSLIVIQAQGADAALDNRPADTRSALRAIVRTGRDSLADMRRVLAALGEVEDAWHPQPGLAQLPGLLEQVRTAGTAVRLRVAGTPAALPSAVDLSAYRIVQEALTNVMKHAGAGASADVVVEYSDTEIAVEVGDDGRIPNGHAGPGVGGGNGLRGMDRRVQLLGGRLSAEPEAGGGFRVRATLPIEGRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV8</accession>
    <name>C7QGV8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796533.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7985"/>
    <dbReference type="EnsemblBacteria" id="ACU76808">
        <property type="protein sequence ID" value="ACU76808"/>
        <property type="gene ID" value="Caci_7985"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7985"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_2_11"/>
    <dbReference type="OMA" id="LHMACCA"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="21347" checksum="0F2A37C8394B391A" modified="2009-10-13" version="1">MDPKMLTAFLAVDLLLVFTPGADWAFVIAAGLRDRSVVPAVAGLIAGYAGYTLLAVAGLAVAVASSGAVLTVLTVAGAGYLVWLGWGVLSQPAVLGASVEDASAMSVTRRQIMVKGAGISSLNPKALLLYFSLFPQFIRPANGWPVSAQIGLLGALHMTACTVVYLGVGVLARTLLTTRPAAGRAVTRVSGVMMIAIGGLLLLERLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGY4</accession>
    <name>C7QGY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8011"/>
    <dbReference type="EnsemblBacteria" id="ACU76834">
        <property type="protein sequence ID" value="ACU76834"/>
        <property type="gene ID" value="Caci_8011"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8011"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_859679_0_0_11"/>
    <dbReference type="OMA" id="CAFEEIG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="211"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="32642" checksum="8E8E673002F88CB0" modified="2009-10-13" version="1">MDLRTWQEAGIRAGSYSARHRGRSPFSPLRPAPIAIGSLSTAAIAAFAFVAPGVLHGTPAGASSTVLDGAPNRVAPMAPGHGGDAAPGFVTVTAPASSSSDSPATPTSTATSEQAAVSSSPAPYTEHTPTMSGSSSRPSQPQPSQSQAPPSTSPTAPTSPASPTAPSQRPTEPPTIPPSAPVVPPPTSSTTTTPFNSSAAVSSALSEIGRARGQQGVSLMSVNTLLTKAAKVHSVDMARTGDFSHIGSDGSDPFSRAANVGCFSLSQELIAHGKPGDDVIGALMRDPASKRALLSFWNSTIGVSAQLDPATGDVYWTIELGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH19</accession>
    <name>C7QH19_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8046"/>
    <dbReference type="EnsemblBacteria" id="ACU76869">
        <property type="protein sequence ID" value="ACU76869"/>
        <property type="gene ID" value="Caci_8046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8046"/>
    <dbReference type="eggNOG" id="COG1920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_203151_0_0_11"/>
    <dbReference type="OMA" id="MQATSFT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="8395" checksum="FEC6AC1F37956F9E" modified="2009-10-13" version="1">MYNQSVTRKEAQGTARLFDPTTHTGTVLLDDGTEIAFDAPAFTAGGLRLLRIGQRVKMHLDDGRITALTLVTLPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH76</accession>
    <name>C7QH76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU69015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0060"/>
    <dbReference type="EnsemblBacteria" id="ACU69015">
        <property type="protein sequence ID" value="ACU69015"/>
        <property type="gene ID" value="Caci_0060"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119412_0_1_11"/>
    <dbReference type="OMA" id="GRIWSYV"/>
    <dbReference type="OrthoDB" id="1756670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022002">
        <property type="entry name" value="DUF35_Znr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12172">
        <property type="entry name" value="DUF35_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF35_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="54"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14813" checksum="D8A83356283A60A1" modified="2009-10-13" version="1">MTRPLPVTGRDNAYYWEGVAKGDVLIQKCTACGSLRHPPSPMCPDCQSLDWTTVKATGHAVLHSYTICHHPLPPWEEGPYAVVLIDLDMEDSDARPRIVCGTRGIANEDLRIEMPLSLVFEDGLVFAGPAQEGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHD7</accession>
    <name>C7QHD7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784371.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0121"/>
    <dbReference type="EnsemblBacteria" id="ACU69076">
        <property type="protein sequence ID" value="ACU69076"/>
        <property type="gene ID" value="Caci_0121"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0121"/>
    <dbReference type="eggNOG" id="COG4420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077948_0_2_11"/>
    <dbReference type="OMA" id="IVWMTVV"/>
    <dbReference type="OrthoDB" id="1597938at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41386">
        <property type="entry name" value="PTHR41386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="19155" checksum="6EC9446BFA157D14" modified="2009-10-13" version="1">MAREYIPPRLDQPRGRRQVSLKPSFDPDAFGRVSETIARFFGTARYLFIQSLIVVIWIALNILVVTKAIRWDPYPFILLNLAFSTQAAYAAPLILLAQNRQAERDKVQIAEDKAREELSFATMEYLTREIASLRMAVGEVATRDYVRGELQSLLKELDERGRDYSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV5</accession>
    <name>C7QHV5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_2211</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2211"/>
    <dbReference type="EnsemblBacteria" id="ACU71130">
        <property type="protein sequence ID" value="ACU71130"/>
        <property type="gene ID" value="Caci_2211"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2211"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012042_1_1_11"/>
    <dbReference type="OMA" id="EHANTRV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="679"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="770"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="883"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="11">
        <location>
            <begin position="30"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="11">
        <location>
            <begin position="255"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="333"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="106"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="372"/>
            <end position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU71130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="910" mass="96348" checksum="98376D062CAF50E3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI26</accession>
    <name>C7QI26_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4207"/>
    <dbReference type="EnsemblBacteria" id="ACU73071">
        <property type="protein sequence ID" value="ACU73071"/>
        <property type="gene ID" value="Caci_4207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4207"/>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022291">
        <property type="entry name" value="Bacteriocin_synth_cyclodeHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027624">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03882">
        <property type="entry name" value="cyclo_dehyd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03604">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="2">
        <location>
            <begin position="254"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="628" mass="68239" checksum="357FDAA02E1E6B36" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI97</accession>
    <name>C7QI97_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ordered locus">Caci_6119</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794703.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6119"/>
    <dbReference type="EnsemblBacteria" id="ACU74974">
        <property type="protein sequence ID" value="ACU74974"/>
        <property type="gene ID" value="Caci_6119"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6119"/>
    <dbReference type="eggNOG" id="COG0771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032540_0_0_11"/>
    <dbReference type="OMA" id="CNFENYL"/>
    <dbReference type="OrthoDB" id="1093223at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="128"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="341"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="130"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="51020" checksum="FB53B901ED84CEE1" modified="2009-10-13" version="1">MNQFAASGPVEFDGAVVTVVGARVVGLSASAALLARGARVTLIDRYDDAATAGRAAGAAAQGAVVRLGDDATLPEGTELLVVTPGLPPSAPIVAAARAAGVPIWGDAELAWRLRAPLADGSYAPWLVVTGTNGKSTTVRMAEAMLKQAGKGVAACGNIGYPVLDAVLRGQAGGEAGEPFEVLVIELSSYQLYWSSTLSPLASAVLNIAPDHIDWHGSYADYVAAKGRAYENCQVAAVYNAADLETVRLVEEADVVEGCRAIGFTLGAPGLSMLGVVDGILADRAFIADRRTNAAELGTVYDVEPNAPHNIANALAAAALVRAYGVEPAAVRDGLREFRPEPHRIAWVATIDGVDFVDDSKATNPHAASASIGAYDHVVWLAGGLAKGADFDDLVERHAKRLRGAVLFGAERHLVAEALRRRAPEVPVVDLGGPGPEQAAEVIAEAIAAARTMAVSGDTVLLAPACASMDMFTSYGQRGDVFAEAVKAAKAEATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC6</accession>
    <name>C7QIC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6149</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794732.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6149"/>
    <dbReference type="EnsemblBacteria" id="ACU75003">
        <property type="protein sequence ID" value="ACU75003"/>
        <property type="gene ID" value="Caci_6149"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6149"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="LMEEVFQ"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="35353" checksum="B8D707B73F3A0DDD" modified="2009-10-13" version="1">MTDVISLTGLVKTFGRRTAATRALDGLDLAVAPGEVHGLLGPNGAGKSTTLRILLSLLRPDSGEVRLFGRDAWKDAVALHRRLAYVPGDVALWPDLSGGQVLAMLAKLRGRTTDAKRMADLLERFDLDPGKKGRAYSKGNRQKVMLVAAFASETELLVLDEPTSGLDPLMEAEFRTCLAEEKARGRTVLLSSHILSEVEEVCDRVSIVRRGRVAESGTLTELRHLTRTLVSAELGRIPGAFDGFAGLHEVRVTELESGEGEGKGEGGGGVRLECTVDTEQLSALMVMLGTEGIRSLTTRPPTLEELFLRHYADPGRGRAEYQDAPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIC7</accession>
    <name>C7QIC7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794733.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6150"/>
    <dbReference type="EnsemblBacteria" id="ACU75004">
        <property type="protein sequence ID" value="ACU75004"/>
        <property type="gene ID" value="Caci_6150"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6150"/>
    <dbReference type="eggNOG" id="COG0372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025068_2_1_11"/>
    <dbReference type="OMA" id="LTYCGYD"/>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="42501" checksum="2D5A8C8AA7095930" modified="2009-10-13" version="1">MLESEQPRPTRSVTTVEVPRGLAGVIVTDTKVGDVRGEEGFYHYRQYNAVELAEKRTLEDVWVLMIDGYLPDAEQRAAFIAETTPLRHVPDKVKALLPAIAEAVHGEPMNGLRAALPLLAGQRGMRPLYDIDEQTRRADALFVSALAPTILTAVHRLGKGLEMVEPRDDLSYAANYLYMLTGSEPTAEQARAIEQYLISTVDHGFNNSTFTARVIASTGADLAAAVTGALGSLSGPLHGGAPSRALDTLDEIGTPDKAEDWVREQVEAGSRIMGFGHPVYRTDDPRSIMLRGVAQRLGGDLVDFAVAVEEHVLKALAELKPGRQLYTNVEFYAGVVMELSGVPRDMFTPTFATSRVIGWCANILEQAQDSKIIRPAAHYSGVSAPQPLPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QID0</accession>
    <name>C7QID0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6153"/>
    <dbReference type="EnsemblBacteria" id="ACU75007">
        <property type="protein sequence ID" value="ACU75007"/>
        <property type="gene ID" value="Caci_6153"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6153"/>
    <dbReference type="eggNOG" id="COG3185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012617_2_1_11"/>
    <dbReference type="OMA" id="MVSAHAY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="594" mass="63661" checksum="1091DF95A088CA37" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM6</accession>
    <name>C7QIM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796651.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76926">
        <property type="protein sequence ID" value="ACU76926"/>
        <property type="gene ID" value="Caci_8103"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8103"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_11"/>
    <dbReference type="OMA" id="LRIACEP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24677" checksum="DC0211B66179EEF3" modified="2009-10-13" version="1">MTATATTATADEPQGNPRKRRAILDAAGTVFLREGFTRASIDAIAAEAKVSKQTVYNHFGDKERLFMAMTDDVQDRTVAHVVELMDRDFPDASKLTGPEDLRAALLQLTGAWVRVVYTGPLVDLRKLVDAESEHHPDLQQRWFTNGPGRTMPRLNKLLSALARAGLLDVPAEVLAVPELLAHQLTTTAGSDVRRIAHEADFDAEFDRRIAQGVDFFLRAYAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ0</accession>
    <name>C7QIZ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796765.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8217"/>
    <dbReference type="EnsemblBacteria" id="ACU77040">
        <property type="protein sequence ID" value="ACU77040"/>
        <property type="gene ID" value="Caci_8217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8217"/>
    <dbReference type="eggNOG" id="COG0704">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078518_1_0_11"/>
    <dbReference type="OMA" id="WKHGIET"/>
    <dbReference type="OrthoDB" id="1648549at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="121"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="23914" checksum="80338C24C16159D1" modified="2009-10-13" version="1">MRDAFHEELDAISETLVEMTRLVGSAMARATTALLDADLTLAESVIDADDQVDDLQHSLDDSSFDLLARQQPVAGDLRTIITSLRMSADLERMGDLARHVAKVARRRYPQSAIPPEIRGTIVEMGDIAAELVAKVGSIIAARDVEAALALEAEDDEMDRLHRSLFKSLMDDKWKHGIETAVDVTLCGRYYERYADHAVSVAKRLVFLVTGEHPTPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJF2</accession>
    <name>C7QJF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="C7QJF2"/>
    <dbReference type="STRING" id="479433.Caci_2257"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71175">
        <property type="protein sequence ID" value="ACU71175"/>
        <property type="gene ID" value="Caci_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2257"/>
    <dbReference type="eggNOG" id="COG3934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059722_0_0_11"/>
    <dbReference type="OMA" id="HSWVFNG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="48923" checksum="8D7D807B1D2C31A6" modified="2009-10-13" version="1">MVQSTMVQTTMVQSTMVQSTMVQSTASQPPQSPPSTPRFGVNYTPSSGWFHHWLDFDLDAVRADLDSIAALGMDHVRVFPLWPVFQPNRTLIRPAAVEQLVAVADAAGERGLDVNVDGLQGHLSSFDFQPAWIHSWHRRNMFTDPDVVGAEAEYLRTLASALADRPNFIGMTLGNETNQFSGDPHPDPDRITPAQAAAWLDRLLEACEQGAPGKFHLHCSYDAAWYLDDHPFTPAHAARYGAATAIHSWVFNGTQQRYGTDSAAVAHHAEYMIELSKAWSADPRRPVWLQEVGAPQPHVPADKAADFTRATVANALDCPDLWGITWWCSHDVSKDLADFPELEYSLGLLTNDREPKPAGLELAKIVGEIRGQWAPPAPRSVGLVLDLPEEVTARATCGPGGGFYEAFMHLLEEGARPTAVLAGLAGDKNHLTARGITEVLAVEDVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJH8</accession>
    <name>C7QJH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786494.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2283"/>
    <dbReference type="EnsemblBacteria" id="ACU71201">
        <property type="protein sequence ID" value="ACU71201"/>
        <property type="gene ID" value="Caci_2283"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2283"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_808203_0_0_11"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="14"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37182" checksum="590F4244B0AC6A73" modified="2009-10-13" version="1">MPSPLHEYPRGPRLSLREFRPDDLLAWQRIAGDPRVAAHTPWPALATPDTTGAWLSETARMAQLQPRRSFYLAVEQYGDLIGSATLDILSFPHRQGEIGVYLRPDRWAEGLGTEASRLLLELAFSRLELHRVQTTVDPRNTPGMRVAEHVKMRPEGVLLDRFFVAGHWQDRAMYAITMPEWRGGGRGGAHAATAPAEAEIVDAEIVETETVSAVSAVSAVSAVSAETAETAETVEAGEAEPTDTFDAFSKPITADTPSAPTAVSFEGGPEEPLLGAPVPPPSEKQQPDAGQEPQEPLVGETSTSGAAFTDEDPDEDEVSEPRLLTAQIVMEQIEVVRIVPQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR3</accession>
    <name>C7QKR3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excision promoter, Xis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796887.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8339"/>
    <dbReference type="EnsemblBacteria" id="ACU77162">
        <property type="protein sequence ID" value="ACU77162"/>
        <property type="gene ID" value="Caci_8339"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8339"/>
    <dbReference type="eggNOG" id="COG3311">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140176_4_0_11"/>
    <dbReference type="OMA" id="RYRWVMA"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="8178" checksum="2614DC68FF04C112" modified="2009-10-13" version="1">MHGSARTGGDAARLSEVKFLTVAEVAQVMRVSKMTVYRLVHSGELPAVRVGRSFRVPEQAVQEYLRDAYVADTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB9</accession>
    <name>C7PVB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TROVE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0322</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ro 60 kDa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784570.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0322"/>
    <dbReference type="EnsemblBacteria" id="ACU69275">
        <property type="protein sequence ID" value="ACU69275"/>
        <property type="gene ID" value="Caci_0322"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0322"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_514729_0_0_11"/>
    <dbReference type="OMA" id="GHMKDMP"/>
    <dbReference type="OrthoDB" id="912523at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040322">
        <property type="entry name" value="TROVE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008858">
        <property type="entry name" value="TROVE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037214">
        <property type="entry name" value="TROVE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14202">
        <property type="entry name" value="PTHR14202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05731">
        <property type="entry name" value="TROVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140864">
        <property type="entry name" value="SSF140864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50988">
        <property type="entry name" value="TROVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="TROVE" evidence="4">
        <location>
            <begin position="12"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="523" mass="56619" checksum="E895FF8FF26D4784" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVF2</accession>
    <name>C7PVF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784603.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69308">
        <property type="protein sequence ID" value="ACU69308"/>
        <property type="gene ID" value="Caci_0355"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0355"/>
    <dbReference type="eggNOG" id="ENOG502ZSTS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1238361_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="22856" checksum="E0B6DFABE01C9C4C" modified="2009-10-13" version="1">MSTAAETAGSKPINYRLNLGEGWTRIRLDDHAEADVNAFLDTVFAAVPADAAEAGRDLIGGRLTTQIVAGRAKGGIDFYIPTPGGGPVPALTVMASEVKIPSAAVPEPADVVARVAASNPTARTGVIAGMPAVRIDRSAGAGLDAEPAGEDAEEDKDGFQPPRPRHIEYVVPVAGDPDHRWLSIALTGQAGPGGDEAKVDAAISRFDQAVADLAWTEGEGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW81</accession>
    <name>C7PW81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4466"/>
    <dbReference type="EnsemblBacteria" id="ACU73329">
        <property type="protein sequence ID" value="ACU73329"/>
        <property type="gene ID" value="Caci_4466"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4466"/>
    <dbReference type="HOGENOM" id="CLU_2552080_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="8594" checksum="B6F41954C5698822" modified="2009-10-13" version="1">MEIREAAIAAMGRTEVEELIDRAVRPDVPLRVLFAALDRYTELLRPVLDDEPAPGAGPAAAPLVLPVAPGPPRPAGPPGPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD9</accession>
    <name>C7PWD9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase U61 LD-carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793116.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4524"/>
    <dbReference type="MEROPS" id="S66.001"/>
    <dbReference type="EnsemblBacteria" id="ACU73387">
        <property type="protein sequence ID" value="ACU73387"/>
        <property type="gene ID" value="Caci_4524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4524"/>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_3_1_11"/>
    <dbReference type="OrthoDB" id="952832at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="16"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="180"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="32323" checksum="56ADA82BDABFB35B" modified="2009-10-13" version="1">MRSPLAPPALKPGDRVAVVALSGPPGRQELDLGLAALRSVGLLPEVFASARSVGPYPYLAADDKVRAADLARALGEPGYAAVICARGGYGVQRALELLDWDAVGAPEPRVVVGFSDVTALIEAVRSRLGWASVYGPMVSSVMFRSGVPSFEGLARLLLQPQKCTELAFADTRVLVPGVAEGVTVGGTASLLATSLATPFSVPARDGILFLEDVGELPYRLDRVLTQLRRTGYLDGVRGILCGTWDDCGPLADVEQLLEDRLGDLGVPVLLGADIGHGVFMQSLPLGVRARLDTAAATLTFLDPPLTSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW6</accession>
    <name>C7PWW6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796948.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8400"/>
    <dbReference type="EnsemblBacteria" id="ACU77223">
        <property type="protein sequence ID" value="ACU77223"/>
        <property type="gene ID" value="Caci_8400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8400"/>
    <dbReference type="eggNOG" id="COG0470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006229_4_1_11"/>
    <dbReference type="OMA" id="GFCDGCH"/>
    <dbReference type="OrthoDB" id="1971388at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004622">
        <property type="entry name" value="DNA_pol_HolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00678">
        <property type="entry name" value="holB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="1 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="41863" checksum="E394580544FECB83" modified="2009-10-13" version="1">MSGDSAAFQPYGVWTDLVGQDHISTDLVQAALGNGMTHAWLLTGPPGSGRSTAARAFAAALQCTTAGEPGCGYCLGCRTVLDGTHPDVLQLATDQLSIGVADTRGLVRRSSMTPSSGRWQVLLIEDADRLTEAAGNVLLKAVEEPSPRTIWILCAPGRDDMLPTIRSRCRHLLLRTPPSSAVAEILVRRDGVDPIRAREAARAAQGHIGRAKRLATDDEARAKRKAVLALASSLTDIGSALSAAQKLVDATIAEAKHDADERNVIETADMRLALGYQEGSRKAVPGAAGALKDLESRQKKRATRMQRDALDLALVDLAAFYRDVLAVQLGAIGGPGGDVTEPIHDDQYAAVRKIAAAGTPEATLRRIEAVLACRKAVERNVAPLLAVEAMAVNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWX0</accession>
    <name>C7PWX0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796952.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8404"/>
    <dbReference type="EnsemblBacteria" id="ACU77227">
        <property type="protein sequence ID" value="ACU77227"/>
        <property type="gene ID" value="Caci_8404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8404"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_2_1_11"/>
    <dbReference type="OMA" id="TKPAHQP"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="12829" checksum="F45A9EAE2296E06D" modified="2009-10-13" version="1">MNAPLTLTTIMFDCADPVALATFYSNATGWPVTDTDETFVYVGEGPITLAFQHVPDYRPPAWPDPAKHAHLDFQTPDKPQAIQHLLAAGAKLPDFQPGADRWTVLTDPEGHPFCVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXE0</accession>
    <name>C7PXE0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Selenocysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0553"/>
    <dbReference type="EnsemblBacteria" id="ACU69491">
        <property type="protein sequence ID" value="ACU69491"/>
        <property type="gene ID" value="Caci_0553"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0553"/>
    <dbReference type="eggNOG" id="COG1921">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2297588_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11052" checksum="264AB9FB2FB67B4B" modified="2009-10-13" version="1">MSDVRRDIPRTDVVLADPRLAAARARLGVDAVKAAVRGAQQKARDGEIAAEAVVEVAVASLPSSATTLRPILNATGVVLHTNLGRAPLAPAAVEACDGQKLGHQADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ0</accession>
    <name>C7PXZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73450">
        <property type="protein sequence ID" value="ACU73450"/>
        <property type="gene ID" value="Caci_4588"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4588"/>
    <dbReference type="eggNOG" id="COG3878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056726_1_0_11"/>
    <dbReference type="OMA" id="LYWLIRP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="31939" checksum="3A39CA17CD245ED0" modified="2009-10-13" version="1">MEISESPLAEAGRRFFSPENAKKWIELLRPGFHLRLQNDGEPLVGYLGGDPLLPADVEWPVWEGHGPLSFVAALDCGEIPVSELDIPVPDSGMLSFFYFNGVGEDAVQYLDPDSIKGGTRVIYVPEDAEGVASRPAPEGLEAFPRVMLTGELIATAPDNENAALVAAFGEGEDPAADDDYTEYPTVGDADGDGFYDALTTFGRDHSPHHRVGGYALPKAGSVTKEVTHVLAPGGDDTAKAARKALLPELVMLMQVDSDARAAMEWGDTGRLYWLIRRDDLAARDFAKATFTWQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY12</accession>
    <name>C7PY12_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4611"/>
    <dbReference type="EnsemblBacteria" id="ACU73472">
        <property type="protein sequence ID" value="ACU73472"/>
        <property type="gene ID" value="Caci_4611"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4611"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096760_0_0_11"/>
    <dbReference type="OMA" id="PRVCMRR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19282" checksum="8EEFDEBFE0E49CC6" modified="2009-10-13" version="1">MTDERLFPIRPASAEDYAGLAALELAADAVFEQFGIWPLPQTQPLPLPHTPDFTDAAAVLVAGRPPVGFARLDLVGAVPHIEQLSVHPAFVRRGLGTALVQACCDWAVSNHHSALTLTTFADVPFNAPFYARLGFTVIDPAALPEPLAALRRHEAEIGLDALGPRVAMRCALPASGPRHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY20</accession>
    <name>C7PY20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793209.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4619"/>
    <dbReference type="EnsemblBacteria" id="ACU73480">
        <property type="protein sequence ID" value="ACU73480"/>
        <property type="gene ID" value="Caci_4619"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4619"/>
    <dbReference type="HOGENOM" id="CLU_172312_0_1_11"/>
    <dbReference type="OrthoDB" id="2056482at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="11021" checksum="768EC67E4B48CC19" modified="2009-10-13" version="1">MANHIAINTGTLRDIGTQLGRLRDEFSHSTDITGAAAGEMGSGDVAGALNNFASDWSKKRDSLTQNLDTLSTTATQSAEHWDGLDADLAKSLINAFQQTQGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY71</accession>
    <name>C7PY71_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent helicase HrpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795090.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6512"/>
    <dbReference type="EnsemblBacteria" id="ACU75361">
        <property type="protein sequence ID" value="ACU75361"/>
        <property type="gene ID" value="Caci_6512"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6512"/>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_6_11"/>
    <dbReference type="OMA" id="DLRILVM"/>
    <dbReference type="OrthoDB" id="604268at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010225">
        <property type="entry name" value="HrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013689">
        <property type="entry name" value="RNA_helicase_ATP-dep_HrpB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08482">
        <property type="entry name" value="HrpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005496">
        <property type="entry name" value="ATP_hel_hrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01970">
        <property type="entry name" value="DEAH_box_HrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="223"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="862" mass="91789" checksum="ED26B6EF9F095AB8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYT9</accession>
    <name>C7PYT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Response regulator receiver and SARP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797136.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8592"/>
    <dbReference type="EnsemblBacteria" id="ACU77411">
        <property type="protein sequence ID" value="ACU77411"/>
        <property type="gene ID" value="Caci_8592"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8592"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_473871_0_0_11"/>
    <dbReference type="OMA" id="IHARRND"/>
    <dbReference type="OrthoDB" id="656640at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="421"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="575" mass="62930" checksum="C10B3AFF7BFE3300" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYV0</accession>
    <name>C7PYV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0569"/>
    <dbReference type="EnsemblBacteria" id="ACU69506">
        <property type="protein sequence ID" value="ACU69506"/>
        <property type="gene ID" value="Caci_0569"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0569"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_8_5_11"/>
    <dbReference type="OMA" id="MNRIGRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023934">
        <property type="entry name" value="LLM_FMN-dep_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04036">
        <property type="entry name" value="LLM_CE1758_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="374" mass="41483" checksum="0A816B71B61DBB35" modified="2009-10-13" version="1">MSQMQFGVFTVGDVTPDPTTGRAPTEHERIKAMVTIAEHAEQAGLDVFATGEHHNPPFVPSSPTTLLGWIAGRTSKLLLSTATTLITTNDPVKIAEDYAMLQHLADGRVDLTLGRGNTGPVYPWFGKDIRDGIDLALENYALLRRLWDEDVVDWSGRFRTPLQNFTAAPRPLDGVAPFVWHGSIRSPEIAEQAAYYGDGFFHNNIFWPKEHTQRMVALYRRRFAHYGHGTEEQAIVGLGGQVFMRKNSQDAVREFRPYFDNAPVYGHGPSLEEFTAETPLTVGSPEQVVERTLSFRAYAGDYQRQLFLLDHAGLPLKTVLEQIDLLGAEVVPVLRKEFAIGRPAGVPDAPTHASLTARHDERSALSDTKEAIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYY8</accession>
    <name>C7PYY8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0608</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784839.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0608"/>
    <dbReference type="EnsemblBacteria" id="ACU69544">
        <property type="protein sequence ID" value="ACU69544"/>
        <property type="gene ID" value="Caci_0608"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0608"/>
    <dbReference type="eggNOG" id="ENOG5032SPK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126433_0_1_11"/>
    <dbReference type="OMA" id="ANANLAW"/>
    <dbReference type="OrthoDB" id="2018019at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13487" checksum="4F679B97114E8D79" modified="2009-10-13" version="1" precursor="true">MNAFLWVVQALLAALFLLSGSLKSTWPKDRLIASGQTGVTPFPLPLLRFAAVCELFAAAGLILPRAAGIAPVLTPIAAVGLCCVMAGAISSHCYLLRRDVAAGRGRREAVNVVATTVILGMCVLVAVGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ34</accession>
    <name>C7PZ34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784885.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69590">
        <property type="protein sequence ID" value="ACU69590"/>
        <property type="gene ID" value="Caci_0654"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0654"/>
    <dbReference type="eggNOG" id="COG1801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046519_2_1_11"/>
    <dbReference type="OMA" id="HDDFRFC"/>
    <dbReference type="OrthoDB" id="1068600at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="32463" checksum="FB83139618A0FD95" modified="2009-10-13" version="1">MKLHVGCAMWTLARWQGRLLPHPLPPRERLAAYATWCNAVEGNTTFYATPSRATVEMWAAQAPEDFRFLLKLPKPVTHERRLAPEVFAPDGALHSFFTAIEPLGRHAALWIQLPASFGPTDLPTLAAFLSRVPKGYRYAVEVRHPAFFDGSRGERDLEALLTEADAEWVPFDTTVLYETPPTTDAEREAWSKKPRLPRRTRALTRFPVVRYIGRDDAELTAQGWQPWADITAQWLREGRSPTVFIHTPDNADAPVLARRFHEDVRRRVPEVEALAEPMPVGPPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ55</accession>
    <name>C7PZ55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784906.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0675"/>
    <dbReference type="EnsemblBacteria" id="ACU69611">
        <property type="protein sequence ID" value="ACU69611"/>
        <property type="gene ID" value="Caci_0675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0675"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="YAEHPRT"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="30952" checksum="0005EDADD44D51D0" modified="2009-10-13" version="1">MNAVVVEDLTMRYRGHTALDGVDLTLAPDTIHGLLGRNGAGKTTLMRILTGQEFETSGRVEVFGQPPRENPAVLNRVCFIREAQKYPQNFKVREAFAAAAIACPGWDQAYADRLVQDFDLPLKRQIKKLSRGQLSAVGIIIGLAARAPLTLFDEPYLGLDAVARHVFYDRLLEDFSENPRTVILSTHLIDEVADLVEHVVLIDHGTVLMDADADGLRGRAVSVSGPAEAVAAYVEDAPVLHRSGLGGQLRVALAERPERPAEGVSVDSLSLQELIVLTTNQGDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZG2</accession>
    <name>C7PZG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein Hsp20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786912.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2704"/>
    <dbReference type="EnsemblBacteria" id="ACU71619">
        <property type="protein sequence ID" value="ACU71619"/>
        <property type="gene ID" value="Caci_2704"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2704"/>
    <dbReference type="eggNOG" id="COG0071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_9_0_11"/>
    <dbReference type="OMA" id="PMPLDAY"/>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="26"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15964" checksum="07A0329A43267A69" modified="2009-10-13" version="1">MLMRTDPFRDLDRIASQLLGTTAAGTWTRPNPMPLDAWREGDEFVVCFDLPGVSLDAIDIDIERNVLTVKAERRPAALGEAKVEISERPLGAFSRQLFLGDTLDTDNIKAGYDAGVLTLRIPVAEKAKPRKVQITTADEKKAINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS0</accession>
    <name>C7PZS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4724</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793314.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4724"/>
    <dbReference type="EnsemblBacteria" id="ACU73585">
        <property type="protein sequence ID" value="ACU73585"/>
        <property type="gene ID" value="Caci_4724"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4724"/>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017959_8_2_11"/>
    <dbReference type="OMA" id="RKSAPFF"/>
    <dbReference type="OrthoDB" id="1419334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017588">
        <property type="entry name" value="UacT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03173">
        <property type="entry name" value="pbuX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01116">
        <property type="entry name" value="XANTH_URACIL_PERMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="53290" checksum="34C03B8389A30C2A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZU8</accession>
    <name>C7PZU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793342.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4752"/>
    <dbReference type="EnsemblBacteria" id="ACU73613">
        <property type="protein sequence ID" value="ACU73613"/>
        <property type="gene ID" value="Caci_4752"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4752"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_17_1_11"/>
    <dbReference type="OMA" id="GLSEMCF"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="427" mass="43158" checksum="CF172E579EC632DC" modified="2009-10-13" version="1">MNGSVLRWVCAYTCSVSGDSVYFVTLSWAASRSLGPVAAGVVLAVGAVPRALLMLGGGVVADRFGPWRVLIGSDLVRCVLVVGAALAVADRVQLGVLVALAVGFGTVDALFMPAVGALPPVLVAPDELARVQGMRVLGVRAANLAGPVLAGVMLGVGGASGSFLGAAALFGASLVLLMTLRIPRTAVAPEAGLSLWEQFGEGLRYVRQHTELRRLVIVIGLSEMCFSGPIAVAVVLLVAERHWSSTTAGWILGAFSVGGAAVAGIMATTFAHRASDSGSVSDTGSASRARLTLTASLALTAALLLAWTTLGRAGAIAISACLGATTGVTTVVANARLQTAAAPQFLGRVTSVTTLCTLGLSPLLFPLVGVAAEAWGTGAFFALCAVVCAAAAVVSSRSTPSGRLTAARADALPTPARPRTPPRSPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZV4</accession>
    <name>C7PZV4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4758"/>
    <dbReference type="EnsemblBacteria" id="ACU73619">
        <property type="protein sequence ID" value="ACU73619"/>
        <property type="gene ID" value="Caci_4758"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4758"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_11"/>
    <dbReference type="OMA" id="YWANDSV"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05324">
        <property type="entry name" value="carb_red_PTCR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045313">
        <property type="entry name" value="CBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="23886" checksum="7BBF98B778528389" modified="2009-10-13" version="1">MIALVTGANRGLGRETARQLVAAGHRVLIGARQEAAARDTAAELGERAYPVRLDVTSTEDIAAAVEEVREHFGHLDVLVNNAAIHYDTWQHAIGADLMVVREAAETNVYGPWQLVQAMLPLLRAGSHQRIVNVSSGAGSLTEMTSGSTPAYSITKAALNALTRMLAADLRGDGILVNAVCPGWVATDMGGPGGRPVREGAAGIVWAATLPDGGPSGGFFRDRKAIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q013</accession>
    <name>C7Q013_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75506">
        <property type="protein sequence ID" value="ACU75506"/>
        <property type="gene ID" value="Caci_6660"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6660"/>
    <dbReference type="HOGENOM" id="CLU_803373_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982381" evidence="1">
        <location>
            <begin position="36"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="34419" checksum="5EF10E5D389A4F02" modified="2009-10-13" version="1" precursor="true">MNTEIGDATARRKAVSAVVAFGVAVAAVAVTAACASGMSGKSAGKLDPSLPADQVMHAAAQSVLAADGVHVHGTVTVTGGAGAGGGAAGDSTVVIDGPVRFGPKMVADLSLAVKPDSDDVPDRVIYDGSTLYAKAPPNLHAKVVAKPNATWFAIPSDDHELFGVHLPVKLGDPAGLVSGLLAEGKFARVGAETADGVATVRYAAEFAGGKPAHVDVWLNHSGLPVELRVKAGNSLGDLHFTDWGKPVKITAPKADEVMNPTDQVSFSMSASGFTVTVGSGLLDGSSFSSSGVYEVPPGPSSSTCIAVTFTPSAPSGASATTADACIDIGSLTFQTLSAPPTATGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q027</accession>
    <name>C7Q027_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6674</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795249.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6674"/>
    <dbReference type="EnsemblBacteria" id="ACU75520">
        <property type="protein sequence ID" value="ACU75520"/>
        <property type="gene ID" value="Caci_6674"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6674"/>
    <dbReference type="eggNOG" id="ENOG502ZGDZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2697840_0_0_11"/>
    <dbReference type="OMA" id="HFVEIRI"/>
    <dbReference type="OrthoDB" id="2022373at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="8402" checksum="8749EE733B2A0D1C" modified="2009-10-13" version="1">MFSLRRSHRNEAWEGMVVDKKRGMTDGSSMYFYLKVRVSDGSTKRVRVHRDLWKTLEDGDTVVKAAGAEPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q060</accession>
    <name>C7Q060_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6707"/>
    <dbReference type="EnsemblBacteria" id="ACU75553">
        <property type="protein sequence ID" value="ACU75553"/>
        <property type="gene ID" value="Caci_6707"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6707"/>
    <dbReference type="eggNOG" id="ENOG5033CJI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168827_0_0_11"/>
    <dbReference type="OMA" id="TDIFQAG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="11679" checksum="F808DBC21E1786B5" modified="2009-10-13" version="1">MSDGGTVKVTAEAHLHIGQLLNLLQGPLGDVLSQITSHGLALTDPAVWEGPAASMFSSTIWPAAQSQLDSVRGTLMELQQQVGGILSNVTSAGSGLPVVGQLPVVGGLVGGLTQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q079</accession>
    <name>C7Q079_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6726"/>
    <dbReference type="EnsemblBacteria" id="ACU75572">
        <property type="protein sequence ID" value="ACU75572"/>
        <property type="gene ID" value="Caci_6726"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6726"/>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013864_0_0_11"/>
    <dbReference type="OMA" id="NWIEPRC"/>
    <dbReference type="OrthoDB" id="1177619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_helix" evidence="1">
        <location>
            <begin position="304"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="61967" checksum="DC4A8878CDE71E1C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0A8</accession>
    <name>C7Q0A8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797165.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77441">
        <property type="protein sequence ID" value="ACU77441"/>
        <property type="gene ID" value="Caci_8625"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8625"/>
    <dbReference type="eggNOG" id="ENOG5033MUP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1488029_0_0_11"/>
    <dbReference type="OMA" id="LIRELPM"/>
    <dbReference type="OrthoDB" id="1964640at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19565" checksum="54E975193499324D" modified="2009-10-13" version="1">MTDLDRLASLTATELSSLLTASESAPVDKHGGDWLAIVQLLTARLTEEGGTLTAEELNLGATALDVALDSAEQAGVIDRNEAAIRRLNLMSVLLRLRGPNPDVALLNPQRMYGLFSTAVPLSAAQIREVPPNWRALDVDTIRRLRLVKNLVVPLLGVKSILEQAGFADNLAVWEDALPRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0K3</accession>
    <name>C7Q0K3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0696"/>
    <dbReference type="EnsemblBacteria" id="ACU69631">
        <property type="protein sequence ID" value="ACU69631"/>
        <property type="gene ID" value="Caci_0696"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0696"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064093_1_0_11"/>
    <dbReference type="OMA" id="HAIGHAD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="40293" checksum="E3691037C7486D26" modified="2009-10-13" version="1" precursor="true">MTSSIPSVAIAAVAAASVIRGLSSRYGAQRSRRAAGRTGQSGQTGRAGRGAQAEAVRPVPIDRSHGDPELAALRQAARVADWPAMEAILRPVRERADFERLTFLIGNVEDLGGDFLLKLPEQLPGDPLVLSVAGARHSAWAWEARTGYRASQVSEEQFKVFHERLRIAEEYLYTAVELDPDSAAPWYTLCVTSRGLEHGAEITRRRFEAGIRRAPGHVGLHRQMLQQLCAKWGGSHEQMHAFATGAFDAAPPGSGLGEVVAQAHLEHWLDLEQGPDDEYIRGTAVVQELRRAADTSVFHPAFAPTSSPYTALNAFAMAFWLADDKEAAGRLFERIGDHATKAPWRYRGDPERVFAVARQDCVKKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Q6</accession>
    <name>C7Q0Q6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0749"/>
    <dbReference type="EnsemblBacteria" id="ACU69684">
        <property type="protein sequence ID" value="ACU69684"/>
        <property type="gene ID" value="Caci_0749"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0749"/>
    <dbReference type="HOGENOM" id="CLU_2552078_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="9118" checksum="26C5208C339A7ABD" modified="2009-10-13" version="1">MDIASDSIERVTRSSGKVIYLTSYRGLTRARTVGGPTRVWHHALGTTLNAPTAHGETGNGAREAAVIKEWSRWSERLERPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V1</accession>
    <name>C7Q1V1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name evidence="5" type="ordered locus">Caci_6811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6811"/>
    <dbReference type="EnsemblBacteria" id="ACU75652">
        <property type="protein sequence ID" value="ACU75652"/>
        <property type="gene ID" value="Caci_6811"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6811"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_6_11"/>
    <dbReference type="OMA" id="CEIPDEQ"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="8716" checksum="908408AF97CCA4BC" modified="2009-10-13" version="1">MALTQEEILADLAEIVEEVAGVDAADVQMDKSFTGDLDVDSLTMVEVVVAAEEKFSVKIPDDAVKDLSTVGDAVGYIQKNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V6</accession>
    <name>C7Q1V6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795385.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6816"/>
    <dbReference type="EnsemblBacteria" id="ACU75657">
        <property type="protein sequence ID" value="ACU75657"/>
        <property type="gene ID" value="Caci_6816"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6816"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_0_0_11"/>
    <dbReference type="OMA" id="VLYERTP"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045981">
        <property type="entry name" value="DUF5937"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19361">
        <property type="entry name" value="DUF5937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5937" evidence="1">
        <location>
            <begin position="102"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="35338" checksum="E979F8F61D9DEE0F" modified="2009-10-13" version="1">MVISLGFGPADLARCRFAVSPAFETLSAIRDATGSQGPGAHARWLDSVRPALPGLGLDPIVLLQPRRGYTPDFLAPPPTAPVGDFDAELTRIAATPAPVVHREIELALRHTPGARDTPAGRLLLGDPAEVLSLLTQLIRGAWETLVAPHWPLVRAVLEADVAHQSRRLAEGGLDALFADLHPTVRWTGDTLIRDPGGDEHHDLDGRGLILMPSVFKWDEVIVITDAPWQPTLVYPARGLGNAFEARRGTPAAALTKLVGRTRAHLLTGLEEPVSTSRLAHRHALALGTVSEHLSVLRDAGMVVGERHRHEIRYRRTELGDRVVQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q215</accession>
    <name>C7Q215_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathionylspermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797276.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8737"/>
    <dbReference type="EnsemblBacteria" id="ACU77552">
        <property type="protein sequence ID" value="ACU77552"/>
        <property type="gene ID" value="Caci_8737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8737"/>
    <dbReference type="eggNOG" id="COG0754">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059175_0_0_11"/>
    <dbReference type="OMA" id="QWNSLHE"/>
    <dbReference type="OrthoDB" id="692145at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSP_synth" evidence="1">
        <location>
            <begin position="12"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="44154" checksum="DE04C0C3343B693A" modified="2009-10-13" version="1">MRRLQSPPREGWRQAVESQGLVFPVTDLEDGSVVPYWYESAHYSFTMAEVDALEDTTAELHAMCLAAAEHIVSRDRFADLGITDPAVVRAIRESWSAQPPSLYSRFDLRYDGDDGRAAKLLEYNADTPTMLLESAICQWYWLQDAHPELDQWNSLHERLVDAWQKMRLRLAGGPVHFVYAECDESGEDFMTSSYVAETAEQAGLVAVVLPVEKIGWHAASGWFVDLDQTRMRTVFKLYPWEWLVAEDFGPQALAAFDRTQWLEPIWKMLLSNKALLAILWELYPDHPNLLPAYLDGPRDLKDYVAKPLLGREGASIRIVTGGEHFEQPGHYGREGYVYQEFSALPSFPGSDGGGRAVLGSWLVGGEPAGLGIRESDGLVTDTYARFVPHVIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q226</accession>
    <name>C7Q226_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797287.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8748"/>
    <dbReference type="EnsemblBacteria" id="ACU77563">
        <property type="protein sequence ID" value="ACU77563"/>
        <property type="gene ID" value="Caci_8748"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8748"/>
    <dbReference type="eggNOG" id="COG1878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_0_0_11"/>
    <dbReference type="OMA" id="TGWWTRF"/>
    <dbReference type="OrthoDB" id="831439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="33603" checksum="5CC66750446C285B" modified="2009-10-13" version="1">MPLPDQFTDLARRVNNWGRWGPRDERGTLNLITPARLQHAATLIRTGRTIPLAIPLDENGPQIGMIEGRDNPKRTMIMVNAQVMGQEHAFCTSDDRVEMGLQACTHWDALAHVSYEGRLYNGFDASQITDAGATHCGIDKAGAIVGRGVLLDVARALGVSRLGDATRGHALTPADLDAAAEFGKVEIHPGDLVLIRTGAMTALKAGDKLAYSFPTSGPSLQTVPWFHTHDVAAVATDNVAFEVYPPERDDAQLPVHLLHLVEMGMLQGQNWDLEALAEDCAEDGVYEFFLSASPEPFTRAVGAPVIPVAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2D9</accession>
    <name>C7Q2D9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoH</name>
        <name evidence="7" type="ordered locus">Caci_0848</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785076.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0848"/>
    <dbReference type="EnsemblBacteria" id="ACU69781">
        <property type="protein sequence ID" value="ACU69781"/>
        <property type="gene ID" value="Caci_0848"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0848"/>
    <dbReference type="eggNOG" id="COG1005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_0_1_11"/>
    <dbReference type="OMA" id="MYVGMGI"/>
    <dbReference type="OrthoDB" id="1559067at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34807" checksum="9FA7D0E9C03E91A3" modified="2009-10-13" version="1">MTVTDAVVRLAIILGFFLVVPLVVGQMEHKAMAHMQSRVGPMYAGAFHGWAQLVADGVKFAQKEDVVPAAADRRVFQLAPAVALIPYLVVLVAIPIGPGTQVGRDLDAGLFFVLAVMGVGVLGSLMAGWASANKYSLLGGIRSAAQLMAYELPMILAASSVAMAAGTLSLTGIAVAWHWYWLPWQLMGLFVFFVSGLAELQRPPFDMPVADSEIIFGAYTEYTGIRFALFLLAEYAGIVVLSLLTTVLYLGGWKGPFYLGLGAAGFGWFWTLAKTLVLAFLVIWLRVSYPRLREDQLQKLAWTTLIPLALAQIALTGILKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P4</accession>
    <name>C7Q2P4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787079.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2877"/>
    <dbReference type="EnsemblBacteria" id="ACU71786">
        <property type="protein sequence ID" value="ACU71786"/>
        <property type="gene ID" value="Caci_2877"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2877"/>
    <dbReference type="HOGENOM" id="CLU_2913952_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="6340" checksum="2500962B8414F6DC" modified="2009-10-13" version="1">MPLSDHLEQLTNATATRDGDAGVEALEAIEAEYGPVVAAVITADLLAHVARQASERPAPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Q8</accession>
    <name>C7Q2Q8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787093.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2891"/>
    <dbReference type="EnsemblBacteria" id="ACU71800">
        <property type="protein sequence ID" value="ACU71800"/>
        <property type="gene ID" value="Caci_2891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2891"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_8_4_11"/>
    <dbReference type="OMA" id="MPYLTPR"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UTRA" evidence="1">
        <location>
            <begin position="27"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="18731" checksum="BCD9E4623804E312" modified="2009-10-13" version="1">MHENPDDSAAYLAARSGPDAWSAATADRGGASRILAVETVKPPQRIADALQLGAAERAVVRRRLMLIEDKPVEIANSWYPELLAHGTPLADPKKIKGGAPAVIAALGLALAYADEEVELESAPNAEEAQLLQVPPDKRVARLFRTAYTGDDTPVEVTDSLMLPAGRVLQYRIEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U4</accession>
    <name>C7Q2U4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23436"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:137796"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O = 5,6-diaminouracil + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:55020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:46252"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2927"/>
    <dbReference type="EnsemblBacteria" id="ACU71836">
        <property type="protein sequence ID" value="ACU71836"/>
        <property type="gene ID" value="Caci_2927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2927"/>
    <dbReference type="eggNOG" id="COG3236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084247_1_0_11"/>
    <dbReference type="OMA" id="QWKGANK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="SSF143990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="3">
        <location>
            <begin position="46"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="22234" checksum="5B2ABD85CBD689F0" modified="2009-10-13" version="1">MIGPERPNPTAARSRGELAAMIRAGAEPKWRLFFGHRARIPGVVDEACLSQWWPAEFRIGSITYFTAEHWMMVSKAQLFGDSDAWARVLSTRDPAVAKRAGRNACDFDETTWAAVRFGLVVAGNYAKFAQNSDLRAFLAGTAGEVLVEASPYDRVWGVGLAASHRDVRDPAAWPGLNLLGFALMRVREELMARPDHTEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q317</accession>
    <name>C7Q317_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3000"/>
    <dbReference type="EnsemblBacteria" id="ACU71909">
        <property type="protein sequence ID" value="ACU71909"/>
        <property type="gene ID" value="Caci_3000"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3000"/>
    <dbReference type="HOGENOM" id="CLU_3341850_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="37" mass="4125" checksum="64D99C7F9DCF4176" modified="2009-10-13" version="1">MSLRAIAAEARMTPEGVRKMLKRLDEQAKAEPNVPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q381</accession>
    <name>C7Q381_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4957</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4957"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH30">
        <property type="family name" value="Glycoside Hydrolase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73817">
        <property type="protein sequence ID" value="ACU73817"/>
        <property type="gene ID" value="Caci_4957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4957"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022864_1_0_11"/>
    <dbReference type="OMA" id="WNDGLIY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982848" evidence="4">
        <location>
            <begin position="42"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="580"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="688" mass="69438" checksum="3B63261840E5A579" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3A7</accession>
    <name>C7Q3A7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4983"/>
    <dbReference type="EnsemblBacteria" id="ACU73843">
        <property type="protein sequence ID" value="ACU73843"/>
        <property type="gene ID" value="Caci_4983"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4983"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029779_1_0_11"/>
    <dbReference type="OMA" id="WGGRWTG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="538" mass="58483" checksum="4A14B5BD8B42B234" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3L7</accession>
    <name>C7Q3L7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795510.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6951"/>
    <dbReference type="EnsemblBacteria" id="ACU75782">
        <property type="protein sequence ID" value="ACU75782"/>
        <property type="gene ID" value="Caci_6951"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6951"/>
    <dbReference type="eggNOG" id="ENOG5031V31">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_870567_0_0_11"/>
    <dbReference type="OrthoDB" id="1681528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36791" checksum="E1B0B19E32AED4CC" modified="2009-10-13" version="1">MIGEDFRESSAESEFLRAVGEGRMEEFLERDPSGGAILYRIVDDVVYEQLTRKIERRRGHLLCAASRSKLTAECHDRHQDNVEAVHADVLRHAGVQIANLCGWLVPRLTPVTVDAHRRRRGERGALQRPRLPAWLVVALDADPWLTELAREILVWVGVPLALNTGLWPLGAWADRRAEVLGRWGEAGELGVVPEVEQVLAAMRTRPSWYERYVETPLGRKQPPLVPAAWVGEDREPDHLELGRPELAADDLLDELAALAIDAVRARAAAGVELRTAVVEVLTGVFGGAGSLGTGSDRVADAEADFVARLLDDPAAVDRIAAVFLAIVEAPEDGSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3T4</accession>
    <name>C7Q3T4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797416.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8879"/>
    <dbReference type="ESTHER" id="catad-c7q3t4">
        <property type="family name" value="HNLyase_Bact"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77692">
        <property type="protein sequence ID" value="ACU77692"/>
        <property type="gene ID" value="Caci_8879"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8879"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046066_3_3_11"/>
    <dbReference type="OMA" id="YWHRVAP"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="25250" checksum="A9E0A105A734B566" modified="2009-10-13" version="1">MATYVLIHGASSDSWLWHRVVPLLRAAGHDVVAPDLPISDPASGIPEYADAVVAALGDRAAADDLIVVAQSLGSFTGTVLSQRVPAKLLVFVSGMAPKEGETPGEWWGATGYTEARQASDARLGLPEGADLKVVFFHDVPKDVVEEAFERGEVQQSERAFAPPPMPALPADLPVRYVVGRDDRFFPLDFQRRTIQERLGFAPDEMDGGHLLPLARPEELVERLENYRVEAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q402</accession>
    <name>C7Q402_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77760">
        <property type="protein sequence ID" value="ACU77760"/>
        <property type="gene ID" value="Caci_8947"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8947"/>
    <dbReference type="eggNOG" id="ENOG5033UH7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_751616_0_0_11"/>
    <dbReference type="OMA" id="SAIWTES"/>
    <dbReference type="OrthoDB" id="2090364at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="40719" checksum="695DB442FBCC4A9A" modified="2009-10-13" version="1">MSTLMDALDEPQALLLELVWSQFEKAAQFPNFNWVEYQMRAKGYDAAEVIGGLPSIGKPEVRGRYSAIWTESAGSFPQPGNRVCLTMAGLYHTKDRSKTGGIISGVLFFLRTLSEARAQIANHPFDVPDIRVSLSETLSEVSDQAYVASVGMVAEHEWLAMQVHRTEADWTGRLALLNRADFMQIEDYLTAITAVCTEQRTAILTNRNPRALARSITNFDLACELVLKRSLVKKPAISRTVLLGQDATSHTDLVDGISALGILLHELDVPKTRQDPPCGSKRLQPYLEAELPNIDKSRVESATALMDAVRIIRNSDQHPARVAELVSAYELLGLAFPVRDPTAAWDIIRAQMDAAFNTLQDEILAART</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q420</accession>
    <name>C7Q420_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797502.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8965"/>
    <dbReference type="EnsemblBacteria" id="ACU77778">
        <property type="protein sequence ID" value="ACU77778"/>
        <property type="gene ID" value="Caci_8965"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8965"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_18_0_11"/>
    <dbReference type="OMA" id="ARSWAMA"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23963" checksum="2776AA5100B9B6C4" modified="2009-10-13" version="1">MPLIVLWDIDHTLIDNAGVSKEIYASAFKALAGHPPAHPARTDGRTDRLIISDMFADHHLPVPAWDLAEAALEQAGTCHEQELKARGRVLPGVRSVLKEAYEDPAIVSSVLTGNIAANALVKLRPFGLDRYLDLAVGAYGADSDRRADLVVMARERIGRAYPWADRASTIVVGDTPRDVEAALTAGAQVIAVASGVHSAELLHAAGATVVLNDLRELRGHLHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q444</accession>
    <name>C7Q444_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glmM</name>
        <name evidence="13" type="ordered locus">Caci_0973</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785198.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0973"/>
    <dbReference type="EnsemblBacteria" id="ACU69904">
        <property type="protein sequence ID" value="ACU69904"/>
        <property type="gene ID" value="Caci_0973"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0973"/>
    <dbReference type="eggNOG" id="COG1109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016950_7_0_11"/>
    <dbReference type="OMA" id="PHNPEPL"/>
    <dbReference type="OrthoDB" id="1265792at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="3"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="159"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="258"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="374"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="46681" checksum="DE13A8D8105D39AE" modified="2009-10-13" version="1">MTRLFGTDGIRGMANRDLTAELALDLSVAAAHVLGEVGAFEGHRPRAVVGRDPRASGEFLEGAVVAGLASAGVDVLRLGVLPTPAVAYLTEFLGADLGVVLSASHNPAPDNGIKFLARGGVKLDDALEDAIEARMNEQWSRPVGAAVGRVADYPEGGERYIEHLLATLPNRLDGLKVVVDEANGAAFRVSPEALRRAGAEVIATHVEPDGLNINDDCGSTHLAKLKAAVIEHGAHAGIAHDGDADRCLAVDAAGEEVDGDQILAVLAISLRDQDKLAGQTVVGTVMANFGFKQAMQREGLTFVETAVGDRYVLEVMRAGGYVLGGEQSGHVILTEHATTGDGTLTALHLLARVAATGRSLADLASVMNKLPQVMINVKDVDKTRAATSAELAQAVKEAETELADTGRVLLRPSGTEPLVRVMVEAEDGELARRLAEHLAGVVKTALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q471</accession>
    <name>C7Q471_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1003"/>
    <dbReference type="EnsemblBacteria" id="ACU69931">
        <property type="protein sequence ID" value="ACU69931"/>
        <property type="gene ID" value="Caci_1003"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1003"/>
    <dbReference type="HOGENOM" id="CLU_189245_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10906" checksum="848FB4F091CE3C90" modified="2009-10-13" version="1">MSDSGGKNAKNQTLMWEVRCEPGKAAAVEEWIRAVIVPPLWDDEEVASYNAYSSVGQDGERVVVVIDYLAAAPATLSAEPPERLIARPPHAWVFQRLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q491</accession>
    <name>C7Q491_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1023"/>
    <dbReference type="EnsemblBacteria" id="ACU69951">
        <property type="protein sequence ID" value="ACU69951"/>
        <property type="gene ID" value="Caci_1023"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1023"/>
    <dbReference type="eggNOG" id="COG2050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_4_1_11"/>
    <dbReference type="OMA" id="NFAPWVL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="59"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16434" checksum="5A39C2B127DD3215" modified="2009-10-13" version="1">MNVTTPQPPAPLTQAQATEILAQNFAPWIQSLNLTVEETTPTTTTLRLPWHPTLARQGGTLCGQALMAAADTATVIAISAARGTYCPMTTVQQNTTFQRPIHQSDVLITAHITKLGRTLAFTDITMTPAPDPTHPQTPPPPPAAQATTIYALLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H8</accession>
    <name>C7Q4H8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endodeoxyribonuclease RusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787240.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3038"/>
    <dbReference type="EnsemblBacteria" id="ACU71947">
        <property type="protein sequence ID" value="ACU71947"/>
        <property type="gene ID" value="Caci_3038"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3038"/>
    <dbReference type="eggNOG" id="ENOG5033AQE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2012009_0_0_11"/>
    <dbReference type="OrthoDB" id="1770914at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036614">
        <property type="entry name" value="RusA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103084">
        <property type="entry name" value="SSF103084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14629" checksum="E36E0208C08B0111" modified="2009-10-13" version="1" precursor="true">MDTATADTEATTYVVALPAGMKLLNANDRVHWRTRARITKALREAAAKSARDAHIPPMEQIRIQAVLHPHDKRRRDPHNWYPSYKAAIDGIVDAGVIPDDDGKHLISIEVVLGAPVRHTQIALRITPFGVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q513</accession>
    <name>C7Q513_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ThuA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793690.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5101"/>
    <dbReference type="EnsemblBacteria" id="ACU73961">
        <property type="protein sequence ID" value="ACU73961"/>
        <property type="gene ID" value="Caci_5101"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5101"/>
    <dbReference type="eggNOG" id="COG3828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100195_0_0_11"/>
    <dbReference type="OMA" id="AGWHGGI"/>
    <dbReference type="OrthoDB" id="1452706at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA" evidence="1">
        <location>
            <begin position="11"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="24317" checksum="B466D6C53FFD9C51" modified="2009-10-13" version="1">MAGSDAAVPRRVVVVRGGWEGHAPVATTEVFVPGLVAAGFEVVVADDLDVYCDAELLAGTDLVVQCWSEGEDAAELSRKQSAGLVGAVAAGMGFAGWHGGVLAAFRDPDYLRMVGGLFLFHPPEFLTYRVRIAAEHAEHPIVAGLEDFDVHSEQYWVLGDGRNTVLATTVVESRDGGQGEGAVAMPVVWTRRWGAGKVFVSAVGHRVEDLRAPAVRVLTERGLLWAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5P9</accession>
    <name>C7Q5P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797584.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9047"/>
    <dbReference type="EnsemblBacteria" id="ACU77860">
        <property type="protein sequence ID" value="ACU77860"/>
        <property type="gene ID" value="Caci_9047"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9047"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_11"/>
    <dbReference type="OMA" id="MRLNFTY"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="56"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="47656" checksum="408946D7E29DB924" modified="2009-10-13" version="1">MELPQRPGSRLDSYVDRYAARTRGMTASEIRALFAVASRPEVVSLAGGMPNLAALPMDSIATVAEELVRESGTVAMQYGGAQGDETLREQICEIMRLEGIEGHPDDVIATVGSQQALDLVTRIFIDPGDVILAEGPSYVGALGVFASYQAQVVHVAMDDQGLVPDTLRTAIASVKASGRRIKFLYTIPNFHNPAGVTMAVERRPEIVEICRDAGILILEDNPYGLLGFQGEIYPALRSLDTENVIYLGSFSKTFAPGFRVGWALAPHAVREKLTLAAEAADLCPPAFSQMMVSRYLSTQPWREQIKAFRAMYLERRDATLTALSELMPAGVTWTKPDGGFYVWVTLPPGLDSKAMLPRAVTARVAYVPGTGFYSDGFGASSLRLSYCYPTPERIREGVRRFADVLREEMELRAAFGHEASRALESREGVDTPGPDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5R3</accession>
    <name>C7Q5R3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785304.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1084"/>
    <dbReference type="EnsemblBacteria" id="ACU70010">
        <property type="protein sequence ID" value="ACU70010"/>
        <property type="gene ID" value="Caci_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1084"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_703815_0_0_11"/>
    <dbReference type="OMA" id="CQSIENP"/>
    <dbReference type="OrthoDB" id="617515at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007575">
        <property type="entry name" value="SchA_CurD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04486">
        <property type="entry name" value="SchA_CurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="41953" checksum="E1DFCA0E0157C344" modified="2009-10-13" version="1">MAQTAPVLDERARPTDSRLRVVLLLDVHDGEQQSFLEAYEQMRYQVSAVPGHLTDQLCQSTDDPLRWLITSEWEAPEPFLSWLDSAEHREMVRPLSKCVRDTRSLRFTVFRETFGAQSVDSVLPPRERKGTGPVALGPGPDGIIRHALTFNVKPGSEQTVADILAGYTSPASQVDETTRLVRTSLFMRGNEVVRSVEVMGDLVAALRHVAAQPEVRAVEEAINPYLEQARDLNDPLAARDFFMRAALPAVHHHARAGKPTKKAEPQRFAYTYPARSGCGAAIAEFLARQDRAAMDDPKSPLVRSTVFQREDRVVRMVDMTVPATTDPATALGVMSPRAGAVLARLIRTPPDLRDDDGRRAAMANWELTTITDRRSPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q618</accession>
    <name>C7Q618_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785409.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1190"/>
    <dbReference type="EnsemblBacteria" id="ACU70115">
        <property type="protein sequence ID" value="ACU70115"/>
        <property type="gene ID" value="Caci_1190"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1190"/>
    <dbReference type="eggNOG" id="COG2872">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084984_0_0_11"/>
    <dbReference type="OMA" id="YWRKDAD"/>
    <dbReference type="OrthoDB" id="783542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="30926" checksum="4A9962BD3A318ED6" modified="2009-10-13" version="1" precursor="true">MAELSTTLVTFPAGATSGTATVLAVHALAEGAGVIVDTTPFHPLDHSWPDQPGDTGVLRAAGAEHAVADCVTGGVGPDGEFALGTDIPVRRGDESWQWLAVHILDKAEAPAPGTAVELRVDEARRAALSASHTGCHLMALALNEALTDRWRKEARTDGLNHPDFDSLAMDTSRIALDASTDRYRLGKSLRKKGFDPEGLRETLPELTEKINTRLAEWLSQDATIRIDTPGPELTARRQWVCELPERTVEIPCGGTHLHRLGELASLTAELTLSEDGSELVVVTTPKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q629</accession>
    <name>C7Q629_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine kinase</fullName>
            <shortName evidence="11">HK</shortName>
            <shortName evidence="11">HSK</shortName>
            <ecNumber evidence="4 11">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrB</name>
        <name evidence="15" type="ordered locus">Caci_1201</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785420.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1201"/>
    <dbReference type="EnsemblBacteria" id="ACU70126">
        <property type="protein sequence ID" value="ACU70126"/>
        <property type="gene ID" value="Caci_1201"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1201"/>
    <dbReference type="eggNOG" id="COG0083">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041243_0_1_11"/>
    <dbReference type="OMA" id="CANRIPH"/>
    <dbReference type="OrthoDB" id="610857at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="13">
        <location>
            <begin position="88"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="14">
        <location>
            <begin position="238"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU70126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="34300" checksum="00582330138622C6" modified="2009-10-13" version="1">MPSPVFRAAPVRVRVPATSANLGPGFDSLGLALGLYDEVMVRIADSGLRVDVAGEGADTVARDERHLVVRAMRAAFERLGARPPGLELVCANRIPHARGLGSSAAAICAGIVAARALTVGATLSDDAVLQLATEMEGHPDNVAACLRGGFTIAWLDQAGEISDAVGATARVLAIEPAPSLRAVAFVPDEGLSTEVARGLLPKLVPHAEAARNAGRSALLSAAVVQGRADLLLAATQDRLHQDYRAPAMPRTAALIAELRGAGHAAVVSGAGPTVLVLTTEDQVQTVIADGMKVAPAGWQAFGLAVDNAGAVSLNSTEGAGRGLDSDKDSNPRHGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F7</accession>
    <name>C7Q6F7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793721.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5133"/>
    <dbReference type="EnsemblBacteria" id="ACU73992">
        <property type="protein sequence ID" value="ACU73992"/>
        <property type="gene ID" value="Caci_5133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5133"/>
    <dbReference type="HOGENOM" id="CLU_1709938_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16346" checksum="A7A448DBADC4D546" modified="2009-10-13" version="1">MADSGDPIPGAYSGGLADPDVPVLREHFRDVTRWVIGDAVGDELTAAQSDALAEEIAVILASGLAPALHREVAHQTEKTIAELQNGPLSFDYHHRLLIDGLAVSDVVKLIDAVGRLVEAGVGDAISGLHETHQRMLYNAHDAWRAKHEESSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6G7</accession>
    <name>C7Q6G7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793731.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5143"/>
    <dbReference type="EnsemblBacteria" id="ACU74002">
        <property type="protein sequence ID" value="ACU74002"/>
        <property type="gene ID" value="Caci_5143"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5143"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_1_11"/>
    <dbReference type="OMA" id="ARTIEWH"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="841"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="903" mass="96296" checksum="B3B11797159DB261" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6K9</accession>
    <name>C7Q6K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793773.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5185"/>
    <dbReference type="EnsemblBacteria" id="ACU74044">
        <property type="protein sequence ID" value="ACU74044"/>
        <property type="gene ID" value="Caci_5185"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5185"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_0_11"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="21416" checksum="0B81F40F88B2E2AB" modified="2009-10-13" version="1">MAAPTIAAKIVVAGGFGVGKTTLVGAVSEIQPLTTEAEMTQAGVGLDDVHLIPAKRNTTVAMDFGRITIAEDLILYLFGTPGQERFWFFWEELSRGALGAVVLADVRRLGDAFAVIDFFEDRHIPHVIAVNQFDGAQVYGHEELRQALALEDDTPLLICDARRRDSAKGVLVTLLEHAITQQRMREDLPSDDRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q780</accession>
    <name>C7Q780_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1243"/>
    <dbReference type="EnsemblBacteria" id="ACU70168">
        <property type="protein sequence ID" value="ACU70168"/>
        <property type="gene ID" value="Caci_1243"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1243"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051674_0_0_11"/>
    <dbReference type="OMA" id="WRTDISK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="38941" checksum="CAA2CD747C4833CF" modified="2009-10-13" version="1">MSTPSQTGQPQQPGTASGQGPAGAGYAAAQDQVTTQQVPAPGYAPGQQQAGPGYAPGQQQANPGYGPPPQGPGFGGQPGFPGQPGQPGPGQPGQPGQPGPIQYAQPGYAPNQQSPNLAFAGADPFPQARASFGAALRSEWTKIRTVRSTFWTLLITMVITIGLGSLIALGSSSHPSPDDDFTANSMSGLFFGQLVIVVFGAMAITAEYSTGMIRTALTSQPRRGTLLGAKTVIVAAVALTVGLICSFASFFIATAIYSGHGIQLSLSDPGVLRAVIGGGLYMTVTALLAFGLGALLRHTAGAITTAVGILFVLFILVQFLPGNWRTDISKWIPFNAGLQIITTRPQDDMLSPWAGFGVFVAYAAVALIGGAIVMRKKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q796</accession>
    <name>C7Q796_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1259"/>
    <dbReference type="EnsemblBacteria" id="ACU70184">
        <property type="protein sequence ID" value="ACU70184"/>
        <property type="gene ID" value="Caci_1259"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1259"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_11"/>
    <dbReference type="OMA" id="ICPSIAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="7"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="273"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="40784" checksum="0C1F3043B632D1D1" modified="2009-10-13" version="1">MSATKSVIVAGARTPMGRLLGSLKNFSGADLGGVAIKAALERAGVAPEQVQYVIMGQVLQAGAGQIPARQAAVSAGIPLTVPAITINKVCLSGLDAIALADQLIRAGEFDIVVAGGQESMTNAPHLLPKSREGFKYGAVEMLDAMAYDGLTDPWENIPMGQSTEKHNARLGIERAPQDEFAARSHQRAAAAQKNGVFEAEITPVSIPQRKGDPIVFATDEGIRPDTTAESLSGLRPAFTKDGTITAGTSSQISDGAAAVVVMSKAKAEELGLEWIAEIGAHGNVAGPDTSLQSQPSNAIKHALGKQGLTVADLDLIEINEAFAAVGVQSMKDLGVDEEIVNVNGGAIALGHPIGMSGARLVLSLALELQRRGGGTGAAALCGGGGQGDALIITVPRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7V3</accession>
    <name>C7Q7V3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5261"/>
    <dbReference type="EnsemblBacteria" id="ACU74120">
        <property type="protein sequence ID" value="ACU74120"/>
        <property type="gene ID" value="Caci_5261"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5261"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_15_3_11"/>
    <dbReference type="OMA" id="PFRYMDT"/>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="9">
        <location>
            <begin position="322"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="503"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="717" mass="76439" checksum="F5B8C74B7CF4918D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7V8</accession>
    <name>C7Q7V8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Caci_5266</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793854.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5266"/>
    <dbReference type="EnsemblBacteria" id="ACU74125">
        <property type="protein sequence ID" value="ACU74125"/>
        <property type="gene ID" value="Caci_5266"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5266"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_0_11"/>
    <dbReference type="OMA" id="MFPMISE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="149"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="245"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="425"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU74125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="542" mass="55283" checksum="A2F519757329A2C2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q835</accession>
    <name>C7Q835_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ordered locus">Caci_5343</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793931.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5343"/>
    <dbReference type="EnsemblBacteria" id="ACU74202">
        <property type="protein sequence ID" value="ACU74202"/>
        <property type="gene ID" value="Caci_5343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5343"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033319_0_3_11"/>
    <dbReference type="OMA" id="LDMIVAN"/>
    <dbReference type="OrthoDB" id="1346419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="185"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="190"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="42692" checksum="8D2AF720515A40E8" modified="2009-10-13" version="1">MPLPNVVLGVGGGIAAYKACELLRLFTESGHGVTVVPTASALHFVGEPTWAALSGRPVATEVWERVHEVPHVRLGRHADLVVVAPATADLLAKAAHGLADDLLTNTLLTATCPVVFAPAMHTEMWENAATQENVATLRRRGLYVIEPAVGRLTGADTGKGRLPDPSAIFEYCRSLLARGTAEPDLAGLHVVVSAGGTREPIDPVRFIGNRSSGKQGFALAGTAAARGARVTLVAANTSLADPAGVDVVRVSTTAELRTAVRAAARDADVVVMAAAVADFRPREAAEAKIKKADDNSAPEIRLVQNPHVLRELGHSRSRPGQTVVGFAAETGDAQGTWLEHGRAKLAKYGVDLLIVNEVGVDLTFGADHSAAVVIGADGSEEPVADGPKERLADVIWDRVLKVRTPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D1</accession>
    <name>C7Q8D1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ordered locus">Caci_7290</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795847.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7290"/>
    <dbReference type="EnsemblBacteria" id="ACU76119">
        <property type="protein sequence ID" value="ACU76119"/>
        <property type="gene ID" value="Caci_7290"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7290"/>
    <dbReference type="eggNOG" id="COG0525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_2_11"/>
    <dbReference type="OMA" id="FATKLWN"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="33"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="616"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="815"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="820"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="534"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="882" mass="97911" checksum="AF385C343A2282C1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8P2</accession>
    <name>C7Q8P2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1384</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785601.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1384"/>
    <dbReference type="EnsemblBacteria" id="ACU70307">
        <property type="protein sequence ID" value="ACU70307"/>
        <property type="gene ID" value="Caci_1384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1384"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="DPESMFD"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="27"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28527" checksum="CAA3CBD69F58692D" modified="2009-10-13" version="1">MTTATVVAAGTTAAAPKPFKTIRHSAALAKRSLIKTMRTPEALLDVTLQPVIFLLLFTYVFGGAIAGSQSVYLQYLLPGILAQTIAMSATAIGVNMNTDISKGVFDRFRSLPIARSAPLVGAVLADFVRYALVAVITLTVGYAMGFRIHTNPLEAGAALLVSVAFALALSWVSVFLGMLARTPGAVQGMMILLVLPLSFGSNTFVQTNTLPGWMQAFVNVNPITHLAGVSRGLFLGGPVATHMLWTFGWIVGLTAVFMPLALRAYGRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q913</accession>
    <name>C7Q913_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3427"/>
    <dbReference type="EnsemblBacteria" id="ACU72333">
        <property type="protein sequence ID" value="ACU72333"/>
        <property type="gene ID" value="Caci_3427"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3427"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_12_11"/>
    <dbReference type="OMA" id="SFDTFTF"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="548"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="633" mass="67414" checksum="13DDCE625C331399" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q924</accession>
    <name>C7Q924_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3438"/>
    <dbReference type="EnsemblBacteria" id="ACU72344">
        <property type="protein sequence ID" value="ACU72344"/>
        <property type="gene ID" value="Caci_3438"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3438"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_12_11"/>
    <dbReference type="OMA" id="ALPGWHL"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="144"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="553"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="743" mass="79483" checksum="CD0A8D6BBFE3FF9C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q980</accession>
    <name>C7Q980_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792129.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3494"/>
    <dbReference type="EnsemblBacteria" id="ACU72400">
        <property type="protein sequence ID" value="ACU72400"/>
        <property type="gene ID" value="Caci_3494"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3494"/>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036902_11_0_11"/>
    <dbReference type="OMA" id="LANWAGV"/>
    <dbReference type="OrthoDB" id="655500at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="49065" checksum="04564D103E32E11E" modified="2009-10-13" version="1">MDDHAEVVELAVEVEQVGRVAAIDVAKASGMVCTRLPSETKAQRRVQRVWAVAATTDEITALGDHLVCQGVELVVMEATGVFWRPWFYLLEDRGLRVWLVNARDVKNVPSRPKTDKLDAIWLAKLAERGMLRASFVPPEPVRRLRDLTRLRRTLVEERTRYRQRVADVLQDACLKVADPKQGLTDLFGMSGRAILAALVAGQRDPKALAALAMGRAVVKTAYLEKALAGRFTAHHGFLVGKLLDLHDRLENDIAELNARIEAMIAELDRTPPPDDNHPDRLPLLDRLDEIPGVSREIAADILGETGFDMTVFPTGGHLASWAKLTPRTIQSGARNSHGGTGKGNRWIKGPLGQAAQAAGRTKTFLGARYKRIVKHAPAKKAQVAVARNILEIAWVLINDPDARFTDLGPDWHTRRTDETRKTRQHIRELEHLGYTVTLTKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q983</accession>
    <name>C7Q983_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3497"/>
    <dbReference type="ESTHER" id="catad-c7q983">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72403">
        <property type="protein sequence ID" value="ACU72403"/>
        <property type="gene ID" value="Caci_3497"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3497"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_745208_0_0_11"/>
    <dbReference type="OMA" id="VESADTW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="80"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="35151" checksum="66F49A724CEC1F4C" modified="2009-10-13" version="1" precursor="true">MTAPPAEIAPPLIPYRSRRRRWLRRVAKTVAVAFVASTFLSTAYNAATNARDSVPAGLTYVQAGDVSTRYREWGSSGTPIVLVHGFVESADTWQYLAPLLAAQGHRVYALDIDGWGYSQRVAPFDVGHQARQLDAFIEALHLAKPVLVGHSSGAAVAALAVLDKPGDASGVMFLDGDGLATGAGQKTPLTHLFLNPYRTTLMRLAVRSDTVIRAIYGATCGSGCPKLDAAGLDQWRRPLEVPGAEESLWSMVNLGVAGLPPTRLAELATLPIPKAVVFGGADSSYTPNSPQTTATRIGAPAPTIIPGAQHLTSVNSPAAVADAVAALEARAADSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q1</accession>
    <name>C7Q9Q1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76220">
        <property type="protein sequence ID" value="ACU76220"/>
        <property type="gene ID" value="Caci_7394"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7394"/>
    <dbReference type="HOGENOM" id="CLU_3197624_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="45" mass="4839" checksum="4C82A596A8A51406" modified="2009-10-13" version="1">MLSPLSSLSPDNPPNPRDPFGPLGPPVRPVPPVPQFRQPLSPSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA10</accession>
    <name>C7QA10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785702.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1485"/>
    <dbReference type="EnsemblBacteria" id="ACU70408">
        <property type="protein sequence ID" value="ACU70408"/>
        <property type="gene ID" value="Caci_1485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1485"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_0_11"/>
    <dbReference type="OMA" id="NIFCKIR"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="13"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18175" checksum="A7AE3A1783496F4F" modified="2009-10-13" version="1">MSSPEPAPATRAIDGLDARLLALLTEEPRIGILEASRRLGVARGTVQARLDRLQARGVVRGFGPLIDPAALGYTVTAFATLEIRQGRGAQVREHLAAIPELLEMHTITGAGDMLCRIVARSNADMQRVIDKLVSFEGIQRTSTVIAMANPVPFRVLPLTEVCATEHSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA20</accession>
    <name>C7QA20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785712.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1495"/>
    <dbReference type="EnsemblBacteria" id="ACU70418">
        <property type="protein sequence ID" value="ACU70418"/>
        <property type="gene ID" value="Caci_1495"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1495"/>
    <dbReference type="eggNOG" id="ENOG50331AG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1154775_0_0_11"/>
    <dbReference type="OMA" id="HIVNIMA"/>
    <dbReference type="OrthoDB" id="1986919at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025358">
        <property type="entry name" value="DUF4262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14081">
        <property type="entry name" value="DUF4262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="26613" checksum="B92AD97E4DB65511" modified="2009-10-13" version="1">MHSSHIVNIMAESPGHGGPAEPTGEHEERRRVTADIPPCHCVICDSESAVSQTLTAAENEAFADEDNLEDEEDDAVRALVPGWFGEAAAHVRRTGWTSIGIMPGTRTPGWAFSVGLWHSYRAPEVSLFGLLLPDMQQRVNRAGRLIRDNKPFGYDIEIDGILDAQPVVAKRVHPGWYPTLFGFAVGFYRGAVPPFVQLVWPDSHGLFPWQPGCGLRCRTVQPQLWLPPEVHPDGPWQNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG6</accession>
    <name>C7QAG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792194.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3560"/>
    <dbReference type="EnsemblBacteria" id="ACU72465">
        <property type="protein sequence ID" value="ACU72465"/>
        <property type="gene ID" value="Caci_3560"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3560"/>
    <dbReference type="eggNOG" id="COG5485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100997_5_2_11"/>
    <dbReference type="OMA" id="IEERGDW"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="17396" checksum="04266E88347D31FD" modified="2009-10-13" version="1">MSTTANKALVEKAIGILSGQTPEDFAQEAFAADYRDHNAPGDGGPARFLKVRAQLQTAFSDLKHEILASVAEDDIVSIHVQLTGTHTGVFQAGPRAIPATGNAVVIRSMHMLRVADGRITDNWAVRDDLTVLRAVGALPTPPAGGPGGPGGPGGAGGPAGPGGPGRPGAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB55</accession>
    <name>C7QB55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7521</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7521"/>
    <dbReference type="EnsemblBacteria" id="ACU76346">
        <property type="protein sequence ID" value="ACU76346"/>
        <property type="gene ID" value="Caci_7521"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7521"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="NILFAMQ"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="29"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="492" mass="51310" checksum="F99EC2411EC86E85" modified="2009-10-13" version="1">MSATTEEVLTPLPTTPSPDSSPDPRRWRMLPVILSAMFMAMFDYFVVNVAAPSFQHDLHTTDAGLELVVGGYGFAYAAGLITGGRLGDLLGYKRMFVGGMAAFTLASLACGVATSSTILIVARLVQGATAAAMVPQLLALINVIYPVHERPRAMAWFGATIGTGSVAGQVLGGVLLEANIFHWTWRPIFLVNVPIGLIAVLLALRWLPDTRGTHRPKFDPVGAIAIALSIGLALAPLILGRTEGWPVWTWVSLVGSVPVMIVAMRWEARLARVGGAPMVDLSLFKERTFSVGLALSGLMLAMFGGFMLAMTLFLQGGMHMSPVKAGLLFGPLGVAFAVTSLLARQVSGRYGARVIAIGAGLSTAGLVLLGIVLAWRGADLASWQLLPSMILVGAGNGLVLPSLVGSVLAGIKTKNAGAASGMLVTAQQFGGASGVTILGTVFFSVLGSHPGGFGGYVTAMRWVDAVDVVFVVAILAMAFLLPKQAAGMAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB95</accession>
    <name>C7QB95_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="10" type="ordered locus">Caci_7561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796111.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7561"/>
    <dbReference type="EnsemblBacteria" id="ACU76386">
        <property type="protein sequence ID" value="ACU76386"/>
        <property type="gene ID" value="Caci_7561"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7561"/>
    <dbReference type="eggNOG" id="COG0166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017947_3_1_11"/>
    <dbReference type="OMA" id="IGVWYIN"/>
    <dbReference type="OrthoDB" id="417261at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="519"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="531"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="545" mass="60727" checksum="8A5BA75F5C79472C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS0</accession>
    <name>C7QBS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792268.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3636"/>
    <dbReference type="EnsemblBacteria" id="ACU72539">
        <property type="protein sequence ID" value="ACU72539"/>
        <property type="gene ID" value="Caci_3636"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3636"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061724_0_0_11"/>
    <dbReference type="OMA" id="YWDGYFA"/>
    <dbReference type="OrthoDB" id="1438002at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="29317" checksum="930D7A386832A987" modified="2009-10-13" version="1">MPQAQVKVHRTSELIEPIGAVSFSEVPNEAFLAVGMRNYWDGYFAGRAAPLGLAPAEVVHAVFYSFAEGEVARHIPWVWGKISPLEALAVRERGSAAALRQRIGQLADSPGLERVLDLAVRAAVSAPVEGRALYAGLRALAVPEEPVARLWHAATLLREHRGDGHNAALLAHRIGGTEAHVLMALALGMKAHEFGRLHHLPKARLAAVLDGLRERGLVDDAGEFTDAGRATRERIEDLTDELAAPAYDVLSADELDELIAGLEPIAAAVEAAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW0</accession>
    <name>C7QBW0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3677"/>
    <dbReference type="EnsemblBacteria" id="ACU72579">
        <property type="protein sequence ID" value="ACU72579"/>
        <property type="gene ID" value="Caci_3677"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3677"/>
    <dbReference type="eggNOG" id="COG0662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2261601_0_0_11"/>
    <dbReference type="OMA" id="CRPGMGF"/>
    <dbReference type="OrthoDB" id="1745958at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12950" checksum="B068618F0ACC0AC1" modified="2009-10-13" version="1">MTVETQTPTLVGIDFDAMPWEKWVKAGADGRVKIAYTQGFRVRLMELPAGFDEQEWCTRGHQGYVLSGEFTILFDDRAVSCRPGMGFIIPGTERHRSRGSGTEPTLVYVIDEVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW8</accession>
    <name>C7QBW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3685</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792316.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3685"/>
    <dbReference type="CAZy" id="GT87">
        <property type="family name" value="Glycosyltransferase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72587">
        <property type="protein sequence ID" value="ACU72587"/>
        <property type="gene ID" value="Caci_3685"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3685"/>
    <dbReference type="eggNOG" id="COG5650">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034641_0_1_11"/>
    <dbReference type="OMA" id="VARWITW"/>
    <dbReference type="OrthoDB" id="1362354at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="45099" checksum="63548EAA1A950A24" modified="2009-10-13" version="1" precursor="true">MLEQTSRPTWPARLLPLLGAAVVAAALTGQVMLLLGQSIPYFMSDFLVYRGGGHAVLHDVRVYQIGVATPVSQNMQFIYTPFAAVVLAPLAALGVGASETLWTFLSLLAIAATIWLSLRVSGVSSRRLLTAGTVGGMFVASLLSPVSFNLILGQINVFVMLLILLDFAPGTPERWRGVGIGVAAGLKLTPLLFVVYLVLTKRWAAAGRSVVAFAATILLGFAVIPADSRAYWLHGMFHDTSRMVPFPTLVNHSLPGLIARLDHTTTPSNGALAIATVVGVVFLAGAVWAYRRGQDTVGMLVIAFTAQLVSPITWMHHGVWVIPALIWLSLARWRSGTLLPWVVLSLATAWYLAPIWLIGQGSLTARAPHQWTTSGEIITALTGNLVPAVIAIVLMPVWLPKLREPAKEESGVEEPTKATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC49</accession>
    <name>C7QC49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794226.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5638"/>
    <dbReference type="EnsemblBacteria" id="ACU74497">
        <property type="protein sequence ID" value="ACU74497"/>
        <property type="gene ID" value="Caci_5638"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5638"/>
    <dbReference type="HOGENOM" id="CLU_1861607_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14156" checksum="B24389BFD8B34279" modified="2009-10-13" version="1" precursor="true">MIVDGSYTAWVRPTRRVHFALSLGMTLTGAILIAAGAAGGSGAARPAPLIGRTADSFVSGDNGASGSQVPAAPLLPVAPPQVKTPPHPVAKPHPKSRPHPHHTMSTPTRPAELLRPAAPPVRSVPSSAEPRPHRLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCK0</accession>
    <name>C7QCK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796188.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7639"/>
    <dbReference type="EnsemblBacteria" id="ACU76463">
        <property type="protein sequence ID" value="ACU76463"/>
        <property type="gene ID" value="Caci_7639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7639"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056943_2_0_11"/>
    <dbReference type="OMA" id="QATRREW"/>
    <dbReference type="OrthoDB" id="1036370at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="247"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="33765" checksum="1B15186A415EAFE1" modified="2009-10-13" version="1">MLGSLGLDPLAQAVYSAMLADPAVGVRELKERLGQEEARIRDTLDRLVELALLRPSREQPGGLYPVSLVAGMQLLVQRQEAELAAGRDAVAAGRAAAADRQRAEQLFGLDAVQSELEQLLAGAAVEVLSMVPGSAVPAATLKAAESLDQDMTRRVRSRILYHSTVRQDPTTIAYGRWMAEQGSEVRLSPSVTRRLLIVDGKTAVVPIKPNEASVGALCVREPGLIDQLTALFELIWTEAVPLGMPAKAESPAGLSPTDRHLLRLLADGLTDEAAAKRLGISARTVRRIMADLMDRLGAESRFEAGVEAARRGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD11</accession>
    <name>C7QD11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786015.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1800"/>
    <dbReference type="EnsemblBacteria" id="ACU70721">
        <property type="protein sequence ID" value="ACU70721"/>
        <property type="gene ID" value="Caci_1800"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1800"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="VYLCCKA"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="26981" checksum="B69274CBB89106FF" modified="2009-10-13" version="1">MTERLAGRVAVITGGTGGIGMATARRFAAEGAHVVLADLDEASGKAAAEEVGGLFVRTDVTDAERVAALFQAAVDTYGSVDIAFNNAGISPPDDDSILDTGMEAWDRVQKVNLTSVYLCCKAVIPHMLRQFEATGRGGSIVNTASFVATLGSATSQISYTASKGGVLAMSRELGVQFAKQGIRVNALSPGPVNTPLLKELFAKDPERAARRLVHVPRGSFAEPEEIAAAVAFLASDDASFVNASNFLVDGGISGAYVTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDJ6</accession>
    <name>C7QDJ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5762"/>
    <dbReference type="EnsemblBacteria" id="ACU74620">
        <property type="protein sequence ID" value="ACU74620"/>
        <property type="gene ID" value="Caci_5762"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5762"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107911_0_0_11"/>
    <dbReference type="OMA" id="WNYLAID"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="22768" checksum="0785FEC18B6A90C6" modified="2009-10-13" version="1">MVVKREGPTHRQRQALATKEQIAAAGRKLFAERGYVATTITAISEAADIPVPTIYSAFGNKAAILKDITQRAVAPLDVKGRYEQVVADPDPVSGLRRAAQMQREQFETMYDVMTVTMEAVRTDPEIAEMLRGIMASRERAYRAHLETVAAHLAPAMTVDEGVDVYVTLVLPEIYHSLVVERGWSPDRYETWLGDNLIRQLLGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC0</accession>
    <name>C7QEC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lytic transglycosylase catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786105.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1891"/>
    <dbReference type="EnsemblBacteria" id="ACU70811">
        <property type="protein sequence ID" value="ACU70811"/>
        <property type="gene ID" value="Caci_1891"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1891"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3953">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083020_0_0_11"/>
    <dbReference type="OMA" id="PAQGKHR"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983080" evidence="2">
        <location>
            <begin position="33"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="89"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="30540" checksum="B02A73596B57A236" modified="2009-10-13" version="1" precursor="true">MRTPLVLGRRSRGLTLTAAALGAVAVPSIASAAPALAATPHARPAAAPALAPAPASAVAAAVAASAPAPAQAAPVAAVAPKAAAAPKAATYTVRPGDTLSGIAQSKLGDGSKYPEIFKLNTGKAQADGHKLQDPNLILIGWVLNLPNGSATPAAAKPAVQSAPAKPAQPTQKTTTQTQSYSTTSASASSYANNLDGWIKQAISILNSHGYYVSYNAIYQTVMHESAGNPSATNGWDSNAAAGHPSIGLMQTIAPTFNAYALAGHGNIYNPVDNIIAGVRYAAAVYGSLDSVVAARCGGSCWYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET2</accession>
    <name>C7QET2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792581.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3976"/>
    <dbReference type="EnsemblBacteria" id="ACU72852">
        <property type="protein sequence ID" value="ACU72852"/>
        <property type="gene ID" value="Caci_3976"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3976"/>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084115_2_1_11"/>
    <dbReference type="OMA" id="ISDFKYT"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981583" evidence="2">
        <location>
            <begin position="27"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="3">
        <location>
            <begin position="60"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="14598" checksum="7810A825828604EF" modified="2009-10-13" version="1" precursor="true">MLRTLRRVAIPAAALLLAAAGCSSTASTGNSQPTTPPSSPTTPSTTGPASPSAPSTTTAPSQAPTTAAQIVIDNFAFSPANLTVHPGQSITVVNHDSTTHTLTAGSGGAFDTGAINPGKSATITAPATAGTYPYVCSIHASMHGTLTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD4</accession>
    <name>C7QFD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7888"/>
    <dbReference type="EnsemblBacteria" id="ACU76711">
        <property type="protein sequence ID" value="ACU76711"/>
        <property type="gene ID" value="Caci_7888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7888"/>
    <dbReference type="eggNOG" id="ENOG502ZBG0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537146_0_0_11"/>
    <dbReference type="OMA" id="WAFRFAW"/>
    <dbReference type="OrthoDB" id="1312599at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="56763" checksum="D562EA65B19DF0F4" modified="2009-10-13" version="1">MAAKRDERRALADAHLHLDDVEKWFIKRGLPHFIENYKATEDVFNRALPLFVVLVVFQMGLELSSKTVTWQDRLIGGAVGLAAVVVVFLAANLVRQRQRWYRWPRKIGPVEITLLVLLGPVVGKLSGAGWGAVVADFLANILVLALVYLLTAYAILPVLKWAVRHSIDELGNLGNLASKALPMLALFGTFLFLNVDMWHIASSFEQRSQLWFTTLFFAAITFLFLMVRLPGEVRNLQGDYYLEAVVAASADTPLHEHVGDLDDELPQLRTNRRQQVNMLFVLAFTQVIQILLLSVVVFVYFVSLGKLAVTNGQVADWLKTPECPPNPHLGSYKITGHSSPEDVMHACGFATKEQADTWLKIISPGKLFGFYARIPGTNLEFSEPLLRTAILLTTFSAFFFAVSAVTDEAYRKDFFESITGRIAKCLTVRCGYVNLYEKATRQALNESGVDPKALDEDHRRTVQVPSMVADPNTRTQQLSSYQPGSGYLTMTDPGPEEPLRRRSMQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFG6</accession>
    <name>C7QFG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796468.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7920"/>
    <dbReference type="EnsemblBacteria" id="ACU76743">
        <property type="protein sequence ID" value="ACU76743"/>
        <property type="gene ID" value="Caci_7920"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7920"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="MIGYFET"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="87"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="33315" checksum="2802D610572AC907" modified="2009-10-13" version="1">MTAQTINRTAPRASGDRRRPPRWGSVASQAFLICACVLWLLPIAFALYVALRPYSETQKYGYVSLPHHLTLKNFSDAWTQSDMLHYFWNSVLITVPSVIIVLALASGLAFVLTRVNVKINVALLIVFTAGNLLPQQVIITPLYRLFLQIHLPTFLAGSGLLYNSITGLIVINVAFQLGFCTFVLSNYMKSIPDEMYEAALVDGAGLWTRFRKLTVPLCRPALAALATLLTTWIYNDFFWAITLMSSGNKRPVTSALANLQGQFVSNQNLIAAAAMIAAIPTLVVYVLLQKQFIAGLSLGSSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR3</accession>
    <name>C7QGR3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794672.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6087"/>
    <dbReference type="EnsemblBacteria" id="ACU74943">
        <property type="protein sequence ID" value="ACU74943"/>
        <property type="gene ID" value="Caci_6087"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6087"/>
    <dbReference type="eggNOG" id="COG3467">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123922_3_1_11"/>
    <dbReference type="OMA" id="PMWVGLD"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019920">
        <property type="entry name" value="F420-binding_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03618">
        <property type="entry name" value="Rv1155_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="3"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14275" checksum="59CDFEA6FC824711" modified="2009-10-13" version="1">MKLDPEVSRILDAAPLVHLATLMPDGAPHSVTIWAAPYGDRIAILTGPDSLKARNMRRDPRVALSLTPNDNPFQPVAVRGRVVEWIEGDAAWEIIDPIAMKYLGRPYDRSVERVVLLIEPERQTVGVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU1</accession>
    <name>C7QGU1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6116"/>
    <dbReference type="EnsemblBacteria" id="ACU74971">
        <property type="protein sequence ID" value="ACU74971"/>
        <property type="gene ID" value="Caci_6116"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6116"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_4_2_11"/>
    <dbReference type="OMA" id="WIFLGEV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="34239" checksum="F021E16A0A6B9F8F" modified="2009-10-13" version="1" precursor="true">MSAQQRSPYLLLAVTMLLWGGAFSSSETVVDHVPHTVAATLRFGGGAIALLIARALTGRRGVPRPKVGMRASVRACLAGVLGVFAYNGFFFWGLSLAPSLDGGILIPVMSPVLTTSFLLISGREKASRRRLIGLALGLGGAAAYLIGANSAGGGSHRLLGDLLYVLSAVCWAAFTLAAPKVLAGIEPLTAMAYATCTGAVLLALVAAPDMGSVQWGALPSEVWLNVAYLAIGATAVANVLYYRGVAAVGPASASLMMFLVPAVNTACATLFLGESFTPVQAGGAVVLLVGAALAGRARISVRSWRSWRSWRHPAARVRPALRRRRQTTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH56</accession>
    <name>C7QH56_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796631.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8083"/>
    <dbReference type="EnsemblBacteria" id="ACU76906">
        <property type="protein sequence ID" value="ACU76906"/>
        <property type="gene ID" value="Caci_8083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8083"/>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_5_1_11"/>
    <dbReference type="OMA" id="DPRKRQC"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="24280" checksum="096295283B73DA36" modified="2009-10-13" version="1">MAETKTVVHLMRHGEVYNPDGILYGRLPGFRLSDLGRKMAERVADHLADHDVKAVVASPLQRAQETAAPIAARHDLEIGTDERLIEAANFFEGKKFSVGDGVLKRPAVWFKLWNPFKPSWGEPYKEQVKRMHAALLAAAELAPGHEVVLVSHQLPIWISRLAAEHRSFFHDPRKRECTLASLTSFEITDGRITAVRYSEPAKDLLPVKNTKKFVAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ1</accession>
    <name>C7QHQ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2157</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2157"/>
    <dbReference type="EnsemblBacteria" id="ACU71076">
        <property type="protein sequence ID" value="ACU71076"/>
        <property type="gene ID" value="Caci_2157"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2157"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039404_3_0_11"/>
    <dbReference type="OMA" id="KFKETRM"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041280">
        <property type="entry name" value="Big_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17964">
        <property type="entry name" value="Big_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983231" evidence="5">
        <location>
            <begin position="28"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Big_10" evidence="7">
        <location>
            <begin position="82"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="6">
        <location>
            <begin position="269"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="42769" checksum="8E9E4A37D9BDA1C0" modified="2009-10-13" version="1" precursor="true">MRRLQKLAVAAAVAGLTAACGGGGSSSKTTAVAPVGNGSSASSSASSPGGGSQSTAPSAPSSSSSAPTSPALVVIKPAANSSGVDPSSPIAVSVANGKLTSVTAQLSGGDAVSGTLDPSGASWTSANPVGIGHTYKVTAVAVGDDGKQQTATSQFTTSTPGNTYAGTYTPDPGTTYGVAQPVSITFDKPIPDKAAVEKQLTVTSDPPVAGSWHWFGSERVDFRPQQYWAPGTKVTLHMRLDGVKSGSLYGKQNRDVTFTIGRSLIATMNAATKRMTVTTGGKTTTLLTSSGKPGFETWNGTMVVLEKDQDIRMNSTTVGIFGVNAYDIPNVYWDVRLTPSGTFVHAAPWNAGKFGNVNGSHGCVGLSTSDAEWFFNQVIPGDPVTVVNSKDTVRADNGFGDWNLSWSDWIAGSALPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW4</accession>
    <name>C7QHW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2220"/>
    <dbReference type="EnsemblBacteria" id="ACU71139">
        <property type="protein sequence ID" value="ACU71139"/>
        <property type="gene ID" value="Caci_2220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2220"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006842_7_0_11"/>
    <dbReference type="OMA" id="YPCYDPA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980994" evidence="3">
        <location>
            <begin position="29"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="48"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="31093" checksum="9FC4DDCDD798FA11" modified="2009-10-13" version="1" precursor="true">MTRLRRRVARMAAWGVAGVLTVAGVAAATALGAPAKPAAAVLRPIPRIVGGAAAPDGAYPFMAALQQWAGNGYLTICGGTLIAPDEVLTAAHCVDQWSVGQTASTGEAKERIIVGRTVLSASDGAIRVPAAIHMDPTWDSATESDDAAVVQLDTPIADVASPTMPPSGNQSYEHAGTPARAIGWGSTQAQGPADVGGGVYPDELRQVDLPLVGDGPCRSVFDGIRNPALYPQEMLCAGGDGHHDACTGDSGGPLLAALPGGTWELIGVTSWGNGCAVPGTPGVFTRLSAPDIHSFVATASDANDFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI02</accession>
    <name>C7QI02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792776.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4183"/>
    <dbReference type="EnsemblBacteria" id="ACU73047">
        <property type="protein sequence ID" value="ACU73047"/>
        <property type="gene ID" value="Caci_4183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4183"/>
    <dbReference type="eggNOG" id="COG2229">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077970_1_1_11"/>
    <dbReference type="OMA" id="VLYMFGT"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="21196" checksum="970116944170C17A" modified="2009-10-13" version="1">MGSVNSSEVAYLPGTVTRSVKLLIAGHFGAGKTTFVGSVSEIRPLRTEEPITEASLGVDDLAGLPKKTSTTVAMDFGRRTFGDVALYLFGTPGQQRFLPLWDELARGAAGALVLVDTRRLDHADEILSAVEKRGLPYTVAVNQFDGARRYPPEQIREALDLAPTTPLTVCDARDQASSAKALIVLVEHLTSRPETFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI59</accession>
    <name>C7QI59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4240"/>
    <dbReference type="EnsemblBacteria" id="ACU73104">
        <property type="protein sequence ID" value="ACU73104"/>
        <property type="gene ID" value="Caci_4240"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4240"/>
    <dbReference type="HOGENOM" id="CLU_3096964_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045825">
        <property type="entry name" value="RamS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19402">
        <property type="entry name" value="RamS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="51" mass="5143" checksum="FDAAD86A1792C64D" modified="2009-10-13" version="1">MTEEMTLLDLQGMEQTETDSWGGSGHGGGGDSGLSVTGCNGHSGISLLCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIK8</accession>
    <name>C7QIK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6231"/>
    <dbReference type="EnsemblBacteria" id="ACU75085">
        <property type="protein sequence ID" value="ACU75085"/>
        <property type="gene ID" value="Caci_6231"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6231"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="17"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35458" checksum="A444C406D5154CD6" modified="2009-10-13" version="1">MTSSPSTMRAVRLSGPGPVDNLELTTVPLPPEKDGWVRIRVEAFGLNRSELKLRLGVSVGVSFPRVPGIEAAGTIDAAPADSGLVRGQKVVAMMGDMGRTYDGGYAEYTSVPLSQVIPIDTDLPWEVLGALPEMVQTAYGSLTVGLDIQPGQTVLIRGGTSSVGLAAAALAGWRGCTVLSTTRKADRLALLKERGVDHPLLDDGDVAAAVRELYPDGVDAALDLVGTPTLPDTLRAVRVHGTACFGGSLSNQYSVRDFSPNEYLPRGVRLAGYFGDASDLPQDVFQEILDAVAAGQLTFPVDRVYDGLEQVRQAHDDMEHDRATGKLVVRVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL7</accession>
    <name>C7QIL7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6240"/>
    <dbReference type="EnsemblBacteria" id="ACU75094">
        <property type="protein sequence ID" value="ACU75094"/>
        <property type="gene ID" value="Caci_6240"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6240"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_1_1_11"/>
    <dbReference type="OMA" id="WDMAAPP"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="43324" checksum="8D134905AC70EAA8" modified="2009-10-13" version="1">MVVGAGHAGLAASHFLTAAGIDHLVLERGEVANSWRRERWDSLRLLTPNWLTRLPGHRYQGPDPDGYMTASEVADFIDGFAKSSQAPVRAGMAVTSVRREGDGYRVRTDQGEIQTRTVVIASGACNLPIVPAISSAVPESIRQLTPFDYTGPDELPDGGVLVVGASATGVQLAAEIRRTGRPVVLSVGEHVRLPRVYRGRDVLWWMDASGVWDQRHDELDDVDRARGLPSPQLAGTADRGDLDLNTLMAMGVEPVGRWAAVRDGRALFSGGLRNVCSLADLKMERLLATFDAWAPDAYDESEPVVPTQIPASPRLQLDLRSGEIETVVWATGFRPDYSWLEVSVLDGKGRLRHTGGVVDSPGLYALGLPVLRRRKSTFIHGAEDDARDVIDHLAGYLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ2</accession>
    <name>C7QIQ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796677.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8129"/>
    <dbReference type="EnsemblBacteria" id="ACU76952">
        <property type="protein sequence ID" value="ACU76952"/>
        <property type="gene ID" value="Caci_8129"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8129"/>
    <dbReference type="eggNOG" id="ENOG5032SVJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108860_3_0_11"/>
    <dbReference type="OMA" id="FDMSATR"/>
    <dbReference type="OrthoDB" id="2048400at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021678">
        <property type="entry name" value="DUF3263"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11662">
        <property type="entry name" value="DUF3263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12725" checksum="62D98A9C6050418F" modified="2009-10-13" version="1">MNTSEPGGGLTDRDRAILAFEKQWWRNAGSKEQAIRERFQISATRYYQLLNALLDDEAALALEPEVVKRLRRLRAARQRARSGRVKRVADIGSDPDGEPPPVSNEGHDQDRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX2</accession>
    <name>C7QIX2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8199</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796747.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8199"/>
    <dbReference type="EnsemblBacteria" id="ACU77022">
        <property type="protein sequence ID" value="ACU77022"/>
        <property type="gene ID" value="Caci_8199"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8199"/>
    <dbReference type="eggNOG" id="COG4565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_39_1_11"/>
    <dbReference type="OMA" id="DVHGLQL"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024187">
        <property type="entry name" value="Sig_transdc_resp-reg_cit/mal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45526">
        <property type="entry name" value="PTHR45526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006171">
        <property type="entry name" value="RR_citrat_malat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="24541" checksum="667ADF9F95214C13" modified="2009-10-13" version="1">MIRTLVVEDDPVLAEAHRVYVERVPGFEVADVARTGADALRVLAARDVDLVLLDVYLPDMTGIDLCRTLRARGEATDVIAVTSARDLATVRAAVSLGIVQYLIKPFQFATFRGRLEAYAEFRRATESADANSGALQQDELDRMLDGLRSPRPAQLPRGLSDSTLAALVGILKAASPLTAAELADRAGVSAPTTRRYLEYLTARRLVSGQPRYGGPGRPETVYQWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ04</accession>
    <name>C7QJ04_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784441.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0191"/>
    <dbReference type="EnsemblBacteria" id="ACU69146">
        <property type="protein sequence ID" value="ACU69146"/>
        <property type="gene ID" value="Caci_0191"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0191"/>
    <dbReference type="eggNOG" id="COG1831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047695_0_0_11"/>
    <dbReference type="OMA" id="ISEFGTC"/>
    <dbReference type="OrthoDB" id="785625at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="36831" checksum="F2192463BE5B1CF0" modified="2009-10-13" version="1">MRGKGVNYDTGFFPGGQDSRPDFDPETARRELRVIAEDLHCTAVRISGALPDRLEAAAQAAADAGLEVWFAPFPCEASREDLLELLADCAQRAERLRAAGAEVVFVAGCETSLFCPGYFDGDDSYARIETLGNGGMALWSRLGEIMASFNGYLVEAAATVREHFQGKVTYAAGPWEFIDWAPFDFVSVDAYRSAENRDKFADQIRAHFKHGKPVVATEFGCTPYVGSGDRGGMAWAILDDSVEPPVVNGDYLRSEDEQSAYFTELYDVFEEAGVDSAFWFTFATFRALHDPSDPRKDLDLAAYGTVKMTGPDTPELNWEPKKVFHTIAERYAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJF4</accession>
    <name>C7QJF4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786470.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2259"/>
    <dbReference type="EnsemblBacteria" id="ACU71177">
        <property type="protein sequence ID" value="ACU71177"/>
        <property type="gene ID" value="Caci_2259"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2259"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="YSMINRW"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="34"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36945" checksum="6AF946BD3FFA89FF" modified="2009-10-13" version="1">MNVLSTYAADPERYDDRMPYRRSGLSGLKLPLVSLGLWHNFGDGKPLEDQRAVLRRAFDLGVTHFDLANNYGPPYGSAETNFGHVYAQDFRPYRDELVISTKAGYDMWPGPYGEWGSRKYLLASLDQSLTRMGLDYVDIFYSHRFDPETPLEETMGALASAVQQGKALYVGISSYNSEQTREAAALLRGMGVRALIHQPSYSILNRWIEEDSLLDATAETGMGCIAFSPLQQGLLTSRYLDGTIPTGSRASIGRFLSKDNLTPEVLTKLRGLNELAGKRGQSLAQMATQWVVRDPRMTSALIGASSVAQLEENVAAVSGPEFSAEELAAIDELALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG2</accession>
    <name>C7QJG2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786478.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2267"/>
    <dbReference type="EnsemblBacteria" id="ACU71185">
        <property type="protein sequence ID" value="ACU71185"/>
        <property type="gene ID" value="Caci_2267"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2267"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_11"/>
    <dbReference type="OMA" id="PVCLRYG"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="5">
        <location>
            <begin position="31"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="45562" checksum="A2CED20670173C2C" modified="2009-10-13" version="1">MVINSQFLDTDTIRKDFPILQRLVHGDKPLVYLDNAATSQSPQQVIDSIVEYYSLHNANVHRGIHVLAEEATALYEGGRDKVAAFINAPREEVVFTKNSSEALNLVANVLGWAGEPYGIRPGDEIVISEMEHHSNIVPWQLTAERIGAKLRWFGITDEGRLDLSNLDEVINERTKVVSLVHISNILGTVNPVETIVKRAHEVGALVVLDASQSAPHLPLDVQALGADFVAFTGHKMLGPTGVGVLWGRRDLLEELPPFLGGGEMIQTVTMEKSTYAGLPHKFEAGTPPIAEVIALGAAVDYLNGIGMENVAAHEHAITEYALKRLQEVEDLRIIGPATNQDRGAAISFTLGDIHPHDVGQVLDEHGIAVRVGHHCARPVCVRFGIPATTRASFYLYSTPAEVDALVEGLDQVKRFFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK00</accession>
    <name>C7QK00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4374"/>
    <dbReference type="EnsemblBacteria" id="ACU73238">
        <property type="protein sequence ID" value="ACU73238"/>
        <property type="gene ID" value="Caci_4374"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4374"/>
    <dbReference type="eggNOG" id="COG1230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_0_0_11"/>
    <dbReference type="OMA" id="HDLHIWE"/>
    <dbReference type="OrthoDB" id="948593at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="36405" checksum="521CF49FBEB65D83" modified="2009-10-13" version="1">MSEQIHEHAEHDHGDGHGHGHERGHGHSHGVALDADRRWLLIGLALILGFMAVEVVVGVLAHSLALLSDAAHMLTDAGSILLALFAMRLAARPARGGYTFGLKRAEIMSAQANGVTLLVLSVVLAFEAVRRLINPPEVTGGLVLATALVGVAVNIAAAWSISKANRTSLNVEGAFQHILTDLYGFIATAVAGLVVVLTGFARADAIATLVVVALMLKAGLGLVTAAGRIFLEAAPAGVDPDEVGDQMAAVEQVIEVHDLHIWEITSGQAAMSAHVLVVPGGDCHKVRRVLQRQLLAEHGIGHATLQVDHLGDAEAEILQISHTVPDGDLGHCEDSHGPVHRTGPHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK06</accession>
    <name>C7QK06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792973.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4380"/>
    <dbReference type="EnsemblBacteria" id="ACU73244">
        <property type="protein sequence ID" value="ACU73244"/>
        <property type="gene ID" value="Caci_4380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4380"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028177_0_0_11"/>
    <dbReference type="OMA" id="RLTEHAT"/>
    <dbReference type="OrthoDB" id="525192at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="33"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="557" mass="59934" checksum="D61E1442CA6DD6BF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK53</accession>
    <name>C7QK53_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794856.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6273"/>
    <dbReference type="EnsemblBacteria" id="ACU75127">
        <property type="protein sequence ID" value="ACU75127"/>
        <property type="gene ID" value="Caci_6273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6273"/>
    <dbReference type="HOGENOM" id="CLU_873439_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981069" evidence="1">
        <location>
            <begin position="28"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="33383" checksum="BF5FB0DC4A99B7DC" modified="2009-10-13" version="1" precursor="true">MSVTRRQFITTGGAAAGIAVTALTATALGASSATARSRVLTTPTWMLAGAGFANLAAKSLGGDPAVCRRAFNTGRTWFITTYTGDTTIPSPVPAGYTGVAVLKFKCYQDGSTGLVDALAAGLPSWVTAVQYDAESWAQTPDLEQGAWLLNPHTQTSYAQLFCATAHSHGLKVVLTPGNDLCNNSPNPAYPQRKPQYPVTSKDAGQNYNAFIRHNMAAAAQYLQPGDIFEYQAQQLELDTEAYTTVTTKVAEQVEAANPATLFLAGLGRSKPPSDGANCADLAAAATGVADTAAGFWLNVGAYSSQVRPMICALRKLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK97</accession>
    <name>C7QK97_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794900.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6317"/>
    <dbReference type="EnsemblBacteria" id="ACU75171">
        <property type="protein sequence ID" value="ACU75171"/>
        <property type="gene ID" value="Caci_6317"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6317"/>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_11"/>
    <dbReference type="OMA" id="GLNETCI"/>
    <dbReference type="OrthoDB" id="164380at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="28"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="509" mass="54983" checksum="AC1AC09734E7CFC6" modified="2009-10-13" version="1">MADSIINRIVADRPAGEGTLTVTGLGHRTTLPLAEFHDRARTVAGVLRSRGIGAGDRVGILAANRLEWALLDVACLMIKAQTAGFEPGKFSPDADLIEGYDLDLLYTDVPLPDDAPRQVLPISTIAGDVENGVEPDAADFEPAVWSPTDCTTVKFTSGSTGIPKGLEATVGSIDSSLHAVQSLFDHQPGDNILTFLPLSLLQQRYWLYSALYWGHDITITTYQSVYAVMSTIRPTVVMGVPAFFDTAKRHLEDRLADGIEPEKAAHELFGDRVRYLWTGSAPADPATLRFFDEIGLPIFEGYGLNETCITTKNHPGAHRVGSVGKPLPGKEILIDAEGVVCVRSDHPVNTAYTYAAAGDSARMFKPGGVVRTGDLGRLDEDGFLYILGRADDVIVLDNAKKIIVRPIETRFRDTGAIAECVLYHPSPAGLVAVVSPHPGPIDTAAIAEALEKVNAASERDERICRVIVAAEPFTIENGLLTSQFKPIRGRIADRHRALIDDPKVGIHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD3</accession>
    <name>C7PVD3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784584.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0336"/>
    <dbReference type="EnsemblBacteria" id="ACU69289">
        <property type="protein sequence ID" value="ACU69289"/>
        <property type="gene ID" value="Caci_0336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0336"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_1_0_11"/>
    <dbReference type="OMA" id="HTTRSEE"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="219" mass="21322" checksum="136004B94DF7E93C" modified="2009-10-13" version="1">MAGETVITVVGNLTDDPELRFTPSGAAVANFTVASTPRTLDRQTNEWKDGDALFLRCSIWRQAAENVAESLTRGMRVIVSGRLRQRSYETKEGEKRTVVELDVEEIGPSLKYATAKVTKANRPGGQGGPGGGGGGGWSGNSGGGGNSGSAGGGGGWGGNSGGGGNSGGGGGGGGSWGGNSGGGGGNSGGGNQGGGNDPWASGGGGDGGWGGYGNDEPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVF9</accession>
    <name>C7PVF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0362"/>
    <dbReference type="ESTHER" id="catad-c7pvf9">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69315">
        <property type="protein sequence ID" value="ACU69315"/>
        <property type="gene ID" value="Caci_0362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0362"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_2_11"/>
    <dbReference type="OMA" id="GWPELAF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="35775" checksum="282A6B6626069A26" modified="2009-10-13" version="1">MNKRSVMVGGLRMNVVEAGSGPDVVVLLHGFLNYSYSWRHQVRDLAAAGYRVLAPDLRGYGETGCPEDVEQYSMLHLVADVVGLLDAFGIERATVVGHDWGSVLAWHTALLRPDRVRGVVGLSVPYVPRADISLLTAMRERFGDLYYMQYFQEVGPADRELARDVAATFRSVLSSGSEPWNPVLPEGGGWLDCLPDKGIPDWLTAADLDAHVAAFERSGFTGALNWYRNIDRNHELTAAWQGAKIQVPALFLYGTRDAFGRYASELIDDLPRSVPDLRSVVRLDAGHWVQQERPDEVTAALVDFLERDRDRDGARPMPVGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI0</accession>
    <name>C7PVI0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784631.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0383"/>
    <dbReference type="EnsemblBacteria" id="ACU69336">
        <property type="protein sequence ID" value="ACU69336"/>
        <property type="gene ID" value="Caci_0383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0383"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="GKQPELC"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="32603" checksum="4C9FF45D75568187" modified="2009-10-13" version="1">MQFHQLRYFIAVAETRHFTRAAEALHVTQPSLSQQIRALEHELGADLFLRARGNITLTDAGEALLPMARRILADADAARREVQELAELRRGHVRLGATPSLCTGLLPDVLRTYHRRYPGIQLLVQESGSHDLVRDLARGALDLALVVLPLPSPSPALTTEELLREDLVVVSAPNLPPPGDGRQVRIADLEHEQLIMFRHGYDLRDLTVAACRAQGFEPVFAIEGGEMDAVLGFARAGLGVAIVPSMVAQNVDPSLRVTPIAPPALHRTIALAHRTDVALPRAAQEFRRTLLERTTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVL8</accession>
    <name>C7PVL8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0422"/>
    <dbReference type="EnsemblBacteria" id="ACU69374">
        <property type="protein sequence ID" value="ACU69374"/>
        <property type="gene ID" value="Caci_0422"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0422"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023778_0_0_11"/>
    <dbReference type="OMA" id="TEANWAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="377"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="600" mass="61052" checksum="337816727E2576F7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW30</accession>
    <name>C7PW30_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-xylanase</fullName>
            <ecNumber evidence="4">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793007.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4414"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH10">
        <property type="family name" value="Glycoside Hydrolase Family 10"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73278">
        <property type="protein sequence ID" value="ACU73278"/>
        <property type="gene ID" value="Caci_4414"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4414"/>
    <dbReference type="eggNOG" id="COG3693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020161_3_0_11"/>
    <dbReference type="OMA" id="DSDSWIP"/>
    <dbReference type="OrthoDB" id="654705at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="PTHR31490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982611" description="Beta-xylanase" evidence="6">
        <location>
            <begin position="41"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="8">
        <location>
            <begin position="42"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="7">
        <location>
            <begin position="378"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="50568" checksum="7340F84EEC6E7E80" modified="2009-10-13" version="1" precursor="true">MHTDRTDRTDRTNRRLAAALAVIASCALAGSLALVRPAGAADTSLKQLSEAKGKYFGTALVQSNLSNSALVGVATSQFDMMTPGNEMKWDTTEPSNGSFNFGPGDTLVAFAQAHSMKVRGHNLVWHSQLPGWVSSLPSSQVQAAMETHITTEATHYKGEVYSWDVVNEPFNEDGTLRQDAFYNAMGTNYIADAIRTAHAADPNAKLYLNDYNIEGENAKSNAMYSLAQSLLAQGVPLGGIGLESHFILGQVPSTMQANMQRFAALGLDVAVTELDDRIQLPASSANLQQQASDYSAVIGDCLAVTRCVGVSQWGVGDADSWIPGTFSGYGAATMYDQNYQPKPAFNASIAALGGSSGSTSPSSSTPSTPPTTSSSSPGGGGSAACKVSDVVSAWNTGLTENITIANTGSAAVNGWKLTFTLASGQTVSNSWNATISPSSGQVTATNMSYNAAIAPGSSASFGFQATHTGNASAPSSFSLNGQVCTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA0</accession>
    <name>C7PWA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793077.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4485"/>
    <dbReference type="EnsemblBacteria" id="ACU73348">
        <property type="protein sequence ID" value="ACU73348"/>
        <property type="gene ID" value="Caci_4485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4485"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_11"/>
    <dbReference type="OMA" id="MLATDPP"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="421" mass="45930" checksum="1468AE75CE387F5D" modified="2009-10-13" version="1">MSDLPVLNTSDPAYAHDPYAVLAPIAEAGPVVRTMVDGLAVWLVTGYDEAVEALSSPRMSIDGIKNSGPEAREVFWAGAADRGLQSHMGRMDPPDHTRLRGLVQQTFTPRRVAALEPWIRGIVRERIEAFPSGDAEVDLMAAFALPVPIAVIAELLGIDVAQRSDFRHWADTILQASEQQEQVAAAAEAARRIMEMFAALVAQRRAAVGEVSLDISHEGTLIDGLIRAHDDGDALNERELLSLLFLLLGAGYETTANLIGNGMLTLLSDPARLAAVQADPTLLPVAIEEFLRLDPPVKVVFPRYPLADVELGGALIRAGEPVLVHFSAVSRDERRFNDPSVYRPGRGADRSEPSHLTFGYGLHHCLGAPLARLEARIAFDELLRTYPDIELVGPVEKLRREHSRLFRGLSALPVRLGERAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWM6</accession>
    <name>C7PWM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6455"/>
    <dbReference type="EnsemblBacteria" id="ACU75306">
        <property type="protein sequence ID" value="ACU75306"/>
        <property type="gene ID" value="Caci_6455"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6455"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_11"/>
    <dbReference type="OMA" id="LDRHEHG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="148"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="27427" checksum="CEC60BE0492911A1" modified="2009-10-13" version="1">MFHAHIVDYAYPPHCHDTWTVLIVDAGAIRYDLDTRHCGASRETVAILPPGVIHDGRPDDRAREGFWKRNIYLNASMLPTGLTGAAVDKTNLHDPFLRAALVGLHESLTIREEPLDGEARLAMIAERIAAHLLTRRPRLAAPETSIAHTLRQLLDEHLTEPITLQQAARSLDRSVPHLIRSFRQAFAISPHAYVIGRRVEAARGMLLRGAKPAAVAVDVGFYDQAHFTRHFKKHTSVSPAKYAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX03</accession>
    <name>C7PX03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8437"/>
    <dbReference type="EnsemblBacteria" id="ACU77260">
        <property type="protein sequence ID" value="ACU77260"/>
        <property type="gene ID" value="Caci_8437"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8437"/>
    <dbReference type="eggNOG" id="ENOG5033TIB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1080500_0_0_11"/>
    <dbReference type="OMA" id="MAPFRID"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="28968" checksum="218E52A4EAE1F2CE" modified="2009-10-13" version="1">MSKYRVNVCLPPSALTDVEGALAEAMAPFDMNRGESFDPDATWDWYRVDAGRQRFAVQPRHDGDPRLIHADPVIVGTPHEPLRCDGGPRGLLDFDACRRAARAEARTYWQAQHRDFERLVADHPPAEPLTAFLARHAADPEGYPRTEAVADHHAQPLIKALNHKSVFERYPNLGAWVLGPDTDPITIYRRDAEHSFELAETWAVARAALLTLEGEWIGIKPYSDDADEESDTFARRSTAYLEELDEDCLVVRLLCHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX10</accession>
    <name>C7PX10_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA topoisomerase 1</fullName>
            <ecNumber evidence="8">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">topA</name>
        <name evidence="11" type="ordered locus">Caci_8444</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796992.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8444"/>
    <dbReference type="EnsemblBacteria" id="ACU77267">
        <property type="protein sequence ID" value="ACU77267"/>
        <property type="gene ID" value="Caci_8444"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8444"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1754">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_3_2_11"/>
    <dbReference type="OMA" id="YAQPKQR"/>
    <dbReference type="OrthoDB" id="223233at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="10">
        <location>
            <begin position="14"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="8">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="828"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="891"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU77267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="944" mass="102682" checksum="AC32E327582E5CBB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF2</accession>
    <name>C7PXF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UBA/THIF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784798.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0566"/>
    <dbReference type="EnsemblBacteria" id="ACU69503">
        <property type="protein sequence ID" value="ACU69503"/>
        <property type="gene ID" value="Caci_0566"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0566"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_473839_0_0_11"/>
    <dbReference type="OMA" id="GSTHYEE"/>
    <dbReference type="OrthoDB" id="338532at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="PTHR43267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="2">
        <location>
            <begin position="387"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="674" mass="73296" checksum="380F488ECE888B77" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXH4</accession>
    <name>C7PXH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2509"/>
    <dbReference type="ESTHER" id="catad-c7pxh4">
        <property type="family name" value="Duf_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71427">
        <property type="protein sequence ID" value="ACU71427"/>
        <property type="gene ID" value="Caci_2509"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2509"/>
    <dbReference type="eggNOG" id="COG4099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025057_2_1_11"/>
    <dbReference type="OMA" id="THSAYWD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010427">
        <property type="entry name" value="DUF1023"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06259">
        <property type="entry name" value="Abhydrolase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="52766" checksum="BDD6739418A447BC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT9</accession>
    <name>C7PXT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793128.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4536"/>
    <dbReference type="EnsemblBacteria" id="ACU73399">
        <property type="protein sequence ID" value="ACU73399"/>
        <property type="gene ID" value="Caci_4536"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4536"/>
    <dbReference type="HOGENOM" id="CLU_1438694_0_0_11"/>
    <dbReference type="OrthoDB" id="1779215at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="19883" checksum="145CDABFE7102DDE" modified="2009-10-13" version="1">MMKRNDALVLGSAVTCQDDARAELSGLVIDSTTLRLSSIVVGGTVEPARLVPFELISGLDRDTTRISCTAASIQGLPPAETGKVLDVTENTGGWGLLSLIYATDSLPQTYLRARERVLASDGAVGRVHGCTIDVRKFPGQLTALLVNVGDAVEDRVIAAPTRAVTSMKGLVVLDMTKHTARALPRFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ4</accession>
    <name>C7PXZ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73454">
        <property type="protein sequence ID" value="ACU73454"/>
        <property type="gene ID" value="Caci_4592"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4592"/>
    <dbReference type="HOGENOM" id="CLU_3286805_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="40" mass="4717" checksum="E0E191A3027AED4D" modified="2009-10-13" version="1">MVNTDFLQDDDVDNEAPYRTFGLGLRARLQERVGIRREHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY47</accession>
    <name>C7PY47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4646"/>
    <dbReference type="EnsemblBacteria" id="ACU73507">
        <property type="protein sequence ID" value="ACU73507"/>
        <property type="gene ID" value="Caci_4646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4646"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_1_11"/>
    <dbReference type="OMA" id="NGMIGRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="15208" checksum="AF0B37BBF16DB973" modified="2009-10-13" version="1">MQDSTDMEMASAIGPCASIPADQMAFIRQVLDRVGDKWSMLIIAVLADSPLRYTDLHRQIPGISQRMLTHTLRHLHEDGLLTRTPHAEVPPRVEYALTPLSHGLHEIVTQLIHWASTHHDEIRANRSSTGTSSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM9</accession>
    <name>C7PYM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797076.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8528"/>
    <dbReference type="EnsemblBacteria" id="ACU77351">
        <property type="protein sequence ID" value="ACU77351"/>
        <property type="gene ID" value="Caci_8528"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8528"/>
    <dbReference type="HOGENOM" id="CLU_142297_2_1_11"/>
    <dbReference type="OrthoDB" id="1929443at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="9857" checksum="5253ECD86A13ED76" modified="2009-10-13" version="1">MTGGGFTVVPSEVQTNGGEFAAVADQVRAVQTTLLAKLNAEGACWGNDEAGAQVAKTYVEPAMKALQQMDDVDGGVSAMAEATASWGKSYQSVENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZN9</accession>
    <name>C7PZN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793283.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4693"/>
    <dbReference type="CAZy" id="GH4">
        <property type="family name" value="Glycoside Hydrolase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73554">
        <property type="protein sequence ID" value="ACU73554"/>
        <property type="gene ID" value="Caci_4693"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4693"/>
    <dbReference type="eggNOG" id="COG1486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045951_1_1_11"/>
    <dbReference type="OMA" id="YVPWYLH"/>
    <dbReference type="OrthoDB" id="277080at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001088">
        <property type="entry name" value="Glyco_hydro_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022616">
        <property type="entry name" value="Glyco_hydro_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32092">
        <property type="entry name" value="PTHR32092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02056">
        <property type="entry name" value="Glyco_hydro_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11975">
        <property type="entry name" value="Glyco_hydro_4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00732">
        <property type="entry name" value="GLHYDRLASE4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_4C" evidence="7">
        <location>
            <begin position="195"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="443" mass="47534" checksum="86303B7BE6B5AE18" modified="2009-10-13" version="1">MIRIAFVGAGSVVFTRQLLHDILSYPELSGAAIALHDIDPERLQVAAALADHAARTLGAEVSVTATTDRRAALAGADAVVNMIAVGGHQATVTDFEIPAAAGLRQTIGDTLGVGGIFRALRTFPVLRSLAQDMAEVCPDAWLLNYTNPMAMNIQYLSTIAPKLKVAGLCHSVYWTVRGLCDIIGIPHDDVDVLSAGVNHQAWILRWQHQGRDLYPALDAAIAASPDLARRVRVDMYQRLGYYPTETSEHSSEYVPWYLGHDTEITRLRIPVGDYIDISAENLAEYRELRKVITDGGDPANGWESDAAEYAPQVIHSLATGTPRTIQVTTPNTGLISNLPEAAAVEVPATLDRLGIHPHHVGALPPQLAAPNRHFLNVVDLVVAAAVEGDPRHIRHAAMADPATAATLTVDQIWNLCDAMVTAHGDALPEPLRRSPLAARGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZQ4</accession>
    <name>C7PZQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793298.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4708"/>
    <dbReference type="EnsemblBacteria" id="ACU73569">
        <property type="protein sequence ID" value="ACU73569"/>
        <property type="gene ID" value="Caci_4708"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4708"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_16_11"/>
    <dbReference type="OMA" id="ALARMIC"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="70"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="25454" checksum="832B22518E2D5FD6" modified="2009-10-13" version="1" precursor="true">MDPSLVALLSVPSAGASGFLAGVAAMRRRLRRAAGEAAHARWLADHDALTGLPNRHAARHHYQHAALAGRPPAAALLDLDDFKTVNDTWGHQVGDAHLVAVGERLAAACRDVGARAFRLGGDEFVLLLPSTDAATVVRDVRAIVCALGAPQYLKLDESRTVTLVPSASAGIAVPANEDAFSDVLRCADVALYHAKRYGAAPHLYTPDMRHPWSHRYKAMDEGHLGTARVSGLVAEQATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZU0</accession>
    <name>C7PZU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793334.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4744"/>
    <dbReference type="EnsemblBacteria" id="ACU73605">
        <property type="protein sequence ID" value="ACU73605"/>
        <property type="gene ID" value="Caci_4744"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4744"/>
    <dbReference type="eggNOG" id="COG2320">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112485_0_0_11"/>
    <dbReference type="OMA" id="FREPHDG"/>
    <dbReference type="OrthoDB" id="1551670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019646">
        <property type="entry name" value="Aminoglyc_AdlTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10706">
        <property type="entry name" value="Aminoglyc_resit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="25171" checksum="E1F3D6D125AE8F15" modified="2009-10-13" version="1">MPEDHDEERALEIPGARPLSPADIAALDDQWARAWTPAEVARRLEGVDLPWYVAGGWALDLFRGRQTRRHGDLEIGVPAARFGEISDRFPALVFGGVGQNRLWEIATPEVLAATHQTWLRDPATGDYLLDVFREPHDGTTWICRHRRTIRLPYEEIICHTPDGIPYLTPELVLLFKAKHVRPKDQGDFEGVAPELSPAQRARLAELIGQVYPEHPWLAELDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZW3</accession>
    <name>C7PZW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4767</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793357.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4767"/>
    <dbReference type="EnsemblBacteria" id="ACU73628">
        <property type="protein sequence ID" value="ACU73628"/>
        <property type="gene ID" value="Caci_4767"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4767"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075533_0_0_11"/>
    <dbReference type="OMA" id="CEEWEAN"/>
    <dbReference type="OrthoDB" id="1400891at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="22007" checksum="1EEDEB63438791BD" modified="2009-10-13" version="1">MAAHMSPDQAAAEVPALPGWSVQDTYAHITGISADILAGVPGNPHDPGWTAGHLSTRRGHSLAEICEEWEANGPGVEAALDDPARRRSVSAVLDAFHHGHDIRGALGRTEERHTPQAAFATALTIKIRSGPWAEAGNPPIEFATGSGGWRLGAPDAAPVAALSTSDFELSRLLIGRRSRAQMLAAGWSGDPEPIVDLLPAFGPPVTDLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0E7</accession>
    <name>C7Q0E7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797204.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8665"/>
    <dbReference type="EnsemblBacteria" id="ACU77480">
        <property type="protein sequence ID" value="ACU77480"/>
        <property type="gene ID" value="Caci_8665"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8665"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_1_1_11"/>
    <dbReference type="OMA" id="PAAEWCT"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="13406" checksum="EC7CDC6A999192D3" modified="2009-10-13" version="1">MKFLISMHINPAVLDALTEEEMAGIGEGHSRFMQALKDSGEFIMTQALVDPSQAAVVRVRNGQPVVTDGPFLEAKEYLGGFYLVDVQNKERAIELAAQIPDAAIEGLGLEVRQIMFSDGQLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0M9</accession>
    <name>C7Q0M9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784952.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0722"/>
    <dbReference type="EnsemblBacteria" id="ACU69657">
        <property type="protein sequence ID" value="ACU69657"/>
        <property type="gene ID" value="Caci_0722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0722"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_11"/>
    <dbReference type="OMA" id="MAMFYAN"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="7"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="363" mass="37275" checksum="C1422ABB7A3CD042" modified="2009-10-13" version="1">MVTPWAVCVGESMAALLPDVPGPLDGVESFAVSAGGAESNVACALRALGVPSAWISRVGDDGFGRRLVGEVTARGVDTSGVAVDPLRPTGLYLKETGGSTRDGDLGTGRSKLHYYRAGSAASAMSAATLRDPAVERLVDGARLVHLTGITPALSETCLDMVRALLDAPRGQRLVSFDLNLRPVLWRDRDAGVLREFVNAADVALLGADEAEIAFGTGDPAKLRALFPGPTTIVVKDAERVVTALTAKGAVSEPALTVDVVEPTGAGDAFAAGYLAGTLHGFDERRRLRLGHLAAASALVAQGDVGELGDLSRLADADAGGSAGAAEDDGQWSAATVAALLDAPEEQWRATRISADGIAFGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0R4</accession>
    <name>C7Q0R4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784987.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0757"/>
    <dbReference type="EnsemblBacteria" id="ACU69692">
        <property type="protein sequence ID" value="ACU69692"/>
        <property type="gene ID" value="Caci_0757"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0757"/>
    <dbReference type="HOGENOM" id="CLU_1425653_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="18703" checksum="C2B918E71B17427C" modified="2009-10-13" version="1">MDVSGAAEVGVSVVVVLAGLVGLLGLVAAARFGTESPRGRTLLLFGLGGAGVVVGLIGSMIQGYTVRVGGSGPRLLDAGDPASAGDGGSGGFAFPFGSLIGLALLTALLLLGGALLRAPRAVGAASGGWLLVVAALTFGVGSGGDIILPNDSAAQIFVYGGLVIAFGIAVLVYQWNLNDRLADKVVSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q108</accession>
    <name>C7Q108_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ccyl-CoA dehydrogenase type 2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2770"/>
    <dbReference type="EnsemblBacteria" id="ACU71683">
        <property type="protein sequence ID" value="ACU71683"/>
        <property type="gene ID" value="Caci_2770"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2770"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_2_11"/>
    <dbReference type="OMA" id="IYTDVEI"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013107">
        <property type="entry name" value="Acyl-CoA_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08028">
        <property type="entry name" value="Acyl-CoA_dh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="3">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="2">
        <location>
            <begin position="136"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_2" evidence="4">
        <location>
            <begin position="256"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="42909" checksum="DB080D4B406335B0" modified="2009-10-13" version="1">MTTTTTDPAPIPPAVELIPPAFDQLPEVTAFLAAHAEEHDRQASFPFDGVERVHRAGLLTATVGERHGGAGVRLAGTVRILRALGAGDPSVALVSAMTLFTHALQDSNPTWPQEYYRRLLAESSGAPALVNALRVEPDLGTPARGGLPATTARADGGDWVLTGRKIFSTGAPGLRWLAVWARTDEEPPRVGSFLVPADTAGLSVEPTWDHLGLRASGSHDVILDRVRIPREATAGLADPVADPRRDPALIAWNNLGLTALYLGVAEAARDWLIGFLHERTPSALGRPLATLPRFQAEVGEIEAALAGALTLVEALAERVDAGDRRAAETSGAAKLIGTRAAIGAVERAVALIGNNALTRRNPLERHLRDVLCSRVHTPQDDTITASLGAAALARPTDDPAKNRPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1B2</accession>
    <name>C7Q1B2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gcvP</name>
        <name evidence="10" type="ordered locus">Caci_4780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4780"/>
    <dbReference type="EnsemblBacteria" id="ACU73641">
        <property type="protein sequence ID" value="ACU73641"/>
        <property type="gene ID" value="Caci_4780"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4780"/>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_3_2_11"/>
    <dbReference type="OMA" id="CVPMSEY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU73641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1029" mass="108351" checksum="40CB0C89E9F42CF7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C1</accession>
    <name>C7Q1C1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4789"/>
    <dbReference type="EnsemblBacteria" id="ACU73650">
        <property type="protein sequence ID" value="ACU73650"/>
        <property type="gene ID" value="Caci_4789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4789"/>
    <dbReference type="eggNOG" id="ENOG502ZB65">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_876924_0_0_11"/>
    <dbReference type="OMA" id="GHLYMED"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="37404" checksum="461C1AA1AA68D876" modified="2009-10-13" version="1">MTATAQSAPLTPVFQELSQGTTVQNLPLSHLSVEVGHFYMEDLENGEDPIRAQFERVRPWLAAAEASVVCGTEKPRVSTCFLIDDYFQRWPDAKDIIEKLLRLSADAGVRIDYFARESSCAVRADGTRIAELVARRLLQEPEPEITTGSRPPTVRSGWLANGKPAREGKVLSAMRGHAWEPAVEFSKLNHSIFLDVELWRDFAEPGADDDVVLARRQYSCPFLAAVWQLIRLGLLRHDGAPALAVADQPAEWSNDWTVFPDIVKVNPAAKPFYAYRALSIMPSDFLGIEHAVRTIVDHFLVDPGVDESLQVRAAEKSVPLPSAVADRVSHHFLDGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y9</accession>
    <name>C7Q1Y9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV secretory pathway VirB4 protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6849"/>
    <dbReference type="EnsemblBacteria" id="ACU75690">
        <property type="protein sequence ID" value="ACU75690"/>
        <property type="gene ID" value="Caci_6849"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6849"/>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009097_4_1_11"/>
    <dbReference type="OMA" id="GENHLPF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981379" evidence="1">
        <location>
            <begin position="24"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="608" mass="64329" checksum="C7B7D0EB14455A41" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q231</accession>
    <name>C7Q231_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797292.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8753"/>
    <dbReference type="EnsemblBacteria" id="ACU77568">
        <property type="protein sequence ID" value="ACU77568"/>
        <property type="gene ID" value="Caci_8753"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8753"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_2_11"/>
    <dbReference type="OMA" id="LDCEKPV"/>
    <dbReference type="OrthoDB" id="1275789at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="28809" checksum="56AC1390AA64E0FD" modified="2009-10-13" version="1">MPEVQERPLDETVRHSLSGGVAWITLDRPEALNAITADHRDRLIALLRQASADPQTRVVVLTATGRGFCTGADLRPRPGAAPAAEPRPGDVARTIRDGAQALVAAVLDCEKPVIGAVNGIAAGIGAHLALACDLVIAAESAKFIEVFARRGLVPDGGGAHLLTRLVGVHKAKELMFFADDVPAAEALALGLVNRVVPDADLEKAARAWAERLAVGPTRALALAKNLVNRALEVDRATAFREEADAVELNMATHDGQEGVRAFVERRAPEFTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q257</accession>
    <name>C7Q257_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797318.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8779"/>
    <dbReference type="EnsemblBacteria" id="ACU77594">
        <property type="protein sequence ID" value="ACU77594"/>
        <property type="gene ID" value="Caci_8779"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8779"/>
    <dbReference type="eggNOG" id="ENOG50348WP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735074_0_0_11"/>
    <dbReference type="OMA" id="ATCETPK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982801" evidence="3">
        <location>
            <begin position="36"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="36270" checksum="7518FDAB85F59DC5" modified="2009-10-13" version="1" precursor="true">MPSPRGRRRRASLLAASAAALAVTAFGALPGAASAASAPASSPASSGTATAVAGQVHLDVKLLQGVLGGLHITGPNGLDIPLADLSLGEADAPNASGDSANFTNSVVRLRDNLISTLHLPGPEANLIDADAVSGTARVINGPGGYTQAYATVANLRLFLPLLNLPGSSAANGILKVDLVSAQATCVPGQKPTASAKMPTTINLLGRDIPVPLTGEVKLNVPGVANIDVQLAPTTTIGGTGASSAVEAQIKLNALNLASVSGGITLAKAACTTPAAATGSGSGSGTPTSQASSSHSAPGSGTTATTTAAVAAAPTSKGTSAAAAPAALNEKSTAALAHTGASGSLMPIAAIAVVLVLGGGALLVFLRKKAAGLPPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2F7</accession>
    <name>C7Q2F7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease RNase T and DNA polymerase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0866"/>
    <dbReference type="EnsemblBacteria" id="ACU69799">
        <property type="protein sequence ID" value="ACU69799"/>
        <property type="gene ID" value="Caci_0866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0866"/>
    <dbReference type="eggNOG" id="COG0847">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047806_7_3_11"/>
    <dbReference type="OMA" id="TREMVEP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="11"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="21582" checksum="B5323CE8A5457961" modified="2009-10-13" version="1">MSDLEDGLVNGYAVVDVETSGFQPPIAEILEVAIVHVDATGQVTGSWDSLLRPQGGVGATRVHGITREMVEPAPRFEDVGMELHGLLVDRVVVAHNLAFDAKFLVTQFARLGVHSPEIAGGACTLRTSQAMLPGPSYKLLDCCEAVGVELTDAHSALGDALATARLLGFFLQRGVNVGGMAVRPQAAVPQPRAELGDLFLSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2R1</accession>
    <name>C7Q2R1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2894"/>
    <dbReference type="EnsemblBacteria" id="ACU71803">
        <property type="protein sequence ID" value="ACU71803"/>
        <property type="gene ID" value="Caci_2894"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2894"/>
    <dbReference type="eggNOG" id="ENOG5033XI9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_690180_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="44141" checksum="D1B52179CBCB74B7" modified="2009-10-13" version="1">MTTDDQAFDLVAAEDLRLSYTSVRDWTMLHPELRGTPFQLYAIMRSLVIDKAGDQPSRRITLDQLCWLLPGVNGKPTSLTVVKDALRALDRLGLVTNPDSERLVTSTGDRGIKSRRRFQINDLPPDGFRGWRNAWDKLDSYREEWRTVAPKPPALGSAPVRNELDDGQDQRPKTDVGGIEQTLEGRNSDHRANQAEQDETPGHLDGRNSDRAGRNSAHGGRNSVRQLASDQPQRAPKKFLKEGSLSTVASAATDADPTRREREPVCDEEPDPADLIVKAWADAWTRTRSGPYPVRSPDAVRRNARRLLADGSNVDLLCMAAANMAERGWIDLDKHLERWIPPKTPGSPAADTSGRTAADCRWCDPFGWYEHANGDGARCNHPNDPPAGHPAATNTRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V3</accession>
    <name>C7Q2V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787138.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2936"/>
    <dbReference type="EnsemblBacteria" id="ACU71845">
        <property type="protein sequence ID" value="ACU71845"/>
        <property type="gene ID" value="Caci_2936"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2936"/>
    <dbReference type="HOGENOM" id="CLU_2421563_0_0_11"/>
    <dbReference type="OrthoDB" id="397330at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="9997" checksum="8C39D2080DE380FE" modified="2009-10-13" version="1">MTDADALVARYILDVWRAEHPEHAGCATLRVTNPDASDGAYGCDTGCSYYRFTAEAGCEHQAPEEFEFGDFGELADILEDLQRDYADGTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Y8</accession>
    <name>C7Q2Y8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2971"/>
    <dbReference type="EnsemblBacteria" id="ACU71880">
        <property type="protein sequence ID" value="ACU71880"/>
        <property type="gene ID" value="Caci_2971"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2971"/>
    <dbReference type="HOGENOM" id="CLU_2932782_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6498" checksum="57F678A4F11895D7" modified="2009-10-13" version="1" precursor="true">MAISEGGTEDAHDDDVGQRYADKVNAPLSQETLEALRVGLASEEHARFRRAQLRDGLSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q427</accession>
    <name>C7Q427_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0955</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785182.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0955"/>
    <dbReference type="EnsemblBacteria" id="ACU69887">
        <property type="protein sequence ID" value="ACU69887"/>
        <property type="gene ID" value="Caci_0955"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0955"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_5_1_11"/>
    <dbReference type="OMA" id="KDGIAHS"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="618"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="651"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="200"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="709" mass="73466" checksum="66E911D81B903216" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B4</accession>
    <name>C7Q4B4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1048"/>
    <dbReference type="EnsemblBacteria" id="ACU69974">
        <property type="protein sequence ID" value="ACU69974"/>
        <property type="gene ID" value="Caci_1048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1048"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_5_2_11"/>
    <dbReference type="OMA" id="HPWAPAL"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24661" checksum="DEFCC7149AF52CB2" modified="2009-10-13" version="1">MSAEAPAGTEPRTPLSRDRVLRAAVDIADKGGIASLTMRRLGETVGAEAMSLYYHVANKEALLDGVADVMIAEIVDAVADIPAPPDAAAWKGVMRSRILTAREVLLRHPWAPGVLQSRTAASPAVLSYIDTTLGIMVAGGFTYDQAHHAMHALGSRAFGFAQELFNPAGDPGEEPHPEVLAGIASQFPHLAAMIVDAVHNTPENTLGWCDDQTEFEFGLDLLLNGLDGMRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4N0</accession>
    <name>C7Q4N0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3090"/>
    <dbReference type="EnsemblBacteria" id="ACU71999">
        <property type="protein sequence ID" value="ACU71999"/>
        <property type="gene ID" value="Caci_3090"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3090"/>
    <dbReference type="eggNOG" id="COG1545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899964_0_0_11"/>
    <dbReference type="OMA" id="VPPRGAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022002">
        <property type="entry name" value="DUF35_Znr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12172">
        <property type="entry name" value="DUF35_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="80"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DUF35_N" evidence="2">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="239"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="36124" checksum="14B82BF1EBD060E6" modified="2009-10-13" version="1">MTTQNTQNAQTPDSDDRALHVLEFPGGYTRSTGPVIGRFLTGLRDGQLLGVRTPDGKVLVPPTEYDPQTAAALGDAEEDWVQVGPAGTVTSWTWVDAPRADHPMNRPFAWALIKPDGADTALLHAVDSGSKAAMATGMRVHPSWRAERSGSIKDIAFFAPGEGPAEVPALASEAALEPVSVVTLPHRLEYRLRPGTVWNHFIDGMAEGQIRATRCPACGKVYVPPRGACPADGLPATEWVDLPDTGVLTTFAVNNVPAAGAPEVPFISGYVLLDGADIAMLALVSDVPWQEVRIGMRVRAVWVPDAERTRSVKNLKWFAPTGEPDVPFERFEEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5M3</accession>
    <name>C7Q5M3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0225 protein Caci_9021</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_9021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0225 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797558.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9021"/>
    <dbReference type="EnsemblBacteria" id="ACU77834">
        <property type="protein sequence ID" value="ACU77834"/>
        <property type="gene ID" value="Caci_9021"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9021"/>
    <dbReference type="eggNOG" id="COG3012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099590_2_0_11"/>
    <dbReference type="OMA" id="WLYVDGD"/>
    <dbReference type="OrthoDB" id="1472440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00612">
        <property type="entry name" value="UPF0225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023006">
        <property type="entry name" value="UPF0225"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14945" checksum="F7DDCD3C87C96608" modified="2009-10-13" version="1">MPRRERRGGNAKAIPTTCPCGAGKPYADCCGPLHSARTTATTAEQLMRSRYSAFAVQDAAYLEKTHHSSTRPASVEFEPKLRWTGLEILGTTGGTAFHTDGTVEFIAHYTESGRAGSMRENSSFVREDGNWVYLSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q621</accession>
    <name>C7Q621_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785412.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1193"/>
    <dbReference type="EnsemblBacteria" id="ACU70118">
        <property type="protein sequence ID" value="ACU70118"/>
        <property type="gene ID" value="Caci_1193"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1193"/>
    <dbReference type="eggNOG" id="COG4805">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018914_3_0_11"/>
    <dbReference type="OMA" id="GRMWWAV"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="559" mass="61681" checksum="864823162787C43E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q623</accession>
    <name>C7Q623_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1195"/>
    <dbReference type="EnsemblBacteria" id="ACU70120">
        <property type="protein sequence ID" value="ACU70120"/>
        <property type="gene ID" value="Caci_1195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1195"/>
    <dbReference type="eggNOG" id="COG4709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057658_0_0_11"/>
    <dbReference type="OMA" id="WWVARGW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="439" mass="45113" checksum="C111D44549539833" modified="2009-10-13" version="1">MSSQGFEDMDGGGLDGTGEAGGPGSRASETSSGARSGQTSGDQVAAYAAEVRAQLADLSDAESAELLEDLEDHLREVAAEGAGSLRERLGAPGAYARELRQAAGLPEPGEGSGSGSAGRGARSRPSVRVRVRQALVDAERRARGHRAGREVLDFLPSLRPAWWVLRGWAAVRLLEVMTTDVDPWHDFALVPQVGNSTVIGFLALAAAVPASVYAARRTVPDGWRRRAVGAGEGILVLFTIGMALSALSTQSNYGENASSVAFDQGGSLPGLVDNGKPISNLYVYDRAGKPLDGVLVYDQDGQPIQADVYAGGSILDNDGWIDGNGSLVANIFPQQMLQTQWDDSAGGAHYVVMPPPEVNIPQGLHRASAPQGAQQSPATPTTAPTTTPPTTPTTTPSTTSSTPGPQASSPTSATPTSGATGAQPTSALPSTPAPSGTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q698</accession>
    <name>C7Q698_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3197</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3197"/>
    <dbReference type="EnsemblBacteria" id="ACU72104">
        <property type="protein sequence ID" value="ACU72104"/>
        <property type="gene ID" value="Caci_3197"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3197"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028808_1_0_11"/>
    <dbReference type="OMA" id="LCIFWRA"/>
    <dbReference type="OrthoDB" id="1421296at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="31589" checksum="970069E244564FE6" modified="2009-10-13" version="1" precursor="true">MPTDSGLSWNPVTDIDQMWQLDSMVSAYRAGTIVAVLAAVVGWFMVLRRQTFAGHTVALAGFPGAAAAVFLGVSASWGYFGFCIGAGAVIAALARNGKGGMAEESALTGIVQSFTLACGMLFVALYKGFLNGVNSLLFGSFLGVTSGDIAVLAAVAAVVLIVMALIGRPLLFASVDPSVADARGVPSRMLGVLFLVVLGATTAEVSQITGSLLVFALLVMPAATAQRVTARPALSLVLSVLFALAVTWFGLGAAYFSPYPIGFWITTFAFGCYLLANVYGFFARRRGTGRRRVAEVAMTVLGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6C1</accession>
    <name>C7Q6C1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787420.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3220"/>
    <dbReference type="EnsemblBacteria" id="ACU72127">
        <property type="protein sequence ID" value="ACU72127"/>
        <property type="gene ID" value="Caci_3220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3220"/>
    <dbReference type="eggNOG" id="ENOG5033IUU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942833_0_0_11"/>
    <dbReference type="OrthoDB" id="1134589at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982835" evidence="1">
        <location>
            <begin position="28"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="31317" checksum="93DBEDE6CE9B1956" modified="2009-10-13" version="1" precursor="true">MRHRLWSWRIAVTAALLALLPLASASAASWTRLPAYQTWTLVTALERGQGVSTDGTYYYFSGTYSLDKATVNGINDVATNAAAIPSQLSSQYGSNHIGDTDYYGGYVVAPIEDGSAYQHPLLALFNASDLSYTGRYVQLPLNLMPGGVPWVAIDAAAGLVYTAPWNQSTADGSDHLVVYSLNALLTLPTGAALPVLRTVQLSPPLSRIQGAKMWHGRLWASADIDGDKSVWTIDPTTGATAWQFAQDVQPNDEVEGLVALDIGPSGGQLHILNVGSGWKSIFLYFQHYALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6G9</accession>
    <name>C7Q6G9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793733.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5145"/>
    <dbReference type="EnsemblBacteria" id="ACU74004">
        <property type="protein sequence ID" value="ACU74004"/>
        <property type="gene ID" value="Caci_5145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5145"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="FGSIGSW"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="279" mass="29097" checksum="2B7E6461B1302DF5" modified="2009-10-13" version="1">MARTWLITGASRGFGRGLAEAVLDSGDQVLATARRPEQLADLVTRYGALVRTAALDVTDVEAARAAVAAAVGEFGRLDVVVNNAGFANSGPIEEMAEADFRGQFEANFFGVVNVTRAALPVLRAQRSGVFVQFSSVGGRVGGTPGMGAYQSAKFAVEGFSEVLAAEVAPFGVKVVIVEPGAFRTDWQGSSMELHAVGADYESTVGAMNAYRAENSDNQPGDPVRAARVIIDVVGHDDPPRRLLLGAQAVTSALAAGEARAEETRKWADASAAADFPPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6J1</accession>
    <name>C7Q6J1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable potassium transport system protein kup</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">kup</name>
        <name evidence="13" type="ordered locus">Caci_5167</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transport of potassium into the cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HAK/KUP transporter (TC 2.A.72) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5167"/>
    <dbReference type="EnsemblBacteria" id="ACU74026">
        <property type="protein sequence ID" value="ACU74026"/>
        <property type="gene ID" value="Caci_5167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5167"/>
    <dbReference type="eggNOG" id="COG3158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008142_4_2_11"/>
    <dbReference type="OMA" id="AADQFEI"/>
    <dbReference type="OrthoDB" id="589903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01522">
        <property type="entry name" value="Kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023051">
        <property type="entry name" value="K+_uptake_low_affin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="PTHR30540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU74026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="655" mass="70004" checksum="74C5C8E9246C1E6C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T2</accession>
    <name>C7Q6T2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fumC</name>
        <name evidence="5" type="ordered locus">Caci_7115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795673.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7115"/>
    <dbReference type="EnsemblBacteria" id="ACU75945">
        <property type="protein sequence ID" value="ACU75945"/>
        <property type="gene ID" value="Caci_7115"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7115"/>
    <dbReference type="eggNOG" id="COG0114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_11"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="33"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="429"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="345"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="51544" checksum="0EC9409CD2BA2DAD" modified="2009-10-13" version="1">MTNPEQGQTPPEILDLPVGIDAGGIRRETDAMGAVDVPADRYWGAQTQRSLEHFTVGDDHMPPGIHHAYGYVKMAAALVNGEAGRLPRWMADLIARVAAEVIAGDLDEHFPLYVWQTGSGTQTNMNVNEVISNRAIQLAGGTLGSKAPVHPNDHVNLAQSSNDSFPTATHVAAVLALQNHVLPELRKLHTALDAKAREWADIPKTGRTHLQDAVPLTVGQEWSGYAAQIAAATDRLESALPGLYELAAGGTAVGTGLNAPPGFAERFAAELAELTGHPFVTAPNKFAALAGAEAMVAASAGLRGVAVPLLKIANDIRFLGSGPRNGLGELRLPENEPGSSIMPGKVNPTQCEATMMVCLRILADDTALATAAAMGNFELNTMRPLIASSFLHSAQILTDATRNLRVFCIEGVELDRERIDHDLGRSLMLVTALTPEIGYDRAAQIAHTADAEGTTLREAAVASGWLTAEEFDRIVDPRAMTGRGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Y7</accession>
    <name>C7Q6Y7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7171"/>
    <dbReference type="EnsemblBacteria" id="ACU76000">
        <property type="protein sequence ID" value="ACU76000"/>
        <property type="gene ID" value="Caci_7171"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7171"/>
    <dbReference type="HOGENOM" id="CLU_3326172_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="38" mass="4011" checksum="648429A4378A5B57" modified="2009-10-13" version="1">MNDVLSLAELVIDDETERGLFGTPSISCGQTSAVSDHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I8</accession>
    <name>C7Q7I8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3274</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787474.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3274"/>
    <dbReference type="EnsemblBacteria" id="ACU72181">
        <property type="protein sequence ID" value="ACU72181"/>
        <property type="gene ID" value="Caci_3274"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3274"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_0_11"/>
    <dbReference type="OMA" id="CWSAVHG"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="24445" checksum="1D95F274FFB09AB7" modified="2009-10-13" version="1">MSTDRSAAENPRSAPASRPPVRRPRGAVREGLIEAGLELARTGGPDAVVLREATRIVGVVPNAAYRHFADRDELLAAVCTAAMAELGARIAAAIARVPGDHGDPDGAFGRMGAVGTAYLEFARDEPGLFATAFAVPDQHPYVVASGARGADGSPLSQLQEVLDELVEVGLLDPRRREGVEVPVWSTVHGLAVLIGQGPLRVLPDGDVRALTERVLRFIAESLLAPGEKTISAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7J0</accession>
    <name>C7Q7J0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transmembrane anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3276"/>
    <dbReference type="EnsemblBacteria" id="ACU72183">
        <property type="protein sequence ID" value="ACU72183"/>
        <property type="gene ID" value="Caci_3276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3276"/>
    <dbReference type="eggNOG" id="COG5660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179277_0_3_11"/>
    <dbReference type="OMA" id="CATYLEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="zf-HC2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="80" mass="8991" checksum="1C98F63271F90BCD" modified="2009-10-13" version="1">MGTMDCATFVELVTDFLEGALPEAEEERFVEHLTLCDGCETYLEQFRRTIDTLGELPADSLSAEARAKLLTAFRGFRRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7P8</accession>
    <name>C7Q7P8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787534.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3334"/>
    <dbReference type="EnsemblBacteria" id="ACU72241">
        <property type="protein sequence ID" value="ACU72241"/>
        <property type="gene ID" value="Caci_3334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3334"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_3_0_11"/>
    <dbReference type="OMA" id="GVVWDFN"/>
    <dbReference type="OrthoDB" id="1567509at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982998" evidence="1">
        <location>
            <begin position="30"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="39035" checksum="A926167292152812" modified="2009-10-13" version="1" precursor="true">MNRRLTGIAATAVVLALSATACSSSKSSASGSSAAAGGAGKSAAKATTAADLGGMDALVAAAKKEGTLNVIALPKTWANYGAIMDAFTAKYGIKITDANPDGSSQDELNAIKQLAGKSSAPDVVDVGQAAATSGAAAGQFAPYQVATWSQIADAQKDSQGLWYNDYGGYIAIGYDADKVKNPPTTLKSLDDPQYKSQVALNGDPTKANAALSGVLAASLASGGSLDNAQPGIDYFAKLKSDGVFVPVAATQATIQSGTTPITIDWDYLQASAASDLKAKGVTWKVVVPSDGLFGGFYSQAISATAPHPAAARLWEEFLYSADGQNLWLKGMARPAELPALQKDGTADATALAALPAVTGTPQFATQDQMTAASKLVVAGWAKATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Y4</accession>
    <name>C7Q7Y4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5292"/>
    <dbReference type="EnsemblBacteria" id="ACU74151">
        <property type="protein sequence ID" value="ACU74151"/>
        <property type="gene ID" value="Caci_5292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5292"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_2_11"/>
    <dbReference type="OMA" id="RDEMTTV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="115" mass="12241" checksum="53337B235CA32E55" modified="2009-10-13" version="1">MEFSCTARRAAGRVVLTVAGDVDLAAYARFEAGLEQSWDGTTDLVIDCSAVTFLDSMGLRVLVRSRRRAADHGREVMLASPSRPVRRALELAGVTSLFPVAEPVSGAEHGPNPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B1</accession>
    <name>C7Q8B1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTPase Obg</fullName>
            <ecNumber evidence="6">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">obg</name>
        <name evidence="11" type="ordered locus">Caci_7270</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795827.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7270"/>
    <dbReference type="EnsemblBacteria" id="ACU76099">
        <property type="protein sequence ID" value="ACU76099"/>
        <property type="gene ID" value="Caci_7270"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7270"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_1_3_11"/>
    <dbReference type="OMA" id="VVFDWEP"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
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    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
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    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
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    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="10">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="160"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="9">
        <location>
            <begin position="360"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="449"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="294"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="323"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="500" mass="53240" checksum="A7511DDADD49E5E2" modified="2009-10-13" version="1">MATFVDRVKLHVTAGNGGHGCASVRREKFKPLGGPDGANGGRGGDIVLVVDPNTNSLLDYHFSPHRKATNGKPGGGDFQTGANGVDLVLPVPSGTVVKDAFGEVVADLVGGGTRFVVAHGGIGGLGNAALSTSKRKAPGFALLGEPGDDGEFTLELKSVADVALVGYPSAGKSSLIAAVSAAKPKIADYPFTTLVPNLGVVSAGESVYTIADVPGLIPGASDGKGLGHEFLRHIERCAVLVHVLDCATLESDRDPISDLDVIEAELRAYEDSRDESEWGIYGKLSDRPRLVVLNKTDIPEGQDLADIVRPELAARGLDVYEVSAVSRAGLRELSFALAKIVDTARANRVEPEPERIVIRPKAVDEIGFTITYDEAEDAYFVRGTKPERWVRQTDFNNEEAVGYLADRLNKLGVETELVKMGANEGDTVVIGDGPRAVVFDWQPSIPTGALGVTATGGRRGEDPRLHLHEERPTSRDAEYRKAHRRRADGTIDLFAPEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8G7</accession>
    <name>C7Q8G7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7326"/>
    <dbReference type="EnsemblBacteria" id="ACU76155">
        <property type="protein sequence ID" value="ACU76155"/>
        <property type="gene ID" value="Caci_7326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7326"/>
    <dbReference type="HOGENOM" id="CLU_2599577_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8051" checksum="221D7F000D3BF2C6" modified="2009-10-13" version="1">MNRSGGLFLRVLTVIAGLALVGIVLKLIGSILTPILPASFNAALSSGLAHLVTIVSPAIPAIGALAIIALVLWIITGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8I9</accession>
    <name>C7Q8I9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase BadF/BadG/BcrA/BcrD type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7350"/>
    <dbReference type="EnsemblBacteria" id="ACU76177">
        <property type="protein sequence ID" value="ACU76177"/>
        <property type="gene ID" value="Caci_7350"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7350"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016274_1_2_11"/>
    <dbReference type="OMA" id="NCVGMRP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="9"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="32295" checksum="603A197C0A67B865" modified="2009-10-13" version="1">MTRAAVLAIDGGNSKTEVALAAADGTVLACVQVGGFTPHLDGMAGAVSVAGQGVALIRAELGLAADEPLAELLAAYVAGADFPVEVEALTAEFAARGWAERTIVDNDSFALMRSGTSRPWGVAVVCGAGMNCVGIAPDGRHARFPAIGTVSGDWGGGPGIGETAHWFAVRAEDGRGAPTVLRKAVAEYFGCASMAELVESIHFGRIADDRFGELAPLVFEVAGLGDEVALSIVERLADEVCAFAFAAMGRLDLMDAEVEVVLGGGVLRARQPLLTAGIERRFAARAPKAVLTLTTDRPIQGAVLLGLDELARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q981</accession>
    <name>C7Q981_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3495"/>
    <dbReference type="EnsemblBacteria" id="ACU72401">
        <property type="protein sequence ID" value="ACU72401"/>
        <property type="gene ID" value="Caci_3495"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3495"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009095_0_0_11"/>
    <dbReference type="OMA" id="REPTWAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1166" mass="126240" checksum="AE6366576A99D25A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9N4</accession>
    <name>C7Q9N4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">APS reductase</shortName>
            <ecNumber evidence="3">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysH</name>
        <name evidence="5" type="ordered locus">Caci_7377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7377"/>
    <dbReference type="EnsemblBacteria" id="ACU76203">
        <property type="protein sequence ID" value="ACU76203"/>
        <property type="gene ID" value="Caci_7377"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7377"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044089_2_0_11"/>
    <dbReference type="OMA" id="PIARWTQ"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="60"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="26542" checksum="1BED846462C94E3B" modified="2009-10-13" version="1">MSADTTPAPAGPAATALVGRTDLRALAEQANAELENAPAGRIVEWAHATFGADLVVASSMADTHLVHLASTAAPGVDVAFLDTGYHFAETLGTRDAVAEVYPVRLLNITPLQTVAEQDAEYGPRLHERNPDQCCALRKVEPLERALKPYTAWINGMRREESPTRADIPVIGYDAKRDMVKISPLAAWTQDDLDAYIVDHGVLTNPLFMEGYTSIGCEPCTRKPLPGEDPRAGRWAGNAKTECGLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q7</accession>
    <name>C7Q9Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7400"/>
    <dbReference type="EnsemblBacteria" id="ACU76226">
        <property type="protein sequence ID" value="ACU76226"/>
        <property type="gene ID" value="Caci_7400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7400"/>
    <dbReference type="HOGENOM" id="CLU_398857_0_0_11"/>
    <dbReference type="OMA" id="YLARHCA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025447">
        <property type="entry name" value="DUF4192"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13830">
        <property type="entry name" value="DUF4192"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="690" mass="70315" checksum="0E78EB4C00F07FA1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9T0</accession>
    <name>C7Q9T0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Monooxygenase, FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795977.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7423"/>
    <dbReference type="EnsemblBacteria" id="ACU76249">
        <property type="protein sequence ID" value="ACU76249"/>
        <property type="gene ID" value="Caci_7423"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7423"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028028_2_0_11"/>
    <dbReference type="OMA" id="PEGWYRR"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="490" mass="53547" checksum="61DCE4D74C1A92AC" modified="2009-10-13" version="1">MGNHIGERAVVLGGSIAGMLAAVPLSQAYREVILIDRDDLTEPEPDRPAGVLTVRRAVPHGWQLQALLAKGQRVLEELFPGMTDELVSFGASRGDFNKNVRWYFDGRKIKQVRSDMIAVGPGRPLLENRIRARISALPNVSFRQHTDILGIVATPDRKRILGARIQSQQPGAEPETLLGDLVLDATGRGSRTPRWLTELGYPEVEEERVKMGLAYSTGNFLIDREDDLLGEDVASVPIGTPNLPRGAVYARMAGYHSITLTGLLGQKPPTDRAGFLAYAESLAIPDIAEVVRRAEFIHDPVPYNFPESRRRRFDKMASLPENYLIMGDAACIFNPIYAQGMTVAAVEATVLRDHLSHGKTPDPLKFQRDVVKRGTAIAWDVAGAGDFTHRGVTGNKGVKFAVGGWFVQKVTAAAEFDDKLSTAFMRTAGLIAPPTSLMRPDLMARALFGKKSAPVPDPGYTPVRTAKVADIADASDAARRTLRSDLRKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y2</accession>
    <name>C7Q9Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Limonene-12-epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796026.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7476"/>
    <dbReference type="EnsemblBacteria" id="ACU76301">
        <property type="protein sequence ID" value="ACU76301"/>
        <property type="gene ID" value="Caci_7476"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7476"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124277_1_1_11"/>
    <dbReference type="OMA" id="HELYAME"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15698" checksum="52FB29E6CBFC6D27" modified="2009-10-13" version="1">MTVTTLPTGTAHAETARAFFRLLSAKDIAAWADLWHPDAVISVPYPPAGFPTEIRGKAEIASGFHSLFANFATFTAHLTGVYPAADSDAVCVEYRNVAVLHDGTEYTNDNIAVFRFQDGLITEYHDYFDPRRFQVVVDALGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA60</accession>
    <name>C7QA60_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785752.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1537"/>
    <dbReference type="EnsemblBacteria" id="ACU70458">
        <property type="protein sequence ID" value="ACU70458"/>
        <property type="gene ID" value="Caci_1537"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1537"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_9_0_11"/>
    <dbReference type="OMA" id="HHVEVWV"/>
    <dbReference type="OrthoDB" id="1857145at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16118" checksum="9697DE16468D4DDC" modified="2009-10-13" version="1">MPPTGFHHVEIWVEDLRAVEASWAWLLGQLGWELYQNWPEGRSWRNGDAYLVVEQSSAVRPGLPYDRLRPGLNHVAVHAPDETTVDRIQAAGPAHGWEQLFADVYPHAGGPEHYAAYLADVAGFEVEVVAPSAAGTAQHGKSAADAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAA1</accession>
    <name>C7QAA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DEAD/H associated domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1578</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1578"/>
    <dbReference type="EnsemblBacteria" id="ACU70499">
        <property type="protein sequence ID" value="ACU70499"/>
        <property type="gene ID" value="Caci_1578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1578"/>
    <dbReference type="eggNOG" id="COG1201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002025_3_0_11"/>
    <dbReference type="OMA" id="LPFWHGD"/>
    <dbReference type="OrthoDB" id="35275at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="281"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1604" mass="171381" checksum="2537D100C6174AF1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD3</accession>
    <name>C7QAD3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3526"/>
    <dbReference type="EnsemblBacteria" id="ACU72432">
        <property type="protein sequence ID" value="ACU72432"/>
        <property type="gene ID" value="Caci_3526"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3526"/>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403197_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982671" evidence="1">
        <location>
            <begin position="42"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="277"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="682" mass="68306" checksum="7BCCCF47AEFB2E18" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG2</accession>
    <name>C7QAG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792190.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3556"/>
    <dbReference type="EnsemblBacteria" id="ACU72461">
        <property type="protein sequence ID" value="ACU72461"/>
        <property type="gene ID" value="Caci_3556"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3556"/>
    <dbReference type="eggNOG" id="COG3837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_6_2_11"/>
    <dbReference type="OMA" id="KNIPHSW"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18302" checksum="DE6C36F32917C4AC" modified="2009-10-13" version="1">MTAIPAFPSLPEKVVALADVDPIRWGGEEAARFLLTGQDTGGLYSYYEVSVPAGEGSIFHVHEDMDETFFVIEGEFDVKIDDTIHAAPQGVLVYGPRGRGHSFFNTWHQPSKMLCVTTPGGIEDFFTDLSTLMAEPAPPDWERMSGLAAKHRITAHRPLGGPHGGPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAP5</accession>
    <name>C7QAP5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74368">
        <property type="protein sequence ID" value="ACU74368"/>
        <property type="gene ID" value="Caci_5509"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5509"/>
    <dbReference type="HOGENOM" id="CLU_1193084_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24873" checksum="84CF56E688C2D367" modified="2009-10-13" version="1">MNSSEHSSIANLSLPPGAGDGFIRPPPRPPHSATAPPPERRATRNALGLDRPLGHPEYVGGLPRREVAVEHLEQRGRRSGLSRRSATRTSCAFATPLTSPTASAMGARPRRSSRPCVPGGPGPRQSRPSGHLNSHGRAVQHGGVHGGAGGHVRHPSCVHGYGLAGSTGPRSPHRGDRRFATRTRPRSGIRELHHRTGPWATHAILRRSLGGSARPHCDVHARYRSVRENSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ8</accession>
    <name>C7QAZ8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein Caci_5612</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794200.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5612"/>
    <dbReference type="EnsemblBacteria" id="ACU74471">
        <property type="protein sequence ID" value="ACU74471"/>
        <property type="gene ID" value="Caci_5612"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5612"/>
    <dbReference type="eggNOG" id="COG1660">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059558_0_0_11"/>
    <dbReference type="OMA" id="TVMSFGF"/>
    <dbReference type="OrthoDB" id="1603998at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="98"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="35802" checksum="09C69A19B085B4EA" modified="2009-10-13" version="1">MRANRPSGRDAQDEPDQAVQEPEGSEDAGNDAAQDGPHAPELVIVTGMSGAGRSTAAKIFEDLGWYVVDNLAPTLIAPMIDLVMRESRSTDRLAFVVDVRGRAFFDTLRSTLDELDSAGLNHRIVFLESEDDVLIRRYEGVRRPHPLQGEGRVTDGIERERELLRELRGEADLVIDTSARNVHELRTAIESAFGDPGEVPLRATVMSFGFKYGLPVDADLVADVRFLPNPHWVPELRPRTGQDPEVSGYVLSQHGAKEFLERYAEVLNIITEGYRREGKRYMTLAIGCTGGKHRSVAMSEQIAARLSAEGVDTQVVHRDMGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB41</accession>
    <name>C7QB41_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7507"/>
    <dbReference type="EnsemblBacteria" id="ACU76332">
        <property type="protein sequence ID" value="ACU76332"/>
        <property type="gene ID" value="Caci_7507"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7507"/>
    <dbReference type="eggNOG" id="COG3619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061825_2_0_11"/>
    <dbReference type="OMA" id="ARHIDLH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="237" mass="24224" checksum="A83EF3EE0A098094" modified="2009-10-13" version="1">MPASGLITTVKAALLRLSDRLYDDGAAKHGVLPAPLIVATLVTGVVDAVSYLALNHIFVANMTGNVVFLGFALAGAKGLTVWAPCLAIACFAAGAWAEPRLARRTAGDDQHRRLANAVAAHAVFVAVALLIAAAEDDGKTSTHAQLTAILAFGFGVQNAVVRKLAVPDLTTTVLTMTVTGIASDPFGKPTVRRLLSLGCIFAGALCGGLLVLHQSISAALGLALALLVVTAVLARAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB93</accession>
    <name>C7QB93_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796109.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7559"/>
    <dbReference type="EnsemblBacteria" id="ACU76384">
        <property type="protein sequence ID" value="ACU76384"/>
        <property type="gene ID" value="Caci_7559"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7559"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_11"/>
    <dbReference type="OMA" id="GIRRWPE"/>
    <dbReference type="OrthoDB" id="1033353at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="8"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33874" checksum="1B5B35D7C5BD57CE" modified="2009-10-13" version="1">MRYDSLLDSVGHTPLVGLPNLSPSPEVRLWAKLEDRNPTGSVKDRVALGLIESAEKDGRLKPGDTILEPTSGNTGIGLAMVAKLKGYKLICVMPENTSEERRQILRMYGAEIISSNAAGGSNEAVRVAKELAAEHPDWVMPYQYGNPANALAHYHGTGPELLADLPTITHFVAGLGTTGTLMGVGRYLREKKPDVQIVAAEPRYDELIYGLRNLDEGFVPELYDESVLTTRYSVGAHDALRRTRELLAAEGVFAGISTGCALHAALGIARKAAEAGQGADIAFIVADGGWKYLSTGAYEGTLDEAEDRIEGQLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH7</accession>
    <name>C7QBH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785848.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1633"/>
    <dbReference type="EnsemblBacteria" id="ACU70554">
        <property type="protein sequence ID" value="ACU70554"/>
        <property type="gene ID" value="Caci_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1633"/>
    <dbReference type="eggNOG" id="ENOG5032RNQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151863_0_0_11"/>
    <dbReference type="OMA" id="ASCFLVH"/>
    <dbReference type="OrthoDB" id="1959396at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025242">
        <property type="entry name" value="DUF4193"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13834">
        <property type="entry name" value="DUF4193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="10833" checksum="BAFC44A1215D1AEB" modified="2009-10-13" version="1">MATDYDTPRKTDDDLNEDSLEELKARRTDKAAGLADLDEGDNESLELPGADLSNEELSVRVLPRQADEFTCTSCFLVHHRSQLAREKGNEMTCKDCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBI6</accession>
    <name>C7QBI6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1642"/>
    <dbReference type="EnsemblBacteria" id="ACU70563">
        <property type="protein sequence ID" value="ACU70563"/>
        <property type="gene ID" value="Caci_1642"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1642"/>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046525_2_4_11"/>
    <dbReference type="OMA" id="RWTADQM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="136"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="219" mass="23275" checksum="4F1E2F441AA5B87F" modified="2009-10-13" version="1">MHVVIMGCGRVGSTLAHSLEDLGHTVAVIDQDPGAFRRLSPHFAGRRVTGAGFDRDTLAEAGIGDAGAFAAVSSGDNSNIIAARVARENFGVENVCARIYDPRRAEIYQRLGIPTVATVRWTADQMLRRLLPTGSTEIWRDPSGQVVLVEVHTAPGWMGHRIAKLEDATGTRVAFLTRLGDAVLPAADTVLQDGDLVQVMVNPADIARVEAAFAKGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCC1</accession>
    <name>C7QCC1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ordered locus">Caci_5711</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794298.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5711"/>
    <dbReference type="EnsemblBacteria" id="ACU74569">
        <property type="protein sequence ID" value="ACU74569"/>
        <property type="gene ID" value="Caci_5711"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5711"/>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034247_0_0_11"/>
    <dbReference type="OMA" id="RGPHDLI"/>
    <dbReference type="OrthoDB" id="1789381at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="28790" checksum="4B93BE22D92B3B34" modified="2009-10-13" version="1">MNVLAEIIEGVRLDLAERQEKISLDDLKARVARMDSARDGVELLRRGGAGGDGVKVIAEVKRSSPSKGALAAIADPAGLAADYEAGGATVISVLTEQRRFGGSLGDLDDVRKKVDIAVLRKDFIVTSYQLWEARAHGADLALLIVAALEQPALESLIERAASIGLTPLVEVHDEEEVRRALDAGARLVGVNARDLKTLEVRRDTFARLAPLVPDGVVRVAESGVRGPHDLIAYANAGADAVLVGESLVTGKDPRAAVADLVAAGAHPALRNGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCT2</accession>
    <name>C7QCT2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785936.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1721"/>
    <dbReference type="EnsemblBacteria" id="ACU70642">
        <property type="protein sequence ID" value="ACU70642"/>
        <property type="gene ID" value="Caci_1721"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1721"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="VFPHIRG"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="33194" checksum="EFC8FE0306E10902" modified="2009-10-13" version="1">MARTASPRAAEDPAGLGRAGAAAITAPALLVVAAFLVFPALWTLYLGTTNYRLTGFAARHPHGVGLQNYTNVVQDPGFHHSLWLTLEYVLLSAVVGQAALGFAIAWMLRDATGWLKRLIEALVLLAWILPSSVVAFLWVAMLDRDSGTLNALLHTPGTAWAIEHPMAVIIVFNIWRGTAFSMLLYSAALTSVPPSQLATARMFGANSWQQLRDVVFPHIRGHILTNLLLISLWTFNDFTPYQITAGGPNGKSQILPVYIYQTALFDGQMGLGAAISLLMLLINLIVALVYLRLLRERRREPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ0</accession>
    <name>C7QCZ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Uncharacterized N-acetyltransferase Caci_1779</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase Eis family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785994.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1779"/>
    <dbReference type="EnsemblBacteria" id="ACU70700">
        <property type="protein sequence ID" value="ACU70700"/>
        <property type="gene ID" value="Caci_1779"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1779"/>
    <dbReference type="eggNOG" id="COG4552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050659_0_0_11"/>
    <dbReference type="OMA" id="FLWVRIN"/>
    <dbReference type="OrthoDB" id="1497065at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01812">
        <property type="entry name" value="Eis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041380">
        <property type="entry name" value="Acetyltransf_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025559">
        <property type="entry name" value="Eis_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022902">
        <property type="entry name" value="NAcTrfase_Eis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17668">
        <property type="entry name" value="Acetyltransf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13530">
        <property type="entry name" value="SCP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_17" evidence="5">
        <location>
            <begin position="182"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="SCP2_2" evidence="4">
        <location>
            <begin position="309"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="3">
        <location>
            <begin position="85"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="3">
        <location>
            <begin position="93"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; via carboxylate" evidence="3">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="411" mass="44724" checksum="553B7C10782ACF59" modified="2009-10-13" version="1">MPLEITAVGDAGFDDFCDAVEVGMNRPGGRGHGPFQRGLFAADVAAGRAIGAHDGGRVVGTFGNYRNTLAVPGGAAVPVGAVTAVTVAPTHRRRGILTAMAATAFRQSADAGEPLSILIPAEWPIYGRFGYGHATDEACYTFQTDRCAPVRPLPGTVELAPAEEWIPEAEAVYGRLRATTPGAIERSAMWWRRETGLETRDGKPTDKEWLYALYRDDAGTARGAAYYKPEEGTWEGLVPDDTAEAYMIAEDYVARVRLLQFLWEQDWLATFTVDKCPVDDTWRHLMADPRRARQKQRYDVLWVRVLDTVAALQARTYEGEGRLVLAVTDPAGYAEGVYALEGGPAGASVRRTTQTPDLTLPVQTLGALYLGNHAATALSRVGEVTEERPGALALADRMFKTAIPPYCVTWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDA5</accession>
    <name>C7QDA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FMNH2-utilizing oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3796"/>
    <dbReference type="EnsemblBacteria" id="ACU72698">
        <property type="protein sequence ID" value="ACU72698"/>
        <property type="gene ID" value="Caci_3796"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3796"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_1_1_11"/>
    <dbReference type="OMA" id="REKLHYI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000337-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="47450" checksum="669F4390141ACC74" modified="2009-10-13" version="1">MPANAPLHLAIALNDAGWHPAAWREPDARPSELFSARYWADQVAEAERGLVDFVTIEDSLGVQSGDYHSADDRTDQVRGRLDAVLIAARVAAVTRTIGLVATGVVTHTEPFHLSKAIATLDYASTGRAGIRIQVTARGFEADLFGRRTFPPFRLEDFETPEVQALTAELFDEAVDYVEVLRRLWDSWEDDAEIRDAATGRFIDRHKLHYIDFEGAHFSVKGPSITPRPPQGQPLVTALGHATVPYRLIARAADVGFVTPRYADQAAEIVEEIRHEQELAGRAAERLHIFGDVLVFLDETEAAARDRRARLDAVAGSELTSDAHIFAGTPAQLADLLADWHRAGLSGFRLRPATVPHDLEQITRGLVPELQRRGLFRRSYEADTLRGLLGLERPANRYASAAVSTTVSPSVSPSVSASVSAGEPAAEAADSSFAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDB6</accession>
    <name>C7QDB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792438.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3808"/>
    <dbReference type="EnsemblBacteria" id="ACU72709">
        <property type="protein sequence ID" value="ACU72709"/>
        <property type="gene ID" value="Caci_3808"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3808"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_5_11"/>
    <dbReference type="OMA" id="MLPMGTW"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980860" evidence="1">
        <location>
            <begin position="33"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="427" mass="45491" checksum="5E93CF3513684E16" modified="2009-10-13" version="1" precursor="true">MDRRKFLTFCATAAAAAPLAACGSSKSSPAGAAAADSSPVELTVSVWSLASTPEFHALFDAFHQANPNITIKPVDILAADYPTKVTTMLAGGDSTDVITMKQVSDYSLYAARGQLKDLTSIATSGAAATLNGLDSYKTKDGKYYALPYRQDFWVLFYNKKLFTAAGKQAPDNLTWDQYSDLAKSVTTGSGGDKVYGTYHHIWRSVVQAISAAQTGGNLLGDDYSFFTDQYKMALGIQDAGATLDFATATTQKTGYATVFETSKAAMLPMGTWFIAKLLADKKSGDTDVDWAIAPMPQRPGGSTVTTFGSPTAFAVNKKAKHAAAAEKFVQFAAGPEGAKAITAIGVVPSLLSDQTRQDYFALTGMPTDDVSKKAFKPDKVVLEMPASDKSSKIDAILTEEHQLVMTKQKSIDAGIKEMGSRVKNEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD4</accession>
    <name>C7QDD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MOSC domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_3827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3827"/>
    <dbReference type="EnsemblBacteria" id="ACU72727">
        <property type="protein sequence ID" value="ACU72727"/>
        <property type="gene ID" value="Caci_3827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3827"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033218_0_0_11"/>
    <dbReference type="OMA" id="QPRVTCY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000951">
        <property type="entry name" value="Ph_dOase_redase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005163">
        <property type="entry name" value="YiiM-like_3-alpha_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03475">
        <property type="entry name" value="3-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00409">
        <property type="entry name" value="PHDIOXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="7">
        <location>
            <begin position="30"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="240"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="508"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="475"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU72727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="590" mass="62635" checksum="0E715899E42B23DB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDG9</accession>
    <name>C7QDG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792491.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3871"/>
    <dbReference type="EnsemblBacteria" id="ACU72762">
        <property type="protein sequence ID" value="ACU72762"/>
        <property type="gene ID" value="Caci_3871"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3871"/>
    <dbReference type="eggNOG" id="ENOG5033Y1B">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137407_0_0_11"/>
    <dbReference type="OrthoDB" id="1554007at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18730" checksum="6A898166A11EEB0F" modified="2009-10-13" version="1">MDFELDPPHGVGPLRIGISRAEADAALLLLRDADSLSQSDRPGQHIFRPSGLMISISCMRDRLEAIELARPEIHADTVRFRDVDLFTLPAREVVERLRQHTPVEPAEDDPASFVAPELLLSLWRPFEADDEPLEAQGHYFTTVLLARPGYYDTPAQAAERHRSGLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDL4</accession>
    <name>C7QDL4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794367.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5780"/>
    <dbReference type="EnsemblBacteria" id="ACU74638">
        <property type="protein sequence ID" value="ACU74638"/>
        <property type="gene ID" value="Caci_5780"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5780"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_11"/>
    <dbReference type="OMA" id="ERAWAMT"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="221"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="37116" checksum="F8C150784F2D54F5" modified="2009-10-13" version="1" precursor="true">MNSAWALVVSALLLAANAFFVAAEFALVTSKRHRLEAAAAEGSRAARVAVAGTRELSLMLAGTQLGITLCTLGLGALAEPAVAHLLDPVLSATGLPEGVSYGIAFAASLALVVFLHMVVGEMAPKSWSITHPERSAALVALPFRAFTQLVRWPLVALNGMTNGLLRLLKVEPQSELAEAHSPEDLRMLVRQSAEHGLIPAVQQRLLAQALRLQNTPLSEVMIAWTDAVTVPCDSTASAVEDLSRATGHSRFPVTGADGNPVGLVHVRDAVRATTAGLDPDVSDLRSTALTLRADQTGAEAVSVMRRYRSQLALVKSGAGGDEGAQDTDAVVGVVALEDLLEELIGEFQDETDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDT4</accession>
    <name>C7QDT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794437.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5850"/>
    <dbReference type="EnsemblBacteria" id="ACU74708">
        <property type="protein sequence ID" value="ACU74708"/>
        <property type="gene ID" value="Caci_5850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5850"/>
    <dbReference type="eggNOG" id="COG3553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2154681_0_0_11"/>
    <dbReference type="OMA" id="CSHASRM"/>
    <dbReference type="OrthoDB" id="1858344at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014543">
        <property type="entry name" value="UCP028291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09981">
        <property type="entry name" value="DUF2218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="11609" checksum="526B4364A0490473" modified="2009-10-13" version="1">MPTAEGHVPTDRASRYLQQLCSHASRMRHVGIGIGHAAHRGPSVEATSDSTGRITRGSARCDLTASPTALVLHVTADDEEQLRALQEAVTRTLERAGRRDGLKVVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE54</accession>
    <name>C7QE54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transglycosylase associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796367.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7818"/>
    <dbReference type="EnsemblBacteria" id="ACU76642">
        <property type="protein sequence ID" value="ACU76642"/>
        <property type="gene ID" value="Caci_7818"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7818"/>
    <dbReference type="HOGENOM" id="CLU_2435461_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="8989" checksum="3E4A7DE44870F3C1" modified="2009-10-13" version="1" precursor="true">MSFFTLLWLAALGLGIGALGRAVVKDGTPMATWMTAVVGVVGAVGGGSVIHAILGDGHTLVATLLGVALAALLVMAITSWQRTRGEGEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE86</accession>
    <name>C7QE86_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786071.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1857"/>
    <dbReference type="EnsemblBacteria" id="ACU70777">
        <property type="protein sequence ID" value="ACU70777"/>
        <property type="gene ID" value="Caci_1857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1857"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="PPYSLFW"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="15"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="36171" checksum="EEEF5D7EE8496E40" modified="2009-10-13" version="1">MEFRHLGRSGLIISEIAYGNWITHGSQVEEDAALACVRAALDAGITTFDTADVYAGTRAEAVMGRALTGERREGLEIFTKVFWPTGPGRNDRGLSRKHIMESINGSLKRLQTDYVDLYQAHRYDYSTPLEETMAAFADVVHSGKALYIGVSEWKASEIRAAKALADELKVQLISNQPQYSMLWRVIEAEVVPTSEELGLGQIVWSPIAQGILTGKYLPGAELPAGSRATDENSGANVMRDLVANRDLLEAVQQLKPIAEAVDLSMAQLAVAWVLQNPNVSAAIIGASRPEQVAENVKAAGVKLPEDVMKQIDEVLGAHVVRDPARTVSPATRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER1</accession>
    <name>C7QER1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792560.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72831">
        <property type="protein sequence ID" value="ACU72831"/>
        <property type="gene ID" value="Caci_3948"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3948"/>
    <dbReference type="HOGENOM" id="CLU_2697837_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="7788" checksum="7C5538F6FA5CAA20" modified="2009-10-13" version="1">MEAGDLHDPGHLLQAEHGDDAEWFTPQRAADEMREAVQRLRHQLHAGPAPLPAAAPGEQFPPGDAGEQDGSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL5</accession>
    <name>C7QFL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_7969</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7969"/>
    <dbReference type="EnsemblBacteria" id="ACU76792">
        <property type="protein sequence ID" value="ACU76792"/>
        <property type="gene ID" value="Caci_7969"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7969"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_11"/>
    <dbReference type="OMA" id="DLMIPRV"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="12">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="214"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="276"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="555" mass="58455" checksum="30F8DA1EC4DBEC2D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFP4</accession>
    <name>C7QFP4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784278.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0028"/>
    <dbReference type="EnsemblBacteria" id="ACU68983">
        <property type="protein sequence ID" value="ACU68983"/>
        <property type="gene ID" value="Caci_0028"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0028"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_36_3_11"/>
    <dbReference type="OMA" id="WIACATS"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU68983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="17057" checksum="4A8D844C72DF137D" modified="2009-10-13" version="1">MTDIEIRPATLDDLDGLSHDSAELFAEDGLARDRLRDPDWPRDNNRAWCAGLIAAPDALVLVATEEGTVVGHLIGTFSPASSMWTAARAELVSTHVAPSYRGQGIGGRMVEDFIAWGKDRGAARLHVSAYTANSAAIRFYQRFGFVPLSIELTLDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU3</accession>
    <name>C7QFU3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2000"/>
    <dbReference type="EnsemblBacteria" id="ACU70920">
        <property type="protein sequence ID" value="ACU70920"/>
        <property type="gene ID" value="Caci_2000"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2000"/>
    <dbReference type="HOGENOM" id="CLU_3041630_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="6000" checksum="7C08F8E3445D0141" modified="2009-10-13" version="1">MPKDIDALVALNRDPGLLLDDRHVVQCLPTDDSLDLLADIPNGYFTDDWSPFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG71</accession>
    <name>C7QG71_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792645.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4051"/>
    <dbReference type="EnsemblBacteria" id="ACU72916">
        <property type="protein sequence ID" value="ACU72916"/>
        <property type="gene ID" value="Caci_4051"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4051"/>
    <dbReference type="eggNOG" id="COG3093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007145_0_0_11"/>
    <dbReference type="OMA" id="PCPFDEL"/>
    <dbReference type="OrthoDB" id="34961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1269" mass="138984" checksum="5D10213B482B69AD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ3</accession>
    <name>C7QGJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA alkylation repair enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794602.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6016"/>
    <dbReference type="EnsemblBacteria" id="ACU74873">
        <property type="protein sequence ID" value="ACU74873"/>
        <property type="gene ID" value="Caci_6016"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6016"/>
    <dbReference type="eggNOG" id="COG4912">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079880_1_1_11"/>
    <dbReference type="OMA" id="YFVCDYL"/>
    <dbReference type="OrthoDB" id="1933111at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="29109" checksum="8B388B50DEFB8B63" modified="2009-10-13" version="1">MTDATTTPIPALVSGLDRDLDGLGTAARATYDQQYHKSEFAHMGVPVPDLRKLVKDMYKEIGGRRATHDDVTGLAAALWDTDIYERRLAAVFVLAQGVRLLTAADLQDLTLMLRDAPMWSLVDPLSGDVAGKIVLRDREGTSRTLDLWAGDGDFWLRRASLLALIPAIREGKPDLVRFTRYADPMVEEREFFIRKAIGWVLREIAYKDPTWVAAWVTTRLDRLAGVTFREAVRRLPEDASVRLTAEYKAAGGGRSRARVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM9</accession>
    <name>C7QGM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMP-30/Gluconolaconase/LRE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794638.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6052"/>
    <dbReference type="EnsemblBacteria" id="ACU74909">
        <property type="protein sequence ID" value="ACU74909"/>
        <property type="gene ID" value="Caci_6052"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6052"/>
    <dbReference type="eggNOG" id="COG3386">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023267_0_1_11"/>
    <dbReference type="OMA" id="WGRRHVR"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="60"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="36124" checksum="7959C09392041478" modified="2009-10-13" version="1">MAQRSKMAAVRWTPPPNPQPVRRRGDVRTLPEVRRIALPGAGPEHIAVDTAGNLLTGLADGRILRVTPEGEVRAVTTTGGRPLGLEMLGEDALVVCDAYRGLLEVQLSNGTVGVLAAKVAGEPLTFCSNAAVAADGSIYFTQSSRHFNIDAYRGDLFEHSATGRLFRYRDGGVEVVADGFAFANGVVLVEDGAAAIVAETGGYCLTRVQLEGAETGRTSPFGAPLAGFPDNLTSDADGLIWAAMVSPRDPALDWLLPRNPRLRSLVWATPERLQPAEKDVAWAIAFDASGEKVRELRGWGVGYKSVTSARRSGETLYLGSLTENAIAVLELGSLGAVKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU5</accession>
    <name>C7QGU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796520.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7972"/>
    <dbReference type="EnsemblBacteria" id="ACU76795">
        <property type="protein sequence ID" value="ACU76795"/>
        <property type="gene ID" value="Caci_7972"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7972"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_0_11"/>
    <dbReference type="OMA" id="GPSKLHM"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="16238" checksum="0FFE88CB9188E92A" modified="2009-10-13" version="1">MDSLDRAIIDVLRRDARASFADVGAEVGLSASAVKRRVDRLRADGAIRGFSVIVDQTALGWTTEAFVEVYCGDRTSPDVIRECVSRHPEVVAAYTITGDADALLHLVAENMRHLEEALERIRREPEIQRTRSALVLTRLLARDPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGW3</accession>
    <name>C7QGW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796538.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7990"/>
    <dbReference type="EnsemblBacteria" id="ACU76813">
        <property type="protein sequence ID" value="ACU76813"/>
        <property type="gene ID" value="Caci_7990"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7990"/>
    <dbReference type="eggNOG" id="COG1916">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009152_1_0_11"/>
    <dbReference type="OMA" id="EAGVWGT"/>
    <dbReference type="OrthoDB" id="1178576at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043737">
        <property type="entry name" value="DUF5682"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18934">
        <property type="entry name" value="DUF5682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="755" mass="81205" checksum="D777DA09833CDE5A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHS0</accession>
    <name>C7QHS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2176</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786388.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2176"/>
    <dbReference type="EnsemblBacteria" id="ACU71095">
        <property type="protein sequence ID" value="ACU71095"/>
        <property type="gene ID" value="Caci_2176"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2176"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_9_0_11"/>
    <dbReference type="OMA" id="APTIMHF"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="123"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="43566" checksum="B27FCAA4EA3949F7" modified="2009-10-13" version="1">MRIAYTEAQAQLRDTLRAYFTELVTPEVAEEMSTGEFGGPRSREAVRQMGRDGWLGVGWPEEYGGLGFTPVEQFVFFDEAQRAGAPVPFLTINAVGPAIMRFGTDKQKTEILPRILAGECMFAIGYSEPDSGTDLASLKTRAVLEPDGEHYLVNGQKIFTSLSDHADYVWLACRTDPEAPARTGKKHKGISILMVPTSDPGFTYTPIHTIGEASTYATYYTDLRVPAENVIGEPGEGWRVITTQLNHERVALCSSGSLERPFIEVVEWARQTKLADGSRVIDREWVRVHLARIQAKLAALRLFNWKVAASAELDVADASATKVWGTELYCEAYGLLLEVLGAAGALKKDSPGSLLAGRVERAYRGVLILTFGGGTNEIQRDLIALFGLNMPRIPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW5</accession>
    <name>C7QHW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786433.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71140">
        <property type="protein sequence ID" value="ACU71140"/>
        <property type="gene ID" value="Caci_2221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2221"/>
    <dbReference type="HOGENOM" id="CLU_2664354_0_0_11"/>
    <dbReference type="OrthoDB" id="771174at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="9044" checksum="C981A12F189AFAC9" modified="2009-10-13" version="1">MTSLERRPRAGPPTPNFSHSPTYWLEYSRIWVRDILPILAKYKYRQIKRDQIALWSNLADDMIDGINRWLDRHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIA5</accession>
    <name>C7QIA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794711.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6128"/>
    <dbReference type="EnsemblBacteria" id="ACU74982">
        <property type="protein sequence ID" value="ACU74982"/>
        <property type="gene ID" value="Caci_6128"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6128"/>
    <dbReference type="eggNOG" id="COG4280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1093150_0_0_11"/>
    <dbReference type="OMA" id="GMRWLRK"/>
    <dbReference type="OrthoDB" id="1519574at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25432" checksum="9060017DB4C2AAD8" modified="2009-10-13" version="1" precursor="true">MGTAFLLLSVFLACAVEAVEALTIVLAVGLTRGWRSALQGVAAGLLLLAAVVAGLGPALTVLPLKALRLVVGGLLLTFGLQWLRKAVLRASGYKDLRDEAAAYQRGVAAAKTAAASKRSVVEDWYAFTLSFKGVVLEGLEVAFIALTFGANQHDIPLAAVAAVAAVLTVCAAGVAIKAPLARVPENTMKFAVGVMLTGFGTFWGAEGAGAEWPGGDASLPLVLAYVLLVALGAVWVLKRRHAAWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIP3</accession>
    <name>C7QIP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8120"/>
    <dbReference type="EnsemblBacteria" id="ACU76943">
        <property type="protein sequence ID" value="ACU76943"/>
        <property type="gene ID" value="Caci_8120"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8120"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="2">
        <location>
            <begin position="139"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="978" mass="109629" checksum="3B48A776F2B360BD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIT3</accession>
    <name>C7QIT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796708.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8160"/>
    <dbReference type="EnsemblBacteria" id="ACU76983">
        <property type="protein sequence ID" value="ACU76983"/>
        <property type="gene ID" value="Caci_8160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8160"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_5_1_11"/>
    <dbReference type="OMA" id="TSITHGR"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="69"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="32046" checksum="E8A4142CD8F755EB" modified="2009-10-13" version="1">MARPAPAVDRTVAVLNLLAAHPDTAFSLSEMCRRLDINKATAHAMLTALAESGFLLRNPRDKSYTLGPALIALGSAAAARRLELVEFARAPMQTLAAATGLQCVVSSAMGEEIVFLAVAGEVVPFGPHVRVGQRIPLAPPIGTVFMAWSLPDDVDSWLNRSTTGKPLAEPELERFRNGVRAVRRRGYSVGLEPDVLGVRLGQSLDDHEAVPPLLAELSHTSYLMDDFGGSTHRIGHLAAPVFGPDERVAMVLTLYGFQKQLSGTDIDALATRLTATTREITFAVRGRHPDLRVSGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ01</accession>
    <name>C7QJ01_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ordered locus">Caci_0188</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784438.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0188"/>
    <dbReference type="EnsemblBacteria" id="ACU69143">
        <property type="protein sequence ID" value="ACU69143"/>
        <property type="gene ID" value="Caci_0188"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0188"/>
    <dbReference type="eggNOG" id="COG1197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_2_0_11"/>
    <dbReference type="OMA" id="WAPPCRE"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="648"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="827"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1182" mass="129475" checksum="37F86AF60617277B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ79</accession>
    <name>C7QJ79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784516.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0268"/>
    <dbReference type="EnsemblBacteria" id="ACU69221">
        <property type="protein sequence ID" value="ACU69221"/>
        <property type="gene ID" value="Caci_0268"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0268"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011855_0_0_11"/>
    <dbReference type="OMA" id="ADHVEFC"/>
    <dbReference type="OrthoDB" id="881553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1015" mass="112356" checksum="227677E2974DD96A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ83</accession>
    <name>C7QJ83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0272"/>
    <dbReference type="EnsemblBacteria" id="ACU69225">
        <property type="protein sequence ID" value="ACU69225"/>
        <property type="gene ID" value="Caci_0272"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0272"/>
    <dbReference type="eggNOG" id="COG0160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_0_11"/>
    <dbReference type="OMA" id="PLVPYNA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="49517" checksum="EA96DEDFF0CC705A" modified="2009-10-13" version="1">MYVLVMTEISSDDLKAAGAQVFADDRAHVFHSWSAQGAITPLPIAGAEGSYFWDYEGNRYLDFSSQLVNTNIGHQHPKVVAAIQEQAGKLCTIAPSFANDVRGEAARLIAELAPGDLNYVFFTNGGAEAVENAVRMARLHTGRTKVLSTYRSYHGSTSTAISLTGDPRRWANDAVGQSTGGAVHFFGPHLYRSHFHATTEAEECERALLHLEQTIQYEGPATVAAIILETIVGTAGVLMPPAGYLAGVRALCDKYGIVYIADEVMAGFARSGAWFAVDHWGVTPDLITFAKGSNSGYVPVGGVIISEKIRETFKDRVYPGGLTYSGHPLACASIVATINAMKEEGVIENAARLGEEVFGPALREIAAKHASVGEVRGVGAFWALDLVRSKETREMLVPYNASGADAAPMNELAAAMKARGVWPFVNFNRLHVVPPCTISEADARKGLAALDEALDVVDVYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJI6</accession>
    <name>C7QJI6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscL</name>
        <name evidence="11" type="ordered locus">Caci_2291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2291"/>
    <dbReference type="EnsemblBacteria" id="ACU71209">
        <property type="protein sequence ID" value="ACU71209"/>
        <property type="gene ID" value="Caci_2291"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2291"/>
    <dbReference type="eggNOG" id="COG1970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095787_1_0_11"/>
    <dbReference type="OMA" id="FKNFIMK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU71209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="14419" checksum="17A2300E4C80DA84" modified="2009-10-13" version="1" precursor="true">MFSGFKKFLMRGNVVDLAVAVVMGAAFGAIVNSLVKDIIMPLITAIFGKQDYTKLSFKIHNSTFAYGDLLTNVITFLSIAGAVYFLIVMPINHFNDRRKARLGIPEQAAAPTDVQLLAEIRDLLAAQRNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJN8</accession>
    <name>C7QJN8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Phosphatidylinositol phosphate synthase</fullName>
            <shortName evidence="10">PIP synthase</shortName>
            <ecNumber evidence="10">2.7.8.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">CDP-diacylglycerol--D-myo-inositol-3-phosphate 3-phosphatidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_2343</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + 1D-myo-inositol 3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85356"/>
            <dbReference type="ChEBI" id="CHEBI:144472"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>1D-myo-inositol 3-phosphate + a CDP-1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Contains a di-nuclear catalytic Mg(2+) center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786554.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2343"/>
    <dbReference type="EnsemblBacteria" id="ACU71261">
        <property type="protein sequence ID" value="ACU71261"/>
        <property type="gene ID" value="Caci_2343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2343"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080384_0_1_11"/>
    <dbReference type="OMA" id="DGNMARQ"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00220"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02241">
        <property type="entry name" value="PIP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044268">
        <property type="entry name" value="PIP_synthase_PgsA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="CDP-DAG binding" evidence="10">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>a CDP-1,2-diacyl-sn-glycerol</name>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21843" checksum="D756B6058BF65795" modified="2009-10-13" version="1">MLNRYARAFFTAVFTPIARFFLSRGISPDAVTLVGTLGVMAGALCFYPRGSFFVGTVVITAFVFSDLIDGTMARMLERKDKFGAFWDSTLDRLADAAVFGGLAWWFGRGGNQPVMFGVCLAIMGLGAVVSYARARAEGLGVDANVGYVERSERLVGSLVATGLSGLGVPYIQAVTLWAIAIGSLVTLAQRVLLVRKQLLKGEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY7</accession>
    <name>C7QJY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792954.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73225">
        <property type="protein sequence ID" value="ACU73225"/>
        <property type="gene ID" value="Caci_4361"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4361"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_0_11"/>
    <dbReference type="OMA" id="HEAKLFH"/>
    <dbReference type="OrthoDB" id="922937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="27"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="29306" checksum="7ED625629EF3C0D1" modified="2009-10-13" version="1">MGSDNLLGEFLKARRSRIAPSDREVALSGRRRVAGLRREELARLAGISEPYLTRLEQGVDRHPSPQVLSALARALELDADASAHFYALAAPDSEPSAEPEVSEDVHRLLDAWADTPAYVRNRRFDVLAANKPARALAAMYEPGRNLAREMFFSAQVRRLLPDWPQIAEQTVAALRAEADVRDPQTVQLIAELEGDEDFRRLWVRHDARPSRDELKRFAHPIVGELALRRQALTVGGAEQQVIIVYQAAPGSPSAEALARLVIGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB7</accession>
    <name>C7QKB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AzlC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794920.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6337"/>
    <dbReference type="EnsemblBacteria" id="ACU75191">
        <property type="protein sequence ID" value="ACU75191"/>
        <property type="gene ID" value="Caci_6337"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6337"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_4_0_11"/>
    <dbReference type="OMA" id="FIVLFME"/>
    <dbReference type="OrthoDB" id="1866750at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23597" checksum="149C0C04CD76D99C" modified="2009-10-13" version="1">MGYVPLGATYGLVLVNAGLAWYWATLSSLVIFAGAMQFLSVALLASGAPLAEVATTALLVNLRHIFYGLSFPLRRIEGPLRKLYGVFALTDETYSVVTAHSGEELSGRRIHLIQVFSHLWWVLGSTLGAAASTALPGQVHGIEFALTALFVVLAMEQLYKGGNARSAGYGAVAAVVAWLSAPGQFLSVALGILLAAAIGQWWLTSRRPSDRAADQAASTQGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR8</accession>
    <name>C7QKR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8344</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796892.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8344"/>
    <dbReference type="EnsemblBacteria" id="ACU77167">
        <property type="protein sequence ID" value="ACU77167"/>
        <property type="gene ID" value="Caci_8344"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8344"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035309_2_1_11"/>
    <dbReference type="OMA" id="NIFNYVG"/>
    <dbReference type="OrthoDB" id="1809199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="210"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="42441" checksum="7C45D34435656633" modified="2009-10-13" version="1" precursor="true">MPQVEPGGLTRNRIATFVFFGVQGFAFSLLTSKVSVIQKQLHVSDGTLAVLLALVPVLAGVGSVLAGAAMRWTTSAAVLRIAEPTVIGVLVIVPHTRNLYQAMPVLMVFGLAVGAADATMNMQACGLERRYGRSIILAFFGLWAAGAIVGSGWGALGSAAGWHLSVTYAVAAVVGVAATLYAGPMLLKNLRDETIVKDAEGRLPHIPWRPMLLLCVVMTLAYIGESSITAAGSDYLTKGLKSSDTFGGLVVGAYTVGQVLGRFRGDLAVQRFGNVKVVRAGAVVCAAGFAIVVGASGPYMALVGFLIAGFGLSPLVPVAFTAAYANDPTGSGVAVARINVFNYLGFLLGAPLVTGLWGAGVSHREGMAVPMVMIAVIVLLAYAFDPRRAPVRTGGLPTPAVGGAETVPTLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVW1</accession>
    <name>C7PVW1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786646.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2435"/>
    <dbReference type="EnsemblBacteria" id="ACU71353">
        <property type="protein sequence ID" value="ACU71353"/>
        <property type="gene ID" value="Caci_2435"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2435"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_2_0_11"/>
    <dbReference type="OMA" id="LPMCGTS"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043839">
        <property type="entry name" value="PafC_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19187">
        <property type="entry name" value="HTH_PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_PafC" evidence="2">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="144"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="35303" checksum="D729FD23D488D35C" modified="2009-10-13" version="1">MSGAAAQVRRLLNLVPYLLEHEGAKLTEVAGEFNVSEKQLRKDLETLWMCGLPGGLPDDLMEAHIGEGGTIHLENAEAIVRPLRFSVREAVALLVALRALAQLPGVADRDALLRAIAKLEEAAGERGAQASQRVTVAFEARATVLDRIRQALDSGHRLRLEYFVPSRDQVTERDVDPMRVILSDGHAYLEGWCRRSEAVRVFRLSRIVAIDVLDIAAEIPESAEPQDLDDGVLRPAADDPLVTLEVTRHARWVAENYPNEGVEELPEGGLRIALRAPDQGRILRLVLRLGADGRIVDPPALADQVRKTAAEALALYGAAEAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWI5</accession>
    <name>C7PWI5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6411"/>
    <dbReference type="EnsemblBacteria" id="ACU75265">
        <property type="protein sequence ID" value="ACU75265"/>
        <property type="gene ID" value="Caci_6411"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6411"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_20_12_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10687" checksum="09EF22EFE5A04047" modified="2009-10-13" version="1">MEPLDLRLVWALLAVAEEQSITRAAARLYVSQQTLSAQIQRLERVLGVELLSRSPRGVTLTAAGRELVAYGSGLSTELDELVVRLRAVAAAEEGTMLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX35</accession>
    <name>C7PX35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8469"/>
    <dbReference type="EnsemblBacteria" id="ACU77292">
        <property type="protein sequence ID" value="ACU77292"/>
        <property type="gene ID" value="Caci_8469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8469"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="YEESASH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="35106" checksum="3D6D631FE17F3880" modified="2009-10-13" version="1">MTSAEVPGRAAGTAPDGEPEEPDGAVERAARVPAGPSAPPIRRRRLGAALRRLRLGAGLTLQGAAERLEISDSTLSRLENGQGRLRRIDVAAALDVYGVEDEELRTTLLNLTGQIRDKGWWQYYRRAIPEPYADYISVEAAATSIDAHTVQLVHGLLQTEAYTRALAEAWRVRAEPLDVDALVAVRRTRQRMLGGAEPLRLRVVMHEGALRQSVGGPQVMRGQIERVIEESRRPNIIIQIITHSAGAYSGLDEPFAIVGFGNPLEHDVVCLDNLTRTHFLETVDEVRNYASVFDQLRAAALSPERSALWLADLLTKMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX65</accession>
    <name>C7PX65_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784711.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0464"/>
    <dbReference type="EnsemblBacteria" id="ACU69416">
        <property type="protein sequence ID" value="ACU69416"/>
        <property type="gene ID" value="Caci_0464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0464"/>
    <dbReference type="HOGENOM" id="CLU_762256_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="363" mass="40203" checksum="4867C98307B8FEB2" modified="2009-10-13" version="1">MASRLFDGALINDEPILKAQLKRTWRMLLMVVSASMAVVGLVFVVLRNHFGASSDIHNVVLEVGVNLALFGCTTLLVTVIASQQLEHQILGELNTRLNAHVKNVGDTMNEVQSEFRKTIETFLPLFGNGRDLGLDNIFLTRTDALIDIESHLRDELKSAAVESSRTGGPDDRDGPRARLWFVGTSLKGILEASALGFDGAGILSWAASLAAQDLLDLRVLLTHPTFARVRARQEHRAGTAIPEEISEALEFLHAHQVNAACIRMTQASPTVFAIATRERMLLNPYPYGAEAHRSFSIIVKRVHQEPNDHDSLHRDIFEQYEQRHFVRPWDDGLPVEQGAKEDPFVIPEATFNPLRPDGGDPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXG6</accession>
    <name>C7PXG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2501"/>
    <dbReference type="EnsemblBacteria" id="ACU71419">
        <property type="protein sequence ID" value="ACU71419"/>
        <property type="gene ID" value="Caci_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2501"/>
    <dbReference type="eggNOG" id="ENOG5033168">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080149_0_0_11"/>
    <dbReference type="OMA" id="HAPLYAL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009677">
        <property type="entry name" value="DUF1266"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06889">
        <property type="entry name" value="DUF1266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="27581" checksum="8170523781B9583D" modified="2009-10-13" version="1">MVDFGFKVLPDAPALTARQERGLALGAVYAVGDDLPINALTAGSDPQSAAKVLEQAWDVYDAQSARATYRFLLEEGGHRDVYACVRGYLNAGWDLSRADERARVEQATREIPAIAMQRGERPDVALNYFQSAWPSRAMMQGHYPRRIIESIAAWDAARVVHVSRFIVDAGYLPADEAWAAIDAAARMVLPEYPSWEEFQLGFLAGRVFWQCNGTFDAQEVSADYRRYTSSGKSLLSKADSPWQRLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXJ1</accession>
    <name>C7PXJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2526"/>
    <dbReference type="EnsemblBacteria" id="ACU71444">
        <property type="protein sequence ID" value="ACU71444"/>
        <property type="gene ID" value="Caci_2526"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2526"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_4_11"/>
    <dbReference type="OMA" id="FMTALRP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="40"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="142"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="21502" checksum="AD7DA6E2A34D9D43" modified="2009-10-13" version="1">MTSPRSEARQARLVAPERAAAPEAPRVLSSAAYPGWEAIYADNVERIYRLMYAKVGNRHDAEDLTSQVFLTAFGPLRATASVGEVRAYLLATARTVLATHWRSTLGHQVTVIDVDEAGLEDFSAPAQEERTGRTDERIGAILAGLPDRHRAILTLRFLRGYSIKAAAAELGVSVANAKVLQHRALRRAAGLDKEGEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXK6</accession>
    <name>C7PXK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786752.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2541"/>
    <dbReference type="EnsemblBacteria" id="ACU71459">
        <property type="protein sequence ID" value="ACU71459"/>
        <property type="gene ID" value="Caci_2541"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2541"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="FKVATVQ"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="14"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="30366" checksum="9E714642BFAD1791" modified="2009-10-13" version="1">MQTRRIGDTAVSAIGLGGMPMSIEGRPDAQRSIATIHAALEAGITLIDTADAYHLHADEVGHNESLIAGALASYGGDTSEVLVATKGGHLRPGDGSWTQDGSPEYLKRACEASLKRLGVDSIGLYQFHRPDPRVPYADSIGAIRDLLDEGKIQMAGISNADRDQIRQATEILGGRLVSVQNEFSPRFRSSEPELELCAELGLAFLPWSPLGGISRAAGLGSHFAVFAEIGEAHGVSPQQVCLAWLLAKAPVVIPIPGSSRPETIRDSAAAVDLVLSAEEFARLDARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP3</accession>
    <name>C7PXP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786789.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2578"/>
    <dbReference type="EnsemblBacteria" id="ACU71496">
        <property type="protein sequence ID" value="ACU71496"/>
        <property type="gene ID" value="Caci_2578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2578"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_4_11"/>
    <dbReference type="OMA" id="PINFAYT"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="52155" checksum="3850571D3CCF2736" modified="2009-10-13" version="1">MEWSFRTAEELAAALRAGEVTSGELTEEAIARIERDDKVINAICVPDFDRARAAARAADQARARGEDRPLLGIPVTVKESYNMAGLPTTWGMPHHGNYMPAEDSVQVSRLKDAGAVILGKTNVPLGLQDIQSFNEIYGTTNNPWDHTRTSGGSSGGSAAALASGFGALSIGSDLAGSLRTPAHFCGVYSHKPSLGLVPSRGMVPPSAPALPVDLDLAVVGPMARTARDLTLLLDVMAGPDPLTYGTAYQLALPPARHERLSDFRVLVLEEHPFLPTGSAVRAGVNRVADALADGGARVERHSPLLPDLTEGATLYAQLLFSGSVARFPVDAYERLRTRAAALSPEDQSLDAARLRAMVFSHRDWMEANDRRELHRHGWRQFFAEFDAVVCPITPTPAFPHDHNPNPLERWIDIDGVDFPYFDQLVWAGLPTMPGLPATVIPTGLSPEGLPVGVQLIGPMFEDRTPLSLAELLEQKIGGFRPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYY6</accession>
    <name>C7PYY6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0606"/>
    <dbReference type="EnsemblBacteria" id="ACU69542">
        <property type="protein sequence ID" value="ACU69542"/>
        <property type="gene ID" value="Caci_0606"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0606"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062604_0_0_11"/>
    <dbReference type="OMA" id="MEAHYPE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33394" checksum="201C6510D618B844" modified="2009-10-13" version="1">MSDQRTTTAGRKHIRVAVAQTTLVEDPRDAGRLRAAGEQVRKLMREAARDGARLVLFPEGAMCAPNKRIVSSLPDEVGPADWSRFAWDVLREELSAVAELAGELRLWTVLGSVHRLTPPNRPHNSLYVISDRGEVAGRYDERLLSKTKVTYMYAPGTATVTFDVDGVRFGCLLGMEVHYPELFAAYEQQGVDCVLFATTGSTPAEQSPTFATEAQGLAAVNGMWVAFAGSAAVGSATPSGLLGPDGTWSARCEPSTAAAVVVGEIDDGAAEVEIAVRYARPWRREARSGLYEEHRVVADPRSEARSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ10</accession>
    <name>C7PZ10_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease VapC</fullName>
            <shortName evidence="6">RNase VapC</shortName>
            <ecNumber evidence="6">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Toxin VapC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">vapC</name>
        <name evidence="8" type="ordered locus">Caci_0630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Toxic component of a toxin-antitoxin (TA) system. An RNase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PINc/VapC protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784861.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0630"/>
    <dbReference type="EnsemblBacteria" id="ACU69566">
        <property type="protein sequence ID" value="ACU69566"/>
        <property type="gene ID" value="Caci_0630"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0630"/>
    <dbReference type="eggNOG" id="COG1487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118482_8_2_11"/>
    <dbReference type="OMA" id="VINPWEA"/>
    <dbReference type="OrthoDB" id="1968541at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00265">
        <property type="entry name" value="VapC_Nob1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022907">
        <property type="entry name" value="VapC_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0800">Toxin</keyword>
    <keyword evidence="1 6" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="PINc" evidence="7">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="15104" checksum="C58FF69699910ECE" modified="2009-10-13" version="1">MIIIDTNVFSELMRPAPDAAVAAWVEEFGRDLFLTAVSVAELRHGILRMSGGRRRSDLMTDTDALLAEFDQRVLPFDVAAAEYYAMVVASRFAGGRPISFPDAQIAAICQAHGALLATRNVKDFEYLGLTVIDPWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ81</accession>
    <name>C7PZ81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase BadF/BadG/BcrA/BcrD type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786831.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2621"/>
    <dbReference type="EnsemblBacteria" id="ACU71538">
        <property type="protein sequence ID" value="ACU71538"/>
        <property type="gene ID" value="Caci_2621"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2621"/>
    <dbReference type="eggNOG" id="COG2971">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016274_1_1_11"/>
    <dbReference type="OMA" id="TESWRIR"/>
    <dbReference type="OrthoDB" id="1589192at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BcrAD_BadFG" evidence="1">
        <location>
            <begin position="11"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="32208" checksum="C865340CAA88E8EF" modified="2009-10-13" version="1" precursor="true">MSVTSPNPAVVGIDIGGTKTHLAVGAVGAVGAVGTSSTDAAVREHVVATSAWRTADVVADAKALAELIGRHLGEEAKSLPTALGAHGCDSTEQCLALEAELSRHLAGPVRVVNDAELMTWAMGVADGIGVVSGTGSIAVARDRHGRLVTSGGWGWVLGDEGGAAGIVREAVRAVLAELDAGGGQDPLVAALFAGFGVDGGPELAMALTRRSSADWWGSHAGLVFAAADQGSRIAGRVVDEAGTQLAGLVTRLLARGVRTEHVVIGGGVVTAQSRLREKFLSILARDRPELSVSVLDRPPVTGALALAMSLVPHLEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZB8</accession>
    <name>C7PZB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA binding S1 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786868.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2659"/>
    <dbReference type="EnsemblBacteria" id="ACU71575">
        <property type="protein sequence ID" value="ACU71575"/>
        <property type="gene ID" value="Caci_2659"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2659"/>
    <dbReference type="eggNOG" id="COG0539">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194361_0_0_11"/>
    <dbReference type="OrthoDB" id="1235756at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="82" mass="8907" checksum="5AC79A716C118316" modified="2009-10-13" version="1">MPHQDGAHSAWDLFVAGHEVGDVLIAPVTKAVPVGVFVRLSKTIEGLVHQDSLSGAPDVGDLLRVRIDEIDRTRRRVRLSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZH5</accession>
    <name>C7PZH5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786925.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2717"/>
    <dbReference type="EnsemblBacteria" id="ACU71632">
        <property type="protein sequence ID" value="ACU71632"/>
        <property type="gene ID" value="Caci_2717"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2717"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="INYVTMA"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="438"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="58070" checksum="76CDF652CE2B75CA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP5</accession>
    <name>C7PZP5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4699"/>
    <dbReference type="CAZy" id="PL9">
        <property type="family name" value="Polysaccharide Lyase Family 9"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73560">
        <property type="protein sequence ID" value="ACU73560"/>
        <property type="gene ID" value="Caci_4699"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4699"/>
    <dbReference type="eggNOG" id="COG3420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026896_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981354" description="Beta_helix domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="143"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="47990" checksum="932897296E0C334A" modified="2009-10-13" version="1" precursor="true">MKPHALGLAALSALVFSVVAVPVSAQADTTSTVYVAPSGSDSAGGTLAAPFATIQHAIAALPSGGGTVVVRGGRYAQRVSLHNAKNITLTAASGEHPVLDGSSLTVPTGRSAMVDIAGSTAVTVRGLEITGYRSADIAAMPIGIYVHGGDTGVTIAGNHVHAMGNDNGTLGSMDMNAHGIAAYGDSPTRPISTLTIDGNEVDHLKLGASESVVVNGNVDGWRITGNHIHDDNNIGIDAIGFEPTLPPSYRYTDLNRARDGVISGNDVENIVSEGNPAYWSPEGWCNCADGVYVDGGTHIAIAGNSVRGDDIGIEVAAENARGAADHVTVEGNAVSDSRYVGITTGGYCDGGEDCGGVQTGRSFANTFTGNTLRNNNTDHDGSPEFLIQYHESGNQITGNTICAAGPGTLLIGTVARSTSGQGDVVDANRYSAAAAAGAATAQWGWHATTYTGFSAYRAATGLDAHSSFSGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0B3</accession>
    <name>C7Q0B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797170.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8630"/>
    <dbReference type="EnsemblBacteria" id="ACU77446">
        <property type="protein sequence ID" value="ACU77446"/>
        <property type="gene ID" value="Caci_8630"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8630"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="SCERIEQ"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="135"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="36402" checksum="D2D8584F53A6D2A6" modified="2009-10-13" version="1">MNPATCLRVLRNSAQCRLTAALTTVFLVGGTVLMGVAYLLVKARLPNKTAEIIVTPNSGDSRALTDSAKLTAAREAATHAVAEANANAVHQILVYGLWSLAALTVLAGALGWWMAGRALRPVHTMIAGQRRFAANASHELRTPLAVQRAAIQIGLEDPTPAELAEVREQLLTANIRTQKLIDGLLLLASSESGVHEREPVRLDLLVAAEVARYAEDADEAGVRLVTRTKPHAESPSPVLVLGDEVLLGHLVGNLMRNAIAYNQPGGTVEVDVGTDRTLRIENSGRPVPPGDVARLFEPFERGSRGEGSGLGLSIVRAITTAHGGRIRVRPGRQGGLAVSISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0C6</accession>
    <name>C7Q0C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8643"/>
    <dbReference type="EnsemblBacteria" id="ACU77459">
        <property type="protein sequence ID" value="ACU77459"/>
        <property type="gene ID" value="Caci_8643"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8643"/>
    <dbReference type="eggNOG" id="ENOG50339I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435960_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="627" mass="67394" checksum="9AA2827981BD6297" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q196</accession>
    <name>C7Q196_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787064.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2862"/>
    <dbReference type="EnsemblBacteria" id="ACU71771">
        <property type="protein sequence ID" value="ACU71771"/>
        <property type="gene ID" value="Caci_2862"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2862"/>
    <dbReference type="HOGENOM" id="CLU_2394392_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="9856" checksum="28D8D9D7E2D8CA4B" modified="2009-10-13" version="1">MKAALVELEAKGHALITQLEEREHALAAEFRAWFNELTGHLPAVEAEVKSDAEQVAHDAKTAAAPVVAEAEQDVQSVAREVAADVSTAAEPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C2</accession>
    <name>C7Q1C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4790"/>
    <dbReference type="EnsemblBacteria" id="ACU73651">
        <property type="protein sequence ID" value="ACU73651"/>
        <property type="gene ID" value="Caci_4790"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4790"/>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_914287_0_0_11"/>
    <dbReference type="OrthoDB" id="1203604at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33868" checksum="E069DFCE58C65824" modified="2009-10-13" version="1">MLIFSSSDKGGTGRSVTSCNMAYRLSLLGRDVAYLDFDFGSPTAGAIFEIPKLERGTQDGGLHSFILGQTTVPTRVDVRKVTERPALQERPSGSGKLTLFPGDVGGAEFHLSDDHIKAAISLFQTVEREFDVCIVDLSAGRSSALDMSLNAISPRVRKKTREGNDRVRWLLFHRWTTQHVIAAGGLLFEQNGILPCAVEAGFAQADFMRLVRTVRTAVPDASAFGEKTTAEQTRWVVRSDDHLKALAQGRGLGQDLLAGTTPLEPMLLWREQVIMDLDVNRRLAKPATTQAFDKLAIRVVDDHAWEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C5</accession>
    <name>C7Q1C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4793"/>
    <dbReference type="EnsemblBacteria" id="ACU73654">
        <property type="protein sequence ID" value="ACU73654"/>
        <property type="gene ID" value="Caci_4793"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4793"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_5_0_11"/>
    <dbReference type="OMA" id="VCWAAEA"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019951">
        <property type="entry name" value="F420_OxRdatse_Rv3520c_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03559">
        <property type="entry name" value="F420_Rv3520c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="37463" checksum="FA6B61CBD77F5955" modified="2009-10-13" version="1">MRLGVNMGYWGAGNDAESLQVAKEADRLGYAVCWAAEAYGSDAATVLTWIAAHTEHMDVGSAVFQIPARTPAMTAMTAATLDTLSNGRFRLGLGVSGPQVSEGWHGVPFASPLGRTREYVAIVRKALTRERLTYDGKHYTLPLPGGPGKPVKLTVHPVREHIPVYLAAIGPKNLELTGEIGDGWLPVFFSPEHASEHLEHIKTGRAKAGKNSLDGFDIAPTVPTVVGDDVHLCADLVRWYAALYIGGMGSKDQNFYNQLACRMGYEKQADEVQQKYLAKDYAGAAAAVPFEFIDRTSLIGPKERIAERMAAYKDSGVTTLSVGAAFGDLETRIGIVRAAVEAAEMAGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D9</accession>
    <name>C7Q1D9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793397.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4807"/>
    <dbReference type="EnsemblBacteria" id="ACU73668">
        <property type="protein sequence ID" value="ACU73668"/>
        <property type="gene ID" value="Caci_4807"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4807"/>
    <dbReference type="eggNOG" id="ENOG502ZU7R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2536416_0_0_11"/>
    <dbReference type="OrthoDB" id="1475207at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="9101" checksum="C3DC9AD65C5C53FC" modified="2009-10-13" version="1">MVSWSAADHNLDDVIAEYGPASITFGDPHARSAKTLAYATDDRQAPFVAFHLDATESVAALLAVRLNDDFFNGWRFTPRGMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1I9</accession>
    <name>C7Q1I9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate protein TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4857</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793447.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4857"/>
    <dbReference type="EnsemblBacteria" id="ACU73718">
        <property type="protein sequence ID" value="ACU73718"/>
        <property type="gene ID" value="Caci_4857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4857"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_0_11"/>
    <dbReference type="OMA" id="AANWYAR"/>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="199"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="388"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="603" mass="65290" checksum="D2E116AB1923F251" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1M4</accession>
    <name>C7Q1M4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793482.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4893"/>
    <dbReference type="EnsemblBacteria" id="ACU73753">
        <property type="protein sequence ID" value="ACU73753"/>
        <property type="gene ID" value="Caci_4893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4893"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_519641_0_0_11"/>
    <dbReference type="OMA" id="MELGNAY"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046278">
        <property type="term" value="P:3,4-dihydroxybenzoate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012794">
        <property type="entry name" value="PcaR_PcaU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02431">
        <property type="entry name" value="pcaR_pcaU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="73"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="354"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="549" mass="58845" checksum="6CB8FC51D7B844CA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2H3</accession>
    <name>C7Q2H3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785110.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0882"/>
    <dbReference type="EnsemblBacteria" id="ACU69815">
        <property type="protein sequence ID" value="ACU69815"/>
        <property type="gene ID" value="Caci_0882"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0882"/>
    <dbReference type="eggNOG" id="ENOG5032WDS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1183300_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="26739" checksum="919AC5F12D313504" modified="2009-10-13" version="1">MICFFDPAHGQASVNVMWQPQWGVARPVEVCQYCAQRVQTTQPPYYQPVQQQGYPQQGYPQAGYPQQQGYPAQQPGYAQQGQYQQPPRQGHSTGAMVGAGAAGLVGGMLLGEMLEGDDTKRDEQQAYERGFEERGYDDQRSEYQQQEFQQQEFQRDQYQQPEYQQPDYQQPQYQSEYQQPEYQQPEYQQPEYQQPEYQQTDYGSGGDFGTDYNAGGFDGGGDYTNDSGDNGGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P8</accession>
    <name>C7Q2P8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787083.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2881"/>
    <dbReference type="EnsemblBacteria" id="ACU71790">
        <property type="protein sequence ID" value="ACU71790"/>
        <property type="gene ID" value="Caci_2881"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2881"/>
    <dbReference type="HOGENOM" id="CLU_1934249_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13935" checksum="5A136F391FBCFB02" modified="2009-10-13" version="1">MTERSAARHAQTTAFAKALRSLADWLEQDSTLPVPEYLPIVISLDSAEAVADIAIGHNLDGPFTAADGPPFLYRAFGAGVTWQAVHYANRTGMSEDEAHARAWAAQHGFVLLPRTDTVHTHHATGGAPCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Y9</accession>
    <name>C7Q2Y9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phage polynucleotide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787174.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2972"/>
    <dbReference type="EnsemblBacteria" id="ACU71881">
        <property type="protein sequence ID" value="ACU71881"/>
        <property type="gene ID" value="Caci_2972"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2972"/>
    <dbReference type="eggNOG" id="COG4088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911914_0_0_11"/>
    <dbReference type="OrthoDB" id="813344at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="34034" checksum="08C027578C06079A" modified="2009-10-13" version="1">MPTIHLTCGLPASGKTSLARQLVAESAGRMRRVNLDDLRLMLDANDGRIRLGRDHEETVLAVQDAAVLAAIDGGFDVVVDNTHLVSRIPNRLKRVVAGRADFAVYDFTGVDVEECIGRDKVRERPVGEDVIRSMAERLKSTRDGWWKHPERLNDTPVPEPYVPDLSLPPAVLCDIDGTLAIHAGRGAYDLDLCETDLLNEEVARVLALCDRADGYIVLLSGRQSEFRKHTERWLAAHQVPYDELWMRAEGDRRSDDIVKAELFDAHVRGLYNVRFVLDDRARVVALWRRLGLKCWQVAYGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q305</accession>
    <name>C7Q305_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787190.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2988"/>
    <dbReference type="EnsemblBacteria" id="ACU71897">
        <property type="protein sequence ID" value="ACU71897"/>
        <property type="gene ID" value="Caci_2988"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2988"/>
    <dbReference type="HOGENOM" id="CLU_2567563_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="9122" checksum="5A65E09F633FEC26" modified="2009-10-13" version="1">MRTSEYYAQGIHGFFVGYALDALDQNRRADEAPAEEPEPEAPEYDMDAAFVKCTGCFCHTTAYPPCMHCEDGHDDEREVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q328</accession>
    <name>C7Q328_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4904"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73764">
        <property type="protein sequence ID" value="ACU73764"/>
        <property type="gene ID" value="Caci_4904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4904"/>
    <dbReference type="eggNOG" id="COG3507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016116_0_0_11"/>
    <dbReference type="OMA" id="DQWDSNS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982462" evidence="3">
        <location>
            <begin position="34"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="349"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="51541" checksum="B352E46A24F12FF4" modified="2009-10-13" version="1" precursor="true">MPIRARRSTVSALIAAVTTALSLVGLSQTSAQAATSQFSPGQTWNDTSGTALQMHGLGIVKVGSTWYGFGEDKTGENSGNAAFQDIPCYSSTDLSHWTLQGKALTRQTSGDLGPNRVVERPKVLFNASTNTFVMYMHIDSASYGEAKVGVATSSTPCGPYSYRGSFQPLGRQSRDIGLFQDTDGTGYLLSEDRASGLRVDKLSADYLSVVSAGGSGGSVALFADYEAPAMVKTNGTYFVLGSHLTGWNLNDNVYATATSLSGSWSSFKDFAPAGTNTYQTQTANIIPVSGSAGTSYIYAGDRWNPNNLGGSQLVWLPLTLSGTTANVGWQNSWSLDVAAGTWSGSSNPASGSTHHLTNANSSMVMDVSGGSTASGGAVIQWAGHGGTNQQWTLHQVAGNVYTLTNQNSGLCLEVPNRSTATGTALDQWTCGGGSNQQWALDPVGSYTSSSDASYELTNLNSGLVADVSGGSTAQGAQVIQWTTNGQANQTWTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q339</accession>
    <name>C7Q339_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein</fullName>
            <shortName evidence="2">P2TMN nickel insertion protein</shortName>
            <ecNumber evidence="2">4.99.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nickel-pincer cofactor biosynthesis protein LarC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">larC</name>
        <name evidence="3" type="ordered locus">Caci_4915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide = Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide</text>
            <dbReference type="Rhea" id="RHEA:54784"/>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <dbReference type="ChEBI" id="CHEBI:137372"/>
            <dbReference type="ChEBI" id="CHEBI:137373"/>
            <dbReference type="EC" id="4.99.1.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.12" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4915"/>
    <dbReference type="EnsemblBacteria" id="ACU73775">
        <property type="protein sequence ID" value="ACU73775"/>
        <property type="gene ID" value="Caci_4915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4915"/>
    <dbReference type="eggNOG" id="COG1641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028523_2_1_11"/>
    <dbReference type="OMA" id="TCLGLDW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="39828" checksum="37080E3F92A359F8" modified="2009-10-13" version="1">MICWINPFTGLAGDMLLAALLDAGAPLEQVRTAVAATGLTGWELTAERVSDHGLTGTRVRVRVTDHAAERRAAELIALASAATPPPVAARAVAALRAIAEVEARIHGADPAAVHLHELGGHDTVVDIVGVAAAMHALGVDDVVCAPLPLGTGRVRSAHGLIPAPAPATLALLAGAVVVGTDLPGETVTPTGAALLRALNARFDPVPAMTVRATGYGFGTRRLPDRPNVVAVTFGERQRGGGGGDGETVTVLETNLDDVTGEVLGHVIARSLEAGALDAWATPAVMKKGRPGHVLHLLVEQQDCDALQELLFAETGTLGVRRATVDRTVLPRHFETVHVDGVPVSVKHGPYGAKPEHDDLVAAAGRLGLPLRAVAERAMRLSSGSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q399</accession>
    <name>C7Q399_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4975"/>
    <dbReference type="EnsemblBacteria" id="ACU73835">
        <property type="protein sequence ID" value="ACU73835"/>
        <property type="gene ID" value="Caci_4975"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4975"/>
    <dbReference type="eggNOG" id="ENOG5033C5F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056543_1_0_11"/>
    <dbReference type="OMA" id="PLFEQNW"/>
    <dbReference type="OrthoDB" id="1808992at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043857">
        <property type="entry name" value="DUF5819"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19136">
        <property type="entry name" value="DUF5819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="25554" checksum="CAE54E1A84FD3938" modified="2009-10-13" version="1">MNDMSSTAIEPLPHISETYAVGGDDAVPRVRLSRPVEVAVVAAVALCLTAAVVHVAMVFLYVAPSNTVSQTYRKQIDAWVYPYFEQDWRLFAPDPQSARQEISARTSTVAPDGATRLSGWIDLTAVDDAAVRHDVFPSHTAQNMLRRAWAAYADADAQGAGGQPASQRAAMLQAYLRNIAVQRASAAHHVNFSAIQLRVVTTPIAPPSLGAVPNRPAASPSSVRYLPWWQVTTHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3P3</accession>
    <name>C7Q3P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75808">
        <property type="protein sequence ID" value="ACU75808"/>
        <property type="gene ID" value="Caci_6978"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6978"/>
    <dbReference type="HOGENOM" id="CLU_1479529_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19959" checksum="170DC2D219261E04" modified="2009-10-13" version="1">MSMSTGPGEQWIVKTAAGQTQIGIDYLWPDGTYDKKHYGPFDVCTENPVNPLDPDAGHRQYCVQTRPAQQFYGALTVDETDSTVSYSVANHDYGRYLIKAVPVPIPLATQPTSGSYSVQNGQYIVPGHNEPAAMSLGQLANALLDPRFNDYLIHYENYVLTHATADSFSVSGSKPLKTEGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S8</accession>
    <name>C7Q3S8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_8873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8873"/>
    <dbReference type="EnsemblBacteria" id="ACU77686">
        <property type="protein sequence ID" value="ACU77686"/>
        <property type="gene ID" value="Caci_8873"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8873"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="WCAVIAS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU77686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="270" mass="28134" checksum="018176095F372DDA" modified="2009-10-13" version="1">MTTQMPTHMTTQSHTLTDTFTLLRRNLRHTVRYPSMTLGSVFGPVVMLLLFVGVLGKTLGEGLATGAQGSGYIGYIAPGIIITAVASGSMATAVAVCVDMTEGIVDRFRTMPISRVAILAAHVVNSVITTVVSTGAVILAAVLLGFRPHASVLEWMAGAALLLTLSFALTWMAVAMGLVSPTAEAASNAPMLIVFLPFVGSAFAPAASMPAGVRQFAEYQPFTPAIETVRGLLTGAPIGDNAVISLVWCAVIASGGYAWAVASFRKPRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3T8</accession>
    <name>C7Q3T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8883</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797420.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8883"/>
    <dbReference type="EnsemblBacteria" id="ACU77696">
        <property type="protein sequence ID" value="ACU77696"/>
        <property type="gene ID" value="Caci_8883"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8883"/>
    <dbReference type="eggNOG" id="COG1064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_11"/>
    <dbReference type="OMA" id="YRFSIDM"/>
    <dbReference type="OrthoDB" id="969875at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="8"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="36393" checksum="395370EF4511017B" modified="2009-10-13" version="1">MPTVNAFAAVSATAPLQPITIERREVGPRDVRIDIKYTGICHSDIHEVRGDWGECPYPLAPGHEITGVVSAVGAEVTRFSVGDRVGVGCLVNSCGQCKECERGQEQFCSVKAVWTYGDTDVDGTVTQGGYSTQIVVTDRFVVHIPDALPLETAAPLLCAGITTYAPLRRWGAGPGKKVAVVGLGGLGHVAVKIARALGAEVTVLSQTLSKKDAGLALGASDYRATSDPATFADLAGTFDLIVSTVSAPLPMDSYLLMLGVGGAMINVGAAPEESGLHLRILNRQRVLAGSLIGGIAETQEMLDFCGEHGIGAEVEIIAAEQINEAYERVLASDVRYRFVIDISTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Z1</accession>
    <name>C7Q3Z1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797473.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8936"/>
    <dbReference type="EnsemblBacteria" id="ACU77749">
        <property type="protein sequence ID" value="ACU77749"/>
        <property type="gene ID" value="Caci_8936"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8936"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127701_0_0_11"/>
    <dbReference type="OMA" id="DPKRSHI"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16685" checksum="535B3BB68EB092AB" modified="2009-10-13" version="1">MGERPEDADDIGVIAKRIEHLFTTVYPGSLGRPYTLREAVEKINADAGENLISVAYLSQLRNGDKRHPAFDKLAGVAKLFGVSTDYFLDDETAARTDQQLALVAAMREQGVDRLATRSLGLSANSLEAILGMIENARKIEGLPDDEGDVPAQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q457</accession>
    <name>C7Q457_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785211.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0989"/>
    <dbReference type="EnsemblBacteria" id="ACU69917">
        <property type="protein sequence ID" value="ACU69917"/>
        <property type="gene ID" value="Caci_0989"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0989"/>
    <dbReference type="eggNOG" id="COG3393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093867_0_0_11"/>
    <dbReference type="OMA" id="SWRVYER"/>
    <dbReference type="OrthoDB" id="1563557at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FR47" evidence="1">
        <location>
            <begin position="200"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="27627" checksum="2E1A771CF90CEC9B" modified="2009-10-13" version="1">MESLEAKVNGYLHGNARARATNEACGPFHIGLDDNNANPFLNYAVPEAGATVTAADIEALIAAFAKRERTPRLEFAPGGAPGVEEALLAAGFEVQQRLPFMVVTAEELVGPAQLDGIEVLVLDTSATDEELSGAALAQHEAFEGPDKPQDDTERANALAGMRAMVDAGRFASLARCAAGSASAGVPMAAGSGGPAIAGTTEIGGIGTRPAFRRRGAGAAVTAALSRHLLEVAGLDCVWLSPAGPDQERLYASIGYRSLGEMLFIWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J8</accession>
    <name>C7Q4J8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3058"/>
    <dbReference type="EnsemblBacteria" id="ACU71967">
        <property type="protein sequence ID" value="ACU71967"/>
        <property type="gene ID" value="Caci_3058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3058"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_17_5_11"/>
    <dbReference type="OMA" id="DLRHTHK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="439" mass="49277" checksum="4A18DBF99A54F9A3" modified="2009-10-13" version="1">MAYAEKRPGGWTVRVKVGVDPDTGNDVYRRISKDPTTGQLFATKTRARNFGNDQEAEIRAGTWIDPKKAETTLADWWADWIKAQEVDTGTIAFYDSLWRNHLGPRWGATTLGEIRRGKFTEWLKGVGAGTIETGPADKRVTRKYAPRTINGIGKLASLMLEDAAEEQMIGRNPLAQEGRKRTRGRRATRRRTTIRVKLDVSPAEVMMIAVNMNELCGPVGFVRTVMAAWTGARPGEQAALKRDQCHAMAARPLIRIDDDEGTTQEYGGKVTLAPPKGGLGRDVLLPPSLATLLTDWLKTHPADSTVVKGPHGDHWRRRQWNERWRPACDGKPELRRVGRQFEPTGGWVISPVVPRLEFKGLRRAHNVWMTDDGIAEVARAHRLGHAMSDEMQAAYSVVSREMERKLLDALERRWQEALSPEAWEIISQISPTLAKKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4T7</accession>
    <name>C7Q4T7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5025"/>
    <dbReference type="EnsemblBacteria" id="ACU73885">
        <property type="protein sequence ID" value="ACU73885"/>
        <property type="gene ID" value="Caci_5025"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5025"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="NNWHLIF"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="59"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="28385" checksum="F211DB5048781439" modified="2009-10-13" version="1">MAAGLLTLAFVSPIYLTIVNAFKSQSQIVRDPSAPPAPPTLHNITDALGRSDKIIQIGLTNSAVTVLASVLLVVPLGSAFSFWLTRRSARVRRSVLAVFAAGLMIPPAVVLLPTIRILTILHLDHTYPGLVLSNVGGGYLSFAVFVYSGFLRAVPGEVVEAAALDGAGMVRIWWTIVMPLLRPATATVAIFLSLWIWNDFMNPQFILGPLRGQTITTGLYQSLGQYSTNYAQLFGVMFLAAVIPVAGYLALQKQFIAGLTTGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4X9</accession>
    <name>C7Q4X9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793656.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5067"/>
    <dbReference type="EnsemblBacteria" id="ACU73927">
        <property type="protein sequence ID" value="ACU73927"/>
        <property type="gene ID" value="Caci_5067"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5067"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_0_0_11"/>
    <dbReference type="OMA" id="YLLTEWI"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="2-oxoacid_dh" evidence="5">
        <location>
            <begin position="148"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="363" mass="38103" checksum="4A975A91B9265D7B" modified="2009-10-13" version="1">MTEVRVPKLSNNDSEYLLTEWIAEHGKPIAVGDPVATVETSKAAEELAAEEAGYLSQLVPVGSTVTPGQLIATVSQTAPSAEAPAPVRLPESDGAGVSGAVGTSDVVITGPARTLMEELGIKEERVVALGIKVVRRTDIAELAAAVPTQPLSRVQQAVGRAVSESHATIPAAYTAMKMDIGRSLAEAAALSKEVKRPVGLTEIFVRAVAGLHDRFPLIFAALDGDRARLADVAHIGVTMDLGEGLYVPVVRDAAQLGVKELASQLMRFRLAAVEGNFRAEDLDGANFTVTLHTDPDVTLAIPFVFPGQVCALAVTAPQREPVLDEAGALTTRTVAAIGLAYDHRLINGRDAAAFLTALKEDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5B3</accession>
    <name>C7Q5B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795610.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7052"/>
    <dbReference type="EnsemblBacteria" id="ACU75882">
        <property type="protein sequence ID" value="ACU75882"/>
        <property type="gene ID" value="Caci_7052"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7052"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_8_1_11"/>
    <dbReference type="OMA" id="IAFMDIM"/>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="11"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="104"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="12698" checksum="CA43B46F56342BEC" modified="2009-10-13" version="1">MADGQPQPDCLFCKIVAGEIPATVVRETDLTLAFKDINPQAPVHDLIVPRAHYANAAELAFGAPELAAAVLLEAREVAKTEGIADGGYRVVFNTDAHAGQTVFHVHAHVLGGDFLAHFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5H6</accession>
    <name>C7Q5H6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ordered locus">Caci_8974</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8974"/>
    <dbReference type="EnsemblBacteria" id="ACU77787">
        <property type="protein sequence ID" value="ACU77787"/>
        <property type="gene ID" value="Caci_8974"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8974"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_6_3_11"/>
    <dbReference type="OMA" id="NFACACD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="8"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="322"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="239"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU77787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="471" mass="51842" checksum="52C2960FCAD8665B" modified="2009-10-13" version="1">MTSPGVPIRVRFAPSPTGMFHVGGARSALYNWATARQQGGTFVLRIEDTDAARNKPEWTEGIISALAAIGISTADPAFEGPYFQSQNADRHRKAAEQLLAAGRAYYCDCTREQVAERTGSEQLGYDGFCRDRGLAYEPGRAMRFRTPDEGQTVVVDLIRGTPSFPNSAIEDFVIARGDGSPVFLLANVVDDLDEGITEVIRGEEHLSNTPKQQLLWEALGATPPIWAHLPVIVNEKRQKLSKRRDKVALEDYLSEGYLPAAMVNYLMLLGWGPKDGVELRPYSELEELFRVEDVNNSSAFFDVRKLASFNGEYIRALTATDFVEACQPWLRSPRAPWAPEDFDASVFEQVAPLVQTRITVLGEVVDYVDFLFLPAPVHDEQSWSKAMKPGAADMLRGSRDALAGCDWRAADIQTALEGVAASLELKMGKAQAPVRVAVTGRTVGFPLFESLESLGRERTLSRLDAALAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5M6</accession>
    <name>C7Q5M6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ordered locus">Caci_9024</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797561.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9024"/>
    <dbReference type="EnsemblBacteria" id="ACU77837">
        <property type="protein sequence ID" value="ACU77837"/>
        <property type="gene ID" value="Caci_9024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9024"/>
    <dbReference type="eggNOG" id="COG0136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_0_0_11"/>
    <dbReference type="OMA" id="MFDVPDE"/>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="42"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU77837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="36767" checksum="9B1488EF6E2D8FEC" modified="2009-10-13" version="1" precursor="true">MTGKKPTLAVVGATGAVGTVMLDLLSTREDVWGEIRLIASPRSAGRKLACRGEQLEVVALSEEAFEGIDVAMFDVPDEVSAQWAPIAAAKGAVAVDNSGAFRMDPQVPLVVPEVNASAARNRPKGIIANPNCTTLSMIVVLGALHQRYGLASVVAASYQAASGAGQPGIDTLRAQMEKVSGTNLGTHPGDLRGVVGDLGPFPAPLALNVVPWAGSLKEDGWSSEELKIRNESRKILGLPNLRVSATCVRVPVVTTHSVSVHASFEDEVTVAGAHEILRAAPGVVVLDDPAAGEFPTPADVVGTDPTWVGRIRRTLDDPKSLELFVCGDNLRKGAALNTAQIAEVVAAELSGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q668</accession>
    <name>C7Q668_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YD repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3166"/>
    <dbReference type="EnsemblBacteria" id="ACU72074">
        <property type="protein sequence ID" value="ACU72074"/>
        <property type="gene ID" value="Caci_3166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3166"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000662_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982822" evidence="2">
        <location>
            <begin position="33"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="3">
        <location>
            <begin position="2382"/>
            <end position="2408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2430"/>
            <end position="2455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2542" mass="265185" checksum="5EA6A35330F4221C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q672</accession>
    <name>C7Q672_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787371.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3170"/>
    <dbReference type="EnsemblBacteria" id="ACU72078">
        <property type="protein sequence ID" value="ACU72078"/>
        <property type="gene ID" value="Caci_3170"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3170"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_2_1_11"/>
    <dbReference type="OMA" id="VCFEGTV"/>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="170"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="489"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="527"/>
            <end position="534"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="801" mass="84770" checksum="9540D8B90EB74434" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q680</accession>
    <name>C7Q680_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72086">
        <property type="protein sequence ID" value="ACU72086"/>
        <property type="gene ID" value="Caci_3178"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3178"/>
    <dbReference type="HOGENOM" id="CLU_2697836_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="8009" checksum="0622A8143C5D47FF" modified="2009-10-13" version="1">MVYVVYLQGGPEPLGVRTDNRVVTTTEAVPEMKVPCEGGVGLWRYAEEHITIGTGQAAVFEFVRMEDEDPAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6A3</accession>
    <name>C7Q6A3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_3202</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3202"/>
    <dbReference type="EnsemblBacteria" id="ACU72109">
        <property type="protein sequence ID" value="ACU72109"/>
        <property type="gene ID" value="Caci_3202"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3202"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_463602_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981435" evidence="10">
        <location>
            <begin position="36"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="11">
        <location>
            <begin position="36"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="12">
        <location>
            <begin position="485"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="227"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU72109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="588" mass="58154" checksum="7EB3C815C675FA8E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6M4</accession>
    <name>C7Q6M4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5200"/>
    <dbReference type="EnsemblBacteria" id="ACU74059">
        <property type="protein sequence ID" value="ACU74059"/>
        <property type="gene ID" value="Caci_5200"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5200"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_11"/>
    <dbReference type="OMA" id="RVWAVDP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="26758" checksum="20753337FDDFBF5B" modified="2009-10-13" version="1">MNSTTKQTENAGRVPAGAWSGNPVAVITGASQGLGLALARGLAERGWSLVIDARTADRLAAAHAELAALTTVVALSGDVTDDAHRADLAEAASELGGASLLVNNASSLGGSPLPALAHFPLAALEQTFAVNVVAPLALTQLLLPQLRQHGGEVVNISSDAAVEPYEGWGGYGASKAALDHATAIFGLEEPQVRIWAVDPGDLQTQMHQDAFPGEDISELPLPATVVPAFLRLIDERRPSGRYQASDLLPRSAAADVEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6W2</accession>
    <name>C7Q6W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795703.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7146"/>
    <dbReference type="EnsemblBacteria" id="ACU75975">
        <property type="protein sequence ID" value="ACU75975"/>
        <property type="gene ID" value="Caci_7146"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7146"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="WIMQPRP"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="34518" checksum="5FE27170C574F1B0" modified="2009-10-13" version="1">MERLELRHLRTLCAIADTGSLRRAAAAQGYSQPALTTQLQRIEQYFGEPLFARSSIGVVPTAVGGEIVAQARDVLARMDAIGPRGHRSDDECRTVRLAATNTAMLSGLVTRFRDAAPQCSVTVSSVYSSKEMVGMLEEGLVDIAIGVDYPGQELRHSSIVAHRGIVTEPSFVAVPAGHPLAAHREVCLTDLADDAWFLTPDDGAGWPGVFFTACEVAGFRPATVHEFLGDRRQLHAMIAAGLGVAVVQATFETTAEVAVRPLIGSPLWCRYLLAWRVSAVSDDVVDTVYRSASEAYRDLVADAPHLRDWAARAYGFPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q734</accession>
    <name>C7Q734_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NPCBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795775.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7218"/>
    <dbReference type="EnsemblBacteria" id="ACU76047">
        <property type="protein sequence ID" value="ACU76047"/>
        <property type="gene ID" value="Caci_7218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7218"/>
    <dbReference type="HOGENOM" id="CLU_982425_0_0_11"/>
    <dbReference type="OrthoDB" id="2002435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM" evidence="3">
        <location>
            <begin position="176"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="27670" checksum="37E53DFA6BEEB35A" modified="2009-10-13" version="1">MTDPYDSSGPGGGSPGGPDQEGSGGGVGAMDHVRAAWQTPGGKMLAVIPAVVALILGGAAGAALGGGGGSKKPEIVSAPGPTDFVTVTATGTSSAGSDGSGAGSSGSTTASGTGTPTGTPTGSAASLPSTNPTQIGVVPLADLTPASGPWRSRNASPMLNGALQQFAIIQDLEDANTNGDVGYNLGRYYTKFTGVIGLDDNSPKSTLHPTIEIDGDGLKIATFTPTLGHPAQISLDVTGVLRLDVKYTSLDSDGNDSVAGSLVLGNGQLTTVPGYHPPAPSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7L0</accession>
    <name>C7Q7L0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3296</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787496.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3296"/>
    <dbReference type="EnsemblBacteria" id="ACU72203">
        <property type="protein sequence ID" value="ACU72203"/>
        <property type="gene ID" value="Caci_3296"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3296"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_0_11"/>
    <dbReference type="OMA" id="RMRIGMA"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="26342" checksum="93F0301E33A03422" modified="2009-10-13" version="1">MANTAGKFGPYPAPVLTAPVRSTGTSSSTAAARLPVRQQTGAELIRSRIALRVRLGVLASGERLPDTGVIAEELGMSEMTVRRALETMCQDGLLDRRRGRVGGTFVATNWDAVIEAFRDADQAASLEDFHLLLECGLVARSAGELPPDWASGLQAVVEEMNATVDHAELLRLETCFHLGLAEALGNGMAGEEVADLLGRLCLLATVPDAGRLQEANKHHADLLTALELGRLDAAVGAVKAHCLAATSPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U1</accession>
    <name>C7Q7U1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3378"/>
    <dbReference type="EnsemblBacteria" id="ACU72284">
        <property type="protein sequence ID" value="ACU72284"/>
        <property type="gene ID" value="Caci_3378"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3378"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_4_11"/>
    <dbReference type="OMA" id="HYALCEL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="121"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="179" mass="20058" checksum="E4CCAF3003CA29D3" modified="2009-10-13" version="1">MGAEHADWTADAFMAELFRVHSGPLLRYLLRLTLGDAARAEDLLQETMVRIWRHPEHFGGDVEALRPLVFTVARRAAIDAARARGARPAEVCEVDEAGSDTFGAEEPEFERVLLAQVVRRALLKLSPEHRAMIIEVHFNGRTIEETAHLLGIPLGTARSRTYHAARNLRQALTDLGFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q892</accession>
    <name>C7Q892_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795808.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7251"/>
    <dbReference type="EnsemblBacteria" id="ACU76080">
        <property type="protein sequence ID" value="ACU76080"/>
        <property type="gene ID" value="Caci_7251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7251"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="TYYAPIP"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="30580" checksum="B5305E9D56438E72" modified="2009-10-13" version="1">MKAVRFSRFGGPEVLELVELPDPHPGPGEVRIAVRAAGVNPSDWKKRRGLMDEELPQTLGYEAAGVVDEVGAGVEDVAVGDRVVGFSMAGAAQAELAVLTYYAPIPAPLDFVGAAALPAAVETATRALDQLGVKNGSTVLINGASGGVGSASVQLAVVRGARVIGTASPANHDYLRSLGAEPVAYGEGMSERVRALAPDGVDLALDAAGSGVLAELIELAGGAENVLTIADFAGAQEHGVRFSRGDSGRALHALADVGPLIEAGRFSLPVAQSFPLAEVAEAQRVSEDGHVRGKIVLVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B7</accession>
    <name>C7Q8B7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Benzoate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7276"/>
    <dbReference type="EnsemblBacteria" id="ACU76105">
        <property type="protein sequence ID" value="ACU76105"/>
        <property type="gene ID" value="Caci_7276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7276"/>
    <dbReference type="eggNOG" id="COG3135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041268_2_0_11"/>
    <dbReference type="OMA" id="MTSQNMP"/>
    <dbReference type="OrthoDB" id="1456447at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042925">
        <property type="term" value="F:benzoate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004711">
        <property type="entry name" value="Benzoate_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30199">
        <property type="entry name" value="PTHR30199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03594">
        <property type="entry name" value="BenE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00843">
        <property type="entry name" value="benE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="434" mass="43340" checksum="639A03809CD02EA3" modified="2009-10-13" version="1">MGGEQGGGVGAAGVEVEDAVVAVGGGDGGDTDRSRGDDGLGPTFGAGVVTALVGFTSSFAVVIAGLRAIGATERQAASGLLVLSVSMGVAGVVFSVRHRMPISIAWSTPGAALLVSIGAGRVHSGHGGASGYREALGAFALAGLLIVITGFSRTLTRWIATIPAAISAAMLAGVIAPICFESAQAAVRLPRLALPALAVWVVLGRFAKRWATPAALAAAFIGLALDPSTRGHLTGGLLPTLTATTPRLDIGTLISLGLPLYLVTMASQNLAGIAVMRSYGYEPPIREVLMGTGAATALGAPFGGIAINFAAITAALAASPDAHRDPRRRWIAATTAGVLYVVLGLAAAAATALLIAAPPLLIEGVAGLALLPALGGALTTALSDIRYREPATAAFVTTASGITVAGIGAAFWGLLIGLALLVTSQFRRHQVNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8U0</accession>
    <name>C7Q8U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785649.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1432"/>
    <dbReference type="EnsemblBacteria" id="ACU70355">
        <property type="protein sequence ID" value="ACU70355"/>
        <property type="gene ID" value="Caci_1432"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1432"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_0_11"/>
    <dbReference type="OMA" id="AFFCANN"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="34565" checksum="23554677D980047A" modified="2009-10-13" version="1">MADVARVAGVSLKTVSRVVNNVPTVDSQLVAKVDAAVAELGFRRNDMARNLRAGGSSATVGLLIEDLANPFYAGIAAAAAQYALDRDTLLITASSEEDVDRERKLLLELCARRVDGLLVVPAADADHVYLRPEIERGTPIVFLDRPPRNLRADTVLIDNAAGARTGIEHLVAEGHTRIGVVADWLSISPMAERLGAAEKALEQAGLPYRPDLITSGVHTVRDATAAVNAMLDGPEPPTAVFALNNRLVLGALSAVRGRAAEVELVGFDDFETAAFVPWPLTVVSYDVREIGRIGAELLFNRIAGDRSRPKTVVVPTELIVRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C8</accession>
    <name>C7Q9C8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794003.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5415"/>
    <dbReference type="EnsemblBacteria" id="ACU74274">
        <property type="protein sequence ID" value="ACU74274"/>
        <property type="gene ID" value="Caci_5415"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5415"/>
    <dbReference type="eggNOG" id="ENOG5032TBA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072020_0_1_11"/>
    <dbReference type="OMA" id="FRYHIVS"/>
    <dbReference type="OrthoDB" id="1520742at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021522">
        <property type="entry name" value="MctB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11382">
        <property type="entry name" value="MctB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="32793" checksum="BD1F499456022B26" modified="2009-10-13" version="1">MIDFRYHVVSIVAVFLALTVGLVIGSSYLSKVAYDELNNQLASLRSQNQALHGTQNELSAQVRDRNSLIAALGPDAVAGKLAGHSVAVVILPGADGSSGDAMADLLAKSGAVVTGEVTLKSALLDPGQAGKLAAAGAKLPADERGGEQLTSPSSSASGATPSPVIALADIAGAVVHRIPASTSGIGEQHITDQASQDVLTAYSDAGFLDVKSASTSSADLVVVMSPAAPSSGSAANDAADALYLGFLKDLTGGGRSLGAVLAGPASSAASPGLLAAAQKDSWVSKNVSTADTADQASGRIITVFALAEAASGKTGHYGLTGTADGPLPDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9F5</accession>
    <name>C7Q9F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794030.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5442"/>
    <dbReference type="EnsemblBacteria" id="ACU74301">
        <property type="protein sequence ID" value="ACU74301"/>
        <property type="gene ID" value="Caci_5442"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5442"/>
    <dbReference type="eggNOG" id="COG4848">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048417_0_0_11"/>
    <dbReference type="OMA" id="FDQAGPH"/>
    <dbReference type="OrthoDB" id="1244918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="44139" checksum="1AD76AB7C4FA7D51" modified="2009-10-13" version="1">MGIADRLFGSARDRFGKEVAARVRAVDAVARADYDPVEFQVVVQGARGGEPSIINLETVFRETQGAPAGVRRAAIGRLVDIAALPPTPDHWDDVRATLRPVLRPIPADPKFDLVSRPAGPYLSEMLVLDTPSAMRYAARTDLKRWEVSAEEAFATAHRNMARTVTTSLDEARRREGSAEPIRLTDNGDAYLTSLPLVQGWLATMHRLAGARPLAFPISNNTLLLAYETDDAAALAKAFEVAEREWRESARPISPAPLTVDDEGAVVLYQPAHDHPAHAAVKHAQILLAMDAYGPQTEYLRAIAGPGDPFPAALKGFRSPEGAEVTAASWADDETSLLPAADVVAFPKHNEKMLLIPWTVVAEEARLTPAEGYHPARYRVGEWPDADVMERMRKLAAEAAEAARGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9H5</accession>
    <name>C7Q9H5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tyrS</name>
        <name evidence="9" type="ordered locus">Caci_5462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794050.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5462"/>
    <dbReference type="EnsemblBacteria" id="ACU74321">
        <property type="protein sequence ID" value="ACU74321"/>
        <property type="gene ID" value="Caci_5462"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5462"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_0_3_11"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="230"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="45958" checksum="64471E6EEBFB80DE" modified="2009-10-13" version="1">MTDIVDDLKWHGLLALSTDEDALRKAFADGPVIFYVGFDPTAPSLHFGNLVQMIAARRLQEAGHTPLILIGGSTGLIGDPKPNAERTLNSKETVAEWVVRIRDQVSRFISFEGPNAARVVNNLDWTAPMSAIDFLRDIGKHFRVGKMLSKDAVSARLNSEAGISYTEFSYQVLQGMDYLELYRQYGCTLQTGGSDQWGNITAGVDLIHKAEGVSVHALATPLLLKADGTKFGKTESGTVWLSGDLMTPYAFYQFFLNSEDAMVISYLKVFSFRSREEIEELERLTMEKPQMRAAQKALAEEVTTLVHGAEATAQVIAASKALFGQGDLTELDEPTLRAALSELPGTKTAELVPVAQLLADTGLVVSRGAGRRTINEGGAYVNNRKIEAEDEAPTKEDLLHGRWLVLRRGKRTLGAVEVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9S5</accession>
    <name>C7Q9S5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_7418</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7418"/>
    <dbReference type="EnsemblBacteria" id="ACU76244">
        <property type="protein sequence ID" value="ACU76244"/>
        <property type="gene ID" value="Caci_7418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7418"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="HNISHGH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="543" mass="57084" checksum="51BE089C3B7C69C0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Y1</accession>
    <name>C7Q9Y1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796025.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7475"/>
    <dbReference type="EnsemblBacteria" id="ACU76300">
        <property type="protein sequence ID" value="ACU76300"/>
        <property type="gene ID" value="Caci_7475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7475"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_1_0_11"/>
    <dbReference type="OMA" id="IGVEYRD"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="28"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="22729" checksum="EF8A1903D6781B09" modified="2009-10-13" version="1">MTNTQKYTTTSPVSVNLDIPAGSVHLIAGDRTDTIVEVLPADSSKRRDVKAAQQIGVEYRDGVLSIAAADANRLLGSSGAVRVTIQLPTGSRLEGKAGAAELHSTGRLGEVSFDGGYGSVSVEEAASAYLTVHTGDVRISRLAGPAQIRNGKGDITIAEAHAGRVELHADMGNLSVAAAHGVSGVLDAGTASGRIANALYNAEGAAAALSIKATTSLGDITAGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAK6</accession>
    <name>C7QAK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="6">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792234.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3601"/>
    <dbReference type="EnsemblBacteria" id="ACU72505">
        <property type="protein sequence ID" value="ACU72505"/>
        <property type="gene ID" value="Caci_3601"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3601"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="TGVDVCC"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="38423" checksum="43EB32E8DAC47F65" modified="2009-10-13" version="1">MDIGEIARRAGVARSTVSYALSGKRPVSVETRRRIQQVIDELDYRPNASARALKEGRTRTVGLVIPPAGPRLTSMQLDFVGSVVEAAARVDLDVLLSPSGGDRDRSLERLISGRRVDGVILMEILMEDSRVARVAQSGVPFVTIGRVRDPDATWWVDMDYAALVGRCVDHLADLGHRHVALVNRSPALMAAGYSPGHRARDGFAEAVARRGVSGSEFCCEDDVAGGERCVAEILATRPSTTAIVTVNEAALPGVQRALERAGHEIPRTFSVAGIAAHQWAEEFHPPLTAADVPSLAMGTVAVELLAEHIADPDAPAGHRLFMPPISLRDSTGSVPRPSARPAFFSPAAPRRFREADAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL5</accession>
    <name>C7QAL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792243.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3610"/>
    <dbReference type="EnsemblBacteria" id="ACU72514">
        <property type="protein sequence ID" value="ACU72514"/>
        <property type="gene ID" value="Caci_3610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3610"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_1_11"/>
    <dbReference type="OMA" id="GHADETD"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="878"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="953" mass="102037" checksum="4BEF54CF0B3BE07E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAN7</accession>
    <name>C7QAN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794089.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5501"/>
    <dbReference type="EnsemblBacteria" id="ACU74360">
        <property type="protein sequence ID" value="ACU74360"/>
        <property type="gene ID" value="Caci_5501"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5501"/>
    <dbReference type="eggNOG" id="ENOG502Z9YN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049155_0_0_11"/>
    <dbReference type="OrthoDB" id="1197197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013494">
        <property type="entry name" value="CHP02678"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09661">
        <property type="entry name" value="DUF2398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="465" mass="50538" checksum="C0F0754E545C6370" modified="2009-10-13" version="1">MAEHLAAAGVIPSDLGSFQHAVRLVLTNDLITADRPRSGSLDVVLRWADRISVDMQELFAYTLIATARQVRLVRRNDVLDPTQHLIFTSRSGRQFDRRRLAYLCLVLAGFQRSRIEVSLVDIVKAVTPLANAQPSLGFEPTITEHRRAVVDVLDWLTDRGALRLSDGSLDAWAGGDREGDALYDIDHDVCGALFRPPAALQHVASAAQLMEGADGPNKSARREAATRRARRLLIEQPVVYFERCESAVAAALRSPDLAENLARLTGLVVERRAEGVMLADPSGRFTDRIFPLKGGAVNRTAGLILGAIANLLEDPNEARRLPRLPVPTLTEETADLVTRIDSARPLRDDDRPGRPQASVTDAEPNQLGLNAPFLSTAQVATIVDELYVEFGASSFTAIWQGDPTGLARAATRFLADLGLVHEIPGGLLVLPAAARYRNIQGVLPQPAPDGLFPLDFTENKDGTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAY9</accession>
    <name>C7QAY9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5603"/>
    <dbReference type="EnsemblBacteria" id="ACU74462">
        <property type="protein sequence ID" value="ACU74462"/>
        <property type="gene ID" value="Caci_5603"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5603"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052162_0_0_11"/>
    <dbReference type="OMA" id="YPTSVLY"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983082" evidence="1">
        <location>
            <begin position="42"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="69"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="38556" checksum="E73B187969707D72" modified="2009-10-13" version="1" precursor="true">MSSAISKKSAATKMLIVAAAGALSLTALSACSSSKSSSSSAASGTAGVSKTTQHVTLMVGGIDKQIYLPYKLADQLGFYKKYNVDVTLSTEQDGGVGAEEAMVSGQVDMAGAWYNHAIDFQMKHKNVEDLVQLSGAPGEREMCGNKATVHTGADFAGKTMGVTDLGSGTDTLTQLIAAQSGVAKNKFSRTGVGAGSTALAALKNGSISCVMTTQPTVTAIEKQNLGYSAIDLATTEGATKALGGAWPAAGVLARTDWANQHQEAVQDVVDALVATMHWISTHSATDIANALPASYTNNAIISKADYIAGLTMDKSQFLPDGIMPAGGPKVVLTTEKLIGNADDSVNLGATFTNTYAIKANQLEGFTTTTTPAGPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB57</accession>
    <name>C7QB57_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796073.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76348">
        <property type="protein sequence ID" value="ACU76348"/>
        <property type="gene ID" value="Caci_7523"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7523"/>
    <dbReference type="HOGENOM" id="CLU_1529904_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="19074" checksum="5940B8875059F4F5" modified="2009-10-13" version="1">MLWRVGDLSGVPEEVAGADVPVVVSFVSTARTAVVTELGDALATVLWVGVVVAAGCAAAFRDATVVLPVVSVLLVIAVALGHYRKLRVAGRLRPAPVTVAFDEDGVTYAVSGKIAKLPWLQWRRAYRRFGIWHLKLTAAPTRGLAFPDKVLEPEQRARLVDLLEDHNLLRNGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS8</accession>
    <name>C7QBS8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792276.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3645"/>
    <dbReference type="EnsemblBacteria" id="ACU72547">
        <property type="protein sequence ID" value="ACU72547"/>
        <property type="gene ID" value="Caci_3645"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3645"/>
    <dbReference type="eggNOG" id="COG4319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129336_1_1_11"/>
    <dbReference type="OMA" id="IPGRANI"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02246">
        <property type="entry name" value="TIGR02246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="16"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="15011" checksum="23DF79F495C287E6" modified="2009-10-13" version="1">MTQTVPETAADTAAVHALLDQLETAWAEHDAKKFADLFAPTGTVVLPGDILMDGRAHIQGFMTQAYQGPYKGTTVTGRALVTHFHSSEFAVMVTEGGVMAPGETEVAPERAIRATWVCVKIDGQWLLAAYQNSPLNLPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC15</accession>
    <name>C7QC15_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792363.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3732"/>
    <dbReference type="EnsemblBacteria" id="ACU72634">
        <property type="protein sequence ID" value="ACU72634"/>
        <property type="gene ID" value="Caci_3732"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3732"/>
    <dbReference type="HOGENOM" id="CLU_2823186_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="66" mass="6642" checksum="8FDB382DB5F35A15" modified="2009-10-13" version="1">MEVWDHENLLGGDDPIGDIRLGEVSAVWLRASLLAGDADGLAPSSLLDSGTATISPLTLAIGPSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC21</accession>
    <name>C7QC21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP oxidoreductase coenzyme F420-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792369.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3738"/>
    <dbReference type="EnsemblBacteria" id="ACU72640">
        <property type="protein sequence ID" value="ACU72640"/>
        <property type="gene ID" value="Caci_3738"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3738"/>
    <dbReference type="eggNOG" id="COG2085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076368_2_1_11"/>
    <dbReference type="OMA" id="HMAHWLE"/>
    <dbReference type="OrthoDB" id="1768241at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="9"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="21207" checksum="FB52218AB02ADF6A" modified="2009-10-13" version="1">MSTISTSSTISIIGAGNMARTLGTLAVAGGNTVEIIGRDQSKAAAVAKALGSGATTGEWGAVPAGDIVIVALLADAVAPTVAQYGDALAGKVIVDISNPFNAAADGLAYRGETSIAQEAAKVAPAGASVVKAFNTIFGHVLDKGGRPDVFFAGDDAQAKADVEVFIKSLGLRPLDVGGLHMAHWLEGAGLVVMGLARNGVGHWDLGLGVAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC82</accession>
    <name>C7QC82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794259.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5671"/>
    <dbReference type="EnsemblBacteria" id="ACU74530">
        <property type="protein sequence ID" value="ACU74530"/>
        <property type="gene ID" value="Caci_5671"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5671"/>
    <dbReference type="eggNOG" id="COG2223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040020_1_0_11"/>
    <dbReference type="OMA" id="IKWANLV"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="234"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="420" mass="44647" checksum="7E728545B7943FD3" modified="2009-10-13" version="1">MYLTGSRTAKRIQEARSTRERVPFNVKMLGTVSLLTDVSSEMLVAVVGYYLLNVLHETPTAIGFLDGLYNGIPALLAIPAAYLSDRWQRRKLLAGLGYGASAVTKLGFPIVGPSFGGLSGLLSADRFGKGMRSAPRDALISLSSPPQILGRSFGVHRMLDNIGAATGPLIASFVLLWTTKFGTERKAFDALFIIAFCVAAVGVVVFCLYVTDHKAELQERSAASLRAAGGLVRQSWFIRTGIAVALLGLAWVSDTFVYLTLAHRMALSASEYALLATGTMGMFVLMAIPVGRLADRVGRWKVFVVGHLLLVIAYALLATNVPNGFLLVAALLLPGIAYAATDGVLMAYCGPRIPAALRTSGLAVMQSIGAVAGFVSSVAFGAAWSHTDPKTVMLWFAGAMAVAITVSTLLVSPWKERADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH1</accession>
    <name>C7QCH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796159.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7610"/>
    <dbReference type="EnsemblBacteria" id="ACU76434">
        <property type="protein sequence ID" value="ACU76434"/>
        <property type="gene ID" value="Caci_7610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7610"/>
    <dbReference type="HOGENOM" id="CLU_2697842_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="7386" checksum="12813567D088ED41" modified="2009-10-13" version="1">MPDQASPTAPAALTLPHDALAPDLVALFLGATPHPDIVIPEPTVTIADLAAAARAGGPAPAGLRWDAARQRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCP4</accession>
    <name>C7QCP4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit I</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nuoI</name>
        <name evidence="8" type="ordered locus">Caci_7683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796232.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7683"/>
    <dbReference type="EnsemblBacteria" id="ACU76507">
        <property type="protein sequence ID" value="ACU76507"/>
        <property type="gene ID" value="Caci_7683"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7683"/>
    <dbReference type="eggNOG" id="COG1143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067218_4_0_11"/>
    <dbReference type="OMA" id="VDTPHAI"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="22357" checksum="29931282F1863AC3" modified="2009-10-13" version="1">MSDQQNPYSGKEKPKNPLAGVAGFGVTFSTMFKKRTTEQYPEEPKQTALRFHGRHQLNRHPDGLEKCVGCELCAWACPADAIYVEGADNTEEERYSPGERYGRVYQINYLRCILCGLCIEACPTRALTMTNEFELADSSRASLIYTKDELLAGLTEGMVESPHSIFPGMTAQDYYEGKVTAAAPGTVPQQRGSAKPDSDGEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCQ8</accession>
    <name>C7QCQ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796246.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7697"/>
    <dbReference type="EnsemblBacteria" id="ACU76521">
        <property type="protein sequence ID" value="ACU76521"/>
        <property type="gene ID" value="Caci_7697"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7697"/>
    <dbReference type="eggNOG" id="COG2162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049918_1_0_11"/>
    <dbReference type="OMA" id="YCFHLNG"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="32178" checksum="D2FD33E54F4D0851" modified="2009-10-13" version="1">MANIDVQGYLRRLGTEHPGKPTIEGLFALHRAHVERVAYTSLQVHLGQRTTPDPFDSAARIVAGESGYCYHLNGGFGALLETLGYDVTWHRGRVWSREPRGHGLGPVADEPNHMVLLVEAENTLYYCDAGLGDGLHEPLLCVPGETAQGPYTYKLERTRFDNGASGWSFTHDPKADSFTGMVFEERIAALPDFVARHEWMETNPESGFVKNLDVYRRDAAGVDHLRGCVLTRSDGTTVTKRDLTDSEEWFDALADIFALRLPGIGDVAQERLWKRVWEQHVAWSAEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS7</accession>
    <name>C7QCS7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796265.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7716"/>
    <dbReference type="EnsemblBacteria" id="ACU76540">
        <property type="protein sequence ID" value="ACU76540"/>
        <property type="gene ID" value="Caci_7716"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7716"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_5_11"/>
    <dbReference type="OMA" id="EAYIRAW"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="101"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="19081" checksum="C6EB7199177A4607" modified="2009-10-13" version="1">MGTARSEADFEAFYSASSRRLLGHVYAMVGDVAEAEDALQEAYARAWQRWGRVAGYEDPEAWVRTVAYRIAVSSWRRTANRLRAHRRGARAEEEPGASPDRLALIAALRAIPAEQRRVIVLHHLVGLSVEEVAQETGAPIGTVKSRLARGRRALAGHVSEFADENQEAENYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCT3</accession>
    <name>C7QCT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785937.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1722"/>
    <dbReference type="EnsemblBacteria" id="ACU70643">
        <property type="protein sequence ID" value="ACU70643"/>
        <property type="gene ID" value="Caci_1722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1722"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_11_0_11"/>
    <dbReference type="OMA" id="DYFWRSV"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981549" evidence="1">
        <location>
            <begin position="39"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="476" mass="49890" checksum="9302FB306C321CE0" modified="2009-10-13" version="1" precursor="true">MGAHSARSGNLRTLIAVGAAVAALVAGCSSSSSGSKPAAVNSADQPKNPTLVITANDIAGGKNSNEANWIQKTLIPDFVKAEAAKGITAHVTFRPNGVDDNAYKSKLALDLQSGTGDDVFSLDGIWVGEFADAGYVKPLNQVAGAQVDSWDGWSQITQAVQALGEYQGKRFGVPNGTDARVIFFNKKLFAQAGLPADWQPTSWQDLYDAAAKLKTLPGVTPVQWDGGVPMGEATTMQGFLPLLSGAGGSLWANGKWMKAGTAFTSALGFYQKIYGGGYGDPVLQEDAKGRDKSFTEFAANKIGIYAESDYMWRSVLNPTGGTAPMADRDTDVGYALIPSQTPSSGVKGQGFVSYSGGSDWSINPKTKYPQAAWDFLAFLNSKTETESRISGAPLLTARTDVNQQVLGNDPMLKFATDKVLPITAFRPSQAAYNDVSSLVQKAVADVVGGKSPEQAAAAYEKALEGLVGADSIAAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCW2</accession>
    <name>C7QCW2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease BN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785966.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1751"/>
    <dbReference type="EnsemblBacteria" id="ACU70672">
        <property type="protein sequence ID" value="ACU70672"/>
        <property type="gene ID" value="Caci_1751"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1751"/>
    <dbReference type="eggNOG" id="COG1295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045539_2_0_11"/>
    <dbReference type="OMA" id="PVRSPWI"/>
    <dbReference type="OrthoDB" id="1421045at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="38320" checksum="A43DCE95772BC61B" modified="2009-10-13" version="1">MRPVLDLPAGSGPDPDTVVPGQREQPEYAEQHNHLGLRERFRAQARNWWSVTRITFAICMRYRITGLAAEAAFFALLSLPPLAIGLAGTLGYLNGWIGAARIVEIKHHIEGAAGTMLSGPGVQKIDGLLTNLLANGHPELISIGFLLALWAGSRAMNVYVDTITIAYGLSGRRGIVRTRLLAFGMYMLGLLLGSVALPLLVIGPDLLVSALPPITDLIHAVYWPLMLTVLAAFLNTLYHLAVPVRTPWSQDLPGTVLALLLWLGGSALLRDYVSTTFSDTKSTNSLYGGLAAAVAILVWLYVTALAVLLGAALNAAVEQVWPSRRLWLARLALRQRVAAQRDATVPVPEGFPTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD96</accession>
    <name>C7QD96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3787"/>
    <dbReference type="EnsemblBacteria" id="ACU72689">
        <property type="protein sequence ID" value="ACU72689"/>
        <property type="gene ID" value="Caci_3787"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3787"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_1_11"/>
    <dbReference type="OMA" id="VSWICVI"/>
    <dbReference type="OrthoDB" id="1531811at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="115"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="33526" checksum="77D54C692FD57921" modified="2009-10-13" version="1">MPTTNIARRRSRSILPSPVQDDPWSLPGWTPSEGLSDSSETDRAETRQRRDGELRTKAGRRLLRCVSLGAAILAWQLLTTHQVTFWIRFGNLPSAGAVATDFRHQLGTAVYYQDIAASLLRILGGFLIAGLAGIGTGIALARSRFAEDILGPLLEVVRPIPAIALVPIAILAFPSNEQGMVFITATAAFFPILVSTRHAVRALPTVVEDAVRTLGAGRWTVLRRVVLPGALPGVFGGLSVGMGVAWICVISAEMISGQYGIGYRTWEAYTVVDYPSVVVGMLTIGLLGGATAAAVELAGRRVTGWLPRGTEGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDI6</accession>
    <name>C7QDI6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase class 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794339.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5752"/>
    <dbReference type="EnsemblBacteria" id="ACU74610">
        <property type="protein sequence ID" value="ACU74610"/>
        <property type="gene ID" value="Caci_5752"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5752"/>
    <dbReference type="eggNOG" id="COG3675">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_531787_0_0_11"/>
    <dbReference type="OMA" id="DNANMAY"/>
    <dbReference type="OrthoDB" id="446861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_3" evidence="1">
        <location>
            <begin position="82"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="329"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="2">
        <location>
            <begin position="422"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="512" mass="53247" checksum="3E67953B4C84123E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDJ2</accession>
    <name>C7QDJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5758"/>
    <dbReference type="EnsemblBacteria" id="ACU74616">
        <property type="protein sequence ID" value="ACU74616"/>
        <property type="gene ID" value="Caci_5758"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5758"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_601184_0_0_11"/>
    <dbReference type="OMA" id="KPWCAGI"/>
    <dbReference type="OrthoDB" id="480174at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="498" mass="53017" checksum="37F4298ECC37AD3B" modified="2009-10-13" version="1">MNCYQRNIYEALDNLRCKRLHCRHCVAVHQHAYDTGDMEGDHVFRSACLLAAAVAATTLMTACSNGSGGPGGSDDSGQTGAAAATLTGDCAQYQAYAGHAGKKVTMFASIISPESDSLQQSWKQFEDCTGITIQYEGSNDFESQLPVRVSGGNAPDLAVIPQPGLLAQMVASGQVAKPSAGTQANVDKYWNKSWKTYGTVDGTFYAAPMSANMKSLVWYSPKAFAAAGYQIPTTWEAMVALSNQVAASGKKPWCAGIGSGTATGWPATDWLEEVVLRKYGGAVYDQWVSHQITFSDPRIEDAMNTVAGWMQNPAWVNGGYGDAKTIASTSFQDAGKPILTGQCLMMQQASFYEPQWPKGTKVGPDGDVFAFYLPGISASVPTPVEGGGEFVTAFSSRPEVRAVQEYLSTPGWATSRIKVAPGWVSANTGVDPAVYTDPIDALSAKYLTDPKATFRFDASDMMPAAAGSGAEWTAMTAWFGEGKSVAQTAKAIDDAWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK6</accession>
    <name>C7QDK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acid phosphatase (Class B)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794359.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5772"/>
    <dbReference type="EnsemblBacteria" id="ACU74630">
        <property type="protein sequence ID" value="ACU74630"/>
        <property type="gene ID" value="Caci_5772"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5772"/>
    <dbReference type="eggNOG" id="COG2503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053338_3_0_11"/>
    <dbReference type="OMA" id="NSTHEPY"/>
    <dbReference type="OrthoDB" id="1535353at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005519">
        <property type="entry name" value="Acid_phosphat_B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014403">
        <property type="entry name" value="APS1/VSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03767">
        <property type="entry name" value="Acid_phosphat_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002674">
        <property type="entry name" value="VSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983124" evidence="3">
        <location>
            <begin position="34"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="27707" checksum="FE0E56573D93F0B6" modified="2009-10-13" version="1" precursor="true">MPISTVKRSSRTLVILAAVSAGALVAGGTMALADSAPRTDKQITNMTTEVANIEAYYGDTKDAAGEHWPSAQSNYAIQVAGIESKAEGYLADKSKHDKGAKKAIVLDVDDTSLSTYNYELETTFVYSPASNATYIATKTMPAVFGMNTLAAKAVAEGYTVFYITGRPESQRTYTEANLTAVGFPAATSANLFMKNAANPPSYLPCGATCTTDQYKSGTRAYLESQGYRIVANFGDQYSDLSGGHADHTYKIPNPMYFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDW0</accession>
    <name>C7QDW0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bioB</name>
        <name evidence="16" type="ordered locus">Caci_7724</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796273.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7724"/>
    <dbReference type="EnsemblBacteria" id="ACU76548">
        <property type="protein sequence ID" value="ACU76548"/>
        <property type="gene ID" value="Caci_7724"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7724"/>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033172_2_1_11"/>
    <dbReference type="OMA" id="AMGVHRY"/>
    <dbReference type="OrthoDB" id="940969at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="62"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU76548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="37068" checksum="8E35C05E334362ED" modified="2009-10-13" version="1">MTTTENDTENDLDILATARGQVLAEGVGLTEEQVLRVLRLPDEALPELLQLAHEVREKWCGPEVEVEGIVSLKTGGCPEDCHFCSQSGLFPSPVRAAWLNIPELVEAAKQTAATGATEFCIVAAVRGPDERLMKQMREGVKAIQDAVDIQVAASLGMLTQEQVDDLADMGVHRYNHNLETARSHFPNVVTTHSWEERWDTLTMVRDAGMEVCCGGIVGMGETLEQRAEFAAQLAALTPDEVPLNFLNPRPGTPFGDMEPLSSQEALKTIAAFRLALPRTILRYAGGREITLGDLGTEQGLLGGINAVIVGNYLTTLGRSPQEDLALLTKLEMPIKELSKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEF8</accession>
    <name>C7QEF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786142.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1929"/>
    <dbReference type="EnsemblBacteria" id="ACU70849">
        <property type="protein sequence ID" value="ACU70849"/>
        <property type="gene ID" value="Caci_1929"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1929"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_2_11"/>
    <dbReference type="OMA" id="WLISRAF"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="16537" checksum="EA5ABF994A3C6C18" modified="2009-10-13" version="1">MPAHHDRISRAPDRIKDRPTWLISRAFARSSALLSSGFEAHGAGLRSHHYRLLAALEQSGPASQADLGRDTGIDRSDVTAALAELEARRFVDRKVDPRHRRRNVVTLTTEGADELRRLDAVLDDIQAAVLAPLTDAEQRLFLDLLSRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEL2</accession>
    <name>C7QEL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792511.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3894"/>
    <dbReference type="EnsemblBacteria" id="ACU72782">
        <property type="protein sequence ID" value="ACU72782"/>
        <property type="gene ID" value="Caci_3894"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3894"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_14_2_11"/>
    <dbReference type="OMA" id="NIERQPI"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="10"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="58197" checksum="9C2AEDB0D0BD9047" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEY1</accession>
    <name>C7QEY1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5881"/>
    <dbReference type="EnsemblBacteria" id="ACU74739">
        <property type="protein sequence ID" value="ACU74739"/>
        <property type="gene ID" value="Caci_5881"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5881"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030169_3_1_11"/>
    <dbReference type="OMA" id="VECHSIM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="475" mass="51531" checksum="D9001A4A070B2289" modified="2009-10-13" version="1" precursor="true">MPSPRPLLPRSTPAASGISSRSIAALLDRLEARSVECHSIMVVHRGHVVAEGWWAPYSAERPHLLYSLTKSFTAIAVGLAVADGLLSLDDRVVHVLPDHVPADVSEQASRITVHHLLSMTAGHATDSLTEAWEREPDDLVKGFLGLPFAAAEGTRHTYDNSTTFILARMVERVTGRGLPEFLDKRLFKPMGIDHAEWDRVRSGAAFGFHGLHLTTEAIASFGELLRRGGMWGDQQLVPRGWVELATRRHIDSEWILDGSDQADFSYGYGYQFWMSRHGYHGHGSFGQQCVVVPSHDLVVAVTAQGEAQKVLDAMWECLLPGVGHAGSDEDDEMLADRLRRLSLPPVPGSADPGRSASATLDASAEGSALPDGTTVIIDPTDGGWLVRFESLLDVEVGHGGWRESSPLGRPVVAAGAWQGSTFVADLYVVTTPHRVRLVLDTEAGTATATWSTVPLTGPRLELHVRSPLMTRPDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD8</accession>
    <name>C7QFD8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7892"/>
    <dbReference type="EnsemblBacteria" id="ACU76715">
        <property type="protein sequence ID" value="ACU76715"/>
        <property type="gene ID" value="Caci_7892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7892"/>
    <dbReference type="eggNOG" id="ENOG502Z93N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_570643_0_0_11"/>
    <dbReference type="OMA" id="INHFNQA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="474" mass="52649" checksum="6AC291A08DB00F08" modified="2009-10-13" version="1">MVAAEDVLLFVNAATASTGQREFAQDAGQQTMSLSFLHEYMRVNYRELYAATMALGINDHNAALAIRGLLGDAKDVPTEQKAIEGRLIARTLLTLPPPRVFRLFKALRRDGVNNRRTRAIIRDWMTSLENPAYHAVKYRSGFKAGLKHAHVDISDSELRDFLFGPLQHKPYATPILETWRQAHYDGNVLYKLPYTVAEGFAAKRGVKREVFLERIGKQMTPLEKLRTDREPVDPLALLKGSAKYCGPQQIPWLTRLAIRILALPLDERAARRAELTDGMRHFARVEAGELAGTWGRVTAVLDDSFSSFGSPVKRRRPLAVALATHFLLEALAAPGQYTPLWMSGRDDPLLSYPGGATPLGTRLLDALDTSPERVVVVSDGWDNSPPGLAGEVLRVWRTRLDPARRVDIVHVNPVFDAEGLDVRALSPLVPSVGIRDAEDLVLLVELAQFAQGRVGLPELMAYLDGRVRRFLGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFG1</accession>
    <name>C7QFG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phytochrome sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7915"/>
    <dbReference type="EnsemblBacteria" id="ACU76738">
        <property type="protein sequence ID" value="ACU76738"/>
        <property type="gene ID" value="Caci_7915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7915"/>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_0_0_11"/>
    <dbReference type="OMA" id="MSPARTK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="86"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="647" mass="66746" checksum="8E2BDF83758B83FD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG03</accession>
    <name>C7QG03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2061"/>
    <dbReference type="EnsemblBacteria" id="ACU70980">
        <property type="protein sequence ID" value="ACU70980"/>
        <property type="gene ID" value="Caci_2061"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2061"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_7_11"/>
    <dbReference type="OMA" id="QAYEAYY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="14"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="105"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="22287" checksum="8E27361619F6F1A4" modified="2009-10-13" version="1">MAEEAESIDFAGFYTATATRVVGYLFVVLGSVAEAEDAAQEAYTRAWLRWSKVRGYEDPEAWVRTVGFRVAMSTWRKTRNRLSAHRTSGESGAHVPDLSPDRLVVVDALRRIPAEQRRALVLFHLLGLTVTEIAEEIGAPVGTVKARLSRGRKALAPYVSEFADDEEAPPGSAASSPASSPASSSLQALSSSEDSSALFGKKGMVSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG91</accession>
    <name>C7QG91_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792665.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4071"/>
    <dbReference type="EnsemblBacteria" id="ACU72936">
        <property type="protein sequence ID" value="ACU72936"/>
        <property type="gene ID" value="Caci_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4071"/>
    <dbReference type="HOGENOM" id="CLU_1425655_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="19700" checksum="F1A8EA28543F50CD" modified="2009-10-13" version="1">MSTDTEQTLTAWADALTEAGWTPQPNREVPAHLAGLRHLTDPAGAIEARAHAYPEDGIEVTLLSTARLPGGGAAWHVIAGWLSAEVVIAAAPAEGAEDAAVGQAVGDRLTAAGWTLQRFEVLGPSFAEYQWASPDDTRWATFTTPDPDPDGNGADGGWILSRPGDGGRQHRITASASTPAAAITALALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGC9</accession>
    <name>C7QGC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792703.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4110"/>
    <dbReference type="EnsemblBacteria" id="ACU72974">
        <property type="protein sequence ID" value="ACU72974"/>
        <property type="gene ID" value="Caci_4110"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4110"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="VKMTPVI"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="131"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="25000" checksum="EC06BDC8004BB081" modified="2009-10-13" version="1">MAAETPQKNRLLIVEDDTELATLLTALIEGEGFHVDTAHDAQRGLHLGLAHDYRVMVIDRRLPGMDGLDLVAGLRRRAVTARVLILTALGAHAERVRGLDGGADDYLTKPFDVHELLARVRALDRRFSDASDLLRLGEGYLDRQARDVALADGTRVALSGREFDLLDTLAARPRAIHSRSQLRATVFPDTAAESVVDTYVYYLRRKLGRQIVRTVYGLGYRIGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGX5</accession>
    <name>C7QGX5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796550.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8002"/>
    <dbReference type="EnsemblBacteria" id="ACU76825">
        <property type="protein sequence ID" value="ACU76825"/>
        <property type="gene ID" value="Caci_8002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8002"/>
    <dbReference type="HOGENOM" id="CLU_1500923_0_0_11"/>
    <dbReference type="OrthoDB" id="1601056at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="179" mass="18821" checksum="0471E1622E422EBD" modified="2009-10-13" version="1">MRVRLGGSRHTHARPAPALRLPAAYDLLDVPAAAGHRVLLQLERLGTPLGPVLTVQPAGPGHEPVSGSRLRFFVEAGTTASFLADLKDLGWDPDDTDIRTIGVVLAAETPLPPASSARWVRPPETMAAGTPLGKLEAPGSQGERLTGVLPPARLLLGALAHACRRAEGRRFLFAGCRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHE3</accession>
    <name>C7QHE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0127</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0127"/>
    <dbReference type="EnsemblBacteria" id="ACU69082">
        <property type="protein sequence ID" value="ACU69082"/>
        <property type="gene ID" value="Caci_0127"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0127"/>
    <dbReference type="eggNOG" id="COG0111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_11"/>
    <dbReference type="OMA" id="MPERPQA"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983140" evidence="2">
        <location>
            <begin position="19"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="120"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="35922" checksum="A00D1D7479BFC8F4" modified="2009-10-13" version="1">MAGRAAALLAMRPDVAQAAFPAALRTRLDAVVEIDHGLVVTDFAEPRARWALAGAEVLLTGWGCPPLDAEALDAAPNLRAVIHAAGSVKHHLSPDFWTRGILASSAADANAYPVAQFTLSVILLAGKRMFTMARHYAEGTYKPPSTSQRFGNVGRTVGVVGASRIGRLVLPMLAREGFEVLLADPTLSAAEAAALMPAPWAVELVELDELLRRSDVVTLHAPSLPETHHLLDDRRLGLMRDGSVLVNTARGALIDTEALVRCCAAGRIDAFLDVTDPDEPLPPGHPLFLLPNVVVTPHLAGAMGSEIALLGAYAVADVERYAAGLPLLGGVHQDDLARIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHM6</accession>
    <name>C7QHM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2132</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786344.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2132"/>
    <dbReference type="EnsemblBacteria" id="ACU71051">
        <property type="protein sequence ID" value="ACU71051"/>
        <property type="gene ID" value="Caci_2132"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2132"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="PAAWMNN"/>
    <dbReference type="OrthoDB" id="618655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="17"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="52147" checksum="6F92040F79D7A6A6" modified="2009-10-13" version="1">MGTVTEHGKLFIGGSYVDPATTAKLEMISPVTEEVFGRTPEASPADMDRAVAAARHAFDEGPWPRMAVAERVEILRRLRDRYEARADELAKLISSETGSPYSWSILAQVWAPIMIWDYFLGLATEYPWEELRQGMLGPTIVRSEPVGVAAGIVAWNVPQFITVSKIAPALVAGCAVVVKPSPETALDSYLLADMALEAGLPEGVLNIVPAGRENSAYLAAHPGLDKIAFTGSTAGGKAVLAAAGANLTRVTLELGGKSAAIILPDADLSTAIPGLLPNSYMNNGQACVAQTRVLVQRDRYAKTVEAMAEAVKALRTGDPLDPETQIGPLVAERQRDRVESYIAKGIGEGARVVVGGGRPADLPKGWFVEPTLFADVDNRMVIAQEEIFGPVVAMIPYTDEADAVRIANDSDYGLSGSVWSADVEHGLDVARRVRTGNYGVNTFGMEFNSPFGGFKQSGVGREFGPEGLRAYLETKTVHLPSGYTPEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHP1</accession>
    <name>C7QHP1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786359.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2147"/>
    <dbReference type="EnsemblBacteria" id="ACU71066">
        <property type="protein sequence ID" value="ACU71066"/>
        <property type="gene ID" value="Caci_2147"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2147"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090900_0_0_11"/>
    <dbReference type="OMA" id="YEGWAPH"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="22131" checksum="72D2574149B4D5EE" modified="2009-10-13" version="1">MDHTLRAAAEAAPGFMPADEGLALYEAAERAAKVGDLLEIGTYCGKSTIYLAAAAATADRVVVTIDHHRGSEEQQPGWEYHDPKLVDPEVGLMDTLPTMRRTLHAAGVEDRVIAVVGRSPAVARLWNTPVGLCFIDGGHTDEHAQGDYEGWAHHVAPGGLLVIHDVFPDPEDGGQAPYRIYLRALESGDFVEDSVTGSLRVLRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV6</accession>
    <name>C7QHV6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2212"/>
    <dbReference type="EnsemblBacteria" id="ACU71131">
        <property type="protein sequence ID" value="ACU71131"/>
        <property type="gene ID" value="Caci_2212"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2212"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="RTHAEIT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30219" checksum="3443FFF76720652D" modified="2009-10-13" version="1">MSSAAGTPWSDPVTTPPREGAVDAASRIDTSKPHSARIYDYWIGGKQNFPADREVADKIAEAVPIVSMLARANRAFLGRAVRYAAEQGVKQFLDIGAGLPAAGPTHEVAQSVHSDASVVYVDNDPLVTVHGRALLADEARTRVFEGDLRDPKAILTHPDVAALIDFDQPVALLMVAVLHFFPDSADPAGVIATLTENLAPGSHLVISHAGSDLLPTDQEKLQVYNKAAEGAARDHAQITAFFQGFDLVDPGLVRVPAWRPTEELPADIDQYWMYGGVGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHX6</accession>
    <name>C7QHX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4157</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792750.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4157"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73021">
        <property type="protein sequence ID" value="ACU73021"/>
        <property type="gene ID" value="Caci_4157"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4157"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030937_0_0_11"/>
    <dbReference type="OMA" id="INALRYP"/>
    <dbReference type="OrthoDB" id="620389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980997" evidence="3">
        <location>
            <begin position="37"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="511"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="607"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="719" mass="72966" checksum="D6AB690216F9CA1F" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB0</accession>
    <name>C7QIB0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794716.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6133"/>
    <dbReference type="EnsemblBacteria" id="ACU74987">
        <property type="protein sequence ID" value="ACU74987"/>
        <property type="gene ID" value="Caci_6133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6133"/>
    <dbReference type="eggNOG" id="ENOG50329XM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113711_1_0_11"/>
    <dbReference type="OMA" id="EHEPNRG"/>
    <dbReference type="OrthoDB" id="1793636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014487">
        <property type="entry name" value="DUF3151"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11349">
        <property type="entry name" value="DUF3151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017349">
        <property type="entry name" value="UCP017349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="14568" checksum="90544E00688C5957" modified="2009-10-13" version="1">MHNDLLGAPSPTLLPDDAPVRDALAAGTDPAEVAAAHPAVPAAWAALAEGALAADDSTFGSVTAYAFARTGYHRGLDLLRRAGWKGHGPVPWSHEANRGFLRALNALGLAAERIGETEEAERCATFLGDSDPEAFKALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE9</accession>
    <name>C7QIE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794755.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6172"/>
    <dbReference type="EnsemblBacteria" id="ACU75026">
        <property type="protein sequence ID" value="ACU75026"/>
        <property type="gene ID" value="Caci_6172"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6172"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_5_1_11"/>
    <dbReference type="OMA" id="DHERAGH"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18937" checksum="DFF98E8A3486720A" modified="2009-10-13" version="1">MSQPSTLDDTDRRIVHLLQQDGRMSMRDLAAAVHVSRAHVYTRVKRLLDEGVIRRFTIQVDPERVGFSTSAYLTMKVEQNSWRQIRDTLAALPWVEHVALVSGDFDVLLLVRSASNKTLRDLVFTHIQNMPGVRSTRTLLVFDETDHLPALPGDPELIRESDPPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ3</accession>
    <name>C7QIJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794799.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6216"/>
    <dbReference type="EnsemblBacteria" id="ACU75070">
        <property type="protein sequence ID" value="ACU75070"/>
        <property type="gene ID" value="Caci_6216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6216"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_23_0_11"/>
    <dbReference type="OMA" id="VQTTVAY"/>
    <dbReference type="OrthoDB" id="1210653at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="41304" checksum="4AD64E9F4722CBB1" modified="2009-10-13" version="1" precursor="true">MGFALLLATAGGLSVANVYYAQPLLEQIGGALHVSAGSLGLTTGVTQLGYLVGLILLVPLGDLVDQRRLISWLTLVAGVGLAGAGFADGPVEFFAACAVVGLASAVVQVIVAYGAVLSPVEQRGRVIGVVTSGVVLGILLARTVSGLVAAALGWRAAFLLPAVLMVVMAVTVNRLLPRRRRAVAASVSYLRLISSVFTLTARDRVFRTRSLLALFLFGCFGALWGSVALPLSAAPWQLSTSQIGLFGIAGAAGALSASGAGRLADRGRAPVVTGVTLVLLLLSWAAIGAAPFSLTLLTLGIVVLDFAGQALHVTNQHLIVAGDPAATSRVIGGYMVYYSIGTGGGAIVATSLYSAYGWGAVCSFGAALAVLALVVWSLDLLPEATRGVRARGSHTGACATGNVGRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIK6</accession>
    <name>C7QIK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794812.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6229"/>
    <dbReference type="EnsemblBacteria" id="ACU75083">
        <property type="protein sequence ID" value="ACU75083"/>
        <property type="gene ID" value="Caci_6229"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6229"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045983_2_0_11"/>
    <dbReference type="OMA" id="FAWPAAR"/>
    <dbReference type="OrthoDB" id="1086535at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981011" evidence="3">
        <location>
            <begin position="25"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="36685" checksum="E120DA58B3C6D92F" modified="2009-10-13" version="1" precursor="true">MRHLTRPTGVALAAIGIQALMVFAFTAPTVHNAPHRVPLAVSAPAPARGAVELRLEQAAPGAFAVHEVADEGAARAALADREAYGAVVVTTQGPHMLVASAASPTVATLLTQVGSHLAATGSDSSAQVTDVVPASAADPHGAAFTSMVLPLVMSALIGGVLLTIKLPRLRERVLATLLFALGGGTAVTLIASHALGFLPGSFLPVAASIAVPILAISAFSIATASLIGRYGFALAGAIMMLLSNPLSAASSAPQLLPTPWGRIGQDLPAGAAATLIRSTAFFHGHGAGHAEVVLGVWVAAAAAMMAAAGVRGWLRTRTHADHGTHAGHGTHTSHGAHAAHAAHPGRGAEVAEVVSLTAARGTSGVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ09</accession>
    <name>C7QJ09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0196"/>
    <dbReference type="EnsemblBacteria" id="ACU69151">
        <property type="protein sequence ID" value="ACU69151"/>
        <property type="gene ID" value="Caci_0196"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0196"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_859678_0_0_11"/>
    <dbReference type="OMA" id="ISTDETP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="33465" checksum="6988A45D23D4A3DC" modified="2009-10-13" version="1">MPPQDWAPPMPPQQDRVPPMPQPDRGPYPQFTQQPPPPQFTPPQMPGMPYPDEEPPPRKNTGRIIAGVVAGVVLLGGAGGIYLLTKGDSKKDTKPQPVAAATSATTPATTPAAPGTPASSGATSFPNNSYTGSAAAPPASASSTGGGATLDNAATDKTPFTAQALVAQSFTDDKNVAYALKSAQPQPCAKVGDAAVQTIVKSAKCTDFMAASWIDPANSRIVVSAMVIPYQDAATATAIYKKLSTTHTGDYAQWCPPAGQPGADTCAKLAKAGAVTREGKFGSFHRYVLITTAVYADLRNDDSQKDWLTSAAHGAFQNTLPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJB6</accession>
    <name>C7QJB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784553.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0305"/>
    <dbReference type="EnsemblBacteria" id="ACU69258">
        <property type="protein sequence ID" value="ACU69258"/>
        <property type="gene ID" value="Caci_0305"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0305"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_0_11"/>
    <dbReference type="OMA" id="MDHLWST"/>
    <dbReference type="OrthoDB" id="2027769at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14129" checksum="501B8A867B2E4679" modified="2009-10-13" version="1">MANERAGGPPRLGELERAVMDVLWNAPDGSTAQEIVERLAARDGTAELAATTVLTVLDRLRRKDFVERERVGRAHRYRAARTRDDVIAASMLAVLETTDDRRSALVRFAGSVSAEEAALLREALAGLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJF6</accession>
    <name>C7QJF6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4328 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2261"/>
    <dbReference type="EnsemblBacteria" id="ACU71179">
        <property type="protein sequence ID" value="ACU71179"/>
        <property type="gene ID" value="Caci_2261"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2261"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1812299_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025565">
        <property type="entry name" value="DUF4328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14219">
        <property type="entry name" value="DUF4328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4328" evidence="2">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15731" checksum="8CE4D128D0B42D2F" modified="2009-10-13" version="1">MPDAREACRARRGRKNAGLWGPQRRSQGWTIGGWFTPVVNLWFPMQIMQDVWRASDTEPNGSAGLGRVAAGWWTCWILAWLTGYRTFTARSTAPDGTRVVAEQASFFLDSTVVSALCLAVGAVLMRRMIVLITAMQRARGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKA1</accession>
    <name>C7QKA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794904.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6321"/>
    <dbReference type="EnsemblBacteria" id="ACU75175">
        <property type="protein sequence ID" value="ACU75175"/>
        <property type="gene ID" value="Caci_6321"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6321"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="WIAHATI"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="131"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="40063" checksum="574CE534BA6103BF" modified="2009-10-13" version="1">MSLPDVFDPDILALPLYDDAHRALAGDIGRWCAGRAEAWATLDAAEPAASGRALLADLGGAGWLRHLDPAEPASDLRALCLRRQALAYHEDLADFAYSIQELTAAAITRYGNETQQRCYLPGLATGTTAGALALSEPGAGSDLAAVALEAVADGDGFVLNGTKTWIAQGDIADVCVVLARTGDGPGPLGLTAFLVESSVPGFKAEPIGAIAPRSWAQLDFTDVRVGGEAVLGERGQGFVVALDILERARATVAAAAIGFARRAFRLALEHARTRKVYGGRLADLQLVKSSLARMDVKLSAASLLTARAAWAIDGDLDHAKHSSIAKLHSTEAAGEIVDGAVQIFGAAGLVAGSTVERLYRQIRSLRIYEGASEVIEMTIADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ0</accession>
    <name>C7QKQ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemA</name>
        <name evidence="17" type="ordered locus">Caci_8326</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796874.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8326"/>
    <dbReference type="EnsemblBacteria" id="ACU77149">
        <property type="protein sequence ID" value="ACU77149"/>
        <property type="gene ID" value="Caci_8326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8326"/>
    <dbReference type="eggNOG" id="COG0373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035113_4_0_11"/>
    <dbReference type="OMA" id="FAFKCAA"/>
    <dbReference type="OrthoDB" id="1358620at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="16">
        <location>
            <begin position="6"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="15">
        <location>
            <begin position="183"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="14">
        <location>
            <begin position="320"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="49"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="191"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU77149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="440" mass="45517" checksum="791F284F46476D3A" modified="2009-10-13" version="1">MSLLAVGLSHRSAPHALLERAALSTERTGKLLADLAASPNVHEAAALATCNRIEVYAGVEKFHAAVTEITELLSVHTGVAPAELTQHLYVHYDGRAVQHLFTVACGLDSMVVGEPQILGQIRTALATAQEHGTAGRALNDAMQQALRVGKRAHSETGLDRAGQSVVSVALEAAYAALGVEGPDDLRVLIIGAGSMAALAAASLNRAGVRHMVVANRTHERAEHLAAQYGGVAVPMAQIAPALAEVDLVVACTGAPGYVITGDMLERSAPGRPVALVDLALPRDVDPAVRELAGVHVVDLERVAQDGSAQAAGAAQEIGAVRDLVLGEVEAYASAQRAEAVAPTVAALRVMAADVVRAELERLRGKTPGLGDKDRAEVEQTVRRVVDKLLHVPTVRVKQLAGAPGGSSYAEALRELFGLDPASVEAVSAANAAGTTNEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB0</accession>
    <name>C7PVB0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mov34/MPN/PAD-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0313</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784561.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0313"/>
    <dbReference type="MEROPS" id="M67.009"/>
    <dbReference type="EnsemblBacteria" id="ACU69266">
        <property type="protein sequence ID" value="ACU69266"/>
        <property type="gene ID" value="Caci_0313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0313"/>
    <dbReference type="eggNOG" id="COG1310">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116765_1_1_11"/>
    <dbReference type="OMA" id="GAHYVLV"/>
    <dbReference type="OrthoDB" id="1811367at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070122">
        <property type="term" value="F:isopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="15641" checksum="B260ECFA34173A88" modified="2009-10-13" version="1">MLTVSQEIYDAIVAHARRDHPDEACGIVAGPEGSDRPERFVPMANAERSPTFYRLDPAEQFKVWREMDDRDEEPVIVYHSHTSTEARPSRTDISYASEPNAHYVLVSTRDTDKLGDFQFRSFRIVDGEVTEEPVTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVC5</accession>
    <name>C7PVC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784576.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0328"/>
    <dbReference type="EnsemblBacteria" id="ACU69281">
        <property type="protein sequence ID" value="ACU69281"/>
        <property type="gene ID" value="Caci_0328"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0328"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_18_5_11"/>
    <dbReference type="OMA" id="TMPWGNR"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15155" checksum="F269B8598EC1BA3F" modified="2009-10-13" version="1">MTTNLASTRIITADIASLVAFYEKATALPATWATPDFAELATPAGATLAIGSTRTVPLFAPDSAAPGANRSVIIEFLVDDVDALWQRLAAWIPASDVVAEPKTLPWGNRSLLVRDPDGTLVNFFTPVTPEARAKYGLSALIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI4</accession>
    <name>C7PVI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0387"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69340">
        <property type="protein sequence ID" value="ACU69340"/>
        <property type="gene ID" value="Caci_0387"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0387"/>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_0_0_11"/>
    <dbReference type="OMA" id="NLVNIMT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982227" evidence="1">
        <location>
            <begin position="34"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="42"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="32591" checksum="5605E7C8CE93E88C" modified="2009-10-13" version="1" precursor="true">MPRTVRKSLIAGAAFLLPAAAVGVAAGASTAAAATHAASFPAHYSAPYLQISSSDAKDMAADMAASGDKFYTLAFLTPKSGCTPEWEDGGDSVGAFSSQITALQNAGGNVIISFGGAEGGELAQTCTSVSSLEAAYAKVVSTYHVTRLDFDIEGSVLDNKTANSRRDQALAALQKANPAVQVDFTLPVDPTGLESNATALLSDAKSKGVAVNLVNIMTMDFGDGQNALKDAESGANATVPQLEKVFGVSSTKAWNMLGLTPIAGKNDDNENFTQANASTLESFAASKGVQELSFWEVDGYDKGVGYAYSKIFNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI9</accession>
    <name>C7PVI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784640.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0393"/>
    <dbReference type="EnsemblBacteria" id="ACU69345">
        <property type="protein sequence ID" value="ACU69345"/>
        <property type="gene ID" value="Caci_0393"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0393"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108923_6_3_11"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="17418" checksum="6DE8EC5BEA58CF05" modified="2009-10-13" version="1">MTTQKIQIERTYPAAPEKIWELWTTAAGIESWWAPEGFDVHVETLELKPGGALVYTMTAVGPDQVAFMEQVGLPLSTTSTKAFTEVEPVRRLAYTSLADFIPGVEPYDFLTEVELRPTADGGTHVVMTADAMHDEEWTGRLSAGRTNEMDNLGKVVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVN1</accession>
    <name>C7PVN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784682.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0435"/>
    <dbReference type="EnsemblBacteria" id="ACU69387">
        <property type="protein sequence ID" value="ACU69387"/>
        <property type="gene ID" value="Caci_0435"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0435"/>
    <dbReference type="HOGENOM" id="CLU_2492155_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="86" mass="8592" checksum="68B01C9039E468FE" modified="2009-10-13" version="1">MVASAHAKASIKVKLGWDQAGISDVGGVEGVGSVGSADRVEDADRVEDADSADDADDAGSDSSDGSAKAEDPAEDTAQDTAQDQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVS3</accession>
    <name>C7PVS3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786608.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2397"/>
    <dbReference type="EnsemblBacteria" id="ACU71315">
        <property type="protein sequence ID" value="ACU71315"/>
        <property type="gene ID" value="Caci_2397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2397"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_3_1_11"/>
    <dbReference type="OMA" id="WCSSEVC"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="145"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="191" mass="20472" checksum="F00FE81181593B33" modified="2009-10-13" version="1">MDPAPFRLDTGATWLNLLATRGSAFGRHPEERIPTPERFAEWLAAVELAPQTPTPVTAEDLDLARHLRETLRPLALSAATGEDPHQEAAGELIAFLAAHDEPLRVVAAAGVPGLDRPAPQDAAAALGRIARQAAEHLTGPERHALKSCPESDCRGVFADPDGRRRWCPSPACASRGRVRAHRARKAAVTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW08</accession>
    <name>C7PW08_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2482"/>
    <dbReference type="EnsemblBacteria" id="ACU71400">
        <property type="protein sequence ID" value="ACU71400"/>
        <property type="gene ID" value="Caci_2482"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2482"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_11"/>
    <dbReference type="OMA" id="FAKFMDP"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="28358" checksum="5B752C123C755EAC" modified="2009-10-13" version="1">MTLEAGKATAADGTAIAYQSAGSGTPLVLLAGQSNTHRWWDSARAAFQDAGHRTITLDWRGTGGSDKPDEPYSTRDFATDVVAVLDDLGIARARVYGTSMGGRVAQWLAADFPERVGALVLGCTSPGGAHAVERDRSVRQALASSDRVAADRYLLELMYTPDWLASHQGPYYVVGDPEMPAYAKGRHLTASGKHDAWDVLPTIAAPTLVVHGTDDVFNPTANAPLITERIPDARMVLIEGARHAYFDEFRDVAGPVVLDFLAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW42</accession>
    <name>C7PW42_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4426"/>
    <dbReference type="EnsemblBacteria" id="ACU73290">
        <property type="protein sequence ID" value="ACU73290"/>
        <property type="gene ID" value="Caci_4426"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4426"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107220_1_2_11"/>
    <dbReference type="OMA" id="HYENDYC"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="15569" checksum="50B6E285EEE16B6F" modified="2009-10-13" version="1">MSEASREIVLNAWKTFASHDAVQIEPVFTEDAEWLAPPGNATALALDCPSHMIGRTAIAGFLANDFGRLFVADVEVTFRGIHATDDLVVIEETMRSTLPGGGHYENDYCLVFELRDGLIHRVREYMDTSRAHRMVFGAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWB5</accession>
    <name>C7PWB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793092.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4500"/>
    <dbReference type="EnsemblBacteria" id="ACU73363">
        <property type="protein sequence ID" value="ACU73363"/>
        <property type="gene ID" value="Caci_4500"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4500"/>
    <dbReference type="eggNOG" id="ENOG502ZBG0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058182_0_0_11"/>
    <dbReference type="OrthoDB" id="1937748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="37586" checksum="6083F1EFEAB6D98B" modified="2009-10-13" version="1">MTSTGAADAADHATNPATNPATNPDADAGSSSDAGVPADLAPSTEPDPDPDPEPNPDPDPASEIEAALAEAEQWFVRHGVPHFVEDRYAVTGLPAFLRPFAAGIRLARLGAMLGYWTLRRVLAEVREVGHLAVRALPLLALFGMVIFFSGDFWRIAAALSTGWLWVTAAFFVVLIQAFLVARLPEETGTLPRACTPDRIRASCAATPLAAFAEGEPDLATDPALGLGQRRNMFMYLLLTQTIQISLLSWMVFFFYVVFGAIAIRPEVLKDWFGQVPPDAQLWGMTLPVNSQTLHVAVLLAGISALYFAITALTDAVYRREFFDRTLAELDKAIHMRCAYLTVRGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWQ0</accession>
    <name>C7PWQ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795059.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6480"/>
    <dbReference type="EnsemblBacteria" id="ACU75330">
        <property type="protein sequence ID" value="ACU75330"/>
        <property type="gene ID" value="Caci_6480"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6480"/>
    <dbReference type="eggNOG" id="ENOG5033WPJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073065_0_0_11"/>
    <dbReference type="OrthoDB" id="984550at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045727">
        <property type="entry name" value="DUF6081"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19559">
        <property type="entry name" value="DUF6081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="29647" checksum="C6AA384B32480360" modified="2009-10-13" version="1">MAFSSAAEAADPIAASWRVVFRDDFRAGSALAPGSWRLRPAGAGLPDGDGVVSTGSAGLVVVPAHTDPDTGEPAFSPTDGPLGEMDHLRWAAFADVPPPDAAGRTEVSATISAQGFGLDRHPYGDSVPDPHRELKCGAAVLICVDRPTGIVLDFIVTDRCVFAVYERLAFPGTDWAGFSYAVPVLDREPGDHHDLAILYDAPAGTARWSVGGEQVLAVDELGLRLPGEQAARFAKRDNGLRAQIAVPAQFSFGLGVFTDQVWGQGVRLAVQQFTIRQATTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX79</accession>
    <name>C7PX79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0478</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784725.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0478"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69430">
        <property type="protein sequence ID" value="ACU69430"/>
        <property type="gene ID" value="Caci_0478"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0478"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_24_2_11"/>
    <dbReference type="OMA" id="FLNWYNV"/>
    <dbReference type="OrthoDB" id="1445278at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="207"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="37043" checksum="152B5F6D8E01BC2D" modified="2009-10-13" version="1">MKVSIIMATYDKRDYLEYTLASLAGQTHSDFELVLCDDGTEGGVADLIAPYRDRFAIVPLVQANAGRAAARNTALARASGDLVVFSDDDRILPPEFLAAHVSAHSAGGEEDLAVIGWKKRGVTVWIPRMLPVDESDLTTLARRVGGVEPLASPLRTIEPGDVAVSYPVAVSRMELGDEPDNYHAIVDKYGDELADFRFGWVLATTANLSVPRALLDKIGGFDDGFQGWGVEDTDLSYRLWQAGTRFRIERAAVNHHQVHPIGTGNALLDNRRRRAALMANVEFFCRKHQTLEAYLFKRRWEHAMTLDEANRLLAEVEAGVGHSVREELLRLYAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXK7</accession>
    <name>C7PXK7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2542"/>
    <dbReference type="EnsemblBacteria" id="ACU71460">
        <property type="protein sequence ID" value="ACU71460"/>
        <property type="gene ID" value="Caci_2542"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2542"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_769123_0_0_11"/>
    <dbReference type="OMA" id="DFTDNQW"/>
    <dbReference type="OrthoDB" id="1012759at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="380" mass="40291" checksum="10C4A8CC7871584E" modified="2009-10-13" version="1">MTGTAADPAASPIANPVTFGVVGSGWRSEFFVRLAALLPEQLTLVGAAVRRAQSVEEVGRRWNVPVYLSAAELVAKQKPDFVIVSVPWPVTPEVVAELAGQGVPVLAETPPAPDADGLRELWAAVGDTGLVQVAEQYLMLPGHAARLELVRRGVIGQPTSVQVSSTHGYHAVSMIRGLLGAGGSGSAFGFGPVRVSASQFTAPLLDPLTRAGWTGDDTPKDAATTLATLDFGNGASGLYDFTDNQWHNRLRLRRILVRGSLGEIADDTVIRWGGPATVLRSELVRSQLGHDLNLDGHDTEHLSFDGGVVYRNPFLGLRLMDEEIAIATLLTATAAWVRNAGPEPYPLAEACQDHLISLAIDEAAVLGEPVVTALEPWGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP7</accession>
    <name>C7PXP7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2582</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2582"/>
    <dbReference type="EnsemblBacteria" id="ACU71500">
        <property type="protein sequence ID" value="ACU71500"/>
        <property type="gene ID" value="Caci_2582"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2582"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="44424" checksum="12507A388B5B1129" modified="2009-10-13" version="1">MLADMSDIDAETLAPSYPMPRTCPLDPAADLGRLRAAQPVSRVRLDFDGSVVWLITRYEDAKTVLADPRFSSDFATPGFPARLTAQPPGPGTFIRMDPPDHTRLRRALIPELVRARVKELEPVIAGHVEQLTDRLLAGPTPTDLVEEFALPLPSQVITDLLGVPYQDREFFHQTTKVMGDVHVDGQTRMKVRNDLRAYLDELIAGKEADLPDDLLGRMSRRRAEAGLSREEVVGIATLLMVAGYETVANQIAVGTVALLAEPGRWAALAADPAKLPAAVEELVRHQTVTDYGARRAATEDVEVAGQLIRKGEGVLVSLAAANRDESVFPDPDRLDLDREFVDHLSFGFGLHQCVGQVLARAQLMAAWSTLLRRIPGLRLAVPVDDVPFRNDMFVYGVHALPVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXS8</accession>
    <name>C7PXS8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-hydroxyglutarate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786824.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2614"/>
    <dbReference type="EnsemblBacteria" id="ACU71531">
        <property type="protein sequence ID" value="ACU71531"/>
        <property type="gene ID" value="Caci_2614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2614"/>
    <dbReference type="eggNOG" id="COG0579">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024775_0_1_11"/>
    <dbReference type="OMA" id="NCAFSKG"/>
    <dbReference type="OrthoDB" id="1371190at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="42323" checksum="55A27B57E3BD515F" modified="2009-10-13" version="1">MRNVVIVGGGIVGLAVAWELTGRGLGVTVLEKEAGWAAHQTGHNSNVVHAGLYYKPGSFKARMSVAGNRSIVEFAREHGVPVEVCGKLVVATGDEEIPALDTLAERAVANGVPAKRITPAEAREYEPEVACVAALRVESTGIIDYPGVCAALVRLLGEAGADLRLNSAALGIRAGRNGGVEVATASGVVRADALVNCAGLHSDRVARLAGLTPSAQIVPFRGEYYELRPERRHLVKGLIYPVPDPTLPFLGVHLTRMLDGSVHAGPNAVLALRREGYRWTDFSAKDVAEVAAFPGTWRLARRYAIPTGLDEVRRSFSKKRFAASLARLVPAVTEDDIVRHGSGVRAQAMRRDGSLVDDFLIETARDQVHVLNAPSPAATSALEIARHIADRVTQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYB1</accession>
    <name>C7PYB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795130.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6554"/>
    <dbReference type="EnsemblBacteria" id="ACU75401">
        <property type="protein sequence ID" value="ACU75401"/>
        <property type="gene ID" value="Caci_6554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6554"/>
    <dbReference type="HOGENOM" id="CLU_715139_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="39008" checksum="9A37AFA8F98DD004" modified="2009-10-13" version="1">MSENEFEEEIKGLLSGLAEAEVGDSAPVGRMRRDFRAAAARRRRVVTTTTALAVTSGVTLGVAFGAGGNSGSTGNAGAIGPADSAGVAAPRAVTTTAPTPKPTPTPTPKPAAEPSPQIPAGPLVDANCVTANGKTFIGDVNRVPMSPRGSLAGDNAFVGTVLARAEALVPANAAKVEMADDDGHSRVAVVYLNPKAAKSNGPCDKGMEAVVFHGPSGASVEDLLVQAGGVFYGPDYGFNWAERNDDGSESIAVVYPEADKTVSFDGSLLSTDSTAKVSHETNNGELLVTLPAGAALPVFIDVPSLGMVPGGTAGSPLMFVAAKGDAAAYAAAIGGDITKVGPLPKGMTGTGFSYPKTEGNEWSSHKDPRTLTGPGTDPGLWMSFIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYH3</accession>
    <name>C7PYH3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6617</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6617"/>
    <dbReference type="EnsemblBacteria" id="ACU75463">
        <property type="protein sequence ID" value="ACU75463"/>
        <property type="gene ID" value="Caci_6617"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6617"/>
    <dbReference type="eggNOG" id="ENOG5033XVA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027956_2_0_11"/>
    <dbReference type="OMA" id="HYSRASW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021224">
        <property type="entry name" value="DUF2690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10901">
        <property type="entry name" value="DUF2690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="33513" checksum="9CBAA3163755B6D0" modified="2009-10-13" version="1">MTAPQPDIPGEVTRLAAELRRLREQTGLSFTALSEQTPYSKSAWQRYLTAKVLAPWPAVQELGRLAGEQEPRLRALWELAESATRRRAAVMAGPGGTEPPETTKATKATEPTETTNSPNSARPAESATPETRTETKPETGPAFPRERRARVAVAMILVATVVAAVLGVAGVRLLHGTGVTGGTTSKVLNGRFSVICTSGSCDPTCQGAACTGQDPQMTLCGVQGLPLHREQTASGVGVEILYNPRCRAAWASFWNTQIGDTLTVAAPGQPTESVRVSDPRYTSGFTYTPMVFVAGSGTALKACITSPSGVPDCSAATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYR5</accession>
    <name>C7PYR5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="12" type="ordered locus">Caci_8568</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8568"/>
    <dbReference type="EnsemblBacteria" id="ACU77387">
        <property type="protein sequence ID" value="ACU77387"/>
        <property type="gene ID" value="Caci_8568"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8568"/>
    <dbReference type="eggNOG" id="COG0035">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067096_2_3_11"/>
    <dbReference type="OMA" id="TYATRMP"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="133"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="205"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU77387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="22838" checksum="F47E24796AA6E5D8" modified="2009-10-13" version="1">MPTVSIHVVDHPLVAHKLTVLRDARTDTPTFRSLADELVTLLAYEATRNAQVEPTTVRTPVAEAAGVTFSGPRHLVVPVLRAGLGMLDGMVRLLPTAEVGFLGMVRNEDTLQASTYATRLPEHLVGRQCYLLDPMLATGGTLIAAIRLLAERGAASVTAVCLLAAPEGVAAVQKALADLDLPVAIVTAAIDERLNENGYIVPGLGDAGDRLYGTVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYU0</accession>
    <name>C7PYU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797137.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8593"/>
    <dbReference type="EnsemblBacteria" id="ACU77412">
        <property type="protein sequence ID" value="ACU77412"/>
        <property type="gene ID" value="Caci_8593"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8593"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_777768_0_0_11"/>
    <dbReference type="OMA" id="WFGWATF"/>
    <dbReference type="OrthoDB" id="229486at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="168"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="356" mass="37018" checksum="D2544A78A064EC53" modified="2009-10-13" version="1" precursor="true">MTNRFLRSGAAGAALLTSVLGLPYVLLAYIGSPLPAKAPSPARMAWWLKSGQFDDRAAVVVLAYVLWACWAIFIVQVAAQLPGAVRAAVRVRHGGQPQTGRTRSLVGGGVVQVLLTALLVTLFVPRSAVAATSVGLVGASGSMDARPAAVGLPVPGAESSKAGEQTVRVHVVERGDNLWDIAATYLGDPNRWPEIYEKNVGIPQPDGLVLTNPDVVQPGWTLTMPVAADAAKQGPAYVPSQVPQASDVVPNNDEHSSTAPTTSPNEPNRSAEARQSAAFAEAGRVQAAPRDRVAISLGADGYVGIGLAAGIAAALTAGRLRRRARARAQFPIPLDGVPADGGVGRTCSRSWNVRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ63</accession>
    <name>C7PZ63_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATPase AAA-2 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_0684</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0684"/>
    <dbReference type="EnsemblBacteria" id="ACU69619">
        <property type="protein sequence ID" value="ACU69619"/>
        <property type="gene ID" value="Caci_0684"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0684"/>
    <dbReference type="eggNOG" id="COG0542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_1_11"/>
    <dbReference type="OMA" id="KRYITDH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="39"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="467"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="841" mass="92123" checksum="08AF1912F8592E99" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE0</accession>
    <name>C7PZE0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786890.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2681"/>
    <dbReference type="EnsemblBacteria" id="ACU71597">
        <property type="protein sequence ID" value="ACU71597"/>
        <property type="gene ID" value="Caci_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2681"/>
    <dbReference type="eggNOG" id="COG4289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028269_0_0_11"/>
    <dbReference type="OMA" id="ETRPWIW"/>
    <dbReference type="OrthoDB" id="205789at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016624">
        <property type="entry name" value="UCP014753"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35339">
        <property type="entry name" value="PTHR35339"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10022">
        <property type="entry name" value="DUF2264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="678" mass="73302" checksum="0FC87D36D4E243E0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q075</accession>
    <name>C7Q075_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6722"/>
    <dbReference type="EnsemblBacteria" id="ACU75568">
        <property type="protein sequence ID" value="ACU75568"/>
        <property type="gene ID" value="Caci_6722"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6722"/>
    <dbReference type="eggNOG" id="COG4209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_1_11"/>
    <dbReference type="OMA" id="DKWLYLL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="118"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="38769" checksum="0B229830C8BDE7D6" modified="2009-10-13" version="1">MTEIRAADRPVPRSVPEKAAFGGRPRIRARRSRSSRRAGAAARRPSLTLWQRIKRDKVMLALMLPGFLYFAVFSYAPLFGYLAAFEDYQPYTGFVHSTWVGLQNFTDLFADQAFWSALTNTFVISFIQLVLFFPAPIGLALLLNSVASARIRKFVQSVVYLPHFIGWVVIVSIFQEVLGPTGAMQHMMTSVGLPRFDFMSNPGFFPWLVAIQAIWKDCGWGTIIFLAALLSIDQGLYEAAAVDGAGRWRRFRSVTMPGLMPVVILLLILRLGTILSVGFEQILLQRDTVGAKAGEVLDTYVYYHGVATQQWGTAAAAGLIKAAVGLVLVLGANKVAHRFGQEGIYSRGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S8</accession>
    <name>C7Q0S8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Succinate dehydrogenase hydrophobic membrane anchor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0771</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785001.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0771"/>
    <dbReference type="EnsemblBacteria" id="ACU69706">
        <property type="protein sequence ID" value="ACU69706"/>
        <property type="gene ID" value="Caci_0771"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0771"/>
    <dbReference type="eggNOG" id="COG2142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145876_0_0_11"/>
    <dbReference type="OMA" id="WLFMRLS"/>
    <dbReference type="OrthoDB" id="1992496at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16951" checksum="3A038BCF0DEE77EF" modified="2009-10-13" version="1">MAQSTHVSLEAPRTGNPGRSQRYRSRKGPGKVTRGNFELYSWLFMRASGVLLVFLVLGHLFIMMVTDGGVEKIGFAFVAGRWASPWWQFWDLLQLWLAMIHGSNGMRTVINDYADKDRTRAILKGLLYTAAVLTIALGTLVIFTFDPNIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0W7</accession>
    <name>C7Q0W7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785040.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0810"/>
    <dbReference type="MEROPS" id="S54.029"/>
    <dbReference type="EnsemblBacteria" id="ACU69745">
        <property type="protein sequence ID" value="ACU69745"/>
        <property type="gene ID" value="Caci_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0810"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067823_2_0_11"/>
    <dbReference type="OMA" id="NNPEHAM"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="60"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27562" checksum="D203BCF618E765C0" modified="2009-10-13" version="1">MNGPGSWDGRSAEEVLYEARKALYVMVGFIAVIWALQVVNWATDYRLSTHFGIVPRNVGHLGDIISSPFLHYSWQHIESNSGPLFVFGFLAAYRGVRKFLMVTLIITFSSGLMVWFAQGNSNTVGASGLVYGYFAYVVVKGLFDRHLVDVLIGCVMALSYAYLLTAALPGVPHVSWLGHLGGAIGGVLAGWLLRERGASSAAEPVSGPGREPLGDSGLSNTKILPAPAKDGGRKTAKGGSLPGNPRSDLLKELDDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q156</accession>
    <name>C7Q156_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2822"/>
    <dbReference type="EnsemblBacteria" id="ACU71731">
        <property type="protein sequence ID" value="ACU71731"/>
        <property type="gene ID" value="Caci_2822"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2822"/>
    <dbReference type="HOGENOM" id="CLU_2394391_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="93" mass="10458" checksum="0379E167DFB04BC7" modified="2009-10-13" version="1">MRLACRVSWRTVETMTRPPCLPDVMASEIRHTLVPASSITAGDTVRHLDMWFEVRSVMRLNGDVCIALKTASMEQRLVLQVPADAQVMTWTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q176</accession>
    <name>C7Q176_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787044.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2842"/>
    <dbReference type="EnsemblBacteria" id="ACU71751">
        <property type="protein sequence ID" value="ACU71751"/>
        <property type="gene ID" value="Caci_2842"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2842"/>
    <dbReference type="eggNOG" id="ENOG5033UHX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1101336_0_0_11"/>
    <dbReference type="OMA" id="LQVMAFT"/>
    <dbReference type="OrthoDB" id="1900520at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="26001" checksum="9754F03E2B4BBB05" modified="2009-10-13" version="1">MSKRSGLGQQLFVGGYDLSGDIGSLSKISGSVAVLDVTGINKFAFERIGGLRDGAMDFMAFFNTATGQAHPVLSALPRGDVGVMMLISTTLGDPAACLVAKQLNYDGTRATSGAFTFNVGTQANGFGIEWGKTLTAGKRTDTAATNGTSVDGGATNAPSAFGLQAYLQVMAFTGTDVTVKIQDSADNATFADLSGAAFTQITSTTPQTQRIAISNSANVRRYLRASTVTTGGFTSLAFAVAYVRNPIAGQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D6</accession>
    <name>C7Q1D6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73665">
        <property type="protein sequence ID" value="ACU73665"/>
        <property type="gene ID" value="Caci_4804"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4804"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069623_3_0_11"/>
    <dbReference type="OMA" id="WIDLMAS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="138"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="27439" checksum="975BC80A3D27837D" modified="2009-10-13" version="1">MKMTEYVPGTPCWVDLGTTDLEGAKAFYGGLFGWSAQVAEDPAAGGYTTFLLNGEQVAGAMTTMSPEQPVAWSTYVAVSDADAAMTRAEGAGAKAIVPPMDVMDIGRMAMFADPTGAALGLWQPKTMKGAGLVNEPGALAWDELNTRDAEAAKAFYAAVFGWDAKTTPMGEGMEYTELKLNTRTVAGLMVMDDEHFPKETPPHWAVYFGVADCEASVAKVGELGGTIVVPTTPIPMGRFAVCQDPQGGFFSMFESSGASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1P9</accession>
    <name>C7Q1P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase U61 LD-carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795329.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6755"/>
    <dbReference type="MEROPS" id="S66.001"/>
    <dbReference type="EnsemblBacteria" id="ACU75600">
        <property type="protein sequence ID" value="ACU75600"/>
        <property type="gene ID" value="Caci_6755"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6755"/>
    <dbReference type="eggNOG" id="COG1619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034346_3_1_11"/>
    <dbReference type="OMA" id="GFIFGQC"/>
    <dbReference type="OrthoDB" id="952832at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="19"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="186"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33820" checksum="5FA4C234F1D21CC5" modified="2009-10-13" version="1">MTGLRTLLRPPALKPGDSVAVLCASSPVPGQPQLESGLRAMESVGLKPDVFATTRADRLYDYLAGTDAERAADLTRALTDPKYAAVFLACGGYGMQRTLELMDWSRINAAAPKVVVGYSDVTALLEAIAVKLGWVSLFGPMVACSGFWQGPDEYDFKELMKLLYAPSAVSRLTFPGSRALVSGVAEGLTLGGTATLIAANFGTDTSFPVRDAILFLEDVDELPFRLDRIFTQFRRAKDYLDGVRGIILGTFSECGDPEQLDQLLAERFGDLGVPVLAGVNIGHNCQMQTYPVGVRARLDADAGTLTFLDQVLAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Z6</accession>
    <name>C7Q1Z6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795425.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6857"/>
    <dbReference type="EnsemblBacteria" id="ACU75697">
        <property type="protein sequence ID" value="ACU75697"/>
        <property type="gene ID" value="Caci_6857"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6857"/>
    <dbReference type="HOGENOM" id="CLU_1515249_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19464" checksum="BF3F81DD7573918B" modified="2009-10-13" version="1">MLLAALTEELLPVAWQRFDQDSFGRRSTEFRRLPHRAVLTVTANAVNGTNVHLFSGEIDVPWRVTADDPDPVVIAAAANAALDESRSLGAPLTDLLVAASWHREADEFGYGAAERRWVSPDGQRDAIQFSDDCERLNDWLISLPPTRLMPRRTQYVTSPYTPAAVLAAVALGDALLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2X8</accession>
    <name>C7Q2X8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787163.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2961"/>
    <dbReference type="EnsemblBacteria" id="ACU71870">
        <property type="protein sequence ID" value="ACU71870"/>
        <property type="gene ID" value="Caci_2961"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2961"/>
    <dbReference type="HOGENOM" id="CLU_1802605_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="16548" checksum="D888A8D7C46480C0" modified="2009-10-13" version="1">MNDRPTPERLAEIRSIHEVNWAHPTLGLVTSMERVMCNDLLNEVDALIRERDERPTVVVQFDGPLNEAGYQKLAERWREIVEQDKGKPLQILAPDRTDYGRFEMYYDSDIMACLDCYAFTAPTNVNLADYVAWADGHRCEVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q350</accession>
    <name>C7Q350_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4926"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73786">
        <property type="protein sequence ID" value="ACU73786"/>
        <property type="gene ID" value="Caci_4926"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4926"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023231_2_0_11"/>
    <dbReference type="OMA" id="PWLANNG"/>
    <dbReference type="OrthoDB" id="956236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982846" evidence="1">
        <location>
            <begin position="23"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="520"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="713"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="748" mass="77680" checksum="1EFB8062153BF534" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q373</accession>
    <name>C7Q373_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793538.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4949"/>
    <dbReference type="EnsemblBacteria" id="ACU73809">
        <property type="protein sequence ID" value="ACU73809"/>
        <property type="gene ID" value="Caci_4949"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4949"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_11"/>
    <dbReference type="OMA" id="KLDKAGW"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="26230" checksum="C12ED4A60D20FF5F" modified="2009-10-13" version="1">MTSNRFDLTGRLAVVTGARRGIGRAMARALAEAGADIIGVSAHLEGAGSDVEKDVTAAGRAFEAVQADFSDPAAVAALAADLAGRERPVDILVNNAGTIARTPAARHSDADWALVLQVNLSAQFVLTRAVGERMVERGRGKIVFTASLLSFQGGITVPGYTAAKHGIAGLTKALANEWAPHGVNVNAIAPGYIATDNTQALRDDAERSAAILSRIPAGRWGDADDLAGATVFLASDAAAYVHGAILPVDGGWLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3H5</accession>
    <name>C7Q3H5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6903</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795468.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6903"/>
    <dbReference type="EnsemblBacteria" id="ACU75740">
        <property type="protein sequence ID" value="ACU75740"/>
        <property type="gene ID" value="Caci_6903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6903"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="VMSFQEY"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="100"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="35539" checksum="811B8ABB5E834413" modified="2009-10-13" version="1">MTIVNRVPQAVNEFNGGSYAGAGRPPRSRRRALRSALTPWYFLAPVLAYLLLFFGYPIVKNVEMGFQDYSTSTFYTGVAPWVGFANYSQVFHSGIFTTALTNTAVFTIGSITGQFVLGLALAVFFKRKFPLNGVLRSLFLLPWLIPLIASSAVWKWILDQDSGVLNQTLLNLHLIHTPIPWLSSPSVALLAVMIVNIWLGIPFNLTILYSGLQAIPAEQYEAGALDGATGWKAFWYITLPNLRPVIGIVLMLGVVYTLKVLDIILGLTGGGPANATQTLATESYQQSFTQFQFGQGAALSNILIVISLVFTMFYLRSQRAQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q437</accession>
    <name>C7Q437_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="7" type="ordered locus">Caci_0965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785191.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0965"/>
    <dbReference type="EnsemblBacteria" id="ACU69897">
        <property type="protein sequence ID" value="ACU69897"/>
        <property type="gene ID" value="Caci_0965"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0965"/>
    <dbReference type="eggNOG" id="COG0203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074407_0_0_11"/>
    <dbReference type="OMA" id="YAVTELF"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="19185" checksum="3E7A36EBD9E80360" modified="2009-10-13" version="1">MPQPKKGARLGGSPAHQKLILANLAKSLFEHDKITTTEAKARLLRPYAERLITKAKKGDLHNRRQVLAVLRDKDIVFRLFDEIAPNYENRPGGYTRIIKAGNRKGDNAPMAVIELVEALTVQQTAVREAEAATKRASKKTAAPAPAKAEVEAEPEAVEEAPAAEAETTEAEAAEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J0</accession>
    <name>C7Q4J0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787252.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3050"/>
    <dbReference type="EnsemblBacteria" id="ACU71959">
        <property type="protein sequence ID" value="ACU71959"/>
        <property type="gene ID" value="Caci_3050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3050"/>
    <dbReference type="HOGENOM" id="CLU_2895732_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="62" mass="6818" checksum="83424B923611C24F" modified="2009-10-13" version="1">MSATTRPRGICPVCGKNIRVKQDGRMFFHGYSVAIRNSGDRYANAGFCRGFNKPPVEAVSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q565</accession>
    <name>C7Q565_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795562.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7004"/>
    <dbReference type="EnsemblBacteria" id="ACU75834">
        <property type="protein sequence ID" value="ACU75834"/>
        <property type="gene ID" value="Caci_7004"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7004"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_8_11"/>
    <dbReference type="OMA" id="WIEHHQF"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="915"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2683"/>
            <end position="2758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2642"/>
            <end position="2664"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="953"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2846" mass="295745" checksum="F41B8DEB592A46EF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T9</accession>
    <name>C7Q5T9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Activator of Hsp90 ATPase 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785330.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1110"/>
    <dbReference type="EnsemblBacteria" id="ACU70036">
        <property type="protein sequence ID" value="ACU70036"/>
        <property type="gene ID" value="Caci_1110"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1110"/>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084739_0_0_11"/>
    <dbReference type="OMA" id="WFNQLEH"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27759" checksum="CD7CA1E3802BC35E" modified="2009-10-13" version="1">MTHPFEIELETTLPATPEQVWDAIATGPGVDSWFMGRNEIEAREGGTAAMDTGGYREEAVVTAYDPGKRLATRTSPDADGRFMAFEYLLEGREGGSTVLRVVHSGMLGDDWENEYDALRRGWPFHLHTLHEYLAHFPGRTAFPVFGMAPTGDGPSQDVQALLAGALSLTAPVTTGSRVDGGPSAAPVVGGEVVWADSERFGVRSADALYTFHHGSGVALMFHHLFAPAESEAASEEAWQHWLTATVQNTDQNTNEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5U0</accession>
    <name>C7Q5U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785331.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1111"/>
    <dbReference type="EnsemblBacteria" id="ACU70037">
        <property type="protein sequence ID" value="ACU70037"/>
        <property type="gene ID" value="Caci_1111"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1111"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097480_0_0_11"/>
    <dbReference type="OMA" id="DSEIRFA"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23702" checksum="3E21997195A6C2F8" modified="2009-10-13" version="1">MLDVAVIAEPAAAEASLDPIRSRILAALAEPGSAAMLAGRLGLPRQKINYHLKELERHSLVELVEERRKGNVTERIYGATAAAYVISPSTMGAVSPDPDRSPDRLSARWLLALGSRLIQEVGTLLTGSARAGKPVATYAMDAQVRFASAADRAAFAEELTQAVTALVSRYHDEHAPHGRDHRLVVGLHPIPTAPPTPTTPTGPQPAAETAPLPEPEAGQEDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5V1</accession>
    <name>C7Q5V1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Triacylglycerol lipase</fullName>
            <ecNumber evidence="3">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785342.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1122"/>
    <dbReference type="ESTHER" id="catad-c7q5v1">
        <property type="family name" value="Fungal-Bact_LIP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70048">
        <property type="protein sequence ID" value="ACU70048"/>
        <property type="gene ID" value="Caci_1122"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1122"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_5_1_11"/>
    <dbReference type="OMA" id="RQYCATG"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="entry name" value="PTHR34853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981430" evidence="2">
        <location>
            <begin position="34"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="45377" checksum="B2E9C1547E8D7575" modified="2009-10-13" version="1" precursor="true">MRRRPVRRAAATAAVVALAAAGISTATATTSSAAASDSFYTYSGSAPLASYAPGTVLNTRTLQYHVVGIPTPVTAIQILFRTTDAQGRATAGVTSVIRSISGNSGKAVSYQSFYDSLNPADSPSRAIAGDLTLGGVIPNAEALFVTPLVLQGYNVVIPDTEGQSADFAAGPEYGTTTLDSIRAAESSAAGTGMTSATKFGLEGYSGGAIATGWAAALAPSYAPEVNQDLVGFAEGGLLVDPAHNLKYVAGSLVWSGVIPMAIIGVARSYSIDFSKYLNSYGMKVYNQLQQGSIVNALGEYPGLTWQKMAKPQYANPDSVPEFVAAVNKINLGSVGTPTVPGYIAQGGGGILEGTLSNPPGIGTGDGVMVAGDVRALARQYCATGDGSIKYDQFDLLSHTGTAVPWAPLALLWLNDRFAGNAAPSDCGSIAAGNSLTPEQVVPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q619</accession>
    <name>C7Q619_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ordered locus">Caci_1191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785410.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1191"/>
    <dbReference type="EnsemblBacteria" id="ACU70116">
        <property type="protein sequence ID" value="ACU70116"/>
        <property type="gene ID" value="Caci_1191"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1191"/>
    <dbReference type="eggNOG" id="COG1490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076901_1_2_11"/>
    <dbReference type="OMA" id="GVFQAHM"/>
    <dbReference type="OrthoDB" id="1862614at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="15464" checksum="2FA9650C4E9BA2FB" modified="2009-10-13" version="1">MRAVVQRVSEASVRVAGEVVGAIEGPGLAVLVGVTHDDTPAKAAQLARKLWSLRLFEGEVGEPGTEQSCSDFGGPLLVISQFTLYGDARKGRRPTWSAAAPGPVAEPLVEVVVAELRGLGAKVETGRFGADMKVALVNDGPFTVVLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q648</accession>
    <name>C7Q648_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787347.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3145"/>
    <dbReference type="EnsemblBacteria" id="ACU72054">
        <property type="protein sequence ID" value="ACU72054"/>
        <property type="gene ID" value="Caci_3145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3145"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003134_1_0_11"/>
    <dbReference type="OMA" id="YASQRDY"/>
    <dbReference type="OrthoDB" id="7548at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023836">
        <property type="entry name" value="EccCa-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023837">
        <property type="entry name" value="EccCb-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03924">
        <property type="entry name" value="T7SS_EccC_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03925">
        <property type="entry name" value="T7SS_EccC_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="461"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="820"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="1114"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="484"/>
            <end position="491"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="839"/>
            <end position="846"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1333" mass="142299" checksum="6B483BAD91195315" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q697</accession>
    <name>C7Q697_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3196</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3196"/>
    <dbReference type="EnsemblBacteria" id="ACU72103">
        <property type="protein sequence ID" value="ACU72103"/>
        <property type="gene ID" value="Caci_3196"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3196"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_11"/>
    <dbReference type="OMA" id="THEINPI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980628" evidence="4">
        <location>
            <begin position="33"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="52"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="36021" checksum="18C56BE894291851" modified="2009-10-13" version="1" precursor="true">MAVDTDSEAAVGAVAAVAAGAAVAAGAHPAGAATLDSTDRRCNAGNDPVAVVELIGASAAVAGRTLWGGVNLTVECGEFVAVLGPNGVGKSTLIKVLLGVLPAAAGEVRVLGRRPGAAGAQIGYLPQRRSFDASLRIRGVDVVRLGLDGDRWGIPLPGTRRFNARRRAEQDRVEEVIDLVGASAYAHRAIGECSGGEQQRLLIAQALVRRPRLLVLDEPLDSLDLPNQASVAALIGRISRSEDVAVVMVAHDVNPILPYLDRVVYLADGGAASGTPEEVITTETLSNLFGTPVEVLRASDGRLVVVGGPEAPVLHSDRHTAAAVAAPPAPIAAQRLAGRRPNGSEADRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6E2</accession>
    <name>C7Q6E2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3241"/>
    <dbReference type="EnsemblBacteria" id="ACU72148">
        <property type="protein sequence ID" value="ACU72148"/>
        <property type="gene ID" value="Caci_3241"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3241"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032284_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="73"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="501" mass="53853" checksum="5BBE36D8CAEA2D70" modified="2009-10-13" version="1">MTVSATSQGTVSQDAVSQGTAVSAVSAVFAETPDGCPSPGSPIAATRTLEVPFSGDAAGSGGLNWGQQHIFGAIRNLGSSMNMCAVRELPPGAAVEDYAEELSFYLNRFQAMRTLLRFEAEHPPIQIVHASGTVPLQIVDLYDDADATVAISELVAEHEQRSFDDEREFPIRMVLIRQAGVLTHLLTVLNHFATDGAGAFAMYEDFLHRDPVTGLARGPAPIHPLDLTAQQATPAGRRQSDASLRYWEKQLAALPRRRPTAAVPETGSRYRRATLRSVPLLLGATRIAHRLDCDVSAVLLGLFATALARLTGERPTAAQMLVSNRFRPGMADIVGNVSQSGLFVVDVTPGTLDDVIESAQRAVTRTYKYAYFDLEQWKALLAAVERDRGEDLALCYYNDRPSQRSGTAPGAQPTPEAVAEAAPGSIIWTDLPFFNEHLMITIDNIPDDDTAITVLVSADTWHVPRKDMETLARTMESLAVAAAYDPATTTGVPAAATAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P9</accession>
    <name>C7Q6P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 76</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5225"/>
    <dbReference type="CAZy" id="GH76">
        <property type="family name" value="Glycoside Hydrolase Family 76"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74084">
        <property type="protein sequence ID" value="ACU74084"/>
        <property type="gene ID" value="Caci_5225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5225"/>
    <dbReference type="eggNOG" id="COG4833">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028686_2_0_11"/>
    <dbReference type="OrthoDB" id="504223at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982843" evidence="1">
        <location>
            <begin position="29"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="614" mass="65456" checksum="B272068F063B0270" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Q7</accession>
    <name>C7Q6Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative chaplin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5233</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5233"/>
    <dbReference type="EnsemblBacteria" id="ACU74092">
        <property type="protein sequence ID" value="ACU74092"/>
        <property type="gene ID" value="Caci_5233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5233"/>
    <dbReference type="eggNOG" id="ENOG50348JU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145456_3_1_11"/>
    <dbReference type="OMA" id="VHSPGVV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="1" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982950" evidence="3">
        <location>
            <begin position="28"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="4">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="7481" checksum="404F18014194E88E" modified="2009-10-13" version="1" precursor="true">MLKTKKIAALVAATGGLVMAGAGMASAEATAGGSSVGSPGIVSGNTIQVPVHVPVNACGLTVSVIGILDQAFGNTCVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q728</accession>
    <name>C7Q728_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795769.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7212"/>
    <dbReference type="EnsemblBacteria" id="ACU76041">
        <property type="protein sequence ID" value="ACU76041"/>
        <property type="gene ID" value="Caci_7212"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7212"/>
    <dbReference type="HOGENOM" id="CLU_1649070_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="16929" checksum="44A9ADB92BBE00B3" modified="2009-10-13" version="1">MPPEQPSRLAAECGQALVAAMPTPDWPALREEAVGMLHDAGPALEGVLVPELDVNARMLLGAAPEHVAVLTDMLAARWRENLVRVLAVNPAADEALRRLVDRIGGTAPAARPAEKTMTNIAKDNSTLFAVMDGNIIQHHHAKPGRGDQASPNQTAADESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q731</accession>
    <name>C7Q731_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795772.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7215"/>
    <dbReference type="EnsemblBacteria" id="ACU76044">
        <property type="protein sequence ID" value="ACU76044"/>
        <property type="gene ID" value="Caci_7215"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7215"/>
    <dbReference type="HOGENOM" id="CLU_1406507_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="19923" checksum="4C185E81713D343E" modified="2009-10-13" version="1">MTDEGNESQGPDTGSRRLCAALASDRPGLLAEACAGGGFARLFLAVLDDGTQAAIAPAGVDEVRLVRDLVEAVTARLPESDGPDSGSPPTLLALNVGIMRVLDDGFAGAGLDRARALANDAAVTAAVSAAVTSAVADHDGADGRKRHGFAVVLSEGLYTDLRDEGYAIEDWHPVRPPGARFRCFGAGTDHEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7M0</accession>
    <name>C7Q7M0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787506.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3306"/>
    <dbReference type="EnsemblBacteria" id="ACU72213">
        <property type="protein sequence ID" value="ACU72213"/>
        <property type="gene ID" value="Caci_3306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3306"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056342_1_1_11"/>
    <dbReference type="OMA" id="DHWLGNH"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="34"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="34546" checksum="9D492BD68EEE33CA" modified="2009-10-13" version="1">MAEYPFPDPVVETSGAVEIASDLVVVPNQDVDLVPNIGVIGGTHSVLVVDTGLGPRNAAQVLAFAAEYAKGRRLYLTTTHFHPEHAFGAQVFAGEATYLVNRAQADDLAQKGAGYLAMFTQLGEPVARELAGTQLPTPDVVFDDGYELDLGGRTVRLRPTGRAHSRGDQVVTVPDAGVLFTGDLAEAGQFAIFPWFPPHDTDVSGLRWIRVMERLAAEPHRVVVPGHGGIGDARLLAEVRDYLSELREQTWRRRDSAMSEETVVEEVRALMVERHPEWRMREWIERGVGCLCAEHEELAAHEARTEQDAEHAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7W4</accession>
    <name>C7Q7W4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-phosphofructokinase</fullName>
            <ecNumber evidence="3">2.7.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fructose 1-phosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5272</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14213"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.56"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.56" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793860.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5272"/>
    <dbReference type="EnsemblBacteria" id="ACU74131">
        <property type="protein sequence ID" value="ACU74131"/>
        <property type="gene ID" value="Caci_5272"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5272"/>
    <dbReference type="eggNOG" id="COG1105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050013_0_0_11"/>
    <dbReference type="OMA" id="GETRSNI"/>
    <dbReference type="OrthoDB" id="1323781at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008662">
        <property type="term" value="F:1-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022463">
        <property type="entry name" value="1-PFruKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03828">
        <property type="entry name" value="pfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="10">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="32674" checksum="0CABDD4A54E6947A" modified="2009-10-13" version="1">MIVTLTLNPSLDRTLELQTLRLGEVLRATSARIDPGGKGVNVTRVLRAFAVDSHAVIPCAGPDGEELVRLLQKAGVPVTEVPVAGWTRSNITLVEADGRATKVNAPGGALTETEVALLAETVVDRCVSQSTENGGASWAVLSGSLPPGVPDDVYASLTSLFAEHGVKVAVDTSGAALLAAVDAGPDLVKPNRQELAAAVGTPLVSLDDVVAAAEKLRSRGVKAVVASLGSDGAVLVDETGAVFGTAEAIDPVSTVGAGDALLAGFLAAGARGADALIEGMAWARAAVGLPGSQMPGPRDVSREGIRVVRDPGGKPAGAVPLADNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Y1</accession>
    <name>C7Q7Y1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793877.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5289"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74148">
        <property type="protein sequence ID" value="ACU74148"/>
        <property type="gene ID" value="Caci_5289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5289"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_14_4_11"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="5">
        <location>
            <begin position="11"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="4">
        <location>
            <begin position="186"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="43121" checksum="F74302B60CE9FCA4" modified="2009-10-13" version="1">MLSTYPPTQCGIATFNAALVRHLNGDGARSSAAVVRVGGDTPSEPEAPEVVAELPGGDPAAAAAAAAALNRFDVALVQHEYGIYDGPDGDEVLDVLNRVRVPIIVVLHTVLARPTAGQHSVLSRICRLCDGIVVLSQTAASRLLEVYGVDSRKVTVIPHGAETDEWQAPGLLPVTGRHDGERYHPLLLTWGLIGPGKGIEWVIDALAEVQDLPTTPRYLVAGETHPKVLQHYGEAYRDSLRERAAARGVAHLVEFDAEYRSRQDLAALAASADAVVLPYESTEQVASGVLIEAVAARRPIIASRFPHAAELLADGAGLLVPHRDARALGVAIRRLLTEPGLAESMERRSAQIAPTLDWAAVTDRYRLLATGLAAHHAPLTEQHGSVAHGRLRAGRRTPVGSTVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q845</accession>
    <name>C7Q845_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5353"/>
    <dbReference type="EnsemblBacteria" id="ACU74212">
        <property type="protein sequence ID" value="ACU74212"/>
        <property type="gene ID" value="Caci_5353"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5353"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_8_1_11"/>
    <dbReference type="OMA" id="TQMPIAK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="15150" checksum="E7FA37ACF827877D" modified="2009-10-13" version="1">MTIDNYSPAQTVEMSGFSLDTLRYYEKIGLIEPVRRAAGGHRRYTDDDLGWLDMLRCLRGTGMPIAQMQTFAELVRDGDGTVTDRLALLEEHDANVEAEMERLIELRRKIQEKIAYYRSYLAEMPVECVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D0</accession>
    <name>C7Q8D0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FolC bifunctional protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7289</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795846.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7289"/>
    <dbReference type="EnsemblBacteria" id="ACU76118">
        <property type="protein sequence ID" value="ACU76118"/>
        <property type="gene ID" value="Caci_7289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7289"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_2_11"/>
    <dbReference type="OMA" id="YFEMGTL"/>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="137"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="309"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="462"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="462"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="515" mass="55645" checksum="D0A23FA54EA3C8D2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8I4</accession>
    <name>C7Q8I4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_7345</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7345"/>
    <dbReference type="EnsemblBacteria" id="ACU76172">
        <property type="protein sequence ID" value="ACU76172"/>
        <property type="gene ID" value="Caci_7345"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7345"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_15_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017205">
        <property type="entry name" value="Sig_transdc_His_kinase_ChrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037434">
        <property type="entry name" value="STHK_ChrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="365"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU76172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="47610" checksum="CC3B3A0CBCDFE2A5" modified="2009-10-13" version="1" precursor="true">MIQPATAVGPEGRAAVPASAVAAAPVAAAPVQDARSDARHDARSAEPHAGAGADTPVSDTIAQDARASFQSWKRIARWWAVGWHFGLAISVVLVAVEHKPVWLYGALAGMSLSYLLLQHRWLLDRGNPRAVYYHLAIVCTLCFAMVWADLSLIYMSSVVLSQFAPLAGFRARGIAILAAAAAVLTFPIAASDGFTSGDLVAWGLTAVGALLFNLFIGLFFGEMLNDHDRRGALIRELEATRAELERAHHEAGVREERERLAREIHDTLAQGFTSLLMLVQAAEATLDTDPATTRERLDLAARTARENLAEARALIGGDPTAGLPLDAALQRAAARIGEELGMATSVDIGGSARTLTATVQVVTLRVAQEALANVRKHARAASVTVWLTYGADRLTLAVEDDGVGMPEAPCGGFGMRSMRERVEQVGGELTITSAPGAGTRVEAEVPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8N1</accession>
    <name>C7Q8N1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkane 1-monooxygenase</fullName>
            <ecNumber evidence="10">1.14.15.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.3" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785590.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1373"/>
    <dbReference type="EnsemblBacteria" id="ACU70296">
        <property type="protein sequence ID" value="ACU70296"/>
        <property type="gene ID" value="Caci_1373"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1373"/>
    <dbReference type="eggNOG" id="COG3239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044462_1_0_11"/>
    <dbReference type="OMA" id="CTYAFIP"/>
    <dbReference type="OrthoDB" id="1202565at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018685">
        <property type="term" value="F:alkane 1-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052869">
        <property type="term" value="F:arachidonic acid omega-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03512">
        <property type="entry name" value="Alkane-hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033885">
        <property type="entry name" value="AlkB/XylM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38674">
        <property type="entry name" value="PTHR38674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="9">
        <location>
            <begin position="126"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="45840" checksum="9E50EF5FEA24550B" modified="2009-10-13" version="1">MSASTLGSTGVRPEAQAWQDGKRYLWPLALVVPILPYVGFGLWHRFDNALAWYLTPFLVYVMVPIGDWLIGEDAGNPPVEREAQLQSAWYYRVLTFLYLPLQFGSLVLGAWAWSQPHVNLASRVGIVVTVGIVTGIAINTAHELGHKREDVERWLSKIALAPSGYGHFYVEHNRGHHVRVATPEDPASARLGESFYRFWPRTVWGSLKSAWVLETKKHRLRKRSPWTLRNDVLNAWLMTLLLFAALTVWLGVGVLPFLLVQMVFGFSLLEIVNYLEHYGLLRQRTASGRYEKVEPVHSWNSDRLSTNVFLYQLQRHSDHHSYPNRRYQVLRSFDEAPQLPGGYATMIVVALFPPLWRRVMDQRVLDHYDGDALKANLTPKLRAKYEAEAAAAASAGATATARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R0</accession>
    <name>C7Q8R0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1402</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1402"/>
    <dbReference type="EnsemblBacteria" id="ACU70325">
        <property type="protein sequence ID" value="ACU70325"/>
        <property type="gene ID" value="Caci_1402"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1402"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1716">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003942_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="117"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="613"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="712"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="637"/>
            <end position="644"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="946" mass="98763" checksum="A5222807D98F5C70" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R8</accession>
    <name>C7Q8R8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma-70 region 4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1410"/>
    <dbReference type="EnsemblBacteria" id="ACU70333">
        <property type="protein sequence ID" value="ACU70333"/>
        <property type="gene ID" value="Caci_1410"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1410"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_577262_0_0_11"/>
    <dbReference type="OMA" id="HAARENM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4" evidence="1">
        <location>
            <begin position="7"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="47514" checksum="BEC11F7289870665" modified="2009-10-13" version="1">MALWKSLSPRDQALHSRRASGETLDSIGQSYGLSRERIRQLISRGEKSWVDQVDALRPGWRASVRQRFAVRPVVAESDFADILPDSVGIVRGTLLRAAGADRARTWAGPIDGIWSMDPSGLAAQLRDLIALAPFTDDDLDTAAANLEFPENTPLRAILTHSRSPLVRGPHDYWLRRNARARDASYLWLLSEGEPRRIEPIVMAVGGNRNAVAEAMRRDSRFRQLRPEGTWALTDWHVPGATEYTNAMDVVVDVLTERGPITRKNLIAEVVRRYPVSAARVVQCLIGVRVGIHRDGRFDLVERGASPYEESEPRRPRNIIIDEAGNIAGVLLTVDREVLRGSGVIVHPWLTWHLGLRRAPMTRRFSVPGGDGDVITVSRHTSGAQFSSMKSFVDDMGLAIGCQFAVLLRLDEETASVRHTCKPDTCTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z4</accession>
    <name>C7Q8Z4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3408</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787607.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3408"/>
    <dbReference type="EnsemblBacteria" id="ACU72314">
        <property type="protein sequence ID" value="ACU72314"/>
        <property type="gene ID" value="Caci_3408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3408"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017999_1_1_11"/>
    <dbReference type="OMA" id="AYGPEAM"/>
    <dbReference type="OrthoDB" id="100199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="575"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="750" mass="80190" checksum="6AD1BA2A81356342" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E1</accession>
    <name>C7Q9E1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5428"/>
    <dbReference type="EnsemblBacteria" id="ACU74287">
        <property type="protein sequence ID" value="ACU74287"/>
        <property type="gene ID" value="Caci_5428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5428"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="TAMIREQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="20662" checksum="DF05ADD9FF655837" modified="2009-10-13" version="1">MADDQAAVRDGLVALLSVTAGVEVVGEAANGAAAVAAAETLRPDVVLMDLRMPGVDGVEATRRIAQSAPDVRVVVLTTHADDASILKALRAGATGYLTKESGRAEIARAIEAAASGQSVLDDGVTAILLAAAVEVPASADLTPREAEVLTLIARGKSNTEIAGELFVSAATVKTHINNLFAKIGVRDRAQAVRYALRRGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J4</accession>
    <name>C7Q9J4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplT</name>
        <name evidence="8" type="ordered locus">Caci_5481</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794069.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5481"/>
    <dbReference type="EnsemblBacteria" id="ACU74340">
        <property type="protein sequence ID" value="ACU74340"/>
        <property type="gene ID" value="Caci_5481"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5481"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_0_11"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14754" checksum="6FA7CF7572733DAC" modified="2009-10-13" version="1">MARVKRAVNAQKKRRVVLEQASGYRGQRSRLYRKAKEQVTHSLVYAYRDRKDRKGDFRRLWIQRINAAVRAEGMTYNRFIQGLHLANVEVDRKMLAELAVNDADAFRALVEVAKKALPSDVNAPKSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA99</accession>
    <name>C7QA99_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HEPN_SAV_6107 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1576"/>
    <dbReference type="EnsemblBacteria" id="ACU70497">
        <property type="protein sequence ID" value="ACU70497"/>
        <property type="gene ID" value="Caci_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1576"/>
    <dbReference type="eggNOG" id="ENOG5032S47">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096112_0_1_11"/>
    <dbReference type="OMA" id="IRSAWEV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040891">
        <property type="entry name" value="HEPN_SAV_6107"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18726">
        <property type="entry name" value="HEPN_SAV_6107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_SAV_6107" evidence="2">
        <location>
            <begin position="54"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="18121" checksum="B1F96598B17F4B2C" modified="2009-10-13" version="1">MPAALTSPDTGPIAGSRAHPPPLPPMGAGGHRRGPASRSARDLFEQAVHELAEAVTTSHPYDRYCGAHMAALHASAAVVTARAVPAAPTRRRPRSVWDLLYREAPELADWAAYFASGATRRAAAQAGLPNAVTDAEAAELAREAEVYLGVVAQLLGLPYQDGLPLSSGEQPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAK8</accession>
    <name>C7QAK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792236.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3603"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH12">
        <property type="family name" value="Glycoside Hydrolase Family 12"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72507">
        <property type="protein sequence ID" value="ACU72507"/>
        <property type="gene ID" value="Caci_3603"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3603"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060511_0_0_11"/>
    <dbReference type="OMA" id="FNGCHYT"/>
    <dbReference type="OrthoDB" id="452479at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="PTHR34002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983074" evidence="4">
        <location>
            <begin position="33"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="269"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="6">
        <location>
            <begin position="356"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="460" mass="46429" checksum="1C945067B8088F54" modified="2009-10-13" version="1" precursor="true">MARLLRARALAAALAIAFTGALSAIALPAAQAATTTCSGTGTIPAGDYTIQANEWNSSAQQCLTYNGATAWTVSTANFNLGGSGAPATYPSIFKGCHWGLCTSNNPFPIQMSKLGSAVSSWDTTQPSSGAYDVAYDIWFNSSPTATGQPDGTEVMIWMNSRGGVQPFGSQTGNTTVAGHNWNVWTGQQSSWKIISYVLNPGATSLSNLDLKAMFQDAVSRGSINPSNYLLDVEAGFEIWQGGQGLGTNSFSVSATAAGSGGGDTTAPSVPANLAVTGTTASSASLSWSPSTDNVGVTGYRVYRNGAQVGTSSGTTFTDTGLSAATHYTYTVAAVDAAGNVSAPSTGATATTTSNGGGGGGSGCTAAYSVTNQWNSGFTANVTVTNSGTAPINGWKVNWTWGGGQQITSLWNGTLSSSGSAVTVTNMGYNGSVAPGANTSFGFQGAYSGTNGTPTLTCTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB51</accession>
    <name>C7QB51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7517</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7517"/>
    <dbReference type="EnsemblBacteria" id="ACU76342">
        <property type="protein sequence ID" value="ACU76342"/>
        <property type="gene ID" value="Caci_7517"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7517"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_6_3_11"/>
    <dbReference type="OMA" id="DTTETIH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="96"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30216" checksum="2007CEA04D2388CE" modified="2009-10-13" version="1">MADIGITSGPAVGSAATTKDGALDGTGGDSAGVKSARRAVELLEAFGSNHSWLSLTDLHHLTGFPRSSLHGLLRTLRDVGWIESDDAGTRFRLGVKALICGTAYLDRDPVMPYATEALEKIRDQIGYTCHFARLNGPDIVYLQTRESRTSAHLVSRVGRTLPAHATALGKVLLAELADDELTGVLPKHLTALTDLTITDREALRSELAFIRERGYSTERGQSSPNLACVAAVVPYRIPGTDAMSCSMPGERVTDAELQRVGALLRDVAEDLSQQLRRAGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBC2</accession>
    <name>C7QBC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7589</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7589"/>
    <dbReference type="EnsemblBacteria" id="ACU76413">
        <property type="protein sequence ID" value="ACU76413"/>
        <property type="gene ID" value="Caci_7589"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7589"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VYAMREK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="155"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="24260" checksum="9BAA7AB1C0BEA0F8" modified="2009-10-13" version="1">MSEAIRVLIADDHTLLRRGLAVVLDTEDDIEVVGEASDGAEALHKAQELAPDVVILDVRMPDTDGLTACAAIKRSVPDTKVIMLTSSDEETDLYEAVKSGASGYLLKSVLPHTIPDALRAVQRGESQVSPSMAAKLMTGFAALARGADAAPAPGPVSSAPKLTDREMEVLKLVATGRNNREIAKELFITENTVKNHVRNILEKLNLHSRMEAVVYAVREKLLEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBG3</accession>
    <name>C7QBG3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785834.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1619"/>
    <dbReference type="EnsemblBacteria" id="ACU70540">
        <property type="protein sequence ID" value="ACU70540"/>
        <property type="gene ID" value="Caci_1619"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1619"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="ADICTSD"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="460"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="478"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="703" mass="72109" checksum="8FF8462B78C45610" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC32</accession>
    <name>C7QC32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3749"/>
    <dbReference type="EnsemblBacteria" id="ACU72651">
        <property type="protein sequence ID" value="ACU72651"/>
        <property type="gene ID" value="Caci_3749"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3749"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="TWWREAA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="172"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="41723" checksum="FF8F1AAA07D82065" modified="2009-10-13" version="1" precursor="true">MARQELLLLSAVAAVALFVVVTLPADIRVLRSHSPQDWLVSAAVYAALVAHRRLPLGTVAVTVAGSVVLMADGMAYPLTLPAVFYVLYSVALETGPGRTLAVGVTVKATLLSASLITHPGLAGFVILLWAALAVTSGGASRSHRGYVVEVEKRVRRAELDREDEANRRVAAERLRIARDLHDAVGHHVALINVQAGALACLLDDEDLGRARESLAHIQRAGEEALEELRLTVGLLRAPGAAEPAEPAEPVPGLDQLEELICSFADTGLRVTREVTGHARPLPEAVELTAYRVIQESLTNTRKHAGCDTAVVRLDYTLGALSLAVEDEGRPAALDTPTARATRNSRDTLGGHGVVGMRERVAALGGRLSAGPRPEGGYRVFAELPLRAARIEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC39</accession>
    <name>C7QC39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5628</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5628"/>
    <dbReference type="EnsemblBacteria" id="ACU74487">
        <property type="protein sequence ID" value="ACU74487"/>
        <property type="gene ID" value="Caci_5628"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5628"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032067_2_0_11"/>
    <dbReference type="OMA" id="IRFKWII"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="54957" checksum="4083C8CF0869D0BE" modified="2009-10-13" version="1">MVVVGAGLSGIGAGYRLQTECPERSYVILEARDAIGGTWDLFRYPGVRSDSDMFTLGYAFRPWREAKSIADGDTIRDYIRSTAEQFRIEEKIRFRTRVVAADWSSEQACWTVTVEQSVADAADADAADAAVERRTLTCDFLYSCTGYYDYASGYTPDFPGVADYQGTVVHPQFWPEDLDYAGKRVVIIGSGATAVTLVPSMVRDAEHVTMLQRSPSWIGAVPGRDKLADQLRAVLPPRVAHRIIRAKNIAFTIGVYQFCRRRPAAARKMLTKLANRFLKDEQMVREHFTPTYNPWEQRLCAAPDADFFRAIRGGKADVVTDHIEAFMPEGIRLVSGKVLEADVVVTATGLRLLALGGIAPSVDGVEVPLAKQFVWRGAMVTGIPNFAVCIGYTNASWTLRGDLTSRLVCKVLNHMKARGYSSVVPVPDGTLRERPLLDLSSGYIQRSIQEFPRSGHRSPWRVRQNYILDAATTMRTDLDRTLRPTRREKAGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC85</accession>
    <name>C7QC85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794262.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5675"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74533">
        <property type="protein sequence ID" value="ACU74533"/>
        <property type="gene ID" value="Caci_5675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5675"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_29_0_11"/>
    <dbReference type="OMA" id="CWRDTGH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="16"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="202"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="388" mass="42822" checksum="9BDEB27D6B1E9E26" modified="2009-10-13" version="1">MRVAILNWRDPWQRSAGGAEAFAHEVARGFVARGDTVDFLTSREPGQPRSELHEGIRWLRRGGRWTVYAGVFGRLIRARLRGPAYDFVIDCQNGIPFFSPLAVSRRRTGVAIVVHHVHDEQFATHFSRPLAALGRWLEGPAARQVYRRHTAVAVSESTITAMRTRLRWTGAIELIHNGVATEGFQRLSLPPALPLASASAPRLVAVGRLVRHKRLEHVLHLADDLAETWPGIEIHIIGRGPDESRIREAASRLHHADRVHIHGHLATQAKNHLLQSAWLHLSASQGEGWGLSVLEAAALGVPTVAYDVDGLRDAIRDGVTGWLVPPGDTLADTVSGVLKELDSDPERASEVKGACLAWAARFDWERTRNAMAQLAVRNSRAPGTRTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC89</accession>
    <name>C7QC89_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794266.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5679"/>
    <dbReference type="EnsemblBacteria" id="ACU74537">
        <property type="protein sequence ID" value="ACU74537"/>
        <property type="gene ID" value="Caci_5679"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5679"/>
    <dbReference type="HOGENOM" id="CLU_743336_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="372" mass="39226" checksum="C6C90835FBF3FC57" modified="2009-10-13" version="1">MGSVWGDSGGDGASDADSPGEPDPDELDLVVELVDDEPLPGEGPNAATSDRETIRSGEDWRGSVMARLRRLPRAIRLAGVCAVAAVFALAVWPTSGRREASPRPIPAPSQVNIDLYKVRLRTTTLETEYGADHAVLALSLTNSAATRLEVVSAELWDAVGTRLGSASMWPAEDLGAGTTVSVPVTLPYACDTYGFLPVLPITVRYNISTPQNPDTGHDYAYPLTSSIWDNYMRQRAAQCTSPDAQISASAIDTTQPIGAPSDPEGFDLTFTLESAGTTAWSVDKATVSSSGVTVTGEALPVAVNPGLTARIATHWHVENCDNPPRWSTQMEVEFTAHATGLPSGGSAAAAQTFIAELRPGLVTAMLYQACGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA3</accession>
    <name>C7QCA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794280.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5693"/>
    <dbReference type="EnsemblBacteria" id="ACU74551">
        <property type="protein sequence ID" value="ACU74551"/>
        <property type="gene ID" value="Caci_5693"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5693"/>
    <dbReference type="eggNOG" id="ENOG5033EQT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1412917_0_0_11"/>
    <dbReference type="OrthoDB" id="1968410at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="19542" checksum="B371585B14BC2248" modified="2009-10-13" version="1">MTSTAWFAEPLVLGLSGLMLWAGLEKLRSGSEFEATLAGVGVPRVFTPLLRWGLPAAEIAVGTTVALVPSALLPRIGVLILAAAFAIAGVQGLRATEKIACSCLGGTGDAALGWRQIAALPVWAAAVGAVSASHPPANGSDGPTRLAAAVLLMCTVRASTALRLARAARVNRVSFAEGIGQPASIFTYPQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS3</accession>
    <name>C7QCS3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796261.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7712"/>
    <dbReference type="EnsemblBacteria" id="ACU76536">
        <property type="protein sequence ID" value="ACU76536"/>
        <property type="gene ID" value="Caci_7712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7712"/>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045351_1_0_11"/>
    <dbReference type="OMA" id="GSIAIVH"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038424">
        <property type="entry name" value="H_kinase_PdtaS_GAF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022066">
        <property type="entry name" value="PdtaS_GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12282">
        <property type="entry name" value="H_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="302"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="509" mass="54735" checksum="8C0810D0DC65EC07" modified="2009-10-13" version="1">MNDLIHTRTDLDEADLDWLHLLIGDWQLLADLSFADLVLWAPLRTEDGADPGQAPLTEPGYVAVAQMRPNTGPTCYTADLVGSTIRRGQRPMLDLAIDSGRIRREGDPEWREDVPVRVEAIPVRRGDRVIAVISRNTNLLAARTPSRLELTYLQTAADLARMIAEGIFPYPESREQQDNSPRVGDGVIRLDADGAVVYASPNALSAYHRLGYAADMVGEHLGALTATLAPVQGAMEEALEVVASGRKPREAEVEGNGTVVQLRAIPLRPQGERTGALVLVHDVTELRRRERELISKDATIREIHHRVKNNLQTVAALLRLQARRIEDGTGRAALEEAVRRVGSIALVHETLSQTLDERVDFDEIADRVLAMVVDVGAGGPGGPGGVTVRAQRTGRFGVLPAQIATPLSMVLTEVLQNSLEHGLADQGGSLQVEAHRHGPRLCVVVTDDGNGLPPGFDAATAGNLGLQIVRTLVHGDLKGTFDLRPAPGGRGAVAVLDVEVGEVPAEPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ4</accession>
    <name>C7QCZ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785998.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1783"/>
    <dbReference type="EnsemblBacteria" id="ACU70704">
        <property type="protein sequence ID" value="ACU70704"/>
        <property type="gene ID" value="Caci_1783"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1783"/>
    <dbReference type="eggNOG" id="ENOG503361C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775428_0_0_11"/>
    <dbReference type="OMA" id="GRTAYWV"/>
    <dbReference type="OrthoDB" id="1997759at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="37172" checksum="2B33160E90F1A4C3" modified="2009-10-13" version="1">MTHDLKTSLEDLAEAEYADAPLSTIDIGRARADGRRRMRTARLAPVGGGVAVVAACALVVNGLGGASPAKSGGTPQQTGTAAGHSFTGTDPLPMIAKFGWLPAGFQTANRSAGPDYGDSLAAVTKPLPASGGAPAGADVIALMKSATEPTPLATETKAPASVTGSPKAFFITTPGDSSTIPPEVRLAWQTASGSWFVVNGDYRVRGDELKAQLLKVADSTTAEDSEAPLPIHVEGLPAGVTLGEAMLNDPATVGEGGFTMGLSYHSGNAGPGSGHYFSISVTPTGQQDPNQGSGSDPNAAAKSGLKGAPAVRTPNTCKDSEGLHICVQDDPAQSGPDPLASVGGAQGLLDRITSLGTDRANWTTHVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD39</accession>
    <name>C7QD39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786043.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1828"/>
    <dbReference type="EnsemblBacteria" id="ACU70749">
        <property type="protein sequence ID" value="ACU70749"/>
        <property type="gene ID" value="Caci_1828"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1828"/>
    <dbReference type="eggNOG" id="COG1090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047373_0_2_11"/>
    <dbReference type="OMA" id="YMPWIHI"/>
    <dbReference type="OrthoDB" id="1566711at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="252"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="31514" checksum="8AAA8B823D3AE0E2" modified="2009-10-13" version="1" precursor="true">MRIAITGSTGMIGTALSAALTEDSHEIVRLVRHTHPDETAGERHWSPFGEPDPKPYEGCDVVVHLAGAGLGDKRWSAAYKREIRESRVHGTDTLARSLAQLAEPPKALLSASAIGFYGDTGSTPVTEDSAGSEDFLGALCRDWEAATKPAEDAGIPVTHLRNGVVLGGSGGALARMLPFFKAGIGGPIGSGRQYFSFIGMADHLAALQHIMALTVDGNMTGAVNVTGPLPVTNRAFTKALGHVLHRPTVMPVPGFALRVLFGQMADELTGSQRVLPARLTESGFAFSTPDPRSALAAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI8</accession>
    <name>C7QEI8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786172.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1959"/>
    <dbReference type="EnsemblBacteria" id="ACU70879">
        <property type="protein sequence ID" value="ACU70879"/>
        <property type="gene ID" value="Caci_1959"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1959"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_11"/>
    <dbReference type="OMA" id="FHWYGRA"/>
    <dbReference type="OrthoDB" id="1377545at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="29879" checksum="29F5BB82353490F3" modified="2009-10-13" version="1">MTHARTVLITGATDGLGRALAHRLAAGGDTVLLHGRDQGRLDATADAIRDEHGVARPATFRADLAELAQVRELAAAVRGATERLDVLVSNAGIGSGEPDGRDRRESKDGYELRFAVNYLAGFLLTQELLPLLRASAPARVVNVASLGQQEIEFDDVMLEHGYSGIRAYCQSKLAQIASTVELAERVPAAEVTFNSLHPATYMPTKMVLQEAGHSIDSLETGVEATWRLVTDPKLAGVSGRFYDRQRESQALKQAYDTRARAELYQLSLKLVGLTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF50</accession>
    <name>C7QF50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pentapeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794537.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5950"/>
    <dbReference type="EnsemblBacteria" id="ACU74808">
        <property type="protein sequence ID" value="ACU74808"/>
        <property type="gene ID" value="Caci_5950"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5950"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068870_0_0_11"/>
    <dbReference type="OMA" id="GCTVYDC"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="30773" checksum="A6F6D9554559AADF" modified="2009-10-13" version="1">MQGNESTERAERKEHPERTERTSRADLAADCANCFALCCVGLAFTASQDFAVDKSAGTPCPNLAADDRCSIHTGLRGRGFQGCTVYDCFGAGQKLSRQTFGGVSWREAPHSAPQMFAALPVMRQLHEMLWYLAEAETLASASALRTEVGWSAEETERLSRLPLEDLLALDLSAHRAGVSELLSEVSTLTRAGIGGGRKKDRRGADLIGARLAGADFQGADLRGAYLIGADLSGADLRRADLIGADLRDAKLAGADLTGAIFLTQTQLNAALADQGTKIPDGLARPSHWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF77</accession>
    <name>C7QF77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794564.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5977"/>
    <dbReference type="EnsemblBacteria" id="ACU74835">
        <property type="protein sequence ID" value="ACU74835"/>
        <property type="gene ID" value="Caci_5977"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5977"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_13_1_11"/>
    <dbReference type="OMA" id="RVVAPCA"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="28688" checksum="E61D18961205375B" modified="2009-10-13" version="1">MPVSPVLVPLPGARSPRDPQRAIKRGPSRVPREQVAATQRDRLYDGLVRTVAERGYANASVSDICRVSGVTRPAFYEHFESKQGAFLAAYRHGTDVLFAMLRHAFLEETDAADGDALCPLPESAAEVQTWTRATCAVLAVLLDVLASVPAFATAAIVEIDAVGPEGRQARSEQLRDFEAFFALAPATPDGVDRGEVVNSVVAGAYGTLYRHIAAGRAAELPHLLPALVYFVVAPFAGPEIAAKASHAALADHPRSVAPCVPAQAETGVGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFE6</accession>
    <name>C7QFE6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_7900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM175 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7900"/>
    <dbReference type="EnsemblBacteria" id="ACU76723">
        <property type="protein sequence ID" value="ACU76723"/>
        <property type="gene ID" value="Caci_7900"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7900"/>
    <dbReference type="eggNOG" id="COG3548">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090238_3_0_11"/>
    <dbReference type="OMA" id="ADIRFAF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010617">
        <property type="entry name" value="TMEM175"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06736">
        <property type="entry name" value="TMEM175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23133" checksum="FED704101F76A833" modified="2009-10-13" version="1">MGTVPESSEDDPDAEGSVQSPDRLITLADGIFAIAMTLLVLNISVPSGLDHDHFRSSLHETWSRLATYALSFAIIGGQWLDHHRVFRLVKRTNTVVVRLTLLLLGLVALLPFPTALLSDYGGHEPLAVVYYAVTVGAINLLLLGLFLTVRNDERLQARPISDRFARGMIADCGATIAIAAVAVLVALTVSAGAGLFTWLAAFPAGMASRRLRKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFU8</accession>
    <name>C7QFU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-3-methyladenine glycosylase I</fullName>
            <ecNumber evidence="1">3.2.2.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.20" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2005"/>
    <dbReference type="EnsemblBacteria" id="ACU70925">
        <property type="protein sequence ID" value="ACU70925"/>
        <property type="gene ID" value="Caci_2005"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2005"/>
    <dbReference type="eggNOG" id="COG2818">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083758_0_0_11"/>
    <dbReference type="OMA" id="YVAYHDT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21028" checksum="A467F9127431E3BD" modified="2009-10-13" version="1">MGDVQDLVTGEDGIPRCGWAGTGGDYAAYHDTEWGRTLHGDDAMFERLSLEGFQAGLAWITVLRKREAFRKAFKDFQIDAVAALTPADVELLLTDPGIIRSRAKIESAIHNARIVRDFPEGLDAYLWNFAPPTHRRPTSFGQTPTETPESKAMAKALKKAGVKFIGPTSAYALMQATGMVDDHLTGCFRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFZ5</accession>
    <name>C7QFZ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Plasmid maintenance system antidote protein, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2052"/>
    <dbReference type="EnsemblBacteria" id="ACU70972">
        <property type="protein sequence ID" value="ACU70972"/>
        <property type="gene ID" value="Caci_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2052"/>
    <dbReference type="eggNOG" id="COG3093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032305_1_0_11"/>
    <dbReference type="OMA" id="CNGDAVP"/>
    <dbReference type="OrthoDB" id="1502873at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="38780" checksum="376AF171B5B624A2" modified="2009-10-13" version="1">MARHTDAFAARLSELKDRSGRSYGALAQRLHTSTSTLHRYCNGTTVPAEFAPAERFARACNATPEEVLALHRMWLLADAERRAEATGSGITESQSGASATGVVASGTADSAAPGRRTRRRLIPALAGLAAVAVLVPIAIYATRDSNSPISKPSAPSPSPTPTLPTPVTVSVLADNWDTECGQWFYAPQSPTAVPPPPGLPDVGLWAQPLGAVPGGHLRLQLTAQGTPGRAPVVLHTLYVHVVGAKPAPASGYAYTMGSGCGGGLDPASFAIDLDASAPKIKPVSGQIANDKVGLADFPFQVSGDDSQVLDVDAHSADQEIDWTLVLVWSCGDQQGTLTVDDHGKPFRTIGLNGKPAYFYNGTKWAATTLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFZ9</accession>
    <name>C7QFZ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF853 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786269.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2056"/>
    <dbReference type="EnsemblBacteria" id="ACU70976">
        <property type="protein sequence ID" value="ACU70976"/>
        <property type="gene ID" value="Caci_2056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2056"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028164_2_0_11"/>
    <dbReference type="OMA" id="TTEYGNI"/>
    <dbReference type="OrthoDB" id="600220at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033186">
        <property type="entry name" value="HerA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05872">
        <property type="entry name" value="DUF853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF853" evidence="2">
        <location>
            <begin position="58"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="552" mass="58197" checksum="8C5C689C0F55C58A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG43</accession>
    <name>C7QG43_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786313.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2101"/>
    <dbReference type="EnsemblBacteria" id="ACU71020">
        <property type="protein sequence ID" value="ACU71020"/>
        <property type="gene ID" value="Caci_2101"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2101"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_4_11"/>
    <dbReference type="OMA" id="ANTWIRA"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="45646" checksum="E92B5681B479A3AA" modified="2009-10-13" version="1">MLTAIVSRPEVGILDADTGGWGSMADSDKEPLPRLFWWFFAAGAVSWLGDGVIVVGFPLLAAGITGSPLGIAAVVVTQRLAPMLLSLPAGALADRWNARLTAVSTNVAQALLFAVAAILVAGNHIGLASLIVIAFLADACGTLFTCANGAMLADVVEPKHYGAANTWIRAANTLIAFVIGPGVGGLLYATGRQLPMIIDACSFVAAAAVLSTLRLPNARPRPERADRHFLTEVKEGARISFGPGPMRLMAAVIGTMTLAQAGSVAAIVVLGTHTVGLSKTGFGWTLAAGNVAAVAVMLSIGRLAKLRTSSAVLVSLVFGIIGEILLGTARSGPQISVGLAMDASAVLIIGVTLATARMRLVPREMLGRMTGGYQTIMFGAGAVGTIIGGALAESSGRLPYLVCAAVYAVVLATCFRRMRGLDPQPEAAVSIPAQGAAEGVAAVEAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG54</accession>
    <name>C7QG54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4031"/>
    <dbReference type="EnsemblBacteria" id="ACU72899">
        <property type="protein sequence ID" value="ACU72899"/>
        <property type="gene ID" value="Caci_4031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4031"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_6_0_11"/>
    <dbReference type="OMA" id="IICVGEM"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="99"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="47364" checksum="8D1D1F094B69D453" modified="2009-10-13" version="1" precursor="true">MSVATFEREALTDDEQHLVRKLRASVGARLAERVGDNSGSVERERVGRELIDDALMAHARAGLAGGGRDVLDGQAEAKVSRAVFDALFGMGGLQRWLDDPSVENITANGFDHVFVHYSDGSKVPVGPLAASEEDFVDLLRTIAARAGTEERIFDRAHPQLNIQLPDGSRLFAVMAVSRRVSLTVRKHRHMATSLRELAALGMFDLDIAAQLEAAVRAKLNILICGAMGGGKTTVLRGLAACIGPEERLVTIEDTYELGLEQAHPDVVAMQAREGNLEGQGAVSQAELVRMSLRMNASRVIVGEVRGEELVPMLNAMTMGTDGSLGTIHASSSKQAFDKMATYAIQSPERLDRAATNLLVGTALHVVIQLGRLRDGTRVLSSIREITGVGDNGEVTSNEVYKPGRDGQAVPGTGWTAGTAQRLIDAGLDEDVLTRSARAGWSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGC5</accession>
    <name>C7QGC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4106"/>
    <dbReference type="EnsemblBacteria" id="ACU72970">
        <property type="protein sequence ID" value="ACU72970"/>
        <property type="gene ID" value="Caci_4106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4106"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014290_1_0_11"/>
    <dbReference type="OMA" id="FIHMVSR"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="536" mass="58771" checksum="DDE48C1BED87FE42" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGF5</accession>
    <name>C7QGF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Curculin domain protein (Mannose-binding) lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792729.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4136"/>
    <dbReference type="EnsemblBacteria" id="ACU73000">
        <property type="protein sequence ID" value="ACU73000"/>
        <property type="gene ID" value="Caci_4136"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4136"/>
    <dbReference type="eggNOG" id="COG2503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019346_1_0_11"/>
    <dbReference type="OMA" id="STIQGKW"/>
    <dbReference type="OrthoDB" id="323324at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="SSF51110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983121" evidence="1">
        <location>
            <begin position="37"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="433"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="57295" checksum="B3AF92F80BD23E80" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG2</accession>
    <name>C7QGG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792736.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4143"/>
    <dbReference type="EnsemblBacteria" id="ACU73007">
        <property type="protein sequence ID" value="ACU73007"/>
        <property type="gene ID" value="Caci_4143"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4143"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="VWPRIAN"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="19982" checksum="E56670FF81BFF932" modified="2009-10-13" version="1">MALTEHEEQAFWQFVANRRQHLVRTAYLLAGDHGHAEDFVQDALIRAHRNWRRIERADQPEVYVRRIIVNLANSWWRRALRHRTHVAWEPPDRPDERDGHAAVEREDELWRALATLPAGMRAVVVLRYYEDLSEAETAAVLGTSLGTVKSQASRGLVRMRAALSESRADLATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH47</accession>
    <name>C7QH47_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PLDc_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8074</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796622.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8074"/>
    <dbReference type="EnsemblBacteria" id="ACU76897">
        <property type="protein sequence ID" value="ACU76897"/>
        <property type="gene ID" value="Caci_8074"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8074"/>
    <dbReference type="HOGENOM" id="CLU_113604_4_1_11"/>
    <dbReference type="OrthoDB" id="2063795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="8">
        <location>
            <begin position="13"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="14967" checksum="8A6986FB860A8828" modified="2009-10-13" version="1">MLRFVIQWLVPIALAIFAWVDCLLTPRPWVRFLPKPVWAVLIAVPYVGALLWIFSGRTAQPRDPRRRATDSHPGLLSSIGRGGAHQARPRIVDTPGRRTRGGSAPSTWTVAPDDDPEFLRQLGEQLKKDRPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR2</accession>
    <name>C7QHR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2168"/>
    <dbReference type="EnsemblBacteria" id="ACU71087">
        <property type="protein sequence ID" value="ACU71087"/>
        <property type="gene ID" value="Caci_2168"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2168"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_59_0_11"/>
    <dbReference type="OMA" id="PWLRYRN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="214"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="34882" checksum="C668A794560E65A2" modified="2009-10-13" version="1">MRVVFLLIPRLHLLDLSGPAQVFSTADDLGFPYELRYCAEQEDIVSAQGVRLRAETAWPGAGPEDLVMVPGWRSPTLKGGPRPGRGLLARLVAHHAAGGTVASVCSGADVLGQAGLLDGRRCTTHHDLRDELAARYPRARVERDVVYVADGRVVTSAGIASGIDLALHLVAERHGPAAAARVARDMVVYARRSGEESQDSAMLRHRWHLRDAVHRAQDRIDANYAEPLRLTDLARAGGVSERTLTRQFVESTGMTPLRYQQTLRLERAEHLIGHGATVEAAAHAVGFADARMLRRLRSRVMEDTPFAPSHGATTSPRIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHU0</accession>
    <name>C7QHU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MgtC/SapB transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2196</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786408.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2196"/>
    <dbReference type="EnsemblBacteria" id="ACU71115">
        <property type="protein sequence ID" value="ACU71115"/>
        <property type="gene ID" value="Caci_2196"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2196"/>
    <dbReference type="eggNOG" id="COG1285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1136444_0_0_11"/>
    <dbReference type="OrthoDB" id="2076552at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="24859" checksum="F2414202EF89BBD3" modified="2009-10-13" version="1">MHSVGSVLLAAVPSADNIHVPTHWDAVGRIALAWALTFALGFERQIRGAMAGDRTFSLLGAATALIGVLAGNGASTILAGAVTGIGFIGGGLCFRQTVQEHEVLHGITTAASIFACSAIGAACGLGLVKESITATAATLLTLELRHIPLIRTLDARRWNGLVHHDEHVHSQILKRGTRISSQMAEARVATADTADSDAVVLINPVIAAQQAAAATAATVMPEAPVMVDAVAADSGAAATPAGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV1</accession>
    <name>C7QHV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786419.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2207"/>
    <dbReference type="EnsemblBacteria" id="ACU71126">
        <property type="protein sequence ID" value="ACU71126"/>
        <property type="gene ID" value="Caci_2207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2207"/>
    <dbReference type="eggNOG" id="COG3336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054944_1_0_11"/>
    <dbReference type="OMA" id="MNTVAMA"/>
    <dbReference type="OrthoDB" id="1553593at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019108">
        <property type="entry name" value="Caa3_assmbl_CtaG-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09678">
        <property type="entry name" value="Caa3_CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="325"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="387" mass="41174" checksum="FEA0E9D6E2EF6727" modified="2009-10-13" version="1">MVTPALTAVPLPAPLGESQVGSAWRLNPYVGAILLVIAALYVAGTVVVRRRGGHWPLYRTVLFLLGLVLFAWTTMSFLAVYQQVMFWPRAVQIITLLMVVPLFLALGMPLTMAIEGGPRRLAALVRWVLATRIAALLTFPAVVSIVFLVTPFTVYFSPIYEDTLRSRGAAWVLSFALSALGFFYYWTRLRLDPVPKEYPHLVSVWITFAEAIADGALGLTLMLGHHLVAGDWYTALNRPGGLTPKQDQVWGGGALWLIGDLAGVPFLGALWRRMFDEDRDRAAEVDAELDALEAEGAIVYGTASGSGGGVGAGVGVGGGGVGSGGAPSVGGGADAQDDVDASSPASISHTSPATVGAAPAGEEAKRTRPWWETDPVLGRRMGFLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI70</accession>
    <name>C7QI70_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4251</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792844.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4251"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73115">
        <property type="protein sequence ID" value="ACU73115"/>
        <property type="gene ID" value="Caci_4251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4251"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_5_1_11"/>
    <dbReference type="OMA" id="VEVWPMP"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983158" description="Beta-N-acetylhexosaminidase" evidence="5">
        <location>
            <begin position="27"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20b" evidence="7">
        <location>
            <begin position="43"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="6">
        <location>
            <begin position="174"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="528" mass="54845" checksum="F2E922965F2984E0" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE4</accession>
    <name>C7QIE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6167</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6167"/>
    <dbReference type="EnsemblBacteria" id="ACU75021">
        <property type="protein sequence ID" value="ACU75021"/>
        <property type="gene ID" value="Caci_6167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6167"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038683_1_0_11"/>
    <dbReference type="OMA" id="LAQWGPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="41939" checksum="3EC3A4CA742DF2F4" modified="2009-10-13" version="1">MATPPRTHKETWSRAALALTAVGWGANQFAPMVLLYRERMGVSASAAEAIFGLYAAGLVPGLLIAGPLSDRVGRRPVVAFAVLLSMISGVVLMLGSHGLGWLSTGRVLMGIASGAAFSAGSAWVKELSATNAVAGAGARRASIAMTAGFGIGPLIAGVLVQWGPAAYEVPYIPQLILAAAALFLLAGTPETVQRWPSGILGGGLLRLRGFSDRRFVGVVLPMAPWVFGAATIAMVYLPGLSASHVKGISLVFAGTAAMVTAMSGVAIQPFARRVAASPAGQDRARPRLLTLGLALVTVGTLAEAGVAALNSLGAWQAVLTLVVAVVMGFGYGILLVFGLAEVQRLAPPEDLAGMTAVFQAFTYLGFAAPYLLSALKNVASPSTLLLAVAALGVLTIAVTVRNARVTAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIH4</accession>
    <name>C7QIH4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_6197</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in acetate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>acetyl-CoA + phosphate = acetyl phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19521"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">In the N-terminal section; belongs to the CobB/CobQ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="5 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6197"/>
    <dbReference type="EnsemblBacteria" id="ACU75051">
        <property type="protein sequence ID" value="ACU75051"/>
        <property type="gene ID" value="Caci_6197"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6197"/>
    <dbReference type="eggNOG" id="COG0280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0857">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019723_3_0_11"/>
    <dbReference type="OMA" id="FFMCLAD"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016475">
        <property type="entry name" value="P-Actrans_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006107">
        <property type="entry name" value="PhpActrans_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="13">
        <location>
            <begin position="219"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="PTA_PTB" evidence="12">
        <location>
            <begin position="378"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU75051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="714" mass="74994" checksum="95DFA83A6077FC00" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ0</accession>
    <name>C7QIQ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8127"/>
    <dbReference type="EnsemblBacteria" id="ACU76950">
        <property type="protein sequence ID" value="ACU76950"/>
        <property type="gene ID" value="Caci_8127"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8127"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313577_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="23144" checksum="8FC641600220627F" modified="2009-10-13" version="1">MRTVTDIDTIKALADPTRLAILRSLSRDRVPKSAKELAEDLDQPQTKLYRHLKVLQEAGLIEAAETRVVSGIVETKYRAMQAGLSINPGENIDATREAMHDIIAGSLNDYRDRMLRAVELDLPELDEESAKKRGIVMNLSATVSEANADDFQQRLEALIAEFDDFPRDPDGVRVEGLVSWFRPKPAGQTDQTDQTGQTEDRPDPGSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV9</accession>
    <name>C7QIV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796734.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8186"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77009">
        <property type="protein sequence ID" value="ACU77009"/>
        <property type="gene ID" value="Caci_8186"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8186"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_943183_0_0_11"/>
    <dbReference type="OMA" id="QNCEDND"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="32976" checksum="CFB10A6B7F73045C" modified="2009-10-13" version="1">MTTLDIMLPYYGDVALMQTAVRSVIAQSDPDWRLTVVDDGTEPGVPEWFAALDDPRVRYQRNEQNLGVTGNFNKCLELAKCDYMVMMGTDDVMLPGYVAQIRRIAKEFPGVGIIQPGVEVIDSAGRVVNTIADQAKARIYLPRFTGTVLMGGEELAASLLRGCWFYFPSLCWRTEAIKKASFRADLDIIQDLAIVIDLIEAGATMALSDELAFQYRRHEASVSSVEAMAGKRFAEARRYFVGAAAQMDALGWPKAAKAARRYTASRLHAVTLLPSALKARSAPGVRNLARHAFLPAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJC7</accession>
    <name>C7QJC7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease V</fullName>
            <ecNumber evidence="1">3.1.21.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Deoxyinosine 3'endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Deoxyribonuclease V</fullName>
            <shortName evidence="1">DNase V</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nfi</name>
        <name evidence="2" type="ordered locus">Caci_2231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the endonuclease V family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.7" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2231"/>
    <dbReference type="EnsemblBacteria" id="ACU71150">
        <property type="protein sequence ID" value="ACU71150"/>
        <property type="gene ID" value="Caci_2231"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2231"/>
    <dbReference type="eggNOG" id="COG1515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047631_1_1_11"/>
    <dbReference type="OMA" id="RIHFRQA"/>
    <dbReference type="OrthoDB" id="1681607at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043737">
        <property type="term" value="F:deoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00801">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with target DNA" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23500" checksum="5AB2F1401E3CDE31" modified="2009-10-13" version="1">MLITHEKWPRTAQDAEAEQERLAGSVDVSTPLAPFRYIAGLDVAYAIDSSRVAGAVVVLDADTLAVEDMATAVMDVEFPYVSGLLAFREMPALITALGRLSVDPDVLVCDGYGIAHPRRFGLACHLGVLAGKPAMGVAKTAFVGQAAEPGIQRGEAADLVHGGEVVGAVLRTQLSTKPVFVSPGHLITASDATRLALRLATKYRLPETTRLADQLSRRALAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJQ3</accession>
    <name>C7QJQ3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ordered locus">Caci_2358</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786569.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2358"/>
    <dbReference type="EnsemblBacteria" id="ACU71276">
        <property type="protein sequence ID" value="ACU71276"/>
        <property type="gene ID" value="Caci_2358"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2358"/>
    <dbReference type="eggNOG" id="COG0503">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063339_3_0_11"/>
    <dbReference type="OMA" id="KPGIVFR"/>
    <dbReference type="OrthoDB" id="1532478at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="49"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="19541" checksum="CE68BBC5499BD1A9" modified="2009-10-13" version="1">MSFPENPSGEDLSKVLATRILDVPDYPKPGVVFKDITPLLGDPESFALVVGAMAEQVRAAGATRVAGLEARGFILAAPVALAAGVGFVPVRKAGKLPRATYREDYVLEYATATIEVHRDAFAPGERVMIVDDILATGGTAVAAANLVRDAGAVPVGLSVLMELDFLQGRRRFAKAVPDAGIATLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJQ6</accession>
    <name>C7QJQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792873.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4280"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73144">
        <property type="protein sequence ID" value="ACU73144"/>
        <property type="gene ID" value="Caci_4280"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4280"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044209_0_0_11"/>
    <dbReference type="OMA" id="WADPRDN"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982953" evidence="3">
        <location>
            <begin position="33"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="373"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="51723" checksum="9E1A7847EE5CF0E2" modified="2009-10-13" version="1" precursor="true">MRHPLVRLRRTTLVLAAGALAVAATSGFAAYAAAASPAAAAAATQSAPSAAAPPSSFHGVNWADPRDNYASDAVVPSGLSVTDDYRTVYRTTQKMVDGFRTNLGANTLRLPINPASVGTAWWKSYRATIDAATASGDKVILSYWESPTAKDGKIDDVATWNQMWDTVTAEYRTNPRVYFEPMNEPFGYTLDQWVQVCTGWLAQHADVPRDHVVISGTGYNDNVTGVGATQALSGTLLSLHFYGYWASATTEADWISNLLPRIGGYASRTIIDEAGSPMTVGLNYGNHNGNVFTAYFAAVTDIARGMGMGMVYWPGLRTGDSYSIESLDAKGYLQNNSASGVAQLKWGYGLGTVPPVNDQPPAPAGTQVTETASGRCLDVPGYSTTSGTQLDLWDCNGGGNQSWDYTATHLLTVYSTKCMQAGTGTGTVTAGAAVVIEDCTGLPAQQWTVAANGTIASAADASLCLDTTGSASADGSTAVVAACSGSASQNWKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK05</accession>
    <name>C7QK05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792972.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4379"/>
    <dbReference type="EnsemblBacteria" id="ACU73243">
        <property type="protein sequence ID" value="ACU73243"/>
        <property type="gene ID" value="Caci_4379"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4379"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_11"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="423"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="506" mass="54593" checksum="4FF04B44C1094E0C" modified="2009-10-13" version="1">MTFNLATILRESRLASPGKPLCHSQQATLTYEQVDEASGRMAAALLALGLRRGDRVAVQLPNLPEFIVSYFGILKAGLIMVPLNPLLKGREIAYHLRDSGSTILVAFSLLAAEAVAGAEEAGGTAVYVVSPPGHDQIPPGTKPFAELLDAADTGDIAPTNADDTAVVLYTSGTTGKPKGAELTHFQLYMNCTVSGDLFGIRPDDVSLAVLPLFHVFGLSSVLNVAVRNAGTMALVPRFEIEPVLDAMEKHRCTIFSGVPTMYFALLHADTAERDLSALRVGCSGGAPIPGEVIRAFEEKFPGVVILEGYGLSESASTTTFNISAEQRKVGSIGKPVWGVETRVVDDAGRTLPPRPEHVGEIVIRGHNMMKGYWGNPEATAEAVRDGWFHTGDLGYADEDGYFYIVDRKKDMVIRGGFNVYPREVEEVLYTHPAIAEAAVIGRADERLGEEVVAYVALKAGAHADEQDVIAFCRDRMAPYKYPREVRFLSALPVGPTGKILKKELRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK30</accession>
    <name>C7QK30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794833.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6250"/>
    <dbReference type="EnsemblBacteria" id="ACU75104">
        <property type="protein sequence ID" value="ACU75104"/>
        <property type="gene ID" value="Caci_6250"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6250"/>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_13_2_11"/>
    <dbReference type="OMA" id="FRTATWG"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="243"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="433" mass="45803" checksum="37A0F993C94F5EAB" modified="2009-10-13" version="1">MTSTVGQEREQELAAAATAPQPASLWRNHDFLKFWSGETLSLFGTQITTLAIPLTAVLVFNASPFQVGLLRFLQLVPYLALAMLFGVWVDRARRKRVMMLANGARMVLIAAIPLLSATHHLTLGLLLAIACAVGVFSVLFDVSWMAFVPALVKEPKQYVEANQKLGVTSSSADVAGPGVAGAVISALSAPTALAADAISYLFSLATLLWIRTPEPKAPPTTTKRRLRTELVEGLRFVFGDRILRPLALIAPFCNFVMVGVWTMFLLYASRGVGLSSAQIGVVFASSSVGGLVGATVSRRLLQRFRLGRVYAVSMSAIFLAPLLIPLATGSRPVLLATFIASFFLAYLGLGVANVVVISLRQASTPQHLMGRMNAAFRTALFGGGSLGGLVGGLISGAAGLRSGLLVVAVGSAVMVLPVLLSPVSRLRAMPTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK45</accession>
    <name>C7QK45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794848.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6265"/>
    <dbReference type="EnsemblBacteria" id="ACU75119">
        <property type="protein sequence ID" value="ACU75119"/>
        <property type="gene ID" value="Caci_6265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6265"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_0_0_11"/>
    <dbReference type="OMA" id="HDGFGDR"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983277" evidence="1">
        <location>
            <begin position="33"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="45"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24334" checksum="52395D66A8317B9B" modified="2009-10-13" version="1" precursor="true">MIIGFSRKVGALLVAAVLALLAIGFSAAPAAASSKAAAGKAVTSKVVYITFDDGPSPVYTPKVLKVLAQYGVHATFFEVGQNVAAHPSVTTRVYRAGNSVQNHSWSHPDLRKLSASQFAYQVNATDRQIRAHTGYRPCCLRPPYGAVNGAVRSRTAALGKKIALWTVDPRDWSRPGASAIQARVLSHVRPGSVVLLHDGGGDRSQTVAALSGILRTLKARGYTFATWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE9</accession>
    <name>C7QKE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796773.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8225"/>
    <dbReference type="EnsemblBacteria" id="ACU77048">
        <property type="protein sequence ID" value="ACU77048"/>
        <property type="gene ID" value="Caci_8225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8225"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1141587_0_0_11"/>
    <dbReference type="OMA" id="IVETIAW"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24736" checksum="A3EBB2B9914A4E87" modified="2009-10-13" version="1">MRGRLPARPLAEVADAAVRVFITKGFRSAGISDVAGELGLSHGAVYTYADSKQALLYLALLRVLDPEAAAELATPVVAPPMERIVEAVKTWTAARGGLGGVDALLAKAPAESAGPARDELAQVVDGLYGFIEDNSVPLKLFARCAEDLPELAAWYYVQTRRGLLEALGGYLRARIDAGVLRPVPDVPVAARFIVETIAWFAMHRHGDPDSAMLGDADCRRSVRDLVAASFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKQ8</accession>
    <name>C7QKQ8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8334"/>
    <dbReference type="EnsemblBacteria" id="ACU77157">
        <property type="protein sequence ID" value="ACU77157"/>
        <property type="gene ID" value="Caci_8334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8334"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902219_0_0_11"/>
    <dbReference type="OMA" id="PTHRSIV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33017" checksum="8EC88E89F8E35522" modified="2009-10-13" version="1">MNPSLEPRSRAGRAARSFHGRYAQPISHQPLPQAVANLPTHRSIVVVDVVSFTRPDRDNVDQLAIRAALYETLRDAFEDSGIPWRQTVREDRGDGVLIFISAEVSKVLLLGRMPARLAELLERGNTKRSARQRFGLRVVVHAGEVHHDAHGYAGYDVNLAFRLVDACPLREAMEHSAATVGLIVSEGVHDGVLRHGYGGLDVAAFEQVRVQVKSADVPGWIQLFGGGSVLPVPLQVVRSVPETEPAAIAGRGGEGPVAVLLADEASLLDELAGLGVRTVVLVGGAAGLAAGLASIARQPIYIDHEFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVR6</accession>
    <name>C7PVR6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-dehydroquinate synthase</fullName>
            <shortName evidence="8">DHQS</shortName>
            <ecNumber evidence="8">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroB</name>
        <name evidence="10" type="ordered locus">Caci_2390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786601.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2390"/>
    <dbReference type="EnsemblBacteria" id="ACU71308">
        <property type="protein sequence ID" value="ACU71308"/>
        <property type="gene ID" value="Caci_2390"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2390"/>
    <dbReference type="eggNOG" id="COG0337">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001201_0_3_11"/>
    <dbReference type="OMA" id="YGVIWDA"/>
    <dbReference type="OrthoDB" id="1677032at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="9">
        <location>
            <begin position="68"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="72"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="106"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="170"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU71308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="370" mass="39206" checksum="553166A056C855ED" modified="2009-10-13" version="1">MTSETRIKVGGELPYEVVVGHGLLGELPAMIGSKAARVAIVHPRALAATAEAVRDDLIEHGGYQALTVEVPDAEEAKSVGVLAYIWEVLGKSNFTRTDAVVGLGGGATTDLAGFAAATWLRGVRVVQIPTTLLGMVDAAVGGKTGINTAEGKNLVGAFHPPAGVLCDLDTLQTLPQNDFVAGLAEVVKCGFIADPEILRLVEADIEGAKRFDGPHTRELIERAIAVKADVVSSDLKEAGRREILNYGHTLGHAIERNERYRWRHGAAISVGMIFAAELGRVAGRLDEATADRHREILTALGLPTAYDGHAWPKLLETMRVDKKSRADMLRFIVLDGLAKPAVLEGPDPALLVAAYSEVAAEPSAKGAVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW89</accession>
    <name>C7PW89_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4474"/>
    <dbReference type="EnsemblBacteria" id="ACU73337">
        <property type="protein sequence ID" value="ACU73337"/>
        <property type="gene ID" value="Caci_4474"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4474"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030803_0_0_11"/>
    <dbReference type="OMA" id="NHASARC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980407" evidence="2">
        <location>
            <begin position="43"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="569" mass="59839" checksum="F971A3C713A118C4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD0</accession>
    <name>C7PWD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793107.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4515"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="EnsemblBacteria" id="ACU73378">
        <property type="protein sequence ID" value="ACU73378"/>
        <property type="gene ID" value="Caci_4515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4515"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_1_1_11"/>
    <dbReference type="OMA" id="AGWAVRY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="369" mass="38508" checksum="8E3B47E9B78E6449" modified="2009-10-13" version="1">MSTEPGEIVSHAVGSGVVPGAVLAYGRGTDGPVHVSAFGAGVGPDTVYDLASLTKVTVTLPCVLRLVEAGEIGLDDPVARYLPDFGKEQVTIRHFLTHTSGLPAIREVWRLPGSAHERFAAVLAEPLESPVGTVVKYSDLGFIMLGQIVADLTGKPLQEAFGELVAAPLGMTSTGYLPAGPAAATEANWFDDPERQDPKSGVVHDENAESLGGVAGQAGLFGTASDLAIYLRAGWLAEDSPILTPATRAEALRCQTEGLDGRRGLGWTLRGDSFDFMSDQWPLTGAGHSGFTGTSLAFDPVAEIWCVLLTNAVLYGRGNRARQLRRSLHGAVAAAFGVAEKPDDVGEDGSGRSLNSSDGDPGTGFRITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWX7</accession>
    <name>C7PWX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xanthine/uracil/vitamin C permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8411"/>
    <dbReference type="EnsemblBacteria" id="ACU77234">
        <property type="protein sequence ID" value="ACU77234"/>
        <property type="gene ID" value="Caci_8411"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8411"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_0_11"/>
    <dbReference type="OMA" id="YVDIIDC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="463" mass="47972" checksum="4ABF5AAA3A7BE79B" modified="2009-10-13" version="1">MGVLERVFKVHERGSSYVREVRGGLATFFTMAYILVLNPIILGGTKDKFGHVLSHTQLVTSTAVVAGVMTLIMGIGGNLPLAIAAGLGLNGVVAFTLAPTMSWPDAMGLVVLEGLGICLLVVTGFRQKIMDAIPLALKKAIGVGIGLFIAFIGLVDAGFVGAGSGTPVTLGAGGTLKGWPMFVFCVGVLLTLSLLVRRVPGGLLISIVTTTVLAIVVNKIATVPDKDWGTIAPKVPHGVVAHPDFGLLGKFSLFGGFHHAGVMTAIVFVFTLILADFFDAMGTIIGISGEAGLLDEDGRLPGIGRVLFIDGLAASAGGAGSASSNTCFVESAAGVGEGARTGLANVITGALLFLAAFLTPVLTIVPSQAAAPALVAVGFLMMTQVKDVDWDDWEIAVPAFLTIALMPFTYSITNGIGAGFILFCVLKVVLGKARDVNWLMWIVAAFFVVYFALDPIKQALGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWZ9</accession>
    <name>C7PWZ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ordered locus">Caci_8433</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796981.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8433"/>
    <dbReference type="EnsemblBacteria" id="ACU77256">
        <property type="protein sequence ID" value="ACU77256"/>
        <property type="gene ID" value="Caci_8433"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8433"/>
    <dbReference type="eggNOG" id="COG0221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073198_1_1_11"/>
    <dbReference type="OMA" id="DEPTFPG"/>
    <dbReference type="OrthoDB" id="1767807at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="19911" checksum="05D256FEE5E12882" modified="2009-10-13" version="1">MEFDVLIEIPKGQRNKYEVDHKTGRIRLDRMLFTSMVYPTDYGFIEDTLSLDGDPLDAMVLLDEPTFPGCLIRCRAIGMLNMADEAGGDDKILCVPATDPRFEHLRDYHHISEFERQEIQHFFTSYKDLEPGKEVHHAEWQNRSQAETEIRRSYKRFEDLPEEEKVHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX12</accession>
    <name>C7PX12_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796994.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8446"/>
    <dbReference type="EnsemblBacteria" id="ACU77269">
        <property type="protein sequence ID" value="ACU77269"/>
        <property type="gene ID" value="Caci_8446"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8446"/>
    <dbReference type="eggNOG" id="ENOG5032X03">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166919_0_0_11"/>
    <dbReference type="OMA" id="DANRTAW"/>
    <dbReference type="OrthoDB" id="1708502at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="117" mass="13518" checksum="22CAEBD573E92E48" modified="2009-10-13" version="1">MSPKRHDDVAPPVVEGEWRIRYANTESVDGWRDLCGKAPGNTRRAYETIRSNPRPTEPTARHHQLKYELAFVVRGGVRIEHWQYEVTGAGRIWYHIDVVKRTLWLDFAGLGHPKATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXB9</accession>
    <name>C7PXB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0527"/>
    <dbReference type="EnsemblBacteria" id="ACU69470">
        <property type="protein sequence ID" value="ACU69470"/>
        <property type="gene ID" value="Caci_0527"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0527"/>
    <dbReference type="eggNOG" id="COG3208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070456_1_2_11"/>
    <dbReference type="OMA" id="RLFVFHH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29337" checksum="9292BE2CEF44B24E" modified="2009-10-13" version="1">MTGAHSDKVGGGTVGGPRPAEPELRLFLFHHAGGSSSVFEGWESRFPAGWDVRALDAPGRGAARSAKPCTTVEELAGYFRDHLSLSFDRPFSFFGHSMGAMVAYELARRLQAEGGPQPNWVGLSACRAPGQPAARGQHGLSNEDLRAWLAAAGGTDQLVLHHPLIWKMLEPLLRADLRVVDSWQPTVDAVPLRGALSVFGAQDDRVLAHEKLIGWQPFTEHYVASRLFRGGHFYLQRQADLIIRWIVADISGSRRVCATPWTSPAKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXC2</accession>
    <name>C7PXC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tryptophan halogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0530"/>
    <dbReference type="EnsemblBacteria" id="ACU69473">
        <property type="protein sequence ID" value="ACU69473"/>
        <property type="gene ID" value="Caci_0530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0530"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_4_0_11"/>
    <dbReference type="OMA" id="RFVDPIF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="491" mass="54201" checksum="426C244BB62CC2BE" modified="2009-10-13" version="1">MTEQNTVKTANDVDNPDNAEKTRVLVIGGGPGGSTAATLLARQGIEVTLLESAIFPRYHIGESILPSVLPVLDLLGVREEVDNHGFVRKDGAYFEWGPENWDLNFDHLSGASRHSYQVIRSEFDHMLLKNAQAKGVDVREGVKVTEILFHGDRPVAARWSASDNSGAAGTIAFDFLVDASGRAGVMATKYLKNRRYHEAFKNVAVWSYWRDVKPLEVGPKGAIAVCSVPYGWFWAIPLHDGTTSIGLVAKRTTFSDERERLGSIEAVYADAMTQAPRILEMTQGANKIEGYKVEQDYSYVSERKSGPGYVLVGDAAAFLDPLLSTGVHLSTFSALLAAASVSAVLDGELAEQEAVDFYERAYHQAYERLLVVVSFFYNSYNRQTQFFEADKLTRRERHMLNLYESFLHIVTGIEDLDDSIDGGEALEEVAQQIATQKKIDAGHNEAMNSLPDSPRQAVGGLYLELEPRLRIRRTSEAPAGPEPVREARAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXG7</accession>
    <name>C7PXG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71420">
        <property type="protein sequence ID" value="ACU71420"/>
        <property type="gene ID" value="Caci_2502"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2502"/>
    <dbReference type="HOGENOM" id="CLU_914286_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="34379" checksum="3826F2149F8CB6EF" modified="2009-10-13" version="1">MRPTPIGMTAGLALSEGVISLSSPALQPIPHLFLRHRPQHTVTCGTPRPRRQHRLKPIKNLIQLHRRLMAVDISTSKQLPPMQQPPIPRKHHPLLPSRPGRQRRIPHIRSLIRGINPQHPQPPRQRPQMNVQQKPQRPPNPLRKTQLPHLHPLPTHRHMPNPHNPPINHQLPNLNQRHPQSLHNMPQTRHAISRNPSPHPTVSRRHKDMQPRVERNTDLHFRHPASMPAPRSRDHWIASRGSRPTPPQHQPHATVQPPGSAANGTPLLLAAQRATMQPPGSAADAHPAASGHSPRHDPTDRHCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXT5</accession>
    <name>C7PXT5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793124.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4532"/>
    <dbReference type="EnsemblBacteria" id="ACU73395">
        <property type="protein sequence ID" value="ACU73395"/>
        <property type="gene ID" value="Caci_4532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4532"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_7_1_11"/>
    <dbReference type="OMA" id="YTHDERE"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="114" mass="12684" checksum="FB9C3520A3BEDF64" modified="2009-10-13" version="1">MEFTCTARQAEQQIVVTVTGEIDLAVYPRLRAEAEIWAGKDADVILDCRQVTFMDSMGVRFLVQVRQMLNDTGHTISLANPSKPVMRVLELAGLRDLFAYTHDEREPATDGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY04</accession>
    <name>C7PY04_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Non-ribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793193.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4602"/>
    <dbReference type="EnsemblBacteria" id="ACU73464">
        <property type="protein sequence ID" value="ACU73464"/>
        <property type="gene ID" value="Caci_4602"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4602"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0663">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002751_1_0_11"/>
    <dbReference type="OMA" id="GVWCESY"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012728">
        <property type="entry name" value="NRPS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02353">
        <property type="entry name" value="NRPS_term_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="879"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="919"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1122"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1149"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="553"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1337" mass="140320" checksum="C3B2F4EF268BC00B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY19</accession>
    <name>C7PY19_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Caffeoyl-CoA O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.104</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.104" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793208.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4618"/>
    <dbReference type="EnsemblBacteria" id="ACU73479">
        <property type="protein sequence ID" value="ACU73479"/>
        <property type="gene ID" value="Caci_4618"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4618"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_5_1_11"/>
    <dbReference type="OMA" id="SVARRYW"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042409">
        <property type="term" value="F:caffeoyl-CoA O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23883" checksum="3FC8F8C74C1029A5" modified="2009-10-13" version="1">MTRGSINLDGALQDYVVDHTTALDEVQRALIARTTELGSPSGMQIGAEQAQLLTLLVRLTNAKHAVEVGTFTGFSAIAIARGLAPGGKLLCCDVSEEWTSIGRAAWQQAGLADRIELRLAPAAETLAALPEQEYIDFAFIDADKPSYWTYYSELVPRMRAGGVIAVDNVLWSGRVVQDEPEEESTRLLKEFNDKVVRDERVDVVMLPVGDGVSLMYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL7</accession>
    <name>C7PYL7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797064.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8516"/>
    <dbReference type="EnsemblBacteria" id="ACU77339">
        <property type="protein sequence ID" value="ACU77339"/>
        <property type="gene ID" value="Caci_8516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8516"/>
    <dbReference type="eggNOG" id="COG1721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026152_4_1_11"/>
    <dbReference type="OMA" id="KLMVRQF"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="3">
        <location>
            <begin position="282"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="497" mass="51391" checksum="0439E967789A6479" modified="2009-10-13" version="1" precursor="true">MSEATPAPHQAPGVPTGTTGSTGTTGVPGQSGQFGPPGTTGTTGTPDPAAAPPDPSAPREPSAAPADSSDTAGAADATAAAASATASPDTAPPERTLRLTSTGTALGLSAIACIVLAYAFGYPAFAALGSAGLVILLCVIPLTARNAPVELNREVYPLRVARGETAVGLLTVRNQSPTWGQRLSATERIGRREIPVRIGQLPPHAAVEVRYELPTTRRGVIDVGPLRWDRTDPLGLVRRRSALPGKAVLHVHPAVHRFPLGTAAQNAQGEQARTDLALEGSITFHTLREYVPGDDLRRIHWRASAHRGELMVRQNIDVTPPKATIVLITDAALYTNPDDFEHAVDVAASAAVGAVRAGQAVSLWTTGGLRLSANGSPEESMLFLDRLAAVNLASIKSSNRNGSGNGEGLAGTLERLEHAERGGVLIVVGGHPQPSEIGTLTRIAGRFGLAALTRIGTTDGPGTGRGAGLTFIDAPTAEEVCHRWERLALASARGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM5</accession>
    <name>C7PYM5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797072.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8524"/>
    <dbReference type="EnsemblBacteria" id="ACU77347">
        <property type="protein sequence ID" value="ACU77347"/>
        <property type="gene ID" value="Caci_8524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8524"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2300728_0_0_11"/>
    <dbReference type="OrthoDB" id="1930308at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010310">
        <property type="entry name" value="T7SS_ESAT-6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06013">
        <property type="entry name" value="WXG100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="11174" checksum="D8EEE60E25165BF8" modified="2009-10-13" version="1">MGNPDFMNIQYATIADFVTELSAVNTAGRQLIEDLTSTLQSNTELWNGVAKLGYNDVHQKWNGQFDRMSAVLAEVQSHGNQTQELYQQIEAQNIALWGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYP7</accession>
    <name>C7PYP7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8549"/>
    <dbReference type="EnsemblBacteria" id="ACU77369">
        <property type="protein sequence ID" value="ACU77369"/>
        <property type="gene ID" value="Caci_8549"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8549"/>
    <dbReference type="eggNOG" id="COG1813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033540_1_0_11"/>
    <dbReference type="OMA" id="ADTHIAE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="44985" checksum="4EA3EB1880F0320C" modified="2009-10-13" version="1">MRGMTETLSIGERVAWYRRRRGMSQEVLAGLVGRTADWLGKVENGRIYLDRLSVIKSLADALDVQLGDLLAEPALLDWAQDVKGRTVSALREALMDYRQLTPLLSGDANGFRPDLEVLKQEVGEAWTAFQDGRFARAAHVVPSVLSLAQAATRSYSGDEQLQAYVLLAMAYQSAAQVLTKIGETELAWIAADRGLTAAQVSGDPIVIGSLFRSVTHCLLSNGRFDAAKQLTADAAGYLQPHVAKASPEFLSIYGTLFLAGSVAAARSDDRATTRTFLAEAEESARRLGEDANHMWTAFGPTNVAIHRVATAMELGDVQLALDQGPQLDTSQMPTERRVRHALEVARAYAARNHTDEALSLILDAEKLAPEQVRYHYISRQLVTSWVRRQHGKPSLALSDLAQRIHVIESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYT7</accession>
    <name>C7PYT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797134.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8590"/>
    <dbReference type="EnsemblBacteria" id="ACU77409">
        <property type="protein sequence ID" value="ACU77409"/>
        <property type="gene ID" value="Caci_8590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8590"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118224_0_0_11"/>
    <dbReference type="OMA" id="PGKFEPH"/>
    <dbReference type="OrthoDB" id="1429052at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="10"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18622" checksum="3CFE9D7FEBE4F197" modified="2009-10-13" version="1">MTRVLYVIPCAAGPAPMVDRLVKLAQAGGWDVWLAPTPSAMDFLDVPSLEALTGHPIRARYRQPGELGKLPMADAVIVAPATYNTINKWAAGIADTHALGLLAELTPSGIPIAVLPFVNASLAANRVFGRSVESLREEGVTVLVGDGGFMPHPAGTGGDRLETFPWELAFEAVGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYT8</accession>
    <name>C7PYT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8591"/>
    <dbReference type="EnsemblBacteria" id="ACU77410">
        <property type="protein sequence ID" value="ACU77410"/>
        <property type="gene ID" value="Caci_8591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8591"/>
    <dbReference type="eggNOG" id="COG3935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_896529_0_0_11"/>
    <dbReference type="OMA" id="IRTRTYF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="30182" checksum="85E27B21809A1973" modified="2009-10-13" version="1">MRVHGTRQTGFFTKVPNATARDHGLSFAARGLLAYLLSLPDGAREDVKTLANKSVEGRGVITRALNELESRGYMTRAKTRDDDGRIHTQVEVFADRGGASRPVVPAPVSPGTGTPGGGKSGIKTEETGVEDSLPPQVPLTDPVADTSASGRAGGELSRALSLLVQVAKDEPRLHLAAGEAGELAALVDRWLARGATPGHVTSALTSGLPPRVHQAAALVRHRLTAKMPPERSKQALGVTWHECAECRVPMRAEGLCGDCSHAGPQAAPTALRKGGRVGFELARAQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYY2</accession>
    <name>C7PYY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA containing CoxE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0601"/>
    <dbReference type="EnsemblBacteria" id="ACU69538">
        <property type="protein sequence ID" value="ACU69538"/>
        <property type="gene ID" value="Caci_0601"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0601"/>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058765_0_0_11"/>
    <dbReference type="OMA" id="VDWLDDI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="225"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="389" mass="42241" checksum="CE1C3933C3BBA534" modified="2009-10-13" version="1">MNAVSQDPETAAALERWRMILGAPASAGMPLSDGNAARDAALDWLYGRDDELARRGVRKGGAADSGGPKGAGGSADSVLTTVDWLDGITRLFPKETVERLTRDAVDRYQIHDIVTDPKVLERVEPSPALLKAVLRTKHLMDPKVLELARKLVSAVIAELMRKLATEVRVSFSGTRLRRPSQVRLARNFDVKRTLRGNLGHYQPEERKLYIEDAHFFTRSRRHVDNWQVILLVDQSGSMVSSVIHSAVTAACLWGLPGVRTHLVAFDTSVVDLTSDVTDPVELLMKVQLGGGTDIAKAVTYAGDLVANPRRTIVALISDLYEGGSETNLLRGARSLIEQGCRFLALCALDEEANPAFNRDLAERLATLGAQVGAMTPGELAAFVAEAVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ24</accession>
    <name>C7PZ24_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4">4.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Beta-thionase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Serine sulfhydrase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_0644</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homocysteine + L-serine = H2O + L,L-cystathionine</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784875.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0644"/>
    <dbReference type="EnsemblBacteria" id="ACU69580">
        <property type="protein sequence ID" value="ACU69580"/>
        <property type="gene ID" value="Caci_0644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0644"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_0_2_11"/>
    <dbReference type="OMA" id="WMADYGF"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004122">
        <property type="term" value="F:cystathionine beta-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005857">
        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="13">
        <location>
            <begin position="336"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU69580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="463" mass="49393" checksum="C5662CB1A46B1F3A" modified="2009-10-13" version="1">MKYAESMVDLVGDTPLVKLNNVTKGLQATVLAKVEYFNPGGSVKDRIALRMIEAAERSGALKPGGTIVEPTSGNTGVGLAIVAQQKGYKCVFVCPDKVSTDKINVLRAYGAEVVVCPYAVAPEHPDSYYNVSDRLVREIPGAWKPDQYSNPENPASHYHSTGPELWQQTDGRITAFVAGVGTGGTISGTGRYLKDVSDGAVKVIGADPEGSVYSGGSGRPYLVEGVGEDFWPTAYDRTVADEIIAVSDKDSFLMTRRLAREEGLLVGGSCGMAVVAALEYAARLGPDDVVVVILPDSGRGYLSKIFNDDWMADYGFLNPGTEEPTVAEVFARKGQGLPDLVHMHPHETVGEAIETLREYGVSQMPVVKEEPPVMAAEVIGSIVERDLLRALFYEKASLEDRLDEHMSPPLPQVGSGEPVSALVTALEKADAAVVLVEGKPQGVVSRQDLLGFLGHEASVSLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ50</accession>
    <name>C7PZ50_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mycothiol S-conjugate amidase</fullName>
            <ecNumber evidence="2">3.5.1.115</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mca</name>
        <name evidence="4" type="ordered locus">Caci_0670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + mycothiol S-conjugate = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + an N-acetyl-L-cysteine-S-conjugate</text>
            <dbReference type="Rhea" id="RHEA:36543"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58718"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="ChEBI" id="CHEBI:59633"/>
            <dbReference type="EC" id="3.5.1.115"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MshB deacetylase family. Mca subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.115" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0670"/>
    <dbReference type="EnsemblBacteria" id="ACU69606">
        <property type="protein sequence ID" value="ACU69606"/>
        <property type="gene ID" value="Caci_0670"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0670"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_2_11"/>
    <dbReference type="OMA" id="PLKLYYN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010126">
        <property type="term" value="P:mycothiol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010127">
        <property type="term" value="P:mycothiol-dependent detoxification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01482">
        <property type="entry name" value="Mca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017811">
        <property type="entry name" value="Mca"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF16">
        <property type="entry name" value="PTHR12993:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03446">
        <property type="entry name" value="mycothiol_Mca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="34998" checksum="0432454FA8E26136" modified="2009-10-13" version="1">MTHELRLMTVHAHPDDESSKGAATSVRYIREGVDVLVVTCTDGSRGDILNPQLKKDPAVQAEIEANLLDVRRKEMDAARAILGVRQEWLGFVDSGLPQGDPLPPLPEGCFAVQDVEAAAEPLVRLMRRQRPQVVVTYNENGGYPHPDHIMTHKVTLAAFEAAGDPEKFPDAGEPWQPLKLYYDVAWSVARIEAEHQEMLDRGLESPYWELLKERETWPQREITTRVPVGEYFETRDAALKAHATQIDPDGPFFRTPNDIRRAVWPTEDFELARSVIDTTLPEDDLFAGVREYEKAREAVSGQGVHEPAGVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ89</accession>
    <name>C7PZ89_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786839.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2629"/>
    <dbReference type="EnsemblBacteria" id="ACU71546">
        <property type="protein sequence ID" value="ACU71546"/>
        <property type="gene ID" value="Caci_2629"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2629"/>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_1_0_11"/>
    <dbReference type="OrthoDB" id="1402673at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="34265" checksum="330AE646D657A0BE" modified="2009-10-13" version="1">MAQAIRRAVIPAAGIGSRLLPLTKAIPKEMLPVGDRPVIEHTVRELVASGITDITIVVSGGKDLIQQHFRPNPALIDQLHAENKHAYAKAVADVVELARAGHITYLDQQGPYGNGTPVLNASRGSGDEPMLVLWPDDVFVAKVPRAQQLIAAYEKTGCPVLALMPMDRENSRRYGVPEVNEDLGDGLLRISSLVEKPEPGSAPSDFAAIGGYVVTAAIIEELEAITRRWEQHQTGEIYLTDAINTYAAKRAVYGQVIAGRWYDTGNPTDYLVAQFASALAHPEYGPVLRDLVENGDEGPSGDSSRERASTAADGLRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZI8</accession>
    <name>C7PZI8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Caci_2731</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2731"/>
    <dbReference type="EnsemblBacteria" id="ACU71645">
        <property type="protein sequence ID" value="ACU71645"/>
        <property type="gene ID" value="Caci_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2731"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036138_3_1_11"/>
    <dbReference type="OMA" id="NFIYYPV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="280"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU71645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="37254" checksum="C455D5404CD35A4F" modified="2009-10-13" version="1">MGVIDTVLNPIIWAVSFVMVLWHRVFGAIFGEGSSVSWVLSILFLTITIRAAMIPLFRKQIKSMQHMQRLQPQLQALQKKYKLDKQKLQQETMKLYKDNGTSPFASCIPILVQLPFFTALYRVLSHAASGRAVGALSQADATNIQHSTFFGAPIPLRFFTTQTYLNTAANGQFAHTSLVNLRIVALVMVVLYAASQFLTQRMMLTKNTNLDNSVPNPMMQSQKIMLYVMPVGMLFFGLSVQIGVVLYLMTTNVWTIGQQFYTLRNSPVPGSQAEKEMIARRKAKEAKKALAAAGNGPVSNTNTVSTADGKAHDDAPVSRQRAQPVRSTRRKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZJ7</accession>
    <name>C7PZJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786947.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2740"/>
    <dbReference type="EnsemblBacteria" id="ACU71654">
        <property type="protein sequence ID" value="ACU71654"/>
        <property type="gene ID" value="Caci_2740"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2740"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="FAILHFI"/>
    <dbReference type="OrthoDB" id="1186918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30644" checksum="80C06C3B35AC7FEC" modified="2009-10-13" version="1">MTPQPGGQPWGNELAPEWIAPGIDSSQAHPARIYDYLIGGKDNFAADREVAEQLILVRPELREVMRANRAFLARAVRFAAESGIRQFLDIGTGIPTAGNTHQIAQAVAPEATVAYVDNDPMVLVHARALMAAEGLGRTTIHLGDLRDPQTILESPEVRAAIDFSQPVGLLLFAILHFISDDDRPAEIVATLRSALAPGSMIAISHATYNPDQLDELARFTDEYNKSASDLFIRRPADVESFFAGFDLVDPGLVPVTDWRPDPDTVPLPPHVGMRGAVGILGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q002</accession>
    <name>C7Q002_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795224.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6649"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM56">
        <property type="family name" value="Carbohydrate-Binding Module Family 56"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75495">
        <property type="protein sequence ID" value="ACU75495"/>
        <property type="gene ID" value="Caci_6649"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6649"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014141_0_0_11"/>
    <dbReference type="OrthoDB" id="1046649at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980495" evidence="1">
        <location>
            <begin position="37"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="49"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="2">
        <location>
            <begin position="502"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="639" mass="66369" checksum="CBCD765271E36241" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q044</accession>
    <name>C7Q044_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795266.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6691"/>
    <dbReference type="EnsemblBacteria" id="ACU75537">
        <property type="protein sequence ID" value="ACU75537"/>
        <property type="gene ID" value="Caci_6691"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6691"/>
    <dbReference type="eggNOG" id="ENOG50314P5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114045_0_0_11"/>
    <dbReference type="OMA" id="GIFNLLW"/>
    <dbReference type="OrthoDB" id="1848269at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981360" evidence="2">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="14963" checksum="72BE72430E71D413" modified="2009-10-13" version="1" precursor="true">MTKFLLSLHVVAAIIAVGPVAVAASMFPRALRQASASEDPDAVTGLRLLHRVCRVYAGIAIAVPVFGFATASNMGVLGSAWLITAITLTAVAAAVLGLWILPAQQAALEEVTAVAASRLAAAAGVFNLLWATVTVLMIVRPGSTTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0K2</accession>
    <name>C7Q0K2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797259.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8720"/>
    <dbReference type="EnsemblBacteria" id="ACU77535">
        <property type="protein sequence ID" value="ACU77535"/>
        <property type="gene ID" value="Caci_8720"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8720"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_3_11"/>
    <dbReference type="OMA" id="ADEGTEC"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="23"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="116"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19764" checksum="A92735CB4DBF935B" modified="2009-10-13" version="1">MTTMVLSAPECHRQSGTIDVADLYATHRLPLTRLAVLLLGDMASAEDAVQEVFVKLWSRPDLLQGVAAPSSYLRTAVVNRARSVQRRRKLEREYAVQDTRDVEPAETTALLPLEHREVMEAVQALPTRQREVLLLRYWADLTETEIARTLGVSRGTVKSTASRGMRAVTIRLRAGNA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0R3</accession>
    <name>MSHB1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 1</fullName>
            <shortName evidence="1">GlcNAc-Ins deacetylase 1</shortName>
            <ecNumber evidence="1">3.5.1.103</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshB1</name>
        <name type="ordered locus">Caci_0756</name>
    </gene>
    <organism>
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate</text>
            <dbReference type="Rhea" id="RHEA:26180"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:52442"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="EC" id="3.5.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MshB deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.103" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784986.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7Q0R3"/>
    <dbReference type="SMR" id="C7Q0R3"/>
    <dbReference type="STRING" id="479433.Caci_0756"/>
    <dbReference type="EnsemblBacteria" id="ACU69691">
        <property type="protein sequence ID" value="ACU69691"/>
        <property type="gene ID" value="Caci_0756"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0756"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_1_11"/>
    <dbReference type="OMA" id="YWNRVPR"/>
    <dbReference type="OrthoDB" id="1380748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035595">
        <property type="term" value="F:N-acetylglucosaminylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01696">
        <property type="entry name" value="MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017810">
        <property type="entry name" value="Mycothiol_biosynthesis_MshB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03445">
        <property type="entry name" value="mycothiol_MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000400173" description="1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 1">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01696"/>
        </source>
    </evidence>
    <sequence length="323" mass="34064" checksum="C79C05F567544DC9" modified="2009-10-13" version="1">MTATTTAQPSGPVPPASPTAARRLLLVHAHPDDEVITTGATMAAYAAEGAHVTLVTCTAGEEGEVLVPELAHLAADREDRLAEIRVVELANAMTALGVADHRFLGGVGCYRDSGMMGTPANDKPHAFWRADLDEAAAHLVKVVREIRPQVLVTYDENGGYGHPDHIQAHRVAMRAAELAADPAFAPEHGAVWDVAKIYWTAMPESVLAEGIQALKEAGDTSGFIAVESVEDLSFGTDDALVTTTIDGTAYMENKREGMRAYPTQISMGQGFFALSNSIGMEFMAHEFYQLVKGAAEGSDTGLEKDLFAGLGIADGTAAGVSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S4</accession>
    <name>C7Q0S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0767"/>
    <dbReference type="EnsemblBacteria" id="ACU69702">
        <property type="protein sequence ID" value="ACU69702"/>
        <property type="gene ID" value="Caci_0767"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0767"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="24459" checksum="A31679ABC10A3760" modified="2009-10-13" version="1">MRADAEDNRRALLEAAREIYVEEGTSVALDKIAKRAGVGIGTLYRRFPDRDALLRGVLVDLFESMSAAVRRAEAEARDAPDGPPAWEAVVRAVAGLGLGPTLPVIFRERFDLIDEPAVAAAMRGAITGVEGVYRRAQEAGLLRADVSFLEVQMLAGMLSQSGPSRPPMIDPETLTDRLVGILLDGLRAGPAHRALPGEPTVFSPLDPDDRAAVERAIAEENERRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1N7</accession>
    <name>C7Q1N7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase PHP domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6743"/>
    <dbReference type="EnsemblBacteria" id="ACU75588">
        <property type="protein sequence ID" value="ACU75588"/>
        <property type="gene ID" value="Caci_6743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6743"/>
    <dbReference type="eggNOG" id="COG0613">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032306_1_0_11"/>
    <dbReference type="OMA" id="DWRYRAR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982699" evidence="1">
        <location>
            <begin position="51"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="POLIIIAc" evidence="2">
        <location>
            <begin position="216"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="541" mass="57592" checksum="62D5DF465DB5CFDD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1W7</accession>
    <name>C7Q1W7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6827</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795396.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6827"/>
    <dbReference type="EnsemblBacteria" id="ACU75668">
        <property type="protein sequence ID" value="ACU75668"/>
        <property type="gene ID" value="Caci_6827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6827"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="LVGMFRM"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="25698" checksum="723792A336949E3A" modified="2009-10-13" version="1">MPELGKGLSGKVAEDLGLAIAGGRHAPGEVLRTDDLAERFGVSRTVVREAVQALQAKRLLRSSPRVGLTVRVVQEWHLYDPDVIRWRLAGSDRRTVLDELTELRAAVEPVAAAAAARRTDRQERTRLLESSARMRAAAAVGDRTAFLEADVDFHCLVLGMCGNPLFAQLAPVTQELLRGRAALKLLPTAPDPADADRHDAVALAVAAGDPERAEVAMRAVVAESLEDIHMRLAARQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q273</accession>
    <name>C7Q273_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797334.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77610">
        <property type="protein sequence ID" value="ACU77610"/>
        <property type="gene ID" value="Caci_8797"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8797"/>
    <dbReference type="HOGENOM" id="CLU_2449189_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="9153" checksum="166EDB17604BA6F4" modified="2009-10-13" version="1" precursor="true">MTVVGTAAASLVLLICLTLAAVSGYIMVAPNSNTEIRPRVVGASLLAIFLAIGAGVVMALLREPVDTYFNAVGVGTFILVGVSVKYGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U0</accession>
    <name>C7Q2U0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787125.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2923"/>
    <dbReference type="EnsemblBacteria" id="ACU71832">
        <property type="protein sequence ID" value="ACU71832"/>
        <property type="gene ID" value="Caci_2923"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2923"/>
    <dbReference type="HOGENOM" id="CLU_2421562_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="9992" checksum="7D621E218481FD9E" modified="2009-10-13" version="1">MVATTPSGKVITCDGCGAAIEEVRENMKHPVLYPHQWAEPNVIYIVCAPLPDGTQPCLDLARLSDELFENTKCRVPGCNGDRCHLARRAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V2</accession>
    <name>C7Q2V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787137.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2935"/>
    <dbReference type="EnsemblBacteria" id="ACU71844">
        <property type="protein sequence ID" value="ACU71844"/>
        <property type="gene ID" value="Caci_2935"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2935"/>
    <dbReference type="HOGENOM" id="CLU_2877526_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="6813" checksum="D141CF41F6EF527A" modified="2009-10-13" version="1">MTSDNRAQAEQLIRPIVGKPKYRGEVYQPEDKSIARAQVHAILALAAAVDRVADALLKAAGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q307</accession>
    <name>C7Q307_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787192.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2990"/>
    <dbReference type="EnsemblBacteria" id="ACU71899">
        <property type="protein sequence ID" value="ACU71899"/>
        <property type="gene ID" value="Caci_2990"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2990"/>
    <dbReference type="eggNOG" id="ENOG50348ZM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853127_0_0_11"/>
    <dbReference type="OMA" id="RHANSPP"/>
    <dbReference type="OrthoDB" id="1891070at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="15022" checksum="A60EBA724678CB41" modified="2009-10-13" version="1">MRREDKFVLSHRPYAVDLSSFRQRFAEHDEWFMVDAVWFRRRSGVTAACAGYLDDGFRRTAPRDVTDFLEKYEDGRYGAKCLARWDGASFWCAGQDPEENARYLELLKPMLENFPAIPPGRDGWWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q386</accession>
    <name>C7Q386_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-xylanase</fullName>
            <ecNumber evidence="4">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="family name" value="Glycoside Hydrolase Family 10"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73822">
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        <property type="gene ID" value="Caci_4962"/>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
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        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="PTHR31490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
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        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="8">
        <location>
            <begin position="53"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="7">
        <location>
            <begin position="670"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="778" mass="78374" checksum="290EE94D90395DA8" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3N3</accession>
    <name>C7Q3N3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="Caci_6968"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OrthoDB" id="1573900at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
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        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="15"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="561" mass="61959" checksum="F2A6BF2FCAA1C1F9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J1</accession>
    <name>C7Q4J1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787253.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3051"/>
    <dbReference type="EnsemblBacteria" id="ACU71960">
        <property type="protein sequence ID" value="ACU71960"/>
        <property type="gene ID" value="Caci_3051"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3051"/>
    <dbReference type="HOGENOM" id="CLU_1851514_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="138" mass="14837" checksum="BE43DA90FBAD2ABA" modified="2009-10-13" version="1">MSLIDEVLDAVTDPESGLFDALYAADTAAAHLKRAGARRNGTLGSEKVYRRAQGEVESASRLASGLDEPFRGLFDVLLGAFHELDAYRFAAAMELQDDYALAELEYAEAVARKALTRVLDADLRHPVAAQAGQLGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4R4</accession>
    <name>C7Q4R4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3124"/>
    <dbReference type="EnsemblBacteria" id="ACU72033">
        <property type="protein sequence ID" value="ACU72033"/>
        <property type="gene ID" value="Caci_3124"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3124"/>
    <dbReference type="HOGENOM" id="CLU_2449187_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="9377" checksum="1601ED0F47060A87" modified="2009-10-13" version="1">MRDRAMRDAMARGAAVPGAAVRMSAGALSVAEGSVRWAQHFSASGHERVLRLRRPPLTNAGMAGAMTEAGTSETGLTETGMTEMTWRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q590</accession>
    <name>C7Q590_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795587.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75859">
        <property type="protein sequence ID" value="ACU75859"/>
        <property type="gene ID" value="Caci_7029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7029"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_3_2_11"/>
    <dbReference type="OMA" id="FKCMQHP"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="11"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="19859" checksum="6EF8F050E7A1A3F5" modified="2009-10-13" version="1">MSTDYASLTGDYTFDVAHSTIGFIARHAMVTKVRGGFNEFEGEIHVDGANPANSSATASVKVASVDTRNEQRNGHLLSGDFFEQDKFPDMTFTSTGVTAKGEDQFVLQGDLTVKDVTKPVEFDVEFLGTTVDPYGNTRIGFEAKTTVSRKDFGMTWNAALETGGVLVSDKIQLELEISAIKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5B8</accession>
    <name>C7Q5B8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="10" type="ordered locus">Caci_7057</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795615.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7057"/>
    <dbReference type="EnsemblBacteria" id="ACU75887">
        <property type="protein sequence ID" value="ACU75887"/>
        <property type="gene ID" value="Caci_7057"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7057"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_7_11"/>
    <dbReference type="OMA" id="DLHCTVT"/>
    <dbReference type="OrthoDB" id="1738789at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="125"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="138"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="155"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="181"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="195"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="125"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="40694" checksum="39F1928B0F06DF93" modified="2009-10-13" version="1">MSTDYYTVLGVRRDATQDEIKKAYRRLARELHPDVNPDPGTQERFKEIGMAYEVLSDPQKRQMYDLGGDPRGAGGAAGGFAGFGFTDIMDAFFGGQTSRGPRSRVRKGNDALIRIEIELSDAAFGSAREITVDTAVICVACSGEGSAPGTHPVTCDMCNGRGEVSQVTRSFLGQVMTSRPCPQCQGFGTVVPSPCPECSGEGRVRTRRKLTVKIPPGVDNGTRIQLAGEGEVGPGGGPAGDLFIEIVELPHPIFQRRGDDLHCTMTLPMTAASLGTKLPLETLDGPAEIDVRPGTQSGHAITLRGRGIQHLRRDGTGGTGRGDLVVHVEVKTPSKLDPEQEELLRRLAKLRGEERPSGEFAPGQQKLFSRLRDAFNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5G5</accession>
    <name>C7Q5G5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_7104</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7104"/>
    <dbReference type="EnsemblBacteria" id="ACU75934">
        <property type="protein sequence ID" value="ACU75934"/>
        <property type="gene ID" value="Caci_7104"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7104"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="LAWHRAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="13">
        <location>
            <begin position="328"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="423"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU75934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="48763" checksum="83E935F40086E73A" modified="2009-10-13" version="1">MSRCAAARQLSTILGVEKRQRGLWLSDGLLVVVYLVLVALVTPALREFHTITDYPNGWYTPLGEQIIPPGGSVTQSTYRANNWQQLEPTIFTMILVPMLRRRPLVFASAVCVGQGLVGSVHASGDTRYELLLAAVACLVSVALAWPRRTSLKAAALILAGAVFSMTAFPPGSSEMMQTHVVVVTLLTLVAWLIGSSIRERRAGAVRQRADAAAQAVANERLRIARELHDMIAHSIGIIAIQAGMGNRVIGTQPAEAQKALHAIEETSRDTLSQLRRTLTALRHGENAETPTDPAPGLADLDKLVASTKHAGVLAIVERIGIPRPLPGEIDLAAYRIVQESVTNVVRHSGARTCRVRIEYQDSAVAIAVSDDGHGVLGSGGTGFGLVGMRERVTLVHGAFEAGPRPGGGFRVSATLPVPGGFETTYGGAKTNADTGTGTGTGTGTDPDPRADTAPDPNPAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5H2</accession>
    <name>C7Q5H2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase beta domain protein region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8970"/>
    <dbReference type="EnsemblBacteria" id="ACU77783">
        <property type="protein sequence ID" value="ACU77783"/>
        <property type="gene ID" value="Caci_8970"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8970"/>
    <dbReference type="eggNOG" id="COG1708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_378424_0_0_11"/>
    <dbReference type="OMA" id="KVRTFCM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="NTP_transf_2" evidence="2">
        <location>
            <begin position="494"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="732" mass="78777" checksum="94D092A0407F0ECC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5K0</accession>
    <name>C7Q5K0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797535.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8998"/>
    <dbReference type="EnsemblBacteria" id="ACU77811">
        <property type="protein sequence ID" value="ACU77811"/>
        <property type="gene ID" value="Caci_8998"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8998"/>
    <dbReference type="HOGENOM" id="CLU_2092394_0_0_11"/>
    <dbReference type="OMA" id="GREKYDI"/>
    <dbReference type="OrthoDB" id="1973445at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="13047" checksum="0075716C47AFCD5B" modified="2009-10-13" version="1">MTNPNLSAARAYILTLANWADLETVTQAIRDRRTVLNANLSPGRTIRLSGLRRCYLNRLTGSIHTIDPTRERADIELDEASTQTLRSKGREKYDIPQEQTRYILRGVPLAACIPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T5</accession>
    <name>C7Q5T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785326.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1106"/>
    <dbReference type="EnsemblBacteria" id="ACU70032">
        <property type="protein sequence ID" value="ACU70032"/>
        <property type="gene ID" value="Caci_1106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1106"/>
    <dbReference type="HOGENOM" id="CLU_093409_3_0_11"/>
    <dbReference type="OrthoDB" id="2070467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="17935" checksum="5FE873A3B448C524" modified="2009-10-13" version="1">MGKKDPLPPGTTIIEGTDGSISFDDQYVTITHTWLSNAGRGEARFPLGAIAGVNVKNGMVLAAVTVVVPGGGIPRKGKDPFTVNGCVKTDAAAFRDLLLAARASVDAVPALEPQAPLIDQAPVVPEASNLVEQLQQLAALRTQGMLSDEEFGIAKAKLLGTSPPEDDVPQPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q607</accession>
    <name>C7Q607_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1179</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785398.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1179"/>
    <dbReference type="EnsemblBacteria" id="ACU70104">
        <property type="protein sequence ID" value="ACU70104"/>
        <property type="gene ID" value="Caci_1179"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1179"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_11"/>
    <dbReference type="OMA" id="GRWPDKL"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="101"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="35893" checksum="C4A71FA863120A8C" modified="2009-10-13" version="1" precursor="true">MRYLLRRVGFFLLTLWAALTLNFFLPHFMPGSPINTLRAQTKGRVSDAQLQQILTSFGYKPHENIVQQYVDYLGNMITGNWGVSLGSSLGTPVSKLIGQSLPWTLGLVGFTTILAFLLGSLIGTIAAWRRGGVVDSVLPSVFVVTSALPYFVVGLFLILFLTVDNTWLPSSGNYDTSIVAGFSPGFVGSVLKFALLPALTLLITSIGGWVLTMRNNMITTLAEDYIRMGRAKGLSDRKVMMNYAARNAFLPNLSGFAMSIGFVLTGAILVEKIFNYPGLGYQLYNAVNSIDYPMMQALFMLFTVAVLGALLICDLVTVWLDPRTRAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q654</accession>
    <name>C7Q654_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BAAT/Acyl-CoA thioester hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3151"/>
    <dbReference type="EnsemblBacteria" id="ACU72060">
        <property type="protein sequence ID" value="ACU72060"/>
        <property type="gene ID" value="Caci_3151"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3151"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029849_0_0_11"/>
    <dbReference type="OMA" id="WFGGPGQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014940">
        <property type="entry name" value="BAAT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08840">
        <property type="entry name" value="BAAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAAT_C" evidence="1">
        <location>
            <begin position="71"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30838" checksum="AFE01D152E7E2F82" modified="2009-10-13" version="1">MVTVEHEMSEPWEAVLCEPEGGSEFGVLVLAGSSGRILRDRARILAEEGLSALAIRWFGGPGQREGIWELPLETFTAAIDLLQERGAQRIGIVGNSKGAEAAMLTAVRDPRVDVVVALAPTSLVWGNVGVGPDGERTPYRSSWTWQGEPLPFVPYDDSWWDTAPARPRAVRGLYELSEKTFADRLAAAGIPVEQAQAELLLVAGGEDRMWPAMTYALRLAERRRVARRTVRLISHGDAGHRVLFPGEPANAVSEEFDYGGSEDSERRLGAQAWPSVLAALRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6C8</accession>
    <name>C7Q6C8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787427.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3227"/>
    <dbReference type="EnsemblBacteria" id="ACU72134">
        <property type="protein sequence ID" value="ACU72134"/>
        <property type="gene ID" value="Caci_3227"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3227"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="FTEYVAL"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="11"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="32512" checksum="188C6E5C75C0B154" modified="2009-10-13" version="1">MRAIAVPEIGGTPGLTELPVPGPGASPGPEEVLVRLSAASINPIDLDIAQGRLPLPTTQPLVLGVDGAGRVVEVGESVHGFVVGDLVHGQFLDAPLGRGTFAEYAVLSGSPSHGALLRTPDGLSAEVAAALPTAGMTALGVVELVELRAGQSILIVGATGGVGVFAVQLAAARGAEVIATARSEAGAWIRGLGASQTIDYGVEDVSELVRGSHPDGVDVLLDLTRDQARFTAYADLVRDGGSAVSATFTASPELLASERISVTNFMMRDKPDLLARITDEVASGRVTVPIERTVTLDEVPEALARNAGGGARGKTVVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6E0</accession>
    <name>C7Q6E0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3239"/>
    <dbReference type="EnsemblBacteria" id="ACU72146">
        <property type="protein sequence ID" value="ACU72146"/>
        <property type="gene ID" value="Caci_3239"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3239"/>
    <dbReference type="HOGENOM" id="CLU_1871679_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14948" checksum="F281097071E40EF7" modified="2009-10-13" version="1">MPTASVREPQRNVREPLRSVNVREPLRAANVRDSLKLNVRDSLKRNVRDVLKHNVRDIQCNLRDIKRNVRDINAVNSGFAEPEADKVVSGKLIASADADKVISAKLIASMDADKVISGKLIASADADKVISNKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q741</accession>
    <name>C7Q741_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795782.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7225"/>
    <dbReference type="EnsemblBacteria" id="ACU76054">
        <property type="protein sequence ID" value="ACU76054"/>
        <property type="gene ID" value="Caci_7225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7225"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_4_11"/>
    <dbReference type="OMA" id="HARVENR"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16407" checksum="F6A0187A9A50F353" modified="2009-10-13" version="1">MPSPAKSAKSAKSSDAHTWSRLLILHAHVESRLATVLQRRHGLGLSEYRALSFLDQADNSELRMTELADLLGLNQSSVTRLVGRLNAAEFTYRDLCPDDKRGAYTVLTDAGRERYREARATYEATLSAALDELAAADPAHAAVVEAARAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q746</accession>
    <name>C7Q746_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl transferase family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785428.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1209"/>
    <dbReference type="EnsemblBacteria" id="ACU70134">
        <property type="protein sequence ID" value="ACU70134"/>
        <property type="gene ID" value="Caci_1209"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1209"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_2_2_11"/>
    <dbReference type="OMA" id="MCLGFLP"/>
    <dbReference type="OrthoDB" id="728505at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="449" mass="47207" checksum="EEC052B9D15A5C8C" modified="2009-10-13" version="1" precursor="true">MREYLLAMTVALAVTLLLGGPIRALAIRLGLVPVIRERDVHVTPTPRVGGLAMFIGLAAALTAAEHFPMLERDVYGESNTIQALLWGGFLVVLLGMVDDKFELDPLTKFAGQIFAASVMVVKGIQISWLVIPGIGIVAVDPTLSIVLSVFLVLALMNAVNFVDGIDGLAAGVSGIAALSSFAYCYRLAISYKLTGATAPALIAIVTVGICLGFLAHNWDPARMFMGDTGSMLLGMLLAATSIAIMGGIDPYQLGAGVSQTTSVHKLVPAYLPLIMPVSVTLLPIADMVMAVVRRTKAGLSPLAPDKGHLHHRMLQIGHSKRRAVLIMYFWSALVAFVTVLFAVTPSRQPIVYGAIAMTLVGLLMLLGPRLGDHRERLRNKALRVGSSTTARHRANTGGAAGAAGTAAPEGALSQGSTVEAAIPAIAASTENGVDRADPDGGMRHRTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q749</accession>
    <name>C7Q749_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ordered locus">Caci_1212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1212"/>
    <dbReference type="EnsemblBacteria" id="ACU70137">
        <property type="protein sequence ID" value="ACU70137"/>
        <property type="gene ID" value="Caci_1212"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1212"/>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041018_0_1_11"/>
    <dbReference type="OMA" id="FTHAVRL"/>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU70137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="31005" checksum="AC45096F474AED77" modified="2009-10-13" version="1">MSLSLASGTVLAADSGTGCGSGTPHLFGNNGGFSCVSPSSEDFDFASRPAFHIFGYGVTKPTLIVALIVVLMITFFWVAFNKPKMVPRGVQNVGEVAYLFVRDRIARDSMGKQGDKYVPFLFTLFFFVWLMNVMSFVPVVQFPVSSVYAFPLALAIMVWLTYMYAGFKRHGLGYFRVLGVPSGVPIGILVILTPIELLSNIFIRPFTLGIRLFANMFAGHLLLATFSAGAWYMFSVKGIVFSGASFTMAIVMTGFELFIQALQAYIFVMLTASYLQGALEEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E0</accession>
    <name>C7Q7E0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785522.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1303"/>
    <dbReference type="EnsemblBacteria" id="ACU70228">
        <property type="protein sequence ID" value="ACU70228"/>
        <property type="gene ID" value="Caci_1303"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1303"/>
    <dbReference type="eggNOG" id="COG1720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013458_2_1_11"/>
    <dbReference type="OMA" id="QIQYFAR"/>
    <dbReference type="OrthoDB" id="1535774at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="17146" checksum="BF985363C0330884" modified="2009-10-13" version="1">MTSFEVTPIGTVRNDRTDVQNSDNWGAVRSTIVVDERFGEACLQGLEGFSHVEVLFVFDQLAEREDYREPAPYRGRADLPPVGIFAGRGPRRPNRIGVTSCAVESVRGRELTVVGLDAVSGTPVLDLKPVMAEFQAVDVRQPAWVSAMMADYFRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7P7</accession>
    <name>C7Q7P7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3333"/>
    <dbReference type="EnsemblBacteria" id="ACU72240">
        <property type="protein sequence ID" value="ACU72240"/>
        <property type="gene ID" value="Caci_3333"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3333"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_2_11"/>
    <dbReference type="OMA" id="DPPRTEM"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="27845" checksum="BB1F7CA2623C8115" modified="2009-10-13" version="1">MTQEPRYRRIAEELRHAITEHAYGPGGKLPSEGALAGQYEVSRGTIRQALMLLRQDGLVTSRRGTRRVVLDDAPVQDFAQMQSFARWARSIGETPEGRVVGQGWHPADPNEQRHLRIDADARVLHVMRLRLLSGRPAMLERTVYPELAGTIVENLASDTVSVTEFLESAGIFVADAEHTIDLVLAAPEDAELLGCAPGDPLLRERRRSTDPAGVPLEWSEDRYVPGSVAFVVHNSLASTPMTRQHMVPGNSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q849</accession>
    <name>C7Q849_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793945.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5357"/>
    <dbReference type="EnsemblBacteria" id="ACU74216">
        <property type="protein sequence ID" value="ACU74216"/>
        <property type="gene ID" value="Caci_5357"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5357"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_5_1_11"/>
    <dbReference type="OMA" id="HWMNPRL"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="464" mass="47297" checksum="1E5389B40188886B" modified="2009-10-13" version="1">MADATEPRGGRETRGAAVDGRAAVGSGTAIGGGAVGGAAIGRDSAIGSGAVGGAAAVGSAAVSGSAVSGAAVGDGAAVSGAAAPLLAGIKVLNLASVGPAARAGRWLADYGAAVVNVGAVPSRGKEPIQITPVFHAYSGHRGMRRILLDLKAERGREAFLRMAERADVVIESFRPGVTDRLGVGYEAVRGRNAKIVYCSTTGFGQSGPHAQWAGHDLDYLAVGGYLAVGEPGVRGNPALPGATLADSAGGGMHAVIAILAALVKGEGAYLDVSVADGVLSLMSLAVDEYLATGSEPGYQHSMTSGRYACYGTYAAGDGRWLAVAAIEPRFWANFCRLLGLEKWAGHQTDDVVQDQIRADIATSLAAKDRDAWVAILSGADTCVAPVLSVAELTEDAQYRSRDAFVAAQHPEHGELRQSAPLLAGMLRSDQPYQLPSGTHSAQLLLEAGFTEAEIKELLEEGTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8P0</accession>
    <name>C7Q8P0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785599.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1382"/>
    <dbReference type="EnsemblBacteria" id="ACU70305">
        <property type="protein sequence ID" value="ACU70305"/>
        <property type="gene ID" value="Caci_1382"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1382"/>
    <dbReference type="HOGENOM" id="CLU_727022_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="380" mass="37112" checksum="9B45F23AD40D9DD3" modified="2009-10-13" version="1">MSQDDQRNQPNEDSARDAAAAGAAESAGTSAPGATGPAQPAATTSGQDPVQPAASDPGAPDPVHPDITTTSGAADPAHPAAATTSGGATVSTAAAASASAPASPSARQTSARREFHEAGEGAARYAVSVGEAPRSGSEQSWSAEPNPGYQRDPAINYPTKRVVAGTLIGALLLAGGVVYAARLLTNRSGNGNGAAPWTAAYSQDGAVVGGISAQNNGSAPEIELPAHLTFGTSGSVSSGVFTAAIASCRTATAISVPVTSETGTAAAIGTWSSQAAAAAQKLRADAATLESALNLGHADAVASAANTLCLGYPTIAAVPPMPDAEGSHAWASAVSSFANAATQALQGVSGNPDATSAAFDALRQGNDQLTAMSARIDSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8U4</accession>
    <name>C7Q8U4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785653.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1436"/>
    <dbReference type="EnsemblBacteria" id="ACU70359">
        <property type="protein sequence ID" value="ACU70359"/>
        <property type="gene ID" value="Caci_1436"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1436"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_1_1_11"/>
    <dbReference type="OMA" id="PFQIMAN"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="12"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="33804" checksum="375FE6E70F538A55" modified="2009-10-13" version="1" precursor="true">MTSPVSVNRTTAGVLFGVTSSVAFGAGGPFAKALIAAGFSPLQAVWIRLVGTVVVLVALCLVLRRPGQLATMARHKWPIVTYGLVAVAACQALYFVAASRLPVGIAILLEFTGPVLVVAWEKLVRHAHVSRESAIGVGVAMLGLAVVVQIWSGVHLDAIGLMAGLGAAAGNATYFLLIDRLAGSVDPLTLTTGGMIVGMVVLVPLAAPWSAPWHILGQSVPMGSHHLPGWTLAAFIVLISTILSYLSGAAAIQRLNAPVAAGLAYVEPASATIVAWAALGERLSLTQIAGGVIVLAGAFLAQRGIGHTTGADPDSGRSILGTTVTTEALIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9A4</accession>
    <name>C7Q9A4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5391"/>
    <dbReference type="EnsemblBacteria" id="ACU74250">
        <property type="protein sequence ID" value="ACU74250"/>
        <property type="gene ID" value="Caci_5391"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5391"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="QATEYIA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="260"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="320"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="542" mass="58360" checksum="072A0B1F68FA9BE1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9D2</accession>
    <name>C7Q9D2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794007.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5419"/>
    <dbReference type="EnsemblBacteria" id="ACU74278">
        <property type="protein sequence ID" value="ACU74278"/>
        <property type="gene ID" value="Caci_5419"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5419"/>
    <dbReference type="eggNOG" id="ENOG502ZXGF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2583273_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="7506" checksum="A92C53A8E5D42615" modified="2009-10-13" version="1">MSEQTTGSSTAGGFQGDLTEAFNPAPGIGCCGSPAANTGVQTATPVAGPCCGTAEEAKAEGACCGSAAKTEAVAASTGCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9G6</accession>
    <name>C7Q9G6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5453"/>
    <dbReference type="EnsemblBacteria" id="ACU74312">
        <property type="protein sequence ID" value="ACU74312"/>
        <property type="gene ID" value="Caci_5453"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5453"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_11"/>
    <dbReference type="OMA" id="EVSGIEC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="15"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35762" checksum="AF3891F7E00CAF37" modified="2009-10-13" version="1">MISVMMRAIVLSGPGPVENLELKELPLPDQRDGWVRIRVEAFGLNRSEYHTRLGFAEGVDFPRVLGIEAAGTVDWAPESSGLVPGQKVVTMMGGMGRIYDGGYAEYTSVPQEQVIPFESELPWDVLGSVPEMLQTAYGSLSVGLDLQPLQTLLIRGGTSSIGMAAAALAKQIGATVLATTRRADRLDTLRERGVDHPLLDDGDVAKRVHAIFPDGVDAALELVGTPSLPDTLAATRVHGTVCMTGMLSDQWTVENFYPIGYIPSGVRLTGYGGEASDLPREVLQRTLDDIASGTLQWPVSRVYDGLEQVRQAHADMEANAAAGKLVVRVRPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA27</accession>
    <name>C7QA27_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1504"/>
    <dbReference type="EnsemblBacteria" id="ACU70425">
        <property type="protein sequence ID" value="ACU70425"/>
        <property type="gene ID" value="Caci_1504"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1504"/>
    <dbReference type="eggNOG" id="ENOG503315W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131550_1_0_11"/>
    <dbReference type="OMA" id="VWQKSRH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="41"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="11343" checksum="163C3288C8BB171B" modified="2009-10-13" version="1">MLIHAQMHVQWINPSHRTCKGKNEMSEFEPYNGMPATEVAAAWRKSSYSNSQGNCVEFAGMGDGSVAVRNSRDPHGPALLYTRAEIEAMINGIKDGEFDDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA74</accession>
    <name>C7QA74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1551"/>
    <dbReference type="EnsemblBacteria" id="ACU70472">
        <property type="protein sequence ID" value="ACU70472"/>
        <property type="gene ID" value="Caci_1551"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1551"/>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_0_11"/>
    <dbReference type="OMA" id="REGLNQH"/>
    <dbReference type="OrthoDB" id="478143at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="458" mass="50659" checksum="ABD7AF3C272DC306" modified="2009-10-13" version="1">MSTDSLDKSAYDHLWMHFTRMSGYRDNPVPTIVRGEGARIFDSNGKRYLDGLAGLFVVQAGHGRVELAEAAYKQAQELAFFPLWSYAHPQAIELADRLAHYAPGDLNKVFFTTGGGEAVETAWKLAKQYFKLVGQPMKHKVISRNIAYHGTPHGALSITGIPDAKKYFEPLVPGAHKVPNTNYYRADEITGVPGMSEEEFGIWCANQVENMILTEGADTVAAVFVEPVQNSGGCFPPPPGYFRRLREICDQYDVLMVSDEVICAFGRLGTMFACDKFDYVPDIITCAKGMTSGYSPIGATIVSDRVAAPFYEGTNYFPHGYTFGGHPVSSAVALANLELFEREGLNQHVLDHEGAFRSTLEKLTDLPIVGDVRGDGFFYGIELVKDKATKETFDDDESERLLRGFLSKALFDAGLYCRADDRGDPVVQLAPPLIVGQSEFDEIEQTLRSVLTEAWTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAA3</accession>
    <name>C7QAA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785795.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1580"/>
    <dbReference type="EnsemblBacteria" id="ACU70501">
        <property type="protein sequence ID" value="ACU70501"/>
        <property type="gene ID" value="Caci_1580"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1580"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047644_0_0_11"/>
    <dbReference type="OMA" id="QWHIVAM"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="26"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="44505" checksum="2B9DE6A4CBAA3E83" modified="2009-10-13" version="1">MTAADSRISPDLVAVAGRAAAVQRRTVRVLIGSQILGGIGSSTGFSLSTLLAKEITGNAGLAGLTGTFSSLGAACAAIPLSRIMAARGRRPGLVLGYGAAIVGTLVIVLAARLHAYPLLLGGMALFGSASAVNLQARYAGTDLAPAERRGRSLSMVIWAVTVGSILGPNLGHPAEGTARALGLPPLAGAFLWSGFALCGAALVLGLLLRPDPLLVARELRGEDAAAPERLTLRESFAVIGASPYAVLAIAVVAVSHTVMVSVMSMTPVHMNSDGMSVTVIGLVLSVHITGMYAFSPLVGAAVDRIGRIPVLGAGLVVLSAACLVVGAAPMGSRSYLMAGLLLLGIGWSCGVVAGSTLLTESTPDRVRPSVQGASDFVMQGSSAGGAALAGLVVGTLGYSWLAGLAVALLAPVAVLVVVTAVRRPGVAANIPGRSVQEDVAPQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAH8</accession>
    <name>C7QAH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3572"/>
    <dbReference type="EnsemblBacteria" id="ACU72477">
        <property type="protein sequence ID" value="ACU72477"/>
        <property type="gene ID" value="Caci_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3572"/>
    <dbReference type="HOGENOM" id="CLU_3306712_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981506" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="39" mass="3675" checksum="C8B64CEF13C882C7" modified="2009-10-13" version="1" precursor="true">MSRKPLAAVLAGTALFVLGSAGAASAHVTIGPDATTPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAI2</accession>
    <name>C7QAI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3576"/>
    <dbReference type="EnsemblBacteria" id="ACU72481">
        <property type="protein sequence ID" value="ACU72481"/>
        <property type="gene ID" value="Caci_3576"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3576"/>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084115_2_0_11"/>
    <dbReference type="OMA" id="NKDSTTH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982958" evidence="2">
        <location>
            <begin position="36"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="3">
        <location>
            <begin position="76"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="15169" checksum="0B252C7606E0CA15" modified="2009-10-13" version="1" precursor="true">MLRFSGKTAAATLLAAATALTLTACSSSSSHPAAAPSGTSTSSSPSMSTSMSSGTSASTSPGAGTGSTGVPVGAPQIVISNFTFSPSTLSVSAGQKVAVINNDSVAHTVTASTGNAFDTGDVNPGQTVTFTAPATAGTYAYTCTIHPFMHGTLTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAJ6</accession>
    <name>C7QAJ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-N-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792224.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3590"/>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72495">
        <property type="protein sequence ID" value="ACU72495"/>
        <property type="gene ID" value="Caci_3590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3590"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017810_1_1_11"/>
    <dbReference type="OMA" id="FRWEDSV"/>
    <dbReference type="OrthoDB" id="620389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-AF_C" evidence="3">
        <location>
            <begin position="291"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="55545" checksum="A19CC4731B528E94" modified="2009-10-13" version="1">MPRAHIVLDKQAVVAPVRRRTFGSFVEHLGRCVYTGIYEPDHPSANDDGFRMDVVDLVRELGSTTIRYPGGNFVSGFRWEDSVGPRGKRPVRRDLAWHSLESNQVGLDEFAAWLKLTGSELMLAVNVATRGILPALDLLEYANHPSGTALSDLRIANGAPDPHNVRMWCLGNEMDGPWQTGFMSAEDYGKIAARTAAAMKMADKDLELVVCGSSGSGMPTFGDWERTVLEHSYDHVDYVSCHAYYQELDGDLGSFLASALDMEYFIDTVIATADHVGYKKRSSKKIDISFDEWNVWYLKEHQESEKSKEADNEWRHAPRQLEDVYTVADAVVVGNLLMTLLKRGDRVTSASLAQLVNVIAPIMTEPGGPAWRQTTFHPFSITSRLAAGEVIRPVIDAPTYTTARYGEASVVDAVATVDGDRAAVFLVNRDLTQSAQVTVDVRSLGLSRVLEALTLADSDVYAKNTLAEPLRVVPRANTGATLSDGVLTVELPPVSWSAIALGQSAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAM2</accession>
    <name>C7QAM2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavoprotein WrbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792250.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3618"/>
    <dbReference type="EnsemblBacteria" id="ACU72521">
        <property type="protein sequence ID" value="ACU72521"/>
        <property type="gene ID" value="Caci_3618"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3618"/>
    <dbReference type="eggNOG" id="COG0655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_0_2_11"/>
    <dbReference type="OMA" id="SRFGMMA"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="21892" checksum="21E9ADFED5D8AC33" modified="2009-10-13" version="1">METPVNVAVIYYSATGSVFQLAKAAATEAEKSGAEVRLRKVRELAPDEAIATNQGWSEHIATTQHIAEAVLDDLEWADVILLGSPTRFGLPAAQLKQFIDTTGGLWGQGRLVNKVGSSFTSTATAHGGQESTILAMNNTFYHWGCVIVPPGYADPIQFQAGNPYGASHISNNGAIPPGEVELAAVAFQTRRAVQIAETLRRGRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBC0</accession>
    <name>C7QBC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7587"/>
    <dbReference type="EnsemblBacteria" id="ACU76411">
        <property type="protein sequence ID" value="ACU76411"/>
        <property type="gene ID" value="Caci_7587"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7587"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043035_2_0_11"/>
    <dbReference type="OMA" id="FEYWAHE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="43904" checksum="EB43AC8A95E747B8" modified="2009-10-13" version="1">MTDVTSVPVPHTELSAAEARRLALHAQRLIGVPDRRGGVAGLLQHLGAVQLDTISVLARSHELVPYARLGAIGREAIEHAYWNHEAHGASTFEYWAHAACILPVQDWPTFAYRRAAFRARANGGWGMPTTGEAEAMVLGKLRDEGPCMTSDFGGARKSAEWWDWSESKVAVEKMLATGDVVCVERRGWRRVYDLPERALPKAVLDAPEPTREESHVRLLAQAGRRLGVGTIGDLADYYRLKIPDAKPLMERTGLIPVTVRGWSHPAWADPAALELLAAGGPRGRHRTTLLSPFDSLIWERDRMERIFGMVHRIEAYTPAAKRVHGYFAMPLLAGGKLLGRVDPKREGKTLVARKVSLDTANAVQPMADALREAALWVGCDAVAVEQVTPPTAAGALRIALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF5</accession>
    <name>C7QCF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III Xth</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5745"/>
    <dbReference type="EnsemblBacteria" id="ACU74603">
        <property type="protein sequence ID" value="ACU74603"/>
        <property type="gene ID" value="Caci_5745"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5745"/>
    <dbReference type="eggNOG" id="COG0708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027539_3_0_11"/>
    <dbReference type="OMA" id="WWSYRGR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="31873" checksum="838A466B2407D067" modified="2009-10-13" version="1">MRVLTVSTVNVNGIRAAAAKGFTEWLKATPADVVCLQEVRAEPDQFPADLRAPEGWHTLVAPAAAKGRAGVALFSRVAPTTTRIGFGTPEFDTAGRYAEMHLPTLTIASLYLPTGEVGTERQAEKERFMAGFHAHLSALSTEAAQTGRAILICGDWNIAHDKADIKNWRANQKSSGFLPEERQWLTSVLTEAGYADVVRNLHPGVDGPYSWWSFRGKAFDNDTGWRIDYQMASANLAALATSAKVERAATYAERWSDHAPVTCAYDWDLAAVPAPRSPISIVGTELLEDSAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM7</accession>
    <name>C7QCM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type phosphate transport system periplasmic component-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796215.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7666"/>
    <dbReference type="EnsemblBacteria" id="ACU76490">
        <property type="protein sequence ID" value="ACU76490"/>
        <property type="gene ID" value="Caci_7666"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7666"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_863110_0_0_11"/>
    <dbReference type="OMA" id="SWIAQAN"/>
    <dbReference type="OrthoDB" id="1458261at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981545" evidence="1">
        <location>
            <begin position="32"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="348" mass="35832" checksum="B3D74832A6E010D9" modified="2009-10-13" version="1" precursor="true">MRSVTRKFAMASAIAAASLGVAIASLGPAAADPPSGTTPASTDIVSTGSDTIQAFDNGLSAAYNATSPASKYYSWDATPAGSIVPKTGAATIARPNGSGAGITALNSNTSATVDIARSSRGPNTGSTDWFIPFATDAVGWSAYTGGHAPSNLTSAELKGIYNCTYTKWNALPTDPTTSTDTIQVFLPQTSSGTRAFFLAALGITATSEPCWQTVTPEENEGTDAAFAGNTDAIYPYSLSHYVGQVYDGKGSGSDEPGALDALRSLDSVPQIDTANKVWNSNLSLTYTRNVYHVVRQADWANATEGPRLKALLNRSAAGGWLCANGSTLISSYGFHALASGCGTLQPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS2</accession>
    <name>C7QCS2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ordered locus">Caci_7711</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796260.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7711"/>
    <dbReference type="EnsemblBacteria" id="ACU76535">
        <property type="protein sequence ID" value="ACU76535"/>
        <property type="gene ID" value="Caci_7711"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7711"/>
    <dbReference type="eggNOG" id="ENOG5032RSG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_6_2_11"/>
    <dbReference type="OMA" id="DTCLKWA"/>
    <dbReference type="OrthoDB" id="1944871at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="9418" checksum="71EA9465AC915FE8" modified="2009-10-13" version="1">MDWRHRAACRDEDPELFFPIGNTGPALLQIEDAKAVCRRCDVVDQCLQWALESGQDAGVWGGMSEDERRALKRRAARARSRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD41</accession>
    <name>C7QD41_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Caci_1830</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786045.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1830"/>
    <dbReference type="EnsemblBacteria" id="ACU70751">
        <property type="protein sequence ID" value="ACU70751"/>
        <property type="gene ID" value="Caci_1830"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1830"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_3_11"/>
    <dbReference type="OMA" id="HMVGDRM"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="7"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="345"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU70751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="48725" checksum="C11926EE19080825" modified="2009-10-13" version="1">MAGDNQFDLVILGGGSGGYACAFRAADLGMSVALIEKAEVGGTCLHRGCIPTKALLHAGEIADNTREAAQFGVAATFHGIDMAAVNSYKDGVVGQLYKGLQGIVKARKIEFIAGEGKLVSANTVQVSTNNGSGGQNVTGSNVVLATGSVPKSLPGLEIDGNRVISSDHALKLDYVPASAIILGGGVIGCEFASVWKSFGTDVTIIEGLPHLVPLEDENSSKLLERAFRRRGIKYELGNFFSGVEYTENGVRASIANGKTVEADLMLVAVGRGPVSAGLGYEEAGVAMDRGYVKVDQYCRTSVPGVYAVGDLIPTLQLAHVGFAEGILVAEHIAGLNPAPIDYDGVPRVTYSHPEVASVGLTEAQAKGKHGEDAVKTFNYDLAGNGKSKILKTSGQVKVVQQVDGPVLGIHMVGDRMGELVGEAQLIFNWEALPQEVAQLVHAHPTQTEAMGEAMMALAGKPLHVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDJ3</accession>
    <name>C7QDJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5759"/>
    <dbReference type="EnsemblBacteria" id="ACU74617">
        <property type="protein sequence ID" value="ACU74617"/>
        <property type="gene ID" value="Caci_5759"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5759"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="LTMTNGQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="108"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="36426" checksum="96F2AB8BDB606B4F" modified="2009-10-13" version="1">MPTAPTTLADSTLADAVTKSMNTAGAVIGFLAVLAALFAVAGRARGRWSRRTALAVFLVPALALLTVGLLIPAVRTIYLSLHGADGTRSVGMRNYVWAFTNDAIRQVLLNTVVWIVVAPIAATALGLGLAVLVDRMRHEALYKALIFLPMAVSFVGASIIWKFVYEYRAPGEHQIGLLSQVFMTLGWKNPPNWLLSHPLNNFLLMVILVWVQTGFAMVVLSAAIKAVPTDIVEAAKLDGARGVRVFVFVTLPMIRNTMIVVLTTIMITTLKVFDIVRTMTGGNFGTQVLANEMYSQSFVQFNTGRGSALAVILFLAVLPLVGYNIVRLRKERVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDS8</accession>
    <name>C7QDS8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5844"/>
    <dbReference type="EnsemblBacteria" id="ACU74702">
        <property type="protein sequence ID" value="ACU74702"/>
        <property type="gene ID" value="Caci_5844"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5844"/>
    <dbReference type="eggNOG" id="ENOG502ZSEC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1934253_0_0_11"/>
    <dbReference type="OrthoDB" id="2197647at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13727" checksum="B71C37E24E10F7A9" modified="2009-10-13" version="1">MTPEFLTTVAESAGRVADTLQSLPFRADRPYDPRPVATVAAEELAVLWGVVAALGRPLVVDTPTKAEPLGVDLAGLMSFLQLVAVLYHGLETVPPVLTVSAGRNLSATHLIARRVRDRARKEAIGSSAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC5</accession>
    <name>C7QEC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase dimerisation and phosphoacceptor region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786110.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1896"/>
    <dbReference type="EnsemblBacteria" id="ACU70816">
        <property type="protein sequence ID" value="ACU70816"/>
        <property type="gene ID" value="Caci_1896"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1896"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_8_11"/>
    <dbReference type="OMA" id="CTIEIAR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="186"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="41432" checksum="171202875A2BB5C9" modified="2009-10-13" version="1">MTPVIHGDWSDSDADIPALARMRRYTTGTVVVLVAGYVLLVAGGSRSLWSLVATLGIGALVCWQCLYWERGAPKALAAVTVSASYVLLWLILGTHGSPIGGVGFALSAGLVVTTPPFTKWPWTALAIGLGVLPALVFGAERGNVIGAGVMMASSVALFRVNRFGFGLFLDVDQARRATAELAVMRERYRFAADLHDIQGQALHVSRLKLRLADKLLAEDPAVARTHLREAEQLIADAIAETRRLAYGQRTLTFAGELANSESLIRAAGISFEVAGAAPVGHRLDELFGLVVREATTNLLRHAQAEHVAITLRPDSVRIVNDGAEEATRTLSGLARLGERFAAAGGVLVTSQEGRTFTTWARDAASDAAPDASAAPNASEAPKVSNPRGPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEJ0</accession>
    <name>C7QEJ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="1">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GlcN6P deaminase</fullName>
            <shortName evidence="1">GNPDA</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nagB</name>
        <name evidence="3" type="ordered locus">Caci_1961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786174.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1961"/>
    <dbReference type="EnsemblBacteria" id="ACU70881">
        <property type="protein sequence ID" value="ACU70881"/>
        <property type="gene ID" value="Caci_1961"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1961"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049611_1_1_11"/>
    <dbReference type="OMA" id="FNEPCSS"/>
    <dbReference type="OrthoDB" id="1828393at2"/>
    <dbReference type="UniPathway" id="UPA00629">
        <property type="reaction ID" value="UER00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="2">
        <location>
            <begin position="10"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for enolization step" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for ring-opening step" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="For ring-opening step" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Part of the allosteric site" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="26950" checksum="486B72EF6D5CD560" modified="2009-10-13" version="1">MEVVIVADAAAQGELVASAVADLIARKPEALFGVATGSTPLPVYQALAAKVAAGQVDVGRLKVCQLDEYVGLPAGHPESYREVLKREVLAPLGIGDSAFLGPDGGAEDLPGACAAYEQQLADAGGVDLQLLGIGTDGHIGFNEPVSSLASRTRIKTLTERTRVDNARFFNGLDEVPRHVITQGIGTILQARHLVLLATGAGKAEAVAATVEGPVSSMVPASALQLHPHATVVVDEAAAQQLKLSDYYKATFASKPAWQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET5</accession>
    <name>C7QET5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792584.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3979"/>
    <dbReference type="EnsemblBacteria" id="ACU72855">
        <property type="protein sequence ID" value="ACU72855"/>
        <property type="gene ID" value="Caci_3979"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3979"/>
    <dbReference type="eggNOG" id="ENOG502ZCH5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093112_0_0_11"/>
    <dbReference type="OMA" id="QHIHIVT"/>
    <dbReference type="OrthoDB" id="1448496at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983155" evidence="2">
        <location>
            <begin position="35"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="26222" checksum="3517E018609C349E" modified="2009-10-13" version="1" precursor="true">MTHAKRTTRIMALAAAPAALLAFPLAFTASTASAQSSGSATYMATLNPLNHAGGSGSLMLQLTGDKAVITENVHGLATTFMGAAYPHVQHIHIGAAGACPSGTSADKNGDGVISTTEGAPFYGGIGTTLSVSGDTSPAAGTDVKIAPSGGSFDYSRTITLDSATVSSIESGKAVIVVHGLDPTTLSAQAQAEPSDLVPSLPLAATSPALCGPLQVSQMAAVPGGGVNTGGGGTSGLQQPWMFAASAGLAATAGGALYLRRRNADQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF15</accession>
    <name>C7QF15_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794502.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5915"/>
    <dbReference type="EnsemblBacteria" id="ACU74773">
        <property type="protein sequence ID" value="ACU74773"/>
        <property type="gene ID" value="Caci_5915"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5915"/>
    <dbReference type="eggNOG" id="COG3938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036729_0_0_11"/>
    <dbReference type="OMA" id="SHVLWTG"/>
    <dbReference type="OrthoDB" id="559014at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35949" checksum="865305CA713A6560" modified="2009-10-13" version="1">MRTKHVYHAVDSHTEGMPTRVITGGVGVVPGETMMAKRLYFMEHLDHLRTLLMYEPRGHAAMSGAILQPPTRPDADYGVLYIEVSGLLPMCGHGTIGVATVLVETGMVPVVEPITTVRLDTPAGLILADVHVMDGAAKSVTIRNVPSFVERLDATVEVPGFGAITYDLAYGGNFYAIVDLDAYKLPFDRAAKNEIITAGLATMEAINAAAEPIHPLDDGIRAVHHVYFRAPGSTAQHSRHAMAIFPGWFDRSPCGTGTSARMAQLHARGELALDTDFINESFIGTRFIGRLVEQTEVAGRPAVIPTVTGRAWVTGTAQYFLDPDDPFPAGFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFH9</accession>
    <name>C7QFH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7933"/>
    <dbReference type="EnsemblBacteria" id="ACU76756">
        <property type="protein sequence ID" value="ACU76756"/>
        <property type="gene ID" value="Caci_7933"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7933"/>
    <dbReference type="eggNOG" id="COG5282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031872_1_1_11"/>
    <dbReference type="OMA" id="LFAHVPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018766">
        <property type="entry name" value="Zinicin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042271">
        <property type="entry name" value="Zinicin_2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39420">
        <property type="entry name" value="PTHR39420"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10103">
        <property type="entry name" value="Zincin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03624">
        <property type="entry name" value="TIGR03624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="537" mass="55901" checksum="568A00EFD938157F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG36</accession>
    <name>C7QG36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786306.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2094"/>
    <dbReference type="EnsemblBacteria" id="ACU71013">
        <property type="protein sequence ID" value="ACU71013"/>
        <property type="gene ID" value="Caci_2094"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2094"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_5_2_11"/>
    <dbReference type="OMA" id="ESGYMRA"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25367" checksum="A4284C2EDCE602D6" modified="2009-10-13" version="1">MKIAVIGGNGLIGTQVVKILTEGGHEAVAHSRASGLDLLTGQGLPEALTGADVVINLTNSPTFDDASPAFFQQSMDNLLAAAAAAGVGHAVILSIVGAELVPDLVYYRAKVLQEDILKAGPVPYSIVRATQFFEFMEAAMSWTADENAVRLPATLIQPMAAADVAQAVAEVSVGSPLAGTCNIAGPDVFTLAELGRITLITRGDPRPVVVDESAGLFAAASGDALIAKDGDDAIIAPTTYQDWLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR2</accession>
    <name>C7QGR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794671.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6086"/>
    <dbReference type="EnsemblBacteria" id="ACU74942">
        <property type="protein sequence ID" value="ACU74942"/>
        <property type="gene ID" value="Caci_6086"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6086"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_11"/>
    <dbReference type="OMA" id="NIDYKAY"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="23368" checksum="8BDA552A3E09EAA7" modified="2009-10-13" version="1">MAIIFITGANKGLGHEAARRLIGLRHTVLLGARDAAQGRKAADALGARFVRIDVTDDASVAAAAADVADHEGRIDVLVNNAGIHGPSGDPGSLTGADALGVFDTNVAGVVRVTSAFLPLLGASEDPAIVNVSSGMGSLAFTHDPERVESKVVAPLYSASKAALTMLTTQYAKALPGIRVNAADPGYTATDLNGNRGTQTVTEGTDAIVALATEGPGAASGRFVDRGGDIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGX3</accession>
    <name>C7QGX3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_8000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796548.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8000"/>
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        <property type="entry name" value="Ammonium_transp"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
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            <end position="32"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="380"/>
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        <source>
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        <source>
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    </evidence>
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            <dbReference type="Pfam" id="PF00909"/>
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            <dbReference type="EMBL" id="ACU76823.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="48364" checksum="9FDBB381343BC6A5" modified="2009-10-13" version="1" precursor="true">MPSAFSNGDTAWVLASSALVLLMTPGLAFFYGGMVRAKSVLNMLMMNFIAIAVVTILWVLYGWSVSFGNVGSGDGSGNGFWGGLHQWALHDIGQGFGSSTGGSLYGATGVPTIAVVCFQLMFAIITPALISGSLADRTKFVGWTVYVAGWVTLVYFPVAHWVFSPNGFINYKLHVMDFAGGTAVHINAGAAGLAMALVLGKRVGFGRDPMRPHNVPFVMLGVGLLWFGWFGFNAGSALGANGQASMVFINTQIATCTAMVGWLIAEKIQHGTFTSLGAASGAVAGLVAITPACASVSPLGAMFVGLIPGFICCYAINLKNKLGYDDSLDVVGVHLVGGILGTVLIGFFATKQMVSAYTNGAKAGLFYGGGVDQLISQIEGAGIVLGYSFVVSFILGWVLNKTIGMRISADAEVEGIDSTEHSETAYDWGRLAGSLRTALATAETAPSGPASGKPAKDADKTEGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGY7</accession>
    <name>C7QGY7_CATAD</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="4" type="ordered locus">Caci_8014</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="gene ID" value="Caci_8014"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG5305">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF2142_membrane"/>
    </dbReference>
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        <property type="entry name" value="DUF2142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
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    </feature>
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            <begin position="604"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="627" mass="65985" checksum="04C035C6757B47EC" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH23</accession>
    <name>C7QH23_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8050"/>
    <dbReference type="EnsemblBacteria" id="ACU76873">
        <property type="protein sequence ID" value="ACU76873"/>
        <property type="gene ID" value="Caci_8050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8050"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_4_1_11"/>
    <dbReference type="OMA" id="EPDRLHR"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="67"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="24856" checksum="5B57CB6C36C30C77" modified="2009-10-13" version="1">MDNSSGVGVLDKAAVVLSALEAGPTTLAGLVTATGLARPTAHRLAVALEHHRLVSRDMQGRFILGPRLQELASAAGEDRLLAAAGPVLAALRDHTGESAQLYRRQGDLRVCVAAAERMSGLRDTVPIGSALPMTAGSAAQILLAWEEPDRLHRGLQGARFTATTLAGVRRRGWAQSVAEREQGVASVSAPVRGPNNRVIAAVSVSGPIERLTRQPGRLHAQSVGEAAARLSEAVKRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHE6</accession>
    <name>C7QHE6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0130"/>
    <dbReference type="EnsemblBacteria" id="ACU69085">
        <property type="protein sequence ID" value="ACU69085"/>
        <property type="gene ID" value="Caci_0130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0130"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035417_0_0_11"/>
    <dbReference type="OMA" id="FINDLMN"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983227" evidence="1">
        <location>
            <begin position="34"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="561" mass="59594" checksum="F88EFA9F399188D5" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHL8</accession>
    <name>C7QHL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2124"/>
    <dbReference type="EnsemblBacteria" id="ACU71043">
        <property type="protein sequence ID" value="ACU71043"/>
        <property type="gene ID" value="Caci_2124"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2124"/>
    <dbReference type="eggNOG" id="COG1840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_3_2_11"/>
    <dbReference type="OMA" id="GQELAWK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980984" evidence="1">
        <location>
            <begin position="32"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="41820" checksum="C9DA8FF639D03B32" modified="2009-10-13" version="1" precursor="true">MSHVLSRPRTRRVGALIAVGGLTLTGLTACASSKSSSGAAAGSTATSAAAAAASSSCPALGAPASTAPAKADGSGGQVTIYSADGLYDAKDDKNWYNQEFKKFTALTGIHVNYSEDGSGGVETKVDSEKSNPKADVIVTLPPFIQKAEASGLLQAYSPACVDKVDPSLVDKNGEWEAVMGNYLSFIYNTKALPDGPPKTWNDLLDPKFSKKLQYSTPGVAGDGTAVMIAAIHAFGDNRDSAWSFFKQLQSNNVGPSKSTGALESKVNTGDLLVANGDVQMNYVDSTTQYPNNKIFFPAGNDGKPSTFSLPYMAGLVKGAPHADNGKKLIDFLLSEGAQLDASKVAYGFPARTDVKPTDSNYAALNALLQGVTVFPVDWNEVAQNYNSDVKAWDTATGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN1</accession>
    <name>C7QHN1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2137"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71056">
        <property type="protein sequence ID" value="ACU71056"/>
        <property type="gene ID" value="Caci_2137"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2137"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_4_11"/>
    <dbReference type="OMA" id="FCGGQGV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="236"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="440" mass="47858" checksum="80E5C490E66975F8" modified="2009-10-13" version="1">MADRPLRIALLAYKGNPFCGGQGVYVRHLSRELAKLGHTVEVLAGQPYPVLDPEPGVTLTEISSLDLYRQPDPFRTPKRGEYRDWVDMLEVGTMWTAGFPEPLTFSLRALRHLSARRGEFDVVHDNQCLGYGLLGMPRLGFPTMATIHHPIQVDRELELAAAPTKSRQASLRRWYAFTKMQTRVARRLPEIITVSSSSAAEIEQYLGVPQRRISTIPIGADTDSFAPDASVAKVPGRIVTTASADVPLKGLLPLVEALAKVRVEVDYAQLVVVGRAKEDGVVAKAIERLGLSDAVRFVHGISDAELVELIRSAEVACVPSLYEGFSLPAVEAMSCGTALVSTTGGAIPEVAGRDGETTLAVPPGDPSALAGALTRVLRDADLRARLGAAARERVLEKFTWRAAAIATAERYRALIEADRDPVDWDRMAADRLRRGRKAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ2</accession>
    <name>C7QHQ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2158"/>
    <dbReference type="EnsemblBacteria" id="ACU71077">
        <property type="protein sequence ID" value="ACU71077"/>
        <property type="gene ID" value="Caci_2158"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2158"/>
    <dbReference type="eggNOG" id="COG5278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038241_1_0_11"/>
    <dbReference type="OMA" id="PYPWAAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="477" mass="49050" checksum="E93414D93149B3E1" modified="2009-10-13" version="1" precursor="true">MTTASAQASTQVLAAAQGGAAAAAPSGPGGPGKPSGPGGPSEPAKPVRSRTDRRLVRLRASLAVGALLFGAAGIIGTQVRADGADDAKAHSGVMIQQAEQLYHSLSDADATSTTIYLHVGEAPADLLGTYNSDLQKAQAALLAATNEAGDDAAAKKALGAVASQLPQYVKLNATAAANNLLGYPVGFRYLTQASNLMQGTILPAAQSLTDTEAKNLASAEDTAKQFPFLMTVFGVLLLFALLMVQVRESRRTNRVFNVGLLAATAALVLSFAWTGIDVTVQNGHEDDARKRGSDQVSALATARILSLQARTDEMLTLVGRGTADDKETDYAGVTAASGTHTPGTEELLAAKLHDAVGIATDDTGKNLAQHAASDESSWHTLHLALRASDAQNQYQKAVDSALGQHDFAAPKPSAAASFTALQADLDQAIKHAEASFQSEADSGASALAGLEIGLGLLALAMAAAVLRGLGRRIAEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHT1</accession>
    <name>C7QHT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2187</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2187"/>
    <dbReference type="EnsemblBacteria" id="ACU71106">
        <property type="protein sequence ID" value="ACU71106"/>
        <property type="gene ID" value="Caci_2187"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2187"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_2_11"/>
    <dbReference type="OMA" id="CFITNSG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="122"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="232"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="41606" checksum="B3B46797E9F86343" modified="2009-10-13" version="1">MDHRLSEEYEALRATVEEFAHDVVAPKIGAFYEREEFPYEIVAQMGRMGLFGLPFPEEYGGMGGDYFALCLALEELARVDSSVAITLEAGVSLGAMPVYRFGTEEQKQQWLPKLCSGEMLGAFGLTEPGGGSDAGGTRTTAVLENGEWVINGTKCFITNSGTDITGLITVTAVTGTKPDGRKEISSIIVPSGTPGLTVAPKYSKVGWNASDTRELSFTDVRVPEANLLGDLGRGYANFLRTLDEGRIAIAALSTGLSQGCVDESVKYARDREAFGRPIGANQAIQFKLADMRLRAHTSRLAYYDAASRMLAGEPFKAEAAMAKLYSSESAVTNAREATQIHGGYGFMNEFPVARMWRDSKILEIGEGTSEVQRMLIARDMGLPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI81</accession>
    <name>C7QI81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4262"/>
    <dbReference type="EnsemblBacteria" id="ACU73126">
        <property type="protein sequence ID" value="ACU73126"/>
        <property type="gene ID" value="Caci_4262"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4262"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_2_11"/>
    <dbReference type="OMA" id="MYDWGKD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="30"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="16111" checksum="AC8A68E185DD6803" modified="2009-10-13" version="1">MVTIAPPRLVDRYRAGQESGERGDLFDADCPTRLLLDRIGDKWTVLVVLLLSDGPMRFTELRTRLGRVAPKVLTQSLRRMERDGLVTRQVFAEVPPRVEYTLTELGHSLAEPIAVIGDWAEVNMPRLTAAQQAYDAAHATDGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII2</accession>
    <name>C7QII2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6205"/>
    <dbReference type="EnsemblBacteria" id="ACU75059">
        <property type="protein sequence ID" value="ACU75059"/>
        <property type="gene ID" value="Caci_6205"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6205"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047003_2_0_11"/>
    <dbReference type="OMA" id="MQTWAGL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="372" mass="41940" checksum="36D70B81C6483678" modified="2009-10-13" version="1">MNVRTLSDRELNRATLDRQLLLHRSGMDAAQAVEHLVGLQTQIPPNHYVALWSRLTDFDAQAFSQRFENHEFVRISLQRSTIHTVTARDCLPLRQLLQPVQDRNLKGAFGKRLQGIDLTELAERARKFTEQEPLTLNDLGKLLAESYPEHEVQALGVAARNNLALVQVTPRGLWQQGGLPKHTTAEHWFGNTKAVPAMRAEELVLRYLTAFGPASVMDAQNWSGLTGLREVFDKLRADLVVFRSESGTELFDLPDAPRPGEDVPAPGRFLPDYDNVFIGHKDRARINDPRVPKERVFSGNTPISTFTVDGWIRGVWKVETDKKRTTATMNLTPLVPITKAQRADLEAEGGRLLEFLVPGADHDLRWHEDENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ22</accession>
    <name>C7QJ22_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5666 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784459.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0209"/>
    <dbReference type="EnsemblBacteria" id="ACU69164">
        <property type="protein sequence ID" value="ACU69164"/>
        <property type="gene ID" value="Caci_0209"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0209"/>
    <dbReference type="eggNOG" id="ENOG50339ZB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1248780_0_0_11"/>
    <dbReference type="OMA" id="RMNDETA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043724">
        <property type="entry name" value="DUF5666"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18914">
        <property type="entry name" value="DUF5666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5666" evidence="2">
        <location>
            <begin position="126"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="20242" checksum="41436ADA7D881FE6" modified="2009-10-13" version="1">MSDKPGGPAANDNNAEFELLSQAPSAPDISGQLKPARSGGAGIPKVTLGLVGAVLLAGGFVGGIAVGKSNSSSSSKPSNTAAGANRARGGYGGGFGTGGATGGAAGGTAGGATGGAAGGARGGAVTGTVTAVSGSTITVTDSTGKAVTVNTSPQTTVTIGKSGAVSDLTTGSEVTILGTPDSSGTITARSVVSGITQFGFGGRGGNRTPGAASSSPGGSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ48</accession>
    <name>C7QJ48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphodiester phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.4.46" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0237"/>
    <dbReference type="EnsemblBacteria" id="ACU69190">
        <property type="protein sequence ID" value="ACU69190"/>
        <property type="gene ID" value="Caci_0237"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0237"/>
    <dbReference type="eggNOG" id="COG0584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030006_3_0_11"/>
    <dbReference type="OMA" id="ETKHPTR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="46"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="36614" checksum="472CFD8511794F60" modified="2009-10-13" version="1">MHSLRPSEPRPSERRRSEPVSPVRQHAALRTGASGPGLPRRPALEIPVIAHRGASDDVPEHTLAAYEAALLQGADGLECDVRLTADMQLVCVHDRRVNRTSNGRGVVSTLELAQLRQLDFGSWKQPAAGEEHEYAEYPDLRREGAHRVLTLERLLQLVVEHPHRVEMAIETKHPTRYAGLVEEHLVALLDRFGLAHPRLGETSPVRVMSFSAMSVRRIRRLAPSLDTVLLLDRVPLRLRDGSLPRGVRIAGPGIHILRIHPEYVERVHSMGNRVHVWTVDQPSDIDLCVELGVDAIISNRPKAVLARLGRDGTAAAAAARHGVVELNPDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJC6</accession>
    <name>C7QJC6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="10">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">thrS</name>
        <name evidence="13" type="ordered locus">Caci_2230</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786442.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2230"/>
    <dbReference type="EnsemblBacteria" id="ACU71149">
        <property type="protein sequence ID" value="ACU71149"/>
        <property type="gene ID" value="Caci_2230"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2230"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_11"/>
    <dbReference type="OMA" id="FYYDFAY"/>
    <dbReference type="OrthoDB" id="900765at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="12">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="11">
        <location>
            <begin position="297"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU71149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="666" mass="74775" checksum="40C79D21DCE79DA0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJH1</accession>
    <name>C7QJH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2276"/>
    <dbReference type="EnsemblBacteria" id="ACU71194">
        <property type="protein sequence ID" value="ACU71194"/>
        <property type="gene ID" value="Caci_2276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2276"/>
    <dbReference type="eggNOG" id="COG0510">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068889_0_0_11"/>
    <dbReference type="OMA" id="VVTHGEP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="35"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="35321" checksum="0B0C005834C1330E" modified="2009-10-13" version="1">MLNPPVPFSEEDLCALLANSWRVQAAGLDYAPVGFGSHHWSVRDTGGGRWFVNVDTLPPEPEAAATRLRDLTNALSVPRTLRDLGYTFTVAPVPTTDGAVIAELAPHFAVSVYAHLDGESFTWQPWNDMDPDVRAEALAVVAELHAVPRSAWGSADTEDFAIPQRGTLDATIAGDVPDPALGPFADPAGKLITRHAPLLRHLLSHHDALADAARTRPDTFVLTHGEPHAGNFMRTDGRLVLIDWDTALIAPPERDLWGFGVGDPARQELYSLHWDLAETAVDLGVFSRPHTGDANERAGWINLADTLANLETTAARIDPSWTSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJI0</accession>
    <name>C7QJI0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2285"/>
    <dbReference type="EnsemblBacteria" id="ACU71203">
        <property type="protein sequence ID" value="ACU71203"/>
        <property type="gene ID" value="Caci_2285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2285"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_2_1_11"/>
    <dbReference type="OMA" id="SIYWHVG"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22960" checksum="9D0B9239684107E6" modified="2009-10-13" version="1">MTQETAKPPRAPAVTRRAVLDAATRLVEEQGVSGLSMRKLAAELGVAVTSIYWHVGNREALLDELVQEMVHGLDTLPARGTTPTARVLSLAVELRRVLREHPHLIGLVNERGLTPAMFLPSQRTLVAEISAAGLRGIRAAEVVRALQFHVIGFVLVERHTDRSPEQHPSAEELWLAEPGSDAALAGALATAVDADRLFAVATEALVRSLLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJI7</accession>
    <name>C7QJI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2292"/>
    <dbReference type="EnsemblBacteria" id="ACU71210">
        <property type="protein sequence ID" value="ACU71210"/>
        <property type="gene ID" value="Caci_2292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2292"/>
    <dbReference type="eggNOG" id="COG4420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077948_2_4_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41386">
        <property type="entry name" value="PTHR41386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="18054" checksum="0B3A2F17E2D4F75E" modified="2009-10-13" version="1">MTAQAQLKSTVKSAVRHIAPGSWRRHPGVRTGEQLTRGERAADKMRNSMGSWMFVFVAVAFLAVWMTLNVLLDTSTGHTFDAYPFILLNLVLSCVAALQGAILLIAAKRSDQVASELAQHDYEADCQSREMLQVLTEEFATLRTQHAEQSQQLAELIARLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU4</accession>
    <name>C7QJU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4318</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792911.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4318"/>
    <dbReference type="EnsemblBacteria" id="ACU73182">
        <property type="protein sequence ID" value="ACU73182"/>
        <property type="gene ID" value="Caci_4318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4318"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="KIDITAY"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="92"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="32461" checksum="5AFF29DF586F7AB8" modified="2009-10-13" version="1" precursor="true">MTTELTDASALTAAPSWAAPVLRTARTTARVLAWTVLSIAALATVVPFLWMLGVAFRTPADLYADPARLWPDRWSVSGFHAVFTQLPFFRLAVNSIVFAGGTTVLLLLIDSLCAYALARLRFRGQNFVFWTILLTLMVPFQVMLIPLFLTVFHLGWLNTFQGLIIPRSVSALGIFMLRQFFVKIPRQLDEAARVDGAGPLRIYWRIILPLARPALASLFVIQFMALWNDFLWPLVISSSTDMRTLPSALTLFSSTSGVDHAALMAGAAISLAPLAVAFLLAQRFFTEGIAATGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKH4</accession>
    <name>C7QKH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8250"/>
    <dbReference type="EnsemblBacteria" id="ACU77073">
        <property type="protein sequence ID" value="ACU77073"/>
        <property type="gene ID" value="Caci_8250"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8250"/>
    <dbReference type="HOGENOM" id="CLU_707307_0_0_11"/>
    <dbReference type="OMA" id="DERMYGL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="42002" checksum="77B1FCD885F59F6A" modified="2009-10-13" version="1">MGEYTGRRRGRAASEPSAQQPEYAYGEQPYGDPYAQPVPEYQAQGYEYAPEYVQEPGYGYQEAPSYEQYPSYEQQPGYEQQGYAEYGYPEQYQPEGYQQEVYAPEGYQQEQYQQQPYYEEPYAEPYAEPYAPDYSTEYADAYDPRDGYDPNAYDPNAYDPNAYDPNAYYPDTQDSPDVYAAYDTNAAYDTYDGYETPEPRRPALAPMAHLPYTAAATVALAVAAFVSTKAIAAVVLPLQLVVAYAVLDLAGFASRRTAVLVALPGLAGVLGTFKFQPDDAALPIAAGLGAGFVLVAADAVFRARRRGVEPGSVRSLAASASALLFSGLTGLFLPAAVLHTESVAAGAAVCALVSLLAARSRELGASRAAVVAIPVTIAALASYAAAILVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM0</accession>
    <name>C7QKM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8296"/>
    <dbReference type="EnsemblBacteria" id="ACU77119">
        <property type="protein sequence ID" value="ACU77119"/>
        <property type="gene ID" value="Caci_8296"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8296"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_636029_0_0_11"/>
    <dbReference type="OMA" id="ASAMIYR"/>
    <dbReference type="OrthoDB" id="1046684at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="45189" checksum="6CD3EC1305266FC7" modified="2009-10-13" version="1">MRLDIAPLPAAPSDPCALLFGKVKDACENTQHMVNGTPNPPGTTGGGGVTPADSITDPLGSIARGCAEAAQWVINNLSGAITKTATVNFTNLGFLKQYAIVFAASAILTVLLWLLSVVKRAVQGDSIITAIGEATGFLWMAVLASAFTPVILAGMVKITDSVSDAIGNGSTADRNGFLASFSHALDPNSGLGGGPIMLIFVSVLSMIAAALLWLELIIRAAMLYVGAALATAVYAGFVDKSMWGHIRRWIGLMISIDLIKPIIVIVLSLATAVSSGPQDSFSAVLSGLAIMILSIFASGLVYRFVPSFGDEMLTLQKDRAAKIGKAAITSAAFTSPAGTMRNGMATHANRISGAFAGGGGGGNMGSAVAGMSVGALASGAGAAAGIAAHTGRAITTRPGADGGGQGGGGGGATSGGGGGGGNTGGGANGGSATSASRLRAAAAPVVPKTPPPPRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKN0</accession>
    <name>C7QKN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796854.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8306"/>
    <dbReference type="EnsemblBacteria" id="ACU77129">
        <property type="protein sequence ID" value="ACU77129"/>
        <property type="gene ID" value="Caci_8306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8306"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066192_13_0_11"/>
    <dbReference type="OMA" id="TWSASAH"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="42"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="11717" checksum="A697D20E1E2D37C7" modified="2009-10-13" version="1">MTKPGYVKWSDVRAEHVERAGGEEAVAAGRARLLAEMTGYRLAEIRRARGMTQQQVAERMGVTKGRISQIEQGKVSGQEVLARYATALGGRLHQAIYFEDGDVAAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD4</accession>
    <name>C7PVD4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsF</name>
        <name evidence="9" type="ordered locus">Caci_0337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784585.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0337"/>
    <dbReference type="EnsemblBacteria" id="ACU69290">
        <property type="protein sequence ID" value="ACU69290"/>
        <property type="gene ID" value="Caci_0337"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0337"/>
    <dbReference type="eggNOG" id="COG0360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113441_5_3_11"/>
    <dbReference type="OMA" id="ITEASPM"/>
    <dbReference type="OrthoDB" id="1776954at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020815">
        <property type="entry name" value="Ribosomal_S6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01048">
        <property type="entry name" value="RIBOSOMAL_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="101" mass="11503" checksum="162E7929F4C0C354" modified="2009-10-13" version="1">MRQYEVMVILDPDLDERSIAPALEGFLKVIRDLGGSIEKNDIWGRRRLAYEIKTKSGKKVSEGIYAVVDVQATPDAVKEFDRQANLSETVVRTKVIRPDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM7</accession>
    <name>C7PVM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate-binding family V/XII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0431"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69383">
        <property type="protein sequence ID" value="ACU69383"/>
        <property type="gene ID" value="Caci_0431"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0431"/>
    <dbReference type="eggNOG" id="COG3584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067279_0_0_11"/>
    <dbReference type="OMA" id="RRIPEHA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982231" evidence="3">
        <location>
            <begin position="46"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="306"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="36931" checksum="039C3CE1BCEF53C3" modified="2009-10-13" version="1" precursor="true">MSLFPIRRRIPEHAPSRRPGPRLRALLGAVALTLTAFGAVGVVAAQQASAAGTSSLPTCPFWTNVTPPPRTDTPWVPPLQTAQPVNFSSRLAAPGGVTGTLTGSQVDISFNRVAGAQAYRVWRNGQAIAWVSDWGQPALTAVDNAPCQNAYYTFEAMSDQSGADSSLGQMSSPYQLNSDGAVVPWQIPVGSTVTMMVTSYNDGGMTASGYNSQLGVCAVDPRVIPWGTYFTVPGYGTCYAADIGTWIQNDTVDVWLPGSQANGWGVQHRTVTIIANPFGGPTPPPSSSPSSSPTSSPSSPPGGCTTAAWNSATAYTGGQTVSYGGHTWTAKWWTQGDVPGANSQNVWTDDGPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVS2</accession>
    <name>C7PVS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786607.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2396"/>
    <dbReference type="EnsemblBacteria" id="ACU71314">
        <property type="protein sequence ID" value="ACU71314"/>
        <property type="gene ID" value="Caci_2396"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2396"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070025_2_2_11"/>
    <dbReference type="OMA" id="HLMPYIG"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="42"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13833" checksum="3E6B678720B5B77B" modified="2009-10-13" version="1">MDFEAATLDREAGYALLDVLQDEATQNAALPGVEKLAPGFTDWIVTALFGGTYQRPALTLRERQIVNLAALTALGGVEPQLVGHVKTSERIGMSREEIVEVFVHLAPYVGVPKALAGLRAAAAAFEAADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVY5</accession>
    <name>C7PVY5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2459</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2459"/>
    <dbReference type="EnsemblBacteria" id="ACU71377">
        <property type="protein sequence ID" value="ACU71377"/>
        <property type="gene ID" value="Caci_2459"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2459"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="IQRNFTG"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="47"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="53561" checksum="D9EFCFEEF1B75654" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH2</accession>
    <name>C7PWH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794981.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6398"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75252">
        <property type="protein sequence ID" value="ACU75252"/>
        <property type="gene ID" value="Caci_6398"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6398"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_0_9_11"/>
    <dbReference type="OMA" id="LCAFRIS"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="29340" checksum="E9ED288B59445307" modified="2009-10-13" version="1">MSAAKTPRVSVVIPCAPQQPYLEETLLSVQKQTFQDWEVVLVLDGECEENRRMAAVLPDDRIQIVVTARPRSGIAAARNAGLPVCRGDLVAFCDGDDLCEPERLAHQVAEFDRRPALGMLATWSRRFDSATGADLGPRRCPSDSEELARKLLLFNTVTVSTVMARPEVVREAGNFRDAAIQCEDYDLWLRILGRAEVAALPEELVRYRVHEGQFSHRAKIMPQSGLLRREKLAAARRLGWSVSVARIKHLAWVGVQLANRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH4</accession>
    <name>C7PWH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794983.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6400"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75254">
        <property type="protein sequence ID" value="ACU75254"/>
        <property type="gene ID" value="Caci_6400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6400"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_5_11"/>
    <dbReference type="OMA" id="HEVMLVA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="207"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="389" mass="41816" checksum="2EC2E5D93DC2C093" modified="2009-10-13" version="1">MRILHIVNLGFEAGGAEKFVRMLRDGQTARGHQVRVVALEAPAGGRTVFADDLVPPVGGGPIGKLAGFVWHRGAHREVRRIMREFQPDCVHMHTIGGFSPAVFPATRGTARILTIHGPEDWTRKLLRWQVADNSGRIAPAALPRYLHLRLLMRPAYRLLGLRRIDGFAAPSRFVAGLIAADAGRVPVRVIPYAVDQAFTPAPVTEVWQTAYVGRLSPLKGADVLLEAFDILARTQPKARLVVVGDGPDRERLQARAAHLVAAGTVEFRGWLSPPEVAECLRGSALLAVPSTTPEIFGLTALEALELGRPLVASRIGALPELVGPDNGVLVAPGDAAALAEALAGLVGDAERLARLAEGSARRAEAFSLDRCLDEYEAWYREAAAAHGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWJ3</accession>
    <name>C7PWJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795002.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75273">
        <property type="protein sequence ID" value="ACU75273"/>
        <property type="gene ID" value="Caci_6419"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6419"/>
    <dbReference type="HOGENOM" id="CLU_939058_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="35088" checksum="5B360AD3C3110E4C" modified="2009-10-13" version="1">MNTPNPTPHSASRNFGPRHGFDRRGFERSGFERRSLGRHDFDRPGFERHVGFGRHDVDSPDPHTPCHHHRADPRTTRREARREQHHTEPRNQRRAPLREQHHTEFRDQRRAPRHEHHRADFHNRRREAYLDQRRAPHHEHHRADSRDQRPVDSRAQRYTADRDQRRADIRSQHHTTDRDQHRKSYCKSRRKSHHEAHHEHPRSARHEARRAARAAQASPWPTADQRTEIRAKIRANIRTDLHTTRNALSGADRALRKLTTAYTAAVNTPNPTRRDQARAILANARRDLHAILTPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWJ4</accession>
    <name>C7PWJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795003.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6420"/>
    <dbReference type="EnsemblBacteria" id="ACU75274">
        <property type="protein sequence ID" value="ACU75274"/>
        <property type="gene ID" value="Caci_6420"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6420"/>
    <dbReference type="eggNOG" id="ENOG5032T7N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2036671_0_0_11"/>
    <dbReference type="OMA" id="HFEDPKP"/>
    <dbReference type="OrthoDB" id="1693713at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="13743" checksum="0A967CEC85CD39F5" modified="2009-10-13" version="1">MNEEHGRIFREAWIAGVKAHYPGEPKPGYISPWEDTPEWEREAASAVYGQVTDFLTVSGGSASRLTREQKGRFVSLCWIAQIYQHIPDPKPSYVTDWSEQPEWQRETNCEVFEAIERQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK5</accession>
    <name>C7PWK5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
            <ecNumber evidence="2">1.8.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6433"/>
    <dbReference type="EnsemblBacteria" id="ACU75285">
        <property type="protein sequence ID" value="ACU75285"/>
        <property type="gene ID" value="Caci_6433"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6433"/>
    <dbReference type="eggNOG" id="COG0492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_8_11"/>
    <dbReference type="OMA" id="LPHRWID"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="561" mass="59623" checksum="CFAB0C1AD97079BB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT8</accession>
    <name>C7PWT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796920.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8372"/>
    <dbReference type="EnsemblBacteria" id="ACU77195">
        <property type="protein sequence ID" value="ACU77195"/>
        <property type="gene ID" value="Caci_8372"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8372"/>
    <dbReference type="HOGENOM" id="CLU_1438698_0_0_11"/>
    <dbReference type="OrthoDB" id="1684528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="19169" checksum="C31CA3342B9AFFDE" modified="2009-10-13" version="1">MPDVVSVPEAAGREALSRLLGYGQPAVAPGPVALSAGGRVLFYVADGGAQDLPELLEWLDWGGVRLDLTAVPAEELADPPVRWLHPSTVPMQRPGTDSRRGSGVSGSHTPNAPRTLNAPDTPDTPDSTDATGDAGGVRGAREGVAAALPGTARRPAYPTPGLPEAPELIALLATLAAACHRLAVAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY30</accession>
    <name>C7PY30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793219.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4629"/>
    <dbReference type="EnsemblBacteria" id="ACU73490">
        <property type="protein sequence ID" value="ACU73490"/>
        <property type="gene ID" value="Caci_4629"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4629"/>
    <dbReference type="HOGENOM" id="CLU_1892409_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14098" checksum="155CCD5736FF1DFC" modified="2009-10-13" version="1">MFVGVVLIILGGATTALLTLIRAKGAQPHLPAVTDGVVAEGTVQKIVTDDRAIIAFTDTDGNRVGYKERSKAAEKVRVGAYLPVLYDPADPAGTATILPKAYYQRQPWENTRAVLLSGGVFLAGLLIVAGVIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY82</accession>
    <name>C7PY82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795101.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6524"/>
    <dbReference type="EnsemblBacteria" id="ACU75372">
        <property type="protein sequence ID" value="ACU75372"/>
        <property type="gene ID" value="Caci_6524"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6524"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_7_0_11"/>
    <dbReference type="OMA" id="WRQTHLG"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="16981" checksum="0A94A59054CCEA12" modified="2009-10-13" version="1">MDDEQRVDLGVSLFIPYRYTEDRLFRALQDAGFDDWTLAQCRVFQRVAPSGSRLKDLADQAQMTKQSASVMIDQLENLGYVRRLPDPADGRARLIVIEERGRRAIEVVRATLDEIYTEWKTYLGTRNFTLLHQILDQLREITDPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYS2</accession>
    <name>C7PYS2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8575"/>
    <dbReference type="EnsemblBacteria" id="ACU77394">
        <property type="protein sequence ID" value="ACU77394"/>
        <property type="gene ID" value="Caci_8575"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8575"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067324_1_0_11"/>
    <dbReference type="OMA" id="HAREWGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28902" checksum="43BE54A85F44A917" modified="2009-10-13" version="1">MGRVIVSCSSPLDLAAEAFHALCESLAVPGLDVSGLAADLPSGMIRLDELQHRLLAGASQTARDAVWAEVVRRARRDETWQLAAIGMALPAIRNVAGSLARGFDGDVEELDSEILAGFLAHLAVVEIDAPGIVTKLRWAAYRAGHALVVAHRRTAEREEEISEQAHSLSRPSGHPDMVLMRAVSAEAISESDAELISATRLEGIDMEGYAALLGVSYNAVKIRRQRAEARLVAFVNGTQRPRAHEARVRTIRPAQRPALSRSAELSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC4</accession>
    <name>C7PZC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786874.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2665"/>
    <dbReference type="EnsemblBacteria" id="ACU71581">
        <property type="protein sequence ID" value="ACU71581"/>
        <property type="gene ID" value="Caci_2665"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2665"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061962_0_0_11"/>
    <dbReference type="OMA" id="HYEYEVE"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="288"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37807" checksum="337626E3E820CA6A" modified="2009-10-13" version="1">MGTTLAERRTDALVDRCHAGLTGAELSTEVLRRLPAIVPVAATFFATVDPATLLFTSASAQEPLGAAAALFLDNEFSRPDVNKFAALAEAPDPVNSLDHSTGGHRTDSPRYREIMAPLGLGDELRAALITGNHCWGVLCLHLEDADAGFSDQDLATIRHLAPHLAEGLRRATVRDAAEAGHPGAPGMLVLDGDLNVTSMSPQAEQWLALLSDGHADTLPVPVHAAAAKLLAAQSANPHPDAGQTAATLHLRTRDGQWLAIHATGLRGPAETQIGVVIEPATPADLGSLLLNAHGLTEAQTRVVALVLRGHSTREIVNRLHISANTVQEHLTAVFDQLGVRSRRELITTVLGHGGQKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ9</accession>
    <name>C7PZZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6646"/>
    <dbReference type="EnsemblBacteria" id="ACU75492">
        <property type="protein sequence ID" value="ACU75492"/>
        <property type="gene ID" value="Caci_6646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6646"/>
    <dbReference type="eggNOG" id="ENOG5031CS1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_863055_0_0_11"/>
    <dbReference type="OMA" id="RALICYG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982378" evidence="1">
        <location>
            <begin position="41"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="389" mass="41020" checksum="E0866615B5109E00" modified="2009-10-13" version="1" precursor="true">MTANNDPRRRPAMSRRALVSSAAAGIGALSVAGIVQNAQAAGSARPATPSATAGLTDTVLDAFGRHRLVALGEFHGLQEHYDALADLLADHRMAGVIDDLVVEWGNSLYQDTADCFVSGAVVENAELRPIWRNTTDSPLATGDEPIYEQLLRLVRAVNWRRPAGQRLRVLLGDSPIDWPTTTTPSQVTALRNQRDTFAAALVGREVLDKGHRALICYGAGHVTHSVKSGGGSGSTPGPSGVVALIEQQTGQSVFSIATLIPTDGDPGGMGAHLARYPRGIVIPTAGTWLGALDGGNLFPALAPGPSGQPVNIDCGVPLRALVDAGLYLGQVNELTMSRPDPAVYLDPVYWAELQRRDGLQGGLIDLSALRKEQSVVVTPQVLPPPLRCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0L4</accession>
    <name>C7Q0L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784937.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0707"/>
    <dbReference type="EnsemblBacteria" id="ACU69642">
        <property type="protein sequence ID" value="ACU69642"/>
        <property type="gene ID" value="Caci_0707"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0707"/>
    <dbReference type="eggNOG" id="ENOG5030J0W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097505_0_0_11"/>
    <dbReference type="OMA" id="AWCVRLV"/>
    <dbReference type="OrthoDB" id="1550125at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20773" checksum="77C0C713BFBF2AFD" modified="2009-10-13" version="1">MATREELIEKTRGWFTGRLPEDLFDGAPEVTVDREEITVIGRIPEPAYAEGASEAEKAATIEGRIKEFRERTRDARMAVARDAEHKFGRKVSWGVRCGDQGRLFTHLSVPVMTRLKQPERALLDTLVDGGVARSRSEALAWCVRLVEKHAGDWVGDLRDAMRKVEEVREAGPDRESGDADADADAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0P9</accession>
    <name>C7Q0P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0742"/>
    <dbReference type="EnsemblBacteria" id="ACU69677">
        <property type="protein sequence ID" value="ACU69677"/>
        <property type="gene ID" value="Caci_0742"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0742"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_0_11"/>
    <dbReference type="OMA" id="EHDELRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18266" checksum="6B820AF0D0F7AC6B" modified="2009-10-13" version="1">MTERDRPTLPDVSETSVIVVGAAIVRDDTVLCARRSAPPRLAGKWEFPGGKVEAGESDAEAVVRECREELGVEVTVGARVGADARIDDRLTLRVFLAYLEPGQPEPSPLEDHDRLAWVRRGELLDLDWLSPDVPIVGELGLMPALNTASRSDSSTGGGGRRAGKPCRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S6</accession>
    <name>C7Q0S6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="6">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="6">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784999.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0769"/>
    <dbReference type="EnsemblBacteria" id="ACU69704">
        <property type="protein sequence ID" value="ACU69704"/>
        <property type="gene ID" value="Caci_0769"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0769"/>
    <dbReference type="eggNOG" id="COG0479">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_3_0_11"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="28783" checksum="8F31F81781F303F7" modified="2009-10-13" version="1">MSTAVEEHVETSASGKAGIPMMTITVRIRRYNPEVDAAPHWVDYQVTADPTARILDSLHKIKWEQDGSLTFRRSCAHGVCGSDAMRINGKNRLACKALVKDLNPTSAITVEPIQGLPVLKDLVVDMEPFFQAYRDVKPFLIAHGNEPTRERIQSQKDRDRFDDTTKCILCAACTTSCPVFWTDGQYFGPAAIVNAHRFIFDSRDDGANERLEILNDREGVWRCRTTFNCTEACPRGIQITQAIAEVKRALITRRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0U0</accession>
    <name>C7Q0U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0783</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785013.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0783"/>
    <dbReference type="EnsemblBacteria" id="ACU69718">
        <property type="protein sequence ID" value="ACU69718"/>
        <property type="gene ID" value="Caci_0783"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0783"/>
    <dbReference type="eggNOG" id="COG3845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_0_11"/>
    <dbReference type="OMA" id="VGREMSH"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="257"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="529"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="544"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="558" mass="59468" checksum="10D67825E40BA3DC" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q114</accession>
    <name>C7Q114_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2776</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2776"/>
    <dbReference type="EnsemblBacteria" id="ACU71689">
        <property type="protein sequence ID" value="ACU71689"/>
        <property type="gene ID" value="Caci_2776"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2776"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_1_11"/>
    <dbReference type="OMA" id="EMFAQGK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="48"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27772" checksum="351E3EE0DE40C382" modified="2009-10-13" version="1">MIAIGCTAGFAAVVGVLVVTSPGWPRFRESFLSWSVFRSSMPDILRGFWLNIQIFMVAEPIILILGLGVALIRTTKSPGLLPFRLTATLYADVFRGVPTLLLILVVGFGIPALQLSGTPKDPVVLGVVALTLSYVAYVSEVFRAGLDSVHPSQRAAATALGLSERQTLRFVVLPQAIRNVVPPLLNDFSALQKDTALVSTLGVVESLRQAQIHESLTFNYTPYVGAALLFIAVTVPLARYTDRLARRAAARQQAGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q184</accession>
    <name>C7Q184_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787052.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2850"/>
    <dbReference type="EnsemblBacteria" id="ACU71759">
        <property type="protein sequence ID" value="ACU71759"/>
        <property type="gene ID" value="Caci_2850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2850"/>
    <dbReference type="eggNOG" id="ENOG5033M2S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1692316_0_0_11"/>
    <dbReference type="OMA" id="GITWYLT"/>
    <dbReference type="OrthoDB" id="2227914at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="15236" checksum="4072E743163049E4" modified="2009-10-13" version="1">MTTLIQASAVRLITEGYLVSRATATLPATATGNIFTVSGGRILIVSLVGEVTTAVQNQACTVAIGYAPTVGTGSTTALGTASSVIAAPIGTHVGINPGSATVVDLATQAGVATPAGRFLVDAGSVTITTSATNTGSVKWDLIYVPYDVGAAVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q221</accession>
    <name>C7Q221_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8743</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797282.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8743"/>
    <dbReference type="EnsemblBacteria" id="ACU77558">
        <property type="protein sequence ID" value="ACU77558"/>
        <property type="gene ID" value="Caci_8743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8743"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_9_0_11"/>
    <dbReference type="OMA" id="DINWISR"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="127"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="234"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="44725" checksum="EBD91A2C68133197" modified="2009-10-13" version="1">MQLRDTRDQQRFREELRTWLRATLPTLDPQPSQDDWPARRAYDSHWQALLHQAGYAGLNWPSAYGGRGATPTEHLIFLEESELAGAPYVGVNFVGLLHAGPTLIAEATPEQRERHIPAILRGDEIWCQGFSEPDAGSDLAALRTRAARDGDHYVVNGRKIWTSHAEVADYCELLVRTGPPDGPKHQGITWLIMPMDTPGVGLRPLMTAGGSTEFSEMILEDVRIPVANRVGEEGDGWRIAMVTFAFERGTGFVSEVVWARRRLVEIAALARENATWEDSDIRRRIARLAAEFDALWALVKRNVSEAEHSADGVPGPGSSVFKLRFSEARQHLDDVHAEVRGRDALAFDDDLCTYDGEPSYERLRSLAYTIAAGTSQVQRNIIGERILGLPKEPSAAGATKGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2G7</accession>
    <name>C7Q2G7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785104.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0876"/>
    <dbReference type="EnsemblBacteria" id="ACU69809">
        <property type="protein sequence ID" value="ACU69809"/>
        <property type="gene ID" value="Caci_0876"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0876"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023173_0_0_11"/>
    <dbReference type="OMA" id="WYGRLWG"/>
    <dbReference type="OrthoDB" id="1262147at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="677"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="704" mass="73968" checksum="862F7D980813282D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J4</accession>
    <name>C7Q2J4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785131.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0904"/>
    <dbReference type="EnsemblBacteria" id="ACU69836">
        <property type="protein sequence ID" value="ACU69836"/>
        <property type="gene ID" value="Caci_0904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0904"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="LMEHKNQ"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="150"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="150"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="27767" checksum="7C56D0E062A8133A" modified="2009-10-13" version="1">MPFPAGPGAAGAPAEVLIVDDEPGIRAVLASSLEFEGYAVRTAVDGRAALAEVERGRPDLVLLDVLMPGMDGLTACRRLRTADPTLPVLMLTARDLTGDRVAGLDAGADDYLAKPFELDELLARVRALLRRGALTGEGAESGPGALSRDDHVLEYEDLRMDTLTREVTRAGRLIDLTRTEYLLLEMFLSHPRQALTREQILRAVWGFDFEPASNSLDVYVMYVRKKTEFDDLPRLVQTVRGVGYALRTASGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3D7</accession>
    <name>C7Q3D7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6862"/>
    <dbReference type="EnsemblBacteria" id="ACU75702">
        <property type="protein sequence ID" value="ACU75702"/>
        <property type="gene ID" value="Caci_6862"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6862"/>
    <dbReference type="eggNOG" id="ENOG50343I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1701068_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="17089" checksum="6FFD131704FB2C32" modified="2009-10-13" version="1">MAKKKQRRTKSSATGSNKEPSLRQVPRHEQQYALVGDTLLDVENAFRLLRTMPRRTKPIDVTAWARLYGMDGNPHSPVQLGPAFDRAHAMSTNLARPLILATFASGPIEAEDTLLIIDGTHRLYRAFVEGRDQLPALVLTAAETSAITMARPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3X3</accession>
    <name>C7Q3X3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8918</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797455.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8918"/>
    <dbReference type="EnsemblBacteria" id="ACU77731">
        <property type="protein sequence ID" value="ACU77731"/>
        <property type="gene ID" value="Caci_8918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8918"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_17_5_11"/>
    <dbReference type="OMA" id="LREHYHY"/>
    <dbReference type="OrthoDB" id="785253at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14659">
        <property type="entry name" value="Phage_int_SAM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="165"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="492" mass="55137" checksum="E8BC8CCDE0663FBF" modified="2009-10-13" version="1">MGWVRKRISKNGTERFVANYRDIRGNTRSAGTYSTEKQAEDAAKKAENDIAAGRIGDPKRGRQKFRAYVLNTWLPNHEIECSTRQTYTYLINKHILPEFGGMRMVDVLPEHVREWMTKMAGAGVSAQSRRNAKVAMDAILTTAFNDQVTFLHAGQGVKRPTVAKKTKRIITAEQYDKLHAAIGESEHDGERMQLLTETDIETGMRWGELTEFRVKDLDPDADLITIARAVVKLDPKFHPQGKRFLVKDYPKDGEWRELKISRRLTTSLVDFAARRGLGSEDLFFEYVPPTEPKKRRRPDELPDPITLGWTEPHPKSGRQYRHGTISAYSGMKCRCQFCRDAMSAYRAERRAIGKDAPRNAPRHRDTDGHIDGDWFRKQIFYPAVEAAGISFKVTPKSLRDAHASWLLAGGADLQVAKERLGHGSITTTEQYLGTLPGAGEAALAALDAFRGRGAVADQAEPMPTAAEAVTPDMASVLKMMEELKLSVDRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q477</accession>
    <name>C7Q477_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="14" type="ordered locus">Caci_1009</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1009"/>
    <dbReference type="EnsemblBacteria" id="ACU69937">
        <property type="protein sequence ID" value="ACU69937"/>
        <property type="gene ID" value="Caci_1009"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1009"/>
    <dbReference type="eggNOG" id="ENOG5032S23">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1649067_0_0_11"/>
    <dbReference type="OMA" id="TMTRPAN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="13">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="104"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU69937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17294" checksum="40128887CC04C5E0" modified="2009-10-13" version="1">MADVSRLPGPNADFWDWQLRGSCRGTDSDLFFHPEGERGQARTSREEAAKEVCLHCPVCKPCREHALRVHEPYGVWGGMTEEERDESYAREKSAARAAKLAALAAAKNTKPARKPSTKVPVKLQAKPNGAPATAPSNGMTMTRPANAVSAGVRAKAKSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4H2</accession>
    <name>C7Q4H2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3032"/>
    <dbReference type="EnsemblBacteria" id="ACU71941">
        <property type="protein sequence ID" value="ACU71941"/>
        <property type="gene ID" value="Caci_3032"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3032"/>
    <dbReference type="eggNOG" id="COG4333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_823076_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012441">
        <property type="entry name" value="DUF1643"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07799">
        <property type="entry name" value="DUF1643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="35429" checksum="B72C214F9741F2C9" modified="2009-10-13" version="1">MPNTPFVSERHDHTAGADKAAFSPDGSYRYFLSRRWAPGPSICWVMLNPSTADAFRADNTIKRCIHFSRRAGYGALAVVNLYSLRSTNPDALWTHPDPIGPLGDQFLREQAGGRTSVITAWGTLGVGTPAAPNNRGPQVADMLADAGVSLLCLGTTANGQPKHPLYIHGDTPLEPYRVGGGVRCLSSRAVSSCPGRRAGASPKAPSSYPDRAPGAIHSASPRAASAGTSTSPLADSSSTSWAALPPGLRHRNSPSTCTARGSRATCSLSSSSYGGAGFSNTCPRWQARTSAAGALRELPATSMSCCLWWPKGAARALPLIRKGAPRHDHDSSSRSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M8</accession>
    <name>C7Q4M8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-nitropropane dioxygenase NPD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787290.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3088"/>
    <dbReference type="EnsemblBacteria" id="ACU71997">
        <property type="protein sequence ID" value="ACU71997"/>
        <property type="gene ID" value="Caci_3088"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3088"/>
    <dbReference type="eggNOG" id="COG2070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_2_4_11"/>
    <dbReference type="OMA" id="MDENTDG"/>
    <dbReference type="OrthoDB" id="275153at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="40027" checksum="1F8AA1053728BC4C" modified="2009-10-13" version="1">MRTPLSASLGLEFPLFAFSHCRDVVAAVTRAGGLGVLGAVYFTPDELETELRWLDAHTDGKPYGVDVVMPASVSTSVNEVSAKDSARTSMEETLKSYIPAKHRDFVEGILDKYEVPELPADGDHSHQLLGWTDATARPQVEVALDHPIALLASALGPLPADIVELAHRKNVRTAGLASSAHHARKQVECGVDIIVAQGTEAGGHTGEISTMVLIPEVVDAVGDTPVLAAGGIGNGRQVAAAMALGAQGAWTGSIWLTVAEADTDPRVVPKLLAASSRDTVRSRALTGKPARQLRTDWIDAWESEDSPGALPMPLQYMLVSEAHRRISRAGRTELMGMPVGQIVGSMTDVRPVREVIYQLVEEYAAAVERLGAITEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4P0</accession>
    <name>C7Q4P0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fmu (Sun) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787302.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3100"/>
    <dbReference type="EnsemblBacteria" id="ACU72009">
        <property type="protein sequence ID" value="ACU72009"/>
        <property type="gene ID" value="Caci_3100"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3100"/>
    <dbReference type="eggNOG" id="COG0144">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005316_0_3_11"/>
    <dbReference type="OMA" id="RVNRQHH"/>
    <dbReference type="OrthoDB" id="1064993at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="6">
        <location>
            <begin position="174"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="278"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="52907" checksum="1C3D4663D8610DAC" modified="2009-10-13" version="1">MAPRTSTSTADQARAAALEVLEAVRTRDAYANLLLPRLLRDRGLSGRDAAFTTELSYGTLRGLGTYDAIIAACVDRDLDAVDPVVLDALRIGAHQLLAMDVPPHAAVSTTVDLVRSVSNEGASRFANAILRRVGQGDLQEWIKRIAPNAQDDPEGFLSVSRSHPRWIVSAFWDSLQAHRGAQRAHQDIGELLDADNARPGVTLVTRPGLAQVGELTDLGALAARYSPYAAYLAGGDPGALAPVRDGRAGVQDEGSQLVATALALAPLEGRDEQWLDMCAGPGGKAALLAGLALERGASLLANEIAPHRAELVRRALRGYGDRVVGTADTHTAEVDENADADTDTDATDAVRTGSLQVIAADGIRAPWQPGSFDRVMLDAPCTGLGALRRRPESRWRRTPEDLERLTRVQRRLLSSALDSVRTGGLVAYVTCSPHLEETRDVVRQVVKARRDVERVDARPLLPGVPDLGGGPDVQLWPHLHGTDAMYLALLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q549</accession>
    <name>C7Q549_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-6A synthase (Deacetylating)</fullName>
            <ecNumber evidence="6">2.1.1.152</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.152" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795546.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6988"/>
    <dbReference type="EnsemblBacteria" id="ACU75818">
        <property type="protein sequence ID" value="ACU75818"/>
        <property type="gene ID" value="Caci_6988"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6988"/>
    <dbReference type="eggNOG" id="COG2243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098653_0_0_11"/>
    <dbReference type="OMA" id="ARHGWIM"/>
    <dbReference type="OrthoDB" id="1209876at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043819">
        <property type="term" value="F:precorrin-6A synthase (deacetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11643">
        <property type="entry name" value="Precorrin-6A-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012797">
        <property type="entry name" value="CobF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036525">
        <property type="entry name" value="CobF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02434">
        <property type="entry name" value="CobF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="28859" checksum="7AB898E5BDC17B18" modified="2009-10-13" version="1">MREILVIGLGAGDPEYVTVQAVNALNATDVFFVVDKGEEKSGLLALRQEICDRYITGDDYRMVTIPEPPRDRAAEAYTGAVDDWHVRRAELFEAAILEHLPENGRGAFLVWGDPALYDSTLRVIDHILARGAVQFTHRVIPGITSVQALAAQHRLPLNRIGEPVHITTGRRLAAGLPEGLESAVVMLDPNLACAALDDPDLHLYWGAYLGTPDEVLRSGPLLEIVEEVVALKQELRRRHGWIMDTYLVRREQTVSRAGSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q552</accession>
    <name>C7Q552_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6991</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6991"/>
    <dbReference type="EnsemblBacteria" id="ACU75821">
        <property type="protein sequence ID" value="ACU75821"/>
        <property type="gene ID" value="Caci_6991"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6991"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037625_0_0_11"/>
    <dbReference type="OMA" id="DELYFIA"/>
    <dbReference type="OrthoDB" id="854536at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="62"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="506" mass="53760" checksum="1D286E09D333C0F9" modified="2009-10-13" version="1">MLVMPEPSAARSAPPSFAAGPVIAVAVVYAAVLTALSGRYGFHRDELYFLQAGHHLAWGYVDQPPLTPLLARASTAVFGTSPMGLRVVATLAGVLIVVTVALLARETGGGRAAQLAAAAATAVSSMVLMSGHLVSTATFDLLAWLVICLLAARLLRTGDPRWYVAIGAATGIALLNKDLVLLLIASLVAAVLLVGPRRVTSRSGAWRWAAGGVALAVLIVAPNLWWQARHGWPQLTVASGIDRKDGMLNRATFIPFQFVYLAPTLAPLWIAGWLRLWRDPDLRRLRAFTIAYPLACVVVLATGGKCYYVLPLLLVLLAAGAEPVVGWATRGRSRPALLAAGVLVTAVINGVATLPVLPPSSVSTVNAVDKEQGEQVGWPRLVATVAGVWQTIPADQRSRAVILTQNYGEAGAIAMYGPRYGLPEPYSGHMSFFDWGPPPDAANGPVLLVFFRDNKVLPSQFEGCRPAATVDDGVGLSNDEQGAEIQVCAGLRGTWSDRWPALRSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q564</accession>
    <name>C7Q564_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795561.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7003"/>
    <dbReference type="EnsemblBacteria" id="ACU75833">
        <property type="protein sequence ID" value="ACU75833"/>
        <property type="gene ID" value="Caci_7003"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7003"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_2_11"/>
    <dbReference type="OMA" id="TFRWEED"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033068">
        <property type="term" value="P:macrolide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015083">
        <property type="entry name" value="Polyketide_synth_docking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036299">
        <property type="entry name" value="Polyketide_synth_docking_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08990">
        <property type="entry name" value="Docking"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101173">
        <property type="entry name" value="SSF101173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1692"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1566"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1567"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1837" mass="192073" checksum="201E30E4808EF4AF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5U2</accession>
    <name>C7Q5U2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1113"/>
    <dbReference type="EnsemblBacteria" id="ACU70039">
        <property type="protein sequence ID" value="ACU70039"/>
        <property type="gene ID" value="Caci_1113"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1113"/>
    <dbReference type="HOGENOM" id="CLU_1583543_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18669" checksum="59561971530D61FA" modified="2009-10-13" version="1">MMRDFSVYGYWPHTMERWGEVFQATSARAAEDLAQMYAAERGAALRVAGVFEGVIASVDRYTLFVDPRDVRNLDAEGLDPDVPGLQNETWTVLGLIESAKDRRWNEHTGGQRFCDHVLADSPLSAEDVVEDKARSEGGRLLVCAVFDGTRQRADALYAKFADPNVQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5V9</accession>
    <name>C7Q5V9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785350.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1130"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="EnsemblBacteria" id="ACU70056">
        <property type="protein sequence ID" value="ACU70056"/>
        <property type="gene ID" value="Caci_1130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1130"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_1_1_11"/>
    <dbReference type="OMA" id="PARGLFW"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="38537" checksum="A7E3A1E1F53770CE" modified="2009-10-13" version="1">MDSLATRIGDLVEGGVEQRVFPGAVWAVGGPDGVLEQGATGLLDPRDASRPMRADTLFDLASLTKIIAVWSGVGMLWEHAQIDLDDPLAKHLPDAAGFPLGAVTIRQFLTHTSGVPLRANLRASYGTDPDAVRLGVLREAMRRPAGEAVEYTDRSALILGFLVEQLMDRRLDEVARDTVWTPLAMTATRYGPVPSDLIAQSAPTEFDDETGEYVRGSVHDYSGRLLGVCGISGTFSHAQDLGRFLKHLLNPAASVGAVGTIGTVGFGQRWIAESLRLHTVALDPARGLFWVPSPKTATGEADVWLHYGFTGTGMWVSPSRERWAVLLTNKVYYSRDRGPMAAVRNEFRRLVFGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q643</accession>
    <name>C7Q643_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3140"/>
    <dbReference type="EnsemblBacteria" id="ACU72049">
        <property type="protein sequence ID" value="ACU72049"/>
        <property type="gene ID" value="Caci_3140"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3140"/>
    <dbReference type="eggNOG" id="ENOG502ZC0Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_923284_0_0_11"/>
    <dbReference type="OMA" id="HDARITY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="35483" checksum="AF685FDDBD658884" modified="2009-10-13" version="1">MSTQIGSSTLPPFTVSAPGVQTALAQFQSMTGSSNSTVSAVETLVLDAMSFAGIGSAVGSANNSLHTQLVGSLGKVVSFVETLTGAITTVLKDYEALDQKTADSYKSLSLAGGTTAQTAAQTTGTTATTPATTPAHPTTTPATPAAGTHQPLPNGFVTQLMQSEGSHGNQGGVDEVYGFRQSSHNGYDQIMAARQQYGQGSPQEQAVVADLLSRHADQAGAQDFTDPGIRAAIASSAHMRGIGGTRAILNSMATGDTPTTSAGSVSADNMAALQQMTPDQFQQSFHDARITYDQTVYGNTTTHVHGQAMTWWQAYGNGLTTRYNREQTQFEGYSQAAQGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6W1</accession>
    <name>C7Q6W1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795702.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7145"/>
    <dbReference type="ESTHER" id="catad-c7q6w1">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75974">
        <property type="protein sequence ID" value="ACU75974"/>
        <property type="gene ID" value="Caci_7145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7145"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024518_2_0_11"/>
    <dbReference type="OMA" id="TNEYEHN"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="46"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="423" mass="46452" checksum="772A0B9096219F69" modified="2009-10-13" version="1">MNPRLATTDHVFTVPLDHDEPGGGTIDVFAREVVDPGRGGDVDGLPWLVFLQGGPGGKSPRPGASVPGWLGRVLETHRLLLLDQRGTGRSTPVTPAVARGFGSGEELARYLSLHRADSIVRDCEHIRRALCGDQPWETLGQSYGGFITMNYLSRYPEGLRACYVTGGIPGLTTTADDVYRNTYPRVAAKNAEFYDRYPEDRATVARIAEILTTRDVRLPDGDRLTVDRLRSLGLAFGMGDGYERIHWLLDEAFARPGELSDTFLLNVSLPTGFVENPLFTVMQEPCYGQGSTPTAWAAERIKAEHPAFAADANPLMFTGEMIYPWMFRDLRALRPFAEAAEILAARNDWPALYDPKRLADNRVPLAAAVYHDDMYVPADFSLRTLSGVGAARAWITNEWEHDGGNASGGSVLARLMDMVAGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7B6</accession>
    <name>C7Q7B6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785498.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1279"/>
    <dbReference type="EnsemblBacteria" id="ACU70204">
        <property type="protein sequence ID" value="ACU70204"/>
        <property type="gene ID" value="Caci_1279"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1279"/>
    <dbReference type="eggNOG" id="COG3247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1080495_0_0_11"/>
    <dbReference type="OrthoDB" id="1936024at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046096">
        <property type="entry name" value="DUF6114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19609">
        <property type="entry name" value="DUF6114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27317" checksum="8D0668A1CCF2333A" modified="2009-10-13" version="1">MSTLDVEFSGGQEHAVVRGWRTFKVWRRSRPFWAGLWTLLAAFELWSIPFLQPLLVQHKLNIKMAGIAGVSTMAITPALIMMAAAMWFAPGYRVFAGVFTLVCALLSMVVSNFGGFLLGMLLGVFGGGLAFSWSPRLTEEQINAQARAEQAYRAALSGDMPPSARAPLGAGAPAAVGDEDLSAPYQEDLSAPYQFQAEPQEPAAGPIPGVAGYQGTRGEMTSALPQGDPTPAETVPATQSRDVVPPLPRAEDTPLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Q6</accession>
    <name>C7Q7Q6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H dehydrogenase (Quinone)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787542.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3342"/>
    <dbReference type="EnsemblBacteria" id="ACU72249">
        <property type="protein sequence ID" value="ACU72249"/>
        <property type="gene ID" value="Caci_3342"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3342"/>
    <dbReference type="eggNOG" id="COG2249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058643_1_0_11"/>
    <dbReference type="OMA" id="YPTWWYG"/>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="25099" checksum="E99808B10FF2A473" modified="2009-10-13" version="1">MRVLIVLDHPYTLASSENVPHRRSFTAAVAAAAIRGAEAAGHDVDLIDLAADGFSPVMSAADLVAWRQAGVVDPQVADYQRRLMAADHLVFAFPVWWEAMPAATKGFLDRVLTKGVVFEEMAGARGNPFSNLMPRLGGVTVLSIMTTPDKAYRWWFRDPLTKILFKGTFGKIGVKNLTWVNYDKVADRTPERRRQMLTDTEARFAAMPATAPPPAAAPSPSPAPAAPRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q863</accession>
    <name>C7Q863_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5371"/>
    <dbReference type="EnsemblBacteria" id="ACU74230">
        <property type="protein sequence ID" value="ACU74230"/>
        <property type="gene ID" value="Caci_5371"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5371"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_11"/>
    <dbReference type="OMA" id="FIITARV"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="127"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="38071" checksum="42217AF9489F0D35" modified="2009-10-13" version="1" precursor="true">MSITVSTLPDAAVPPPSPGAAAAARRRAPVIPLRYVLGRLIGAAVSMLAVVFTSFFLFRVVPGDPVRALTGGHPVSAAQMATLRHQFGIDKPLIAQFGDYAGRVVRGDLGTSYQYKRPVSGLIGSHVWATVYLVGTATLIAALLGLRIGVRSAWKHGSRSDRASTGIALVLWSMPTFWLALILIVVFGVGFGPIPGLFPTGGMNSPDVHGLFPVIWDHLRHLVLPCLTLVAVVYAQYLLTMRATLLEEVGADYLTTARAKGLREDDVRRKHAVPNAMLPAVTLVFLNLGTAVSGSILTETVFSWPGLGSLFYEALTVPDLPLLEGLFIFFAAAVIVMNLLAELLYPILDPRVRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8G5</accession>
    <name>C7Q8G5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76153">
        <property type="protein sequence ID" value="ACU76153"/>
        <property type="gene ID" value="Caci_7324"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7324"/>
    <dbReference type="HOGENOM" id="CLU_570734_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="478" mass="51744" checksum="C8E05082714A6B8A" modified="2009-10-13" version="1">MPNIVITEDSDWRKRFRALHQKEGAWREGFYTILGSELCQLWEITESMTPEEVCKQFSTALDLLLPSCPYPAKSNTYPDPEEAVQRSLRVTYNTANVPKLRDYDLPERRHWLEHDVPEAFRITESSSEGWLRTAQKTFLPLIEKELIAKGIILKTSGVEPSDEPQVGVEVEQAVGTPKVAESTAADETISTIAVADPATDDATESKAKPGRRHRKLVLAPAAVAIGLAVYAALPDTSPSTRGQSTPSFGATTVADPNGNPVGSMLGLTVTGVGSLDSTSFVFPASDTSQAHGVVSQINAFGYPNIAQELSAGAYNYGNTLISLKIDDNVPSPVAIYNIRVVSRQVVPTPSGLFVVEPASEPSTDQAAFDLDATTPKPQYYASGAFQGDFFDRAFGVDPQDGHTLNIFLKASKASYTYQLAIDYEVVGRRYTQMIPGSFQTAASLCDRANGSPYTDIYQWGTDSNPQGFTSVSATSVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8P5</accession>
    <name>C7Q8P5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785604.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1387"/>
    <dbReference type="EnsemblBacteria" id="ACU70310">
        <property type="protein sequence ID" value="ACU70310"/>
        <property type="gene ID" value="Caci_1387"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1387"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="EWGPQFG"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="31147" checksum="9ED0DF2F84887A71" modified="2009-10-13" version="1">MAGICEGRVAVVTGAGRGLGRAHALEFARQGAKVVVNDLGVGPDGRDGSDAPAQEVVAEIAKAGGEAVADHHDIATWDGAAGLVRTALDAFGQLDVLVNNAGFLRDRMLVNLSEQDWDDVVRVHLKGHFLTLRHAGAHWRDQYKFGNLNDARVVNTSSGAGLLGSVGQGNYAAAKAGIAALTIQAAAELGRYGVTVNAIAPAARTRMTEGPFSSMMAAPDSGFDAMAPENVSPLVVWLGSDRSRAVSGRVFEVEGGRIGVADGWQHGPTVDKGARWEPAELDAVVAGLIEQAPVPGAVYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q918</accession>
    <name>C7Q918_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787631.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3432"/>
    <dbReference type="EnsemblBacteria" id="ACU72338">
        <property type="protein sequence ID" value="ACU72338"/>
        <property type="gene ID" value="Caci_3432"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3432"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_2_0_11"/>
    <dbReference type="OMA" id="KLGDWEL"/>
    <dbReference type="OrthoDB" id="536745at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="51"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="37237" checksum="E76174182496CFCC" modified="2009-10-13" version="1">MADHELFELGDFALQHGDVLPGARLAYRTYGQLSGDKSNAIVFPTWFAGTHEANEWLIGEGKALDTERYFVIVPNLFGNGLSSSPSNTAPPHDRARFPHTTMYDNVRAQHRLVTERFGIGRLAMAVGTSMGAGQAYQWAVSHPDMVERLAPIAGSSHTSPHNQVFLEGIRAALTADASFNGGDYAEPPRTGLRAFARVYAGWGLSQAFYWQREYEQLGFATLEDFLIGFWESNFADWDANDLLAMIWTWQHADVGQTPGFGGDTRAALASITAKALLMPSKKDLYFPPEDEEWSAGYIPDADLRVIPGVWGHLAAGGGDPQAAAFIGAALRQLLDHTPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q959</accession>
    <name>C7Q959_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Erythronolide synthase</fullName>
            <ecNumber evidence="6">2.3.1.94</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3473</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.94" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3473"/>
    <dbReference type="EnsemblBacteria" id="ACU72379">
        <property type="protein sequence ID" value="ACU72379"/>
        <property type="gene ID" value="Caci_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3473"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_30_1_11"/>
    <dbReference type="OMA" id="RELAWGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047879">
        <property type="term" value="F:erythronolide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1718"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2314" mass="241572" checksum="492EAD45A9404446" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9B0</accession>
    <name>C7Q9B0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793985.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5397"/>
    <dbReference type="EnsemblBacteria" id="ACU74256">
        <property type="protein sequence ID" value="ACU74256"/>
        <property type="gene ID" value="Caci_5397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5397"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_993619_0_0_11"/>
    <dbReference type="OMA" id="LESCTYR"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="126"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="30911" checksum="5580FCF269A775BB" modified="2009-10-13" version="1">MKYTRIGDTDCSIAQALDVVGDWWTLLVVRDVAGGVTRFSELAAELGVSRKVLTERLAMLVDRGVLERRQYSDRPARFEYHLTDAGRGLLPVLIALQNWGAQHVMGDGTLTATSEPASAEARRVHALVGTGLPALTLPDADRAPTDPVSAGAKWTVLYTFPGSPAVDPGLAPGWSDVPGGPGCTLEARTFRDRLPEFAAADAAVVGVCTQRPEQLARFAELESLPFPLLSDQALQLAAALRLPTFRAAGADRLKRATLIVDAARTIRGVLYPVPDPAASVDEALRIVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9G4</accession>
    <name>C7Q9G4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5451</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794039.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5451"/>
    <dbReference type="EnsemblBacteria" id="ACU74310">
        <property type="protein sequence ID" value="ACU74310"/>
        <property type="gene ID" value="Caci_5451"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5451"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_625225_0_0_11"/>
    <dbReference type="OMA" id="MFFTYLR"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981485" description="FtsX domain-containing protein" evidence="8">
        <location>
            <begin position="38"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="363"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="511" mass="49615" checksum="85106F9A7135BABF" modified="2009-10-13" version="1" precursor="true">MFFSYLSRELRRRSKQAIVVALGLAIGIGLTITVSAASHGVKTAQDSVLHSLYGVGTDMTVTETAAPGSGNGGQRFSFNGPDAGTTSGTKTQATSSDNLNLSFGTKAMPADTLKKVAGVSGVQQAVGALTLTDFKIDTTVQQQITQDQAQQGQAPSSGSSRSGGTGGNGGNGGPRFGGPASGNGNANILTVTGVDTANLATGPMSALTLDSGRAFTTADSTADVAVVSASYASANKVAAGGTVTLAGTKFSVVGVASGTTQTGIFIPLQVAQTLSKQTGNVSTIYVKAASATEIDAVSAGIKTADTAATVTTAADLAKSVTGSLSSTASLANNLGKWLSIAVLAAAFAIAGLLTMSSVGRRVREFGTLKALGWSSRRVVRQVIGESVVTGLIGGVAGIALGFAGAQAINAFSPKLSATTGGASGGSGAPGGFGGGGGGGTGGGGTGGTGGRTFGGGGRGAQTVAVHLSAQVGLTILLVAVGLALLGGLVAGGLGGWRASSLRPADALRKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I9</accession>
    <name>C7Q9I9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794064.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5476"/>
    <dbReference type="EnsemblBacteria" id="ACU74335">
        <property type="protein sequence ID" value="ACU74335"/>
        <property type="gene ID" value="Caci_5476"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5476"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099730_0_0_11"/>
    <dbReference type="OMA" id="TVIHHVP"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="45"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="28195" checksum="3DC10BD45E789AE2" modified="2009-10-13" version="1">MRRTNYDTEQYQDYARGRALTKEQMEAWIGAFRALLPQGRPLTGLDVGSGTGRFAPALASAFGPVTGIEPSDRMREVAQSQSQHPDVRYLAGSAEDIPVPTAGADYAMLLLSWHHVLDKPRAARELARVVRPGGRLIIRSGYGDQMPWIWWLEHFPNGFEKDAALFPPLHQVIETFSTAGWRVRTFGPFTEPSPGTYGEMLDRLRLRTHSIFNQFTAEEMETGFERLEQAVAADPDAPAPADPAPLLSFERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J8</accession>
    <name>C7Q9J8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794073.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74344">
        <property type="protein sequence ID" value="ACU74344"/>
        <property type="gene ID" value="Caci_5485"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5485"/>
    <dbReference type="HOGENOM" id="CLU_920383_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="33309" checksum="B5C6BC75BDA40A0E" modified="2009-10-13" version="1" precursor="true">MSEDDLPRAIIVLLAVFSIVSFAAGSALEMARPDLLFRHPYWVNLLSGMTGFTTSGFIISVLFRRIQRRQQRRAFAGRAGPEINQIATDADAALWAMLGRLDEDVERGGIGEAAATVRAVRQRIDGVREIGAIVATFLHGVKGTSNQPVRRDAILFGRYESMSAAAMAAPPWEIPAYIRDEAHDHVGALVTLAEGSGLAEMTERGDTRIVLARLRRETAAWREDPDVHQLMQTTLDRLRELMIGGAHRDFETEIEVALRTYEDVATRPVSIVRSLAALAVTALELSSGDRFSKEILRELGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9P9</accession>
    <name>C7Q9P9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795946.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7392"/>
    <dbReference type="EnsemblBacteria" id="ACU76218">
        <property type="protein sequence ID" value="ACU76218"/>
        <property type="gene ID" value="Caci_7392"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7392"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_372428_0_0_11"/>
    <dbReference type="OMA" id="TRMPATH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="417"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="496"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="691"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="424"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="524"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="707"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="746" mass="74815" checksum="94CE9111090CA3E4" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q4</accession>
    <name>C7Q9Q4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7397"/>
    <dbReference type="EnsemblBacteria" id="ACU76223">
        <property type="protein sequence ID" value="ACU76223"/>
        <property type="gene ID" value="Caci_7397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7397"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145578_0_0_11"/>
    <dbReference type="OMA" id="CADRYYS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="73"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26024" checksum="B346400AF7B620E7" modified="2009-10-13" version="1">MSSGGGPGRADREGRPVGRRVVFGVMGLGALGVLGGSGVQRFLADAAQHDPTGLSNLLPLGDQFRIYTVTGGVKTPDPTTYRLSVTGLVDRPQHYSLTDLAALPQTDMVRDFQCVTGWRVPKVPWSGVRLKDMLALAGVQSSAKALRFVSFDGTYTESLTLDQAQNPDMLVALKMLGNPVSHDHGGPVRLYAAPMYGYKSIKWLSEIQVVDAVHPGYWEGYGYDIDAWVGKSNGRTGDVPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z9</accession>
    <name>C7Q9Z9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Molybdopterin dehydrogenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785691.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1474"/>
    <dbReference type="EnsemblBacteria" id="ACU70397">
        <property type="protein sequence ID" value="ACU70397"/>
        <property type="gene ID" value="Caci_1474"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1474"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_477934_0_0_11"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="234"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="56508" checksum="B381A3373B08CCB4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB5</accession>
    <name>C7QAB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tryptophan 23-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3508"/>
    <dbReference type="EnsemblBacteria" id="ACU72414">
        <property type="protein sequence ID" value="ACU72414"/>
        <property type="gene ID" value="Caci_3508"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3508"/>
    <dbReference type="eggNOG" id="COG3483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063240_0_0_11"/>
    <dbReference type="OMA" id="DFQAMQP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="29055" checksum="15C4665F43987535" modified="2009-10-13" version="1">MPVHSTATESGPDTPARPVSALSYNELNQIDHLLTLQQPIPGAPDALFFVAAHQITELWFKVILHELDAARLAMDGNALQEARRRLARVVRGEEVLVAHLRAVGTITPGDFAILRTHLGTSSAYESVQFREIEFVSGRKDPRFLNSPRVTDAERVRLTARLREPSLVDAFEELLDRRGQPDLGEVIAGRADPELGALIEALLEHDEGFARWRHGHALMTERIIGYQAGTGGTGGVDYLRSTVGHRFFPQLWEARSALPSYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV0</accession>
    <name>C7QAV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794152.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5564"/>
    <dbReference type="EnsemblBacteria" id="ACU74423">
        <property type="protein sequence ID" value="ACU74423"/>
        <property type="gene ID" value="Caci_5564"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5564"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="TADWANT"/>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20909" checksum="2D019A92F0CBCCFE" modified="2009-10-13" version="1">MRKLIATVFNYSLDGLLADEDTEFWRFCFDQPENNQPDDPEHLEFLRGADAHVMGRAAYEGISAAMTVHATDHPFAGILTAGRKVVFSRSLKTADWANTTIASGDTRDEIEQLKQGGDGYIVVWGGVGLFRSLLDLDVVDELWLSVFPYIAGEGTRIFDGVPSSYALELISSTASPSGIMELRYRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ5</accession>
    <name>C7QAZ5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable cell division protein WhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">whiA</name>
        <name evidence="9" type="ordered locus">Caci_5609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cell division and chromosome segregation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WhiA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5609"/>
    <dbReference type="EnsemblBacteria" id="ACU74468">
        <property type="protein sequence ID" value="ACU74468"/>
        <property type="gene ID" value="Caci_5609"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5609"/>
    <dbReference type="eggNOG" id="COG1481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053282_0_0_11"/>
    <dbReference type="OMA" id="CDAEAAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043937">
        <property type="term" value="P:regulation of sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01420">
        <property type="entry name" value="HTH_type_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018478">
        <property type="entry name" value="Sporu_reg_WhiA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003802">
        <property type="entry name" value="Sporulation_regulator_WhiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023054">
        <property type="entry name" value="Sporulation_regulator_WhiA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039518">
        <property type="entry name" value="WhiA_LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37307">
        <property type="entry name" value="PTHR37307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02650">
        <property type="entry name" value="HTH_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14527">
        <property type="entry name" value="LAGLIDADG_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10298">
        <property type="entry name" value="WhiA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00647">
        <property type="entry name" value="DNA_bind_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WhiA_N" evidence="7">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="LAGLIDADG_WhiA" evidence="8">
        <location>
            <begin position="127"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_WhiA" evidence="6">
        <location>
            <begin position="222"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="40787" checksum="403C4CD64A065AD6" modified="2009-10-13" version="1">MAMTAAVKDELSRLAVTKPCCRKAEVASVFRYGGSLHIVSGRIAIEAELDTGAAARRLRKDIWEVYSHRAELVIQSPGGLRRGHRYQLRVTAGGEAMARQIGMVDGQGRPAFGLPPYLVNGPLCDCEAVWRGAFLAHGSLTEPGRSSALEINCPNMESAIALAGAARRLGIPGAKHREVRGSDRVVLRDGDAISALLTRLGAHEAVLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARVSRALDILGEDAPEHLAAAGRLRLDHKQASLEELGTLADPPLTKDAIAGRIRRLLAMADRRAFELGVDGTDVPASGSAYGPQSVYAKDDTGMVRLGVPVQAGAVSAEFAGQRSDDLPASTDSASVSQVGPGALSSPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC25</accession>
    <name>C7QC25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3742"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72644">
        <property type="protein sequence ID" value="ACU72644"/>
        <property type="gene ID" value="Caci_3742"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3742"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_0_0_11"/>
    <dbReference type="OMA" id="FVAQIIP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981536" evidence="1">
        <location>
            <begin position="34"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="256"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="374" mass="38862" checksum="78886001C56BD7C5" modified="2009-10-13" version="1" precursor="true">MRRQKRWFNAMVSAGAALAMTIGLVGIAGTQSAAAESNGGVKVMPLGDSITDGITVSGAYRTGLWQRFVAGGYKVDFVGSLSGGPAALGDHDHEGHSGWRIDQIDANITGWLQTYQPHTVLLHIGTNDILQNDDVSNTPNRLSGLIDHITAADPGAEVFVAQIIPLANSGQNAQVRTYNAAIPGIVSSKVSAGKHVHLVDMYDALTTSDLADGVHPTAAGYDKMAAVWYSALLSVSGSIGQPGSTGGGGAIVGTASGRCADVPNSTQTLGTQVQLWDCSGATNQQWTATSAGELRVYSGDCLDAYGKGTTPGTKVAIWSCNGQTNQQWRLNADGTITGVQSGLCLDATGAATANGTLLELWTCNGQSNQQWTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH9</accession>
    <name>C7QCH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7618"/>
    <dbReference type="EnsemblBacteria" id="ACU76442">
        <property type="protein sequence ID" value="ACU76442"/>
        <property type="gene ID" value="Caci_7618"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7618"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_0_11"/>
    <dbReference type="OMA" id="RLDHNIT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_cpsA_psr" evidence="3">
        <location>
            <begin position="211"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="4">
        <location>
            <begin position="499"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="643" mass="65286" checksum="3BD7FF5528BB992F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCK8</accession>
    <name>C7QCK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796196.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7647"/>
    <dbReference type="EnsemblBacteria" id="ACU76471">
        <property type="protein sequence ID" value="ACU76471"/>
        <property type="gene ID" value="Caci_7647"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7647"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_893377_0_0_11"/>
    <dbReference type="OMA" id="TNPEWPP"/>
    <dbReference type="OrthoDB" id="1625860at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="34445" checksum="145979C8F3B87FA6" modified="2009-10-13" version="1">MSASPREAIDYGRFAERLAAQRANQDPAKRWDLYREFQAEWGYVPTGGKRWEGGDPVEPDDEEYDEDDLASMVPPEKIPAALPEWWKLPDNSFADSWLMYWTNPEWPPTWRPDPGGYGVAEGLEPDSAFVVDPDDLRMCCFTAEYQYCNEWAYQSAEAHLDDPRVFVTTGEGWVLQADSLSEFLLLQAATRLPPALGWSACPDDDFDVVAPRIRAAMPELGFHPWRELTSALVFHGGLDTLALVDPTGEDYPIRLLGRSREALERLTAQLGGEWDITEPDPPQAAADDEDDGGSADDAGSAGDAGDANSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM5</accession>
    <name>C7QCM5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7664</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7664"/>
    <dbReference type="EnsemblBacteria" id="ACU76488">
        <property type="protein sequence ID" value="ACU76488"/>
        <property type="gene ID" value="Caci_7664"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7664"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_344457_0_0_11"/>
    <dbReference type="OMA" id="ITDCYGS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982749" evidence="3">
        <location>
            <begin position="46"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="873" mass="88274" checksum="0C978E86C56505A0" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCS4</accession>
    <name>C7QCS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">8-amino-7-oxononanoate synthase</fullName>
            <ecNumber evidence="5">2.3.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796262.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7713"/>
    <dbReference type="EnsemblBacteria" id="ACU76537">
        <property type="protein sequence ID" value="ACU76537"/>
        <property type="gene ID" value="Caci_7713"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7713"/>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_11_2_11"/>
    <dbReference type="OMA" id="MDTHGFG"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="48"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="41902" checksum="F7B3CE5C3108F665" modified="2009-10-13" version="1">MSTLDQPSQPSQPSQPSRHPLSWLSQRADERRAAGLRRILVPRAADSPLIDLAGNDYLGLTRHPEVVEGAVEAVRRWGTGSTGSRLVTGTTELHAELEAGLAAHAGMEAGLVFSSGYLANLGVITALAGRGDLIVSDSLNHASLIDAARLSRARVAITPHSDADAVAAALAERSEERALVVVESLFSVDGDTAPLRKLHEACRAHGAVLVVDEAHGFGVAGPEGRGAVFDAGLGGEPDVVVAATLSKALASQGGVILGSAELIAHLVDAARSMIFDTGLAPASAGAALAALRVIERDPGLPELVRKRSWEIYELALALGLEATAPSGAVTSIIMGAPEAAVAARDFCLERGLHVGCFRPPSVPDGKSRLRVTARADLSDLETDLIRSVLSDLADNRPSAAAHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD26</accession>
    <name>C7QD26_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="10" type="ordered locus">Caci_1815</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786030.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1815"/>
    <dbReference type="EnsemblBacteria" id="ACU70736">
        <property type="protein sequence ID" value="ACU70736"/>
        <property type="gene ID" value="Caci_1815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1815"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108412_1_0_11"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="46"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16861" checksum="192A7300CA5A0FAB" modified="2009-10-13" version="1">MHCPFCKHDDSRVVDSRSSEDGTSIRRRRQCPECGRRFTTVESAQLLVVKRSGATEPFSRDKVVGGVRKACQGRPVTEGQLAVLAQRVEDVLRAAGSAEIAAHEVGLAILVPLRELDEVAYLRFASVYRAFESLEDFEAEILMLRAERERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD27</accession>
    <name>C7QD27_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1816"/>
    <dbReference type="EnsemblBacteria" id="ACU70737">
        <property type="protein sequence ID" value="ACU70737"/>
        <property type="gene ID" value="Caci_1816"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1816"/>
    <dbReference type="HOGENOM" id="CLU_3181613_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="46" mass="4861" checksum="F315E6F5EDD01C69" modified="2009-10-13" version="1">MMKTFAELLTWGPAIQSLLNPVDGEPSRGVGMVSQDGRGKKNDGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD32</accession>
    <name>C7QD32_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786036.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1821"/>
    <dbReference type="EnsemblBacteria" id="ACU70742">
        <property type="protein sequence ID" value="ACU70742"/>
        <property type="gene ID" value="Caci_1821"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1821"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_2_11"/>
    <dbReference type="OMA" id="EMAAWRG"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16638" checksum="A62B1A1516D48D9F" modified="2009-10-13" version="1">MGDEPRWLSDQEMTAWTGFLAASALVERRIDHQLREDAGLSHTQYEILVRLSAAPDGSLRMTELAEALLNSKSGLTYQMTQLEKAGLTERRSCPTDVRGVFAVLTDAGRAKLEQAAPGHVAVVREALIDVLTPEQLAVLADGLGEVARRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD63</accession>
    <name>C7QD63_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792385.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3754"/>
    <dbReference type="EnsemblBacteria" id="ACU72656">
        <property type="protein sequence ID" value="ACU72656"/>
        <property type="gene ID" value="Caci_3754"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3754"/>
    <dbReference type="eggNOG" id="ENOG5033K19">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101331_1_0_11"/>
    <dbReference type="OMA" id="WEVARNC"/>
    <dbReference type="OrthoDB" id="2094600at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18046" checksum="E65ED658B4AF803F" modified="2009-10-13" version="1" precursor="true">MTFLAISMRTLLGVVFALALGGKLRSRRSFADFAASLREIRWLPGPARAAAPIGVVAVEAVSIVLLAVPATVPFGFALTLLTLAVFTASVGWSLRRGERVRCQCFGTDGGPMGTWEVARNCVLSVAAAAGLLASAAGPAAAAPAGSAVAAAGGALAAAMIVRWDDLRYVFSSPTTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDA9</accession>
    <name>C7QDA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3800"/>
    <dbReference type="EnsemblBacteria" id="ACU72702">
        <property type="protein sequence ID" value="ACU72702"/>
        <property type="gene ID" value="Caci_3800"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3800"/>
    <dbReference type="eggNOG" id="ENOG50341JY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1567877_0_0_11"/>
    <dbReference type="OrthoDB" id="2079056at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980858" evidence="1">
        <location>
            <begin position="33"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18275" checksum="EA6F480941D065CF" modified="2009-10-13" version="1" precursor="true">MNRPTGRRIAGVLATSAALVGGTLLGTTPAHAAWGTTYPVSVQVTYYNSTGGATQIGRADGWVQFDDGGNTFRYSFNVCRQSSYTWPRLQVAVDAGYAGPTWTEVFLENYSFPNGNPTTPTAPCYGDTDVVSGQDTYTNPWNVEFVVTGDYYGASGHGYKSSNYTVGDPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD0</accession>
    <name>C7QDD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="5">3.2.1.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3822</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 39 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3822"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72723">
        <property type="protein sequence ID" value="ACU72723"/>
        <property type="gene ID" value="Caci_3822"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3822"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028597_0_0_11"/>
    <dbReference type="OMA" id="FWWRGNV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000514">
        <property type="entry name" value="Glyco_hydro_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01229">
        <property type="entry name" value="Glyco_hydro_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00745">
        <property type="entry name" value="GLHYDRLASE39"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600514-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="57798" checksum="AE8B5BF942CE7831" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDN9</accession>
    <name>C7QDN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_5805</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794392.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5805"/>
    <dbReference type="EnsemblBacteria" id="ACU74663">
        <property type="protein sequence ID" value="ACU74663"/>
        <property type="gene ID" value="Caci_5805"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5805"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_304356_0_0_11"/>
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    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF52743"/>
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    </dbReference>
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        <property type="entry name" value="SEDOLISIN"/>
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    </dbReference>
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        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982770" evidence="7">
        <location>
            <begin position="37"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="8">
        <location>
            <begin position="244"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="998" mass="100218" checksum="D17CEE872709EFFF" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDZ1</accession>
    <name>C7QDZ1_CATAD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">Caci_7755</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7755"/>
    <dbReference type="EnsemblBacteria" id="ACU76579">
        <property type="protein sequence ID" value="ACU76579"/>
        <property type="gene ID" value="Caci_7755"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7755"/>
    <dbReference type="eggNOG" id="ENOG5032YW5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064093_2_0_11"/>
    <dbReference type="OMA" id="FDWWLEW"/>
    <dbReference type="OrthoDB" id="954828at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="36899" checksum="53E35543E3C82BA8" modified="2009-10-13" version="1">MAAKTRNDVLRVNMDPALSDLALAEARDALASGDWGPARDVLAETRRALEGPQWDRRSHRVRVLAEAVANSSWVERWQVLEPVNPDAALLRAQVETVRALRGSLAGGTGYHETAAEALDLCTHAAEMAPQDPTPWVVMLTLARAADRGRRTGHDEFWHRWQQMRGRDAFNRDGQHEALMYLFGAWCGSHEEMYDFAYWLAGEAPPGSPLAALPLVAHAEVYRTANLGVTRPRQSSPQAHWSRDLVTADVDRVLRSWLGSAIEPHAQADLDRNYLLHAMVYSGLVDTDETRALFDAIGSHAMRVPWSYTGDPESSFLYWRDQAFHATAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE10</accession>
    <name>C7QE10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7774"/>
    <dbReference type="EnsemblBacteria" id="ACU76598">
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        <property type="gene ID" value="Caci_7774"/>
    </dbReference>
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    <dbReference type="OMA" id="ANPYTSV"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019920">
        <property type="entry name" value="F420-binding_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03618">
        <property type="entry name" value="Rv1155_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14656" checksum="1F11FB8E44D850B6" modified="2009-10-13" version="1">MTLEISDKARALLEKPVLVNLATVRPDGAPQVNPMWFKWDGELLWFTHTSYRQKYKNIAHEPRVSISIMDPDSGYDYLEIRGVVETVEADPEATMYQTLSEWYDGKAVVPADAKDRVKIGVRPTKLSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE26</accession>
    <name>C7QE26_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796339.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76614">
        <property type="protein sequence ID" value="ACU76614"/>
        <property type="gene ID" value="Caci_7790"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7790"/>
    <dbReference type="HOGENOM" id="CLU_2506648_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="10032" checksum="5FEC33A3BB17B507" modified="2009-10-13" version="1">MSRTDHHLPVRYREGMPPRLVLLPYWRGKRRSTLAVYANRLERRARAEFRTYSVLVASTYRAGGDLEHLAEPDARPRHGACWDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA2</accession>
    <name>C7QEA2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase</fullName>
            <ecNumber evidence="3">1.17.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.17.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786087.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1873"/>
    <dbReference type="EnsemblBacteria" id="ACU70793">
        <property type="protein sequence ID" value="ACU70793"/>
        <property type="gene ID" value="Caci_1873"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1873"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_2_0_11"/>
    <dbReference type="OMA" id="RREHFIS"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="2">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="804" mass="86350" checksum="A6F03480BC982329" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA4</accession>
    <name>C7QEA4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786089.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1875"/>
    <dbReference type="EnsemblBacteria" id="ACU70795">
        <property type="protein sequence ID" value="ACU70795"/>
        <property type="gene ID" value="Caci_1875"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1875"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_3_1_11"/>
    <dbReference type="OMA" id="ASHESWI"/>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="31893" checksum="30ED1DDE0E11941B" modified="2009-10-13" version="1" precursor="true">MRPLTAAALQLAPHPGPLTANSVGENLNRAVELIERCVGETGADLLVLPEAVTTGFTPGIPVEELWDLMSPVPGPTTEPVQQAAQRLGVHVVHCTYERGEERGVVYNSAMLIGPTGEVLGVYRKTHLFPGETQWVTPGDSVSVVDTELGRIGLTVCFDGDFPELFRIQAVRGAEIICRPSALLRSADIWELTTRARAYDNHVYVIGANATGTDPAGVHYFGNSLIVTPIAEVVARAASHEGWAAARLDPADAMRTLTPGSDRAQTFDHLAERNLGLLDTYQKDLIGPAQTPFRLGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC2</accession>
    <name>C7QEC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786107.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1893"/>
    <dbReference type="EnsemblBacteria" id="ACU70813">
        <property type="protein sequence ID" value="ACU70813"/>
        <property type="gene ID" value="Caci_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1893"/>
    <dbReference type="eggNOG" id="COG2761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069253_0_2_11"/>
    <dbReference type="OMA" id="IEWHPFQ"/>
    <dbReference type="OrthoDB" id="996965at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="25798" checksum="3AFCE33ED9242ED3" modified="2009-10-13" version="1">MRVEIWSDVACPWCYIGKARFEQGLQAFDHKDDVEVVFRSFELDPQRAKGDTVQVLPMLAGKYGMSIEQAKQAEARVAANAADAGLGYLAEGRDHGNTFDIHRVLHFAKTRGKQNELLDLAYEANFADERSIFDDDRLIELAVKAGLDETEVRTVLADATAFAADVRADEQEAQALGANGVPFFVLDRKFGVSGGQPAEVFTQALQEAWAAHTPALKLVGEAASPDGAVCGPDGCEIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEL3</accession>
    <name>C7QEL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792512.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72783">
        <property type="protein sequence ID" value="ACU72783"/>
        <property type="gene ID" value="Caci_3895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3895"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_0_11"/>
    <dbReference type="OMA" id="TMTVFNY"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041347">
        <property type="entry name" value="MftR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17754">
        <property type="entry name" value="TetR_C_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="22494" checksum="7F51D0B59C30B49C" modified="2009-10-13" version="1">MTTEPMGLRERKKHEARLRIADAALELFAAKGFDHTTVAEVAAAADVSVKTVFNYFPAKEDLFFDRAEEVEQRWLDAVADRSPGESVLAGLRRRSLSRFDQNADGSAFRFRRVMAGSAVLQGRGQQMWAAHEDAIAAALAEAMGAAVDDPTPQVLASQALGTHPLALRMAERWSDAGLAAEEVQRRVLDLINRWYDVLEEGIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER0</accession>
    <name>C7QER0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3947"/>
    <dbReference type="EnsemblBacteria" id="ACU72830">
        <property type="protein sequence ID" value="ACU72830"/>
        <property type="gene ID" value="Caci_3947"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3947"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2231747_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="52"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="105" mass="11181" checksum="6033AA5C5894FF42" modified="2009-10-13" version="1">MPHQFGQGAGQVVVGVHRLGNEEDFADRFGVVSAFGQDFGDRAGRGDAEEGAVGVGTGARPLEIAGRLFLSHGTVRNYLGFAVAKLDARNRVDAVRRIAEEASWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET6</accession>
    <name>C7QET6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator of SigK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sigma-K anti-sigma factor RskA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3980"/>
    <dbReference type="EnsemblBacteria" id="ACU72856">
        <property type="protein sequence ID" value="ACU72856"/>
        <property type="gene ID" value="Caci_3980"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3980"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075802_1_0_11"/>
    <dbReference type="OMA" id="ASARMFM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25736" checksum="1201E7E59369FDDD" modified="2009-10-13" version="1">MDPEVHSLTGAYVCHALEPAERAAFERHLAQCATCAQEVAELQETAALLASATAQTPPARLKTAVDARIAVTRQIPPIIVHAPARPAVTRPKRRWFTALGWGLAVSLAAVTAVLGVRMDDQQHRIDQAHQQNITITTLLSAPDVHTGRVIVSTGGTGTVLLSRSNDEASITVSGLAKLSPGHTYQLWMMGPSGTRSGGLLPPGSRSSDSVLARGLGDAQTIGLTVEPTGGSAQPTTTPIMLLPMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFC9</accession>
    <name>C7QFC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7883</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7883"/>
    <dbReference type="EnsemblBacteria" id="ACU76706">
        <property type="protein sequence ID" value="ACU76706"/>
        <property type="gene ID" value="Caci_7883"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7883"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OrthoDB" id="1786282at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="100"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="315"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="646" mass="66049" checksum="70AF8C907D0E2F3A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGP1</accession>
    <name>C7QGP1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6064"/>
    <dbReference type="EnsemblBacteria" id="ACU74921">
        <property type="protein sequence ID" value="ACU74921"/>
        <property type="gene ID" value="Caci_6064"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6064"/>
    <dbReference type="HOGENOM" id="CLU_1419181_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035183">
        <property type="entry name" value="DUF5304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17230">
        <property type="entry name" value="DUF5304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="191" mass="19148" checksum="B3BD034373D851DE" modified="2009-10-13" version="1">MKTHKTVTGDGSTAVSDSQENDIPFEDIPPHAAGADSAAAAPGAGGAGGNEGAEGGESAVQGDKGPEAGTADAGGTGRAAQASEERTPPGPGSTGPTGVREDLGTLADEARKLWSALEARVVAPAVQSYPEVARHLGAAGREVAAAVRSAVRGSEQSWRDSGAGGDKAGQQEQITVERVDRIDPSEQKNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGR0</accession>
    <name>C7QGR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein ArsR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6084"/>
    <dbReference type="EnsemblBacteria" id="ACU74940">
        <property type="protein sequence ID" value="ACU74940"/>
        <property type="gene ID" value="Caci_6084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6084"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100916_0_0_11"/>
    <dbReference type="OMA" id="CAEYKIR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21161" checksum="6250548476FA017B" modified="2009-10-13" version="1">MQHVDTLTLLLHPVRLRIVHAMAGDRTRTTAELCEQLADVPKTTVYRHVGLLADGGVLDVVDEQRVHGAVERRYRMRGTRARIGAEEAAGMSVEDHRRAFAAAVAALLASFSGYLDGADADPAADSVGYRQIPLWLNPAELAEMIEELQAGIVARAGNQPTPDRGLYLLSPIFFPIEKAEDRTPDRNPATDPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGY2</accession>
    <name>C7QGY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796557.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8009"/>
    <dbReference type="EnsemblBacteria" id="ACU76832">
        <property type="protein sequence ID" value="ACU76832"/>
        <property type="gene ID" value="Caci_8009"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8009"/>
    <dbReference type="HOGENOM" id="CLU_182347_1_0_11"/>
    <dbReference type="OMA" id="RMQAEND"/>
    <dbReference type="OrthoDB" id="2079019at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7706" checksum="218BE8C77983FD66" modified="2009-10-13" version="1">MAKALLGHVAAVDHRMVSEMRRLKQRVVDLEAYVSRLEDENAALAASKYSSTGLDSEFSELEREPALSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH74</accession>
    <name>C7QH74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0058</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0058"/>
    <dbReference type="EnsemblBacteria" id="ACU69013">
        <property type="protein sequence ID" value="ACU69013"/>
        <property type="gene ID" value="Caci_0058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0058"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_9_0_11"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="128"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="234"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="43377" checksum="ACC870EEEE98E2BD" modified="2009-10-13" version="1">MQPPEHLAYTPAQRALRAELRTYFAALVTEEVHRDLRLPDTATDTARTLHRKLGADGWLGVGWPQEYGGRGLTPVEQFIFFDEAARAGCPMPLVALNTVGPTLMRFGTQEQKDLLLPGILAGEIDVAAGYSEPGAGTDLASLTTRAVLTEDGSAYAVNGQKIFTTHGDSAEYVWLACRTDPDAPKHKGISILLVDTKDPGFEATKIHTIASHYTTATYYRDVRVPVTMRVGAENAGWKLITTQLNHERVALAAVAQGVIRSFAKVQSWAMETPAADGKRVIDLPWVKTTMARAYIRISGLRLLNGQMVAALQKDQTGGHLSPADASAAKVHGTETHIEALAELIQVLGAGGILKTGSPGALLAGDLEYLYRWAVTNTFGGGANEIQREIIAMTGLAMPRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHF9</accession>
    <name>C7QHF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0143"/>
    <dbReference type="EnsemblBacteria" id="ACU69098">
        <property type="protein sequence ID" value="ACU69098"/>
        <property type="gene ID" value="Caci_0143"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0143"/>
    <dbReference type="eggNOG" id="COG3437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_1_11"/>
    <dbReference type="OMA" id="FVELYMK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="16"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22618" checksum="E571D2C8DEA43566" modified="2009-10-13" version="1">MNDAHRASAPSDGDIKILLVDDRPENLLALESILGSLGHELVTAASGEQALRAVLREEFAVILLDVRMPGMDGFEVAAHIRLRERSRDTPIIFLTAAGDGPHQTLRGYAAGAADYLTKPFDPWVLRAKVGVFAELHRKNRQLKEQAEMLRETAGVTPRMLDELSNRLGAIEGTLALLIDQSGREGPVGRLERRVVRMRAALDAVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHH8</accession>
    <name>C7QHH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784412.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0162"/>
    <dbReference type="EnsemblBacteria" id="ACU69117">
        <property type="protein sequence ID" value="ACU69117"/>
        <property type="gene ID" value="Caci_0162"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0162"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="WTNGANI"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="27607" checksum="68F2811F1D63A363" modified="2009-10-13" version="1">MDLGLRGRVAVVTGGSKGIGLAVVRTLLEEGAFVVAVSRAGSAGLGEVGGPNLLHVAGDLMDAGFAAEVVEQTVAAFGGLDILVNNAGGPPPGVVLPRGPFLGGGDVDWQAVFDFNLFAVVRLTRVALPHLIERGGTIVNVSSTLARQPATNNYEYSAAKAALSHVSKGLAEEFGPQGVRVNTVLPGVTRTNWWTDEGGVADMFAGAMGIDRDTLLDKALPESLRLSMGRIVEPQEVADAVVLLASPRSRSTNGSEFVVDGGLLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR9</accession>
    <name>C7QHR9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786387.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2175"/>
    <dbReference type="EnsemblBacteria" id="ACU71094">
        <property type="protein sequence ID" value="ACU71094"/>
        <property type="gene ID" value="Caci_2175"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2175"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_5_3_11"/>
    <dbReference type="OMA" id="QLFEHRA"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="4">
        <location>
            <begin position="231"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="375" mass="39105" checksum="714BF98EA2A801A4" modified="2009-10-13" version="1">MDFELTEDQRALVDLVDQILADHCGNERLAELEKEARGSGLGSVHDAQAWRALAAAGAVSALLPDDGDLGIMGLALLAEAVGKHTAYVPMVAAIALGALPLARFGGHADLLDAVASGSKLVTAALEEPGEPDSLITTARHGEAGSKTFVLDGAKIMVPYGDLADAILIPAALDDVPALFVVPRSALKVTSLLTTGRQPYADLELDAVSVPESALLARGTEALDWLRDLGTVAYAAEASGVCTEAVAMTARYTSTRKQFGEPIASFQAVAQRAADAFISAEALRLCVLHAAWLMDDAARGGHSASSAEISADVAIAKFHAGDAGSRVLHAAQHLHGGIGVDTDYPLHRYFVRGQQIEQTLGTATRQLLRIGAHLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV0</accession>
    <name>C7QHV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative outer membrane adhesin like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2206</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786418.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71125">
        <property type="protein sequence ID" value="ACU71125"/>
        <property type="gene ID" value="Caci_2206"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2206"/>
    <dbReference type="HOGENOM" id="CLU_1109840_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032109">
        <property type="entry name" value="Big_3_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16640">
        <property type="entry name" value="Big_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981654" evidence="2">
        <location>
            <begin position="36"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Big_3_5" evidence="3">
        <location>
            <begin position="167"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="23653" checksum="1C8D679315BEFF2B" modified="2009-10-13" version="1" precursor="true">MFRTTSTASRTRRCSGAVAAATAAALMLAPGVAFAAGQPTAPGTGHAGSKTGTHAGGKGGSGGSHAGGKAGSHKTGRPGHTTGHAGAGHTASHKTGHTGAGHSTTHPTRHAGGAAAHGTKAATHGTNASASTGGPASGGSKNPQSPTSKHSAADETATVTKLSVAKVAEDGTVTMTARVSPAHRTAGAAEATGSVEFSIDGASSGPIPLSSGRAMVQAEVGPGEHTASAKYSGDTEHAPSDSGPVGVTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI42</accession>
    <name>C7QI42_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73087">
        <property type="protein sequence ID" value="ACU73087"/>
        <property type="gene ID" value="Caci_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4223"/>
    <dbReference type="eggNOG" id="ENOG5032Y3D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841155_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="36057" checksum="8E990BC81513D8AB" modified="2009-10-13" version="1">MGTSMRFNVPPGWPAPPDGWIPDPGWQPDPSWPAAPVGWRFWVDGPTDAPTSAGSRLDEQLLKVAQWTRQRAGKHEELPAVAFSGPDPAAKWFGLAASVAKFGPVHSALSGALNSAVPGGDQVLDLVKSLYAIEDEQSRVLHSIDANVTLLKEGPYRAGRLLLSEAHRLGDRDQESHRLLESAKDRFYDAQPLASSVQERTLVELHLALVWLALSRTDDARYWLEQAYQSARVVIDSLTQQATDVKVLKSKWATTALSIYYPAGLFVVPLKLKRLWSADRANGALNAFLPVANSIAACLNSLNERPVVPALELTAAYDGTRLLREVGLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI95</accession>
    <name>C7QI95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ethyl tert-butyl ether degradation EthD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792869.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4276"/>
    <dbReference type="EnsemblBacteria" id="ACU73140">
        <property type="protein sequence ID" value="ACU73140"/>
        <property type="gene ID" value="Caci_4276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4276"/>
    <dbReference type="eggNOG" id="ENOG50342Z6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_4_1_11"/>
    <dbReference type="OMA" id="VWPKEDG"/>
    <dbReference type="OrthoDB" id="946586at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02118">
        <property type="entry name" value="TIGR02118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="106" mass="11294" checksum="323D0280B47BF993" modified="2009-10-13" version="1">MTEHVNQTKITFVYSNPADPEAFEAAYPDQLALARKLPGLLRLEAAKVWPKEDGSATPAYRLLDLYFADYAAASAAAAEAGPLVGATKQHATSGVILAFAEVLETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QID7</accession>
    <name>C7QID7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)</text>
            <dbReference type="Rhea" id="RHEA:39663"/>
            <dbReference type="Rhea" id="RHEA-COMP:12939"/>
            <dbReference type="Rhea" id="RHEA-COMP:14378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:133980"/>
            <dbReference type="ChEBI" id="CHEBI:139511"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the F420H(2)-dependent quinone reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794743.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6160"/>
    <dbReference type="EnsemblBacteria" id="ACU75014">
        <property type="protein sequence ID" value="ACU75014"/>
        <property type="gene ID" value="Caci_6160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6160"/>
    <dbReference type="eggNOG" id="COG3945">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114921_2_0_11"/>
    <dbReference type="OMA" id="KHPAWVH"/>
    <dbReference type="OrthoDB" id="1693553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004378">
        <property type="entry name" value="F420H2_quin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04075">
        <property type="entry name" value="F420H2_quin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00026">
        <property type="entry name" value="hi_GC_TIGR00026"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15525" checksum="CE2D3F1E0209B663" modified="2009-10-13" version="1">MSNDERQSWNEEVIKEFRANAGSVEQFGGKGLVLLHHTGAKSGAAYVTPLAGFAQDGGSWVIVASNAGRDNHPAWFHNLRANPDIALEVPGEEAVRTVKVSARVAAEDERDALYADVVAKAPQFDEYQKGTSRKIPIVVLEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE5</accession>
    <name>C7QIE5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794751.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6168"/>
    <dbReference type="EnsemblBacteria" id="ACU75022">
        <property type="protein sequence ID" value="ACU75022"/>
        <property type="gene ID" value="Caci_6168"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6168"/>
    <dbReference type="eggNOG" id="COG3612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051344_0_0_11"/>
    <dbReference type="OMA" id="GGWTVDF"/>
    <dbReference type="OrthoDB" id="1001343at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="31343" checksum="D01E83E957C262F6" modified="2009-10-13" version="1">MEIDLGAAVSFVATHARVIERRRLHLLVDGGSPAGVLAALDAYRNPDGGYGWGLEPDQRSSTSQPVAAMHALEVLATIGDDSDRATQICDWLAGHAMADGGIPFGLPCSDTAGCAPHWTGADAHTSSLQMTAQLAAQAHRVARHRKDIAEHPWLVQATSFCLDSIDRIEEAPHPYELMFVFLFLDAVADHDSRADRLFDRVLRFVVPDSPTSVPEAEGEVLHLLDFSAYAGSRSRSLFDRAAITADLHRLASQQQPDGGWQVTFPASSPAAALEWRGYATLQAVATLRGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG9</accession>
    <name>C7QIG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794775.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6192"/>
    <dbReference type="EnsemblBacteria" id="ACU75046">
        <property type="protein sequence ID" value="ACU75046"/>
        <property type="gene ID" value="Caci_6192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6192"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069129_8_1_11"/>
    <dbReference type="OMA" id="DCSCGIG"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="45"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="28067" checksum="3B572864D5ADC586" modified="2009-10-13" version="1">MRSFYDELADDYHLMFQDWNVSMEYQASVLSAVIEAGTKRSAGRVLDCSCGIGTQAIGLARMDGASMIGTDLSPRAAARAAREAAARGVSLPTAAADMGALPFRDGVFDAVLSADNSVPHLLTPDALTAGLAEMRRVLRPDGLLVLTVRDYDELRAKRPTTTAPQVSEQQAGRAIAFQLWHWHPDGERYDLEHFQMVPTPDGADKWDVRVRRATYWALRREDLAGFATAVGFRDVQWIEPLDSGYYQPILTAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIH2</accession>
    <name>C7QIH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794778.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6195"/>
    <dbReference type="EnsemblBacteria" id="ACU75049">
        <property type="protein sequence ID" value="ACU75049"/>
        <property type="gene ID" value="Caci_6195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6195"/>
    <dbReference type="eggNOG" id="ENOG502ZPT7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117657_0_0_11"/>
    <dbReference type="OMA" id="WHYEVGC"/>
    <dbReference type="OrthoDB" id="1946162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025361">
        <property type="entry name" value="DUF4265"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14085">
        <property type="entry name" value="DUF4265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18282" checksum="1BA4496D3EB7E0E8" modified="2009-10-13" version="1">MTTDGTASATSSDQGGKIKVWFRFVPREGWLPQDTEGLWAERLSDDTARIENVPFLQNGVAQGDTIRFATGDDGLFWATDRVEASGDCTVRVISIPAGPLGRSAAAVHERLSVFGLGGEVFSEDFPLVAFNVPAESDFAGIKRLLVQGQDEGWWHFEVACMTDAWQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ60</accession>
    <name>C7QJ60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784497.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69202">
        <property type="protein sequence ID" value="ACU69202"/>
        <property type="gene ID" value="Caci_0249"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0249"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_588876_0_0_11"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981027" evidence="1">
        <location>
            <begin position="31"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="464" mass="46856" checksum="A8FE3D3B99FC8C47" modified="2009-10-13" version="1" precursor="true">MKRRTSSLLTAIALVSGAAASTLAVAPAQAATDSGTCASGSEKQGPISFNPSAAVAPATIGIRVAANTIDAANGCKAVLDFGDGTSTALSTDADVAHTYTNPGDYRVTLTLQWPGYSPAVESGHLLIGGAAGQAQITRIAGADRLDTAVQISQKQWLTVDPKSSWGQAQTAVIATSGTFPDALAGGPLAAYKRGPLLLTPPNAGLYGAANDEINRVVPKGRTIFILGGYAAVSASVDQQLITEGYKVQRFAGQTRFDTALQVAKFGLGDPANVVVATGTDFPDALSAGPLAAGPRATEVAGQAPQPAAIILTNGAKFFDPSTSAYVKGKLGTANCNAVTAVGGAAVHALGALAGGLCHSELSGADRYATSAKVFGEFSLTYLVGVASGTTFADALTGAAYVANVQQPLLLTDPTHLPDPIGAYFDAMGKQAGISYVDVFGGPKAITDHVYGQIADAAHSGEYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ86</accession>
    <name>C7QJ86_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784523.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0275"/>
    <dbReference type="EnsemblBacteria" id="ACU69228">
        <property type="protein sequence ID" value="ACU69228"/>
        <property type="gene ID" value="Caci_0275"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0275"/>
    <dbReference type="eggNOG" id="ENOG5033246">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1460461_0_0_11"/>
    <dbReference type="OMA" id="WNEWLVR"/>
    <dbReference type="OrthoDB" id="1830049at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="20269" checksum="50BECFDE19BB1EBF" modified="2009-10-13" version="1">MADYQPGLVEQARQGLGFSITEMREVNAWWQRYLRARSAPRGPERFRAVLGPADSEQDLRTGDLVSRLYHWTLPVWPELRFEIVVGPGGQVWQEWLVRAPGAEPPVAPADQTLEPWQYVVGDLERMYPQVRHLPEDAPTRWQSEYGYDDGHGGVVRRRARFCYGLLQEVSEPLEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ97</accession>
    <name>C7QJ97_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0286"/>
    <dbReference type="EnsemblBacteria" id="ACU69239">
        <property type="protein sequence ID" value="ACU69239"/>
        <property type="gene ID" value="Caci_0286"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0286"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="GMSVKFQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="32592" checksum="2ABC54DAAED472C5" modified="2009-10-13" version="1">MIAISARGLRKSFGEKTVLDGIDLSVPAGTILALLGPNGAGKTTAVHLLTTYLRPDAGEIVIAGHDLAKSPQAVRRVIGVTGQFSAVDGYLTGRENLMLMADLHLLPKAVGRQRADDLLERFELTEAAGKAAATCSGGMKRKLDLAMTLVGDPKVIFLDEPTTGLDPRSRRVMWDIIRGLVAEGTTILLTTQYLDEADQLAHRVAVLDGGRIVAEGTPAELKTRIPGGHIELTFADRAELDAAALVLAPTHRDDDALTLQLAGDGRVSALRSLLQRLDDASVEVEALAVHTPDLDDVFFALTGKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJB5</accession>
    <name>C7QJB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome bd ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_0304</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784552.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0304"/>
    <dbReference type="EnsemblBacteria" id="ACU69257">
        <property type="protein sequence ID" value="ACU69257"/>
        <property type="gene ID" value="Caci_0304"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0304"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_2_11"/>
    <dbReference type="OMA" id="GWIFACT"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="439"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU69257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="52345" checksum="8107909426335313" modified="2009-10-13" version="1" precursor="true">MLGSSLSDARIETGFSLAFHIVFAVFGVGLPWLLLVTEGRWLKTRDPVWLALTRKWSRVMAVLFAIGAVSGTVLSFEFGLLWPAFMARYGGVLGLPFTLEAFAFFAEAIFVGLYLYGWKRLSPRAHWLTLWPIAISGTLSTLFIVTANSWMNVPTGVKEVGGKVVSAEPLAPLTGPGALPESLHMLLAAIMCTGGVVAAVYAVGMLRGRRDSYHRRGFRVGLVTVLAAAPLQLVVGDLAARVVEKYQPAKLAAMEALTHTQSHAPLTLGGIYDPSTGKTRFGIEIPDGLSLLTGFRTDKTIRGLDILPAKQQPATPVVHLAFDTMVGGGMAILGLAGLLAVVALWRRRKGVRPLIPLTRPWLLAGALTGPAAMAAMLAGWEVTEAGRQPWIVYGRMTVRQAATTSGGIGWSLIATIAVYLGLATALLLILRRLATGAPPELAEGAEPSGPQDPESPTHEPSGSEGDAEDSPESTETNAESTPESSPELEGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJS0</accession>
    <name>C7QJS0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-lysine N6-monooxygenase MbtG</fullName>
            <ecNumber evidence="5">1.14.13.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lysine 6-N-hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Lysine N6-hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Lysine-N-oxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Mycobactin synthase protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_4294</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine + NADPH + O2 = H2O + N(6)-hydroxy-L-lysine + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:23228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57820"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.59" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4294"/>
    <dbReference type="EnsemblBacteria" id="ACU73158">
        <property type="protein sequence ID" value="ACU73158"/>
        <property type="gene ID" value="Caci_4294"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4294"/>
    <dbReference type="eggNOG" id="COG3486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020931_0_0_11"/>
    <dbReference type="OMA" id="FYIRESF"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047091">
        <property type="term" value="F:L-lysine 6-monooxygenase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42802">
        <property type="entry name" value="PTHR42802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="K_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU73158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="48275" checksum="B39CB0B3ECCCC422" modified="2009-10-13" version="1">MHDFIAIGLGPYNLGLACLTDPIEGLNGLFLEARPEAGYAWHPGMLLPTATLQTPFMADLVTLADPTSPYSFLNFLKETGRLYPFYIRENFYPVRAEYDEYCRWAAARLRTIRFGQTVSRVEYDEAEGCYVVHSVGTDNGAVNEHRARRLVLGTGTPPHIPEPCRGIGGDLVHSADYLANRALLQSKESITVIGSGQSAAEIYLDLLADAGADTYHLSWVTRSPRFFPLEYTKLTLEMTSPDYVDYFHALPEATRYRLEAEQKGLFKGIDAVLINEIFDTLYLKSVRGQVATRLVTNTELRGASYDEAGGTYMLDLHHEEQDRGFSLATQGLVLATGYRYQVPAFLEPVRDRLRFDGGGRFDVARNYTIDVAGREIFLQNAGTHTHSITSPDLGMGAYRNSWIISEMLGRDYYPVEKTIAFQEFGAPDGLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU7</accession>
    <name>C7QJU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="6">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792914.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4321"/>
    <dbReference type="EnsemblBacteria" id="ACU73185">
        <property type="protein sequence ID" value="ACU73185"/>
        <property type="gene ID" value="Caci_4321"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4321"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="CSSHENP"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="348" mass="36654" checksum="370D60DD4F8BFCA5" modified="2009-10-13" version="1">MPPTLKDVAERAGVSIKTVSNVVNGYAFITPATRERVERAIAETGYRPNLGARNLRKGRTGFIVLAVPELDNPYFAELTGLVITAAHRRQWTVLVEQTQGSREREQAVITSMGPQRIDAAILSPLAMEPADLLSADPGTPLVLLGERDIPGPADHVAIDNVAAARTVVEHLVGIGRRRIAIIGDQPGKNGGTAALRTAGHRQALDAAGLPPDPELVVAVENYQRADGAEAMAHLLQLPEPPDAIFCCNDLLAIGAMRAAAERGVSVPHQVAVAGFDDIAEGSYSLPSLTTIAPDKAAIAEAAVDLADRRVDPIRGGRGDRDAEPQDVRAPFALKVRESTAGSAAGSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKH2</accession>
    <name>C7QKH2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8248</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8248"/>
    <dbReference type="EnsemblBacteria" id="ACU77071">
        <property type="protein sequence ID" value="ACU77071"/>
        <property type="gene ID" value="Caci_8248"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8248"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_9_4_11"/>
    <dbReference type="OMA" id="VRAWQHP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="119"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19537" checksum="9FC7CA168832D346" modified="2009-10-13" version="1">MDVASADAERLRSLYADHAGPLLGYVLKLTDGDRGRAEDVVQETFLRAWQHAEAFAPERGSPRAWLCTVARNIVVDQARARRSRPKEVGDEGLALGIAREAVVEDDHDRILLGWEVAEAMATLSPDHRAVLRETYFKGLSVAEAADVLGIPPGTVKSRTYYALRALRTAFEERGIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK9</accession>
    <name>C7QKK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8285"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77108">
        <property type="protein sequence ID" value="ACU77108"/>
        <property type="gene ID" value="Caci_8285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8285"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_426833_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="8">
        <location>
            <begin position="479"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="694" mass="73693" checksum="85E372DD1BCCC4D1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL6</accession>
    <name>C7QKL6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796840.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8292"/>
    <dbReference type="EnsemblBacteria" id="ACU77115">
        <property type="protein sequence ID" value="ACU77115"/>
        <property type="gene ID" value="Caci_8292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8292"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125060_0_0_11"/>
    <dbReference type="OMA" id="RFTWELG"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="12695" checksum="EABA861F9803C6DB" modified="2009-10-13" version="1">MTDTTTLVAGYLAAWNETDAAARAKKVAEVFVEEIEYTDPLASVHGHDELSALIGGAQAQFAGLTFRLAGEPDAHHDVVRFTWELAAGDAEALVVGFDVALIAPDGRIGAVAGFLDKVPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVE1</accession>
    <name>C7PVE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0344"/>
    <dbReference type="EnsemblBacteria" id="ACU69297">
        <property type="protein sequence ID" value="ACU69297"/>
        <property type="gene ID" value="Caci_0344"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0344"/>
    <dbReference type="eggNOG" id="COG5650">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028876_1_0_11"/>
    <dbReference type="OMA" id="RDFLIWQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016570">
        <property type="entry name" value="UCP010361"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010361">
        <property type="entry name" value="UCP010361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="482"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="523" mass="57009" checksum="CCBA54829CCFA8D2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVF6</accession>
    <name>C7PVF6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Caci_0359</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784607.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0359"/>
    <dbReference type="EnsemblBacteria" id="ACU69312">
        <property type="protein sequence ID" value="ACU69312"/>
        <property type="gene ID" value="Caci_0359"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0359"/>
    <dbReference type="eggNOG" id="COG1017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_12_0_11"/>
    <dbReference type="OMA" id="ADIHYEV"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="17" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="18">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="19">
        <location>
            <begin position="153"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU69312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="42609" checksum="9CF53F83153DEDC0" modified="2009-10-13" version="1">MLSEQSAATVRATLPVVGAAIGDITERFYARLFQAHPELLRDLFNRGNQAAGTQRLALAGSIAAFATQLVEQPGTRPDALLSRIAHKHASLGVSPAQYKVVHQHLFAAIAEVLGDAVTPDVAAAWDEVYWLMAHALIAIEGRLSTERGYLVGGTWRDWEVVGRREETADVASFLLRPVGGGTPQPFQAGQYVSVQVELPDGARQIRQYSLTSAPDAAVRQIGVKRERGTDADPAGEVSNHLHDTVQPGHVLRISAPFGDLVVDAGASEQPLLLASAGIGVTPMISILAELVNREHAAPVLVVHADRSPEAHALRSDQNILAAKLISGRTYYWYENDAGESGRVGLADLSDVEIPAGTAAFLCGPLPFMRAMREQLLAKGVPAADIHYEVFGPDLWLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVP3</accession>
    <name>C7PVP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786578.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2367"/>
    <dbReference type="EnsemblBacteria" id="ACU71285">
        <property type="protein sequence ID" value="ACU71285"/>
        <property type="gene ID" value="Caci_2367"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2367"/>
    <dbReference type="HOGENOM" id="CLU_1101335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="26671" checksum="BE2BA21A1D09F39A" modified="2009-10-13" version="1">MPVVTGVLADYARGEASESDVVRALLAHDGWYAPMLWLDETFPDRKVYDSMIPTPALGQAPAPGDLWLFTDAGQVDAAIQAGAAFAAAGGPVSGVDVFGALTRNVTEIRVNPAGPGVHGWSVGIDDAVLDFLARWISALQIETALNDSAEDLGMRLAAFEHYVVPVDDTGRPRVVALLKPPGNYVMAFTAPDLYTAHQKRDPGVTGAADMSAATLFQLADYDGVDGVVLDMKESDSFILPQDLCDAVLKLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW62</accession>
    <name>C7PW62_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ada_Zn_binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793039.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4447"/>
    <dbReference type="EnsemblBacteria" id="ACU73310">
        <property type="protein sequence ID" value="ACU73310"/>
        <property type="gene ID" value="Caci_4447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4447"/>
    <dbReference type="eggNOG" id="COG2169">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173932_0_0_11"/>
    <dbReference type="OMA" id="FRPCGHC"/>
    <dbReference type="OrthoDB" id="1895308at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ada_Zn_binding" evidence="1">
        <location>
            <begin position="26"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="10083" checksum="5D0668FE5E5D3F23" modified="2009-10-13" version="1">MSARTWTLLGSDALPYESPTPGTLGGHRRLRIYGRLDCPSALRHIAAGNYTPHRVFFADEPTALAAGYRPCARCLPERYRAWVRDREPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWL4</accession>
    <name>C7PWL4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Urease accessory protein UreF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureF</name>
        <name evidence="4" type="ordered locus">Caci_6442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795023.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6442"/>
    <dbReference type="EnsemblBacteria" id="ACU75294">
        <property type="protein sequence ID" value="ACU75294"/>
        <property type="gene ID" value="Caci_6442"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6442"/>
    <dbReference type="eggNOG" id="COG0830">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049215_3_0_11"/>
    <dbReference type="OMA" id="HCVAYET"/>
    <dbReference type="OrthoDB" id="1942614at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01385">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009467">
        <property type="entry name" value="Ureas_acces_UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="22878" checksum="53DB82AC311E9C4E" modified="2009-10-13" version="1">MNLASLLMLTDSRLPAGTHAHSGGLEAAVAAGRVLEPGDLHAFLLGRLTTTGLTGAAFSAAALEAARGPDDALLAELDAEYEARTPSPAQRRASRTLGRQLLRAVRAGWPGPALAAASAVHPDGPHQPIAFGAAGVTAGLSAHDAALACALGAVSGPANAATRLLGVDPDAVTRVLAVLEPHIQDTADAALKAALGPISELPSFSAPRLDISAEHHSTWEVRLFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWL5</accession>
    <name>C7PWL5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ureG</name>
        <name evidence="6" type="ordered locus">Caci_6443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795024.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6443"/>
    <dbReference type="EnsemblBacteria" id="ACU75295">
        <property type="protein sequence ID" value="ACU75295"/>
        <property type="gene ID" value="Caci_6443"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6443"/>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072144_1_0_11"/>
    <dbReference type="OMA" id="VDLTIYV"/>
    <dbReference type="OrthoDB" id="1134430at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="PTHR31715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="5">
        <location>
            <begin position="16"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="20"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="23832" checksum="9010B18802C6DBEF" modified="2009-10-13" version="1">MSFALGAARTGGPLRIGIGGPVGSGKTALVAALCRALRDDYALAVVTNDIYTREDAEILLRQGVLEPERISAVETGCCPHTAIRDDISANLEAVEALERRFAPLDLVLVESGGDNLTATFSKGLIDRQIFVIDVAGGDKVPRKGGPGIISSDLLVINKTDLAELVHADLDVMRRDAKRQRTDAHGTERPTVLMSLAADPLAADVAAWTTALIAQRRAGASTVRSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWQ3</accession>
    <name>C7PWQ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795062.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6483"/>
    <dbReference type="EnsemblBacteria" id="ACU75333">
        <property type="protein sequence ID" value="ACU75333"/>
        <property type="gene ID" value="Caci_6483"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6483"/>
    <dbReference type="eggNOG" id="ENOG5031YXW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073065_0_0_11"/>
    <dbReference type="OMA" id="STEIFHE"/>
    <dbReference type="OrthoDB" id="984550at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045727">
        <property type="entry name" value="DUF6081"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19559">
        <property type="entry name" value="DUF6081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="28593" checksum="D6AE7A012008AF09" modified="2009-10-13" version="1">MSQHDPTGLEAARTASPVFHDDFHKGFAAAGPGALWQVRPAAGLPAGDGAVLVSPLGLHVAPPHTDPATGEPRFADAGDQPVHVRWAALAARTSKADFPGFDAVPGTWLVLETQMSVTPFGLERIGAAADDPAVAAAALITTDRETGMVFDFMVTGGRVFAVYERLGAPDAPHAAFTYTVPVAVTQPGRSHTCVVAYDASAGTVRWILNGSNVLTVDRIGERMPDDSALTRDNGRPAAVCTPRQLAVGLGMFAEKSLGQGVRLVVRRVTVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX84</accession>
    <name>C7PX84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0483"/>
    <dbReference type="EnsemblBacteria" id="ACU69435">
        <property type="protein sequence ID" value="ACU69435"/>
        <property type="gene ID" value="Caci_0483"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0483"/>
    <dbReference type="HOGENOM" id="CLU_3041629_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="6031" checksum="99952D1C7B3EB6FD" modified="2009-10-13" version="1">MSTSMFRPARRTRFPVHVQTGGAQAVEDDDEGLDSLYRLMPIPRSVQPRVGITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXK8</accession>
    <name>C7PXK8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71461">
        <property type="protein sequence ID" value="ACU71461"/>
        <property type="gene ID" value="Caci_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2543"/>
    <dbReference type="HOGENOM" id="CLU_862471_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="32884" checksum="5020DA9B35F4558C" modified="2009-10-13" version="1">MVRNRGEAMSSVSNKVTWWDATSTAGPAVSELAGNLIVAWRGNQNSRNLTVANVIGSSGGLSGTTLRSTVLADASDHAPSLSRILTVRYTVQLAWAGINGAHSLNAADLGVNTSSWQLTGQIVGRALVAGDSVSATSGPVWTGGGAGDVNRLGVLDQSSRSVLIEETGDLVFGAPSTSDFIVDARGPAQALATDNGETLWAWTASDGALTFALVRPGFPLPTAVVRSAQASGFGPSSIEPAYPGGPLCVAWTGIDGTGALNVAALNVDAIRNGTDPISAVYTLPETSSAAPALLHRPFLRTLAIFWTGTDGAGTLNACDVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXM5</accession>
    <name>C7PXM5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination factor Rho</fullName>
            <ecNumber evidence="6">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rho</name>
        <name evidence="10" type="ordered locus">Caci_2560</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786771.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2560"/>
    <dbReference type="EnsemblBacteria" id="ACU71478">
        <property type="protein sequence ID" value="ACU71478"/>
        <property type="gene ID" value="Caci_2560"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2560"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016377_4_3_11"/>
    <dbReference type="OMA" id="TRLCRAH"/>
    <dbReference type="OrthoDB" id="1619125at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="9">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="67"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="151"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="163"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU71478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="43720" checksum="92BDB4D3C8E7633F" modified="2009-10-13" version="1">MSAPTLERPTVAVRQHQDLIQVAGILDRQDQHGFLRTTGYLPGPEDVFVPPDLIRRHGLRSGDVIEGAATQSSPATSAKSAKPAKSARSANSSKARPLVRVDAVNGRPSDESAARPHFAAMTPIHPQERLRLAGDTSRVSTRIIDLIAPIGKGQRGLIVAPPKTGKTMLLQAIAAGVTANHPECHLMVVLLDERPEEVTDMRRTVDGEVLASTFDRPIHEHIAIAELAVERAKRLAEQGQDVVILLDSITRLCRAHNNNAKSSGRTLSGGVDASAVAAPKKLFGAARNLEEGGSVTILATALVDTGSRADDYFFEELKSTGSMELRLDRSLADKRVFPALDVAASGTRREELLMPPAELDAVRKLRRVLTARTNQQAVELLLEGAKQNAGNSEFLWRITHSSSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX1</accession>
    <name>C7PYX1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispE</name>
        <name evidence="11" type="ordered locus">Caci_0590</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784822.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0590"/>
    <dbReference type="EnsemblBacteria" id="ACU69527">
        <property type="protein sequence ID" value="ACU69527"/>
        <property type="gene ID" value="Caci_0590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0590"/>
    <dbReference type="eggNOG" id="COG1947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053057_1_1_11"/>
    <dbReference type="OMA" id="ACDALWG"/>
    <dbReference type="OrthoDB" id="1938933at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="104"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="10">
        <location>
            <begin position="223"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="32117" checksum="5B641085C3BF4E19" modified="2009-10-13" version="1">MSSAAYIPDEGPRPGETESVTVRVPAKVNLALSVGPLRSDGYHDLATVFHAVGLFDEVNAAAADTLAVTCEGEGQVEVPLDDTNLAWRAAELLARTVGRSPGVRLHLTKGIPVAGGMAGGSADAAGALVACDALWGTGLSRDDLHVLAAQLGSDVPFALHGGTAMGTGRGEQITPVLARGEFHWVFAFAHDGLSTPAVFHELDRLREAAGEEATAPGVEDELLRALRAGDSTLLGAALRNDLTRPATSLRPDLRATLQAGREAGALGTLLSGSGPTCAFLAADAVAAATVAAALEAAPSVRAVRRALGPAAGAHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ98</accession>
    <name>C7PZ98_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ordered locus">Caci_2639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786848.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2639"/>
    <dbReference type="EnsemblBacteria" id="ACU71555">
        <property type="protein sequence ID" value="ACU71555"/>
        <property type="gene ID" value="Caci_2639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2639"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_3_3_11"/>
    <dbReference type="OMA" id="VACVIDA"/>
    <dbReference type="OrthoDB" id="1632367at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="35"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="23162" checksum="63036CE86C860C4A" modified="2009-10-13" version="1">MTNDTWLVDHESPILRPAPLRVVKQADGVDLAAAERAAAQFLHALGVDTETESMHGTPRRMARAYADLFSPRAFDLTTFPNEEGYDELVLARSIPMRSVCEHHLLPFTGTAHVGYLPGKRILGLSKLARVVEHFACRPQVQERLTKQIADWLQAQLSPKGVGVVIEAEHTCMTLRGVQATGSTTVTSTLLGLLRHDPSSRSEFLALTGVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0F0</accession>
    <name>C7Q0F0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797207.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8668"/>
    <dbReference type="EnsemblBacteria" id="ACU77483">
        <property type="protein sequence ID" value="ACU77483"/>
        <property type="gene ID" value="Caci_8668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8668"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_364760_0_0_11"/>
    <dbReference type="OrthoDB" id="690169at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="765" mass="80417" checksum="10FFF408080EFC13" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Q8</accession>
    <name>C7Q0Q8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ordered locus">Caci_0751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784981.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0751"/>
    <dbReference type="EnsemblBacteria" id="ACU69686">
        <property type="protein sequence ID" value="ACU69686"/>
        <property type="gene ID" value="Caci_0751"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0751"/>
    <dbReference type="eggNOG" id="COG1217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017016_4_0_11"/>
    <dbReference type="OMA" id="MSMLFTI"/>
    <dbReference type="OrthoDB" id="143460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="630" mass="69249" checksum="21B3EE28C0944207" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S2</accession>
    <name>C7Q0S2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784995.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0765"/>
    <dbReference type="EnsemblBacteria" id="ACU69700">
        <property type="protein sequence ID" value="ACU69700"/>
        <property type="gene ID" value="Caci_0765"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0765"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="VKSHTHR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="15"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="101"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="19130" checksum="C37795BEC5A4428D" modified="2009-10-13" version="1">MREAREQEFDEFVLARQQRLLRTAYLLCGDWHLAEDLTQNALAKVYVGWHRIQQVEQLDAYVHRMLFRTYVDAYRRRRKREILSSAVPDVAGTGIASDVRLTLLAALAQVTPRYRAVLVLRFWEDRSVGETADALGISVGAVKSHTHRGLQKLRSVLGDQALDLIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0W2</accession>
    <name>C7Q0W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785035.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0805"/>
    <dbReference type="EnsemblBacteria" id="ACU69740">
        <property type="protein sequence ID" value="ACU69740"/>
        <property type="gene ID" value="Caci_0805"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0805"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_17_3_11"/>
    <dbReference type="OMA" id="MFTHAAN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="459" mass="47647" checksum="D652187FC01040B5" modified="2009-10-13" version="1">MSNPAQDFAADAPSISQVAESQSLKETFRESLTVLRVSQFRLVLFERLLSTSATGISSVALSFAVLEVTRSAAHPDGNAAAVSFVLAAQLAPMLVFTLVGGVLADRFRPQRVMMAANFAAAAGEGLAALMMFTHAANTWNLLVAAVLMGTGGALFYPSSQSLIPRLVHEEKMQAASSLSRLAQSSTLMIGAALGGVLVSVFGPGWAMGLDAGLLLIGTLPLFRITVTALERVAEKAPGMVHELREGWVEVRSRTWLWAVIACYAAVLAGWFGGFLVLGPEVAKARLGGAGAWATIVSCDGLGILLGGVAGLVYQVKRPMFVGTILTFTFALPPVVMGLGGPLWAISVVSVVAGFSGEYFMILWTVALTRHIPQDKLARVYSYDALGSLSASPLGDLIAGPASNAVGTKAVQLGAGGVIIAATGLTFMSSQVRHLRADAPVISALPAPLGEEPAPGFAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Y2</accession>
    <name>C7Q0Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786950.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2744"/>
    <dbReference type="EnsemblBacteria" id="ACU71657">
        <property type="protein sequence ID" value="ACU71657"/>
        <property type="gene ID" value="Caci_2744"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2744"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OrthoDB" id="1783638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="29314" checksum="D93DA17AFB280515" modified="2009-10-13" version="1">MGNPLAIVVLVLFAVFFGLPVLWLLLATTKTTDQLVNSNPLSFGSWHALKANWDALTRYQGGTVFLWLRNSAVYAFVALAITLVASIPAGYALALTDFPGRRTLLVSTLVVMVMPSTTLVVPLFLEINAVHLIGSMWSIILPFSFYPFGVYLAYIYFNTAIPKSLLEAARLDGCTEFGAFRRVVLPLATPVIALVGFFSFVADWTNYFLPYVLLPQNTQLPIQVGLSDISVGRPELALATVLAATPVLAVFIFSQRFLVMGMLAGAAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Z5</accession>
    <name>C7Q0Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786963.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71670">
        <property type="protein sequence ID" value="ACU71670"/>
        <property type="gene ID" value="Caci_2757"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2757"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="CIAPFEL"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="179" mass="19823" checksum="34167F3D3C9860ED" modified="2009-10-13" version="1">MRSDARRNRELILSAAVDLFTEYGPAVSMEEIARSAGLGVGTLYRHFPDRQSLLYEIATDSLHRLHQHAQDVLGTTASGWEALVDIIERCVSLPLALTKSLSEIPLDTPEIDTLAARSDALILQAVIHAQKQGELRRDLTPAQVLEMLSVVVCRPGIRTDDPLITVFLDGLRAQPHRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q149</accession>
    <name>C7Q149_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787017.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2814"/>
    <dbReference type="EnsemblBacteria" id="ACU71724">
        <property type="protein sequence ID" value="ACU71724"/>
        <property type="gene ID" value="Caci_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2814"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075874_0_0_11"/>
    <dbReference type="OMA" id="PRRERMW"/>
    <dbReference type="OrthoDB" id="1681721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982413" evidence="1">
        <location>
            <begin position="31"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="33962" checksum="2A4E782B51982B96" modified="2009-10-13" version="1" precursor="true">MDRRTLLKSAVAVGAAVPAASLLGAGPAQAAISYDVAVCEQYRNQVQIYTNTSTWTTPKWIFSPGGGGWSNLSDVKFRSTAAFGEIALFTASGGNVGLLKKSASGTQGTGSLLWSASPGDNPHAIERIPNVGAIVTASTTPGKLSVYAPTAVSDPSTLALVQTISFPGAHGLWFDDVANRLWAIGQDKATSYPISGTYRSFRLGAGTNVSIGSSLGHSLDAAYNDSGLLLASRSGSVISIQKTTHVVTVIHENSSVKSFSMYQSGEAFWVQATGKDYHGDTRNWVNPNVQFFDPVGDPSFTRGLSYGAEFYKARLHNVNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q195</accession>
    <name>C7Q195_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2861"/>
    <dbReference type="EnsemblBacteria" id="ACU71770">
        <property type="protein sequence ID" value="ACU71770"/>
        <property type="gene ID" value="Caci_2861"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2861"/>
    <dbReference type="HOGENOM" id="CLU_2841732_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="65" mass="6968" checksum="C3CE08D829EC64FF" modified="2009-10-13" version="1">MAQVWVDNQQLTCVTRVEIAPLDVNNPGPVTATLTVVDPDIAIVADLAELVVREVPPPAVEYATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1E2</accession>
    <name>C7Q1E2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4810"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73671">
        <property type="protein sequence ID" value="ACU73671"/>
        <property type="gene ID" value="Caci_4810"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4810"/>
    <dbReference type="eggNOG" id="COG3525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007082_5_1_11"/>
    <dbReference type="OMA" id="QYWVDHA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981375" description="Beta-N-acetylhexosaminidase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20b" evidence="8">
        <location>
            <begin position="57"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="7">
        <location>
            <begin position="179"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="533" mass="55405" checksum="E41CAE581BD4727B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1I2</accession>
    <name>C7Q1I2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4850"/>
    <dbReference type="EnsemblBacteria" id="ACU73711">
        <property type="protein sequence ID" value="ACU73711"/>
        <property type="gene ID" value="Caci_4850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4850"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_19_2_11"/>
    <dbReference type="OMA" id="YQHALAW"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24692" checksum="B7D2A5380B089EF5" modified="2009-10-13" version="1">MTSSKTDTAALLDLDGTLVDTNYQHAIAWFRAFRDHGIVLPIWRLHRHIGMGGEQLVAAVAGEQTERELGEQVRRDHSRHFHELIGEVELMPDARRLIQELHGRGTPVVLASSAGEKDLKYFRSMLDVDDLLAGATSSSDVEAAKPEPDIICAALEKVPDAGRAVMIGDSTWDCEAARRAGVASVALLTGGFSEQELRDAGAEAVFASIGDLLDGLDQTPLAEAAPARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1T8</accession>
    <name>C7Q1T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795367.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6798"/>
    <dbReference type="EnsemblBacteria" id="ACU75639">
        <property type="protein sequence ID" value="ACU75639"/>
        <property type="gene ID" value="Caci_6798"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6798"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_0_1_11"/>
    <dbReference type="OMA" id="MALGFCA"/>
    <dbReference type="OrthoDB" id="1288126at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29064" checksum="3A04FFAC8E818040" modified="2009-10-13" version="1" precursor="true">MSRIALVTDSTACLSAQAMDALGVRAVPLEVIVRGAPHSEADPATGELLVAALRAHETATTSRPSPEDFAAAYRAAAEEGAEGVVSLHISAELSATLESAELAAKDAPIPVRVLDSRTIGMALGFAVLGAAEAGRDGEHDLDGVADIAAKRSATASAFFYVHTLEYLRRGGRIGSARALLGSALAMKPLLHMADGRVEPLEKVRTSAKAIARLEEIAVERAGGDGSSVEIAVQHLDAPERADALAARLRERLPGLTGITVCEVGAVIGAHVGPGVLGVVVAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Z1</accession>
    <name>C7Q1Z1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6851"/>
    <dbReference type="EnsemblBacteria" id="ACU75692">
        <property type="protein sequence ID" value="ACU75692"/>
        <property type="gene ID" value="Caci_6851"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6851"/>
    <dbReference type="eggNOG" id="ENOG50336WS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058041_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025855">
        <property type="entry name" value="Replic_Relax"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13814">
        <property type="entry name" value="Replic_Relax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="30193" checksum="A7BD0A8480A35079" modified="2009-10-13" version="1">MTTTPTSAADRITARDAHMLRLIAEHRVLTSSQLTTAFFNHPSKARLRIGILRDAGLIETFRPPGGRAALHCVATAKALKLLGADRSAMPPAGKAQAATAAALRPDLRHLRGVNEFFCQLIAYSRRTRGAALEEWRSEWSTAALFPGRVRADGFAHWRVGEQWCEFFFEYDTGSEPLHRLVAKLDGYDDLMHTADTCCPVLFWLPSARREQHVRQSLRAADVEVPFATASGDPEHSDVAGPIWLPSFADRRLTLAELGEAACAHLGVSHQPHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q208</accession>
    <name>C7Q208_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797269.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8730"/>
    <dbReference type="EnsemblBacteria" id="ACU77545">
        <property type="protein sequence ID" value="ACU77545"/>
        <property type="gene ID" value="Caci_8730"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8730"/>
    <dbReference type="eggNOG" id="COG3687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051636_1_1_11"/>
    <dbReference type="OMA" id="HEGSTEQ"/>
    <dbReference type="OrthoDB" id="1601417at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016516">
        <property type="entry name" value="UCP07580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39456">
        <property type="entry name" value="PTHR39456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10118">
        <property type="entry name" value="Metal_hydrol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007580">
        <property type="entry name" value="UCP07580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="34189" checksum="8B803E976E1C38E0" modified="2009-10-13" version="1">MADLKPRRVKFDWENTPLHWIPEDPYATHIINVLHLLLPAGERWFVHVYKQILPYIHDEQLKAEVKGFMGQEGTHAVAHQNVLHHMKVQGLDPDPFVAQIEWLFEQLLGDSTMPPFAREKWLRERLAIIAAIEHFTAVLGKWIVDSRGLDAAGADPVMLDLLRWHGAEEVEHRSVAYDVFMHLDGSYARRTRAMLVTSVAFAWIWGRGTKFMVAHDPHELRAGRPTAMTEREFLGRFRDAARRGRLPSLSSLVVEVPKYLKPSYHPSRHGSTQSALDYLAVSPAAVYAAELAAARKSDVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2E3</accession>
    <name>C7Q2E3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proton-translocating NADH-quinone oxidoreductase, chain L</fullName>
            <ecNumber evidence="11">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_0852</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785080.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0852"/>
    <dbReference type="EnsemblBacteria" id="ACU69785">
        <property type="protein sequence ID" value="ACU69785"/>
        <property type="gene ID" value="Caci_0852"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0852"/>
    <dbReference type="eggNOG" id="COG1009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_6_3_11"/>
    <dbReference type="OMA" id="MGICSYF"/>
    <dbReference type="OrthoDB" id="1274678at2"/>
    <dbReference type="Proteomes" id="UP000000851">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
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        <property type="entry name" value="NU5C-like"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NDH_I_L"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="30"/>
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            <begin position="31"/>
            <end position="729"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="101"/>
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            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="225"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00361"/>
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        <source>
            <dbReference type="Pfam" id="PF00662"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU69785.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="729" mass="75313" checksum="B489D24F69E643A4" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Y0</accession>
    <name>C7Q2Y0_CATAD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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            <dbReference type="EMBL" id="ACU71872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="67" mass="7577" checksum="8B31FB345D80455B" modified="2009-10-13" version="1">MSYWFELPPAQAGDRVRVRYTEGCWEAEIERISADGATVKLVQVPESAVETKSDGTTFARITWTNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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    </gene>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="Caci_4960"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="ANWFSIQ"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
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        <property type="entry name" value="Expansin_CBD_sf"/>
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    </dbReference>
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        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="45"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="63"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="34141" checksum="F2CA486F57423E19" modified="2009-10-13" version="1" precursor="true">MQGIRSLEGEPVKATHPTTHRSRWLPISTAAGLLVVAGLIAGLAMGSSSRHTADPPPAATGFATTGSGMTATPNSAPTSAEPSAPAVASGTASSASSPTVAAAHKTPGKTSTTSQTSATPTHGGAPSPTATSLAGRVQPGVTYQGVATEYSAADGDGACLFGPAADMMIAAMNELDYQNSEACGAHVLVRAANGATITVLITNECPYPCAPGQLDLSQQAFAKLADPKAGRISVTWQLVSPAAAGNVSIRYKVGSSQYWCGIQVIGERNPVARLEVAAGSGWQQLPRASYNYFLSANGAGCGKAVRITDIFGQQVTTAALPVEPDVIQPAGVQFSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q388</accession>
    <name>C7Q388_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793553.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4964"/>
    <dbReference type="EnsemblBacteria" id="ACU73824">
        <property type="protein sequence ID" value="ACU73824"/>
        <property type="gene ID" value="Caci_4964"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4964"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_1_0_11"/>
    <dbReference type="OMA" id="LNECRYC"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="20710" checksum="25176AA74806D28F" modified="2009-10-13" version="1">MPHIDVGNDQPGIRSLFFYRPETAGPLSELAETLLRAPSSLERWERELIATHVSELNECRYCATTHAAFTSAQLPDGLDLTIIRADLGTAPISDKLKALLAIAAAVQQNGKEVTAELIDRARAVEATDLEIHDTVLIAAAFCMFNRYVDGLATTVPDDPDNYSTRAQALVRDGYLPVVELARAHQAARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3A5</accession>
    <name>C7Q3A5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4981"/>
    <dbReference type="EnsemblBacteria" id="ACU73841">
        <property type="protein sequence ID" value="ACU73841"/>
        <property type="gene ID" value="Caci_4981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4981"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_14_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="28228" checksum="C4D565801BABC798" modified="2009-10-13" version="1">MTQRRGRITQAEVARLAGVSQAMVSLVLNDSDGVRVAPETRKRVEDALQQTGYAVDIMGRRLRGKSNQILGVFTYESVFPSDSTDFYGPFLGGIEEESEAQGYDLLLFTSPGRRHGRRKVYEQDSNRLGIADGCILLGRHTDREELDRLVNERFPFVFIGRRESSAGPVSYVGADYAEATAALYERAWSLGHRRIALVGYHEESESTADRRSGYLAACRRHRRKPLTLTDDDPSTGLRAAARRPDHRGTGGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3B8</accession>
    <name>C7Q3B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4994</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4994"/>
    <dbReference type="EnsemblBacteria" id="ACU73854">
        <property type="protein sequence ID" value="ACU73854"/>
        <property type="gene ID" value="Caci_4994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4994"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_6_0_11"/>
    <dbReference type="OMA" id="RTEETVH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="72"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23234" checksum="987608C728961770" modified="2009-10-13" version="1">MLAIVTRAVPAVARALDILELFLGRPTLTAAEIAAGTGLPRSTVHELMGTLIERGYAATDPGSPTRFRLGPQVLLLGSRFADRLDLAREAQSVAEAVAAECGETVQVAVLDGGFAVCVAKADSTHAVRVVAAVGSRLPVRASALGQALLAGLGTDTAAVEEVVFEHDEAGNDVRSVAAPVRDHNGRVVAALGVTVPATRPVELWSPQVRKGAAELSERLGHQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G6</accession>
    <name>C7Q3G6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795459.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6893"/>
    <dbReference type="EnsemblBacteria" id="ACU75731">
        <property type="protein sequence ID" value="ACU75731"/>
        <property type="gene ID" value="Caci_6893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6893"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068419_0_0_11"/>
    <dbReference type="OMA" id="AGALCWI"/>
    <dbReference type="OrthoDB" id="1538974at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="30878" checksum="69FCADF713D25253" modified="2009-10-13" version="1" precursor="true">MDNVTLFFTVVGALLMLIAGGALLFLAYRPPASSESWAGWLARLDPRPVLVQRRKLAVAIGVGCVVGVLSGWPVAAAAIGLAMWFAPIVMGHDVHEADRTARVEAVAVWAEMLRDVLSSAAGLEQAVLASTTVAPEAIAGPLAALGSDLRARRPFADAMRALAAQLGDATADQVIVSLIHAQKFQAKNLAELLGELAAAARAQVSLAVRVHAERAKHRTSQRAITVIFTLMALGLCVFYPKFLRPYDTVGGQMVMAVVVAMFAGALCWIQIILRPKAMPRLLDPNGWEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G8</accession>
    <name>C7Q3G8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6895"/>
    <dbReference type="EnsemblBacteria" id="ACU75733">
        <property type="protein sequence ID" value="ACU75733"/>
        <property type="gene ID" value="Caci_6895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6895"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105581_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980574" evidence="1">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="26147" checksum="74C3701A3FD76297" modified="2009-10-13" version="1">MLIGLCSLKSSPGVTTTTLAIAGCWPAHLTTPTVIELDARGGDVAWRYGMAADPGLRSLAAASRLDPQPSALAGHARPVGGSAVPTVTAPAEREPARQAVAALKPLLKVLRDERDAVLVDLGEIDPRESSTADLLGSLASLLVVARAVPEQAARVAAAASDLRLTNRNVRVLFIGDLREGDAETVAGLPTAGVLPLINPNASLFSRLADRRSRRAFGGTTVRVAEELAWTTVSREREVVTASASDGPEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Q9</accession>
    <name>C7Q3Q9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8854</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8854"/>
    <dbReference type="EnsemblBacteria" id="ACU77667">
        <property type="protein sequence ID" value="ACU77667"/>
        <property type="gene ID" value="Caci_8854"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8854"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_0_1_11"/>
    <dbReference type="OMA" id="SFRMPRI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="453" mass="44947" checksum="7DE39505DD35E548" modified="2009-10-13" version="1">MGQASADANAAAGQTAAARANPSAGEAARGSETPPMLAAGGIGEAEGSLPARADLSAGATNSPNLSSGLPTHADPAGSRAGADRLLSAGAELLIAGPGGVDRSGDSSPRRLARPTIALLVGTVVLLASILVASLGGAAGLPVGGTAEALLDKLPFVDLHTGLGPLQQSVLDQIRLPRVVLATLVGALLAQAGAAYQGVFRNPLSDSGTIGASAGAGMAATLVIVFGGGPEHTVAGIGAVPLAAFVGALGGVLTSYVLGTLVGRGGTAALILAGVAVSSFAGAVQAFVMQRSTTDVRQVYSWLFGSFAAADWSLVRLALPYAVISVLIVTVHARHLDVLALGDDEAATLGLNPVRTRLIVLAAASLATATAVAVSGIIGFVGLVVPHVVRRVAGPGHRLLLPMSLLVGGAFLVLADLLARTVLAPAELPIGVVTSFVGAPFFLVILRATRERDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R5</accession>
    <name>C7Q3R5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797397.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8860"/>
    <dbReference type="MEROPS" id="S01.513"/>
    <dbReference type="EnsemblBacteria" id="ACU77673">
        <property type="protein sequence ID" value="ACU77673"/>
        <property type="gene ID" value="Caci_8860"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8860"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043139_0_0_11"/>
    <dbReference type="OMA" id="YRQGFVV"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="40874" checksum="44B7BB77F617948C" modified="2009-10-13" version="1" precursor="true">MDILDILLLLVVAAFAVSGYRQGFVVGVVSFAGFLGGLALGFVIVPTFLDRSSASLLASVIALCAVLALAVVGQVLGSMLGAKLREAITWQPAQMVDAVSGAVVSVIAVLMVAWFLGLALFTSSVPTISDQVRSSSILKGMTQVLPQGANQWFSSFSNVLNRNGFPQVFAPFQAEDPANVPPPDPALLNSPVIAADRASIVKIRGQAPSCGKDIEGSGFVYASGKVMTNAHVVGGTRSLVVRQSNGKQYAATVVLFDPKRDIAVLDVPSLKAPQLNFDLGGKANDSSLVVGYPEDGPFTVDAARIREQITATGADIYSNGNVRRQVFALYAQVQQGNSGGPLLSTDGRVLGVVFAKSLEDKNTGYALTAQEVSSDAQAGAATDVPVNTQACAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U5</accession>
    <name>C7Q3U5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797427.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8890"/>
    <dbReference type="EnsemblBacteria" id="ACU77703">
        <property type="protein sequence ID" value="ACU77703"/>
        <property type="gene ID" value="Caci_8890"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8890"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_1_0_11"/>
    <dbReference type="OMA" id="HAWDIAV"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="20593" checksum="B737E5FE3485D533" modified="2009-10-13" version="1">MTSTGFAALDASHHALRTVVGSLAAGDLGRPTPCTDWTVTQVLRHAAGDQLGFASFLDGGSGPEENPFTPSATPPQDPKAYVEQAVTRSAAAWSAVDPDTEEVAVPVPPNKLSARVGAGACALDAAVHAWDIAMAVGAPSPLTPELSAELLDVARQIVEPLRQYGAYATALTPQPGDDAEAELLRYLGRDPRWTAVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W4</accession>
    <name>C7Q3W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797446.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8909"/>
    <dbReference type="EnsemblBacteria" id="ACU77722">
        <property type="protein sequence ID" value="ACU77722"/>
        <property type="gene ID" value="Caci_8909"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8909"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059078_0_0_11"/>
    <dbReference type="OMA" id="DTWFFVA"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039121">
        <property type="entry name" value="NUDT19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318">
        <property type="entry name" value="PTHR12318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="41"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31644" checksum="F060FA2890FCF376" modified="2009-10-13" version="1">MSQQGGEYIVPAGSRLSAHVPEGWEQQIAAYERGEFTAVPPKHAATVVLLRDREDGPPDVYLLKRAASMSFAGGFYAFPGGRVDPRDADAEIGWAGPSAADWARRFGSDEAEARALLCAAVRETFEESGVLFAGPDEHSVVADTTAEGWEADRRALVSRETSLAGFLAKRSLVLRTDLLGGWSRWITPEFEPRRYDTAFFVAALPAGQLTRDVSGETESTTWMPPRQAIDDHIAGRALMLPPTVTTLREVHSFNTAAEAVRAAATRPLTPIMATVRRHDDGSWHLEWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q438</accession>
    <name>C7Q438_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ordered locus">Caci_0966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785192.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0966"/>
    <dbReference type="EnsemblBacteria" id="ACU69898">
        <property type="protein sequence ID" value="ACU69898"/>
        <property type="gene ID" value="Caci_0966"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0966"/>
    <dbReference type="eggNOG" id="COG0101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_0_2_11"/>
    <dbReference type="OMA" id="FLYGMVR"/>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="155"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="30935" checksum="617A4DE0865F7FFA" modified="2009-10-13" version="1">MSTEPAPGHVRVRLDLAYDGTHFSGWAIQPKRRTVCGELTSALSTVLRQDVTLVVAGRTDAGVHASGQVAHLDVPLELWAEHEERLLRRLAAVLPGDVRVWSAVPAPVGFDARFAAMGRRYAYRVTDAAYGPHPLRRNDVTWHPRTLDPALMNEAAAALLGEHDFASFCKKREGATTIRCLTRLEWTREAPTSLTPVGLLVADVRADAFCHSMVRSLVGALLAVGEGRRPVGDPGRILAEEVRSPEVKVAPPQGLTLEEVVYPADAELAGQQLKTRRIRVLGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4N6</accession>
    <name>C7Q4N6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787298.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3096"/>
    <dbReference type="EnsemblBacteria" id="ACU72005">
        <property type="protein sequence ID" value="ACU72005"/>
        <property type="gene ID" value="Caci_3096"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3096"/>
    <dbReference type="eggNOG" id="COG3450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147448_0_0_11"/>
    <dbReference type="OMA" id="IWQITPG"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="1">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="12645" checksum="F2A897C3BE15656C" modified="2009-10-13" version="1">MSEDRTTVLGFALPVADAVLEPVALDASQVVAGAPEVSELVLSESADGRVVRGIWQMTPGVVTDTEADELFVVLAGRATVEFEDGAVLHVGPGDVAVLTEGAKTRWTVHETLRKVYQASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4P9</accession>
    <name>C7Q4P9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ordered locus">Caci_3109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787311.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3109"/>
    <dbReference type="EnsemblBacteria" id="ACU72018">
        <property type="protein sequence ID" value="ACU72018"/>
        <property type="gene ID" value="Caci_3109"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3109"/>
    <dbReference type="eggNOG" id="COG0054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089358_1_2_11"/>
    <dbReference type="OMA" id="CQGVTQG"/>
    <dbReference type="OrthoDB" id="1680292at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="161" mass="16350" checksum="68A86B6EFE04866E" modified="2009-10-13" version="1">MSGAGAPAISIEGGADLKVAVVAAQWHTQVMDGLVAGAEKALAEIGAEHDLFRAPGSFELPVLAKALAEAGSGYDAVVALGVVIRGGTPHFEYVCAAATDGLNRVALDTGTPIGFGLLTCDTEQQALDRAGLPGSREDKGREAVEAAVATALVLKKIEAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Q3</accession>
    <name>C7Q4Q3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3113"/>
    <dbReference type="EnsemblBacteria" id="ACU72022">
        <property type="protein sequence ID" value="ACU72022"/>
        <property type="gene ID" value="Caci_3113"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3113"/>
    <dbReference type="eggNOG" id="ENOG50331K6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110740_2_1_11"/>
    <dbReference type="OMA" id="TFRPTRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019692">
        <property type="entry name" value="DUF2581"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10756">
        <property type="entry name" value="bPH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="19637" checksum="8DC85F30BEF938F1" modified="2009-10-13" version="1">MERTSVQVTDNHDHDRQTPGPLDPYNLPVPEHVPPLPVTFRPQRTRIAVAAVSTALIVTLVVVSLILPDTGSTAWSVPERVGFAAIGPLISAGLYLLARPKIVADETGLTVVNTVRTQHLEWAQIVRVNLRPGDPWVLLDLDDGEVLPAMGIQASGGKASRRAAGELRALVDEHTRTERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q523</accession>
    <name>C7Q523_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5112"/>
    <dbReference type="EnsemblBacteria" id="ACU73971">
        <property type="protein sequence ID" value="ACU73971"/>
        <property type="gene ID" value="Caci_5112"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5112"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3832">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094111_0_0_11"/>
    <dbReference type="OMA" id="SKYAEPW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="29543" checksum="41D00686779720DD" modified="2009-10-13" version="1">MVSYCGAMDPVFKALADPTRRALLDELFARDGQTLAALTAQHDMTRIAVAKHLKILEEAGLVVARRRGREKLHFLNAVPIRLVHDRWVGKYTEQWAAGLVGLKRELEEEMERVFEIYIRTTPERLWEAITDPEIRTKYHFGLAVESDWSPGSDYRQSHPDGGRPIIEGVNLVVEPPHRLVQSMRALWGPDAEAAGTTRVTWEIEPVGDSCRLTVVHDQLPADVPPEIYGGWPMVLSGLKTWLETGEPLTTPGSLMYTPTNDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q548</accession>
    <name>C7Q548_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPK2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6987</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6987"/>
    <dbReference type="EnsemblBacteria" id="ACU75817">
        <property type="protein sequence ID" value="ACU75817"/>
        <property type="gene ID" value="Caci_6987"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6987"/>
    <dbReference type="eggNOG" id="COG2326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048699_2_2_11"/>
    <dbReference type="OMA" id="ESTQWYY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006793">
        <property type="term" value="P:phosphorus metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022486">
        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03707">
        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="66"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="37905" checksum="0831323007161CDF" modified="2009-10-13" version="1">MPSAATDEPDDRNDPDDRERAWTLADVTDIGGLRIEQADDDDPILIGADGVPIDTWRQDYPYRERLDRTRYEHDKRLLQIELLKLQNWIKDTGGRLVILFEGRDAAGKGGTIKRFTEHLNPRGARVVALEKPTERERTQWYFQRYVTHLPAAGEIVMFDRSWYNRAGVERVMGFCDPAEYLEFMRQAPEFERMLVRDGITLVKFWFSVSQAEQRTRFLIRQVDPVRQWKLSPMDLASLERWQLYTDAKEAMFFYTDTADAPWTVIKSNDKKRARLAAMRHVLSLFPYANKDLEIAQLPDPEVLGSAALLAERSDADPQRVLPRLSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5U8</accession>
    <name>C7Q5U8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-peptide hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acylaminoacyl-peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1119"/>
    <dbReference type="EnsemblBacteria" id="ACU70045">
        <property type="protein sequence ID" value="ACU70045"/>
        <property type="gene ID" value="Caci_1119"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1119"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_1_0_11"/>
    <dbReference type="OMA" id="DENHWIM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0007">Acetylation</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="7">
        <location>
            <begin position="474"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="688" mass="74207" checksum="1C30A6EEEA1B31FA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q653</accession>
    <name>C7Q653_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EccB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787352.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3150"/>
    <dbReference type="EnsemblBacteria" id="ACU72059">
        <property type="protein sequence ID" value="ACU72059"/>
        <property type="gene ID" value="Caci_3150"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3150"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_551923_0_0_11"/>
    <dbReference type="OMA" id="WTVCDAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007795">
        <property type="entry name" value="T7SS_EccB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044857">
        <property type="entry name" value="T7SS_EccB_R1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042485">
        <property type="entry name" value="T7SS_EccB_R3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40765">
        <property type="entry name" value="PTHR40765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05108">
        <property type="entry name" value="T7SS_ESX1_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03919">
        <property type="entry name" value="T7SS_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="313"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="49031" checksum="19A633E554790E09" modified="2009-10-13" version="1">MWTERDQIQAYQFLRRRLVSALVTSDPNHPTSPHRRLVMGTVLGTVATMLTAAGFGISGMMAPSPPPDWQHTGLVILDSDGGGRYVLDNTGVLHPVTNLASARLLANGVKTVSVTTKLLGGTPRGATLGIANAPDMLPDPAGVITAPAPVACSRATSDIPKQTGPAGALLLAHTGDATASLDGMVSLPEGRALVVQTPKGDRYLITDGLKYKLADNNVMTALGYQASATLPVAASWLTTLPSGRDLALTAVPGAGGPGPRVGAVKRKVGEVLTVDNAVAGKTLYYLVLSGGLEPIPQIQAALIVADGANAAAYTDGPQQPRPVSVSDATAAPSAPAGEDTKGYPAGVPGPVTGLGASTVVCATGDGAAPAQIAVGVAVPLPQGARTVPTGAPQGGTVADEVYLPPGTAALATIHTEPTTQNNGSQQNAPVYLITDAGTKYPLTDGTARSALGYGNAAPAVLPTTALAMLPTGPALDEADAQKPVVVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6C2</accession>
    <name>C7Q6C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Preprotein translocase subunit SecD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_3221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3221"/>
    <dbReference type="EnsemblBacteria" id="ACU72128">
        <property type="protein sequence ID" value="ACU72128"/>
        <property type="gene ID" value="Caci_3221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3221"/>
    <dbReference type="eggNOG" id="COG0342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_939057_0_0_11"/>
    <dbReference type="OMA" id="YSAPMIQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981436" evidence="9">
        <location>
            <begin position="28"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU72128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="29147" checksum="94965BDA49DBE7BD" modified="2009-10-13" version="1" precursor="true">MAAFTRRTQVVAALLGLAAATAVSGCASVGDVSVPPSTSSVSEPVVTVSPGQAVVNFTFAGSGTMAATPATLNQELAILKQRVSAQKLDGTTVAVAPDGRGIEVRGPAADKAELLMLGRAGVLEFRPVLTTDAGSAATAGSAPQSVSGAVWKQFTMLDCKNTQPTDAKPSAQIAACQSDGSQKFVLDAAAVSGAAVSAAGAASGPAGTWQVNVTLTSQGAAQFAQLTTRLAGTGGAVAITVDGIVYSAPMIQDPITDGAMLISGGFTQPTAQSLAAILQSGTLPVPLSMTSVGTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6N1</accession>
    <name>C7Q6N1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793795.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5207"/>
    <dbReference type="EnsemblBacteria" id="ACU74066">
        <property type="protein sequence ID" value="ACU74066"/>
        <property type="gene ID" value="Caci_5207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5207"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1021922_0_0_11"/>
    <dbReference type="OMA" id="REKVLWH"/>
    <dbReference type="OrthoDB" id="745068at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29608" checksum="8A9EB3594EF8BCAD" modified="2009-10-13" version="1">MFTAVTSECAPPVEYAVAVERFLVSAGLSTASQRIYRIALTTWSWMLVERESPVGAARRGAAAPVVPLGLLDSATAPSRLEAGFAAREAAVGARTANRELAILRSALSWWRAREWVTSDPTSAIRRRIATAPSIETLTDDQARAVLRLRAPLREQALWHAVYDSGGGIERILALDVPDLDPNGRRTRPRLPGEPLHWRAATGTLLALLAAGRPSGPLFLTDRRAPADTLARDRCAVTGRGRLSYRRAAELFTAATQGLDTAGRGWTLRQLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7S6</accession>
    <name>C7Q7S6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GP1 vegetative cell wall protein gp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3362"/>
    <dbReference type="EnsemblBacteria" id="ACU72269">
        <property type="protein sequence ID" value="ACU72269"/>
        <property type="gene ID" value="Caci_3362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3362"/>
    <dbReference type="HOGENOM" id="CLU_2354613_0_0_11"/>
    <dbReference type="OMA" id="MIRMSAL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="9729" checksum="3C3CC1A2CE1A6EB7" modified="2009-10-13" version="1">MTQTPTLTRTTRSPVADTIPPVPVPPGHPDGPEPQPPTPTPRPPGPGPEPTPPTPPTPGPPTPFPEPTPPSPQPVPGPDPLPDPAPSPIPTDTATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7W8</accession>
    <name>C7Q7W8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="7">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5276"/>
    <dbReference type="EnsemblBacteria" id="ACU74135">
        <property type="protein sequence ID" value="ACU74135"/>
        <property type="gene ID" value="Caci_5276"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5276"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_0_1_11"/>
    <dbReference type="OMA" id="LSLHREW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="35696" checksum="4D167A0433F18D55" modified="2009-10-13" version="1">MTVSTTAAAEQPLLSAGAPRALLDRVLRMRELAILVVLAVMLLATQIDNTSFLSKQGIKDLLLNATILVLVAVGEAVVVITGNVDLSVGSVLGVTAFAAGDLLQHGGNPVLAIGLAVVLGAGFGAVNGVLVGLGQVPSLVVTLGTLYIIRALDSIWVGSREVTASRLPSGYKSFGHNGLSAIPYLALLATVVLIAVGYFLRNYRSGRECYALGSHAQAAALAGVPVRRRVLAAFVLCGALAGLAGALYLARFGYADAGTGSGYELTVVSAVVVGGVGFTGGSGSVYGAALGALLLTSINSVLPAIGVSSVWVEAIDGVLLLLAISVDRIVALRIAGLLRSRARQARTITND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7X4</accession>
    <name>C7Q7X4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793870.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5282"/>
    <dbReference type="EnsemblBacteria" id="ACU74141">
        <property type="protein sequence ID" value="ACU74141"/>
        <property type="gene ID" value="Caci_5282"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5282"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_2_11"/>
    <dbReference type="OMA" id="WPLRTFA"/>
    <dbReference type="OrthoDB" id="816674at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="46298" checksum="B7F82F456381B762" modified="2009-10-13" version="1">MEPDVTAQDGCPRHRLDPLGGSPHERNARWLAEGPTVPVLMPGDVPGVLMLGHAALKDFLASPDVSKDPANFAEYQQGHVPDGWPLSGFTLPRTMLTADGADHRRLRAIVGNTFTRGRIKALKPAVEEMVDRLLEEMAQAAEESPDGVVDLRARFAAPLPLEVICELLGIPESARARLHEIASTVINTDVEPAQFIAASQEMVALLTAIVAARTEQPEQDLLSEMIARADDSLQLSTEEVIATLRSLFIAGHETTMGLLMNAVRALCAHREALEAVRQGKASWLAVAEETLRWDDPVSYFPLRYPTRDMDIAGHCIEAGTAVLAGYSAAGRDPAAYGPDADRFDVMREERVELLAFGYGPHYCPGAPLARLEAEIALARLFERFPDLDMAVSEDELQYSHTFVGNIVVALPVRLGADRERRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B2</accession>
    <name>C7Q8B2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ordered locus">Caci_7271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795828.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7271"/>
    <dbReference type="EnsemblBacteria" id="ACU76100">
        <property type="protein sequence ID" value="ACU76100"/>
        <property type="gene ID" value="Caci_7271"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7271"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_4_0_11"/>
    <dbReference type="OMA" id="GKDHTLH"/>
    <dbReference type="OrthoDB" id="1904463at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9084" checksum="9617C33C631044B1" modified="2009-10-13" version="1">MAHKKGASSSKNGRDSNAQRLGVKRFGGQNVNAGEIIIRQRGTHFHPGLNMGRGKDDTLFALAAGKVEFGTLRGRRVISIVPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8K5</accession>
    <name>C7Q8K5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785564.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1347"/>
    <dbReference type="EnsemblBacteria" id="ACU70270">
        <property type="protein sequence ID" value="ACU70270"/>
        <property type="gene ID" value="Caci_1347"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1347"/>
    <dbReference type="eggNOG" id="COG3305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093816_0_0_11"/>
    <dbReference type="OrthoDB" id="1438626at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021125">
        <property type="entry name" value="DUF2127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09900">
        <property type="entry name" value="DUF2127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29374" checksum="52FAECB961108FA6" modified="2009-10-13" version="1">MTDGRKRHRFDWSLLGCALSGHVLYAPTEPALRARLTAETAGGVTWRCLRCADFVPVGSAAPGAAAPTPPSGPAEDAPLVKRGAEMRDAVLLRFFAVERWIRALLLGAAAYVVHRFAGRQNDLRQAFDQAAPVVKQVFGKAGFDLQNSKTLELLQKAVDARPTTLAWIIAALAAYAVVEAVEGVGLWLLQRWGEYFAFVATGMFLPFEVYELTHRVSPLKLGTFLLNLALVLYLVWTKRLFGVRGGKRAYEAQRHAASLLEVERAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Q2</accession>
    <name>C7Q8Q2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SNARE associated Golgi protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785611.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1394"/>
    <dbReference type="EnsemblBacteria" id="ACU70317">
        <property type="protein sequence ID" value="ACU70317"/>
        <property type="gene ID" value="Caci_1394"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1394"/>
    <dbReference type="eggNOG" id="COG0586">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044208_6_3_11"/>
    <dbReference type="OMA" id="FMPLACG"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="26776" checksum="9895D6F53C15EE79" modified="2009-10-13" version="1">MGALLTWIADTLQKLPGPAALALVFLLPALEASVFLGFLIPGEIAVVIGGFLAFSGKVNLGVALAAAIAGAVIGDSIGYEVGKKWGDSLLTRLPERFVKPEHIEQGKQLINRLGGKAVFTGRFAAALRALVPGLCGVSRIPYRKFLFWNALGGIVWATGFTLLGYAAGNAWHKVEHYASIVSWVLLGLVVVGAAALFVVKRRKGAAEAVKGEVEDVVDDVKHAVAAVGEALDRAIDHEGERAGRQADDSAEAASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9H0</accession>
    <name>C7Q9H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5457"/>
    <dbReference type="EnsemblBacteria" id="ACU74316">
        <property type="protein sequence ID" value="ACU74316"/>
        <property type="gene ID" value="Caci_5457"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5457"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085054_1_0_11"/>
    <dbReference type="OMA" id="CDVSPKG"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024029">
        <property type="entry name" value="Pyridox_Oxase_FMN-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04025">
        <property type="entry name" value="PPOX_FMN_DR2398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="62"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="26427" checksum="ABEBF45398EF6F12" modified="2009-10-13" version="1">MTEAVVENTAPDAVAEPVSEPVIDPAPAEAAITTEAELRALLGEPMERAINKERVRLLPIDRRWLAASPLCFLSTCDDQGNCDVSPKGDPPGFVKVLDDTRLAIPERPGNRRADGYLNILRNPHVGLIFVVPGRNETLRINGRARLVREAAYFDDMVVKNHRPIMAIEVDIEQIFFHCPKAFLRSSLWKPPTWDPDQLPPHASIVKSVQWTRESLEELTEYYGASYEKSIYVTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9S6</accession>
    <name>C7Q9S6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795973.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7419"/>
    <dbReference type="EnsemblBacteria" id="ACU76245">
        <property type="protein sequence ID" value="ACU76245"/>
        <property type="gene ID" value="Caci_7419"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7419"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="RNLACGY"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="36384" checksum="9AD36005124DD0EF" modified="2009-10-13" version="1">MSGLSITGLRAGHGRTRVLDGVDLAVADGALACVLGPSGCGKSTLLRVIAGFHPAEQGQVALAGRVLDDGRVRLPAERRHIGYVPQDGALFPHLDVAGNIGFGLPRHRRRERVEELLDLVGLAGLDERHPHQLSGGQQQRVALARALAPEPELLLLDEPFAALDAALRTEVRTEVATTLRKAGTTAILVTHDQEEALTFADVVAVMREGRIAQTGTPTELYHQPADTGVARFLGEANLVPADIADGLARTAFGELALTDGSAADGPGVVLIRPRQIGLTAEPGVGTVRAEVVHCHFRGHDYRVEVAPDPGHGLPERLVAYSDAAPPTTGLVYLAAYGTAHRCPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z3</accession>
    <name>C7Q9Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)</text>
            <dbReference type="Rhea" id="RHEA:39663"/>
            <dbReference type="Rhea" id="RHEA-COMP:12939"/>
            <dbReference type="Rhea" id="RHEA-COMP:14378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:133980"/>
            <dbReference type="ChEBI" id="CHEBI:139511"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the F420H(2)-dependent quinone reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785685.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1468"/>
    <dbReference type="EnsemblBacteria" id="ACU70391">
        <property type="protein sequence ID" value="ACU70391"/>
        <property type="gene ID" value="Caci_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1468"/>
    <dbReference type="eggNOG" id="ENOG50334GQ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120846_0_0_11"/>
    <dbReference type="OMA" id="HAFANFH"/>
    <dbReference type="OrthoDB" id="1424867at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004378">
        <property type="entry name" value="F420H2_quin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04075">
        <property type="entry name" value="F420H2_quin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17547" checksum="BCC56D3B1E9D4672" modified="2009-10-13" version="1">MGTETKPAGRPAGRAQKLRVQGLVNAISRAALSTPGVAKGIGQNLILLYVYGRKSGKRYAIPIAYMAHDGKILIGTQFGWSRNLRTGDPIQVRYKGKLRSADVEVVTDPDRVAELYTVMCRKNHAFANFHAIGFDSSGEPDADAVRAAVEQGARAILLTPQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAU8</accession>
    <name>C7QAU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794150.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5562"/>
    <dbReference type="EnsemblBacteria" id="ACU74421">
        <property type="protein sequence ID" value="ACU74421"/>
        <property type="gene ID" value="Caci_5562"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5562"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="MSRTSIE"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="36"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="49711" checksum="64D43133C83F9842" modified="2009-10-13" version="1">MSQTDQIADSPPSLPDAVVVPGQRLGGSRAGNKTALLVIACVAQFMVVLDVSIVNVALPAMRGALDLSPTGVQWVVNAYALGFAGLLLFGGRAADLFGAKPVFLTGLVGFTAASLAGGMADTGGLLIAARSVQGLAGAVLAPATMTLIMTTFTDPRERTKALGAWSATMAAGGAMGAVVGGMLTQWVSWRWVLFVNVPIGVALILAAVPLIARTRGRGATLRTLDLPGAITVTLGLTGIVYGVVTTDTHSWGSGAVLAPMVAGAVLLALFVLLEARSKHALVPLRVFRNRSLAVADVAALLIGAGMFAMWFYVSLYLQQVLGFDALQAGFAFVPGSAMIVLGTMLATRALAKIGPRPLLLAGPLVAAVGLAWLSRFPAGGSYTADVLGPLMLLTFGMGLAMTPLAVAGTAGMPRHEAGLASGLINTSRQVGGAIGLAALSTISAHIAAHHGGSLKEATAAGYSGAMVGAAIVVAAAGVVAALLPRRGSEPVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB77</accession>
    <name>C7QB77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7543"/>
    <dbReference type="EnsemblBacteria" id="ACU76368">
        <property type="protein sequence ID" value="ACU76368"/>
        <property type="gene ID" value="Caci_7543"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7543"/>
    <dbReference type="eggNOG" id="ENOG5031WEA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_661726_0_0_11"/>
    <dbReference type="OMA" id="HLTHIPR"/>
    <dbReference type="OrthoDB" id="1581355at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="53945" checksum="DA6259F715DE8F7C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB78</accession>
    <name>C7QB78_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ordered locus">Caci_7544</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7544"/>
    <dbReference type="EnsemblBacteria" id="ACU76369">
        <property type="protein sequence ID" value="ACU76369"/>
        <property type="gene ID" value="Caci_7544"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7544"/>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060296_1_1_11"/>
    <dbReference type="OMA" id="WEFLATG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU76369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="36526" checksum="21D897B40F5F4925" modified="2009-10-13" version="1">MLLLCPTFTVCFPELPDAPRILRQTASIFRQGYELSGLNYLEACTIGLVQGVTELFPISSLGHSIILPAFIGGSWKADLDMTAKDSPYLAFLVLAHVATALALVAFFWRDWVRIIRALFTSVKDRSVETADQRLAWLLVVGTIPVGLIGIVADKELRTHLGKPIPAAIFLLINGFVIFLADSMLKSSSKGRHADDGTTPATHGESTEIAADRRLARLGWKSAAGIGGAQAFALLPGISRSGITMVAGLARGLKTEDAARFAFLLATPVILAAGVYKAPELAKPANHSILGPAVAGSVLAGIAAYISVRFLTKYFENRDLKPFGVYCVIAGIVSLVWFSVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBD5</accession>
    <name>C7QBD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1591"/>
    <dbReference type="EnsemblBacteria" id="ACU70512">
        <property type="protein sequence ID" value="ACU70512"/>
        <property type="gene ID" value="Caci_1591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1591"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_7_4_11"/>
    <dbReference type="OMA" id="VWYLLFD"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="44"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24125" checksum="A10302E6DDC50F94" modified="2009-10-13" version="1">MSGRIKHPVFARIYARYAGPSLEKAGIGVHRDRLLADLSGDVIEVGAGNGLNFPRYPHAVDRVVAVEPEPDLRALAERAARSAPVPVQVVEGRAEALPFPDGSFDAAVACLMLCSVADQGIALTEIARVLRPGGTLHFFEHVQAGTAGMRRVQRALDATVWPLFAGGCHTARDTAAAIAAAGFTVTELDCFEFPESRIPLPIQTHILGTATKPSAAPSPSSSPTRSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE1</accession>
    <name>C7QBE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1597"/>
    <dbReference type="EnsemblBacteria" id="ACU70518">
        <property type="protein sequence ID" value="ACU70518"/>
        <property type="gene ID" value="Caci_1597"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1597"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_665043_0_0_11"/>
    <dbReference type="OMA" id="IMEAYEY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981526" evidence="2">
        <location>
            <begin position="18"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="456" mass="49054" checksum="49338F91F5B3E6A8" modified="2009-10-13" version="1" precursor="true">MARSTSLQSVRCRRALAALAAVPLAVGLAACGSSSGSGSGSSQTLTIAMWTNPAAVAQTQKVDAEFEKAHPGVKVKLQTAPTAANAWPTLWQSLVSAKSVDVLAQFPPTPHAYPPASTGIVPQGTPALIQSGQFVDLTNQPFMKRFDPAAQKYAMGYNNGTYGVMTAEYVNNSGMFYKKDLLTKYGLSVPTTYSEFIKDLDVLKSKGVTPLYVAGKDGYQSIAWFGIMNQLLMQGKQSTDAPAVWEKRAQDFWDGTQSWTDPVYADTANRYEKVLSYMEPNAAGVPAQSAPGVWAAKTNDFPFFFDGSYDGNTIAQSNPSLNFGFMALPGADDAAANRAVLAPDLSWVVPTWSKHQQLAMEWLDMFTSPDNYAAWLKATGSISTEPAVPTPSLSWTDWLSTHASQGFVNAEQPWTSTKFPTAAGDQDRTKMQPFGSQTPAQALKESADAYKSAAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBL6</accession>
    <name>C7QBL6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1672"/>
    <dbReference type="EnsemblBacteria" id="ACU70593">
        <property type="protein sequence ID" value="ACU70593"/>
        <property type="gene ID" value="Caci_1672"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1672"/>
    <dbReference type="eggNOG" id="COG4636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076312_4_0_11"/>
    <dbReference type="OMA" id="LPEYMTW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="54"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="26835" checksum="7190D77E03F57851" modified="2009-10-13" version="1">MTVAMNDEAPPSPPAAELEASPELWSAFALVEWAGLLDGVTFEMWKHIPEEVCRDHELDNGRLIRRQSGSPGHQYLSLQLAMALQTAAKRAVQEGAFPCLKVAQDLDTRLWEVPKSTVRRPDVLVHRCLEESDEDLWATHVVLAVEIVSPTSRATDTGQDNPDAGFESKMTQYARAGIKHYWIVRLKADDSAVESIEEWRLAERLGRYTLVAVWSAGVSRDAVSTEYPFGIEISWSDLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBN5</accession>
    <name>C7QBN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785906.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1691"/>
    <dbReference type="EnsemblBacteria" id="ACU70612">
        <property type="protein sequence ID" value="ACU70612"/>
        <property type="gene ID" value="Caci_1691"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1691"/>
    <dbReference type="HOGENOM" id="CLU_191180_1_1_11"/>
    <dbReference type="OMA" id="GPECPAK"/>
    <dbReference type="OrthoDB" id="2077016at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="70" mass="7960" checksum="2A251BE96A92593C" modified="2009-10-13" version="1">MRWTKKGEPPEDDGWYYCVKHGAVEPAGACAAKDRLGPYQTREQAEHALQRVQERNEAWRKADEAAEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBN6</accession>
    <name>C7QBN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LamG domain protein jellyroll fold domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1692"/>
    <dbReference type="EnsemblBacteria" id="ACU70613">
        <property type="protein sequence ID" value="ACU70613"/>
        <property type="gene ID" value="Caci_1692"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1692"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520425_0_0_11"/>
    <dbReference type="OMA" id="SWHAAPR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="374"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="523" mass="51230" checksum="BF5C8CEBC5D490F6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBQ3</accession>
    <name>C7QBQ3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ATP:glutamine synthetase adenylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">ATase</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl-L-tyrosine phosphorylase</fullName>
                <ecNumber evidence="3">2.7.7.89</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl removase</fullName>
                <shortName evidence="3">AR</shortName>
                <shortName evidence="3">AT-N</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl transferase</fullName>
                <ecNumber evidence="3">2.7.7.42</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl transferase</fullName>
                <shortName evidence="3">AT</shortName>
                <shortName evidence="3">AT-C</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">glnE</name>
        <name evidence="7" type="ordered locus">Caci_1709</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18589"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP</text>
            <dbReference type="Rhea" id="RHEA:43716"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.7.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GlnE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.89" evidence="3"/>
    <dbReference type="EC" id="2.7.7.42" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785924.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1709"/>
    <dbReference type="EnsemblBacteria" id="ACU70630">
        <property type="protein sequence ID" value="ACU70630"/>
        <property type="gene ID" value="Caci_1709"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1709"/>
    <dbReference type="eggNOG" id="COG1391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006233_1_0_11"/>
    <dbReference type="OMA" id="EFMVQYA"/>
    <dbReference type="OrthoDB" id="427701at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047388">
        <property type="term" value="F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000820">
        <property type="term" value="P:regulation of glutamine family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00802">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="5">
        <location>
            <begin position="93"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="6">
        <location>
            <begin position="361"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="5">
        <location>
            <begin position="612"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="5">
        <location>
            <begin position="810"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="6">
        <location>
            <begin position="919"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl removase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl transferase" evidence="3">
        <location>
            <begin position="513"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="757"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="772"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1072" mass="114954" checksum="C6E16949E0E6A8EC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBQ9</accession>
    <name>C7QBQ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785930.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1715"/>
    <dbReference type="CAZy" id="GH38">
        <property type="family name" value="Glycoside Hydrolase Family 38"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70636">
        <property type="protein sequence ID" value="ACU70636"/>
        <property type="gene ID" value="Caci_1715"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1715"/>
    <dbReference type="eggNOG" id="COG0383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003442_2_1_11"/>
    <dbReference type="OMA" id="VVTRPNK"/>
    <dbReference type="OrthoDB" id="299689at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_38N" evidence="3">
        <location>
            <begin position="5"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_38C" evidence="4">
        <location>
            <begin position="655"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1002" mass="105250" checksum="33BD892D71AA41CC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH2</accession>
    <name>C7QCH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LPPG domain protein containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796160.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7611"/>
    <dbReference type="EnsemblBacteria" id="ACU76435">
        <property type="protein sequence ID" value="ACU76435"/>
        <property type="gene ID" value="Caci_7611"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7611"/>
    <dbReference type="eggNOG" id="COG0391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055795_0_0_11"/>
    <dbReference type="OMA" id="DLDTVMY"/>
    <dbReference type="OrthoDB" id="1079756at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07186">
        <property type="entry name" value="CofD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01257">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010115">
        <property type="entry name" value="FbiA/CofD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43007">
        <property type="entry name" value="PTHR43007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01819">
        <property type="entry name" value="F420_cofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="33916" checksum="F23EA932665282AF" modified="2009-10-13" version="1" precursor="true">MHITALAGGVGGARFLRGLLAAAPDADVTVIGNVGDDMTMHGLRICPDLDTVMYTLGGGIHEGQGWGRVDETFGVAEELKAYGVGPDWFTLGDKDIATHLVRTQMLGAGYPLSAVTEALCTRWELPVRLLPSTDERVETHVVVDDPEAPGGRRAVHFQEYWVRMHAPDARAIVSVGVEDAKPAPGVLEAIAEADVIVLPPSNPVVSVGTILNIPGIRQAVAGATAPVVGLSPIVGGGPVRGMADKVLAAVGVDVTAAAVAKHYGPELLDGWLVDADADASAVAEVEAAGIACRAVPLMMSSAEATRAMARAALDLAAEIAASHGSARPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCN7</accession>
    <name>C7QCN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796225.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7676"/>
    <dbReference type="EnsemblBacteria" id="ACU76500">
        <property type="protein sequence ID" value="ACU76500"/>
        <property type="gene ID" value="Caci_7676"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7676"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_11"/>
    <dbReference type="OMA" id="AHYPNME"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28495" checksum="8C26126165647A73" modified="2009-10-13" version="1">MNATHSVSLPDGGRLAYRDEGSGPLVVLLHGGFLDHRQWNAQLQSLPADFRTVAPDARGHGDSTVAAAPFRHTDDVAALIRHFDAGPAILVGVSMGAATATDTALEHPELVRALVVSGAGTSEPEFADGWTARTLAAIWPPLSAGDVAGALKIWNSLTTGPHRDPADLDPAIPALIAEMTAKTWAKHTDTKDWSSHAENTWARAAHLSIPLLAVIGGADSDDHRHNAERLAAGVTGARTVTIADAAHYPNMEHPEEFDMILTEFIDTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ2</accession>
    <name>C7QCZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785996.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1781"/>
    <dbReference type="EnsemblBacteria" id="ACU70702">
        <property type="protein sequence ID" value="ACU70702"/>
        <property type="gene ID" value="Caci_1781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1781"/>
    <dbReference type="eggNOG" id="ENOG5031INW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021151_2_0_11"/>
    <dbReference type="OMA" id="QWDSWRR"/>
    <dbReference type="OrthoDB" id="1770401at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021421">
        <property type="entry name" value="DUF3071"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11268">
        <property type="entry name" value="DUF3071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="42279" checksum="815AEF4B0A4E92F3" modified="2009-10-13" version="1">MTELRVMAVTSDGQRLVLRSNDGQEFHLTIDERLRAAVRGDRARLGQIEIEAEGQLRPRDIQARIRAGATAQEVADACGISVERIRRFEGPILAERAFMAEKAQNTQVRRQGENHGQKLGEIVAERLAKRGAEDPAAVRWDSWRRDDGTWTVQAVYKISGETYEALWGFDPPRRLVTPEDDEARLLSSDAAAIAAAEPMFPFVAASVLSGGTVVPGPAPSSNGSSAGGSLVHLEARRRPAETSSNGSGGALERERERDRERERTAAERTASVERHPSSMPASAAASGAAAVNGTAGRQGVPGPSASPEEDFDFLDAAADARAAAPVAAVAGQSAGSAFDDAIFGPRTTTPHRERMVGTTDRQAEADGVRPGRRATVPSWDEIVFGSRRGKQKGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD90</accession>
    <name>C7QD90_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3781</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792412.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3781"/>
    <dbReference type="EnsemblBacteria" id="ACU72683">
        <property type="protein sequence ID" value="ACU72683"/>
        <property type="gene ID" value="Caci_3781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3781"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="QSIVTFP"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="259" mass="27629" checksum="C80F71E71052C630" modified="2009-10-13" version="1">MATDVGGLTTAPAGVAVRGLYRSFNRSGGVLNGLDLDIAPGEFVALIGRSGSGKTTLLRALAGLDRDVEGYGRITVPEQVSVVFQDSRLLPWKRLLANVTLGLEGRDAVERGLRALAEVGLAGREQAWPAELSGGQQQRAALARSLVREPRLLLADEPFGALDALTRAQMHRLLRKLCQAHQPAVLLVTHDVDEAIVLADRVILLDDGIVATDLRIDLEQRSAADPGFAVLRQRLLDALGATGEHLGSDFIAPGTRRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD93</accession>
    <name>C7QD93_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792415.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3784"/>
    <dbReference type="EnsemblBacteria" id="ACU72686">
        <property type="protein sequence ID" value="ACU72686"/>
        <property type="gene ID" value="Caci_3784"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3784"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="HIWDYNT"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="18"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="37084" checksum="4FE0C37A7AD953EE" modified="2009-10-13" version="1">MSIPLRPFGRTGVKVSALALGTMMFGPRGNPDHDDSIRIVHRALDAGINLVDTADVYSQGESETIVGKALAGRRDSVFLATKFHGRMGEDANRFGNSRRWIVKAVEESLARLQTDHIDLYQVHRPEDDTDIDETLGALSDLVHQGKIRYIGTSTFEPSGIVEAQWVAEKRGRERVVAEQPPYSVLARGIEREVLPVAQKYGLAVIPWSPLAGGWLTGKFRVGAAQPETSRGAQQGRFEIGDPANADKLQAVEALALLAEEAGISLVHLALAFVLEHPAVTAPIIGPRTFEQLEGQLDAASLRLAPDVLDEIDKIVPPGVTLSARDAGYNPPSVTDSARRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDC7</accession>
    <name>C7QDC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3819</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3819"/>
    <dbReference type="EnsemblBacteria" id="ACU72720">
        <property type="protein sequence ID" value="ACU72720"/>
        <property type="gene ID" value="Caci_3819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3819"/>
    <dbReference type="eggNOG" id="COG4209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_1_11"/>
    <dbReference type="OMA" id="IWQTAGW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="95"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="36286" checksum="2AB7244C6E19A4AD" modified="2009-10-13" version="1">MGIAGTVDPPPGRERARPLRPRRKTWRRALRRDWQLYSLAVLPVVFFVVFRYLPMIGNVIAFRRYVPGGSLFGEKWVGLRYFRMFMGDPEFWHVFGNTMILGGVTLLFTFPLPIVLALLLNEVRSAKLKRFVQSVSYLPHFLSIVVVAGLIMQLLSVNGAVNQGLRAVGHAPIPFLQQPEWFRTIYVSSEVWQGLGWGTILYLAALTTIDHQLYEQARIDGANRWRQTWHVTLPGIRPMMVTLLVLNIGTFMAVGFEKILLLYNPLTYSTADVIPTYLYRVGVVSGSFSYGAAIGLFESVIGLILVVAANQISRRAVGTGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDU4</accession>
    <name>C7QDU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M55 D-aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794447.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5860"/>
    <dbReference type="EnsemblBacteria" id="ACU74718">
        <property type="protein sequence ID" value="ACU74718"/>
        <property type="gene ID" value="Caci_5860"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5860"/>
    <dbReference type="eggNOG" id="COG2362">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086038_1_0_11"/>
    <dbReference type="OMA" id="FMGHEIE"/>
    <dbReference type="OrthoDB" id="1439650at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027476">
        <property type="entry name" value="DppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007035">
        <property type="entry name" value="Peptidase_M55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036177">
        <property type="entry name" value="Peptidase_M55_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04951">
        <property type="entry name" value="Peptidase_M55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015853">
        <property type="entry name" value="Pep_DppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63992">
        <property type="entry name" value="SSF63992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29809" checksum="C2FB3B7D8FC0A1EF" modified="2009-10-13" version="1">MRIFISADMEGITGLVDADDVQPGGRDYERGRLAMTGDVNAAVRGALRAGATEIVVNDAHGPMRNLMTDTLHPAARLIRGKPKTMGMIEGLTGAHDALICVGYHARAGAHGVLSHSFMGHEIEDMWLDDRATGEIGLVHAAAAALGVRLAALTGDDAACAEATAWDASIATAPVKYVRSRFAAELRPENEARAAIEDTILAVLNEMPADDGEHTSSDAVSDAESTLAVRWQSSAVAETLLGIPGVTAVDPRTVQAVGTPPDLFRQFGVWMRVASALTNQAPYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEC4</accession>
    <name>C7QEC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1895"/>
    <dbReference type="EnsemblBacteria" id="ACU70815">
        <property type="protein sequence ID" value="ACU70815"/>
        <property type="gene ID" value="Caci_1895"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1895"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="IREMRDY"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="32"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37134" checksum="464507CD2E15018A" modified="2009-10-13" version="1">MSCEAVRTRHYAAPPPTEIVEDMEPSTRETIIEARAVSFAYRAKSGPAKKPHVAVRDVDLRIRRGELYALLGTNGAGKTTTLEVLEGHRAATSGQVTVLGGAPSDRRHIRPRMGIMLQDSGLAAELSVRESVALAGAISGRRDDVGKVLERVGISHRGGTRVAQLSGGEKRRVDFAMAIWGGPELVFLDEPTTGLDPASREALWSVVEDLKADGATFVLTTHYLEEAEKHADRVGLMHAGSIRREGTVAELTEGGVSTIRFVPPGAVSDIPIPLARTENGLAVIETRQVQQDVTALMTWAAEHDHRLARFTVRESGLDDIFRSLRHEAPEAADPSSSYERTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEF4</accession>
    <name>C7QEF4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786138.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1925"/>
    <dbReference type="EnsemblBacteria" id="ACU70845">
        <property type="protein sequence ID" value="ACU70845"/>
        <property type="gene ID" value="Caci_1925"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1925"/>
    <dbReference type="HOGENOM" id="CLU_1666231_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="158" mass="16416" checksum="392252386FC3B87E" modified="2009-10-13" version="1" precursor="true">MVVTVIVVLIVLAALVAAYYFGPAGWRTSAAGTFGGFGTRVGKFIESGRADPRPGVGGAAATPVPPRFSEADRAYLDGVWKHVQSTFVSNPRVAVTLAHKTAEGFFAAHGVSTEGLPQGPDSADGDSEAGAAAGVEDTEAMRQRLLAIKTWSDREAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEJ1</accession>
    <name>C7QEJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1962</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1962"/>
    <dbReference type="EnsemblBacteria" id="ACU70882">
        <property type="protein sequence ID" value="ACU70882"/>
        <property type="gene ID" value="Caci_1962"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1962"/>
    <dbReference type="eggNOG" id="ENOG5033HT5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1420536_0_0_11"/>
    <dbReference type="OMA" id="ECGEIFD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21708" checksum="7F33049D1A8A77FF" modified="2009-10-13" version="1">MTTKAPFPEAATIVTVAAMANRSHLYAANTLPTGESRPATVAGISEHNWSIPLAHLLLVSFDTRVVPSMIWDQRIGVAGDYDRGAALLLDLLRVVGEEVEDEQDFVSVVATTKAQLDKQRAKYFLLEAGEILDMDEEPLETATDRLVAEHIPALAAHAEAAIAGENAEWLAIARGRWREHFYSFYNDTLYYSFETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF33</accession>
    <name>C7QF33_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein TetR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794520.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5933"/>
    <dbReference type="EnsemblBacteria" id="ACU74791">
        <property type="protein sequence ID" value="ACU74791"/>
        <property type="gene ID" value="Caci_5933"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5933"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_2_11"/>
    <dbReference type="OMA" id="MNTGRYP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27232" checksum="65768228F355704D" modified="2009-10-13" version="1">MAKTKSEGAPSAADGEIPATIWERLDAPRTARSTLTHDRIAEAAVALADAEGLEAVSMRKLAERLGVATMALYRYVDSKDELLELMTDAVSDPATLTADPEDWRAVFGEAAHRRRATALAHPWLPAAQSQVPATLTPSRNQVLERMLAALEPLPLTGDQKMQLIRALDAYARGAADGEVNQRMMLERRGYGADGDVRLLLRANMQWLLRSGRYPRFAALVTDGLAPVDAVREFELGLQAMLDGLAARFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD0</accession>
    <name>C7QFD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell divisionFtsK/SpoIIIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796432.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7884"/>
    <dbReference type="EnsemblBacteria" id="ACU76707">
        <property type="protein sequence ID" value="ACU76707"/>
        <property type="gene ID" value="Caci_7884"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7884"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003134_1_0_11"/>
    <dbReference type="OMA" id="WEWMKWL"/>
    <dbReference type="OrthoDB" id="7548at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023836">
        <property type="entry name" value="EccCa-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023837">
        <property type="entry name" value="EccCb-like_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03924">
        <property type="entry name" value="T7SS_EccC_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03925">
        <property type="entry name" value="T7SS_EccC_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="457"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="830"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="1088"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1310"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1313"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="480"/>
            <end position="487"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="848"/>
            <end position="855"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="1105"/>
            <end position="1112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1348" mass="143294" checksum="64E65624AE41CDCC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL2</accession>
    <name>C7QFL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7966</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796514.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7966"/>
    <dbReference type="EnsemblBacteria" id="ACU76789">
        <property type="protein sequence ID" value="ACU76789"/>
        <property type="gene ID" value="Caci_7966"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7966"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="TQKIGYY"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="26"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="50505" checksum="9F08A6991D262584" modified="2009-10-13" version="1">MSTASISTTPSTGKVVPKREPKPGLILATIVTCQLMLVLDATIVNIALPKIQTSLKFSDANLSWVLNAYTLAFGGLLLLGGRAGDILGRRRMFVSGVILFTVASFIGGLAVDSTMLLASRALQGVGAAMAGPSMLALIITTFPEGAPRVKAMSLFTAVSSAGGSVGLLLGGMLTTWGSWRLVMYINVPIGAVAAIAAARLLNESPRVQGKFDIPGAITSVTGMGSLVYGFINASEHGWSNPTTIGVFVAAVVLLSSFVFIESRVDFPVFPLRLLRDSTRARSYGSYVLLVGAMFSMFFFLPQFMQEVLAYSPMKAGLAFLPLTATLFAVSRFIPKLLPRFGPRPLIVTGTALIAGALFWLSQVSIHTGFVTGLLAPFLMFGLGGGIAFSPIALNIMNGLAPRDSGAGSGLMQACQQIGGALGIAVLVTIFTSSKKGSHDPNPAVNFTHGLGTGLTVGAGIAVAVCLISLTLKPKPAAPSAGPAPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR2</accession>
    <name>C7QFR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784296.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69001">
        <property type="protein sequence ID" value="ACU69001"/>
        <property type="gene ID" value="Caci_0046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0046"/>
    <dbReference type="HOGENOM" id="CLU_1303062_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22112" checksum="9D725CF2541B0277" modified="2009-10-13" version="1">MPFSHDEPASRVERVRCAVRDRTSGAAHTVSGAAGTAQSAAVTAAGVAQGTAHQVADRATVVGQQVADRATVVAHQVADRTTVAAAAMADRARPVAAEAASRGGAAWQVIRYGAPQPSPLARMATVIPLATVTTAARRSRAPLALMAIGAACAVGILWWRRSRTGPDSVWILDSDSDVEPVGRWQERDNRADADDSGMDTSRRDSPANRWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG76</accession>
    <name>C7QG76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792650.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4056"/>
    <dbReference type="EnsemblBacteria" id="ACU72921">
        <property type="protein sequence ID" value="ACU72921"/>
        <property type="gene ID" value="Caci_4056"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4056"/>
    <dbReference type="eggNOG" id="ENOG502ZHVA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_899223_0_0_11"/>
    <dbReference type="OrthoDB" id="2051245at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="32231" checksum="213C7CDD0463BFD0" modified="2009-10-13" version="1">MTISRERLHQATCALHDAAEQAHRTDGIATMAALFVPPEGPAHFYYFPEGLPAAEVLAAIVRDSGAAGIAVTGEVWESEPGIPGTILVDMAFDDMPLPANDPNATEAIFTTAAGLGDDGPIKLLRRTRIDRTGNGLHEAVDLKTGIRDDGLAALLAVALAAGNTPANAPTGNAAAPGEQHHCPSCGVCRGHLHTDACDIGWCAATGRQRDARCTVTRGCRTDPRLDCRTVWTGLHPGIAECRDFGWFAVPGPDGWTPAAPGTPGATEDLNRLIAEAVWDPHAQRYQAPGDTSPPDPGLPPGGDRIGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG0</accession>
    <name>C7QGG0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_4141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792734.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4141"/>
    <dbReference type="EnsemblBacteria" id="ACU73005">
        <property type="protein sequence ID" value="ACU73005"/>
        <property type="gene ID" value="Caci_4141"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4141"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_2_11"/>
    <dbReference type="OMA" id="NAKVLAW"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="210"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU73005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="34983" checksum="F50DF0BBBDD6F7BF" modified="2009-10-13" version="1">MTRIAINGFGRIGRNVLRALLERGSDLEVAAVNDLTEPAALARLLAFDTTAGRLGRPVRADGDTLVVDGRRIAVLAERDPGQLPWAELGVDIVLESTGRFTAAKAAHAHLDAGARKVLVSAPSDGADVTLAYGVNTEAYDPVAHTIVSNASCTTNALAPLAAVLDDLAGIEHAFMTTVHAYTQEQNLQDGPHRDPRRARAAAVNIVPTTTGAAKAIGLVLPRLDGKLSGDSIRVPVPVGSIVELNTTVSRDVTREDVLAAYRTAAKGALAGILEYSQDPLVSSDIVGNPASAIFDSALTRVEGRHVKVVAWYDNEYGFSNRVVDTLELLATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGI3</accession>
    <name>C7QGI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6006"/>
    <dbReference type="EnsemblBacteria" id="ACU74863">
        <property type="protein sequence ID" value="ACU74863"/>
        <property type="gene ID" value="Caci_6006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6006"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_21_1_11"/>
    <dbReference type="OMA" id="AYTLQIV"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="36"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="169"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="32450" checksum="EE852C36F9DB3086" modified="2009-10-13" version="1">MITDAPTPESALSAPPPPADLYAVPRRSGMLATAGLLATTAVWGSTFLVVKDAIVSVPVLDFLGLRFAVACVAMLAVRPRALAALGRSGWRHGVLLGLVLAGGYTAQTFGLQTASASVSGFITGLFVVFTPLIGAVVLRRRVPPTVWVAVVLATVGLGLIALHGLSIGRGELLTVGGAFFFALHIVGLGEWSHRHDAYALAVVQIGTVAAVSLLLALAGDTEHGRHTLTLPPDTAGWAAVGVTALLGTAAGFFLQTWSQARMPATRAAVVLTMEPVFAGVTGVLAGETLAVRGWIGAALVLAAMYAVELGPRRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL5</accession>
    <name>C7QGL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cob(I)alamin adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794624.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6038"/>
    <dbReference type="EnsemblBacteria" id="ACU74895">
        <property type="protein sequence ID" value="ACU74895"/>
        <property type="gene ID" value="Caci_6038"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6038"/>
    <dbReference type="eggNOG" id="COG2109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088595_0_1_11"/>
    <dbReference type="OMA" id="HAMGEGF"/>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22940" checksum="E6EBF07511E25423" modified="2009-10-13" version="1">MPQGQPTHVPDDGLTTRQRRNRPLTIVHTGPGKGKSTAAFGLALRGWNQGWPIGVFQFVKSAKWRIGEESALKALGELHERTGQGGAVDWHKMGEGWSWIQRDLHSDPELQADNARAGWERIKADLAAETYRLYVLDEFTYPMKWGWVDVEDVVQTLAERPGAQHVVITGRDAAPALLEAADLVTEMTKVKHPMDAGQKGQKGIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH21</accession>
    <name>C7QH21_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuD</name>
        <name evidence="12" type="ordered locus">Caci_8048</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796596.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8048"/>
    <dbReference type="EnsemblBacteria" id="ACU76871">
        <property type="protein sequence ID" value="ACU76871"/>
        <property type="gene ID" value="Caci_8048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8048"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_0_1_11"/>
    <dbReference type="OMA" id="AFTTHTG"/>
    <dbReference type="OrthoDB" id="1384217at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU76871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="22709" checksum="315A783FA1F693AC" modified="2009-10-13" version="1">MEKFTTHTGRALPLRRSNVDTDQIIPAVYLKRITRTGFEDGLFAAWRADPEFILNQEQYQDVSVLVAGPDFGTGSSREHAVWALKDYGFKVVLSARFADIFRGNSAKDGLLTAVLKQEDIEILWKLVEENPELEVTVDLQAREVRVEGHVFTFEVDDYTRWRLLEGLDDISLTLRHAEEIDVFEEERPGFKPKTLPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHG2</accession>
    <name>C7QHG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784396.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0146"/>
    <dbReference type="EnsemblBacteria" id="ACU69101">
        <property type="protein sequence ID" value="ACU69101"/>
        <property type="gene ID" value="Caci_0146"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0146"/>
    <dbReference type="HOGENOM" id="CLU_849133_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="34204" checksum="F85683A0F6AFD6D1" modified="2009-10-13" version="1">MTELDTREDDWARGVFDRARTGRHEPHWAPDAAGAARLSKRRQTRYRATGALAVMAVAGLSATAFTALGGNVFHARDTVSPGSSGPILWPGLDLTKYLDVHESYMVAAGHQYEANRMPAVSLATTSTVLQRLDPGLKHVRTVSGHQDLDITPTPPGVTTMAVQADGIWSPNGDLSTFPPASSNFSPVTTPFGYVSIATMGPHVAQDANMENKPCGLGTLVTSTRIPAPTAWSPCVRSHQSDGSDILVTHAVNLPAGAVTVAARVFPDTSTVQVTASSVFGLQEGPAAGSSTPATPAKFDAGPPLNPVPWTDDSLAQVLTGPDVKGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHK9</accession>
    <name>C7QHK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2115"/>
    <dbReference type="EnsemblBacteria" id="ACU71034">
        <property type="protein sequence ID" value="ACU71034"/>
        <property type="gene ID" value="Caci_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2115"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068650_0_0_11"/>
    <dbReference type="OMA" id="HTHLEVE"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036693">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="29048" checksum="8BDB08E4702CE893" modified="2009-10-13" version="1">MTIALPGPAPRPRPLPADEPLSPEDYRRVVGVVEAVDHAGDLAEFRERLVTALRSWFGYSGVTVLHGETAADAVDRGCGVLAGYSAEFLATYAAQGWEREDPFRDEGFLQRLAEAGVVRLTDISEGARFREEFLVPRGIADKAAMLIDAAPSGVLWVGLAVPDGVGRVSDRDLAVLRVLRRHLTPLAVEQLARNRSREASRGDWDLTPREWDVADLAAQGLTNRQIAARLFIGVDTVKKHLTRVLAATSCGSRTQLALLFTTRGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHT9</accession>
    <name>C7QHT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786407.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71114">
        <property type="protein sequence ID" value="ACU71114"/>
        <property type="gene ID" value="Caci_2195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2195"/>
    <dbReference type="HOGENOM" id="CLU_2664353_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980992" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="7457" checksum="42C46187FB5769F4" modified="2009-10-13" version="1" precursor="true">MKSRLTKLTATAGATVLLAGLGAVAATSASAATAPAAAVTHTAAVPMSTPIAAHHPGWRPWCEIDLLGPVLCINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHZ2</accession>
    <name>C7QHZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4173"/>
    <dbReference type="EnsemblBacteria" id="ACU73037">
        <property type="protein sequence ID" value="ACU73037"/>
        <property type="gene ID" value="Caci_4173"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4173"/>
    <dbReference type="eggNOG" id="COG3861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324449_0_0_11"/>
    <dbReference type="OrthoDB" id="1779215at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="25413" checksum="79EBF3512A33647D" modified="2009-10-13" version="1">MQATLEYVIGSRVRCAGDECGEVEFVVVDPVADKLTHLVVRPDDGGQARLVPVHIAVPGPEGVDLNCTRARFEEFEPALQTYFMPDIERVGPAREERVLAWPLYGLVMTPTALTGFVPGVDPQLAATTVEHIPAGEVSVRRGERVHADGGGEVGRVQGLVVAPPDSEVTHVLLDEGHLWGRKRVAIPIQDVLGIDAAGVSVGLTKEQIKELPPVDVDGLAAESGEDEGDGEGQQAPAQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI92</accession>
    <name>C7QI92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792866.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4273"/>
    <dbReference type="EnsemblBacteria" id="ACU73137">
        <property type="protein sequence ID" value="ACU73137"/>
        <property type="gene ID" value="Caci_4273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4273"/>
    <dbReference type="eggNOG" id="COG4954">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121942_1_0_11"/>
    <dbReference type="OMA" id="QSCRTYD"/>
    <dbReference type="OrthoDB" id="1746879at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018988">
        <property type="entry name" value="DUF2000"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017021">
        <property type="entry name" value="UCP033763"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09391">
        <property type="entry name" value="DUF2000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033736">
        <property type="entry name" value="UCP033763"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15310" checksum="B9A876D9AC6D3C1C" modified="2009-10-13" version="1">MPLLDTTLPRFEKCAIVIDDALPTGLAMNAAAVLALSIGDAYGESALGPDVKDRDGQVHQAITEVPLPILKADAQVLHSIVTKALAEPDVFLVDFTSAAQAARDYGSYMQSMEVTGSQDHVYVGVAVVGAKKAVQRLSGSLPLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII4</accession>
    <name>C7QII4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794790.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6207"/>
    <dbReference type="EnsemblBacteria" id="ACU75061">
        <property type="protein sequence ID" value="ACU75061"/>
        <property type="gene ID" value="Caci_6207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6207"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_129_3_11"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="543"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="695"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="4">
        <location>
            <begin position="831"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1117" mass="118721" checksum="15435A04BAFC40C3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ02</accession>
    <name>C7QJ02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0189"/>
    <dbReference type="EnsemblBacteria" id="ACU69144">
        <property type="protein sequence ID" value="ACU69144"/>
        <property type="gene ID" value="Caci_0189"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0189"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_4_11"/>
    <dbReference type="OMA" id="ISKWLTH"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </location>
    </feature>
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    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="10"/>
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    </feature>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU69144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="42460" checksum="AD13F52B74CF5566" modified="2009-10-13" version="1">MDATDRLPSQVKALIVARAVNQLGGFSLAFLTVLLTRSFGTSLTTAGIVSAAFGLATIPSRLAGGRLADHWGRRRTIVAGLVALAVAQLGLAAAPDLITATICAVAMGLAFELFEPPSQATIADAVPPARRASAFELLTTAVAAGSLAAGVIADIVGRWSLRWLFVVDAGTGLACAAIVALALAPDAVRKPEHGAESDQPATSAISPWRDPALLIATVSGTVFALVSMLMLSALPLALGAVGLNPASAGLIMAASTGTLVLARPVLRRRWLAELPHSATFVLGYLLMAAGLCGYAVAHTLPALLVPTALYSLGNLLVLGRSFAVVSELAPASASARYLAVYGLSWGVATLLAPLVGTWLIGVSGAGLLWGVSAGVCGVMAVAQPWVVRRVRDSQRDLGVIHSTKAAVDRYDAVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ74</accession>
    <name>C7QJ74_CATAD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0263</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU69216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69216">
        <property type="protein sequence ID" value="ACU69216"/>
        <property type="gene ID" value="Caci_0263"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0263"/>
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            <begin position="6"/>
            <end position="23"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU69216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="40" mass="4410" checksum="DF10361642B093F1" modified="2009-10-13" version="1">MEVLIIFGGVYAAFLIGRVLQYLSDAKRVLGRGGDRNGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
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            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
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        <property type="gene ID" value="Caci_0277"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG0477">
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    </dbReference>
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    <dbReference type="OMA" id="FAYIGSM"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="180"/>
        </location>
    </feature>
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        <location>
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            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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            <end position="455"/>
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    </feature>
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        <location>
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            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="151"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="594" mass="60951" checksum="05389B74DC05C934" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJA6</accession>
    <name>C7QJA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ordered locus">Caci_0295</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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        </lineage>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0295"/>
    <dbReference type="EnsemblBacteria" id="ACU69248">
        <property type="protein sequence ID" value="ACU69248"/>
        <property type="gene ID" value="Caci_0295"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0295"/>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071263_0_0_11"/>
    <dbReference type="OrthoDB" id="1745973at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041629">
        <property type="entry name" value="SCP_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17844">
        <property type="entry name" value="SCP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="SCP_3" evidence="2">
        <location>
            <begin position="161"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="27697" checksum="961EFCF0A779B44B" modified="2009-10-13" version="1">MPKTRRPASAKVRQAVVNQWQAHVGYAAALTAEQLAAPSKLAGWDVKTLVGHVAFTVRTVVTRAAEPVAGDQAEVYDWLTATPTASAAVDAGTRELVEDGVVLADEVTEAEKLMERYGDEDLIAMRFGPMRFDDFLVSRIVEATVHADDLERSTGIEFPHDREALAITVRQLADAMAAKVPGNSVELRVPPFAAVQCVPGPRHTRGTPPNVVEMTPRTWIRLAAGRMTWDEAMDQALVSASGQRADLKEFLPLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG0</accession>
    <name>C7QJG0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rieske (2Fe-2S) domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786476.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2265"/>
    <dbReference type="EnsemblBacteria" id="ACU71183">
        <property type="protein sequence ID" value="ACU71183"/>
        <property type="gene ID" value="Caci_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2265"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_5_2_11"/>
    <dbReference type="OMA" id="TLECWLH"/>
    <dbReference type="OrthoDB" id="1681886at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="13"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12037" checksum="4F0583CBC97E3F0D" modified="2009-10-13" version="1">MSAQQNAATQNWVRVCGVSEVTPDQPKAVVAGDTPVAVVQHDGAFYAIHDVCSHANVALSEGEVVDCEIECWLHGSMFDLKTGKPSSLPATEPVPVYPVKIEGDDLYVAVKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK51</accession>
    <name>C7QK51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794854.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6271"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75125">
        <property type="protein sequence ID" value="ACU75125"/>
        <property type="gene ID" value="Caci_6271"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6271"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_416606_0_0_11"/>
    <dbReference type="OMA" id="RIVIYED"/>
    <dbReference type="OrthoDB" id="1043172at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="658" mass="72262" checksum="14D2D63247463942" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK52</accession>
    <name>C7QK52_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6272"/>
    <dbReference type="EnsemblBacteria" id="ACU75126">
        <property type="protein sequence ID" value="ACU75126"/>
        <property type="gene ID" value="Caci_6272"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6272"/>
    <dbReference type="eggNOG" id="ENOG50336VX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911176_0_0_11"/>
    <dbReference type="OMA" id="PACHAPD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981749" evidence="1">
        <location>
            <begin position="26"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="31756" checksum="9CB02AFACC21C6E5" modified="2009-10-13" version="1" precursor="true">MRSVVAAAVLSGLLALAGCSSGAHAAHQRAARAATPDSIGASRPSWILTKVALNALASNPNVRARLSGAQIFEILSGAERPATALPVVPTMSFKSFATLQDTLSRGSLPPDIRAVIYDAEHWSQTPSKEQRDPASFYQRAADLVHAHGLIFIATPAMDLVNADGGKAADPAAAFVDRHIGSDAARDADVVDIQAQSLERDAAKYGGFVEQVTSQIRAVNPKAVVVAGLSTNPPGTGITPEMLVAAMLATGDRTTGFWMNVPGKGDDCPTCNQPRPDIAVAALEDGRLARLPRVFGSVNALPNPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK62</accession>
    <name>C7QK62_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794865.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6282"/>
    <dbReference type="EnsemblBacteria" id="ACU75136">
        <property type="protein sequence ID" value="ACU75136"/>
        <property type="gene ID" value="Caci_6282"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6282"/>
    <dbReference type="eggNOG" id="COG2130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820597_0_0_11"/>
    <dbReference type="OrthoDB" id="474248at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N_2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="35700" checksum="915D521A1B281BB6" modified="2009-10-13" version="1">MIVPEHGLAVQLVSRPEGPLAREHLAVVETPVPRLAPGWVLVRNLFVTLDPHPAASPARRWPLYTAVGAGSLVGEVVASRSADVPHGSLIAHRGGWSTYSALPRGGYATRVLEPAAGVPIDAYLTVLGLPGLAAHVALTRVLQVGRGESLFIAGAADPVGSATARIARMLGASRIVGGVSSPGGARRAAQDPYFDAVFERGTDRFGASEAFDAYAGVDAAFVGTAQPDLSDALTWVRDLGRVAWLHDTPQGSVEATVSVDLSMVHRRGIRIEGFGLQHHLHRFKEIEAQYADELRTGVLDPGRIADVDFHGLIDVLVAAARSDFQPADAYRLTGESAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKJ7</accession>
    <name>C7QKJ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ordered locus">Caci_8273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796821.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8273"/>
    <dbReference type="EnsemblBacteria" id="ACU77096">
        <property type="protein sequence ID" value="ACU77096"/>
        <property type="gene ID" value="Caci_8273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8273"/>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027486_1_0_11"/>
    <dbReference type="OMA" id="HNKYVVD"/>
    <dbReference type="OrthoDB" id="1311145at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="35384" checksum="7549EE17BD07D8EA" modified="2009-10-13" version="1">MGTMNASAPEDRRVLLAAPRGYCAGVDRAVVTVEKALELYGAPVYVRKEIVHNKHVVQTLQNRGAVFVEETDEVPEGATVVFSAHGVAPIVHEEASRRRLKTIDATCPLVTKVHKEAVRFAEQDYDILLIGHDGHEEVVGTTGEAPEHIVLVDGPDSVADVQVRDPAKVAWLSQTTLSVDETTATVDRLREKFPLLLDPPSDDICYATQNRQIAVKRIAADSDLVIVVGSKNSSNSVRLVEVALEAGAGAAYLVDFASEISEDWLEGVRTVGLTSGASVPEDLVDGVLSWLAERGYGTVEVVRSAEEKLLFALPPELRKDMREGSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ3</accession>
    <name>C7PVZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786678.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2467"/>
    <dbReference type="EnsemblBacteria" id="ACU71385">
        <property type="protein sequence ID" value="ACU71385"/>
        <property type="gene ID" value="Caci_2467"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2467"/>
    <dbReference type="eggNOG" id="COG2706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038716_3_0_11"/>
    <dbReference type="OMA" id="NGPHAHM"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="351" mass="36465" checksum="CA783F43EB866775" modified="2009-10-13" version="1">MVDSTNSYLLVGGYGAGVHCLRYDADGALSPVSSVDIADPSYVAYDGARGVLTAVVEQEPAGRVASARFTVAEGGSDVRDQTASGGAAPCHLALHPDGSTLFVANYVSGTVGVFPIDAEGRVTGSEPAQLIQHTGSGPRADRQEGPHAHQVTVSPSGRWVLAVDLGTDTVYVYAYEAGRLTEHGVVTLPGGSGPRHLAFHGSGRYFYLLNEVSWTVAVCSWDEATGAGEVGQLVQSRAEADRAKSDHAWCAAIRVSADDRFLYASNRVDDTIAVFAVAADGATLEPVEVVPAGGAWPRDIVLSPDGTLLFSANQHSDSITVFRVDAASGRLTPVGTPYAVTTPASLLPISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ8</accession>
    <name>C7PVZ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein alpha/beta-subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786683.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2472"/>
    <dbReference type="EnsemblBacteria" id="ACU71390">
        <property type="protein sequence ID" value="ACU71390"/>
        <property type="gene ID" value="Caci_2472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2472"/>
    <dbReference type="eggNOG" id="COG2086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060196_2_0_11"/>
    <dbReference type="OMA" id="GIDSKMN"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="22"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27148" checksum="0ED1C7F1D452A1CA" modified="2009-10-13" version="1">MKIVVLTKHVPQAIAEVSFAQDLTVDRSAVRCRLQDADEYAVEQAARIACRRLDVQVTAVTMGPSGASAALRAALARGADEGVHVLDDALHGSDAPATSLVLAAVCRRLGFDLVLCGSASTDSAMSVIPAMLAERLGVPALCCCDSLRTEEDMLHATRDDGAATEELAAAMPAVVSVTDRSGEPRYPRFEAISDARQKLVRTWSLADLGIETADVGLAATATKVGRVIRTEAGSTAVAEDPASAATRIADFLTRRQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW75</accession>
    <name>C7PW75_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vault protein inter-alpha-trypsin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793052.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4460"/>
    <dbReference type="EnsemblBacteria" id="ACU73323">
        <property type="protein sequence ID" value="ACU73323"/>
        <property type="gene ID" value="Caci_4460"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4460"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011139_0_0_11"/>
    <dbReference type="OrthoDB" id="271104at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="20"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="318"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1033" mass="106031" checksum="D63570D508D8E28D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK7</accession>
    <name>C7PWK7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795016.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6435"/>
    <dbReference type="EnsemblBacteria" id="ACU75287">
        <property type="protein sequence ID" value="ACU75287"/>
        <property type="gene ID" value="Caci_6435"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6435"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_22_1_11"/>
    <dbReference type="OMA" id="SEWMKLD"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="19190" checksum="B4FA9C883EDCF6C2" modified="2009-10-13" version="1">MSPRTADHDNAEPSTAAHPARAVAGTVDRVTDALLTASRLLVAVSARSLNEVEDSLTLPQFRALVVLSSRGPLRLTHLAEHLAVNPSTAMRMAERLAAAGMIDRSPNPENRRESIATLTAAGREVVEQVTSRRREEITTIVERMPPDHLDRLVEALESFSAAGGEPSAGYDPIPLGWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWZ0</accession>
    <name>C7PWZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_8424</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796972.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8424"/>
    <dbReference type="EnsemblBacteria" id="ACU77247">
        <property type="protein sequence ID" value="ACU77247"/>
        <property type="gene ID" value="Caci_8424"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8424"/>
    <dbReference type="eggNOG" id="COG2898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_7_3_11"/>
    <dbReference type="OMA" id="RWEPRFV"/>
    <dbReference type="OrthoDB" id="542304at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031553">
        <property type="entry name" value="tRNA-synt_2_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16995">
        <property type="entry name" value="tRNA-synt_2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_2_TM" evidence="10">
        <location>
            <begin position="26"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="LPG_synthase_C" evidence="9">
        <location>
            <begin position="263"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="587"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU77247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="701" mass="77160" checksum="29ABE526CA3F672A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN0</accession>
    <name>C7PXN0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Big_3_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2565"/>
    <dbReference type="EnsemblBacteria" id="ACU71483">
        <property type="protein sequence ID" value="ACU71483"/>
        <property type="gene ID" value="Caci_2565"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2565"/>
    <dbReference type="eggNOG" id="ENOG5033ZWT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123762_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032109">
        <property type="entry name" value="Big_3_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16640">
        <property type="entry name" value="Big_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981335" description="Big_3_5 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Big_3_5" evidence="2">
        <location>
            <begin position="41"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="19046" checksum="6E63111033CE9106" modified="2009-10-13" version="1" precursor="true">MQSWHKRSAWTTVAFAALAVVVFASPASAQAVSSTTVTASPSTAATGQSVELDAAVTCAGDPSGGLGMTFFDGGDLLTTVPVAADGTASFTTSFTTTGAHTITAAYNGNDNCDASNNTTTVQVTTAPTPPPNPTPNPPGLCLLTCGSLINLNFADTYNIHKTYNVYNTYNFYQPGNGASPAPAAGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXQ5</accession>
    <name>C7PXQ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2590"/>
    <dbReference type="EnsemblBacteria" id="ACU71508">
        <property type="protein sequence ID" value="ACU71508"/>
        <property type="gene ID" value="Caci_2590"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2590"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057319_0_0_11"/>
    <dbReference type="OMA" id="VSACGMP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="41891" checksum="F0D617E7C65FD4D1" modified="2009-10-13" version="1">MLNGQARTAVAELAAAVLSLRPMIDRLDAPVRVAVPGGARGAVRGLQTIVDRVCGRLGAPALELVRSPESDLDPFGAAAGRRLGLADSGAALAVLSSDDLPDVDRVVDEAVSADFDSFCEQRTVRGPDGVGVRAYAAGDPDAPAVVIASACGMPARLAEVWIRRLARDHRVLTWESRGLFCGCEDFAGATGVPAQADDLIAVMDAFELDQAHVMGLCGGAVIAITAAAAHPDRISSLSLWHGDFELGDQARKTEHQRNLQALMTMATRAKVSAAGVHAVLCRSIAASTPPELAHLVLYPYASPDLLFRYCLLNGAIMETDVRPELSAVVQPTLVVTSEDDTTAHPDGSRYVAAALPDARLHVVPHGDHISLFQGPPDLIDTASRFMAEKSDVNPSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN4</accession>
    <name>C7PYN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Collagen triple helix repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8533"/>
    <dbReference type="EnsemblBacteria" id="ACU77356">
        <property type="protein sequence ID" value="ACU77356"/>
        <property type="gene ID" value="Caci_8533"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8533"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_606482_0_0_11"/>
    <dbReference type="OMA" id="PVTKPPC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="451" mass="42693" checksum="ACF1B4BB81C1BDAF" modified="2009-10-13" version="1">MSQDSQKSVGALQKCVMVTTGLTVLAGATLTVVGVRPGTAHDHHTRTEAAARTVPLSVAAFSAPPAAKVTRIADTTTLSAAVHPPLHQAAVQHTMPHAVHHAAAQHAVPHAFAPKADGMPLPPRPPAHVFVPRHHATHPHAHHPMAHKVCHHKPHEKCECVGKPGPTGPRGPVGPMGMKGDTGATGPTGPGGGATGPTGPTGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGPTGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGATGTTGATGPAAPDIDLVFHSESAAEQVTLFNNVLNYRLVNGSGTRGAAQPLSTLANYPGTAADNVVDVSEAIQHDTLFVDVVTAGGHAAELVCTLSGSRGLDNGATPAVACNSGTTAAPVYWVTIPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYR0</accession>
    <name>C7PYR0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">bPH_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8563</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8563"/>
    <dbReference type="EnsemblBacteria" id="ACU77382">
        <property type="protein sequence ID" value="ACU77382"/>
        <property type="gene ID" value="Caci_8563"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8563"/>
    <dbReference type="eggNOG" id="COG3428">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1101341_0_0_11"/>
    <dbReference type="OMA" id="IRVRRHW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="89"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27860" checksum="DA15A460790115A0" modified="2009-10-13" version="1">MLLRPELEDRAKRYLVPGERLVIAVRHHLAAVIIPVLIAVAAVVLAMGIDIFSSPDAGQFRLGAWAVAGVAFLYMAWNVAVWNQDLLIVTNKRILHTHGVITRSFDALPLGKVNDMRVERDLLGRILGYGRFNAKAVGDAPLGRRGLDFISHVEETWLEISNLLYGPGAKSGPKDPQEVRIVGAVLPDMHGEPVEIVMPPVSVKSPADDDKAHPVNAAMLPVKVFRDDKGERAFETDVTTPGNKRRRIRFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYV9</accession>
    <name>C7PYV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784810.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0578"/>
    <dbReference type="EnsemblBacteria" id="ACU69515">
        <property type="protein sequence ID" value="ACU69515"/>
        <property type="gene ID" value="Caci_0578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0578"/>
    <dbReference type="eggNOG" id="COG2346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103526_2_1_11"/>
    <dbReference type="OMA" id="HQKAFLT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="13620" checksum="559002F238069BCD" modified="2009-10-13" version="1">MSESQNQSQWERVGGEAAIKAVLDRFYEGVLDEPQLAGFFESVAVDDIKPHMAEVLQVVLGGPGARTDIDLAGYLTEAHADLGVSLSDFELTGKVLLDTLEEFSVPDDIVETIEGVLATVQPFVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYW7</accession>
    <name>C7PYW7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="9">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">metG</name>
        <name evidence="13" type="ordered locus">Caci_0586</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784818.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0586"/>
    <dbReference type="EnsemblBacteria" id="ACU69523">
        <property type="protein sequence ID" value="ACU69523"/>
        <property type="gene ID" value="Caci_0586"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0586"/>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_1_2_11"/>
    <dbReference type="OMA" id="YMRMAGH"/>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="11">
        <location>
            <begin position="9"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="12">
        <location>
            <begin position="429"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="355"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="605" mass="67198" checksum="2785E68000065A04" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX0</accession>
    <name>C7PYX0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ordered locus">Caci_0589</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784821.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0589"/>
    <dbReference type="EnsemblBacteria" id="ACU69526">
        <property type="protein sequence ID" value="ACU69526"/>
        <property type="gene ID" value="Caci_0589"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0589"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_1_1_11"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="52"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="32468" checksum="CE206A2EE28E0586" modified="2009-10-13" version="1">MSETPHSPPPTPEPDRLPARLLGPAEVRRLAEKLGVSPTKKLGQNFVIDPNTIRRIVRAGDVTAEDVVVEVGPGLGSLTLGLLDVARRVVAVEIDPVLAAALPDTLAEFAPGIAAGQAEFELVRADALRIAELPGSPPTALVANLPYNVAVPVLLHMLERFPSIERTLIMVQSEVADRLAAEPGGRVYGVPSVKARWYADVKRAGAIGRSVFWPAPNVDSGLVRLDRRAVPPSTKAGRRDVFAAVDAAFAQRRKTLRSALSGWAGSPAAAETALTAAGINPSARGETLTVEEFARLAEHRPQREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZR0</accession>
    <name>C7PZR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4714"/>
    <dbReference type="EnsemblBacteria" id="ACU73575">
        <property type="protein sequence ID" value="ACU73575"/>
        <property type="gene ID" value="Caci_4714"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4714"/>
    <dbReference type="eggNOG" id="COG0235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_3_0_11"/>
    <dbReference type="OMA" id="YATFGTH"/>
    <dbReference type="OrthoDB" id="599627at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="10"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24500" checksum="6714BE8A853B7B39" modified="2009-10-13" version="1">MSTDIARIRREVCDLHAELVRYQLVVWTAGNVSARVPGEDLLVIKPSGVSYDDLTPANMIVCDLDGKVVQGDLSPSSDTAAHAYVYRNMPEVGGVVHTHSTYASAWAARGEAVPCVLTAMADEFGGEIPVGPFALIGDDSIGRGIVETLAGSRSPAVLMRNHGVFTVGGSAKAAVKAAVMTEDVARTVHLARAHGRPQPIGEQDIASLYDRYQNVYGQSSDRSAAEGDAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZY6</accession>
    <name>C7PZY6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Topoisom_I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6633</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795208.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6633"/>
    <dbReference type="EnsemblBacteria" id="ACU75479">
        <property type="protein sequence ID" value="ACU75479"/>
        <property type="gene ID" value="Caci_6633"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6633"/>
    <dbReference type="eggNOG" id="COG3569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046978_1_1_11"/>
    <dbReference type="OMA" id="QYRYHPR"/>
    <dbReference type="OrthoDB" id="812517at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.66.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035447">
        <property type="entry name" value="DNA_topo_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55869">
        <property type="entry name" value="SSF55869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topoisom_I" evidence="5">
        <location>
            <begin position="81"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="37698" checksum="E27B3D220C0FA3F3" modified="2009-10-13" version="1">MTRLRHSRTLDPGLRRIRHGSGFRYVDAAGEPVDADTKQRIKELVIPPAWEDVWICPWPNGHIQATGVDDAGRRQYLYHPQWRERRDRLKHDHALEFARRLPKIRAIVDDGLAGDGLGRERVLCAAVALLDVGVFRIGNNQYAQANGSYGLSTLRRKHVRIHKGEAEFSYLAKGGLKRAEHISDPRVVAVLRGLLRRKGGGYQLLAFHEDSRWQPIRSQHVNDFLREISGMEITAKDFRTWHATVFAAVALSVSTHADSSQTARRRAVTRAVAETAAYLGNTPAVCRASYIDSRLIDRFLHGETIATALPDLGRDTPPGVPAIQGDAEHAVLRLLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q009</accession>
    <name>C7Q009_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75502">
        <property type="protein sequence ID" value="ACU75502"/>
        <property type="gene ID" value="Caci_6656"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6656"/>
    <dbReference type="HOGENOM" id="CLU_1746341_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="16714" checksum="48BE4AE5F9350BB4" modified="2009-10-13" version="1">MQGISVPIIILGIYIVWKGLVEGLFPALRTVTIRRHGLPAVGTVVANRSRRIDSLQRINAGIYVPRVSYRQQGLVSFTTAEGQRVTFWANLDGWDTPKPEKGTYQLRYLPEDPHAHRFTRPRLVSYWVTAVVGLISGGAFVGLAWFLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0J6</accession>
    <name>C7Q0J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797253.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8714"/>
    <dbReference type="EnsemblBacteria" id="ACU77529">
        <property type="protein sequence ID" value="ACU77529"/>
        <property type="gene ID" value="Caci_8714"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8714"/>
    <dbReference type="eggNOG" id="ENOG50338DX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_194662_0_0_11"/>
    <dbReference type="OMA" id="CAVEFML"/>
    <dbReference type="OrthoDB" id="2059397at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9635" checksum="36A2D43D0DF7960C" modified="2009-10-13" version="1" precursor="true">MSNGVVLASGSGGTSGGLIAVVIIAIIFTAIAVSIVSFFQLQKHRADAVAFASYRKLAEEAVEKQDQLLTELRSLDLKVGEIERMLRSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q165</accession>
    <name>C7Q165_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787033.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2831"/>
    <dbReference type="EnsemblBacteria" id="ACU71740">
        <property type="protein sequence ID" value="ACU71740"/>
        <property type="gene ID" value="Caci_2831"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2831"/>
    <dbReference type="eggNOG" id="COG1502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104151_0_0_11"/>
    <dbReference type="OMA" id="SALMHPR"/>
    <dbReference type="OrthoDB" id="1992731at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19425" checksum="3B211737A29367D5" modified="2009-10-13" version="1">MPLSDLTALDKHKTDGFPAGYPVNFRTFYSPVDDVHGALAELIASAQRSLVVAMFGFDDDELAAALHEKLDSEHCYVQLTLDKSQSGGAHERALLAKEAYPSNSIAIGHSEKGAIMHLKMVIVDGLDVLTGSTNWSTSGESMQDNAAIVIRDPHVAAEARSRLDLIHQHMLMTAAKSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q172</accession>
    <name>C7Q172_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787040.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2838"/>
    <dbReference type="EnsemblBacteria" id="ACU71747">
        <property type="protein sequence ID" value="ACU71747"/>
        <property type="gene ID" value="Caci_2838"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2838"/>
    <dbReference type="HOGENOM" id="CLU_1657670_0_0_11"/>
    <dbReference type="OMA" id="DIINAWM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="16742" checksum="CD602E7EED0C9B4A" modified="2009-10-13" version="1">MGFESPRTVLVLDFTDTDLAGLEVRMRSQTVQELKDGTARMASIASVAKSVLGLDPNDEAAAQAAIAGLDTEALDAVDDTFADFAKHLVSWNLTENGVDVPATLEGIGAQDSRFILRLVGAWQQGMSGVDNPLPRSSSNGRPPDALSMPMVPLEASLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1B3</accession>
    <name>C7Q1B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4781"/>
    <dbReference type="EnsemblBacteria" id="ACU73642">
        <property type="protein sequence ID" value="ACU73642"/>
        <property type="gene ID" value="Caci_4781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4781"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079365_0_0_11"/>
    <dbReference type="OMA" id="FEWKLYG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="130"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="28864" checksum="C0346DA6A1F87126" modified="2009-10-13" version="1">MTSPTTDKALLALFDHRMRATADPDEPAARVEHIDGIVRQIGAHPTDWHGIVYADIDATTADAAIQAQIAHFRTLGADFEWKHYSHDEPADLPARLQAAGFEADEPETLFVAEITQLSGAGLTETLPEGITLRPVTTEADADLVAEAANAAFGSGGDRARARVLARLAADPETVWTWLAMAGDRPVSAARMLIHPGTAFASLWGGGTAPEWRGRGIYRALVARRMQVAAELGCEYLQVDATDMSRPILERLGFRALSVTTPYEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C8</accession>
    <name>C7Q1C8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4796"/>
    <dbReference type="EnsemblBacteria" id="ACU73657">
        <property type="protein sequence ID" value="ACU73657"/>
        <property type="gene ID" value="Caci_4796"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4796"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_3_0_11"/>
    <dbReference type="OMA" id="NIGESYH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982782" evidence="1">
        <location>
            <begin position="41"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="48"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="29122" checksum="98CED7DB6FFECC81" modified="2009-10-13" version="1" precursor="true">MLPRPHKRTRTRRPAIKRALLVLAAVTTAFTTVMATDASAASSVHYVALGDSYSSGVGSGSYISSSGNCLRSTLAYSQLWANAHSPASYTSVACSGATTTDVLNSQISALSSSTNLVSITIGGNDVGFSSVMQTCVLDSDSTCLSAINASVAQAKSVLPGKLGTTFSAIRSAAPSARVVVMGYPEFYDLGNSWICPGLSTTDRTALNNAADTLDGIIQTAAKNAGDSYADVRSKFSGHELCDFFNEWLHSVNITDVTESYHPTADGQSGGYLPAMDSITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D5</accession>
    <name>C7Q1D5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4803"/>
    <dbReference type="EnsemblBacteria" id="ACU73664">
        <property type="protein sequence ID" value="ACU73664"/>
        <property type="gene ID" value="Caci_4803"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4803"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010756_0_0_11"/>
    <dbReference type="OMA" id="ARTEWNP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="54"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="597"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="976" mass="103052" checksum="DE9CC936C484E8E4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1L6</accession>
    <name>C7Q1L6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793474.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4885"/>
    <dbReference type="EnsemblBacteria" id="ACU73745">
        <property type="protein sequence ID" value="ACU73745"/>
        <property type="gene ID" value="Caci_4885"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4885"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="QICMTTG"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="19"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="50693" checksum="B1D6DC61C3B859B5" modified="2009-10-13" version="1">MPLLEGVDWHGNIFLSGKWVRGGGGDYAVVEPATGAELGRMGRAGVEDVARAAHAAAQAQREWAALPHPARAAVLRRAGDLWQEHAEEISWWNVREVGAVPGMAAFSLHVAAEECYEAASLPSRPLGEVLASEQPRLSMARRVPAGVVGVISPFNVPIILGIRSVAPALALGNAVLLKPDPRTAVTGGALMVRIFEEAGLPADVLQLLPGGADVGEALITDPRVRVVSFTGSTAVGRRVGELAGRHLKRAHLELGGNSALLVLEDADVQEAVNLAAWGSFFHQGQICMTTGRHLVAESVHDAFVEALAAKAAALPVGDPATGQVALGPVIDAGQRDRIHGMVTATVEAGAALAAGGTYEDLFYRPTVLADVPIGAPAFAEEVFGPVAPVTRVGSVEEAIAVANAGEYGLSLGIVTRDVMRGLEIAEKIPTGIVHINDQTVNDEANAPFGGVRGSGTGARFGGAQANIEAFTETRWITMRGQAPAYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1S6</accession>
    <name>C7Q1S6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chlorite dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6785"/>
    <dbReference type="EnsemblBacteria" id="ACU75627">
        <property type="protein sequence ID" value="ACU75627"/>
        <property type="gene ID" value="Caci_6785"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6785"/>
    <dbReference type="eggNOG" id="COG3253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076582_1_0_11"/>
    <dbReference type="OMA" id="RYTMWSV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010644">
        <property type="entry name" value="ChdC/CLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36843">
        <property type="entry name" value="PTHR36843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06778">
        <property type="entry name" value="Chlor_dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="29014" checksum="608A97FB48E4D0CD" modified="2009-10-13" version="1">MSDSGNETQDERPAGVVSNVRIGKRAVELNEVTRYAMWTVFKVREDLPASDDARADLAAEVETLLETLAKDDVVLRGSYDVSGFRHDADFMLWLHAETSEALQDAYQRFRRTAFGRLTEPVWSQMALHRPAEFNKSHVPAFVADETPRGYIAVYPFVRGYEWYLLEDAERRRLLAEHGMMSREYPDVRANTVPAFALGDYEWILAFEADALDRIVDLMRHLRGSETRRHVREEVPFYTGKRRSITEIVTALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2A1</accession>
    <name>C7Q2A1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8825"/>
    <dbReference type="EnsemblBacteria" id="ACU77638">
        <property type="protein sequence ID" value="ACU77638"/>
        <property type="gene ID" value="Caci_8825"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8825"/>
    <dbReference type="HOGENOM" id="CLU_1018171_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981383" evidence="3">
        <location>
            <begin position="36"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="26510" checksum="FE64C89366A7EF37" modified="2009-10-13" version="1" precursor="true">MGRQPEHMKRVTGRVAAVGGAAALAAAALTVFAPAAGAGTASVGYGSCTSSNPALAAPPPNYTSQVTLTPQGSSFQAGKAITITWHYSISTAPGPVGIPVAKVATAKAKIVIAGAASSTVTTGSSANFPPEPVTPGKTFQIPDMTATFTPSAAGTYTLTPGDNEQDVAQFGVVVKCKASASGPAATITVGPASGGGGATSTTSSPSTGTSSTGTPSTSAPSTSVDSSPSTSSTDGVLPHTGFDGRWLAGGVVLAAALGAGSLYATRRRRGTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2H4</accession>
    <name>C7Q2H4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0883</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785111.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0883"/>
    <dbReference type="EnsemblBacteria" id="ACU69816">
        <property type="protein sequence ID" value="ACU69816"/>
        <property type="gene ID" value="Caci_0883"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0883"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288330_0_0_11"/>
    <dbReference type="OMA" id="FETNTRP"/>
    <dbReference type="OrthoDB" id="509439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981385" evidence="6">
        <location>
            <begin position="30"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="8">
        <location>
            <begin position="54"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="212"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1146" mass="117065" checksum="D441AC8A4C51CB4C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q341</accession>
    <name>C7Q341_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793506.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4917"/>
    <dbReference type="EnsemblBacteria" id="ACU73777">
        <property type="protein sequence ID" value="ACU73777"/>
        <property type="gene ID" value="Caci_4917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4917"/>
    <dbReference type="eggNOG" id="COG3875">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050189_0_0_11"/>
    <dbReference type="OMA" id="GSVEPHY"/>
    <dbReference type="OrthoDB" id="313921at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="426" mass="45290" checksum="3EF092C96EA0DC68" modified="2009-10-13" version="1">MRIRLAYGESGLDIEVDPAVTTVVEPVHHEVAADQAAVLRAALRDPVAGPPLRERVRPGQTVAISACDGTRPQPRHLMIPAILAELDGVVRLDDIVILVATGTHRGNSDAELRRMFGGEVVDSVRIVNHDARDRRRLAWMGTFGAGVPVWLNREWTEADVRITTGFVEPHFFAGFSGGPKLVAPGLAALETVLVLHDASRIGDPRATWGVIHGNPVHDDVRAIAEATGVTFAFDVVLNRGQEVVAAFGGDLLPMHAAATALARRIAMREVGAPFDVVVTTNSGFPLDQNLYQAVKGMSAAYQVLKPGGVIVCAAECRDGFPDHGSYREVLASAASPRALLEAISARTETVPDQWQVQIQARIQAASRVVMHTSHLSDADLAAAHLEQTADISATVAEALAAAGPAARLCVLPEGPQTIPYLAGRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3A1</accession>
    <name>C7Q3A1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793566.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73837">
        <property type="protein sequence ID" value="ACU73837"/>
        <property type="gene ID" value="Caci_4977"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4977"/>
    <dbReference type="HOGENOM" id="CLU_992850_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="29778" checksum="EC17185FF8897DA4" modified="2009-10-13" version="1">MTTPALAKDDEPLIPRPLSILAAISIAVHVVLLGMACLGAKAAGHAGLPADHAWGWYLVVGAAWSIGIGSFGLSWGARATTRFGGTGSSARVGWCLAGMWLGYVWPVPITAAAVAFAVWPRRPSRADQIWPKPVDTNKRRRQIAARIAAAALAALVAIAGSTWGLRAHAAKFHQLSDAPGSSVLGTWRAGGMTITLRPHGIYTASDLTAATMQDTTDFPPSTGTWQLARSGPDHLNSVQLRPSQDRFLELPVYQVSSKDYLCAEADPDSPCDIVFHRDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E1</accession>
    <name>C7Q3E1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6867"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH76">
        <property type="family name" value="Glycoside Hydrolase Family 76"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75706">
        <property type="protein sequence ID" value="ACU75706"/>
        <property type="gene ID" value="Caci_6867"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6867"/>
    <dbReference type="eggNOG" id="COG4833">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044209_0_0_11"/>
    <dbReference type="OMA" id="YDDKAWL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980571" evidence="1">
        <location>
            <begin position="35"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="365"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="49855" checksum="99B5FDD590230378" modified="2009-10-13" version="1" precursor="true">MKARTGKTRILGAVVTAAALAVSVLIGAAGTASAASPAAIGAAALMKSYDSTTGQIGTGWWNSAVALSTIETYQQTTGDSSYAYAMSGAFAKHQSSNFENEYMDDTGWWALAWVQAYDITGNSAYLQMARTDADYIHGYWDSTCGGGVWWSKAKGYKNAIPNELFLELTADLHNRIPGDTQYLGWAKQEWSWFSGSGMINSSHLVNDGLSSSCKNNNGIAWSYNQGVVLGGLAALSQATGDTSLLTTARQIADAATSSLSQNGVFTESCEPTNCNQDQVSFKGIFVRGLRTLASAAGTSAYDAWFTAQAGSIEAHDTSATGFGVSWAGPIRQLSSSSTASAEDALVAALPGAGTPAGAMKSGIAGKCLDDPKGSSTPGTKAQLWDCNGGSTQQWTVVGQTLRVQGLCLDITGARTANGTLVELWSCNGGANQNWTSANGAVANPATGKCLDVPHSSTTNGTQLQIWDCNGGANQKWILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E9</accession>
    <name>C7Q3E9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 76</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795442.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6876"/>
    <dbReference type="CAZy" id="GH76">
        <property type="family name" value="Glycoside Hydrolase Family 76"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75714">
        <property type="protein sequence ID" value="ACU75714"/>
        <property type="gene ID" value="Caci_6876"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6876"/>
    <dbReference type="eggNOG" id="COG4833">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_539738_0_0_11"/>
    <dbReference type="OrthoDB" id="504223at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982858" evidence="1">
        <location>
            <begin position="25"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="411"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="514" mass="55935" checksum="580A6934D64E051E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3F3</accession>
    <name>C7Q3F3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6880"/>
    <dbReference type="EnsemblBacteria" id="ACU75718">
        <property type="protein sequence ID" value="ACU75718"/>
        <property type="gene ID" value="Caci_6880"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6880"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069129_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="54"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="27472" checksum="21F5663F513A8220" modified="2009-10-13" version="1">MTDSCKVEALEEASLLYREPALYAEMADAEAVDTAAAIVALADRHGPAGADSLLDVGCGTGAVLEQLACKYSKSAGVDLLPGMIEISRERRPQLETYVGDMRTIRLGRSFEVVTCIGNALAYLTAPDDIEAAFATFAGHCVPGGVLVIRTLTAFPPLDRSRTSRTRVSGRSANVTTTYTRDPAAEVLILTRHWDFEDREPATDVIRRRVLTIGEQESFAAAAGFTLVRPRDEDEDMTIFIRDDAGDLRSGVADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S6</accession>
    <name>C7Q3S6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797408.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8871"/>
    <dbReference type="EnsemblBacteria" id="ACU77684">
        <property type="protein sequence ID" value="ACU77684"/>
        <property type="gene ID" value="Caci_8871"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8871"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="CGHCIDM"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="26"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="161" mass="17447" checksum="9E768235FD863C0F" modified="2009-10-13" version="1">METRFDLSASPTASKLLKRFYSTSQVIEKSSLPKTLQDLVSLRVSQINGCGWCVDIHTKEAAAAGETPLRLNLVATWRHSTVFTESERAALALAEEGTRITAPGEVVSDATWAAARTQFDDDQLGTLICLIAMMNATNRISLIPNLLGGSYEPGMFAALEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U9</accession>
    <name>C7Q3U9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8894</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8894"/>
    <dbReference type="EnsemblBacteria" id="ACU77707">
        <property type="protein sequence ID" value="ACU77707"/>
        <property type="gene ID" value="Caci_8894"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8894"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="DNMVLTV"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="14"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="519" mass="53176" checksum="BD3AF1E24572D120" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q415</accession>
    <name>C7Q415_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8960"/>
    <dbReference type="EnsemblBacteria" id="ACU77773">
        <property type="protein sequence ID" value="ACU77773"/>
        <property type="gene ID" value="Caci_8960"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8960"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054109_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041496">
        <property type="entry name" value="YitH_GNAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18014">
        <property type="entry name" value="Acetyltransf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="31606" checksum="98AA47FA12C61CF7" modified="2009-10-13" version="1">MTALQTPHADAPTAEPWAGRFVATRGTAADAALIEGWAGGAGWSLGRGDLDLFTRHRPGGLLIGVLDGRPVSAMATAGYDNGFCFTGALIVDPGFRGRGIGTATADIVLSHAEGRPVGLEAPPTLRDFFAARGFFARRRTIAFAGAVPAPRAINPHVTTLDSGLLGQAAALDARCFPAERTALAADWAIGPDRYALGFVQNNRLLGYGVIRAGFGAARIGPLYASEPRVAAALFDALAEHAGRHGARAIAIDIPEPNPAAMALCETRGLSHDSETLRMVRPGACGDETAVDVTLLYGLTSRELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4K9</accession>
    <name>C7Q4K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787271.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3069"/>
    <dbReference type="EnsemblBacteria" id="ACU71978">
        <property type="protein sequence ID" value="ACU71978"/>
        <property type="gene ID" value="Caci_3069"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3069"/>
    <dbReference type="eggNOG" id="ENOG5033YQ7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075566_1_0_11"/>
    <dbReference type="OMA" id="RVRESIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="237" mass="24582" checksum="B100837892F27453" modified="2009-10-13" version="1">MPTAEPSPPTLRAARAAVFAALCVLVGAVGHDAFSVGAIPLWALLVGGGAVFLVVAPLTQRERGLPTILALMAVVQLGLHELFASAQGSAASMSMPMAMPMPMATPMPPRGEFWCGHSEPAGVTQAMQNVAMPTTAAPHHSMTSGMTTGMIAAHVLAALVAAWWLRRGEAAVWSLARTLGLALITPLVLLVVALVPWTPPRRVGAVATRTPARLGPGRLLRFDVARRGPPMTAAAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4P5</accession>
    <name>C7Q4P5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ordered locus">Caci_3105</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3105"/>
    <dbReference type="EnsemblBacteria" id="ACU72014">
        <property type="protein sequence ID" value="ACU72014"/>
        <property type="gene ID" value="Caci_3105"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3105"/>
    <dbReference type="eggNOG" id="COG0036">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_2_1_11"/>
    <dbReference type="OMA" id="WLQVDGG"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="148"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="181"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="203"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU72014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24514" checksum="FE9A6DF6A181FCE7" modified="2009-10-13" version="1">MICQTLPMSSVQISPSILSADFARLADEVGAVPSADWIHVDVMDNHFVPNLTLGLPVVEALVKASPRPLDCHLMIADPDRWAPGYAEVGAGSVTFHVEAARAPIRLARSLRSAGARAGMALKPATPIEPYEDLLGELDMVLLMTVEPGFGGQKFLDVVLPKIRRTRQMINRHGGSVWLQIDGGVAADTIERCAEAGADVFVAGSAVYGAEDPDRAIQALRAQAEAAGARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4X7</accession>
    <name>C7Q4X7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793654.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5065"/>
    <dbReference type="EnsemblBacteria" id="ACU73925">
        <property type="protein sequence ID" value="ACU73925"/>
        <property type="gene ID" value="Caci_5065"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5065"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_0_8_11"/>
    <dbReference type="OMA" id="HTVMEPE"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2236"/>
            <end position="2311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="561"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="568"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="2333" mass="249844" checksum="E70535F65C55A9DD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q535</accession>
    <name>C7Q535_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glpK</name>
        <name evidence="9" type="ordered locus">Caci_5124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793712.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5124"/>
    <dbReference type="EnsemblBacteria" id="ACU73983">
        <property type="protein sequence ID" value="ACU73983"/>
        <property type="gene ID" value="Caci_5124"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5124"/>
    <dbReference type="eggNOG" id="COG0554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_11"/>
    <dbReference type="OMA" id="PESGWHE"/>
    <dbReference type="OrthoDB" id="233605at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="265"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="249"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="416"/>
            <end position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="506" mass="55289" checksum="03D42A75899D79BE" modified="2009-10-13" version="1">MADYVGAVDQGTTSTRFMIFDHGGNEVARHQLEHEQILPKAGWVEHNPTEIWERTRAVIETAMNKAHLHAADLAALGITNQRETTMVWNRHTGRPYYNAIVWQDTRTDRIAAALDADERGQVIRRKAGLPPATYFAGGKIQWLLENVEGLRADAEAGDAIFGTMDSWLIWNLTGGVDGGVHVTDVTNASRTMLMDLETLDWDEELLGFFNVPRAMLPAIRPSSDPAGYGKTRADGPLRGEVPLTGDLGDQQAATVGQVCFTPGTAKNTYGTGNFLLLNTGKEIVRSENGLLTTVAYKFGDEDAVYALEGSIAVTGSAVQWLRDQLGIISGAAQSEALARQVEDNGGVYFVPAFSGLFAPYWRSDARGAIVGLSRYNTNAHLARATLESIAYQTRDVVEAMEQDSGVRLDVLRVDGGVTANELAMEIQADVLGVPVSKPVVAETTALGAAYAAGLAVGFWRTTEELVSNWNEDKRWEPRADEAARAKGYRNWKKAVDRTLNWVEFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5G0</accession>
    <name>C7Q5G0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Silent information regulator protein Sir2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7099</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795657.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7099"/>
    <dbReference type="EnsemblBacteria" id="ACU75929">
        <property type="protein sequence ID" value="ACU75929"/>
        <property type="gene ID" value="Caci_7099"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7099"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_0_11"/>
    <dbReference type="OMA" id="EQCKKCR"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="27284" checksum="BC667F5B36FD3FAD" modified="2009-10-13" version="1">MTTDWRSRKGPIGVLTGAGISTDSGIPDFRGPRGVWSKDPIAELLSTYANYVADPELRQRAWLARRDNPAWQAKPNAAHKALADLEHSGRSVRIITQNIDRLHHRGGSSARKVIEIHGNMFDVVCVQCSYQTTMETTLQRVADGEADPPCPSCGGILKAATIMFGQNLDPASLWQAEQVAEASEIFLAIGTSLRVEPAASLCEVAVSHGADLVIVNNEPTPYDPLATEVIREPIGEAVPRIVAELIAAENGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5G6</accession>
    <name>C7Q5G6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7105"/>
    <dbReference type="EnsemblBacteria" id="ACU75935">
        <property type="protein sequence ID" value="ACU75935"/>
        <property type="gene ID" value="Caci_7105"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7105"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VKDMDMD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="170"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="25686" checksum="BCEAA12FEDD8036A" modified="2009-10-13" version="1">MTHDPISAPTTGPHHQRATIRVILADDQPLIRSGLRVLINDAPDIEVVGEAGTGAEAVRLAAAHTPDVAVMDIRMPEMDGIEATRRITESSDTTRVVMLTTFDDDEYVYAALRAGASGFLVKDMALDSILDAVRVTASGDAIIAPSVTRKLIAEFAIRPDPGATAPRRGDKALLDGVTDREREVLTLVGRGLSNGEIAEELFISAATAKAHVARLFTKLGARDRVQLVITAYEAGLVAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Y9</accession>
    <name>C7Q5Y9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2,5-didehydrogluconate reductase</fullName>
            <ecNumber evidence="5">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.274" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1160"/>
    <dbReference type="EnsemblBacteria" id="ACU70086">
        <property type="protein sequence ID" value="ACU70086"/>
        <property type="gene ID" value="Caci_1160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1160"/>
    <dbReference type="eggNOG" id="COG0656">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_11"/>
    <dbReference type="OMA" id="WRHPDEP"/>
    <dbReference type="OrthoDB" id="1035565at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="18"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="30833" checksum="E3272145A3E3402F" modified="2009-10-13" version="1">MQYITLNDGVQIPQVGLGVWRVSDAEAYGAVTTALEAGYRHVDTAAAYENEGGVGRAIRDSGIPRKDVFLTTKLWNGDHGYDAALRAFDKSLERLGTEYVDLYLIHWPVPEQDLYIESWRALEKIHSDGRARAIGVSNFSAETLERLVKESKKVPSINQIELHPYFCQPAMRQLNEKLGIVTEDWSPLGQGGDLLQEPVLTRIGDAKGKTAAQVVLRWHIQLGDVVIPKSVTASRIVENIDVFDFELTSAEMDEITELRRDDGRIGPDPDHFNYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q620</accession>
    <name>C7Q620_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785411.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1192"/>
    <dbReference type="EnsemblBacteria" id="ACU70117">
        <property type="protein sequence ID" value="ACU70117"/>
        <property type="gene ID" value="Caci_1192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1192"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_13_3_11"/>
    <dbReference type="OMA" id="TQDCDAH"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982809" evidence="7">
        <location>
            <begin position="29"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="86"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="41552" checksum="D7DF685D011DF8B6" modified="2009-10-13" version="1" precursor="true">MVRRTLRKLTVAVLAAGCVMSGTAAARAAQPPAKQISGGAPSPGTAHCTTSLPVPNLPAGSADPDLLWPQQRLGLSQAGVWYLNRGKDVTVAVIDTGVDPANAAFATHAVLPGPSVADPGDTADYDCSGHGTAVAAIIAGKQSGLFGFTGVAPEAQILPIRQTYDPAVSGSSVKLADAIRTAVAAGARVVNISIGVPDDSPQLRSAVQNALASDVLIVAAVGPGPKSYPAAIPGVLAVGAIDARGRVEPRGQGTGVLVSAPGGRMAVPAAGYSDGLTAMEGTDLAAPYVSGVAALVLSDRPTLHNWQVVQRLEATADPPVVNPSSAPGTPSTPDPATGYGVVDPYRAVSQDLPDERRPDPSIGPGVVVSPADAAVPGYDRGASRLALGVSAGAVLVLAAPVAVAARRGRVKGSRAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Q4</accession>
    <name>C7Q6Q4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="6">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793818.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5230"/>
    <dbReference type="EnsemblBacteria" id="ACU74089">
        <property type="protein sequence ID" value="ACU74089"/>
        <property type="gene ID" value="Caci_5230"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5230"/>
    <dbReference type="eggNOG" id="COG2609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020309_0_0_11"/>
    <dbReference type="OMA" id="RPRAHYL"/>
    <dbReference type="OrthoDB" id="49937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041621">
        <property type="entry name" value="PDH_E1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17831">
        <property type="entry name" value="PDH_E1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000156">
        <property type="entry name" value="Pyruvate_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="8">
        <location>
            <begin position="84"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="PDH_E1_M" evidence="9">
        <location>
            <begin position="413"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="789" mass="83387" checksum="50F14AAEDFA20C86" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S4</accession>
    <name>C7Q6S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5250"/>
    <dbReference type="EnsemblBacteria" id="ACU74109">
        <property type="protein sequence ID" value="ACU74109"/>
        <property type="gene ID" value="Caci_5250"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5250"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_9_3_11"/>
    <dbReference type="OMA" id="RMYHHAS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="23852" checksum="5734C67DF1419237" modified="2009-10-13" version="1">MTSTPLALLLDSGGVLMRPIGGRWNPRADFEATVKDHAAQVTDEQLAEAVREGDRFMAAVTSTPDLDDYHRAMLHHIGVEASAELLAALVKDVPPTAVLETFPEVVATLTTLRARGVPMAVVSDAWPNLPDLHAALGMGDFFDAYAISAVLGCHKPDPRMYHHASEALGLAPADCLFVDDAPELVAAAIALGYQGCAMVRDEGDGSAEAEALGVAVISSLTEVLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X6</accession>
    <name>C7Q6X6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795717.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7160"/>
    <dbReference type="EnsemblBacteria" id="ACU75989">
        <property type="protein sequence ID" value="ACU75989"/>
        <property type="gene ID" value="Caci_7160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7160"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="MLTTFEV"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23639" checksum="24B72C32ACAB69F5" modified="2009-10-13" version="1">MTIRVVIADDQPLLRTGFSALVGSAPDLEVVGEAGDGREAVRLAKAAQADVVLMDIRMPVLDGLAATRLITGDEDLAGVKVLILTTFEIDEYVFEALRAGASGFLGKSAEADELLAAIRTVERGDALLSPAATKALISRFLTTPVAPRQLDQAQRGALDALTDRERQITGFVAEGLSNDEIAARLVLSPATVKTHVNRAMVKVGARDRAQLVVFAHRSGLASVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E6</accession>
    <name>C7Q7E6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785528.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70234">
        <property type="protein sequence ID" value="ACU70234"/>
        <property type="gene ID" value="Caci_1310"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1310"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_2_11"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="20547" checksum="EA8B1E82055A50BE" modified="2009-10-13" version="1">MPRLLVITSTTRPGRVGTAVADWVLGLAREHGGFEVELADLAEIGLPFLDEPDHPSEGAYIHAHTRAWSKTVEAADAFLILAAEYNRGITAPLKNALDSLYAEWAAKPVGFVSYGMSSAGLRAVEMITQVAVALGMTPLPDIVTLPLREVQDADGRLIPGERRERGVHALLEELRRYSEALGQLRKPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I9</accession>
    <name>C7Q7I9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_3275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787475.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3275"/>
    <dbReference type="EnsemblBacteria" id="ACU72182">
        <property type="protein sequence ID" value="ACU72182"/>
        <property type="gene ID" value="Caci_3275"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3275"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="TICEPED"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="218"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="516"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="32"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="522"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="582"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="688"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU72182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="855" mass="87377" checksum="19FCBDC9FF5E3F68" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q814</accession>
    <name>C7Q814_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793910.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5322"/>
    <dbReference type="EnsemblBacteria" id="ACU74181">
        <property type="protein sequence ID" value="ACU74181"/>
        <property type="gene ID" value="Caci_5322"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5322"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052806_1_0_11"/>
    <dbReference type="OMA" id="RMSERHQ"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="35773" checksum="A1DA5C2E57F2F03B" modified="2009-10-13" version="1">MSEALYTIGDLARRTGLPVKTIRFYADEGIVPETGRTPAGYRVYDIGAIARLDLVRTLRELGVDLPTVRRVLARETTLAEVAAAHAEALDVQLRTLRLRRAVLGAVAARGATHQEMDLMHRIARMSDLERKRVIEDFIEDTFSGIDANPELVELVRAATPDLPDDATPEQVEAWIELAELTQDPDFRTSVRAMAQYQAAERAEGDTTGLHHELTALVRERITQAITDGIDPQSPAADPIIAELGAQYATTFGKPDDPALRAWLWRRLEVAADPRVERYWRLLAAVNRWPEPETLGPVFEWFQRALRVRMGHLERDGAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q887</accession>
    <name>C7Q887_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795803.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7246"/>
    <dbReference type="EnsemblBacteria" id="ACU76075">
        <property type="protein sequence ID" value="ACU76075"/>
        <property type="gene ID" value="Caci_7246"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7246"/>
    <dbReference type="HOGENOM" id="CLU_2714976_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="72" mass="7579" checksum="A0C11C03A8B8A8EF" modified="2009-10-13" version="1">MEPLIPLARAVASEVDRLGGFPAAVHIDGPRSVVVIEGLAGPETAARIQHALGRVRLRVEADGAGRLRVYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8C5</accession>
    <name>C7Q8C5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7284</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795841.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7284"/>
    <dbReference type="EnsemblBacteria" id="ACU76113">
        <property type="protein sequence ID" value="ACU76113"/>
        <property type="gene ID" value="Caci_7284"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7284"/>
    <dbReference type="eggNOG" id="COG1792">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042663_3_0_11"/>
    <dbReference type="OMA" id="RDMTVLN"/>
    <dbReference type="OrthoDB" id="837894at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="29735" checksum="6CD5A112701D8768" modified="2009-10-13" version="1" precursor="true">MRDDKRTRLLLAVLLAAAFAMITVDARGGPRSPLQPLRSGGEAVLGPVARSVAAAERPVGDFVHGLGHSEQDKKEIARLKTQNAALRVQSETAADVRARAAELDKLLHVATVGGYRTIPARVMSFAPQQQGTWSATIDAGSMDGIKPGMTVLDGEGLVGRTVAVGRDTSTVLLADDPRFIVGVRTPGTGGAGGGQVGLATGGGNGALSVQFFDPQADIPLGTPVLTFGSAGGTPFVPGVPLGTVTSVQPTPGALTRTAIVKPYVAYDGLQTVGVVVEPPRTDPRDALVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D5</accession>
    <name>C7Q8D5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="11" type="ordered locus">Caci_7294</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795851.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7294"/>
    <dbReference type="MEROPS" id="S14.009"/>
    <dbReference type="EnsemblBacteria" id="ACU76123">
        <property type="protein sequence ID" value="ACU76123"/>
        <property type="gene ID" value="Caci_7294"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7294"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_11"/>
    <dbReference type="OMA" id="GFKRQDP"/>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="24066" checksum="61184E59D71CA1A9" modified="2009-10-13" version="1">MNDMQYRGPEHDARYIVPKFSERTSYGFREWDPYSKLFDERIIFLGVQIDDASANDVMAQLITLESMDPDRDISIYINSPGGSFTALTAIYDTMMWVKPDIQTVCMGQAASAAAVLLAAGTPGKRLALPNARILIHQPWSEGGRGDLSDLEIQANEILRMRTVMEQMLSKHSGREPELVHKDIDRDKILSADEAKDYGIIDQVLTSRTESLNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8S2</accession>
    <name>C7Q8S2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1414</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1414"/>
    <dbReference type="REBASE" id="21656">
        <property type="entry name" value="M.CacDORF1414P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70337">
        <property type="protein sequence ID" value="ACU70337"/>
        <property type="gene ID" value="Caci_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1414"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006958_2_0_11"/>
    <dbReference type="OMA" id="CENVRGL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="46329" checksum="07D8626D736DC5C0" modified="2009-10-13" version="1">MHTPADRIPPPRTAATPAAGTSVELFSGGGGLALAMHRAGFQHLMCNEFAPRACETLRMNSEALGRPQLIEGDIATAVTDERLAELTGKVDVVAGGPPCQPFSLGGDHRGHEDRRNMFPQLFRVVRGTRPKAIICENVRGLLRPSFKPYFDYILRELEAPFEQRVDGEVWTEHDERLRKALRGRGGEPSERYVVKAIPVNAANFGVPQVRYRVIIVAFRADLSVAWTPPAETHSQALLELAQSTGEYWDEHPEAPRPDTPGGFVQQRLDGGPEDGGTRRWRTLRDALKDPMPLPEPINGKNRAGFTYHIGIPNARTYKGHTPNRRDWPAKTVKAGVHGVPGGESVIENDDGTHRYMTVRETARVMTFPDTWKLDGPRTEQMRQLGNAVPVLLGNVFADSVAAALAANIEPERRVDERMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X6</accession>
    <name>C7Q8X6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Transaldolase</fullName>
            <ecNumber evidence="6 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tal</name>
        <name evidence="8" type="ordered locus">Caci_3390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the transaldolase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787589.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3390"/>
    <dbReference type="EnsemblBacteria" id="ACU72296">
        <property type="protein sequence ID" value="ACU72296"/>
        <property type="gene ID" value="Caci_3390"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3390"/>
    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050771_1_0_11"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00493">
        <property type="entry name" value="Transaldolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004732">
        <property type="entry name" value="Transaldolase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036915">
        <property type="entry name" value="Trnald_Bac_Plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="39775" checksum="F5353544609AFE93" modified="2009-10-13" version="1">MRTTLQQLAEHGQSPWIHHLTRDWIHDPDHGLPRLIRHGVTGAVANPATLVAALSGTTAYDEQIRTLLPVVEDSNEFHRQLVRLDARDACDLLLETAAGDKPLDGWIGVEVDPRFIDDAAAIVEQARWLSAAVGRPNLLVGITAAGSGLAAIEEATALGLSVLATGVYSPGRYRDTALAYQRGLARLVAAGGDPATVTSVASVPVAALDEKADLRLRAVGRHPELIGTLGMATAKLIRSEYLAFFTGAEWERLAAFGATPQRCLWSGLTVSDGRQPSLRYAEGLIGRGSAALLSRHTAEAFLSRGRVQPTLDYQLTAARRILAAHVKAGVSPKLIVNALEAENVRRGAEAFGDVRALIDYKRAQLGVMAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E2</accession>
    <name>C7Q9E2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5429</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5429"/>
    <dbReference type="EnsemblBacteria" id="ACU74288">
        <property type="protein sequence ID" value="ACU74288"/>
        <property type="gene ID" value="Caci_5429"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5429"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018297_3_0_11"/>
    <dbReference type="OMA" id="QVICVTH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="60708" checksum="14949B4466A0F31E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J0</accession>
    <name>C7Q9J0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ordered locus">Caci_5477</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794065.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5477"/>
    <dbReference type="EnsemblBacteria" id="ACU74336">
        <property type="protein sequence ID" value="ACU74336"/>
        <property type="gene ID" value="Caci_5477"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5477"/>
    <dbReference type="eggNOG" id="COG0072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016891_0_0_11"/>
    <dbReference type="OMA" id="ISYNWLK"/>
    <dbReference type="OrthoDB" id="53568at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14 19" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="43"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="413"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="740"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACU74336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="834" mass="88722" checksum="98DBAD31549E929D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9L4</accession>
    <name>C7Q9L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795911.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76183">
        <property type="protein sequence ID" value="ACU76183"/>
        <property type="gene ID" value="Caci_7356"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7356"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_3_1_11"/>
    <dbReference type="OMA" id="KNMWGLL"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="166" mass="18315" checksum="1A01A903F727C2CE" modified="2009-10-13" version="1">MSEKWTLDPSGHEVAFKNKTFWGLATVRGVFKTVHAEGVLDEDGTGEGVVTVESASLDTGLGKRDTHLRSGDFFDVERHPTFQFVVDRIGPVTTASSETQVRGTLKVRDIVKPLTFIAHAEQRGDSVTLTATIPYVRADFEMTWNQLGMMAGKGEISVKLRFTRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q2</accession>
    <name>C7Q9Q2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795949.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7395"/>
    <dbReference type="EnsemblBacteria" id="ACU76221">
        <property type="protein sequence ID" value="ACU76221"/>
        <property type="gene ID" value="Caci_7395"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7395"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4111">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_3_3_11"/>
    <dbReference type="OMA" id="TYGDPKR"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045830">
        <property type="entry name" value="AraR_wHTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19368">
        <property type="entry name" value="AraR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="27703" checksum="2257B8CC1E17AD82" modified="2009-10-13" version="1">MPQDLDPVYDPADYPPFAVTVDLVVLTVAEQGLSVLAVRRGEPPFADRWALPGGFVKPEESLGDAAVRELAEETGLGLQVAGQDSQGVPDHGVHLEQLASYGAPDRDPRMRVVSVAYLALAPLTSLQEGSEGPFPAAGGDARAAEWLPVAKLPGSEGLAFDHARILADGVERARSKIEYSSLAAAFCPPEFTVGELRNVYEAVWGVQLDPRNFHRKVTGTQGFLVPTGGTTSRQGGRPAQLFRRGTATLLNPPMLRPSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA00</accession>
    <name>C7QA00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785692.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1475"/>
    <dbReference type="EnsemblBacteria" id="ACU70398">
        <property type="protein sequence ID" value="ACU70398"/>
        <property type="gene ID" value="Caci_1475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1475"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_0_1_11"/>
    <dbReference type="OMA" id="MIMAACA"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="19286" checksum="AEF51CB043B11BA5" modified="2009-10-13" version="1">MSESAVEWPAVGLTLRVDGHEYPVPQVWIGDSLLAVLRERLDLDEPRDGCSVGECGSCLVLLDGRPAAACLVPAVAAADRDVRTPQDAAFEIARDAVAASGASPCGFCAPALTVAITDLLRRNADPGPAAIREALAGLVCRCAESGRWIEAVARAKEFGFESDADAGAGIGDSGEIPMLVIDAGDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA84</accession>
    <name>C7QA84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785776.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1561"/>
    <dbReference type="EnsemblBacteria" id="ACU70482">
        <property type="protein sequence ID" value="ACU70482"/>
        <property type="gene ID" value="Caci_1561"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1561"/>
    <dbReference type="eggNOG" id="ENOG50330DC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160524_0_0_11"/>
    <dbReference type="OrthoDB" id="1833635at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="128" mass="13715" checksum="1CE79F0549428AEC" modified="2009-10-13" version="1">MPCHRCGARQTDPVRGASPWRRGVRAGEQVLICPACQRDRDWTSDLAHCAACGSPRLTRALGSTHCKDCGAEDHVTPENSENSQNSANPANPETAPAAEAAPESRTGVTTLSEDVHAALERHFGQRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAS6</accession>
    <name>C7QAS6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5540"/>
    <dbReference type="EnsemblBacteria" id="ACU74399">
        <property type="protein sequence ID" value="ACU74399"/>
        <property type="gene ID" value="Caci_5540"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5540"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_3_11"/>
    <dbReference type="OMA" id="HVSGDYD"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21789" checksum="21037A02BE1DCB33" modified="2009-10-13" version="1">MESIANKILYGAARLLRDSVLPVILSAMPNDVRAARPVLDDTDRAILAVLSADARTPNNAIAEAVGIAPSTCLARIRTLRERGVIRGFHADIDPTALGRGLQAMIAVRLRAHTRERVQEFMRDVPGLPDVVGVWHVAGADDYLLHIAVADSDALRDFVLEHLTTHPAVGHTETSLIFGHLRGAVGATAPVTDQTPIGPLPSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB04</accession>
    <name>C7QB04_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794206.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5618"/>
    <dbReference type="EnsemblBacteria" id="ACU74477">
        <property type="protein sequence ID" value="ACU74477"/>
        <property type="gene ID" value="Caci_5618"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5618"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_4_11"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="32"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="20851" checksum="1FBD7763358E2C47" modified="2009-10-13" version="1">MTYHGIVHAGGPPAVHELAQLIVTKIAVGPHAANCYLLRDRLTGEQLLIDAADDAPVLIQLVNGDLAAVITTHPHRDHWRALAEVAAATGAATMAGTHDTGAIEVPTTVPLADGDKIPLGRSHLTAMHLAGDTPGALALLYDDPKGHPHLFTGDCLTGAEPHAPKPAELLTGALAALPDETWVYPARGNDSTLGAERGGLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB50</accession>
    <name>C7QB50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7516"/>
    <dbReference type="EnsemblBacteria" id="ACU76341">
        <property type="protein sequence ID" value="ACU76341"/>
        <property type="gene ID" value="Caci_7516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7516"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_4_0_11"/>
    <dbReference type="OMA" id="WIRDQFC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983089" evidence="1">
        <location>
            <begin position="39"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="452" mass="47185" checksum="C1FD6B3AB42B3056" modified="2009-10-13" version="1" precursor="true">MRTVTPRTARSLCAVAVAAGVAISGSACSSSSSSSSGASTSKNAAAAGTINVWIRGAGDSPKAYQKIFDAFTAQTGIKVTIGKATLTDFETALTAAASAHQLPDMVVDDAAQMGSFVSQGIVLPVAKSSFTGADQLTDQSWASATDLKGQVYAVPFSAQANVLLIRKDWLDKLGLQPPKSWDDLAKVAQAFTAKDPDGDGKNDTYGLAVPGSTSRGYTSWFWSTFLYSAGGDYLKAGGGKFTATVGSPQAVSSAQFLEDQVCKNKDVQPSALGDDTTATNKAFQTGVAGMYLTGPYAYATMDATAVKGKYIVVAPPTGPDGTAGTLAEGTDIFTMADSKQDEVTKLEEFMVTPDAQKLGMSAVPTATIVRLPVNKTVDASAVHGDDPRWQLAQQVYSSSGHYEYDNAPNWTQLRQKMSDDLNKLLSSCGNVQTAMTSMNADVAALLKQQGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB92</accession>
    <name>C7QB92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796108.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7558"/>
    <dbReference type="EnsemblBacteria" id="ACU76383">
        <property type="protein sequence ID" value="ACU76383"/>
        <property type="gene ID" value="Caci_7558"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7558"/>
    <dbReference type="HOGENOM" id="CLU_705330_0_0_11"/>
    <dbReference type="OMA" id="VDIWVDD"/>
    <dbReference type="OrthoDB" id="1542347at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983090" evidence="2">
        <location>
            <begin position="28"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="38838" checksum="8E7244A2F0105491" modified="2009-10-13" version="1" precursor="true">MPRKQIWSGAVLAAVAASSLTGCSLKASDGTPQSFAQLSALSAPAAIQAADRAVDAHPSAKVHTVLTTATASETSDVTAVFDEHPTVQGTLVEGAGGPSTGGAQSSPAIPIQYADGVMYMKMGAIPQMAAQMDGKPWLKMDLRAMAQDPNTASFGTDVLENTSPSKGLTVLAAAKDLHVVGAEQHGGVQTMHYAGSVNGADATDPNIAGHNGLTQEDADVVGDALGQGVVTKLGYDLWLNAKGQPVAMTFTETTPAGDMTGEIDYSAWGTEAAVTPIPDNQSADFVAMVKSEEAAQGSQDAGRATPSSPASSDGSSTPSSPSAPSTPSSPSTPSTPSTPSTPSVPGTPTPTGTSSSSSTNSTTSSSTTSSSTTSSSSASSSAPSSTSTPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBB1</accession>
    <name>C7QBB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796127.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76402">
        <property type="protein sequence ID" value="ACU76402"/>
        <property type="gene ID" value="Caci_7578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7578"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_1_1_11"/>
    <dbReference type="OMA" id="SERMTTE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="18201" checksum="9233EF96230A0414" modified="2009-10-13" version="1">MSSVSPTDAAATRERRRTMNQITDTFREMSVVMTVLNLRAGEQVGLRDVEMKALDVLMRDGAMSAKALGQRLGMHPATMTGILDKLEKSGWVVRERSPEDRRVVLIQPVRERVGEVVRLFAGMNGTAIELLDRYDTEQLETILGFMNTMVDMAKQASKQWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH3</accession>
    <name>C7QBH3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine_BP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785844.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1629"/>
    <dbReference type="EnsemblBacteria" id="ACU70550">
        <property type="protein sequence ID" value="ACU70550"/>
        <property type="gene ID" value="Caci_1629"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1629"/>
    <dbReference type="eggNOG" id="COG0011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137479_1_0_11"/>
    <dbReference type="OMA" id="AMFTSIE"/>
    <dbReference type="OrthoDB" id="2054097at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="SSF89957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00106">
        <property type="entry name" value="TIGR00106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine_BP" evidence="2">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10046" checksum="BC87F4CC58352010" modified="2009-10-13" version="1">MIIAFSVTPIGAGEGVSEYVADAVRVVRESGLPNSTDAMFTSIEGEWDEVMAVVKAAVDAVAAKAPRVSVVLKADIRAGVTDGLTAKVAAVEEKLAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY6</accession>
    <name>C7QBY6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792334.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3703"/>
    <dbReference type="EnsemblBacteria" id="ACU72605">
        <property type="protein sequence ID" value="ACU72605"/>
        <property type="gene ID" value="Caci_3703"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3703"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_8_0_11"/>
    <dbReference type="OMA" id="QGGWHFT"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982718" evidence="2">
        <location>
            <begin position="37"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="48887" checksum="51308265EE8E6AAB" modified="2009-10-13" version="1" precursor="true">MKSYAQRPTVRRTAALVLVAGLSLSAAACSSSKSGAKGAAAPAGGDGPVTISVPCEPPTSQAGQRKEWLADVATFEKANPTITINGIDTYPCEDTATFTAQMRAGTEPDVFHTYFTDLNQVLDSGQAADITSYVNDTTLPGFKDIAPSALAAVTAGKTLYGLPTGIYTQGLIINRKLFKQAGLDPDHPPTTWADVEKDAKAITALGNGIYGYGEYSAGNNGGWHFSSEVDANGGQMIGSDGTKAAFNAQPATEVLQALHQMRFVDNSMSPTQQLKWGDLQKQMGAGKLGMYVASPDDIYNVIVPQDGGNVDDYGIGPLPSTSGTPAGSLSGGDDVMFNKHDTPAQIRAGIKWIAFSMLTPGQGQFNYARTKADGLPVGFPEPLDWIGDTSAKNETLKAASATVNTAYFKTFVDAHEKGMGEPADAQAVYKTLDATMLSVLNDPNANIPNLLKTAETQVNTLLANAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC71</accession>
    <name>C7QC71_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794248.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5660"/>
    <dbReference type="EnsemblBacteria" id="ACU74519">
        <property type="protein sequence ID" value="ACU74519"/>
        <property type="gene ID" value="Caci_5660"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5660"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_1_1_11"/>
    <dbReference type="OMA" id="GLYRWDM"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18391" checksum="78BEC136E30910AB" modified="2009-10-13" version="1">MSYPSPRYLADQGEVSATFRTADADPELNIGTASRVSLLSTGGTTGGLYGLYRWDMLPGTPTPPKTAASGGGHYHRTFSEAFFILNGTVALYDGQTWRESTAGDYLFVPPGGIHSFANTSGEAASMLVLFAPGAPREPYFEELAAIRGEGRELSPQEWTELYARHDQFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCE4</accession>
    <name>C7QCE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5734"/>
    <dbReference type="EnsemblBacteria" id="ACU74592">
        <property type="protein sequence ID" value="ACU74592"/>
        <property type="gene ID" value="Caci_5734"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5734"/>
    <dbReference type="eggNOG" id="ENOG5032X2I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058994_0_0_11"/>
    <dbReference type="OMA" id="PFQPPMT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027948">
        <property type="entry name" value="DUF4436"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14494">
        <property type="entry name" value="DUF4436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="29417" checksum="2301CC4735889A83" modified="2009-10-13" version="1">MVGAVLIVALATLAGVYLSHLDRGGRHYGFGAGATQVPDRVDVLATINRVDAPRNEASVRVFVSVEGAYAEDDTGVYPKQDVTISTSSLSSGELTFPAGKRIVSQDVRMDLPGGDIADYPFDRYSTTLRFAADVAGKPVPATVAIIDSDPGFVTRETPVGGEPLAPGFDIQLRRTRGTFTMVWLMYVIMWALALSVLTGALVMGHRRLGMVWPGLGWMAASLFALAGYRNTAPGQPPIGCLLDYTVFLWAEALVAFSMVYAVLRGTRVEVAAEAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF2</accession>
    <name>C7QCF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Taurine dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.11.17" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794329.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5742"/>
    <dbReference type="EnsemblBacteria" id="ACU74600">
        <property type="protein sequence ID" value="ACU74600"/>
        <property type="gene ID" value="Caci_5742"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5742"/>
    <dbReference type="eggNOG" id="COG2175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_2_1_11"/>
    <dbReference type="OMA" id="PPFGCVL"/>
    <dbReference type="OrthoDB" id="1742732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000908">
        <property type="term" value="F:taurine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="3">
        <location>
            <begin position="41"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="34675" checksum="3FB0F70B329E5FCE" modified="2009-10-13" version="1">MAPYATLQALLTGRDLAAGPRRGLRRLPEGEESRPYETVTVTPCTRLIGAQISGIDLGEPVAPEVFAELDRALLEFKVLFFRGQSRVTAARHRDFAGMWGELEIHPFLPQGDVAEIVRFEKSEREAGVENVWHADVTWREKPALGSVLRAVEVPEAGGDTCFADMAAAYDCLPEQVKARIEGRVAVHDFTLPFGIGMDPDKLKEMQEKYPAVEHPVVRTHPRTGRRTLFVNAIFTTHIVGLPEQESEELLKVLFRQASVPEYQVRFKWEPGSIAFWDNRAVQHYAVSDYFPRRRVMERAAILGDRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCJ2</accession>
    <name>C7QCJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7631"/>
    <dbReference type="EnsemblBacteria" id="ACU76455">
        <property type="protein sequence ID" value="ACU76455"/>
        <property type="gene ID" value="Caci_7631"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7631"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_9_1_11"/>
    <dbReference type="OMA" id="QIGWMSE"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="21752" checksum="5D8C30CB268EA1A7" modified="2009-10-13" version="1">MTEQKQGSREGVRILPSADVDDRAEIGEGTSVWHLAQVREGARVGRNVVIGRGAYIGPDVPVGDNCKIQNHALVYEPAVLEPGVFIGPAVVLTNDHYPRAINADGTPKSAHDWTPVGVTLREGASVGARSVCIAPVTVGRWALVAAGSVVSKDVPDFALVAGVPAKRIRWVGKAGEPLEDRGDGLFVCPKDGSEYVENDGVLKEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCT9</accession>
    <name>C7QCT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785943.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1728"/>
    <dbReference type="EnsemblBacteria" id="ACU70649">
        <property type="protein sequence ID" value="ACU70649"/>
        <property type="gene ID" value="Caci_1728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1728"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_1_11"/>
    <dbReference type="OMA" id="FGANTYR"/>
    <dbReference type="OrthoDB" id="1306955at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="6"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20844" checksum="381BEC5A21CDF8F8" modified="2009-10-13" version="1">MSATYTFDVFSSLDGFGGSTGDWGGYWGKQGPELLAHRLDVYRGDQRMVFGATTYRDFVGMLAEAGEDSDVRDPWVARMVSLPATVVSSTLSEPLDWPDATVAAGDAVDVVARLKKESAVPLRSHGSLAMNRALMAAGLVDRVQVTIFPVLTGRTGAAPIFQGAEDFDLELIESRTFDGRTQELIYRPTLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCU8</accession>
    <name>C7QCU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1737"/>
    <dbReference type="EnsemblBacteria" id="ACU70658">
        <property type="protein sequence ID" value="ACU70658"/>
        <property type="gene ID" value="Caci_1737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1737"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_884778_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="30847" checksum="AB99896FA0FBA99D" modified="2009-10-13" version="1">MMSPYGMPLSDGGPEGTGGSGNQGGQGGYGGYGGHGPGDGDPGDSGRRRKTLIASALAVVAVVGIGGAVASMNSGSHKPDTASLAGAGASESSSSTPGDGSAVIANGGGKPDGDDMAAASTNGAQGANVPGNPTSTGTPTGGHTGPSTSPGSPSTSHPATSTHPGSTASSHPGTPVVSNPPPSAAKPSAPATTVTVSVPSTDCTYMDLPASKMPQIKQGSTNVNAVKQVQCLLKKSELGIKPLAIDGQWGSDTQSAMTAFQKCNNAPTVHSPGGTPPYPKLSVDGVAGPQTWADLYFWDNQYFNGTSYYCNGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD88</accession>
    <name>C7QD88_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ABC-type sulfonate transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792410.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3779"/>
    <dbReference type="EnsemblBacteria" id="ACU72681">
        <property type="protein sequence ID" value="ACU72681"/>
        <property type="gene ID" value="Caci_3779"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3779"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_2_1_11"/>
    <dbReference type="OMA" id="GAERWAY"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981553" evidence="1">
        <location>
            <begin position="34"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="135"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="362" mass="37293" checksum="9B30EFFB598001D0" modified="2009-10-13" version="1" precursor="true">MRPRHLADRASALRRTAALLTAIATVGGLTACGSSSHPALALTAALPSTVPSGTVLRIGDPAVQIAIQAAGLDKELAADGVTVKWANISGGPDSIKAFRGNQLDCSAVADIPSLFAHWTGTSTQIVFQSVTVDPLAHPVYKLGVAPGKDVKTLADLKGKKIAYSPGQAQGALVLRVLQKAGLTKNDVTLVDLPSTASTYNQALGSHAVDVAPLGTSTIVTYLKQYPGSSAITTGIRDDASTLYCLTSSVKDTAKAAALQEYVAVRTKALLWENAHPDQWAKLYYEQNQGLSAADAQHAVQVKGLAGIPATWTDADARLQATADLLAADQGNAKFDVSTIVDTRFAGVEAAAAGSNVVTGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK3</accession>
    <name>C7QDK3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5769"/>
    <dbReference type="EnsemblBacteria" id="ACU74627">
        <property type="protein sequence ID" value="ACU74627"/>
        <property type="gene ID" value="Caci_5769"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5769"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="YNLAHRH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="45"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="33498" checksum="B5983E38262DD020" modified="2009-10-13" version="1">MMVREATRHQPWYDTKGTASTMSTLPASLPGGTWTLGDMTVTRFGFGAMQLAGPGVMGPPADHDGALAVLREAVELGITHIDTADAYGPHTTNQLIREALHPYPDPLHIVTKVGATRDEQGGWPPARRPDQLRRAVRENLENLGTDTLDLVNLRLGDAQGPVPGSLAEAFETLLELQRQGVIRHLGVSNATPEQVAEARTLAPIVSVQNMYNLAHRHDDELIDELAEAGIAYVPFFPLGGFTPLQSSALTAVAARLEATPMAVALAWLLRRSPNILLIPGTSSVAHLRQNITGAALTLSDDDLTELDKIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDP6</accession>
    <name>C7QDP6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thyA</name>
        <name evidence="8" type="ordered locus">Caci_5812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5812"/>
    <dbReference type="EnsemblBacteria" id="ACU74670">
        <property type="protein sequence ID" value="ACU74670"/>
        <property type="gene ID" value="Caci_5812"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5812"/>
    <dbReference type="eggNOG" id="COG0207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021669_0_0_11"/>
    <dbReference type="OMA" id="KQYLDLC"/>
    <dbReference type="OrthoDB" id="1212177at2"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="17"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="140"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="180"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="277" mass="31229" checksum="7A06A8B89A2311FC" modified="2009-10-13" version="1">MPATHLDTHPETKPDTQYEDLLQRVLTSGTVKADRTGVGTRSLFGHQLRYRLQDGFPLITTKKVHFKSVAYELLWFLRGEGNVRWLQEHGVSIWDEWADAEGDLGPVYGVQWRSWPTPDGRHVDQIAEVLRLLRTDPDSRRIVVSAWNVGELTNMALPPCHAFFQFYVADGALSCQLYQRSADMFLGVPFNIASYALLTHMIAAQTGLAVGDLVWTGGDIHIYDNHVEQARLLLTREARLFPTLELKPADSLFDYSYEDIAVLGYDPHPAIKAPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR5</accession>
    <name>C7QDR5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_5831</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794418.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5831"/>
    <dbReference type="EnsemblBacteria" id="ACU74689">
        <property type="protein sequence ID" value="ACU74689"/>
        <property type="gene ID" value="Caci_5831"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5831"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="SANENFM"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983132" evidence="9">
        <location>
            <begin position="23"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="341"/>
            <end position="587"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="592"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="375"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU74689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="633" mass="67526" checksum="3BE53FA2026B3951" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDV4</accession>
    <name>C7QDV4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5870"/>
    <dbReference type="EnsemblBacteria" id="ACU74728">
        <property type="protein sequence ID" value="ACU74728"/>
        <property type="gene ID" value="Caci_5870"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5870"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041278_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF_2" evidence="3">
        <location>
            <begin position="171"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="2">
        <location>
            <begin position="332"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="43825" checksum="951F5EC79D2252FC" modified="2009-10-13" version="1">MQQIASRNPVDAEIAQLASLMLARTDELTDLVLNRVAEEFPLYIGMIAPDLLHVTIKDHIHFAFEPISRYMPPDARPAAASGRDRAMEGIPLTVIMDGYRIAFGVLWKELATAADSVGLSTKAALRAASEVMDTLDAFTRESSLAYKEELRYQARREEQQRAALVQALLEGRLDDTNVWEAAELLRLPTVGPYVVIAARVPNAGEYGLPHIERELGGMGIDSAWRLMHDVEVGVAHLPRPGDQFDLMVTALAAEGTGRVGVSPPYDHLLSTSQATRLARIAMRGAQERRTVVVFGRDPLSAAAASAPDIMPQVADSVLRGLDGLADEDRTLLLDTFGAWLDSDGSAAEAAKRLFVHPNTVRYRLRRLEERTGRLLANPRAVAELSLAYEIDCALIAEVGTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE23</accession>
    <name>C7QE23_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="3">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">leuB</name>
        <name evidence="5" type="ordered locus">Caci_7787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796336.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7787"/>
    <dbReference type="EnsemblBacteria" id="ACU76611">
        <property type="protein sequence ID" value="ACU76611"/>
        <property type="gene ID" value="Caci_7787"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7787"/>
    <dbReference type="eggNOG" id="COG0473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_11"/>
    <dbReference type="OMA" id="EYDLGAR"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01035">
        <property type="entry name" value="LeuB_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023698">
        <property type="entry name" value="LeuB_actb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="8"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="37532" checksum="CBDD3EC9D48889B2" modified="2009-10-13" version="1">MTAPSSIRLAVIPGDGIGVEVTAEALKVLQAALPQDVKVEGTEYDLGARRYHATGETLPDEVLAELQGYDAILLGAIGDPSVPSGVLERGLLLKLRFAFDHHVNLRPSRLFPGVPGPLREPGAVDFVVVREGTEGPYTGNGGTIRKGTVHEVATEVSLNTAYGVERVVRDAFARAQARPRKKLTLVHKTNVLVFAGSLWSRVFTEVAAEFPEVATDYLHVDAATIFLATQPERFDVIVTDNLFGDIITDLAAAVTGGIGLAASGNLDVTGTFPSMFEPVHGSAPDIAGQGKADPTAAVLSAALLLEHLGRTKASPVLSESARKIEAAVEADLAERAAHDAPRTTSEIGDALAAKAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE89</accession>
    <name>C7QE89_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786074.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1860"/>
    <dbReference type="EnsemblBacteria" id="ACU70780">
        <property type="protein sequence ID" value="ACU70780"/>
        <property type="gene ID" value="Caci_1860"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1860"/>
    <dbReference type="eggNOG" id="ENOG5032YW2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_186753_0_0_11"/>
    <dbReference type="OMA" id="MIVRIMG"/>
    <dbReference type="OrthoDB" id="2029670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="10156" checksum="EA7048D8619EA730" modified="2009-10-13" version="1">MIVRILTEGQLEVPDDTIEELNALDTKVLETCQAKDPEAFRTALDTLLARVREVGTPIPLDRLVESDFVLPMADSTLEEVEAMMSEEGLIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE99</accession>
    <name>C7QE99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uracil-xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1870"/>
    <dbReference type="EnsemblBacteria" id="ACU70790">
        <property type="protein sequence ID" value="ACU70790"/>
        <property type="gene ID" value="Caci_1870"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1870"/>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017959_1_1_11"/>
    <dbReference type="OMA" id="FGLCPKF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="462"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="487" mass="50416" checksum="36F292988535E8FE" modified="2009-10-13" version="1">MTFGWRVAYEGKTPPPGSVVRPDERLSWPRTVGLGAQHVVAMFGATFVFPLVMGLNPQLAIMMSGVATLCFLLIVKNKVPSYLGTSASFVSGVAAIRAQGGDNQDVTGAILIAGGVLLVVGVLVHLLGAQVIHAVLPPVVTGAVVLLIGFNLAPVVADTYWPQDQWIALITMLAAIGIMVGVRGFIGRIAIFVALVFGYVLSWIADQIFGRITSYDPGAGHDTTHWRVNFDQLKAAKWVGFPNKTTGSGAHQVAGWHFPEFKWAFILLVLPAVIALVAENTGHVKAVAEMTGDDLDPYMGRAIAADGFGTVVASTFGGSPTTTYAENIGVMAATRVYSTAAYYVAALVAILFGLSPKFGALVAATPGGVLGGITVVLYGMIGLLGVKIWTENRVDFGNPLNLVPIAAGVIIGIGNTSLKFTDNFSLSGIALGTIVTIVCYHGARLIAPAYLKTAGFGTGSGTAAGPAADADGPPEASGPPGGVQGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEF7</accession>
    <name>C7QEF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786141.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1928"/>
    <dbReference type="EnsemblBacteria" id="ACU70848">
        <property type="protein sequence ID" value="ACU70848"/>
        <property type="gene ID" value="Caci_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1928"/>
    <dbReference type="eggNOG" id="ENOG5033R9Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1222956_0_0_11"/>
    <dbReference type="OMA" id="HDTITER"/>
    <dbReference type="OrthoDB" id="1722308at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="24080" checksum="2EF61BF826A50872" modified="2009-10-13" version="1">MNHESPAAGTTRALIVGRSPSVLVSAVELLREKGYRAEATNQFDRVLEDYDVADLDILVFGGMVPPDTKQHLHDTITERNSQVVFVQGLAGIAGVVAAQVEAAAAAGMPPIGDVSYDQTKRTFRITLAEAEHVSVEALWGTSFTPPEPTSTAAPIFDGELAAGSHEIALPDQVPDVASFAVVRVRDHVRVLTIGAMPQAVARMVPKSAEDRRLPGVATVTTHDPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI1</accession>
    <name>C7QEI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1952"/>
    <dbReference type="EnsemblBacteria" id="ACU70872">
        <property type="protein sequence ID" value="ACU70872"/>
        <property type="gene ID" value="Caci_1952"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1952"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="QAGVAHH"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="187"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="46255" checksum="A7A1E9BC80969092" modified="2009-10-13" version="1">MTLVDRIKEWVRPGTTSRDVVTTLLYLVLLSPAMFVSALHKHVSAETAAALLTTVAIPLLFRSRWPLGAVVGTAAVEVAAMPFVGVPSIPPIACAIALFSFAKRSDRPTTVRVGAVTAVALTALALILRPGMDELAENLGFIAWVGLAVAVGDAARSRRDLFASAMERAETAERTKEEEARRRVTEERMRIARELHDVVAHHITLVNAQAGVAHHLMKTDPSHAYEALERIRDTSRSALDELRATVGLLRASDETAAPREPAPGLGDLDALVESFHHAGLNVVMAGLGADARAPMPAMPALTGLTAYRIVQEALTNTHKHAGSSALARVRVEFAPEAVRIRVDDDGGRGPARSGMGTGHGMIGMQERVKAVGGTFAAGPRAGGGFRVEAELPLPARGAAGVEAGTGGVAVAGAGGTNRGDNPSVVYEKTADRAFGSSAEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEL7</accession>
    <name>C7QEL7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase_M75 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EfeM/EfeO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792516.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3899"/>
    <dbReference type="EnsemblBacteria" id="ACU72787">
        <property type="protein sequence ID" value="ACU72787"/>
        <property type="gene ID" value="Caci_3899"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3899"/>
    <dbReference type="eggNOG" id="COG2822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050342_2_1_11"/>
    <dbReference type="OMA" id="PFYERIE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14656">
        <property type="entry name" value="Imelysin-like_EfeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034981">
        <property type="entry name" value="Imelysin-like_EfeO/Algp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983150" description="Peptidase_M75 domain-containing protein" evidence="4">
        <location>
            <begin position="51"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M75" evidence="5">
        <location>
            <begin position="167"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="410" mass="42434" checksum="40DA455C445C3CDF" modified="2009-10-13" version="1" precursor="true">MRTSSATSARPRAALIAVAAVALTAAGALAGCSSSSSSGSSSPSGGTAKAADSSKPAGDPHKATVTITSAGGCAADKVSFPAGEVTFDITNKDATAVSEVELQSGQRIVGEKENLPPGFSGTFAVTVDAGTYTLYCPGATKENTPITVTGQASTGADTNTSALLANATKEYASYVTAQIGYLLQTSQALQTALQGTDLTAAQQAYMKARPYYEKIEPVAESFTVGTDNLDSDIDARTDDVPADQWTGFHRIEKGLFEDKSLNGLAAYGAGLVRNVQKLQGLTTGLAYKPFELANGAQELLDEVSSSKITGEEERYSHIDLLDFQANDEGAEQAFADLKPALAKIDPTLTSNISDAFTSLDTLVDSYRTGSNASGFALYTSLNDGDKQKLAAAVKAVQEPLSQVASKVAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEM6</accession>
    <name>C7QEM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRISPR-associated protein, Cse2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3908"/>
    <dbReference type="EnsemblBacteria" id="ACU72796">
        <property type="protein sequence ID" value="ACU72796"/>
        <property type="gene ID" value="Caci_3908"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3908"/>
    <dbReference type="eggNOG" id="ENOG5033037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081588_0_0_11"/>
    <dbReference type="OMA" id="RDFAIGH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013382">
        <property type="entry name" value="CRISPR-assoc_prot_Cse2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038287">
        <property type="entry name" value="Cse2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09485">
        <property type="entry name" value="CRISPR_Cse2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02548">
        <property type="entry name" value="casB_cse2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24994" checksum="76C4D27033E77F4E" modified="2009-10-13" version="1">MTTTSATTVNAPAPAGPPPIHELVKEIANAHIRKLQGGYLNDRPEAVAALARIRRGVGKPLHAVPDLWGLEGTDRLYTDIPDRRENERLRAENAVHIAVTLWAVHQQSRRDSPMHVAGGPQLGRAVRALMPGDDIDEPLRRRFVRIGTATSLDTLAQRLRDVVLVLRQHTQAMDYAALAEQIYHWQMPDRRARVRRDWGRNFHARAQQGTPDTQGTEQTKEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEQ4</accession>
    <name>C7QEQ4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3941"/>
    <dbReference type="EnsemblBacteria" id="ACU72824">
        <property type="protein sequence ID" value="ACU72824"/>
        <property type="gene ID" value="Caci_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3941"/>
    <dbReference type="HOGENOM" id="CLU_131550_1_3_11"/>
    <dbReference type="OMA" id="SANNGSC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="2">
        <location>
            <begin position="6"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="64" mass="7158" checksum="6D6C004BC665174F" modified="2009-10-13" version="1">MDQWGAWRKAQASGSGSGCVEMRSHTDGRREVRDSKDPSGSILAFSRFEWQCFIDGAKNGEFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFE3</accession>
    <name>C7QFE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796445.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7897"/>
    <dbReference type="EnsemblBacteria" id="ACU76720">
        <property type="protein sequence ID" value="ACU76720"/>
        <property type="gene ID" value="Caci_7897"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7897"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111226_4_0_11"/>
    <dbReference type="OMA" id="AFLDIDW"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="17703" checksum="75FA81C60C3AE86E" modified="2009-10-13" version="1">MSETATATGLRLVPVTPENFDAAVAVKVRRDQEHLVAPVMKSLAQAYVYGASAWPRLILDGDRVVGFLMAFLDVDWTQGAGATPDLRSGLWRLNIGQSEQQRGHGRFAVEEVAAEIRRRGGTRMFVSYHPGPAGPQDFYLRLGFQETGETTGGQSIAVRDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG00</accession>
    <name>C7QG00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786270.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70977">
        <property type="protein sequence ID" value="ACU70977"/>
        <property type="gene ID" value="Caci_2058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2058"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_4_11"/>
    <dbReference type="OMA" id="QSWCALS"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18554" checksum="CF04FFF5EEDB0FBC" modified="2009-10-13" version="1">MTGTADTKSVDTKSDTQNTTGTAEIGLVHGWYALSLLHGRIESHVERALQARHDLSAREYSLLDVLSYQHDGDGGHLRMNQVAEAVVLSQSATTRLVTRLEDRGLLERYLCPTDRRGIYTNVTPPGLALLAEARPTHDTALREALDNAAADPRLAPLVETVEQINRTTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU3</accession>
    <name>C7QGU3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794702.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6118"/>
    <dbReference type="EnsemblBacteria" id="ACU74973">
        <property type="protein sequence ID" value="ACU74973"/>
        <property type="gene ID" value="Caci_6118"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6118"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090599_0_0_11"/>
    <dbReference type="OrthoDB" id="1622327at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23684" checksum="91DF66594D18F3C4" modified="2009-10-13" version="1">MTYEIPPEAHRLHAEGRSAGSRGDYDRALALLGRAAALAPDWPYPPYDAAFTHLMRGDTRAAQNLYERVANLSPSGFFTCRTTLDMLKREHAGQLAPGFSRAFVQLEWLEDRAEKMRILRSITQRFPGFPPAWKELSLLLEDPQDRLIALDNGLAGDPDPETRTTLLLNKAGLYASVGDVIAATALYAVIADDPDVTPTGAAFARAFRDKQNPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGZ7</accession>
    <name>C7QGZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796572.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8024"/>
    <dbReference type="EnsemblBacteria" id="ACU76847">
        <property type="protein sequence ID" value="ACU76847"/>
        <property type="gene ID" value="Caci_8024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8024"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075826_1_1_11"/>
    <dbReference type="OMA" id="FNWLMPY"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="21178" checksum="4B741CAA06C5A2B9" modified="2009-10-13" version="1">MTRVIAGAARGRRLAVPPGDGTRPTGDRAREGLFSALASEFGGLSGLSVLDLFAGSGALGLEALSRGAEKVLLVEADRRVTKLIAQNIATVDLPGARVVADRAERAVAGEVPKEAPFDLVLLDPPYAVADGEVVTILTALGEGGWLAPDAVAVLERSARDRDFPWPAGYEATRSKSYGEARMNFAVWYVRGAPTTGPLNPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHD5</accession>
    <name>C7QHD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trans-aconitate 2-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.144</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.144" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784369.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0119"/>
    <dbReference type="EnsemblBacteria" id="ACU69074">
        <property type="protein sequence ID" value="ACU69074"/>
        <property type="gene ID" value="Caci_0119"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0119"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_5_2_11"/>
    <dbReference type="OMA" id="YLAFADH"/>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030798">
        <property type="term" value="F:trans-aconitate 2-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023149">
        <property type="entry name" value="Trans_acon_MeTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="38"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29260" checksum="90B3B3404394EB5B" modified="2009-10-13" version="1">MADDIWNAQQYLRFENDRLRPFLDLVTQLDADGDVHTVVDLGCGPGNGTALLVDWWPGARIVGVDSSPAMIEAAQEQAIPGQVEFELGDLRQWRADGKVDVLLANAVLQWVPDHLDLLPDLAAQLAPGGVLGFQVPGNFEAPSHLALAEMKRRWAGRVPDDLQKPASHDPAVYLEKLAESGLEPDVWETTYTYLVPADPDPSVPCGVTEFVRGSALRPAIKALSESDAADFVSEYDTLARAAYPVRELGGHSVQLLPYRRIFAIGRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW7</accession>
    <name>C7QHW7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2223</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2223"/>
    <dbReference type="EnsemblBacteria" id="ACU71142">
        <property type="protein sequence ID" value="ACU71142"/>
        <property type="gene ID" value="Caci_2223"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2223"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_4_11"/>
    <dbReference type="OMA" id="TVCVWTL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="17"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="45401" checksum="1D1AEB5A7A6ACBA5" modified="2009-10-13" version="1">MRVRVLRVLDVGGLPRVFWWVWVSTLVARTGAFVAPFLSYYLTRSLGHSAAFAGFVAALNAGGAAVSAVVGGVLADRVGRRGTLLGALVASAVTLVALGSVHSVGLIAVLAFLAGLANNATRPATGAIIADIVPSGDRGRAYALNYWAINLGFAVAMLSAGAVASHGYSLLFMGDAIANVGCAVVVFFTVPETRPTSVGVAGAGHAGQPERAGTLVDVLRDRIFLGFLGAVLVGAVIYSQAQTVQPIMMGQDGLGPGAYGAVAALNGILIGVLQLPMTSWMRRYTHGSVLAASSFLMGAGFAVPLLISAVGHPMGVYAGSVVVWTIAEIGSTPPQMALGADLAPAHLRGRYQGMSTLAWSVAGIVGPLVGGWALTAIGASAVLWASLLLGAAGVPAWVMLDRRSRTRVATLRAAEAHWEPVLSAIASPEVVSAGVPTSEPEPEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL1</accession>
    <name>C7QIL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794817.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6234"/>
    <dbReference type="EnsemblBacteria" id="ACU75088">
        <property type="protein sequence ID" value="ACU75088"/>
        <property type="gene ID" value="Caci_6234"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6234"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084981_0_0_11"/>
    <dbReference type="OMA" id="WMAKAII"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="22388" checksum="308FB403EAA27493" modified="2009-10-13" version="1">MTTPQAAPATPATPTTPTNPASGRVNQKRRTHAAIVTAAADLMLTGEEVTMPEVAKTALVSEATAYRYFPDLASLLSEAMADTLPHPDQAFATVAGSTDPVERVAAAAEHLARHVLARQGAVRAMIAATIVRPNAAPPRPGLRFGLIDEALRPLAEAANTDQEMLTHLKRDLSIVMGAEALFSLMDLNGLPPEDAVASIVRTATTLTRAAVSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX7</accession>
    <name>C7QIX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8204</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796752.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8204"/>
    <dbReference type="EnsemblBacteria" id="ACU77027">
        <property type="protein sequence ID" value="ACU77027"/>
        <property type="gene ID" value="Caci_8204"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8204"/>
    <dbReference type="eggNOG" id="COG4965">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068419_0_0_11"/>
    <dbReference type="OMA" id="EVDMRQR"/>
    <dbReference type="OrthoDB" id="1538974at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="112"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="31950" checksum="A81C58CA1ACFBC28" modified="2009-10-13" version="1">MDSAVFNPTTFAAIGVGAAVGGGFALLITAIRGFPAKPEQASGRTAADIVKFLSTRAAVAVVAGAVVLAATRWPTAAIAAGVLVFFWNQLFGGLAAERAALARVEALAGWTESLRDTIAGAVGLEQAIPATARAASPAIRENLHTLVDRLRARMPLPQALEYFADDMDDASADLVIAALILNARLRGPGLREVLGALAQSSREEVDMRQRVMAQRSSTRRSVQIVVGVSVAVVLGLAVFNKSFVQPYSTATGQLVLLGVIGLFAAGFFWLRKLSSIETPARFLQRARTVPAHPVPEQRSGDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ29</accession>
    <name>C7QJ29_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784466.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0216"/>
    <dbReference type="EnsemblBacteria" id="ACU69171">
        <property type="protein sequence ID" value="ACU69171"/>
        <property type="gene ID" value="Caci_0216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0216"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023724_0_0_11"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983257" evidence="1">
        <location>
            <begin position="33"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="663" mass="67365" checksum="51320888C826A60C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJH2</accession>
    <name>C7QJH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_2277</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2277"/>
    <dbReference type="EnsemblBacteria" id="ACU71195">
        <property type="protein sequence ID" value="ACU71195"/>
        <property type="gene ID" value="Caci_2277"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2277"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_7_11"/>
    <dbReference type="OMA" id="TMTERFN"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="46"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="381"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="415"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU71195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="638" mass="68184" checksum="C2C1115E45E86F6E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJV6</accession>
    <name>C7QJV6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase molybdopterin binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4330"/>
    <dbReference type="EnsemblBacteria" id="ACU73194">
        <property type="protein sequence ID" value="ACU73194"/>
        <property type="gene ID" value="Caci_4330"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4330"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040538_0_0_11"/>
    <dbReference type="OMA" id="VLQTKWL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="263"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="42468" checksum="FCA2B8C4C441D7F6" modified="2009-10-13" version="1" precursor="true">MSDFGAPRAGRLPSLACMKAFSSGLRSPRLTSQLGVWLGGMFGVCFVTGFISHEIQHPASWFWWPARPVWLYRVTQGLHVATGLASIPLLGAKLWAVFPRLVNLPTVKKWTRVRDWAQLVERVSVLVLIAAALVQVVSGVLNIARWYAAMGFFFTVLHYWTAWIAIGALLVHVGVKLPVVRRALSAPVRPLRKPPTGLTRRGLLGTVAATSAVVTIATVGETVRPLAGVSVLGDRDPRVGPQGLPVNASALAAGVRTVATDPGWRLEVSGPARTVRLSLDDLAAMKQTTATLPIACVEGWSSSADWTGVPLRDLVAMVGGDHGSQVTAVSLQRFSAYASSVVAPPHARDPHTLIALRLRGEPLHVDHGYPCRLIAPDRPGVLQTKWLAQLIVGSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW8</accession>
    <name>C7QJW8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792935.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4342"/>
    <dbReference type="EnsemblBacteria" id="ACU73206">
        <property type="protein sequence ID" value="ACU73206"/>
        <property type="gene ID" value="Caci_4342"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4342"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_1_0_11"/>
    <dbReference type="OMA" id="ISSGWMT"/>
    <dbReference type="OrthoDB" id="1563802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="6">
        <location>
            <begin position="30"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19456" checksum="CFB3E4326DF4E5AF" modified="2009-10-13" version="1">MSTPSGPSSSPSADAFPVPADERSFEDYRPGAVYEFGSVTVSEEEIIVFASRYDPQSFHVDPVAAVQGPFGGLVASGWHTCALMMRQFAEHYLPTAASLGSPGVDEVRWLKPVRPGDRLHLRLEVLDTRLSRSDPRRGIVRTFAELVDELGEPVLSMTVVSLMRSREGAGEQPASPPASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJZ5</accession>
    <name>C7QJZ5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4369"/>
    <dbReference type="EnsemblBacteria" id="ACU73233">
        <property type="protein sequence ID" value="ACU73233"/>
        <property type="gene ID" value="Caci_4369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4369"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031753_2_0_11"/>
    <dbReference type="OMA" id="ATWLSCK"/>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="372" mass="39108" checksum="B6FC8E2396B33D40" modified="2009-10-13" version="1">MRSSALRPFGILPDGTAVDSWRLTDSSGAQATILAYGATLQELTTPDRDGRIANVVLGFSELSDYIERAAYYGCVVGRYANRIAGGTFALDGREIRLPLNDGPRPNTLHGGTPGFGARLWTAPDGIVEVGDANGADGAAGADGAAGTSLTLTRVSPDGEEGFPGELTVSIRYTLAAGRLTLDYRAETTAPTVLNLSNHARFNLAGEGVGNVLDHELTVAADGFLPVDEALIPLDGAAPVAGTPFDFRTPTPVGARLADPHPQLETVGGYDHCFVLRGGRTAVPRPVVTLRDPASGRTMQIATTEPGLQLYLSSELDGTLTGLGGRPYEQYGGIVLETQHFPDSPHRPDYPSTVLLPGRSFTSTTVYAFGVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK10</accession>
    <name>C7QK10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792977.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4384"/>
    <dbReference type="EnsemblBacteria" id="ACU73248">
        <property type="protein sequence ID" value="ACU73248"/>
        <property type="gene ID" value="Caci_4384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4384"/>
    <dbReference type="eggNOG" id="ENOG5033VIT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101335_4_1_11"/>
    <dbReference type="OMA" id="KWEGPSL"/>
    <dbReference type="OrthoDB" id="1735899at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="15994" checksum="6201D66209581021" modified="2009-10-13" version="1">MGLMNGDSAAAHNFALQIDGVQVEYLAEVGALQLEQDVIKHVQNNPQGKPVVRMMPGISQGGTVSVTRGQTQSSSFTNWINESLAGNMGSARKNATIIYMDYMNNPIKRYDLRNAWCCKVETAGTKAGEAQVLTEQVTITFEELVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK26</accession>
    <name>C7QK26_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6246"/>
    <dbReference type="REBASE" id="21694">
        <property type="entry name" value="CacDMrr2P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75100">
        <property type="protein sequence ID" value="ACU75100"/>
        <property type="gene ID" value="Caci_6246"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6246"/>
    <dbReference type="eggNOG" id="COG1715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_786888_0_0_11"/>
    <dbReference type="OMA" id="NSVYPEI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="384" mass="42016" checksum="EABADAF19796E5CC" modified="2009-10-13" version="1">MRNYERAQAAATRASIAEQKAAEREAARLLAEARLAEVEELNANLAAQYSDIDGILASTLEVDDYVDLATLKITTVDHPPFEPGVLAVETQAVPTPQRWYPPVWNEPMPPAGMGAAFGGRKRYEKTVAEARAAFEATYAEWWRADQALQAAYQGELAHRDELEQARKRKLAEAEAKYRDECEARNAQAAARNAELDTLINGLAFDVESAIDEYVGIVLANSVYPEIFPVEHDHAFALHGRELTLTVTVPEPSKMPTVKEYKYIKAHNEIAATLLSAREQKSRFADAVYQVAVRTLHEVFEADRAGKIHSISLTVGVETIDPGTGLLGTIPLVVVAAEREAFTKFDLSNVVPKATLEHLGAALSKSPFDLTPADTAPGVRAIRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK6</accession>
    <name>C7QKK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796830.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8282"/>
    <dbReference type="EnsemblBacteria" id="ACU77105">
        <property type="protein sequence ID" value="ACU77105"/>
        <property type="gene ID" value="Caci_8282"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8282"/>
    <dbReference type="eggNOG" id="ENOG5032SHK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129221_0_0_11"/>
    <dbReference type="OMA" id="WSGLKFV"/>
    <dbReference type="OrthoDB" id="1595974at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15597" checksum="E04ED8E08B6CE52F" modified="2009-10-13" version="1">MTSAQSSGSSGYSGTPLPKKLGIKTGHRVLFHDAPEGFDPQPLPYDVTVETTEDGGAGPYDVIVAFAKDRATLTEDYATLPALLSKSGSLWMCWPKKASKMVTDVTENAVREDALALPIGLVDVKIAAIDATWSGLKLVYRLDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH2</accession>
    <name>C7PVH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784623.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0375"/>
    <dbReference type="EnsemblBacteria" id="ACU69328">
        <property type="protein sequence ID" value="ACU69328"/>
        <property type="gene ID" value="Caci_0375"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0375"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="WFGQASR"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="9"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="31742" checksum="88239AD190E763D2" modified="2009-10-13" version="1">MKAMTATGRTEPSVALTAVDQPQPRPDEALVKVEAYSVNRGETFQLEAPRPGWRPGKDVAGLVVQAAADGSGPAVGARVVGHPPQGGWAEYVAVPTSSLADLPDTVPAATAAALPLAGLTALRLLRVTRAAAGSRVLMTGASGGVGHYFVELAAAAGLEITAVSSSPERGARLLELGAARVVPSIDAAEGPFDIVLESTGGPNLPAALAKLARRGTLIWFGQASRQPATLDFFDFFAGPESATIRHFHYADSDSTYGQDLQTLVRLVAADRLHPEIGLVTDWTGTADVLTLLRDRGVRGNAVLTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVL4</accession>
    <name>C7PVL4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784665.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0418"/>
    <dbReference type="MEROPS" id="S53.008"/>
    <dbReference type="EnsemblBacteria" id="ACU69370">
        <property type="protein sequence ID" value="ACU69370"/>
        <property type="gene ID" value="Caci_0418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0418"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_3_0_11"/>
    <dbReference type="OMA" id="NEFNTET"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982530" evidence="4">
        <location>
            <begin position="36"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="5">
        <location>
            <begin position="87"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="41125" checksum="D22A91D26BA0660D" modified="2009-10-13" version="1" precursor="true">MRTNLRPAHRRAAISLAAAAVLGITAAAVATSANAAGAPAAKSAGPAWSRACDAPAPGMAACDALHVTNVPEHIRALGVTPNATPSGFGPADLRSAYKLPANGGAGQTVAIVDAYNDPNAAADMATYRSQFGLPACTVASGCFKQVSQTGTSTLPANNTGWAGEISLDLDMVSAVAPNAHIILVEAKTASMANLGTAVNEAVKLGAKFVSNSYGGGESSADTGYDTKYFQHSGVAITASSGDGGYGVEYPAASPYVTAVGGTALKKDSSARGWSESVWSTNSTEGAGSGCSAYEPKPTWQKDTGCSKRTVADVSAVADPATGVAVYQTYGGSGWAVYGGTSVASPLIAAVYADAGTPKASVPAANIYSHTSALNDVTTGKTATCTPKYLCTAGTGFDGPTGWGTPNGLAAFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVQ4</accession>
    <name>C7PVQ4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="10">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">alaS</name>
        <name evidence="12" type="ordered locus">Caci_2378</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786589.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2378"/>
    <dbReference type="EnsemblBacteria" id="ACU71296">
        <property type="protein sequence ID" value="ACU71296"/>
        <property type="gene ID" value="Caci_2378"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2378"/>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_1_1_11"/>
    <dbReference type="OMA" id="YHHTMFE"/>
    <dbReference type="OrthoDB" id="91428at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="11">
        <location>
            <begin position="1"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="674"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="889" mass="94785" checksum="B6C706DCB2AD1C24" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVQ6</accession>
    <name>C7PVQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aminodeoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786591.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2380"/>
    <dbReference type="EnsemblBacteria" id="ACU71298">
        <property type="protein sequence ID" value="ACU71298"/>
        <property type="gene ID" value="Caci_2380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2380"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_398327_0_0_11"/>
    <dbReference type="OMA" id="YAGQPQD"/>
    <dbReference type="OrthoDB" id="708179at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="691" mass="72841" checksum="2E268153B6C789DD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVS5</accession>
    <name>C7PVS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786610.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2399"/>
    <dbReference type="EnsemblBacteria" id="ACU71317">
        <property type="protein sequence ID" value="ACU71317"/>
        <property type="gene ID" value="Caci_2399"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2399"/>
    <dbReference type="eggNOG" id="COG1395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118048_0_0_11"/>
    <dbReference type="OMA" id="QGRWKAV"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16837">
        <property type="entry name" value="BldD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038099">
        <property type="entry name" value="BldD-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037664">
        <property type="entry name" value="BldD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19975" checksum="4EC84A7D7E95E022" modified="2009-10-13" version="1">MSTEYAKALGVRLRAIRSQQGLSLHGVEQKSQGRWKAVVVGSYERGDRAVTVQRLSELAEFYGVPVHELLPGTGAPASAHEQGGKLVLDLERLKALPVDQAGPLLRYVGSIQSQRGDWNGRVMTIRGEDLRTLGVIYEMAPSELVKMLTEWDVLNPAAARPYNDEEGDGEAGGFPGGFAEDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW01</accession>
    <name>C7PW01_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase domain protein hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2475"/>
    <dbReference type="EnsemblBacteria" id="ACU71393">
        <property type="protein sequence ID" value="ACU71393"/>
        <property type="gene ID" value="Caci_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2475"/>
    <dbReference type="eggNOG" id="COG0546">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_0_11"/>
    <dbReference type="OMA" id="WDLRPVF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="25402" checksum="DA090C579F7A9BD4" modified="2009-10-13" version="1">MDQPRAMLFDFSGTLMHFESAESWVRAITEAAGIGVDEGEVEHWAARLIEAGAWYGAYPTYVPEHLAALYESRDLDEPHHRACYTGLIRESGWPWPELVEPLYDRSNAPEAWLAYPDALEAVSEAKDRGLATAVISNISFDIRPHLKHAGLLELLDAVVLSYEVGMVKPDPKIFQLACDTLGVDPASAVMVGDHAADGGGSVLGVRTYFVNQVPVQERPDALISVLREVTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW29</accession>
    <name>C7PW29_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4132 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4413"/>
    <dbReference type="EnsemblBacteria" id="ACU73277">
        <property type="protein sequence ID" value="ACU73277"/>
        <property type="gene ID" value="Caci_4413"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4413"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006807_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4132" evidence="2">
        <location>
            <begin position="723"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1001" mass="108326" checksum="A447BE1710EF95CB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWC1</accession>
    <name>C7PWC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPR1/FUN34/yaaH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793098.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4506"/>
    <dbReference type="EnsemblBacteria" id="ACU73369">
        <property type="protein sequence ID" value="ACU73369"/>
        <property type="gene ID" value="Caci_4506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4506"/>
    <dbReference type="eggNOG" id="COG1584">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_3_1_11"/>
    <dbReference type="OrthoDB" id="1399490at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="21452" checksum="2F701D222D01FA7F" modified="2009-10-13" version="1">MSETSNTVTPAPSSSGIIADPAPLGLAGFAMTTFILSVINTNIISEKGGGDVVLGLALFYGGIAQLLAGMWEYRRGNTFGATAFSSFGAFWLSYWAIVHWSSGEDAHKTIGLYLFAWFIFTGYMTVAALRTNGAVLAVFALLTVTFLLLAIGAWQNSTSGPAGFTKIGGFVGIVTALAAWYASMAAVANETHKRQMFPTWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWV5</accession>
    <name>C7PWV5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8389"/>
    <dbReference type="EnsemblBacteria" id="ACU77212">
        <property type="protein sequence ID" value="ACU77212"/>
        <property type="gene ID" value="Caci_8389"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8389"/>
    <dbReference type="HOGENOM" id="CLU_920385_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="30368" checksum="0D704554AB65017B" modified="2009-10-13" version="1">MRAVEERDELEIETRLRTALQARSELVTHSTLRPGIPPNEHTAGVRAKRDAWWSWRRMWVPVTVAAALAGGVVAGAQLPSDSGSSNATVSPGSSGGSTGAPSTGGAPTGSNPTPAQNAGQAGTASNLGTVGFTLADGWQLTSLSATTGCVTLKTRPAPTPVATGAQALPCGVDGIYLASAATAATWPLSTAAKDTGWWPAGAASASAITCPAAASGNSDRVKTSVLLRSSPKYALAGSTTAVYDEWAVTCDTGSGVQPMLWKLNAAPGAPAPTTFAVAAVVSVDPEYDSALLGMVGSLHQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX44</accession>
    <name>C7PX44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784690.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0443"/>
    <dbReference type="EnsemblBacteria" id="ACU69395">
        <property type="protein sequence ID" value="ACU69395"/>
        <property type="gene ID" value="Caci_0443"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0443"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113685_0_0_11"/>
    <dbReference type="OMA" id="LCHAFYG"/>
    <dbReference type="OrthoDB" id="1358723at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="20614" checksum="FC44D959AB854521" modified="2009-10-13" version="1">MSEIPNEPASANRPFTEFLRAHGAADMPHPGGTLLAHLIRVSDRLAEWGVPLAVQVAGLCHATYGTDGFAPSLLDLADRAILVELIGEGAEALVYRYASCDRSATYPRLRGGEQPVFRDRFAGADCQPTGEELRAFLDITAANELDVFRHNAELADRHAPAFYRLLESVRALMSPAAWDAVRGDLGDRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXH3</accession>
    <name>C7PXH3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2508</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786719.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2508"/>
    <dbReference type="EnsemblBacteria" id="ACU71426">
        <property type="protein sequence ID" value="ACU71426"/>
        <property type="gene ID" value="Caci_2508"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2508"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="ACVPASM"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="47567" checksum="9821B036D550E676" modified="2009-10-13" version="1">MRNERTSRALTLGLCGGYFLVLLDVTIVNVALPQIGTGLHAGASGLAWVVDAYTVPLAALLLACGAIGDLLGHRRVVVAGFAGFGAASVVCALAPGLGWLIAGRAAQGVCAALMLPGTLALLADTAPDEAARARAVGLWAAVGGAALPAGPLVGGLLVETGQWRAVFWVNVPVIVVALAAVLWGSQRSRRSQGSYNLASDAGEASAERGVPWSDVPWAGAAALVVMLACAVTAVVQVRDEAGLSAVMLAMTVVAAVAFRFFERRSARPLLQVEAAARRPLAAACAVAGLMNFCVLGSLFLMTQVLQDTDGLSPLRAGALLLPGMLPLPLLGTTAGRLTTRFGPWRTSTVGLFLAAAGFVGIATGIDGPDLLRLLPALAVWGTGLSILTPAIVAAALRTLPAAPGIASGASNTARQTGAALGVAVFSALAGTATANGFVRHAAWLLTASAVAFVAVALISARSTAVAKERAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU3</accession>
    <name>C7PXU3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4540"/>
    <dbReference type="EnsemblBacteria" id="ACU73403">
        <property type="protein sequence ID" value="ACU73403"/>
        <property type="gene ID" value="Caci_4540"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4540"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="MAFGTER"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="390"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="45968" checksum="FD99DA603BB660F4" modified="2009-10-13" version="1">MLRESRAGTSVAMRYVLGRLLGEGATACVYAATDTTLEREVAVKVFRDPDVGQAQAARFPEEIRILTSLVHPHLLPLYDAGQDGDGRLFMAMPLVSGTTLARAIARGPLAPREVKRIGKALADALSHVHVRGIVHRDVKPSNVLLDDDGTPYLADFGFAHAHDGPVLTASDCVVGTAGYLAPEQAAGFAVPPVADVYALGLVLLEALTGERTYRGTPLERAAANALRPPTIPARLGPGWLKVLRAMTAQDPAIRATAGEAKTLLDLGEDELPEVTVSDATMEVAPVIPKSADAPLPPAPDEASAAVKRPASQRRRVRVGAVALTACAVLGFGAGAKVLAHGSEATPTQAPTGSGAGAATPRQIAVTAPPTASTSGHSPVEMPMTVLASAPISDPATPAKRPDAAVVPSHPQQQQQPAAADRQKATPPAKCPPGHKGNGHDKHKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXW3</accession>
    <name>C7PXW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4561"/>
    <dbReference type="EnsemblBacteria" id="ACU73423">
        <property type="protein sequence ID" value="ACU73423"/>
        <property type="gene ID" value="Caci_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4561"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122305_0_0_11"/>
    <dbReference type="OMA" id="KHYAEEK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18130" checksum="4D016BC8F599F5FD" modified="2009-10-13" version="1">MEAYGDDDMTAQYVTLRTMTAEEYRAATEQREAESVRVLSSAMPEELARERVAHGTAKYLPDGLETAGHHLLTAENARGEAVGNAWVGPDPSQAAGTARSAWLYDLNVFADYRRRGYGTAILAAVEKLIAAEGQSTLGLNVVSDNAAAIALYERSGYAVASMVMRKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY76</accession>
    <name>C7PY76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75366">
        <property type="protein sequence ID" value="ACU75366"/>
        <property type="gene ID" value="Caci_6517"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6517"/>
    <dbReference type="HOGENOM" id="CLU_697725_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="42314" checksum="A22A1EEA907C0869" modified="2009-10-13" version="1">MGQFRLKRLLKAAMYVDQHMLGVPADAPETVGLTDVVGEIARAIHVDVPPTVLVSPYAEVAISGDTADDMILYVGAPFLLGLPVVELKAVLAYTMAALGEPHPALADAVVRSAQSFQDWLDLFGATTPLGRRYRKFLDASAEVRTDLARHADRAAAALAGSQKYAQNGLARSKAITEHFVRFAPYYLVTGAEPLQDLYRNWLLAAAQPVPAWAVHLRSLVDPPIPGECVPLVAALNDEDVDILVAAIDVDPDDATGYDYDRIREKILAVAGESLGREATPADVVALVADGRGVELAARWDGLTSAELAAILSKTHGMEQYSAESLTSVSTTGELLEAFIPGLAVRHGYRYDPVLRPGVLVADAQPEIEIFESIGSAVVGDTTTLAELVKQLTENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA2</accession>
    <name>C7PZA2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ordered locus">Caci_2643</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786852.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2643"/>
    <dbReference type="EnsemblBacteria" id="ACU71559">
        <property type="protein sequence ID" value="ACU71559"/>
        <property type="gene ID" value="Caci_2643"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2643"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_11"/>
    <dbReference type="OMA" id="PDEGIQM"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="186"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="90"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="466" mass="52225" checksum="4010281A8A769D3D" modified="2009-10-13" version="1">MPAPVSSDPADLLVIFGITGDLAHKMTYRALYRLERRGLLDCPIIGVAADELSEGELAESARAAIAAGGETIEESVFGRLAKRLTYLHGDVTDAEVYRRLAKKIGRNHRPLFYLEMPPALFGPIVERLDEAGLLAQATVAVEKPFGHDLASARDLNARLRKVLREDQLLRVDHFLGKEPVIELEYLRFANLALAKIWDRDSVAAIQITMAEDFGVQDRGAFYDPVGALRDVVQNHLLQVLALVTMEPPSGPGADDLRDKKAELLKAVRAADPKRCVRGQYEGYTDIPGVAKGSSTETFIALRLEIDNWRWAGVPIFLRAGKELPERLTEVRLLLRHTPPLTFLPSAAQVEQNQIVLRIDPDPGLRLQLAGRNDHSWRSLHLDDRFAQDLGEPAEPYERLLHAALTGDHQLFAREDGVEETWRIVQPLLDEPPKVHSYKRRSWGPAAASRLLRGHPRWQEPWDVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q028</accession>
    <name>C7Q028_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795250.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6675"/>
    <dbReference type="EnsemblBacteria" id="ACU75521">
        <property type="protein sequence ID" value="ACU75521"/>
        <property type="gene ID" value="Caci_6675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6675"/>
    <dbReference type="eggNOG" id="ENOG50342RA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1668458_0_0_11"/>
    <dbReference type="OMA" id="TINASCG"/>
    <dbReference type="OrthoDB" id="1755401at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981359" evidence="1">
        <location>
            <begin position="31"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="14682" checksum="2D9915F3FB4D74DB" modified="2009-10-13" version="1" precursor="true">MHIGKLGISTATVAGLAVAGALVLAPAANAVTPGSATLSFNCGAFGSGTATVTAAQSGTTATFTLTTSAITSPISISANSVSSTLTMAAKAGGTKTYTGHANPAITAGQPISTGPLTGSVAAGDSLSASSLKVVVFGISVTCTATSAQSPGPFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q054</accession>
    <name>C7Q054_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6701"/>
    <dbReference type="EnsemblBacteria" id="ACU75547">
        <property type="protein sequence ID" value="ACU75547"/>
        <property type="gene ID" value="Caci_6701"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6701"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_406937_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="481"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="675" mass="73508" checksum="2014F68476FC8FB8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0F3</accession>
    <name>C7Q0F3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8671"/>
    <dbReference type="EnsemblBacteria" id="ACU77486">
        <property type="protein sequence ID" value="ACU77486"/>
        <property type="gene ID" value="Caci_8671"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8671"/>
    <dbReference type="eggNOG" id="COG0666">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044347_0_0_11"/>
    <dbReference type="OMA" id="FRLDLHR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="49884" checksum="CFAF30EE74A21646" modified="2009-10-13" version="1">MIAAVAERRAVGDWRGACAAADVDVCLRPDSVRRYYGSAIADQVLDALRELSPDLLRWHLPRRGHGVGDLLAGLLVPLAEFSDGTRRLTLAAATPQFALDAGQRVVLVLLGGRDDGATRSVVEAVRLKYPERLSLLRHRMFWSADAAGELAGLCDATPAEREIAWLQDAGRCAEAWQAGGFSLRLPEMRSRARWLAALPIRIAGLAGRVRDALPGVDEAVVRSGVGTLVLSGLRSDAVAVRVAADREALGLPIVPNAVWSRVVDADLLRFGYLGDHELHPLIAAALLASPQRSTPEPDEWLYREVPFIAGPCHGTADDAPALWIDCGPTRHRIAFHDNTWHIPDHSAHPGREALLSRLGGPTNPCQQALNYLSSGRHVIDLAASLLAHGRTTDVHNLLHTHAGARATLTHIPLPTGGTVAQALATHTENTLRHRMTLAAATRTPAPTTRRRTRKGDPARTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Q0</accession>
    <name>C7Q0Q0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PAS/PAC sensor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0743"/>
    <dbReference type="EnsemblBacteria" id="ACU69678">
        <property type="protein sequence ID" value="ACU69678"/>
        <property type="gene ID" value="Caci_0743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0743"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_3_11"/>
    <dbReference type="OMA" id="PMRARNT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="42"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="162"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="855" mass="92751" checksum="90D26FA64A92F5D1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Y0</accession>
    <name>C7Q0Y0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785053.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0824"/>
    <dbReference type="EnsemblBacteria" id="ACU69758">
        <property type="protein sequence ID" value="ACU69758"/>
        <property type="gene ID" value="Caci_0824"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0824"/>
    <dbReference type="HOGENOM" id="CLU_1591589_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="16262" checksum="9E1B99D87FAEAC83" modified="2009-10-13" version="1" precursor="true">MGRKILILAGAVALAAEALGTLIVAAGFYGFVAFGNGVKFGPAGPGLLKIIAIALNLGLCAALLLGAVILVLAAFGMVLNNFMQGLMMAIAALQLFVTIVVTGVTGWTQLFVLGGVFLLLSGALAVAMVTPNAPKPEPGPVDPAPPAGGSSSGAGGPLPGNGAPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q144</accession>
    <name>C7Q144_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2808</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787012.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2808"/>
    <dbReference type="EnsemblBacteria" id="ACU71719">
        <property type="protein sequence ID" value="ACU71719"/>
        <property type="gene ID" value="Caci_2808"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2808"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_11"/>
    <dbReference type="OMA" id="HYDKEEI"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="29429" checksum="09AA15B577DB335B" modified="2009-10-13" version="1">MSHALTIGDFSKATHLSVRTLRHYHQIGLLEPADVDPDTGYRRYAAVQIPAAQVIRRFRALDMPLDDIHAVLSAPDLRSRDQLIAAHLARMEAGLARTQQAVASLRDLLEHGPAPATIGHRIATATPAAAISAQVGVADVLEWYQGALGELRATLTAQGLRPDGPPGGMFADELFAQEYGRATVFFACHGRIRPMGRVTATTVPAADLATIVHAGPHDEIDRAYGTLAAHVADHEVAVDGPLREYYLVGSGDTADAAAWRTEIGWPVFATGTSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q164</accession>
    <name>C7Q164_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2830"/>
    <dbReference type="EnsemblBacteria" id="ACU71739">
        <property type="protein sequence ID" value="ACU71739"/>
        <property type="gene ID" value="Caci_2830"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2830"/>
    <dbReference type="HOGENOM" id="CLU_183695_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10682" checksum="A3C149D2AB8E4C69" modified="2009-10-13" version="1">MNLLAHVFGLDPGYWANFWSGIGSCLGEFTLVGGATALYKRHTCHVNSPRFCWRPGTHPVVGTAFKACAKHHPTVPDRISAEHIADAHAEQAARSRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1H8</accession>
    <name>C7Q1H8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4846"/>
    <dbReference type="EnsemblBacteria" id="ACU73707">
        <property type="protein sequence ID" value="ACU73707"/>
        <property type="gene ID" value="Caci_4846"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4846"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116681_1_2_11"/>
    <dbReference type="OMA" id="IVWRVEG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17193" checksum="2B80477F0796B1A7" modified="2009-10-13" version="1">MDPQGRSEQVSPQVGALAETVMIQVPADPDYLPVIRSASAHLATRLGCTLPEVADVRLAVDEAGGLLLRHTVRELRTADGAAAADGATDAAATDAPDGDLECRFVLDGSALQVVLSRQARDVVAPRKDDFGWTILSALVDDIVWRVEGTAVRVEILKRRAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1J0</accession>
    <name>C7Q1J0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase 15-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793448.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4858"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73719">
        <property type="protein sequence ID" value="ACU73719"/>
        <property type="gene ID" value="Caci_4858"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4858"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010399_3_1_11"/>
    <dbReference type="OMA" id="YAWIRDQ"/>
    <dbReference type="OrthoDB" id="318658at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="DUF5911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5911" evidence="2">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="1">
        <location>
            <begin position="252"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="597" mass="65058" checksum="46EE06C890ED91D1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q225</accession>
    <name>C7Q225_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797286.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8747"/>
    <dbReference type="EnsemblBacteria" id="ACU77562">
        <property type="protein sequence ID" value="ACU77562"/>
        <property type="gene ID" value="Caci_8747"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8747"/>
    <dbReference type="eggNOG" id="COG1652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_300858_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="994" mass="102879" checksum="C56FDC3DCD777BA8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q249</accession>
    <name>C7Q249_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8771"/>
    <dbReference type="EnsemblBacteria" id="ACU77586">
        <property type="protein sequence ID" value="ACU77586"/>
        <property type="gene ID" value="Caci_8771"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8771"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_4_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="104"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="5">
        <location>
            <begin position="407"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="547" mass="56348" checksum="75477EE7EA5768B6" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2B8</accession>
    <name>C7Q2B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0826"/>
    <dbReference type="EnsemblBacteria" id="ACU69760">
        <property type="protein sequence ID" value="ACU69760"/>
        <property type="gene ID" value="Caci_0826"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0826"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009318_1_0_11"/>
    <dbReference type="OMA" id="KTLWVNN"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="46472" checksum="6A43E759D540DB13" modified="2009-10-13" version="1">MTRSTHGGRPSQPAIRMRRAAATLIATGVIGAGVWFATDRGVWSEGGSTGMSGMAGMDSGAGRGRSGSGSGSSAGSSGSALAAAGAPGSASAGSPRSAGALVPAALPGMPGYDPADLYAFDRPGMVSPVIAAALPRVYVPNTESDTVTVIDPSDYRVVETMKVGHEPQHVVPSWDLKTLWVNNDLGNSLTPIDPFTGKPGAPIPVHDPYNLYFTPDGASAVVMASKDMQLVFRDPHTMAIQKILPVPCEGVNHADFSPNGAYFIVSCEFSGQLLKVDTKTRTLLGVLDLPQRGAMPQDVKISPDGKVFYIADMVANGLWTVDGDAFKVTGLIPTGRGAHGLYVSRDSTTMYVSNRGEGTITLFDFATAKPRTKWQIPNGGSPDMGGVSADGKVLWLSGRYNAEVYAISTTDGHLLARIPVGRGPHGLAVYPQPGRYSLGHTGVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2E1</accession>
    <name>C7Q2E1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit J</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 6 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785078.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0850"/>
    <dbReference type="EnsemblBacteria" id="ACU69783">
        <property type="protein sequence ID" value="ACU69783"/>
        <property type="gene ID" value="Caci_0850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0850"/>
    <dbReference type="eggNOG" id="COG0839">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085957_2_0_11"/>
    <dbReference type="OMA" id="WVLPFEA"/>
    <dbReference type="OrthoDB" id="1683794at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001457">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00499">
        <property type="entry name" value="Oxidored_q3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0874">Quinone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="20360" checksum="4110F504349D5283" modified="2009-10-13" version="1">MTTTRALSSTTGVEITFVLVGLLTFGAAVLTVTVRNLVHAALWLVVALGGLAGCYLLLAAEFVAWVQVLIYVGAVAVLLLFGLMLTRAPIGRTTELDSGNRWAAAVVGLATAGVLVTVIGDAVRTTWFDPRRNVVNGTAKAVGSSLFRYWVLPFELLSVLLLAALVGAIVLSRRDVSADAEGAPATPPRATEAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2K0</accession>
    <name>C7Q2K0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69842">
        <property type="protein sequence ID" value="ACU69842"/>
        <property type="gene ID" value="Caci_0910"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0910"/>
    <dbReference type="HOGENOM" id="CLU_3341847_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="37" mass="3743" checksum="AFCC91D20AD163AA" modified="2009-10-13" version="1">MEPIAAPPDSASGQTLPVATPATSMYGKNVLATLNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2Z2</accession>
    <name>C7Q2Z2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2975"/>
    <dbReference type="EnsemblBacteria" id="ACU71884">
        <property type="protein sequence ID" value="ACU71884"/>
        <property type="gene ID" value="Caci_2975"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2975"/>
    <dbReference type="HOGENOM" id="CLU_2631688_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="8482" checksum="D13AB19773F6B213" modified="2009-10-13" version="1">MLGLVEDPRDRRWNERTGGQRFCDQILADSPLAAEDVAMDKARSEGGRLLVCAVFDGARQRADALYGKFANPDVVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3T6</accession>
    <name>C7Q3T6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_hydro_114 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8881"/>
    <dbReference type="CAZy" id="GH114">
        <property type="family name" value="Glycoside Hydrolase Family 114"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77694">
        <property type="protein sequence ID" value="ACU77694"/>
        <property type="gene ID" value="Caci_8881"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8881"/>
    <dbReference type="eggNOG" id="COG3868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051214_2_0_11"/>
    <dbReference type="OMA" id="CYVNGFQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_114" evidence="1">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24785" checksum="075EB2924002A67A" modified="2009-10-13" version="1">MKWDYQIGGAYAPPSGVRIVSRDSSASPAPGLYNICYLNAFQAQPDATGWWQSNHPDLLLKTSSGAPVIDENWNEQLLDVSTDAKRTAIAQIEGGWIASCAAKGFQAIEPDNLDSYSRSQSLLTADDDVALATQLARLAHAKGLAIAQKNTTEFLPRAHQIGFDFAVSEQCGKYGECGGYASTYADHVVDVEYDDAGFTAACHAYAGKIAIVDRDQDVSPAGSSSYVYKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Z6</accession>
    <name>C7Q3Z6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8941"/>
    <dbReference type="EnsemblBacteria" id="ACU77754">
        <property type="protein sequence ID" value="ACU77754"/>
        <property type="gene ID" value="Caci_8941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8941"/>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024859_2_0_11"/>
    <dbReference type="OMA" id="CHPIEWL"/>
    <dbReference type="OrthoDB" id="260566at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="505" mass="54368" checksum="E798C671C693E010" modified="2009-10-13" version="1">MALTNKSKKTRLPEVDFASLLAPASDTAQQSAGTATSTTDSKKRKVPADPTPPRRGYARKFAGRAPKTPPIPVFRSSTGQFSGLYPWLYGQSMPPVGVYIGVDCLTGGAFSCHPIEWLHSGLITNPNMLITGVPGAGKSAAIKSLAMRLMAYGVKTFVLGDIKNEYAALSRALGVEPVELGPGLGARLNPLDAGPLGMNLPADPELLRERLEEIHRRRITLLASLVVMRLGRALTPTEEAAFSLAIKQASGEAAGNRLIDPTIPQVWALLRDPLPEMAEELRVRDGDVDELREMIRPAVDALGNMVQGSLSGLFDGPTTVGVDFSAPIQTVDLSRIDGRGDETVAMTLACVSSWGQAAIDEPGGPVRLVVRDELWRAMRVPAMIRKLDSDLRLSRAQGTIQVLSTHRLADFEAVGAAGSEEVTIAKNLIASCDVRICLRQDTAPLAMTREAIGLTDTECAHIASWSGEHRGRAVWKVGRSASHVVQTVLTPLERQLYHTNERMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q421</accession>
    <name>C7Q421_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8966"/>
    <dbReference type="EnsemblBacteria" id="ACU77779">
        <property type="protein sequence ID" value="ACU77779"/>
        <property type="gene ID" value="Caci_8966"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8966"/>
    <dbReference type="eggNOG" id="COG3423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059166_0_0_11"/>
    <dbReference type="OMA" id="CEVRLHD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="28294" checksum="75AC341820A028CD" modified="2009-10-13" version="1">MNERLRSALVRTGVTTGELAAACGVDPKTVDRWINTGRRPHARHRFTAAQCLGIDEVELWPIERRDDSTLPSAGSELASIYANRASVPRQLWLDLLEGAAKHIDVLVFSGTFYAQSNPHVARMLLARAQAGTSVRLCFGDPAGESVAIRGREEGIGDTLAAKIRASLTYYRELLSVPGCEVRLHDTTLYASLFRYDDELLVNPHIFGQPASANPLLHLRRSDGGEWFELYAASFDTVWNGARPWAPGEEGHRRGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4I3</accession>
    <name>C7Q4I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D12 class N6 adenine-specific DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787245.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3043"/>
    <dbReference type="REBASE" id="21662">
        <property type="entry name" value="M.CacDORF3043P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71952">
        <property type="protein sequence ID" value="ACU71952"/>
        <property type="gene ID" value="Caci_3043"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3043"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_1_1_11"/>
    <dbReference type="OMA" id="SRQIFEW"/>
    <dbReference type="OrthoDB" id="1206955at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="30085" checksum="F393F65BB71D436F" modified="2009-10-13" version="1">MPPFSYFGGKSTLAPVIAGLLPAHGHYVEPFAGSLAVLLAKAPSRMETVNDLDGGLMAFWRVLRDRPADLERVCALTPHSRAEYLDAYRTDDAPDDLERARRIWVQLAQGRAGTRRPTGWRHYQESAGYSTSMAGYLAGYVGRMAPTAARLAQVSLECRPALEVIEAYGRHADVLLYVDPPYLAGTRNGTNYLHEMPHKDDHRKLAAALNACQATVVLSGYGSPLYDALYDGWDRHEISAMTTQGGTHGRRTEVLWSNRPLEVQQGLFEVAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4N3</accession>
    <name>C7Q4N3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787295.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3093"/>
    <dbReference type="EnsemblBacteria" id="ACU72002">
        <property type="protein sequence ID" value="ACU72002"/>
        <property type="gene ID" value="Caci_3093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3093"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="361" mass="39226" checksum="9836990A9E2D560E" modified="2009-10-13" version="1">MATVDFIRASCTYPEGKRKAVDNLTLSVGDGEFLVLLGPSGCGKTTALRMLAGLEEVQTGQVLVDGQDLEGMPPGDRDLAMVFQSYALFPHMSVARNLGFRMELAGAPPSAVSRRVRRIAAELNLTDRLDRLPKTLSGGEQQRVAIGRAMVREPRVFLMDEPLGALDAKLRTTARAKIAEMQRKSGITTLYVTHDQVEAMAMGDRIAIMNRGMLQQVDTPRQLYDHPVNEFVAGFVGSPAMNLVPGTYKHGWALIGESDVFEVPVEVSQPLTSPSVLVGFRPEHAKFAAPGSGIYAIVGLVERLGHTAYAHCEMGIGRGRRTVIVRCDEYDAPRPGAHVGVVPDPREIHLFDGESGLRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4T8</accession>
    <name>C7Q4T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793615.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5026"/>
    <dbReference type="EnsemblBacteria" id="ACU73886">
        <property type="protein sequence ID" value="ACU73886"/>
        <property type="gene ID" value="Caci_5026"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5026"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="RWRILRS"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="31502" checksum="62033465BAFC6762" modified="2009-10-13" version="1">MTSPALRQRGESALGAIAVLALGLYALFIVVPVIMSAWKSLTDENPLLAHAKFVGVSNYTDMLHDDALTASLTFTLVTALTVTLVANVAGIGFAMLLNKTSLSFRMMRTVAFLPQVLSGVIVGFVWRYILAQDGILNHLLLSAGIIGRPITWLGSPHLAMFSVGLVAAWVLTGFTTVVHLAALQSVPVELYQAATVDGAGRWQRFRQITLPMVAPGTTISVTISLITTLKLYDIIAALTSGGPANSTQSTALYIVNLAFTDDRFGYASAVAMLLLVVSAAIALSVTGLLRRREVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q529</accession>
    <name>C7Q529_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793706.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5118"/>
    <dbReference type="EnsemblBacteria" id="ACU73977">
        <property type="protein sequence ID" value="ACU73977"/>
        <property type="gene ID" value="Caci_5118"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5118"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="RYTGEQP"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="32067" checksum="C546BDDE58765224" modified="2009-10-13" version="1">MNSSDTATAPAPGGTATLAGHQVARIGFGVMQLAEHRPGRQPIDRDAAIAILRTAVASGINHLDTADFYGTNAANANDLIRAALHPYPESLVLATKVGAERDAAGALVPAQRPEQLRAGVEANLARLGAERLAVVNLRRVDAAPGIIAEGDQIVDLDSQLAELVALRDAGKVDGIGLSNVSVDQLRQALPAGIACVQNSHSPVDRAAEPVLDLCRKHDIAWVPFCPLGSAFPQWPKVADQPAVRDAAEALGVTSIQVGLAWHLAHYAHTLLIAGTADPAHLAENIAAGDVRLDSGTRAALDAITVPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J4</accession>
    <name>C7Q5J4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797529.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77805">
        <property type="protein sequence ID" value="ACU77805"/>
        <property type="gene ID" value="Caci_8992"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8992"/>
    <dbReference type="HOGENOM" id="CLU_929676_0_0_11"/>
    <dbReference type="OrthoDB" id="2185906at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="32805" checksum="7F88CBF466E4905B" modified="2009-10-13" version="1">MNTDEAFGHAFTAGHDGNHCTCGEHRFAAIHNPERYPFTPELHDSAEDYADVRRHWASPWQLRAELTSEAEQLRWRTIALMTAPDGEPVEDYDWHAQHGGANEPHICHRALWQSNSETIERVLCDAGANFSVWRGIFTYDASHGPTLEAVAALETSLAHYPSLDDARLCQLEQDAACAELLRGWKVPEDLVQAVLTGLGERGCSLCPECESWPVDDILAEHGVVDCAAECGGQVRSRESAPLCHDCAEAEAGPGCDCVTVMVNSKRPSGAAPTRADIFIVRVNCNICYTYVLPHAGIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5R7</accession>
    <name>C7Q5R7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1088"/>
    <dbReference type="EnsemblBacteria" id="ACU70014">
        <property type="protein sequence ID" value="ACU70014"/>
        <property type="gene ID" value="Caci_1088"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1088"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_12_1_11"/>
    <dbReference type="OMA" id="GELENRH"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="4"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="8707" checksum="88DEF74BEC21ECF2" modified="2009-10-13" version="1">MSVELTSNDLATLLKQKAGVTIDPIDLDRPGATFEDFGVDSLGLLAVVGELENRHGLSMTAAESAKSSAEFLNTVNLSLKKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q694</accession>
    <name>C7Q694_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_3193</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787393.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3193"/>
    <dbReference type="EnsemblBacteria" id="ACU72100">
        <property type="protein sequence ID" value="ACU72100"/>
        <property type="gene ID" value="Caci_3193"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3193"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036138_6_0_11"/>
    <dbReference type="OMA" id="VVTSTTW"/>
    <dbReference type="OrthoDB" id="524437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU72100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25585" checksum="3065BFFB1E80B1E5" modified="2009-10-13" version="1">MPFSSLLTPAIVAAYHAVTGLSVLLVPVLGGLGPAVAIVMFTAAVRLCLHPLNRAQMNSQLASQEQRTALAPAVQKLQRKYKKDPARAQRETLELYRANGVKLAPGIGLGLVQIPVFFVVYRLFVSPTIGGHHNGLLSDQLFGVGLGSHFRDAFSGSSALLGHVAVFAVLIAALAVLATWSSRRMRAGAAATAKLMALMPYLTVLSAVVLPLASGLYAATTTLWTLVERRRMTVPAAPAAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B5</accession>
    <name>C7Q6B5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787414.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3214"/>
    <dbReference type="EnsemblBacteria" id="ACU72121">
        <property type="protein sequence ID" value="ACU72121"/>
        <property type="gene ID" value="Caci_3214"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3214"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1003589_0_0_11"/>
    <dbReference type="OMA" id="SLWGYGG"/>
    <dbReference type="OrthoDB" id="2035522at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="152"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="277" mass="28574" checksum="A5951744F6DB38F6" modified="2009-10-13" version="1">MYTAVNVITLAVHDLDRSVRFYGEGLGCQVERRDEGGAVVRLGGPEMPRLELRPWDDLAGVVGSAPETDGFRGFMISAIFPTAQAVDNLLDAAVRAGGTLVKPGKGAAWGYAGHFADPDGHAWKAVTSGSPLLAKFKRSHPAPAAGPALAPQEVAVTLAVPDMKAAKHFYTAGLGYEVDKAFGKFAKFKPTPGAATLSLYTRDALATDAGVDAAGHGFRGYALTFQAPTEAGVDAVTLASTTAGARVVSGPATRPGSGYSTVFLAPDEAAWSAALTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6M8</accession>
    <name>C7Q6M8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793792.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5204"/>
    <dbReference type="EnsemblBacteria" id="ACU74063">
        <property type="protein sequence ID" value="ACU74063"/>
        <property type="gene ID" value="Caci_5204"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5204"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_7_3_11"/>
    <dbReference type="OMA" id="VTGYCIG"/>
    <dbReference type="OrthoDB" id="1889569at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="16"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27852" checksum="517206A545DE621D" modified="2009-10-13" version="1">MPTAEFEIPTLDGQADAFAAFPDGGERHPGVLLYMDIFGIRPELERRARELAVHGYYVLVPNVFYRHGPAPLIELPDFVGEEARPRAVAQLMPVLQAHTTDRILRDAEAYVRFLTSRPEVSPGPIAVVGYCMGGRLALRTAAAHRDQVAAVAAFHAGKLLSDAPDSLHLDVIPAITADIHLGHAATDMEPEAVRELNRVLDGTGVSYTSEIYPDTIHGFTMSDTTAFNPAGLEQHWDRLLSLLAGAFPGSDPATAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6R2</accession>
    <name>C7Q6R2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793826.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5238"/>
    <dbReference type="EnsemblBacteria" id="ACU74097">
        <property type="protein sequence ID" value="ACU74097"/>
        <property type="gene ID" value="Caci_5238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5238"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033532_3_1_11"/>
    <dbReference type="OMA" id="TEAFSWL"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
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    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="40299" checksum="B0876AEFACA12EC7" modified="2009-10-13" version="1">MGYFALLRLPFIARLLSGSLVGRLPGGMSILMIPLALRRSGMDYGFVGIASGALAVSTAIGGPVLGRLVDRVGQVRVLVPAAAASGVGFAILAVAPGNRLSVLVGVVLAGAAAPPLEPCIRILWPSLVPAEGLASAYSLDSAAQELIFVSGPLVVAGCVAWAAPVAALWLGAALGAVGVLVVATSKPVREWRPEVREAHWLGPLRSPGLVVLLTSLIGLGIAIGTLNVVLVDYAEHHKFPGGAGTLMAINAFGSLIGALVYGARKWPGTATGHLLTLRVGLGAAYALLLLVPAPPLMVAIMVVSGVCFAPSLTVLFMLTGELAPAGTATEAFAWLITLFNVGAAAGAAISGFVIAHAGLSPAAVTAVAGIAAAVLVQLAGRRYLHQSEPEGPVETPVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7M8</accession>
    <name>C7Q7M8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sensor with HAMP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3314</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787514.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3314"/>
    <dbReference type="EnsemblBacteria" id="ACU72221">
        <property type="protein sequence ID" value="ACU72221"/>
        <property type="gene ID" value="Caci_3314"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3314"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002554_3_1_11"/>
    <dbReference type="OMA" id="DNLATRM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982997" evidence="5">
        <location>
            <begin position="34"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="656"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="737"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="850"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="855"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="880"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="944"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1000" mass="103529" checksum="15BA525A2217711B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7P0</accession>
    <name>C7Q7P0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemerythrin HHE cation binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3326"/>
    <dbReference type="EnsemblBacteria" id="ACU72233">
        <property type="protein sequence ID" value="ACU72233"/>
        <property type="gene ID" value="Caci_3326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3326"/>
    <dbReference type="eggNOG" id="COG5592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079417_6_2_11"/>
    <dbReference type="OMA" id="IESHMDH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="2">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="21833" checksum="EC294C246060C04F" modified="2009-10-13" version="1">MSATDRRDVIDVLTGEHRAVEALFQRLETGGGGPDGSRKSLVDALALELAWHAAAAQRYLLPLARRTLPDGDALADRHTAEHLTVEHMVRDLEAKDPSDARFEPLLAQLVAAARGHIEHEEQITFVELTRECDRGELLAAGEEMAAARRRAEAEAASATIPAQARSDAAGPGSVTTASTTAASASTTATPTPAPSVVDRVRAALFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z7</accession>
    <name>C7Q7Z7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative chorismate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793893.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5305"/>
    <dbReference type="EnsemblBacteria" id="ACU74164">
        <property type="protein sequence ID" value="ACU74164"/>
        <property type="gene ID" value="Caci_5305"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5305"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133313_0_0_11"/>
    <dbReference type="OMA" id="WLVWHLT"/>
    <dbReference type="OrthoDB" id="1717097at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18441" checksum="8AA72D706F425D11" modified="2009-10-13" version="1">MTGQDLLVDAFGRVHESVHAAVAGLTLEQLHRRLDGDANPVGWLIWHLARVQDDHVADVAGLEQAWTSQGFDAKFGSPYPAADVGYGQSSGEVGKLNVPSIEVLTAYHDAVHELTVGYVAGLTDDDFDRVVDTRWDPPVTLGVRLISVVSDTMQHVGQAAYVRGILLRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q875</accession>
    <name>C7Q875_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795791.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7234"/>
    <dbReference type="EnsemblBacteria" id="ACU76063">
        <property type="protein sequence ID" value="ACU76063"/>
        <property type="gene ID" value="Caci_7234"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7234"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_3_0_11"/>
    <dbReference type="OMA" id="VDEFTGH"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982890" evidence="1">
        <location>
            <begin position="33"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="38"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="270" mass="27692" checksum="08D8E7C752810522" modified="2009-10-13" version="1" precursor="true">MFKTHLSRGLLSVAAAVTAVVTLLGANASATAADHYVALGDSYSSGVGAGSYISSSGSCDRSTNAYSQLWANSRHPASYVSVACSGATTQDVLNNQISALSSSTTLVSITIGGNDVGFSSVMETCVLDSSSTCLNAINAAVAQAKTILPGRLATTFAAIRSAAPSAHVVVLGYPELYDLGHSWYCPGLSGTDRTALNNAADLLDTQIAAAAANAGDTFADVRSRFHGHELCDFFNEWLHSVDVTDVGDSYHPTASGQSGGYYAAFSAVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8C9</accession>
    <name>C7Q8C9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7288"/>
    <dbReference type="EnsemblBacteria" id="ACU76117">
        <property type="protein sequence ID" value="ACU76117"/>
        <property type="gene ID" value="Caci_7288"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7288"/>
    <dbReference type="HOGENOM" id="CLU_129305_1_1_11"/>
    <dbReference type="OMA" id="LWWASVH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025327">
        <property type="entry name" value="DUF4233"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14017">
        <property type="entry name" value="DUF4233"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="13261" checksum="CA82342455CC5E50" modified="2009-10-13" version="1">MMVRRMAASVLCFEVLVILFFALVAMKLSDLGTGTVWAICGPGMVLAALLCGMLRKQWAYSLGWVLQAALVVAGFVITDMFFIGGGFALLWYWGLRAGRQIDAEKAAAYAAYEAAQAQAAGAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8D4</accession>
    <name>C7Q8D4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpX</name>
        <name evidence="9" type="ordered locus">Caci_7293</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7293"/>
    <dbReference type="EnsemblBacteria" id="ACU76122">
        <property type="protein sequence ID" value="ACU76122"/>
        <property type="gene ID" value="Caci_7293"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7293"/>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_8_2_11"/>
    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="125"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="48467" checksum="DC3834EA67FEEBB9" modified="2009-10-13" version="1">MARIDNADLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEEPGEPAAARGLAELPKPKEIYDFLDEYVIGQENAKKSLSVAVYNHYKRVQAGDYQRERGGRRGEQIELAKSNILLLGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDIKKAETGIIYIDEIDKIARKAENPSITRDVSGEGVQQALLKILEGTVSSVPPQGGRKHPHQEFLQIDTTNVLFIVAGAFEGLDKIVDSRVNKRGMGFTAQLRSRYDVDTTDVFADVLPEDLLKYGMIPEFVGRLPVVTSVHKLDRAALVRILVEPRNALIKQYQKLMELDGVELVFEDDAVEAIADQAILRGTGARGLRAIMEEVLMSVMYEVPSHSDVGTVVITGEVVREHVLPTLVPRDQQFRRTGTQQNLTERRERSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8E9</accession>
    <name>C7Q8E9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795865.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7308"/>
    <dbReference type="EnsemblBacteria" id="ACU76137">
        <property type="protein sequence ID" value="ACU76137"/>
        <property type="gene ID" value="Caci_7308"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7308"/>
    <dbReference type="eggNOG" id="COG1746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_962831_0_0_11"/>
    <dbReference type="OMA" id="FYLEMRA"/>
    <dbReference type="OrthoDB" id="1258110at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31327" checksum="3D525931465354DE" modified="2009-10-13" version="1">MASDATEGFNTCLRWLTPSDAERSKASTHRAGIEAKLSSKFGLYRMFESGSFSNGTGVSGRSDTDLFASLKSSKPSLGSSSLSAVRYALLERFPSTSITVRTPAVVLNFGNGYERVEVIPAYAVGTTNGFTKYSIPGVTSDWMESTPQAHLAYVNGSNAKPSQGNAKALARLLKAWKYYQNVPISSFYLEMRAAAYTRTQSSIYYWMDIYFLLSSLQTTSLAAMNDPTGTTGSIRPCSSDATKQVALSKLDTAVTRAKKAFDAAKDGKMKVAFDNWDLLFGGNFPAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H7</accession>
    <name>C7Q8H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7338"/>
    <dbReference type="EnsemblBacteria" id="ACU76165">
        <property type="protein sequence ID" value="ACU76165"/>
        <property type="gene ID" value="Caci_7338"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7338"/>
    <dbReference type="eggNOG" id="ENOG5033I7F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1861608_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982897" evidence="2">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14463" checksum="5EF1F5CF557FF386" modified="2009-10-13" version="1" precursor="true">MKPPTTPEARTRRALRTATLGSLAAVPLLLASPAFALHRDAGDDPGQGMSAVATILVYIGIPAAVFCVIALLVLAPSIARGNRYRPHQLSWWASPVWFGGPREEHGGSGERALTGTSLKELTAYSEAQTEGGASARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8J6</accession>
    <name>C7Q8J6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ordered locus">Caci_1338</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785555.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1338"/>
    <dbReference type="EnsemblBacteria" id="ACU70261">
        <property type="protein sequence ID" value="ACU70261"/>
        <property type="gene ID" value="Caci_1338"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1338"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_6_1_11"/>
    <dbReference type="OMA" id="WDEGPFF"/>
    <dbReference type="OrthoDB" id="1409413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
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        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
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        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="8"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="342"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU70261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="494" mass="54175" checksum="DC4208C3D3EE1A6D" modified="2009-10-13" version="1">MLNTDKPVRVRFPPSPTGDPHVGMVRSALFNYAFARHYGGTFVFRIEDTDAARNTEESYNALLATMRWMGFDWDEGPEVGGAYGPYRQSERMGIYADIAGKLLDGGHAYRCYCTQEELDAANEKAKAEKRAPGYAGTCRDLTPEQIAAHEAAGRTSVLRFRMPQGTLTWNDLVRGEISFDTANVPDYVLVRADGSPLYTLVNPVDDALMRITHVLRGEDLLSSTPRQLPLHAALIELGLAETVPVFGHLPYVMGEGNKKLSKRDPEASFSFYVKEGYLPEGLLNYLALLGWSPGGDKEFFSPQEMYAAFDGSRINANAARFDLKKCQAINGDHVRALAPEDLAQRIVPFLAEQGLVSDPPQPDQAATLAAAVPLIQERMVVLRESVDMIGFLFVPEHAFTVDPADAAKALTEDAKPVLEAAAKALEALPQWTTAAIDAALRETLIDGLSLKPKNAFTPVRVAITGRRISPPLFESIELLGRDRTLRRLNAALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8P3</accession>
    <name>C7Q8P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1385"/>
    <dbReference type="EnsemblBacteria" id="ACU70308">
        <property type="protein sequence ID" value="ACU70308"/>
        <property type="gene ID" value="Caci_1385"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1385"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="FGWAWVV"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="438"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1186" mass="125775" checksum="3EC0A21F1A8FDFE4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Y7</accession>
    <name>C7Q8Y7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_3401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3401"/>
    <dbReference type="EnsemblBacteria" id="ACU72307">
        <property type="protein sequence ID" value="ACU72307"/>
        <property type="gene ID" value="Caci_3401"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3401"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="AHECART"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU72307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="460" mass="46622" checksum="766E9018BF4A37FF" modified="2009-10-13" version="1">MDVGERYVLGRVIGEGATARVHEAEDTVLRREVAVKVFRDMDIGDSTSGRVDEETRILTRLAHPHLLPVYDSGRDADAHRFIVMPLVRGTTLAKLLAEGPIDPREVKRIGAALAGALAHIHARGIVHRDIKPSNVLLAEDGTPYLADFGFAHAVDGPALTATDCIVGTAGYLAPEQAEGFAVTPAVDIYALGLVLLEALTGEREYQGTPLERATANALRAPRIPARLGPGWLKVLRTMTAKTAAARPTADEVSTLVDAGEDTLPAPTAVGDTMELAETGSRGGLLAGASEPGSADWADWAHGSGAAAASVRAATADAAPARAADVTRRQPRRRLALLGAAACTAAAVVGLGADWLSSGASADTVGPSVTAPGAGAAGPQQSTVPSTGSTSPPSPAGPASSTDPGGSALPASAAHKPPSQSLSAPPPTTPPPTTPAQGPAPTKCPPGGGSKGNGHEKHKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9W0</accession>
    <name>C7Q9W0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7454</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7454"/>
    <dbReference type="EnsemblBacteria" id="ACU76279">
        <property type="protein sequence ID" value="ACU76279"/>
        <property type="gene ID" value="Caci_7454"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7454"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_11"/>
    <dbReference type="OMA" id="WINDHHR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="22"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="49264" checksum="A9B41521E8DC52DF" modified="2009-10-13" version="1">MDEIPDVLNVVGGQESAAVSGARLDLVDPSTGRVAGRSALSGAEDVDAACAAAASAFESWSVTTPAERQRALLRIADGVEARAEAFADAEVRETGKPRALFLRDEFPAIVDALRFFAGAARNMPGVAAAEYVEGRTSALRREPVGVCAQITPWNYPLMMAAWKLAPAVAAGNSTVLKPADTTPSSASLLARVAAEHLPPGVVNVVCGDRETGRALVAHPAVRLVAVTGSVRAGREIAAVCAGDLKRVHLELGGNAPVVIHDDVDVEATAAEVAAVAFYNAGQDCTAATRLLVHASIHDAFVDAFAKQVAALRTGPVADADFGPLNSAAQLSAVRGVLERLPAHADVVVGGRALDGAGWYHEPTVVVQVRQDDEIVQEETFGPVVTVQPFGTEAEAMALANGVRFGLAASVWTRDHDRAMRAVRGFQTGIAWVNTHGTTVSEMPHGGVKHSGYGSDLAMSGLLDYTQVKHVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA15</accession>
    <name>C7QA15_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="4" type="ordered locus">Caci_1490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785707.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1490"/>
    <dbReference type="EnsemblBacteria" id="ACU70413">
        <property type="protein sequence ID" value="ACU70413"/>
        <property type="gene ID" value="Caci_1490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1490"/>
    <dbReference type="eggNOG" id="COG2127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153743_1_0_11"/>
    <dbReference type="OMA" id="RDVQAMH"/>
    <dbReference type="OrthoDB" id="1829294at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="ClpS" evidence="3">
        <location>
            <begin position="22"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="11227" checksum="3739F3C202D5D8F1" modified="2009-10-13" version="1">MSVAPVEVDPEATEETRAAPVQDPMWVTVVWNDPVNLMSYVTYVFMTYFGYSKGKAERMMHEVHNLGKAIVSSGGREQMEKDVAAMHGYGLWATLQRQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA29</accession>
    <name>C7QA29_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ordered locus">Caci_1506</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785721.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1506"/>
    <dbReference type="MEROPS" id="C26.957"/>
    <dbReference type="EnsemblBacteria" id="ACU70427">
        <property type="protein sequence ID" value="ACU70427"/>
        <property type="gene ID" value="Caci_1506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1506"/>
    <dbReference type="eggNOG" id="COG0518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_11"/>
    <dbReference type="OMA" id="KRKIIGH"/>
    <dbReference type="OrthoDB" id="504464at2"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="199"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="226"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="523" mass="56347" checksum="160EF591CECBE00C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA83</accession>
    <name>C7QA83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1560"/>
    <dbReference type="EnsemblBacteria" id="ACU70481">
        <property type="protein sequence ID" value="ACU70481"/>
        <property type="gene ID" value="Caci_1560"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1560"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_14_2_11"/>
    <dbReference type="OMA" id="CSDQWPG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="64"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="22246" checksum="392C71D9566D9834" modified="2009-10-13" version="1">MSSPNGPPDGGPSIHPPSSPVPSDPVGSSGSGTGGPGTGGFGTGGPEPASEPGSQDRAEQPPPPRAGDRAPVFTLTDQHGQSVSLTDFRGKQAVLLVFYPFAFSRVCGSELQAIHESVEDFQNERVQVLAASCDALYSLRAYADEAGFGFPLLADHWPHGGAARAYGVFDAERGCAVRGTFLIDHEGVVRWTVVNGLADARSLDDYRAALAAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD6</accession>
    <name>C7QAD6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3529"/>
    <dbReference type="EnsemblBacteria" id="ACU72435">
        <property type="protein sequence ID" value="ACU72435"/>
        <property type="gene ID" value="Caci_3529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3529"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_11"/>
    <dbReference type="OMA" id="IVHECNR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="52630" checksum="521E0EE3EDE51F05" modified="2009-10-13" version="1">MPKSSVPGTASEGHSQEAVSAASSAPSAVASTAPGFRPLLGHSWQLVRDPLGWLDKCRQAGPVLRVKLGPRAAYLVTDPDLVHRVLTDPAFEKGGPLMDAARDLLGNGLATCWREDHRRQRPLMQPAFTLPRIAGYAEVMREEAAQLTATWTPHRETDLIDDLSSATLRVMIRAMLPTADAEAAGKVAQQVRILLDGALLRAAVPFPFLFRLPTPGNRRFDRARRDTFAAADRIVATARAKPDASGLLSALITSDGSAPDGSDAFTDEDLRDQVMTLLSAGGDTTATTLAWAFHLLATHPEAERRLHEELDTVLDGAIAGPDDLPRLPFTRNVVSETLRLYPPVWMMSRITIADVDLEGCRLPADTEVFFSSYQLHHDPRHFPDPEAFDPDRWDRREPGDRHSFIPFHSGSRKCMGNTFALTEAAIMLSAVASVWRFRPTPRHDARPRPPRSMTPADVHLVPEPRPGRLSETRGIHAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAH9</accession>
    <name>C7QAH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792207.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3573"/>
    <dbReference type="EnsemblBacteria" id="ACU72478">
        <property type="protein sequence ID" value="ACU72478"/>
        <property type="gene ID" value="Caci_3573"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3573"/>
    <dbReference type="eggNOG" id="ENOG5032RQW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118476_0_0_11"/>
    <dbReference type="OMA" id="TTILACW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980753" evidence="2">
        <location>
            <begin position="24"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="19515" checksum="10431DC2A2CCBBF9" modified="2009-10-13" version="1" precursor="true">MRALRLLAAVSVTAAMAAGCASAKATAPGASAPSTSSSPSAAAGATTAPTAGSSAAGPSASALMVCGTEIQGAVETILAASPAPTTTTTWTDHLYTCTYHLASGTLVLSVKESPDTASANTYLATLQRQLGSTTPLTGSEGLGNPGFQNAAGNVVVLKDDKTLHVDATGLAAASGPSKLSRADVAYEVTTDILGCWTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAK4</accession>
    <name>C7QAK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3598</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792232.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3598"/>
    <dbReference type="CAZy" id="GH63">
        <property type="family name" value="Glycoside Hydrolase Family 63"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72503">
        <property type="protein sequence ID" value="ACU72503"/>
        <property type="gene ID" value="Caci_3598"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3598"/>
    <dbReference type="eggNOG" id="COG3408">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030429_0_0_11"/>
    <dbReference type="OMA" id="KPPVHGW"/>
    <dbReference type="OrthoDB" id="70058at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005991">
        <property type="term" value="P:trehalose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="PTHR10412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="575" mass="63566" checksum="2B6223788D04E7F3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAU9</accession>
    <name>C7QAU9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794151.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5563"/>
    <dbReference type="EnsemblBacteria" id="ACU74422">
        <property type="protein sequence ID" value="ACU74422"/>
        <property type="gene ID" value="Caci_5563"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5563"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_2_0_11"/>
    <dbReference type="OMA" id="TRIAIHE"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="50"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="27574" checksum="B37654B56E7D55C0" modified="2009-10-13" version="1">METGPEDAEPGTLDPQSDPQSDPQSDPQSDPQSDPQSDPPQLGLRERKKQRTRIAIHEAAMTLFAERGYDHVTMAEIARAADVAPATVFTHYASKEDLVYELRHVANERLRVALRTRASEVGVLAAVKEWQQDMYEYYVQSPKQIDRSRTFSRLIRENPTLWSRSVGFMFERQNLLTELLVEQHPQADPFLLEVAAAQIAGAVQAAQVRYQGDLAAGMAKDEVLARATARSEQVYEQLARGLAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ3</accession>
    <name>C7QAZ3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="12" type="ordered locus">Caci_5607</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794195.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5607"/>
    <dbReference type="EnsemblBacteria" id="ACU74466">
        <property type="protein sequence ID" value="ACU74466"/>
        <property type="gene ID" value="Caci_5607"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5607"/>
    <dbReference type="eggNOG" id="COG0126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025427_0_2_11"/>
    <dbReference type="OMA" id="DMIFDIG"/>
    <dbReference type="OrthoDB" id="462069at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="351"/>
            <end position="354"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU74466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="41360" checksum="8B6EF18B9E5305D3" modified="2009-10-13" version="1">MKTLDDLDVAGKKVLLRSDLNVPLDGDRITDDGRIRASVPTINALLDKGARVIVAAHLGRPKGEPEAKYSLAPVAKRLGELLDASVTFASDTVGESAQAAVAAMPERSVVLLENVRFNAGETAKDDAARGAFADQLAALADVFVSDGFGAVHRKHASVYDIATRLPAGAGLLIQAEVTVLKKLTDDVARPYAVVLGGSKVSDKLAVIANLLEKADSILVGGGMLFTFLKAQGFEVGKSLLEEDQLDTVKGYLRRAAERGVEFVLPIDIVAATEFSASADHEVVSASAIPADRLGLDIGPESGKLFANKLSTAKTIFWNGPMGVFEMEPYAGGTRAVAQGLIDSDAFTVVGGGDSAAAVRQLGFDEASFGHISTGGGASLEYLEGKTLPGLAVLEEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBL9</accession>
    <name>C7QBL9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1675"/>
    <dbReference type="EnsemblBacteria" id="ACU70596">
        <property type="protein sequence ID" value="ACU70596"/>
        <property type="gene ID" value="Caci_1675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1675"/>
    <dbReference type="eggNOG" id="COG3336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054944_1_0_11"/>
    <dbReference type="OMA" id="CVFFWPL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019108">
        <property type="entry name" value="Caa3_assmbl_CtaG-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09678">
        <property type="entry name" value="Caa3_CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="34317" checksum="408D3D1E39C645C0" modified="2009-10-13" version="1">MSHLSPDLFLAGGDDVPPALTVTRILTAWTVDPWLAAVIVAVGGLYLYGVSTLTRRGDKWPIGRTVAFVGGGLGTMVVATMSSLGTYDDTLISVHMIQHMVLSMVTPVFLCLGAPVTLALRTLPVRWRKRLVRLLHSRFARVMSFPLVTGVLFVATPFALYFTGWYQATLEHPYLHEVTHLHFILVGSLWFWPLLGVDPVPNRLAYPFRLLAIFATLPFHAILGLTIMQDNDLLAASYYTSLGRTWGSSPLADQHAAGGILWGSGDLVGFFVFLALGIQWAQQSKREAEREDRRLDRLEAEEARRVSSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBX3</accession>
    <name>C7QBX3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792321.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3690"/>
    <dbReference type="EnsemblBacteria" id="ACU72592">
        <property type="protein sequence ID" value="ACU72592"/>
        <property type="gene ID" value="Caci_3690"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3690"/>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_1_0_11"/>
    <dbReference type="OMA" id="WRLWALD"/>
    <dbReference type="OrthoDB" id="735222at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022291">
        <property type="entry name" value="Bacteriocin_synth_cyclodeHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027624">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03882">
        <property type="entry name" value="cyclo_dehyd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03604">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="2">
        <location>
            <begin position="278"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="669" mass="72166" checksum="DCDD4EC700A17C30" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBZ7</accession>
    <name>C7QBZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucan endo-1,6-beta-glucosidase</fullName>
            <ecNumber evidence="7">3.2.1.75</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.75" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792345.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3714"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH30">
        <property type="family name" value="Glycoside Hydrolase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72616">
        <property type="protein sequence ID" value="ACU72616"/>
        <property type="gene ID" value="Caci_3714"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3714"/>
    <dbReference type="eggNOG" id="COG5520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014379_3_0_11"/>
    <dbReference type="OMA" id="WIDWNII"/>
    <dbReference type="OrthoDB" id="447059at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046557">
        <property type="term" value="F:glucan endo-1,6-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982720" evidence="5">
        <location>
            <begin position="28"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="6">
        <location>
            <begin position="508"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="666" mass="70350" checksum="12F045BF8E2499AE" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC97</accession>
    <name>C7QC97_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver and ANTAR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5687</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794274.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5687"/>
    <dbReference type="EnsemblBacteria" id="ACU74545">
        <property type="protein sequence ID" value="ACU74545"/>
        <property type="gene ID" value="Caci_5687"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5687"/>
    <dbReference type="eggNOG" id="COG3707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_65_0_11"/>
    <dbReference type="OMA" id="QKTSMDR"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005561">
        <property type="entry name" value="ANTAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008327">
        <property type="entry name" value="Sig_transdc_resp-reg_antiterm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03861">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036382">
        <property type="entry name" value="RR_antiterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50921">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="ANTAR" evidence="3">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="22849" checksum="D811234850E21B29" modified="2009-10-13" version="1">MTTESTPARRVIIAEDEALIRLDLKEMLQEEGYEVVAEASDGAAAVRLAEEYRPDLCIFDVKMPVLDGITAAEQVIEARIAPVLILTAFSQRELVERAAEAGVMNYLVKPFTKDKLVPAIEIAVSRHTQLTALEGEVADLGSRLETRKLVDRAKGILQTAHGMTEPEAFRWIQKTSMDRRMTMKEVAEVVISGSTAVGSPAAGASPAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA4</accession>
    <name>C7QCA4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794281.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5694"/>
    <dbReference type="EnsemblBacteria" id="ACU74552">
        <property type="protein sequence ID" value="ACU74552"/>
        <property type="gene ID" value="Caci_5694"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5694"/>
    <dbReference type="eggNOG" id="ENOG50341B4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1458814_0_0_11"/>
    <dbReference type="OrthoDB" id="2083506at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="19536" checksum="03838FF03028A770" modified="2009-10-13" version="1" precursor="true">MTTVVYAIIALLGVVVFLLFGAQIELFRTVEQIRDYAGLIDRPEPVSLGAAVGTAPSDYGLPAYLDSAHRAVVLFLSDKCATCRSIAAALDGALPRGVVVVIDAGPNGTPDLTLAFQLDPERTVVDAGRTIMDALGLNITPLGVVVQDGRLVRASTLPSTRQLYTLIEATNTSIGSRARELSQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCC5</accession>
    <name>C7QCC5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="10" type="ordered locus">Caci_5715</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794302.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5715"/>
    <dbReference type="EnsemblBacteria" id="ACU74573">
        <property type="protein sequence ID" value="ACU74573"/>
        <property type="gene ID" value="Caci_5715"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5715"/>
    <dbReference type="eggNOG" id="COG0139">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_5_1_11"/>
    <dbReference type="OMA" id="GRRTCFH"/>
    <dbReference type="OrthoDB" id="1842189at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="9">
        <location>
            <begin position="40"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="15810" checksum="14D44B334253F9F1" modified="2009-10-13" version="1">MTDEVATPALAPEIAARLKRDEHGLFAAIAQQHDTGEVLMLAWMDEEALRRTLVSGRVTYWSRSRAEYWTKGDTSGNVQILKSAAVDCDGDAVLLKVDQSGGACHTGDRTCFDAGDLPLGVDAETGASRDESRSAGSASAARGPLGESTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF1</accession>
    <name>C7QCF1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5741"/>
    <dbReference type="EnsemblBacteria" id="ACU74599">
        <property type="protein sequence ID" value="ACU74599"/>
        <property type="gene ID" value="Caci_5741"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5741"/>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_629612_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="46583" checksum="AF404BAC8C232630" modified="2009-10-13" version="1">MDRCAVLVDAGYVLAAAANVVSGDPGRPGIEVDYPGLVTALTERAAAETGLPVLRVYWYDAAPATGPTRDQRLLRVLDGLKLRLGKLVRRDDGKFEQKGVDTFLHADLTGLARKRAVADVVLVSGDEDLLHAVEEAQEYGTRIHLWGAASDYNQSLELIAAVDKSMTLSEEWLKPYVWVKVPIGHGEDPGCEPAKLGAHGEHAKPAHKAFPSPLDMPPRVLHPTESPKTPLANSRFPKLWQVTSPTQRFLDAEENKSFGRAEPIDVGRAYVARWMARATEAERRRLTDWTATWTWVPHDLDPDLLRFANDLGIDTWEAELEPIKHELRAGFLDGLKKWRDQHDTGGEPGAAAMVDSGTAPPPTAPPQHAPDVPASASAAESEGSAAPSETPPAASAAPTPPATPPTVPAPQSPPTEAGPPGSQHAPSPGAAGSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM1</accession>
    <name>C7QCM1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C60 sortase A and B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7660"/>
    <dbReference type="EnsemblBacteria" id="ACU76484">
        <property type="protein sequence ID" value="ACU76484"/>
        <property type="gene ID" value="Caci_7660"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7660"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083535_0_0_11"/>
    <dbReference type="OMA" id="WIPTHAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05830">
        <property type="entry name" value="Sortase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042003">
        <property type="entry name" value="Sortase_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="27464" checksum="DC250671BF5F14DA" modified="2009-10-13" version="1" precursor="true">MVSMSASLLAMFLLGWVVYAFGLSGLQEQHSQADLYRALAGELGQATAPVGPAADGTPLAILDIPAIGLHQAVVVEGTTGADLARGPGHLRYTVLPGQPGVSALMARRGMFGAPFASLPKLRVGDKITVTTGEGTFTYTVNAFGEGSKPVADSFPNRLVLATGDSTWIPTHAIYVGARLDGRPADGSGQRGTKTDLDKTMASDTDAWPALQLWALALALAVAATVALAAAWNRRAVYQSMAPVLAALLWCVYENATVLLPNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCM3</accession>
    <name>C7QCM3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_7662</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7662"/>
    <dbReference type="EnsemblBacteria" id="ACU76486">
        <property type="protein sequence ID" value="ACU76486"/>
        <property type="gene ID" value="Caci_7662"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7662"/>
    <dbReference type="eggNOG" id="COG0581">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033621_2_0_11"/>
    <dbReference type="OMA" id="WRTVWHV"/>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="153"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="366"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="43666" checksum="8F18D2263FE24F20" modified="2009-10-13" version="1" precursor="true">MTLIDIAAPAGGEAYLDDATGQVRVRPGALTAADAGTLAGAAAGALGLVWLVYERIMPWSGALGFWLCWYAAFIVFYWGIARTQWEARHVREKIAAALFTGAGILILVVLVDQVAYVAWRGEKAVGHGNFLTTDMQRTGPLDPLSSGGVLHAMIGSLEQLGLATLFAVPLGISAAVFMSEIGGRLAGPVRTVITAMTALPSIVAGLFILGSVILTLGYDRSGFAASLALTVMMMPIVTRASEVVIRIVPHTLREASYALGASQWRTVWNVVLPTARSGLTTAVLLGMARAVGETSPVLLTAGFTSAKNANPFSGQQVSLPLYVWSYVRYPQESMKIRAFGGALTLMAIVMILFIAARIVGGRRPGELTRRRRRQMARDRVRGAASPAAEPPRAVRPLPAAAAVVHPKPEPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCR0</accession>
    <name>C7QCR0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphomannomutase</fullName>
            <ecNumber evidence="5">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796248.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7699"/>
    <dbReference type="EnsemblBacteria" id="ACU76523">
        <property type="protein sequence ID" value="ACU76523"/>
        <property type="gene ID" value="Caci_7699"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7699"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065090_0_0_11"/>
    <dbReference type="OMA" id="GDWPQFQ"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PTHR10466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="27800" checksum="7DA06BB4C70D94B4" modified="2009-10-13" version="1">MTSHDPDARVLAFDLDGTLAESKTAITPRMAGLLVDLLDEVQVCIISGGAFPQFQTQVLDRLDATDEQLAKLNLMPTNGTRYYLHRDGGWREIYAEDLPEDTKRKVVGVLTEGAKTLGLWEDKTWGDIIEDRGSQITFSALGQQAPVAEKTAWDPDGAKKERLRAWAAERLPGLEVRSGGSTSIDVTAEGIDKAHGMRKLMAELHIGMDDILFVGDRLDPQGNDHPVEAMGIRSVAVKGWQDTADFVQGWLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD16</accession>
    <name>C7QD16_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall-binding domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786020.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1805"/>
    <dbReference type="EnsemblBacteria" id="ACU70726">
        <property type="protein sequence ID" value="ACU70726"/>
        <property type="gene ID" value="Caci_1805"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1805"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023724_0_0_11"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983037" evidence="1">
        <location>
            <begin position="36"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="688" mass="69137" checksum="FE770A75C6B80203" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD34</accession>
    <name>C7QD34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786038.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1823"/>
    <dbReference type="EnsemblBacteria" id="ACU70744">
        <property type="protein sequence ID" value="ACU70744"/>
        <property type="gene ID" value="Caci_1823"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1823"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049717_1_0_11"/>
    <dbReference type="OMA" id="IGHQWAY"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32457" checksum="4B9ED81229287D27" modified="2009-10-13" version="1">MTLHVIVGAGPVGTATAKLLADRGERVRVVTRSGSGPEHASIERVAADATDAERLSALTEGAAALYNCANPAYHQWLTDWPPLAAALLTAAERSGAVLTVANNLYGHGPVTGTITPETPLAATHPKLKLRADMFRDALALHQAGRIRMTEVRASDYVEANSIFSYVLAKPLDNGKRAYVPTPLNVKHSWTSIADVARTLALVSGDERAWGQAWLVPTSEPLTVRELADRYVAAKGLPPAKLTKLPYPVLWSAGLFDKMAKELRTTHYQFAKPFTLDSTLTEKTFGLAPTPIDEVLRTMTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDA0</accession>
    <name>C7QDA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792422.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3791"/>
    <dbReference type="EnsemblBacteria" id="ACU72693">
        <property type="protein sequence ID" value="ACU72693"/>
        <property type="gene ID" value="Caci_3791"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3791"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_2_11"/>
    <dbReference type="OMA" id="RGDRITM"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="29803" checksum="6E546DC064F26697" modified="2009-10-13" version="1">MNGHSIVAGTPPTIRRRRADQARQIADVLRQQVLNGAYHDRILPGENALIREFETTRNTVREALDLVRSEGLVDRVPGLGTRVAAEKYPHGLDMLLGLAETLGAHGPVTNEVRTAGLATAPPSIARHLGLPDRAPVVYIERLRSVSGLVLSLDLTYLAPEIGEPILAEDLERTDIFCLIERITGRRLGEAEISLEAVNADAHCADLLEVPRDSALLMLERLTRLDDGRPVDLEYIRFRGDRMRMSGRLVRPTVTVPDAGTDTDTDTDTDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEX7</accession>
    <name>C7QEX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5877"/>
    <dbReference type="EnsemblBacteria" id="ACU74735">
        <property type="protein sequence ID" value="ACU74735"/>
        <property type="gene ID" value="Caci_5877"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5877"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="VAHHISM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="188"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="42162" checksum="76762F22E9A22FB6" modified="2009-10-13" version="1">MGTAAAALAGAAVIEALARGAVHHRPGTSGVLLTAVFLALCATAPLGFLGVIGAATAVVAAAVLALTITGMLPVASAAAVVVAMYRLGWGAGSLAEPRARGRAQESGQIRMRRLAGILAAGLVVPFPVIALSVSRTSDAGVVAVVLTALAPAAAFAGNAAHARSEARVHQAAREAVARSLVEHTARGERARIARELHDVVAHHISMIAVQAETARLATPGMPPAGAERLLAIGDTARAGLTEMRRLLGVLREDAGPPDEQESRHPQPGLDQLLALVDAARRTSGATTRLIVSGAPAALDPGVELAAYRITQEALTNARRHAGGAPVDVELRFTAEALWLRVRDSGPGPGAGVGTGDGAVNQATDLPAGGHGVSGMRERATAVGGRLTAGPAPTGGFVVQAVLPAGSLESTNEIPDGDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFK3</accession>
    <name>C7QFK3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796505.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7957"/>
    <dbReference type="EnsemblBacteria" id="ACU76780">
        <property type="protein sequence ID" value="ACU76780"/>
        <property type="gene ID" value="Caci_7957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7957"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_11"/>
    <dbReference type="OMA" id="VHRFMAD"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="10"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1324" mass="145286" checksum="D912BF2DACC26F72" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ3</accession>
    <name>C7QFQ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.129" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784287.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0037"/>
    <dbReference type="EnsemblBacteria" id="ACU68992">
        <property type="protein sequence ID" value="ACU68992"/>
        <property type="gene ID" value="Caci_0037"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0037"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_1_0_11"/>
    <dbReference type="OMA" id="VPYGWFV"/>
    <dbReference type="OrthoDB" id="423699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980935" evidence="1">
        <location>
            <begin position="32"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="490" mass="51015" checksum="BAE9403113BC4F7F" modified="2009-10-13" version="1" precursor="true">MNQPIRRVAIFCFLLIASLLVSSNYLQVVNADSYKARAGNQRTELDYYAYPRGKILTADGTVIADSVPSGGLQYKYQRTYPLKADYANITGWKSIVYGSRDIENVLDKYLQGTDSSESVANFMDTLTGKSKKGGDVQLTLQNAVQQAAIKGLGKQNGSVVALDPTTGAILAMYSSPSFDPNGIASNVSETSTAAGNALEADKGKPNLNHAIGENYPPGSVFKIVTAAAALDSGKFTETGSTGADPNFYSNGSGYKLKNEDGTCSGTDLKTALAESCNSVYGFVGATLGSQIMSTYASKFGFNDPSLKIPLQVAQSNFPSPATVGTNVLGLAQDSIGQGDTQVTPLQAAMIAAAVANGGTIMQPYMVDKETAPNGHVTYKGSDHQHELSQAMSPATAATLDDMMQNVVTHGTAQGRGIPGVQMGAKTGTAQRASGQNPLAWFVCYGTANGKKVAVAVMVDTNDPSIRSDVSGVNFAGPTAQAVLKAALGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFS4</accession>
    <name>C7QFS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1981"/>
    <dbReference type="EnsemblBacteria" id="ACU70901">
        <property type="protein sequence ID" value="ACU70901"/>
        <property type="gene ID" value="Caci_1981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1981"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="758"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1033" mass="112396" checksum="C30F8C78E6093846" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG34</accession>
    <name>C7QG34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786304.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71011">
        <property type="protein sequence ID" value="ACU71011"/>
        <property type="gene ID" value="Caci_2092"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2092"/>
    <dbReference type="HOGENOM" id="CLU_2354611_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983191" evidence="1">
        <location>
            <begin position="30"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="9970" checksum="A72BED59FD2B6113" modified="2009-10-13" version="1" precursor="true">MIARRAVRLAAVTALAASSIGVGVATASAATHVRPASTFLCSADGNGNSLFAAEHDAEETLKGDYTVLSGFTLQYSTEHPDGSWYVVMTAHCGNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG38</accession>
    <name>C7QG38_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786308.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2096"/>
    <dbReference type="EnsemblBacteria" id="ACU71015">
        <property type="protein sequence ID" value="ACU71015"/>
        <property type="gene ID" value="Caci_2096"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2096"/>
    <dbReference type="eggNOG" id="COG1252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_7_1_11"/>
    <dbReference type="OMA" id="RGIFQYR"/>
    <dbReference type="OrthoDB" id="403436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="452" mass="48892" checksum="9EB9DC4ECF75F225" modified="2009-10-13" version="1">MRTILVVGGGYAGFYTAWKLEKKLRRDEARIIVVDPRPYMTYQPFLPEVLAGSVEARHAAVSLRRHLRRSTIVAGSVVAIDHARRTVTVRPAEGPEFAIEYDIVAVTAGAVTRKLAVPGVAEQAIGLKHVEEAVAIRDRLLTAFDRASALPPGPRRQALLTATFVGGGFSGVEGFAELLSLASALVRSYPELDPAELNFHLVEAGKRILPEVSEEPGKWVVRSLEKRGARVHLGATLVSALDGHVVLSTGEEFDSELIVWTVGNAANPMVRSHTDLPIDRRGMLVVRSDLRVGTEDAPIPDAWGAGDDAAVPDLAAGRPGATTVPNAQHAVRQGKLLAKNIAAALRGREPKPYVHHSLGTVATLGLGRGIFQYRGLVIKGFPAWLMHRGYHVLAVPSWERKVRVFAIWLTAAVFGRDIVSLASVQDPRRAFVTGGEPLEARAEPPGYRARSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG69</accession>
    <name>C7QG69_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72914">
        <property type="protein sequence ID" value="ACU72914"/>
        <property type="gene ID" value="Caci_4048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4048"/>
    <dbReference type="HOGENOM" id="CLU_2258664_0_0_11"/>
    <dbReference type="OrthoDB" id="1302813at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="11207" checksum="91E3FCA04DA60F7F" modified="2009-10-13" version="1">MIGYVTVLRATARFYPEGLTGPLPNPYPEMMIGDPKAGTVFRCVLHLDDAEAIEPGACGPARVDLLWNLVPDWPEPWLLWHGRIIGELTGLAPEDPPSAASQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI79</accession>
    <name>C7QI79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792853.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4260"/>
    <dbReference type="EnsemblBacteria" id="ACU73124">
        <property type="protein sequence ID" value="ACU73124"/>
        <property type="gene ID" value="Caci_4260"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4260"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070328_0_0_11"/>
    <dbReference type="OMA" id="GHSYAAN"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="36525" checksum="086C3F9DB8D8BA58" modified="2009-10-13" version="1" precursor="true">MSISESPHRTKIFLGAVAVLLAIAVGAAVVAYQGRPTARAGVKGAVVLDQSDSLDTGSGYLLYKTTVAGPDFGTLAERKLSADSSGVVGVPTLSNIQCDRSYTASGILLCLRADENLVRVASVEVYDTSLKLIKKVQAAGIPNRARLSADGRMAAWTTFVAGDAYVGPAFSTRTSILDLKTGALTASLESFAVTLQGKPYHAVDENVWGVTFADDNTFYATLGTAGRTWLVRGDVAAHTLTTLTDNVECPSLSPDGTRVVFKKRVSSDAWKMWHLEVLNLATMTETPLAEQRSVDDQAAWLDDHTVMYAVPQSGSSGYDVWSTPADGSGKPVLVAPNAFSPSVTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ7</accession>
    <name>C7QIJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-phosphogluconate dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794803.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6220"/>
    <dbReference type="EnsemblBacteria" id="ACU75074">
        <property type="protein sequence ID" value="ACU75074"/>
        <property type="gene ID" value="Caci_6220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6220"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_780395_0_0_11"/>
    <dbReference type="OMA" id="RWRIANK"/>
    <dbReference type="OrthoDB" id="988771at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039437">
        <property type="entry name" value="Put_lumazine-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12893">
        <property type="entry name" value="Lumazine_bd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="39899" checksum="8D13EB8A08C616E0" modified="2009-10-13" version="1">MKTPQTIAVLGLGHLGSAIANRLGDQGQSVVGWTRSGGTDANEAVEKADVVLLCLFDGTACREVLDHVRDSLKADAIVLNTSTIAPGEAAEFARRFGPRYVHVPVLGSVRAVAAGALKLLAAGDAESFDRVQPILEALGTVLRIEDAAKAAALKLVANSSLAGAALAVRDALQQAEALGLSRDEALDVLELGQLGGLVARKRDFLTQPPTASSVAEAEFTIGALAKDMALLADASSKPVSSAAELADAADAAGVPEADIAVAMTTPAVDDAVLEPLRAYIRGHATGDPAHFREAFLASAHVEGIRGGAFVSWPLEEYCALFRGQPAADEASRTRRIDSVRVHGNVASASMTLHHGADTFTDIFLLVDGEGGWRIANKAYYRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIR8</accession>
    <name>C7QIR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, CarD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8145"/>
    <dbReference type="EnsemblBacteria" id="ACU76968">
        <property type="protein sequence ID" value="ACU76968"/>
        <property type="gene ID" value="Caci_8145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8145"/>
    <dbReference type="eggNOG" id="COG1329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048259_1_2_11"/>
    <dbReference type="OMA" id="DMKVMIP"/>
    <dbReference type="OrthoDB" id="1942592at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042215">
        <property type="entry name" value="CarD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CarD_TRCF" evidence="1">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17946" checksum="094DDBE54DA18CAB" modified="2009-10-13" version="1">MTFKVGETVVYPHHGAALIEDIEIRVIKGEPKEYLVLKVAQGDLTVRVPSEKAEYVGVRDVVDQGGLERVFDVLRAPHTEEPTNWSRRYKANIEKIQSGDVIKVAEVVRDLWRRDRDRGLSAGEKRMLAKARQILVSELALAEATNEDKADAILDEVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV6</accession>
    <name>C7QIV6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796731.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8183"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77006">
        <property type="protein sequence ID" value="ACU77006"/>
        <property type="gene ID" value="Caci_8183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8183"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023845_9_1_11"/>
    <dbReference type="OMA" id="HVCAIPL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="32629" checksum="3F5D6209CE271DC7" modified="2009-10-13" version="1">MPTIAAVATAFHPDERLTAVVEAALKSCARVVVVDNTPGDGPFLADTLRDREGVTVLRDGKNRGLAGALNTGVDTLLAGQSAQPDLLLFLDQDSVLGEDLVLALAQHLTDPAVGIAAPAAWDEDQQRYYEPGTEKGPDVADRDTVITSGMLVRREVLAEVGRFRTEFFVDHVDNDFCLRVRAAGYRVLRDKRQKLAHSLGQRNQHKLPGVSVSSSRHPTWRLYWIARNGTVLMREHRKDAPAWTRTTAAYLVWWFALRTAIEAPRGPRAMAMLRGFRDGARGRTSRRYLPPGAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ4</accession>
    <name>C7QIZ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796769.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8221"/>
    <dbReference type="EnsemblBacteria" id="ACU77044">
        <property type="protein sequence ID" value="ACU77044"/>
        <property type="gene ID" value="Caci_8221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8221"/>
    <dbReference type="eggNOG" id="ENOG502ZFM2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2011153_0_0_11"/>
    <dbReference type="OrthoDB" id="2207360at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="12968" checksum="98A9BCEF980537D0" modified="2009-10-13" version="1">MSIEVQLGISFRVDGPESAEELAQSAGKVMEALLALEECNSELSDAGVAMDADQMIVEVELKASGASEPESIERALAAVRTAIHAAGHGTPDWQTSSRYATPDISVEGATGTFRRLQFTASVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ15</accession>
    <name>C7QJ15_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septum formation initiator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0202"/>
    <dbReference type="EnsemblBacteria" id="ACU69157">
        <property type="protein sequence ID" value="ACU69157"/>
        <property type="gene ID" value="Caci_0202"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0202"/>
    <dbReference type="eggNOG" id="COG2919">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085342_0_3_11"/>
    <dbReference type="OMA" id="RRVFSCD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="21497" checksum="AC11304B71685D8B" modified="2009-10-13" version="1">MKSAGSGSTPGRLSAVPTQRQDAASGTSRSSGDGGSGSGASAKRRTRYTARAAILMLVVCALVLALAYPLQQYFSQSSQINQLKQQNAHKRTQVQQLGRQLTQWQDPDYVKIQARLRLHYVFPGETGLRLLGAGDAATGGPDGTTGPSQGSSAWYAQLWNSVTAASGAPTSSGAPTTPATSGASGSAGASGPSGTPTPSGGPARSATSPAPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJV2</accession>
    <name>C7QJV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4326</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4326"/>
    <dbReference type="EnsemblBacteria" id="ACU73190">
        <property type="protein sequence ID" value="ACU73190"/>
        <property type="gene ID" value="Caci_4326"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4326"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_17_0_11"/>
    <dbReference type="OMA" id="CTPGDTH"/>
    <dbReference type="OrthoDB" id="1339160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="2">
        <location>
            <begin position="26"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="3">
        <location>
            <begin position="167"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="43857" checksum="25532582504A47CC" modified="2009-10-13" version="1">MSGDGSGLVSGDGESNNGNSGGSSTLRIGLIGHGFMGRMHSLAWQSVGRAVEVPLVPELIAIAGRNPGSVAKAARAWGWQSWTDDWRTLVARDDIDVIDITTPGALHAEIALAALAAGKHVLCEKPLANTLAEAREMTAAAEEAAARGVLSMVGFNYRRTPALALARDLVAQGRLGEIRHVRAVYLQDWINDPEFPLVWRLRKEEAGSGALGDLGAHLVDLAYFLTGRRITGLSARTRTFVEERPLATSASGLSGAAGSERGRVTVDDAAVFFADCEGGALATFEATRFAPGRKNAMRIEVNGSEGSVAFDFEAMNELQFYDATSDAAGAGFSRILATEPQHPYLDAWWPPGHGLGYDHTFVNQKRDLIEAIAAGKAPTPSFADGLYVQGVLAAVEDSARNRSAWTAVTQEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK75</accession>
    <name>C7QK75_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transketolase central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794878.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6295"/>
    <dbReference type="EnsemblBacteria" id="ACU75149">
        <property type="protein sequence ID" value="ACU75149"/>
        <property type="gene ID" value="Caci_6295"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6295"/>
    <dbReference type="eggNOG" id="COG3958">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_1_1_11"/>
    <dbReference type="OMA" id="VINTCDY"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="2">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35264" checksum="FD58024ECE924098" modified="2009-10-13" version="1">MNRATREAYRDTLIPLLSRHPELMCLDSDTGLFGADHVAEAGEQYLNLGIAEQNLMGVAAGMAACGRVPFVNTMAAFAASRALESIKIDIAYNRLPVRIMATHGGLAAGHLGPTHQALEDLAVLRVLPGMTVVVPADAAATEAFVEQSVTLPGPLYVRLGRKPTPPLPEGPPPVIGQAQWLRHGEDVVLVACGPYPVLACLDAADELAGHGIEASVLNMHTLRPLDTGTLIAAARPARLVVTLEEHWRSGGLGGAVAEALAESEPVRVLRLGVPDTFVSEVGNQEHLVRHYDLTAERVVGAVRAALDTSARSDRPARPDRPAIPDYDKELVS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE2</accession>
    <name>MSHB3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 3</fullName>
            <shortName evidence="1">GlcNAc-Ins deacetylase 3</shortName>
            <ecNumber evidence="1">3.5.1.103</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshB3</name>
        <name type="ordered locus">Caci_6362</name>
    </gene>
    <organism>
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate</text>
            <dbReference type="Rhea" id="RHEA:26180"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:52442"/>
            <dbReference type="ChEBI" id="CHEBI:58886"/>
            <dbReference type="EC" id="3.5.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MshB deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.103" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7QKE2"/>
    <dbReference type="SMR" id="C7QKE2"/>
    <dbReference type="STRING" id="479433.Caci_6362"/>
    <dbReference type="EnsemblBacteria" id="ACU75216">
        <property type="protein sequence ID" value="ACU75216"/>
        <property type="gene ID" value="Caci_6362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6362"/>
    <dbReference type="eggNOG" id="COG2120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049311_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035595">
        <property type="term" value="F:N-acetylglucosaminylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01696">
        <property type="entry name" value="MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017810">
        <property type="entry name" value="Mycothiol_biosynthesis_MshB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03445">
        <property type="entry name" value="mycothiol_MshB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000400175" description="1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 3">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01696"/>
        </source>
    </evidence>
    <sequence length="355" mass="37760" checksum="C2A40C624B33A25C" modified="2009-10-13" version="1">MTLPLDLLDMPFARLGDRLGNPLRLLMVHAHPDDETTTTGATAALYAAETIDVYLVTCTRGERGEILDPEAQRVVDDAADGEQALGELRVRELAGAVTMLGIKGSRFLGGAGRWWDSGMAGEESNTDPRSLVAGDFQEQVDALAAAIREIRPQVLVTYDSRGGYGHPDHIRAHQLSLAAVDRAAETGGESESGGEGGGEGAEAWSVAKVYAAVVPFSILRSVARRLGSNGDSPFAPLAEALANGVPEDLIEIPYGVPDHLVTAQIDARDWLDAKTAAMRSHRSQMAADSWFFKLAASSDGGFGIEHFQLLRGTAGPLDDGFEADLFAGVRAVDDSDCEPDFGWLPEEEPAGGELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKH0</accession>
    <name>C7QKH0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydrogen cyanide + thiosulfate = 2 H(+) + sulfite + thiocyanate</text>
            <dbReference type="Rhea" id="RHEA:16881"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:18022"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="EC" id="2.8.1.1"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796794.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8246"/>
    <dbReference type="EnsemblBacteria" id="ACU77069">
        <property type="protein sequence ID" value="ACU77069"/>
        <property type="gene ID" value="Caci_8246"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8246"/>
    <dbReference type="eggNOG" id="COG2897">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_1_3_11"/>
    <dbReference type="OMA" id="QRPGHVP"/>
    <dbReference type="OrthoDB" id="1385159at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="154"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="32071" checksum="508B7AE3A9BF52D9" modified="2009-10-13" version="1">MSRNDVLVDADWVQAHLDDPKVVLVEVDEDTAAYDKNHIRNAVRIDWKRDLQDPVRRDFVNQEQFQALLSERGIANDDTVVLYGGNNNWFASYAYWYFKLYGHGDVKLLDGGRKKWELDSRELVVEQPTRAATSYTAQPQDQSIRAYRDDVVAAIGSTNLVDVRSPDEYSGKLLAPAHLPQEQSQRPGHVPTAANIPWSKAANDDGTFKSDDELTALYEGEGVDLSKDTIAYCRIGERSAHTWFVLHELLGQDNVKNYDGSWTEYGSLVGVPVSLGSNPGSPEGGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK4</accession>
    <name>C7QKK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796828.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8280"/>
    <dbReference type="EnsemblBacteria" id="ACU77103">
        <property type="protein sequence ID" value="ACU77103"/>
        <property type="gene ID" value="Caci_8280"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8280"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_6_4_11"/>
    <dbReference type="OMA" id="QMLAVWQ"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019952">
        <property type="entry name" value="F420_OxRdatse_Rv1855c_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03560">
        <property type="entry name" value="F420_Rv1855c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30774" checksum="3BC8FB9B7EABBA91" modified="2009-10-13" version="1">MANLRFGIKLSQDATIDEYKAVWRIADEARFDHCWNMDHFASLGGDDTKDIFEAWTALAGMAALTSHVRIGCSVTGNTYRHPAELAKMAVTVDHLSGGRLEFGIGAAWAENEHTMLGLPFGTAGDRADRLEEALKIITSLWTESRTTHDGKHYQLKDAIAEPKPLQTPHPPIWIGGSGRKRTLRMAAEYAAVWNAAGGTPPEVAEASAVLDQHCADVGRDPATIRRSVQIRVGDDFDALKRTLEEFAAIGITDPLLIVQTDNPVARAERLATELPRLREIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK7</accession>
    <name>C7QKK7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796831.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8283"/>
    <dbReference type="EnsemblBacteria" id="ACU77106">
        <property type="protein sequence ID" value="ACU77106"/>
        <property type="gene ID" value="Caci_8283"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8283"/>
    <dbReference type="eggNOG" id="COG0500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071058_1_1_11"/>
    <dbReference type="OMA" id="PLEVERW"/>
    <dbReference type="OrthoDB" id="1865374at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22582" checksum="EACF94305D64FEC5" modified="2009-10-13" version="1">MSDAGAWTASAPYARAINDPTEQLVLHADSGETLLLDAAKFSAPPDAVDKAVLDRCLGPTLDLGCGPGRLVAELAGRGVPALGVDVAPFALLLSRANGATALRRSIFDRLPGAGRWPHALLMDGNIGIGGDPGALLERLCTLMRPRSGELIVETETEDVDVRYRVRFGYAGDEFGWARIGSEALLALAIPLGYVARQVWTADGRRFVALNYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL9</accession>
    <name>C7QKL9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8295"/>
    <dbReference type="EnsemblBacteria" id="ACU77118">
        <property type="protein sequence ID" value="ACU77118"/>
        <property type="gene ID" value="Caci_8295"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8295"/>
    <dbReference type="eggNOG" id="ENOG5033DYY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1008053_0_0_11"/>
    <dbReference type="OMA" id="EYGGFTY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="31026" checksum="2727E1E153981382" modified="2009-10-13" version="1">MVIDGGSGGPGRTGDGAPRRGRPGRAPRIEQPQTIIRLPKDPYEGEFKAPRARRGRGVLALAAIVIVVAAVIAINSSKHNTGAASQGASTGVGGGVPPATATVGQSAPAGGSSSPAFPAQSGANGVLTGYKDTQSGAEAAATNYVAAYVSEPMVHTNQRHTMIQTIADPSIVAHLQSELDTAFTEAARGYGLDANGNPPAGQTLVYRGVPAGVRVNSYTDTKAVVDVWTCTIDGIAGTGSTFPVSATWSTLTITLTWVGNDWRWNDFGQIDGPTPVGGTQQASTSDELQKAAKQFARLQYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM3</accession>
    <name>C7QKM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginase/agmatinase/formiminoglutamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796847.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8299"/>
    <dbReference type="EnsemblBacteria" id="ACU77122">
        <property type="protein sequence ID" value="ACU77122"/>
        <property type="gene ID" value="Caci_8299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8299"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_2_11"/>
    <dbReference type="OMA" id="VMPAVDS"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="32231" checksum="7768A0C0C6CD0979" modified="2009-10-13" version="1">MIALLAAPTNLGLRPPHPSSVPGTAKAPEAFRETGLFARFTDAGARDAGVVLPGRYADDATPGRLRNQDAIVEHARRLARRVAEIRAAGDVPLVFGGDCSLVVGVGLALRPAGRFALVHLDGHTDFRNPGNSDACAALAGEDLAAAIGRHWPAIADVDGLGPYFDPADTVHAGCRDDDQELAEVEEAISLTIPASAIIRDGAAATADRVRERVERADLDGYWLHLDVDILDATVMPAVDSPDPGGLLPDQLTELLAALAPGAAGAHVAVFDPDLDPDGRHARLLTDIVTDGLGQLGTELKPAAAHNAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM4</accession>
    <name>C7QKM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796848.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8300"/>
    <dbReference type="EnsemblBacteria" id="ACU77123">
        <property type="protein sequence ID" value="ACU77123"/>
        <property type="gene ID" value="Caci_8300"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8300"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_1_0_11"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="191"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="37380" checksum="9DA46E884F83F4F5" modified="2009-10-13" version="1">MEFTRFDHDQASDAEFDEVARFLASMDAADRPGWSSRSATALADFLKNRQSFGYDVSLWLGSEASGGAERLTASCWLNLALSPENRQTVLVEIRVRPDLRRRGIASDFLRALTPMIRVAERDHVIGSTTSHGPGELWGASVGMKPTLRYVRQVLRLGDADQSLWDRPVPDGYRFEDWTDRTPDRLVASYAVALQAMDDAVSGDLQWSQPRWTPERVRETEERLAATGNAARVVAAVDEASGEVAGLTQIAVSATRPEVVEQLDTSVRREHRGRGLGLAMKAAQLRAIAERPGLERVKTDTADLVHMAAINRALGFQDESEDVYIEADLAEIEAALATDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM6</accession>
    <name>C7QKM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8302"/>
    <dbReference type="EnsemblBacteria" id="ACU77125">
        <property type="protein sequence ID" value="ACU77125"/>
        <property type="gene ID" value="Caci_8302"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8302"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="DAAKPHG"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35836" checksum="A15736BBD5B9B28E" modified="2009-10-13" version="1">MKYRILGSDGPRVSALGLGCMGMSDFYSVTPESEAESISVLHRAIDDLGVTLLDTADMYGKGANEQLVGRALRGGRRDKVVLATKFGIRRDPETDERSIRNDPEYVRTAVDASLSRLGVDHIDLYYMHRRNPDVPVEESVGAMAELVQAGKVRYLGLSEVNAETLRAAHAVHPITALQSEYSLFTRDIEAQVVPAARELGVGIVPYSPVGRGLLTGAITSVEGLAADDFRRGNPRFADGNLEANLKLVAELRAVADESGHSPVQLALAWLLAQGPDIVPIPGTKRIKYLEENSAAADIELSAEQLARIEAAVPHGAASGERYAPDSARRTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR7</accession>
    <name>C7QKR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8343"/>
    <dbReference type="EnsemblBacteria" id="ACU77166">
        <property type="protein sequence ID" value="ACU77166"/>
        <property type="gene ID" value="Caci_8343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8343"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045657_0_0_11"/>
    <dbReference type="OMA" id="RPGMNAV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981083" evidence="2">
        <location>
            <begin position="26"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="58"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="462" mass="45403" checksum="563E62B928E7C26F" modified="2009-10-13" version="1" precursor="true">MTKRGTALAGLVLSSLLTAGLTACGSGGPSGVTKAPVAYGAVTQVVEAPATVTPKTQITVNATAGGSVAQLMVADGQHVTAGQTLLRIDSPDAQAQLNAAKAADAQAAAQGKRSSSGSSAIDFSESESLADANAQKSFDAAQTTAEQIADPAIKASILKQITSARNQYATASSDVRSTIANFNNGLASASDVVGSLSGAQRTQTQAAVAIAQKTVDSLTMKASIAGDISLRSGVGGASASGVDVSSLLSQLGGNLGSLAGAAGGSLGSAASGGGSTDPSDDTVITQGSPVDSGAALLVITDSSTLTLTAQVDETSILQITPGITADVQLDAVPDADYQASVISIDSQGQSSSRGGVTYRVRLSLGAGKLGDGSAAPVPRPGMSAVADLQVANKAHVLAVPSAAVVHVGNQDTVWLVASGTAHRHVVRLGAQGDTTVEVSSGLNPGDVIVTSGADKVHDGQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD8</accession>
    <name>C7PVD8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alanine racemase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784589.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0341"/>
    <dbReference type="EnsemblBacteria" id="ACU69294">
        <property type="protein sequence ID" value="ACU69294"/>
        <property type="gene ID" value="Caci_0341"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0341"/>
    <dbReference type="eggNOG" id="COG0787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_811013_0_0_11"/>
    <dbReference type="OMA" id="FAEPPHM"/>
    <dbReference type="OrthoDB" id="859043at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="38334" checksum="47CAA8DAF69CB11A" modified="2009-10-13" version="1">MSLTLHIDAERWRAHQDEVLARHPDLVPVAKGVNGYGIGIPNLMQAASKLAAAGVEITAVGTAAEAEQAKDHYSGRLLVLTPYLIGEDVRDLPDRVIRTVASVEAVEALLGRRVVIDLMTSMRRFGLEKQDIPRLHAALESDQARVEGFSVHMPLDRVAGDYLREVSDWVDALVAAGIPVRTLFVSHLSPDEISTLAKRHQGTTVRPRIGTQLWLGDRKALQARGTVHSVQKVSKGDRFGYRQHKARGDGHLLVVSGGTAHGVGLENPKNFGRGPAGLTPRAKFAARAAMALLNRTMSPYSWQGKTLWFAEPPHMQVSVLFLPAGVAPPKVGEEIPVEVSPVMTHVDRVVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVE8</accession>
    <name>C7PVE8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784599.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69304">
        <property type="protein sequence ID" value="ACU69304"/>
        <property type="gene ID" value="Caci_0351"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0351"/>
    <dbReference type="HOGENOM" id="CLU_2680928_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982222" evidence="1">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="7157" checksum="780C6453B39D14F3" modified="2009-10-13" version="1" precursor="true">MRKFATFAALALSAGTAVAGGACVANADVNLGVDAPTTSTAPAAGSMDFAGTWCGAPWLWSGQQAGAGCNAQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ5</accession>
    <name>C7PVJ5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Neprosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0399</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784646.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0399"/>
    <dbReference type="EnsemblBacteria" id="ACU69351">
        <property type="protein sequence ID" value="ACU69351"/>
        <property type="gene ID" value="Caci_0399"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0399"/>
    <dbReference type="HOGENOM" id="CLU_996345_0_0_11"/>
    <dbReference type="OrthoDB" id="1169185at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004314">
        <property type="entry name" value="Neprosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03080">
        <property type="entry name" value="Neprosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980390" description="Neprosin domain-containing protein" evidence="1">
        <location>
            <begin position="41"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Neprosin" evidence="2">
        <location>
            <begin position="80"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="27508" checksum="192D0A74FF2BF048" modified="2009-10-13" version="1" precursor="true">MPAQALRALLGNLRTRIAAAAVSAAALGAVVVLPASSAHAAQCWYGSCFSYVTGRQYTNTTGASVTMEQAAPRNVAADGHSLQELSLQTSGGTTVADTIEIGWTVDPELNGDYQPHLFVFHWVDGQPTCYNACGFVQVSTTVRAGMAVTPGTTGVFALRYYQGNWWAYYNNVAFGYFPGSAWKGAFTSAQIVSAFGEVASDSAPSCTQMGDGIYGSQSGASSISGYQLYGSTDRPALTVTATDPGSYNYGAVTGTSFNLGGPGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW36</accession>
    <name>C7PW36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-galactosidase</fullName>
            <ecNumber evidence="6">3.2.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793013.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4420"/>
    <dbReference type="CAZy" id="GH35">
        <property type="family name" value="Glycoside Hydrolase Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73284">
        <property type="protein sequence ID" value="ACU73284"/>
        <property type="gene ID" value="Caci_4420"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4420"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007853_7_2_11"/>
    <dbReference type="OMA" id="RAHPDTW"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
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        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="5">
        <location>
            <begin position="11"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="584" mass="63094" checksum="B1387C44BFB8675F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA5</accession>
    <name>C7PWA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4490"/>
    <dbReference type="EnsemblBacteria" id="ACU73353">
        <property type="protein sequence ID" value="ACU73353"/>
        <property type="gene ID" value="Caci_4490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4490"/>
    <dbReference type="eggNOG" id="COG1830">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056329_0_0_11"/>
    <dbReference type="OMA" id="FELDDRM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="42730" checksum="6144881956B74F94" modified="2009-10-13" version="1">MVAAISWLASGSELAAAISWLVLGSEVGGATSWRVPSSEVAVAISWRDPGSEVAAAMLLCASSIWLAATRMPHKLSVLVVSCMSPSPKLCLGLDALLCRVLQRSWRWFMVEVGEIRRLRRVRVAEPEAIAAAASARRRRGALVDGGGRLMLIAADHPARGALGVRDDPLAMGDRRELLERLVVALGRPGVDGVLATPDIVEDLLLLGALEDRVVVGSMNRGGLAGSVSELDDRFTAYDAAAIASSGLDGGKMLLRIDLRDPDTVSTLEACGRAVSELAARRLVAMIEPFMATRAGDGRLRNDLSVAAVVRACAIAAGLGSTSAYTWLKLPVVEEMERVLAATTLPVLLLGGDPDVAPEETYAAWEKALALEGVHGLVVGRALLYPPDGDVAAAVDTAAALVKPGVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA6</accession>
    <name>C7PWA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate protein central region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793083.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4491"/>
    <dbReference type="EnsemblBacteria" id="ACU73354">
        <property type="protein sequence ID" value="ACU73354"/>
        <property type="gene ID" value="Caci_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4491"/>
    <dbReference type="eggNOG" id="COG3962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_6_0_11"/>
    <dbReference type="OMA" id="PNTYHLE"/>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016823">
        <property type="term" value="F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019310">
        <property type="term" value="P:inositol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030817">
        <property type="entry name" value="Myo_inos_IolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF9">
        <property type="entry name" value="PTHR18968:SF9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04377">
        <property type="entry name" value="myo_inos_iolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="19"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="235"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="432"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="637" mass="67373" checksum="E658E6EDABAC6F33" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWJ7</accession>
    <name>C7PWJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75277">
        <property type="protein sequence ID" value="ACU75277"/>
        <property type="gene ID" value="Caci_6423"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6423"/>
    <dbReference type="HOGENOM" id="CLU_1709939_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16627" checksum="199DC715F30D0930" modified="2009-10-13" version="1">MALNALRSDLVGYAQEADPEIEGSVLHEAAYLMTAGDAWLRVITDDNPPDWESPVLLVAELFASVIGGEKPLLFANLICLWRGERPVWCLVQFGESAIRPTGVSSRQLYGVEVDVQRPESDAGFLSPAVPSDVIELFTQALTSLGIEGQQADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWS5</accession>
    <name>C7PWS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796907.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8359"/>
    <dbReference type="EnsemblBacteria" id="ACU77182">
        <property type="protein sequence ID" value="ACU77182"/>
        <property type="gene ID" value="Caci_8359"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8359"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_298728_0_0_11"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd14948">
        <property type="entry name" value="BACON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024361">
        <property type="entry name" value="BACON"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19190">
        <property type="entry name" value="BACON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BACON" evidence="2">
        <location>
            <begin position="817"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1005" mass="103005" checksum="A75AAB19AB78E248" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX45</accession>
    <name>C7PX45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0444"/>
    <dbReference type="EnsemblBacteria" id="ACU69396">
        <property type="protein sequence ID" value="ACU69396"/>
        <property type="gene ID" value="Caci_0444"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0444"/>
    <dbReference type="eggNOG" id="COG4412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465175_0_0_11"/>
    <dbReference type="OMA" id="THAGSWE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980420" evidence="2">
        <location>
            <begin position="33"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="190"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="586" mass="59632" checksum="972831FA60FC3CBA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX54</accession>
    <name>C7PX54_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBP_domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0453"/>
    <dbReference type="EnsemblBacteria" id="ACU69405">
        <property type="protein sequence ID" value="ACU69405"/>
        <property type="gene ID" value="Caci_0453"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0453"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_863110_0_0_11"/>
    <dbReference type="OMA" id="CADSSTI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982570" description="PBP_domain domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="30"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="33723" checksum="0EBF60FE870C86E7" modified="2009-10-13" version="1" precursor="true">MNQKTKKLAVIGAVGLFVLGAAGSAQADPSGAPQFRQLAGVGSDTTTPVMNALSNDLTVGGTKVIGSYDATGSTTIATQAGTTCSKIARPNGSGAGRTALLASLAAKDGCLQFSRSSSLTLTATGGAQLTYVPFALDGVTYAITGTDTLIPRNLDLATLQSIYTCDPTVVGTAPNFSITAMLPQAGSGTRSFWEGKMGITDADVVAGKYACITDKSNGQPIEEQDGRVLTDKAIIPYSIASYDAEESQTIQDVRGAAVLGAVGGVAAQQINSSFPVTREVYNVIPTADTATAPWSTTFVGSSSLVCADSSTITKFGFTVAPDCGSTTNVTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXB5</accession>
    <name>C7PXB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784761.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69466">
        <property type="protein sequence ID" value="ACU69466"/>
        <property type="gene ID" value="Caci_0522"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0522"/>
    <dbReference type="eggNOG" id="COG5450">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2615519_0_0_11"/>
    <dbReference type="OrthoDB" id="2064132at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="8443" checksum="0E7FDF691FB51108" modified="2009-10-13" version="1">MTKKLFDADEAILAEAQRQLGTATGKDTVNLALATVAGLKAKERDAALDYLREHFNELFDLSAVDPKKLTFPQPPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF5</accession>
    <name>C7PXF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate-binding CenC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786701.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2490"/>
    <dbReference type="CAZy" id="CBM16">
        <property type="family name" value="Carbohydrate-Binding Module Family 16"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71408">
        <property type="protein sequence ID" value="ACU71408"/>
        <property type="gene ID" value="Caci_2490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2490"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_4_1_11"/>
    <dbReference type="OMA" id="MNGHTDQ"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="CBM-cenC" evidence="4">
        <location>
            <begin position="50"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="526" mass="53813" checksum="8F0E75DC3065786D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI3</accession>
    <name>C7PXI3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_2518</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786729.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2518"/>
    <dbReference type="EnsemblBacteria" id="ACU71436">
        <property type="protein sequence ID" value="ACU71436"/>
        <property type="gene ID" value="Caci_2518"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2518"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="VPWLEPL"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="8">
        <location>
            <begin position="135"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="360" mass="39428" checksum="5060271258D1A116" modified="2009-10-13" version="1">MADAATFATETEPYRRELFAHCYRMLGSVLDAEDLVQETYLRAWRHYDKFEGRSSVRTWLYQIATNGCLTALAKRRDAERRVLPSGLGPPEDNTEAAVLEPDRRVRWVQPVPDALIAPESGDPAAVVAAREGVRLALVASLQHLPARQRAVLVLREVLALPASEVAEILQTSTASVKSALQRARATLREQAPAEDRISEPKAPQARAVLERYIKAFENADADALQQLLVQDATIEAPPMRAWFQGVQKCVPVLRHVMGEPGQWRMLPITGGANGSPAAAGYLRDEDGRYRPYGVVVLDVVGDRIARITSFGDPALLPVFGFENAPIGADAEVRLVCGYLEAFYVFEHGLMASQGAQFGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXM2</accession>
    <name>C7PXM2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786768.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2557"/>
    <dbReference type="EnsemblBacteria" id="ACU71475">
        <property type="protein sequence ID" value="ACU71475"/>
        <property type="gene ID" value="Caci_2557"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2557"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092792_1_1_11"/>
    <dbReference type="OMA" id="AGALWQM"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041483">
        <property type="entry name" value="TetR_C_34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17929">
        <property type="entry name" value="TetR_C_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="25099" checksum="7B3EA920E46FACEF" modified="2009-10-13" version="1">MTTPQFERARSAEAKQAREAAILEAAARLALEHGIRTVTLTDIAEAVGMHKSAMLRYFETREDIFLQLATTAWREWSASVRDQLARLSAGTGRGARRREWEQTAGEVAAALASSLVSRPLFCDLLAHTPLNLERNVSVDRVRAFKILAIAEVAAIAATLSTITPLSVNEATSVVTTATAMAGALWQMAAPRTTLRTLYESDPDLAHAVVDVEPRLTDILSALITGYAARSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXQ6</accession>
    <name>C7PXQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Crp/Fnr family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786802.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2591"/>
    <dbReference type="EnsemblBacteria" id="ACU71509">
        <property type="protein sequence ID" value="ACU71509"/>
        <property type="gene ID" value="Caci_2591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2591"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075053_3_4_11"/>
    <dbReference type="OMA" id="IAPHISQ"/>
    <dbReference type="OrthoDB" id="1596937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="24327" checksum="B1FFC702363D8A4D" modified="2009-10-13" version="1">MASSRFAQRLRGLVEDDSGVATTIRIPRGGHVFNCGDHDDDVYMIETGQVKTVTFSRDGKQCLLSIYAPGDVFGELCQASAGRLETATAMRPTILRRIRSGRFRAALADQDLLEAFLAYLALRVSEQQQIITNLVTMDSERRLAAVLLTLADKIGKRHSTGTSIEQRITQEELSDMVGTTRSRVGYFLKRFAEAGLVSRHPGAFLVVDENGLADYLETAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXS4</accession>
    <name>C7PXS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2610"/>
    <dbReference type="EnsemblBacteria" id="ACU71527">
        <property type="protein sequence ID" value="ACU71527"/>
        <property type="gene ID" value="Caci_2610"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2610"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_3_11"/>
    <dbReference type="OMA" id="FANIRMG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="108"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="37450" checksum="B0245B09A4EECAB8" modified="2009-10-13" version="1" precursor="true">MSTPLTESVPAAQSAGTDPRDRHRDRRDRRGHLRVPRRGGHRAAWRVAGFVIPAWIYILCFYVYPLFANIRMGFQDYSVSSFYSGSAPYVGLRNYTSLWHNPQFGSIVTNTLLFTIGSLVFQFGIGLALAVFFRRKFPLNGVLRSLLLVPWLLPLVVSGTVWRWMMYADSGVLNQVLLNLHVIGHPVPWLVSTTWSLTAVTLVNIWVGIPFNMVILYGGLQGVPEQLYEAAAIDGANAWQRFRRITWPMLRPVTLVVLTLGLIYTVKVFDVIQIVSQGGPANSSQTLTTYAYNLSFQQLEFGKGAAVGNLLILVAIVFAFLYLRSVREPEGRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV4</accession>
    <name>C7PXV4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793143.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4552"/>
    <dbReference type="EnsemblBacteria" id="ACU73414">
        <property type="protein sequence ID" value="ACU73414"/>
        <property type="gene ID" value="Caci_4552"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4552"/>
    <dbReference type="eggNOG" id="COG1893">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_6_1_11"/>
    <dbReference type="OMA" id="WEKWVFL"/>
    <dbReference type="OrthoDB" id="427052at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="178"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="31748" checksum="A2A8FBEFDEAB903A" modified="2009-10-13" version="1" precursor="true">MRILVVGAGATGGYFGGRLAQAGRDVTFLVREGRARTLRERGLRIVGLGEQTVLEPRLVTADTIDGPYDLILVTVKESGLTGAVADLAPAVGPDTLIVPVLNGMRQIDVLVERFGEQAVLGGIAYVMTTIDADGDILRLAGMHRLAYGRRDGSVDDQVRAVHAALSDAGFDTALSERILGAMWSKWTFIAALGAVCVLGGGTVGEVGAVPGGTALAEAVLAEAASVAAAAGHPVSEQEIGVYRGMLTAQGSDDTSSLFRDLSAGLPVEAEQIFGDLVARAEALDVAVPSLAAVAVRLRVHNARVAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYB8</accession>
    <name>C7PYB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795137.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6562"/>
    <dbReference type="EnsemblBacteria" id="ACU75408">
        <property type="protein sequence ID" value="ACU75408"/>
        <property type="gene ID" value="Caci_6562"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6562"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="FYSTHIV"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="31198" checksum="BCA744D37512E121" modified="2009-10-13" version="1">MAGRGRALAEADQATKRYGSFTAVEAVSMRVDPGEIVGLLGSNGAGKTTLIRMLLGLTRVSDGTVAVFGQAPDRTTRQRLGYVPQGLGLWETLTVQENIAFAAAAFGTDATATTLTPGLLKARDQQVSAIGLGLQRQLAFTIALAHRPKLLVLDEPTSGLDPLSRARLWDTIHDQADDGAGILVTTHYMQEAQQCDRLILMSHGQSVAEGTEAAIIGDTTACEVDTSGDQWAAAFAALDAAALPVTLAGRTVRLADTPQDTIHDTLAQAGIDARIREVPATLEEKMTVIERVVTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYD8</accession>
    <name>C7PYD8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6582"/>
    <dbReference type="EnsemblBacteria" id="ACU75428">
        <property type="protein sequence ID" value="ACU75428"/>
        <property type="gene ID" value="Caci_6582"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6582"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_0_0_11"/>
    <dbReference type="OMA" id="IRSEWTG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="759"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1076" mass="114346" checksum="291242EB1C9A886D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ73</accession>
    <name>C7PZ73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0694</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784924.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0694"/>
    <dbReference type="EnsemblBacteria" id="ACU69629">
        <property type="protein sequence ID" value="ACU69629"/>
        <property type="gene ID" value="Caci_0694"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0694"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011855_0_0_11"/>
    <dbReference type="OrthoDB" id="881553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1162" mass="122967" checksum="261071CA9324E96F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA3</accession>
    <name>C7PZA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="2">2.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2644"/>
    <dbReference type="CAZy" id="GT20">
        <property type="family name" value="Glycosyltransferase Family 20"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71560">
        <property type="protein sequence ID" value="ACU71560"/>
        <property type="gene ID" value="Caci_2644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2644"/>
    <dbReference type="eggNOG" id="COG0380">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_7_1_11"/>
    <dbReference type="OMA" id="VGVFPCG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="PTHR10788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="57560" checksum="59E6F842C6886C6A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE5</accession>
    <name>C7PZE5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="2">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2687"/>
    <dbReference type="EnsemblBacteria" id="ACU71602">
        <property type="protein sequence ID" value="ACU71602"/>
        <property type="gene ID" value="Caci_2687"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2687"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026434_0_2_11"/>
    <dbReference type="OMA" id="LDPTMMY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="46775" checksum="6C7D4C6ED71C15DD" modified="2009-10-13" version="1">MEQSLDNPAVGVTAARQSVPFAVAAQPGGGLLRAKLAERLFRSATARLPLTVRYPDGRVEGAGRDGSPVMVLHDPRGFFHRLGTARLIGFGESYQAREWDSTQLAELLAVFAAELPRLVPAPLQSLRRAFDLRRPGGAANSLRGARRNIEHHYDLSDELFELFLDETMTYSAALFHQNPLGRPDGGFATLADAQCRKIDRLLDLCGVGLGTRLLEIGSGWGSLALRAAARGAQVTTITLSSNQHDAVRRRADAAGLGDLVDVRLMDYRAVQERYDAVVSVEMIEAVGREHWPTYFRALRRLTAPGGRIGLQAITMPHERMVAAAGSQTWITKYIFPGGIIPSQTAIDSESQAAGLHMLHDFSFGRHYAHTLRLWRDRFSEQREAVAALGFDETFRRTWELYLAYSEAGFAAGYLDVHQMVFATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZQ8</accession>
    <name>C7PZQ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793302.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4712"/>
    <dbReference type="MEROPS" id="S53.008"/>
    <dbReference type="EnsemblBacteria" id="ACU73573">
        <property type="protein sequence ID" value="ACU73573"/>
        <property type="gene ID" value="Caci_4712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4712"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_3_0_11"/>
    <dbReference type="OMA" id="PQWSALI"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982729" evidence="1">
        <location>
            <begin position="42"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="2">
        <location>
            <begin position="90"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="429" mass="42029" checksum="2B513708A377A21E" modified="2009-10-13" version="1" precursor="true">MIDRFTPPAARFLRRSGARVAALGAAFALVLAVTAPAGAEAAGASAAAGARPAASPIVPFGCAKVVTGKAHCLGQGRLIPNASGSPTSSGLKPADLIAAYKLAGTNGAGRTVAIVDAFDDPNAAADLAAYRSAYNLPACTAASGCFQKVNQSGQASPLPAADYGWAEEESLDLDMVSAICPGCHILLVEASGADTASLTTAEDTAAAAPGVVSISNSWGAAEDSSTLAADAHFNHPGKAITASSGDSGYGVSWPAASQYVTAVGGTSLSAASNARGWTETAWSGAGSGCSVQEPKPSWQTDSGCAHRTVADVSAVADPNTGVAVYDTANSCGGGAFCDLLLALGLATGADGWVQVGGTSASSPIIASVYALAGNTGSLVYGSQPYKNAGSLFDVTSGNNGTCTPAYLCTAGTGYDGPTGLGSPNGTGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ7</accession>
    <name>C7PZZ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6644</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795219.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6644"/>
    <dbReference type="EnsemblBacteria" id="ACU75490">
        <property type="protein sequence ID" value="ACU75490"/>
        <property type="gene ID" value="Caci_6644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6644"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="IVRELCH"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="110"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="171"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="42097" checksum="2EA356168A00BF86" modified="2009-10-13" version="1" precursor="true">MDFRPLRTARARLTALFGTLFLAAGAVLLGIANILVDRSTDTAVYSPQPQPPAPTGTLFQSDRIPAQGRDLQAQLRHLHSYDVHQFLIRSGIALGATALVAVVLGYFVAGRALRPVRTITVKARMISAHNLHERLALAGPADELRELAQTFDDLMDRLEQAFHAQRQFIANASHELRTPLARQRAIAEVALDDPDPTIGSLRAAHERIIAAGAHQEAIIEALLALARGQAGTDRHDRIELAAVADQAVAACRARTSLRAPDRIAVHTSLAPAPVIGDARLIERLAVNLVDNALRYNLEGGQVWVSTYVADGRSVLTVSNTGSPIPADAIDRLRQPFRRLETDRVGRRDGLGLGLSIVQAVADAHRGIVAIRPRPEGGLSIEVAFPLSPAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q000</accession>
    <name>C7Q000_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795222.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6647"/>
    <dbReference type="EnsemblBacteria" id="ACU75493">
        <property type="protein sequence ID" value="ACU75493"/>
        <property type="gene ID" value="Caci_6647"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6647"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_578611_0_0_11"/>
    <dbReference type="OMA" id="ISIASCH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982655" evidence="3">
        <location>
            <begin position="39"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="179"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="488" mass="50705" checksum="61F935F1129682A8" modified="2009-10-13" version="1" precursor="true">MSRSKTIPRPLRYAAIVSACAMLTATLVSQPAIGVGSAHTDTAPPTPCAPPTAPGPPPLTPTTATTIEQAYYCVFAHYYNAAALDDRPLLDGAFAGLTQSLDHLGIDQPDATAPALTGNREQDWTAFAAIYQQIVDQLPTDPNLRQQVASATMQGMIAALDDNHAGWSRPVMPPGFQPGDQYGIGLVTSPTGPLLSGAPAEARPPLFVSAVLGGPAAAQGLRPGDVIDSVDGQAPFVDGVPSPGVEALLDQRYPQSDRVQLKVHRPADGRSWTVTLKPELYPMSAAANQPVSASLLSDHIADVQLHSFLPGAADTVLADVARMRAGGTLNGLVLDLRGNGGGDVEEVSRLLGAFKHQGIWSFDCDSPDTCDIPHRTDDTVPLLGIPLVVLTDRGCASACDAFSGAVKDLRLGRIVGTRTAGVVAGPAAGFVLDDGSFLGLPAGHELGADHEMLNGIGVAPDDYQLTTPADLSTGHDHVLAEAVRLLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q021</accession>
    <name>C7Q021_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Squalene synthase HpnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6668"/>
    <dbReference type="EnsemblBacteria" id="ACU75514">
        <property type="protein sequence ID" value="ACU75514"/>
        <property type="gene ID" value="Caci_6668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6668"/>
    <dbReference type="eggNOG" id="COG1562">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037269_0_0_11"/>
    <dbReference type="OMA" id="DYCRYSA"/>
    <dbReference type="OrthoDB" id="1449625at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017827">
        <property type="entry name" value="HSQ_synthase_HpnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480:SF17">
        <property type="entry name" value="PTHR31480:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03464">
        <property type="entry name" value="HpnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="32285" checksum="F9556840F9673A8A" modified="2009-10-13" version="1">MLKASRLDTASGPGPRAASATRPGAGDPAMPPERTIRENFPVALRILPARHRAALGAVYRYARLIDDIGDEAPPADRGRLFDLVDRDIDRIFAGTAPELPALRAIGAVAREHGIPEAPLRKLVQANRQDQEIHRYATWDQLVEYCALSADPVGHLVLHVFDAASPERLALSDHICTALQVIEHCQDVAEDFADGRVYLPATDLKLFGCTDADLGAETTPTRLRGVVARNADRAAALLDEGAPLIGKLDGWARVAVAGYLAGGRATLAALSGGAYDVHAARLRPSRARTLGEALLILGRDVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q073</accession>
    <name>C7Q073_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="6">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795295.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6720"/>
    <dbReference type="EnsemblBacteria" id="ACU75566">
        <property type="protein sequence ID" value="ACU75566"/>
        <property type="gene ID" value="Caci_6720"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6720"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="HRRILYV"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="374" mass="39764" checksum="685798FAF1F40EA8" modified="2009-10-13" version="1">MPTPQGKPSRTPRAPRTPRETDGPKRATVQEVAEAAGVSTATVSRVLNGNYPVATETRRKVEQAVRTLGYVVNAHARALAGSRTRTVGIIVQDIIDPFYTFIAHGVQRQAAEDGKLCLVCSTYGVVGGELDLIDALHEQRADAVILVGGGVDDPAYRRKLADRARALGREGSWLVLCGRPALEDGVPAGVVDYDNTGGAHAITEYLLGLGHRRILYVGGPEQLSVHQARVAGFRRAHASRGLEVDERLIQPGAFSRRFGYERVAQLLRDGSAGEFTAVFGANDGVAVGAMQALREAGLRVPRDVSVVGYDDIPLAAEVTPALTTVHLPLEQMGREAVRLAVALRGESDGPTGTRHVGTHVVIRDSTAPPPAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q094</accession>
    <name>C7Q094_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major intrinsic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797152.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8608"/>
    <dbReference type="EnsemblBacteria" id="ACU77427">
        <property type="protein sequence ID" value="ACU77427"/>
        <property type="gene ID" value="Caci_8608"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8608"/>
    <dbReference type="eggNOG" id="COG0580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_8_0_11"/>
    <dbReference type="OrthoDB" id="1744995at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="PTHR19139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="24967" checksum="2C0E3FDC6EBA602D" modified="2009-10-13" version="1">MTPPLARRALAEFLGTALLVAVVVGSGIMATNLSHDVGLQLLANSTATVFGLTVLILIFGPISGTHFNPVVTLADYVLSRRSGGGTDVRTVAVYIPAQVAGGIGGTVLANLMFNLPVVTASTHTRSARYLWLGETVATAGLVLLIFSLVRSGRGTLVIAPAVGAYIGAAYWFTSSTSFANPAVTIARAFTNTFAGIAPGSVAAFVAFQVVGAAIGVALVAVLYPVAQHGDTESLAEAEQVPAAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0H5</accession>
    <name>C7Q0H5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8693</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797232.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8693"/>
    <dbReference type="EnsemblBacteria" id="ACU77508">
        <property type="protein sequence ID" value="ACU77508"/>
        <property type="gene ID" value="Caci_8693"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8693"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="PTHYARE"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="205"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33446" checksum="3679705F9A1C627D" modified="2009-10-13" version="1">MDILSDALDALRTGRPGVARTEARAPWAIRYRPVAGAGFHIVAEGACHLVPLHGQPLALSVGDIVFLRRGSGHMLCDTLATPPVDFIPERASAASPLGRFTVPGDGAATVLLCGAYPLDVERRHPVLGDLPDVIHLPAGPGRHPALRSAVEQLCAEIQAPQPGSDTVVATLVDLLLLYILRSWYAEQPDEQARGWAAALDDPLVAPALQAIHDDPGHAWTVESLGERAGLSRAAFARRFATVVGEPPLTYLTGWRMVTAARMLRQSGDPLSAIAERNGYTSEFAFAKAFKRQFGLPPGAYRRELRTAGDPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0P0</accession>
    <name>C7Q0P0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0733"/>
    <dbReference type="EnsemblBacteria" id="ACU69668">
        <property type="protein sequence ID" value="ACU69668"/>
        <property type="gene ID" value="Caci_0733"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0733"/>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_2_0_11"/>
    <dbReference type="OMA" id="TKGQPDP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="29506" checksum="1E8DA53E606AB71F" modified="2009-10-13" version="1">MRDVAYSVYERRLAARLHTDVQRGKKKVPRHIGVIMDGNRRWAKQMGEQIATGHQRGADKIHEVLDWAEEAGVETVTLWLFSTDNFNRPADELTDLLRIIEGSVRSLADTGRWRVHPLGALDLMPADFARHLKEIEEQTRDNPGIHVNVAIGYGGRREIADAVRSLLADAAARGTSIEDLVQMLDVEHITEHLYTQGQQDPDLIIRTSGEQRLSGFMLWQSAHSEFYFCEAYWPAFRKVDFLRALRDYANRHRRYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S5</accession>
    <name>C7Q0S5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protease inhibitor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I16 (SSI) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784998.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0768"/>
    <dbReference type="EnsemblBacteria" id="ACU69703">
        <property type="protein sequence ID" value="ACU69703"/>
        <property type="gene ID" value="Caci_0768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0768"/>
    <dbReference type="HOGENOM" id="CLU_1774030_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="SSF55399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981370" evidence="3">
        <location>
            <begin position="28"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="SSI" evidence="4">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="15092" checksum="7B68C365EB5E0E9F" modified="2009-10-13" version="1" precursor="true">MRRLAAAAVTALLSAAALTAGGGAAQAAAGVPAHKLGSLHLKRVDAKNHKTYTAYLVCTSVSRHGAAPVIHGVGSIKDPSSACRELAEVHGRPAALAVHPLWLAPSIVAPVTVRIDGTWQGRKVTWSHTYTNGAWLAKATGDVFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1E7</accession>
    <name>C7Q1E7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4815"/>
    <dbReference type="EnsemblBacteria" id="ACU73676">
        <property type="protein sequence ID" value="ACU73676"/>
        <property type="gene ID" value="Caci_4815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4815"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_0_2_11"/>
    <dbReference type="OMA" id="CEFFQIA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="796"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="866" mass="92272" checksum="7896A43DF3F69147" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1L9</accession>
    <name>C7Q1L9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fumarate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4888"/>
    <dbReference type="EnsemblBacteria" id="ACU73748">
        <property type="protein sequence ID" value="ACU73748"/>
        <property type="gene ID" value="Caci_4888"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4888"/>
    <dbReference type="eggNOG" id="COG0015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030949_3_3_11"/>
    <dbReference type="OMA" id="HRATPMI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="2">
        <location>
            <begin position="475"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="568" mass="58250" checksum="7CC3ED5DD39EB4F7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V7</accession>
    <name>C7Q1V7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795386.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6817"/>
    <dbReference type="EnsemblBacteria" id="ACU75658">
        <property type="protein sequence ID" value="ACU75658"/>
        <property type="gene ID" value="Caci_6817"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6817"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_4_0_11"/>
    <dbReference type="OMA" id="QGSAWTT"/>
    <dbReference type="OrthoDB" id="1470522at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="113"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="28623" checksum="599E3A00B241D6F2" modified="2009-10-13" version="1">MERIRAPFVDADGVAHYRNITVSRIQGFRPLHADLRVPPGEGPKPLIAFLHGGAFWGGSRVDLPGPLDELESPGFYERLLTRGYAVADLDYRLSGEAVFPAQLEDVESALRRLREAAAELGLDAARFAVWGESAGGTLGALAALDKDSGVPIHAVVDWYAPADFVEGADGFDIPGNPIYALLGGQRELASAASPTRQVHAVAPPFLIMHGAADALVPYSESENLAAALRSVGVRADLVPVEGAGHVMEGASDIGALVDQVLDFLDEVLAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2F5</accession>
    <name>C7Q2F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785092.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0864"/>
    <dbReference type="EnsemblBacteria" id="ACU69797">
        <property type="protein sequence ID" value="ACU69797"/>
        <property type="gene ID" value="Caci_0864"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0864"/>
    <dbReference type="eggNOG" id="COG1063">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_11"/>
    <dbReference type="OMA" id="GAWAEYT"/>
    <dbReference type="OrthoDB" id="1859760at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="14"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="35355" checksum="23C5C6C9B1694C14" modified="2009-10-13" version="1">MATMRAARLNLSTGTLSVEDVEKPAPGTGEVLVKVEAAGVCLSDVHLVRGYFAKPRLLVGDTVTLGHEIAGTVAEVGPDVTAWKPGDRVVLQAGEVRDGQVWTRGVDYDGGWADFALARQDTLVALPDSIPFEQGAIIPDAVSTPWGAITATAHVGPAQSVGVWGIGGLGAHAVQLLRAIGACPIIAIDPSEAARERALAFGADIALDSADPELRSAIRAATGGVGLEYAFDFAGVTPVRDQALRQLAPGGKLVLVGLSGQPITIENSTRFQSAQYQLLGHYGSPEESVAQLIRLEAGGRLNLARSISGVMGLEEAAEAVERLEKKVGDPIRIVLRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2R0</accession>
    <name>C7Q2R0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2893"/>
    <dbReference type="EnsemblBacteria" id="ACU71802">
        <property type="protein sequence ID" value="ACU71802"/>
        <property type="gene ID" value="Caci_2893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2893"/>
    <dbReference type="HOGENOM" id="CLU_1881989_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046214">
        <property type="entry name" value="DUF6247"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19760">
        <property type="entry name" value="DUF6247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="135" mass="14877" checksum="079689FAFDEFE910" modified="2009-10-13" version="1">MRGKVTGMSAQPIHSPRVMPKPARTPAAIRAVLVNAGEQGLVERFDAALDCAYTEAREANSLEPLNEMLTWWWAESISWCDPAKHKAFLAKVEGWRVNGIPDSERANPDDVLAILEAKGASRDALDKLRSLAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q322</accession>
    <name>C7Q322_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787207.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3005"/>
    <dbReference type="EnsemblBacteria" id="ACU71914">
        <property type="protein sequence ID" value="ACU71914"/>
        <property type="gene ID" value="Caci_3005"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3005"/>
    <dbReference type="HOGENOM" id="CLU_1145576_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26959" checksum="AE8BBA3A464C8817" modified="2009-10-13" version="1">MSETKIHVVCDPDQETVRKLLGEVTRLRDANEVATALVAEFKTLRAENEKLATRVGWAHEARKSAEAEVERVKTLNRDVAKRLMRTMERATAAENEVKHLRARIADEIGSIGQEMEIKQLEGKSEPGSPTAPEPASDATTSWTPEDVPPVLVQAAHDGWWSAAGQGLDWEAWLRVEIAAVLTQLGLREEFGVQSEDSERAQPCDDLQHASHLADRYSRFLTFGGGTIQHHVVRHLATSWERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q355</accession>
    <name>C7Q355_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-arabinofuranosidase B catalytic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4931"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH54">
        <property type="family name" value="Glycoside Hydrolase Family 54"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73791">
        <property type="protein sequence ID" value="ACU73791"/>
        <property type="gene ID" value="Caci_4931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4931"/>
    <dbReference type="eggNOG" id="COG3693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029332_2_0_11"/>
    <dbReference type="OMA" id="GNACWFG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031221">
        <property type="term" value="P:arabinan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019566">
        <property type="term" value="P:arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="PTHR39447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980563" evidence="1">
        <location>
            <begin position="40"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="373"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="50404" checksum="92AEB169D728E810" modified="2009-10-13" version="1" precursor="true">MFRSIVTGVRRPLRPLLMLAFAAILAVAGIQVGAGKARAATSLPCDVYASGGTPCAAAYSTVRALFASYNGPLYQVQRASDNSRTDVGLLAAGDYANGAAQVSFCAGTSCTITKIYDQTSHHNDMPISSGGFWKGPGPNGSDVGADASALPVTVNGHAVFGVKVHPGVGYRIDNTVGVPTGAQPEGVYMVTSSNYYNSQCCFDFGSAETDHKDDGNATMNAIEWGNACWFGGCTGSGPWVEADLENGMFSTNRGPNNADNPGVSHPFVTAWEKNNGTSNFTLKDGDATTGGLTTTYSGALPNNYSPMKVQPDVELGTGGDNSNGGQGEFFEGAVTTGFPSDATENSVQAAITSAGYSAPAPPPGGALHAVGAGKCLDVPNSSTTGGTQLQIYSCNGQANQSFARTSAGAISVTDAGVTDCLDANNKGTTNGTKVIIYPCNGQSNQQWTFNSNGTITGVQSGLCLDVTGASTANGALVELWACNGGSNQQWTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3C9</accession>
    <name>C7Q3C9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73865">
        <property type="protein sequence ID" value="ACU73865"/>
        <property type="gene ID" value="Caci_5005"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5005"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_44_0_11"/>
    <dbReference type="OMA" id="RAPKGDM"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24859" checksum="6C43802B95890C65" modified="2009-10-13" version="1">MPPVVGLGAEGVGAMVEAAPVRRRVRSRLPAAKRRPQIIKVTSELIAERGYWGLSMQDVADQCGLTVPGVLHYVGSKVGLLVAVLEQRDVEDAQSLREQLGVAEDEVPDEWSGGGPEGVDLRQLCAATMRRNARQPQIVRLFAVLEAESLDPGHPAYDYFVARQARVVSSFAALAGPFTAAPEALARQIVAMMDGLQLQWLRAQQSIDLVQEWEAAAEMLFGPHTDAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3F5</accession>
    <name>C7Q3F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6882"/>
    <dbReference type="EnsemblBacteria" id="ACU75720">
        <property type="protein sequence ID" value="ACU75720"/>
        <property type="gene ID" value="Caci_6882"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6882"/>
    <dbReference type="HOGENOM" id="CLU_3181615_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="46" mass="4742" checksum="2BD8D19AE0F5EBE1" modified="2009-10-13" version="1">MDLTIIDELFDGPLATAVPTQSQALAEKAPGDADGEDKGDHCSVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3I3</accession>
    <name>C7Q3I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent OLD family endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795476.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6911"/>
    <dbReference type="EnsemblBacteria" id="ACU75748">
        <property type="protein sequence ID" value="ACU75748"/>
        <property type="gene ID" value="Caci_6911"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6911"/>
    <dbReference type="eggNOG" id="COG1106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023912_1_0_11"/>
    <dbReference type="OMA" id="MIAESAY"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01026">
        <property type="entry name" value="TOPRIM_OLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034139">
        <property type="entry name" value="TOPRIM_OLD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="1">
        <location>
            <begin position="1"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="669" mass="75055" checksum="B95373DCE3F076EE" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Q7</accession>
    <name>C7Q3Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid/amide ABC transporter substrate-binding protein, HAAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797389.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8852"/>
    <dbReference type="EnsemblBacteria" id="ACU77665">
        <property type="protein sequence ID" value="ACU77665"/>
        <property type="gene ID" value="Caci_8852"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8852"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_603763_0_0_11"/>
    <dbReference type="OMA" id="EGMIFAK"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980582" evidence="1">
        <location>
            <begin position="30"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="56"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="448" mass="47475" checksum="A16A11497663A542" modified="2009-10-13" version="1" precursor="true">MRRIFLLGAGLSLLATAACGTRLPDSAFASQSPGAAGTSGAPAANPASDVGVTPTSIKIGMIDSVDSLLGPDTFSGPMYGAQAFFKALNAAGGVNGRKIDIATCDDEGVGGTDVSCAHTLIDQDKVFAFSGNSIFQYDAASYVSAKGVPDIGGEPISNAYDQYPHLYSIYGSDYPRDGKSIGWQGKLYSSTEPEHYAKTVLKAHVAGLVSYNQADSARYAAYEAQALRAEGFTVVPEQLDIALADFDSAALDMKNKGVDVVFDTIDTDGNARLCKAIEDTGVPIKAKMTTVQSWDATVATTYKDAPKCRNLLYANSSDANYEDVSNPAVKAFRDAMAKYFPDRQGKLSEWEIDGWASAQWLTDAVASCGADVTRVCVEKFMNSGKPYDAHGIITPAAFEVKAPTGTTHACFNVAQWQDSANGGQGGWVTRVPDMDTNCYDVPQVSYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4A0</accession>
    <name>C7Q4A0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conserved repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1034</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1034"/>
    <dbReference type="EnsemblBacteria" id="ACU69960">
        <property type="protein sequence ID" value="ACU69960"/>
        <property type="gene ID" value="Caci_1034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1034"/>
    <dbReference type="eggNOG" id="COG2373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_241291_0_0_11"/>
    <dbReference type="OMA" id="YTLTPCA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046022">
        <property type="entry name" value="DUF5979"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19407">
        <property type="entry name" value="DUF5979"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980586" evidence="3">
        <location>
            <begin position="30"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1566"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5979" evidence="4">
        <location>
            <begin position="1329"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5979" evidence="4">
        <location>
            <begin position="1435"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1529"/>
            <end position="1550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1597" mass="160651" checksum="1A9D6CD07E380635" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4D7</accession>
    <name>C7Q4D7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Indole-3-glycerol-phosphate synthase</fullName>
            <ecNumber evidence="3">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1071"/>
    <dbReference type="EnsemblBacteria" id="ACU69997">
        <property type="protein sequence ID" value="ACU69997"/>
        <property type="gene ID" value="Caci_1071"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1071"/>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1076420_0_0_11"/>
    <dbReference type="OrthoDB" id="1789381at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IGPS" evidence="6">
        <location>
            <begin position="85"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="26855" checksum="E07EEA07578B9020" modified="2009-10-13" version="1">MQPRAPYQSTQSAAAGADAPLEQIKKLALSRPVEYGALDRLCTGGIAVIAEIDPTDPAAADLVSRFEDGRVRAIAFSAGSLTARAERMVHIRTHTHVPLLCLEPADTSHQLWQARACGADLIVLRAATLSDLALFSLVERAASIGMEALVEVRTGADLVRALRAQARGVLLRPSADAIPGTPQADLHDLLSMVPDGVVKVAECGPGGRSDLIACARNGADAVLLGARLLTCPDPGSVVADLAAMGAHPALSRRGSRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4V8</accession>
    <name>C7Q4V8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5046"/>
    <dbReference type="EnsemblBacteria" id="ACU73906">
        <property type="protein sequence ID" value="ACU73906"/>
        <property type="gene ID" value="Caci_5046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5046"/>
    <dbReference type="HOGENOM" id="CLU_2768239_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982528" evidence="1">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="6365" checksum="8B66FD247E01E292" modified="2009-10-13" version="1" precursor="true">MSETAYVTVRSRATIAFSALFLSAVALAAGSATTLGHGAGAGSAASAGAARSAAVSTVAGSVPCSMCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q594</accession>
    <name>C7Q594_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795591.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7033"/>
    <dbReference type="EnsemblBacteria" id="ACU75863">
        <property type="protein sequence ID" value="ACU75863"/>
        <property type="gene ID" value="Caci_7033"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7033"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_0_11"/>
    <dbReference type="OMA" id="FHEAFDY"/>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982535" evidence="4">
        <location>
            <begin position="44"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33141" checksum="B45A7EBA750C56A0" modified="2009-10-13" version="1" precursor="true">MLFRTAASRRRRRRAVPAGAAVALVAALTLTLSGCLKQSDEHASDGRLDVVAGFYPFAFLAERIGGEHVAVRNLTKPGAEPHDLELTPSQVGAVSKADLAIYEKGLQPAVDAAVTQNKPKAALDTATVVHLEEHGDLGEGSAHSADPHVWLDPVNFGRIADAVSAKLQQVDPGNAAGYRANQAALDSQLTALDADYRAGLAHCQRKDVVTSHAAFGYLAERYGLVQVPLAGLSPDDEPSAAHLAKIQHLIKTEGVTTVFFETLASPKTARTLASDTGTKAAVLDPVEGVKNASAQDYLSIMRDNLAALRTALGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5B2</accession>
    <name>C7Q5B2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purA</name>
        <name evidence="8" type="ordered locus">Caci_7051</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7051"/>
    <dbReference type="EnsemblBacteria" id="ACU75881">
        <property type="protein sequence ID" value="ACU75881"/>
        <property type="gene ID" value="Caci_7051"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7051"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_4_0_11"/>
    <dbReference type="OMA" id="DGRHHTF"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="55"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="357"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="434"/>
            <end position="436"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="48368" checksum="9C14DA9131435200" modified="2009-10-13" version="1">MDLIGMKHAIVVDLGYGDAGKGSTVDWLCSPGHAEPRAASRIRAVIRFNGGAQAGHNVITPDGRHHTFAQFGAGTFHGVPTHLSRFMLVEPFALAAEAAHLAELGIGNPFALLSADSRALITTPYHRAANRVRESARDRTPGSARHGTCGMGIGETVSFSLAVSPDKPPRVGDCRDRATLVRKLTALRARIAADLELSGLRLPADLPSPEFCADVYQAFAQRVRIVDEECSGYLAALLDSGPCVFEGAQGVLLDEWYGFHPHTTWSTTTFANAEELLKESGQETGNAARLGVVRTYSTRHGAGPFVPEDAALAPHLPEPHNETGTWQGAFRIGHFDAVAHRYALDVCGGADALVVTHADARADGRRLCRAYQASADVPAMEKLPRSLMPDLDYQRLLTKTVSSCTPVYDDGPRDQRDWPDVIEEALGTPVGVVSSGPTWREKAARLPCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5D0</accession>
    <name>C7Q5D0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis PhzC/PhzF protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7069"/>
    <dbReference type="EnsemblBacteria" id="ACU75899">
        <property type="protein sequence ID" value="ACU75899"/>
        <property type="gene ID" value="Caci_7069"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7069"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098567_0_0_11"/>
    <dbReference type="OMA" id="YAWAWED"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25127" checksum="54047C1D456A61E8" modified="2009-10-13" version="1">MSMMADVHIVRVFTDAHGLFGNNLGVVLDAAHLDAAAGRKLASDLRFSEVVFVDDVEQARLRIFTPAAELPLAGHPLVGTSWLLSRLTGREVKALRPQKAAEVPTWSEGGRVWIRGRISDAPDWGLVEVADEAAVETLAVPPAPEYRRHQFWAWTDEPGGVMRARVFAADSGIEEDEATGSAAMRQVGALGRALVIRQGWGSEILARPAAVDGWAEIGGRVAGDGMRTVTVGGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5K6</accession>
    <name>C7Q5K6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797541.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9004"/>
    <dbReference type="EnsemblBacteria" id="ACU77817">
        <property type="protein sequence ID" value="ACU77817"/>
        <property type="gene ID" value="Caci_9004"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9004"/>
    <dbReference type="eggNOG" id="COG0343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_958578_0_0_11"/>
    <dbReference type="OMA" id="WAAPQDW"/>
    <dbReference type="OrthoDB" id="1020584at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="30723" checksum="C7B7FD3CA5A40F89" modified="2009-10-13" version="1">MRFYLGCHQPAWLAATDIPLFISHRRLAHRRTLPRALGPWCLDSGAFSEIQQYGRWTITAEQYAAAVRRYVQEIGGLQWAAQMDWMCEPVVIGGGQVGRSRFVGTGLSVEAHQQLTVDNYLRLRDIAPDLPIVPVIQGWQRDDYLRCVDLFARSGVDLEHEPVVGLGSVCRRQGTGEIRAIVESVAALRIRLHGFGVKTAGLGIYGRHLASADSLAWSYQGRYRPGCRVGHRTEANCARWAAEWRQKIIRTSETGLPRDSSARRRRRCGTGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Q7</accession>
    <name>C7Q5Q7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease P protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_9055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9055"/>
    <dbReference type="EnsemblBacteria" id="ACU77868">
        <property type="protein sequence ID" value="ACU77868"/>
        <property type="gene ID" value="Caci_9055"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9055"/>
    <dbReference type="eggNOG" id="COG0594">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117179_4_1_11"/>
    <dbReference type="OMA" id="THHVVIR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11362" checksum="327E8AEB5596E70F" modified="2009-10-13" version="1">MRRSADFGAAVRGGRRAGRTTLVAHLAVPSDPPPAADAAVLAGFVVSKAVGPAVVRTAVKRRLRHLVRSRLDQLPPGSRLVIRALPAAAEADSATLGADLDSALRKLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D5</accession>
    <name>C7Q6D5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative two-component system sensor kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3234"/>
    <dbReference type="EnsemblBacteria" id="ACU72141">
        <property type="protein sequence ID" value="ACU72141"/>
        <property type="gene ID" value="Caci_3234"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3234"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1222959_0_0_11"/>
    <dbReference type="OrthoDB" id="1879123at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="181"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="24135" checksum="5246C7D23E52BA4A" modified="2009-10-13" version="1">MVHPERLPGWLPDALVGVVTATLLVVISAHIPAGSDSRAVDAVQYILLVAGGGCMALIRWRPQTAAALATFILCVEVARQYPDGPIWAVGWISLAGVSWQTSRRAALGWAGVMLAALTLAAVVFGSSGLVLPLIFLGWSAAAILAGDALRDRRERLQALRERARFLEMTQEEVALRRVAEERLRIARDLHDSVAHAMATINVQAAAAAHVIERRPQAAGECPPCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6E1</accession>
    <name>C7Q6E1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3240"/>
    <dbReference type="EnsemblBacteria" id="ACU72147">
        <property type="protein sequence ID" value="ACU72147"/>
        <property type="gene ID" value="Caci_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3240"/>
    <dbReference type="eggNOG" id="COG1426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055817_1_1_11"/>
    <dbReference type="OMA" id="SKGASWW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043917">
        <property type="entry name" value="DUF5753"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19054">
        <property type="entry name" value="DUF5753"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="34436" checksum="2F6B2F17C2654968" modified="2009-10-13" version="1">MTERATLRHRRIGAALRAHRVNAGLTLERVAHRLTPADAMSAAKISRIENGQYAVNPHDVRALCRVYDLDQSATDELVDQASQALRRTWWQEGEAGVLPAPFQRYLEYEDTCVALDVFAPVFVPDILQTAAYTRMLIAGLWPDKNPGERQALASVLTRRQSRLAVEAGPRVQVVLDAHAVLRSWGDRSVAVRQAAYLLEVSRHPRTEVRVIPDGRVYPGAHTGFTLMTLGSGDKQGKQAKQVKQVKQPAPGAPAKPAEHVGFVGGVVGWCLVDGGDEIDRYTLTFQQQRAAALGPEETRRWLRLAIKSMGGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X2</accession>
    <name>C7Q6X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="6">3.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795713.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7156"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75985">
        <property type="protein sequence ID" value="ACU75985"/>
        <property type="gene ID" value="Caci_7156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7156"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4945">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010471_0_0_11"/>
    <dbReference type="OMA" id="RWEENRG"/>
    <dbReference type="OrthoDB" id="66124at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07430">
        <property type="entry name" value="GH15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019248">
        <property type="entry name" value="Glucodextran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015220">
        <property type="entry name" value="Glucodextranase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09985">
        <property type="entry name" value="Glucodextran_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09137">
        <property type="entry name" value="Glucodextran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981438" evidence="2">
        <location>
            <begin position="33"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="domain" description="Glucodextran_N" evidence="4">
        <location>
            <begin position="42"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="3">
        <location>
            <begin position="460"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Glucodextran_C" evidence="5">
        <location>
            <begin position="903"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1132" mass="115702" checksum="D1737647A9EB515C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q738</accession>
    <name>C7Q738_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795779.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7222"/>
    <dbReference type="EnsemblBacteria" id="ACU76051">
        <property type="protein sequence ID" value="ACU76051"/>
        <property type="gene ID" value="Caci_7222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7222"/>
    <dbReference type="eggNOG" id="COG1520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013864_2_0_11"/>
    <dbReference type="OMA" id="DAPGEWW"/>
    <dbReference type="OrthoDB" id="1177619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981444" evidence="1">
        <location>
            <begin position="40"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="839" mass="87100" checksum="93E0CB66823BF6AA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7V7</accession>
    <name>C7Q7V7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793853.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5265"/>
    <dbReference type="EnsemblBacteria" id="ACU74124">
        <property type="protein sequence ID" value="ACU74124"/>
        <property type="gene ID" value="Caci_5265"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5265"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_16_0_11"/>
    <dbReference type="OMA" id="LGNVQYF"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="546" mass="58642" checksum="35454B7A6A6D8FAB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q834</accession>
    <name>C7Q834_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ordered locus">Caci_5342</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793930.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5342"/>
    <dbReference type="EnsemblBacteria" id="ACU74201">
        <property type="protein sequence ID" value="ACU74201"/>
        <property type="gene ID" value="Caci_5342"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5342"/>
    <dbReference type="eggNOG" id="COG0192">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041802_1_1_11"/>
    <dbReference type="OMA" id="MPYLRPD"/>
    <dbReference type="OrthoDB" id="1024388at2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="128"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="248"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="260"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="43190" checksum="4E0BEB0D440F3EF0" modified="2009-10-13" version="1">MSGTVRRLFTSESVTEGHPDKIADQISDAILDSLLKDDPKSRVAVETLLTTGQVHIAGEVTTTAYADIPRLVRDTILNIGYDSSKKGFDGESCGVSVSIGSQSPDIAQGVDTAYESRVEGDTDELDRQGAGDQGLMFGYACTDTPELMPLPIALAHRLSHRLATVRKDGTVPYLRPDGKTQVTIEYDGHKAVRLDTVVLSTQHASDIDLDNLLTPDIREQVVMPEIDALELDTSDFRLLVNPTGRFEIGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERCEVQVAYAIGKAEPVGLFVETFGTGLVEDVKIQEALLQVFDLRPAAIIRDLDLLRPIYQQTAAYGHFGRDLPDFTWERTDRAEALKKAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H0</accession>
    <name>C7Q8H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7329"/>
    <dbReference type="EnsemblBacteria" id="ACU76158">
        <property type="protein sequence ID" value="ACU76158"/>
        <property type="gene ID" value="Caci_7329"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7329"/>
    <dbReference type="HOGENOM" id="CLU_2970983_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="58" mass="6399" checksum="1FF11F499D998843" modified="2009-10-13" version="1">MSQSPQDVPVHVTAEVRPPALRKLARACITLARLQLSEPPQDKAVKRPSVPEDTEANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L2</accession>
    <name>C7Q8L2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1354</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785571.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1354"/>
    <dbReference type="EnsemblBacteria" id="ACU70277">
        <property type="protein sequence ID" value="ACU70277"/>
        <property type="gene ID" value="Caci_1354"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1354"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_3_11"/>
    <dbReference type="OMA" id="TRQVFFN"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="123"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="41812" checksum="5F7803671C961F9F" modified="2009-10-13" version="1">MRRTVYTEDHEAFRAMLRDFIAKEVVPVYPEWERDGHPPREFYHRLGELGVFGIEVPEEYGGAGLSTFKYQAIVIEETTRAGVTFGTTTVHVGLILPYLLAYATEEQKARWLPKFQSGEMMTAIAMTEPGTGSDLAGIQTTAKLSEDGRHYVLNGAKTFITGGVLADMVLVVARTAPATPEDRRGGLSILCVDTKAAGYSVGRKLDKIGLKTSDTAELAFTDVPVPVEDLLGEPGKGFSYLTHNLPQERLAIAVGGYASASAALQFALDYVRERTVFGTSVASFQNTKFVLAECATEVEAAQCMVDRALELHEAGELSVADAAKVKLFCTEAAGRVIDKCLQLHGGYGYITEFPIARLYADTRVSRIYGGTSEVMKTIIAKSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8R7</accession>
    <name>C7Q8R7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="5" type="ordered locus">Caci_1409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785626.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1409"/>
    <dbReference type="EnsemblBacteria" id="ACU70332">
        <property type="protein sequence ID" value="ACU70332"/>
        <property type="gene ID" value="Caci_1409"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1409"/>
    <dbReference type="eggNOG" id="COG0691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108953_2_1_11"/>
    <dbReference type="OMA" id="WTNHSAR"/>
    <dbReference type="OrthoDB" id="1720952at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="161" mass="18445" checksum="3A6DCA806F2E8E0B" modified="2009-10-13" version="1">MPKEQGQKVIARNKKARHEYEIEATYEAGISLTGTEVKSLRAGRASLVDGYAVIKDAEVWLQGVHIAEYAEGTWTNHSPRRNRKLLLHRAEINKLIGKTKETGLTLIPLELYFKDGKVKVEIGLARGKKTYDKRQTLMERQNKREAERAMAAAFKRNNRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W1</accession>
    <name>C7Q8W1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785670.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1453"/>
    <dbReference type="EnsemblBacteria" id="ACU70376">
        <property type="protein sequence ID" value="ACU70376"/>
        <property type="gene ID" value="Caci_1453"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1453"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_2_11"/>
    <dbReference type="OMA" id="SFVVDFH"/>
    <dbReference type="OrthoDB" id="1875458at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="25639" checksum="08F95C7628E36F32" modified="2009-10-13" version="1">MAVTDEAIEKIKEMIIKGRLRPGDRLPKEADLAAELGLSRSSLREAVRALSLIHVLDVRQGDGTYVTSLEPARLLEAMSFVVDFHRDDTVLEFLEVRRILEPAATAMAAQRVTDEEVAELREHLALIGNAPTVEDLVRNDLEFHSRIAACSRNVVLGSLLDSLSGPTTRARVWRGLTQEGALTRTLMEHTAILDALAERDSEGARAWATIHIVSIEQWLRNTLSEKRSTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z8</accession>
    <name>C7Q8Z8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787611.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3412"/>
    <dbReference type="EnsemblBacteria" id="ACU72318">
        <property type="protein sequence ID" value="ACU72318"/>
        <property type="gene ID" value="Caci_3412"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3412"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_11"/>
    <dbReference type="OMA" id="FIDYLAH"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20755" checksum="8F3898E5302084B9" modified="2009-10-13" version="1">MSTPLPAPSLHTARLRLRPFEDSDADDLFALQSNAEVLRYWDAPPWSERGRAEKFIAACRQMAQEGTGARLAVDRVSDGAFLGWCTLAGWNPVYRSASLGYCYDAAAWGHGYATEAARALLRWAFDTLDLNRVQAETDTRNAASARVLEKLGFVREGTLREDCVVNCEVSDSWVYGLLQREWRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q996</accession>
    <name>C7Q996_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793971.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5383"/>
    <dbReference type="EnsemblBacteria" id="ACU74242">
        <property type="protein sequence ID" value="ACU74242"/>
        <property type="gene ID" value="Caci_5383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5383"/>
    <dbReference type="eggNOG" id="ENOG5032Z5X">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288435_0_0_11"/>
    <dbReference type="OrthoDB" id="1994866at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="21693" checksum="B87A12CBE918AF68" modified="2009-10-13" version="1">MPQDLPHDYAPLPDLIGSVGGIESITLDGRRYYFGFDYRSDLVLSPLIDDPASMAVFASEYLRQSTGEHDVAYWAELVALGAAESSLTGDDASRTFTSQDLRGGLPEPGSHLLYLLGAATAWEVSFEEAPEAGQACVELGFDDDTEFFEPCLRAVQEHGIQARPAEWAVVSFYLTAAVRHAPANWGILFAPVAEAVTRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E3</accession>
    <name>C7Q9E3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ordered locus">Caci_5430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794018.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5430"/>
    <dbReference type="EnsemblBacteria" id="ACU74289">
        <property type="protein sequence ID" value="ACU74289"/>
        <property type="gene ID" value="Caci_5430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5430"/>
    <dbReference type="eggNOG" id="COG0061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008831_0_0_11"/>
    <dbReference type="OMA" id="VNLGHVG"/>
    <dbReference type="OrthoDB" id="1463423at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="188"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32123" checksum="888266FF76831562" modified="2009-10-13" version="1">MGHGERDVLLVVHTGRQVALDAARDTVARLSASGVGVRVLAGEAGELETDAPVCALDAGALEDIELVVVLGGDGTMLRGAEVARSAGVPLLGVNLGRVGFLAEAEYEDLAFVVDRIVARDYTVEERMTVDVEVSLDGQVVDRSWALNEASVEKASRERMLEVLVSIDGRPLSKWGCDGVIFATPTGSTAYNFSAGGPIVWPDLDALLLVPISAHALFARPLVVSPHSLLALELQPNGEDPGSKGAVMWCDGRRVLDLPHGARVEVRRGALPVRFARLHRAPFSDRLVAKFALPVDGWRAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9H7</accession>
    <name>C7Q9H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dual specificity protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5464"/>
    <dbReference type="EnsemblBacteria" id="ACU74323">
        <property type="protein sequence ID" value="ACU74323"/>
        <property type="gene ID" value="Caci_5464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5464"/>
    <dbReference type="eggNOG" id="COG2453">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1585601_0_0_11"/>
    <dbReference type="OMA" id="PGLWMGG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="90"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="18819" checksum="1AE89975213CDECE" modified="2009-10-13" version="1">MRTTGRGRDHGDWDDVPREPWSEVAPRLWMGGHEYIAGDGEWTTAVVADQFDVVYSLHFREGYGPGTGVDHHVLEVPDDVLTARQIFAVEKFAASAALDYAAGRRVLVRCRAGMNRSGLVVAEVLIRCGYTAPDAIAMIRRRRAAGALSNLSFVAYLETGLGLAAELSALGTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I5</accession>
    <name>C7Q9I5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794060.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5472"/>
    <dbReference type="EnsemblBacteria" id="ACU74331">
        <property type="protein sequence ID" value="ACU74331"/>
        <property type="gene ID" value="Caci_5472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5472"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="CNIGYAH"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="29"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="3">
        <location>
            <begin position="108"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="994" mass="105443" checksum="8A64FA62EB19785E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9M6</accession>
    <name>C7Q9M6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7368</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7368"/>
    <dbReference type="EnsemblBacteria" id="ACU76195">
        <property type="protein sequence ID" value="ACU76195"/>
        <property type="gene ID" value="Caci_7368"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7368"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033532_0_1_11"/>
    <dbReference type="OMA" id="WFPEAGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="211"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="41680" checksum="8241F3409037B64D" modified="2009-10-13" version="1">MVAKHYAAIFKAPGSKGFSSAAFVGRLPISMLGLGTILMIKESTGKYALAGVVAGTMALVQAFFGPFLARLIDRRGQAEIGFPSLAVSTTALISLMLCVRFDEPTWTWFASAALAGAFQPNVGALVRARWTKLYTGTPSLHTAYSFEAVMDEVVFMIGPILVTFLTLQVHHEAGVGLATGFLAVGTTAFLIQRRSQPVPHPPEHHTGPAAIAIPGMRVVLACAIAIGVMFGSMEVVTVAFAEEHGHSDWAGLLLAVYAGGSFVAGLIFGATHWETPLYRRIQILLAAVLVTAAPMTLAPNIGVLALVLLLAGFAISPTLITLVALVEYLVPAARLTEGMVIETTGAAVGITAGSAVSGWLIDRSGAHTAYLVPVAGSALALLTALLGSRWLRPGDPAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA26</accession>
    <name>C7QA26_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1503"/>
    <dbReference type="EnsemblBacteria" id="ACU70424">
        <property type="protein sequence ID" value="ACU70424"/>
        <property type="gene ID" value="Caci_1503"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1503"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_4_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="36"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20488" checksum="32C293BA456C8DA9" modified="2009-10-13" version="1">MVASGYAYSLLHADLPVCIGYQAVGRSVSTRHCVLPARAESVSAARRFVRDVAEDWRGQSDRFGTLLENLGIVVSELVTNALVHAYEAVMPGRVCEESDLISLCLVHEPCDTGAGEAGVERVLFAVADPSAASPVAPTPARAADGLWGLDESGRGMYLVEALADDWGWRRFRAPGAAEPSGKVVWALFELAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG3</accession>
    <name>C7QAG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin HHE cation binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792191.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3557"/>
    <dbReference type="EnsemblBacteria" id="ACU72462">
        <property type="protein sequence ID" value="ACU72462"/>
        <property type="gene ID" value="Caci_3557"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3557"/>
    <dbReference type="eggNOG" id="COG3945">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095990_1_0_11"/>
    <dbReference type="OMA" id="HEERVGM"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="219" mass="24406" checksum="9FEE1E9993C98891" modified="2009-10-13" version="1">MTNNALPGTGAAKYGPGDRLIAMQAAHDAFRRDLERMARAASPANLRDPKRRQSILNGWAVFENQLLIHHKHEDRFLWPRLRQRLAGSSAAQSTLDAMDAEHALIDPLLEAVNHSFAHGGEGAGAVIEEMTDKLGGHLEHEEREAMPMIGEALSDAEWKAVVSDIRKATKLSSAAQFMPWLSEGVDAEGEKTILSIMPPPARVVYRRIWKPKYTNVERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAX3</accession>
    <name>C7QAX3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5587"/>
    <dbReference type="EnsemblBacteria" id="ACU74446">
        <property type="protein sequence ID" value="ACU74446"/>
        <property type="gene ID" value="Caci_5587"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5587"/>
    <dbReference type="eggNOG" id="COG4886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054192_0_0_11"/>
    <dbReference type="OMA" id="ISWIQQS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="34396" checksum="4AFECEF3F07FAB49" modified="2009-10-13" version="1">MIQDFRHDALTVFHGLPVFAFVHGEAAQLEPHGVPEDIESWAWRVGAAEYDGPDGEGIWALFLATVDTSRVRALTLGAWDSEMSGEGWPDYCGALIDAADRFPNLEALFVGDLPSEMSEVSWIEQADPAPLLAAFPNLVEFGMRGTSGLQIEPLVHDRLRELTIQTGGLPPQIVRAVGASKLPALTGLDLYLGTRIYDGGATAEDLAEILSGAAFPALRHLGLRNAEDTDALAAALAHAPVVARLESLDLALGMLGDDGAAALLAGQPLTHLRRLDLHHHWLSEAMIERLWQALPDVDVDVDEALLERDRDRFIAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB44</accession>
    <name>C7QB44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76335">
        <property type="protein sequence ID" value="ACU76335"/>
        <property type="gene ID" value="Caci_7510"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7510"/>
    <dbReference type="HOGENOM" id="CLU_2877531_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982978" evidence="1">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="6614" checksum="E1F76F1FF325696C" modified="2009-10-13" version="1" precursor="true">MVVIFMAVAGCVAVALLGRAAATSAQRMRSWYRGSVEGSKTELVVLAAVVGGLLGELYLRMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBJ3</accession>
    <name>C7QBJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1649</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785864.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1649"/>
    <dbReference type="EnsemblBacteria" id="ACU70570">
        <property type="protein sequence ID" value="ACU70570"/>
        <property type="gene ID" value="Caci_1649"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1649"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008359_0_1_11"/>
    <dbReference type="OMA" id="CARIRTH"/>
    <dbReference type="OrthoDB" id="1043186at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="669"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="507"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="865"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="914" mass="97376" checksum="4B47D22907CED31D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBW9</accession>
    <name>C7QBW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792317.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3686"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72588">
        <property type="protein sequence ID" value="ACU72588"/>
        <property type="gene ID" value="Caci_3686"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3686"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_0_11"/>
    <dbReference type="OMA" id="QTFARRF"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="29"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="35277" checksum="36D726F8FFD025E5" modified="2009-10-13" version="1">MSRRAFRDAESEGDLADVRDAPLSRMTVDIAIPVYNEERALPGCIETLWTYLSERFPFAWEITIVDNGSTDGTLLAAEGLASAWPYVSVLHQDRKGKGLAVRTAWLASTADVVAYMDVDLSTGLDALLPMVASLVNGHADIAVGSRLASGARVIRGVKRDITSRGYNALLRLVHGVRFTDAQCGFKAARAEVVVPLLRRVRDNGWFFDTELLLLAELNGLRLHEVAVDWVDDVASQVAIPRVASGNLRGMLRLARLRLLGAATVSGLPQRPAPTATHPDAVLGQARRVTSRRRYASRAPVHLAGAAALVAYVITRFVVAGPGRRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY1</accession>
    <name>C7QBY1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792329.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3698"/>
    <dbReference type="EnsemblBacteria" id="ACU72600">
        <property type="protein sequence ID" value="ACU72600"/>
        <property type="gene ID" value="Caci_3698"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3698"/>
    <dbReference type="eggNOG" id="COG1473">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023257_6_0_11"/>
    <dbReference type="OMA" id="MKMHACG"/>
    <dbReference type="OrthoDB" id="796259at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="204"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="44997" checksum="27037991866DEF65" modified="2009-10-13" version="1">MRDLPKSLSGSFLTEPFSAAQAVELYLHLHRDPELSGAEERTAARLARALTGDGFEVASGVGGHGVVGVLRNGSGPTVMLRAELDALPVREQTALPYASTATALDAEGRLVPVMHACGHDLHVACAAGAATVLAQRRDRWRGTLMVVGQPAEETLTGAAAMLEDGLYERFAPGPPDAVLAQHSAPLPAGMTAHPTGAATAAGAALRVVVHGRGGHAATPHLAIDPVRVAAAIVLRLATVADEELGTAAPAAVSVGSLHAGTSPNVIPDEAHIEATIRTLTDPHLERLLAAVHRIIAAESEAAGCPEPPAVTLLSRTPANHPDPTLAAAIIRAHRHLLGTERVALWPPTLATEDFPLFGPPGAATGLHKSPATRTAYWMFGTIGPTQWHQTPGHTAAEKLATLAPNHSPKYQPDPGPAIPAGIRTLASAALAAGLAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC78</accession>
    <name>C7QC78_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5667"/>
    <dbReference type="EnsemblBacteria" id="ACU74526">
        <property type="protein sequence ID" value="ACU74526"/>
        <property type="gene ID" value="Caci_5667"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5667"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030803_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="584" mass="61858" checksum="5723922C2FE6CCAD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCX7</accession>
    <name>C7QCX7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sucraseferredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785981.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1766"/>
    <dbReference type="EnsemblBacteria" id="ACU70687">
        <property type="protein sequence ID" value="ACU70687"/>
        <property type="gene ID" value="Caci_1766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1766"/>
    <dbReference type="eggNOG" id="COG4759">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050357_1_0_11"/>
    <dbReference type="OMA" id="RDRCCAL"/>
    <dbReference type="OrthoDB" id="1095432at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010350">
        <property type="entry name" value="Aim32/Apd1-like_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030108">
        <property type="entry name" value="Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902">
        <property type="entry name" value="PTHR31902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31902:SF10">
        <property type="entry name" value="PTHR31902:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035042">
        <property type="entry name" value="UCP035042_thirdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="35489" checksum="DC5D1FB1EB39B028" modified="2009-10-13" version="1">MRDDQLPSPQPHACSVLSRELDEPLAGTGAVAGAWLLAEQPGPWGRTAVTASRLDPALGAELEGRTAGTAVRLALIRRVEDHHDHEPPHRRWYAASTHPRRTWLATGVVAYPTDLLKIDFAALGAGDRRAVAGLEHEFVDAPLLGVCTNGKRDACCATLGRRVAVAVEAAEEAAEALDVVAAPEAEQEIPAVWEITHLGGHRFAPTAVVLPSGYSYGRLDAASATRVLADARQGRMAVRGCRGRSTWSRAGQVAELAVRSALDEAAESALDVVAVTQTAPDPEPAWTAVVEHEDGRAYEVSVRGAYAPVPRPESCGKADGTPLELRVDAVDKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDS5</accession>
    <name>C7QDS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794428.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5841"/>
    <dbReference type="EnsemblBacteria" id="ACU74699">
        <property type="protein sequence ID" value="ACU74699"/>
        <property type="gene ID" value="Caci_5841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5841"/>
    <dbReference type="eggNOG" id="COG5446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090632_0_0_11"/>
    <dbReference type="OMA" id="VPYLKYP"/>
    <dbReference type="OrthoDB" id="2061199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012666">
        <property type="entry name" value="CbtA_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09490">
        <property type="entry name" value="CbtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="29941" checksum="62F61306D248DB3D" modified="2009-10-13" version="1" precursor="true">MERRLITRGLVAGALAGLVAFCFSRIFAEPAITKAIAYESGRDAAQAALNRAAGLPVEAAGPDLFSRTVQSNLGIGVGLIGFGAAMGAIYAVVYLLCLGRVGKIQPKVLALLVAGAGLAGIYLVPYLKYPANPPAIGHPETIKPRTGLYLTMVICSVAFMLAAIWLGRRLAPRFGNWNASLLGALGFAVAIGIVMVILPSLGELSANVHLSGHHATETPLPLADAKGNIVYPGFPADALFSFRFYSICNQVILWGALALVFGPLAERVLRPAMQPAEAAGGAGVAPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEA0</accession>
    <name>C7QEA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin dehydrogenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786085.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1871"/>
    <dbReference type="EnsemblBacteria" id="ACU70791">
        <property type="protein sequence ID" value="ACU70791"/>
        <property type="gene ID" value="Caci_1871"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1871"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_3_1_11"/>
    <dbReference type="OMA" id="PLTYHRP"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30413" checksum="E19836B1C68A3260" modified="2009-10-13" version="1">MKPPPVVYHGPDTVDEAVRLLAEHGAHAKVLAGGQSLVPMLNMRLTAPSRLIDVNRLDELAYVRTDLEGVRVGALARHADVERATHAFEAVPLLRQAVRTVAHPTIRNRGTTVGSLVHADPCAEMPAVLALLDGELLLRSERGGERVVKAADFFVGPMESACQEDELAVEAYFPKPKGRTGTDWREMSRRNGDYALCGVGTSVRVTEAGEVTSAKAVFIAMGPMPRVVDVTAAGADWDAAAEIAVEQLEPEDDIHASAEYRKHLARILTARSLRASYEAVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFH8</accession>
    <name>C7QFH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796480.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7932"/>
    <dbReference type="EnsemblBacteria" id="ACU76755">
        <property type="protein sequence ID" value="ACU76755"/>
        <property type="gene ID" value="Caci_7932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7932"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_0_1_11"/>
    <dbReference type="OMA" id="GCDGWLE"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="38863" checksum="866093705FBD1CF7" modified="2009-10-13" version="1">MSSSPDRKRPGRTSKPTIAVTGAAARLGEALTGKLAFGGEVRRVVGLDAERGAAPATWRLGEVTDPQLAERLSGVDTLVHLAVDADLNSEPRERTARNVRAAQTAITAAAAAGVHHVVLLSTAMVYGALPDNPLPLEDDAPLRATPDGTLVGDLLEIERLAAIAPRAHPGLDVTVLRPAAIVGPGVDTYLTRHFEAPRLLVVRGSKPVWQFCHIDDLLSALEYAALGKVSGVVPVASDGWLTQDEVEEISGMRRMELPEGLAVGAAERLHRLHLTPAPASDLQYVMHPWAVSNKKLREAGWEPAFTNEEAFGQLLEDIDGHHAALARRLGKKDAAAGLGAAGATVALVGTAALVRRARRKRRGGGSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFI7</accession>
    <name>C7QFI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7941"/>
    <dbReference type="EnsemblBacteria" id="ACU76764">
        <property type="protein sequence ID" value="ACU76764"/>
        <property type="gene ID" value="Caci_7941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7941"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_1_0_11"/>
    <dbReference type="OMA" id="RIAINQC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="97"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="195"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29409" checksum="0C3084975499E8BB" modified="2009-10-13" version="1">MVMSAVLEIGGGDVVADANSARNPGAVPVNTIGPRIDLGELRRRRAARKAALEKNRRGAEAIPDTAMPAEAAQSVGETQPLDAAAVGWEPPSWDDIVRTHSQRVYRLAYRLTGNQHDAEDLTQEVFIRVFRSLSSYQPGTFEGWLHRITTNLFLDMVRRRARIRFDSLGEDADDRLPGREPSPERIFVDSHMDADIEAALAALAPEFRAAVVLCDIEGLSYEEIAATLDVKLGTVRSRIHRGRSQLRAALEHRAPGAAANASGKEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFS0</accession>
    <name>C7QFS0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD-superfamily subfamily IB hydrolase, TIGR01490</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784304.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0054"/>
    <dbReference type="EnsemblBacteria" id="ACU69009">
        <property type="protein sequence ID" value="ACU69009"/>
        <property type="gene ID" value="Caci_0054"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0054"/>
    <dbReference type="eggNOG" id="COG0560">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052657_1_0_11"/>
    <dbReference type="OMA" id="DHDQMER"/>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30399" checksum="668DE4EF499AFF95" modified="2009-10-13" version="1">MDEHADARADGAGRPAAFFDLDKTIIAKSSTLAFGRSFYNGGLINRRTVLRTAYAQFVYLAGGADHDQMERMRQFLSAMATGWDVEQVKEIVAETLHDLIDPLIYSEAAALIAEHKAAGRDVVIVSTSGSEVVEPIAEMLGADLAIGTRMAVGEDGKYSGEIEFYAYAENKAKAIVELAAERGYDLTRSFAYSDSATDVPMLESVGHPYAVNPDRTLRKEATAREWPILVFDKPVALRSRVGELAAKPAVSGTALGLALATAGTIWWLGTRGRRRRGSGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG50</accession>
    <name>C7QG50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4027"/>
    <dbReference type="EnsemblBacteria" id="ACU72895">
        <property type="protein sequence ID" value="ACU72895"/>
        <property type="gene ID" value="Caci_4027"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4027"/>
    <dbReference type="HOGENOM" id="CLU_1313576_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983111" evidence="2">
        <location>
            <begin position="30"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="20919" checksum="A7022AF340D0C4F8" modified="2009-10-13" version="1" precursor="true">MARHHFGCRVAVGFAVGAALLTAAGCASGASKSSSASSGTAPSSAGSQPATASAPGSTGSSTPTASASVDQSSPQAQAAIATYKALWADVVKVEATMNDQDPTLANHLTGGALSFFQQAIHINKLDGYVAKGEPKLLHPTAKQIIGSGAAAKVLVEDCVDDSGFNLYTSDGTFVHNGHPGGRRLTQALVERSDGVLKASAFAFSAPGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG83</accession>
    <name>C7QG83_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792657.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4063"/>
    <dbReference type="EnsemblBacteria" id="ACU72928">
        <property type="protein sequence ID" value="ACU72928"/>
        <property type="gene ID" value="Caci_4063"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4063"/>
    <dbReference type="HOGENOM" id="CLU_1783392_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15536" checksum="2F51DF123B9E2AF0" modified="2009-10-13" version="1">MTIDHLMTAEQLLNLSKETFEEAKDKAVYVAALTTAESRGGSWPDFRGDLDQTDAAEAVAWIAGQAAAKGAFGYHLDLIATISDAPGQLTAGFQLTRVDEPTLNTGQVPLKDLYLPGTVGAHAAWEVICRIKHHLTAAESRDTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG3</accession>
    <name>C7QGG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aminodeoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792737.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4144"/>
    <dbReference type="EnsemblBacteria" id="ACU73008">
        <property type="protein sequence ID" value="ACU73008"/>
        <property type="gene ID" value="Caci_4144"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4144"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025574_4_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="409" mass="43072" checksum="163D658A37A7BCF0" modified="2009-10-13" version="1">MRDEEPGGLGGFADEVSRMLHARALLHQEHTDPVGITRRNLKMAKQRRRAVLGTTTTLAVTGGAVFGVYALSGHAQDNGGTRSVGQNVAADYTGAATCPATAKVPVDVPRGATTTQIANALFTAGVVASPQAYVDAADRNQGSVGITAGTYAICPQISGANAVLELSKKSNLSDASQIIVTSHEWSKDVIASLVDKRKWKQADFDAAIASNTIGLPAWSVDSTSHKFTAEGMLEPGTYSITSSDTPQSILSQMVAKRMTYFKSIDFENKAASLVCGAAKCTPEQVLTIASIAEGEVAEPGDGARVAEGVYARLKAGDYLAVDSTALYAIGHLPAGQLPSAKQVQDPNNPYSTYAPHHGLPPTPVYITSDDMIKSALAPTHDGTYYWCVTSTGARFFTKGQETQRDQGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK9</accession>
    <name>C7QGK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Precorrin-8X methylmutase CbiC/CobH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobH/CbiC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794618.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6032"/>
    <dbReference type="EnsemblBacteria" id="ACU74889">
        <property type="protein sequence ID" value="ACU74889"/>
        <property type="gene ID" value="Caci_6032"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6032"/>
    <dbReference type="eggNOG" id="COG2082">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084703_0_0_11"/>
    <dbReference type="OMA" id="DLAWQAY"/>
    <dbReference type="OrthoDB" id="1812068at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016993">
        <property type="term" value="F:precorrin-8X methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003722">
        <property type="entry name" value="Cbl_synth_CobH/CbiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036588">
        <property type="entry name" value="CobH/CbiC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02570">
        <property type="entry name" value="CbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63965">
        <property type="entry name" value="SSF63965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiC" evidence="5">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="21170" checksum="23291AFC72BC11EB" modified="2009-10-13" version="1">MSARAVHPIEAESYRILRARLDTSELPPHTKAVLERVIHASADFDYATDLVTDEAALAHAAAALRAGAPIVADVEMVAAGITRRDAVCAIKDPAAPKLAADLGITRSAAALRIAAEQAGPGAVYVIGCAPTALFELIAIAEQARPALVIGLPVGFVGAAESKAALRESGLPAVSNVSGKGGSAVAAAALNALIYEDLIHKAPAKEGTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV0</accession>
    <name>C7QGV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796525.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7977"/>
    <dbReference type="EnsemblBacteria" id="ACU76800">
        <property type="protein sequence ID" value="ACU76800"/>
        <property type="gene ID" value="Caci_7977"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7977"/>
    <dbReference type="HOGENOM" id="CLU_152435_1_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021385">
        <property type="entry name" value="DUF3017"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11222">
        <property type="entry name" value="DUF3017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="102" mass="10742" checksum="9B0B5ECA045F5AC1" modified="2009-10-13" version="1">MAVNNRPPGASFGRSVVAEWPILAVLAAFGFGMTVILHDEVFQGAAVMGMSLLLAAGLRLFLPTRVVGTLAVRRRAIDVSTYTIVGTTLVVLGLLVQGIFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGY3</accession>
    <name>C7QGY3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCP-like extracellular</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76833">
        <property type="protein sequence ID" value="ACU76833"/>
        <property type="gene ID" value="Caci_8010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8010"/>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048111_2_2_11"/>
    <dbReference type="OMA" id="GSPWAMM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="116"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="23735" checksum="5270CD495599E7BD" modified="2009-10-13" version="1">MVAGLAITAPLMTLRAHDEDTVALGPDTPNSSVPTSAGPPSAATPPNAAAKAPALVPSPDPAATTGSRSLPPVSRDATRTPTSALPTRTASTAGSGAPTVQISSDEATSYEAEVVALTNDQRAAHGCPALRDDSRLRAAAVGHSVDMQARDYFDHNTPDGVTPWTRIGAQGYSDPSAENIAKGQPTPQAVVEAWMNSAGHRANILNCSSKAIGVGVQFGPGGPWWTQDFGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIA0</accession>
    <name>C7QIA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6123"/>
    <dbReference type="EnsemblBacteria" id="ACU74977">
        <property type="protein sequence ID" value="ACU74977"/>
        <property type="gene ID" value="Caci_6123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6123"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_1_11"/>
    <dbReference type="OMA" id="CQGALHG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="23570" checksum="8385641750D4A145" modified="2009-10-13" version="1">MNGSAKADTGAGRVAGQSAPAVVSPAAVVPPSAIAPPVVALPPSAAERPLRADARRNRQRVLEAAAQAFAADGPAVPLDEIARRAGVGAGTVYRHFPTKEELLAAVLIARMETMLAEVRGALAKPDPGPAFYASFVAMTLDARDKTDLAEALTSHGIDVRAATGEIAGALKAALADLLRRAQDAGAVRADVGVEDLHALVIGAIAAARSAPLADVPRVAGLVADGLRPRPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB9</accession>
    <name>C7QIB9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794725.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6142"/>
    <dbReference type="EnsemblBacteria" id="ACU74996">
        <property type="protein sequence ID" value="ACU74996"/>
        <property type="gene ID" value="Caci_6142"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6142"/>
    <dbReference type="eggNOG" id="COG2074">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092760_1_0_11"/>
    <dbReference type="OMA" id="MVRKEAM"/>
    <dbReference type="OrthoDB" id="1383055at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="219" mass="24276" checksum="5E9B15D98E533216" modified="2009-10-13" version="1">MPEQTWNPFETLSRTLWIGGAQWAGKSTVARILAHRHGLTAYHYDYHDARGHQDRRIARRVALGEPPENPTPDTVWVGTTPEAMAAATLDGFPVRFEWALDDLRGLYSPRPIIAEGWGLRPELVAPLLDTPRRMIVLVPTENFRQHQLSTLPRAAAMGQSTSDPARAQANRIARDRLVAEDAVRKAEEHGIRVIEVDGSRDAAAIADEVGEHFGEALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIH0</accession>
    <name>C7QIH0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794776.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6193"/>
    <dbReference type="EnsemblBacteria" id="ACU75047">
        <property type="protein sequence ID" value="ACU75047"/>
        <property type="gene ID" value="Caci_6193"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6193"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602299_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="481" mass="51992" checksum="28B37298F39A8F6A" modified="2009-10-13" version="1">MNRVDDRGRPPGQQPHEPHPTHQSYQPHQPPRAPQPFRPPPVPSHPTIDDYERAVAAFRQTPNPAAEFAYLREVALVGARLGTIRPADIVRHVQPAAVAVTLVMEPEIVTVGDAVARAILRGDSAGPQYWARMVREVDTARGTLAALVKARPDSGRGVIARGIRRTPAEQGAGADMSGQRWRAANVVLALAPPLAARAFLASSATMHKQPSEAELSALREQASLILDMASQAPLCRELVGHAFGSLGDTALRMRLAENPFTPDSVLARLVAEHDTEPEVTRAVQVHEFAGGTARRLAFQAVRDEPEEVLRGLREMLRLCGEEPFLEMLQAAPEEEAAWVRSVIAAAGPDLQPETRLRAYVRLAEISAPEVVWAVELTRAGGLERMMPEVRASMAAGSAEPMIAAVHDDKAAAAARRGAARLTGRGGAVVRSGRAPHPGSEQAEEWNRHSSARAQAERHRAAAAEMKRWRSEGALDDPVPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII0</accession>
    <name>C7QII0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794786.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6203"/>
    <dbReference type="EnsemblBacteria" id="ACU75057">
        <property type="protein sequence ID" value="ACU75057"/>
        <property type="gene ID" value="Caci_6203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6203"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054109_0_0_11"/>
    <dbReference type="OMA" id="CVRMYTH"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041496">
        <property type="entry name" value="YitH_GNAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18014">
        <property type="entry name" value="Acetyltransf_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="30971" checksum="E17073B5710ABD8E" modified="2009-10-13" version="1">MTDRQQTMQITRASLADWPLIQGWCADEGWNPGDHDGPCFLAQDPEGFFVGRVDGEPVSAVSVVHYGDAFAFLGLHLVRPEFRGRGHGLATWKAALPRAGARTVGLDSTAAQQDIYRKSGFDDAYRTVRYVGDLASDGSGPAAAVPLARAGFAEIADYDALCFPAPRPVFLREWFAAPGHVGRALIVDGRLVGYGVLRPAHDGYRVGPLFADSRVYAEVILDALVAGAVGDGGEGGRRIVIDVPDTNPEALAMVGALGLEPSFEMARMYTGPVRDVDHSKVFGTTTLELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM9</accession>
    <name>C7QIM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796654.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8106"/>
    <dbReference type="EnsemblBacteria" id="ACU76929">
        <property type="protein sequence ID" value="ACU76929"/>
        <property type="gene ID" value="Caci_8106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8106"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_542581_0_0_11"/>
    <dbReference type="OMA" id="FQQAMGI"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="41"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="502" mass="52967" checksum="9BE492988A192CF1" modified="2009-10-13" version="1">MSEVLGAQHPDAAAADGARRGTAIGSPGPLRPIFSGSYQKLWLLLLFGWLVSYADRTVTGPVVAWMIHDKGGFIGDSAHPAALGGLIGSMFFTGYMLTQYAGGRLGDRFGHREMLVLSLLWAGVLTLVSGLATGLVVFVVARVLTGLGEGVFYSNDRVLVITHTPPRRRTIGLGVAVSGLSIGLTVAIVATPYMIDWGTSAGFGARAWSMPLFLFGTFSLLVGVATWLFFRARGDRPLRLGAPLLRLIGYSVPCAAAITVLYLVSDKAGWTAWETAIGSGVLALVMIGFVVRDLKRTGKAETLLTKDLWLLYIAFIAVMWNLWFFSFWSVEIVAETAHSSLTSAALTAAFNAGAGIIGFPVGGWLADRRVRQGKGRKSLAIICAVAHTLLAVAFGVSLAVGHPSLLLLGLILFTSGLFFNALQPIVHGILGDQVPDADRGAVFGVFNLIAEIGAVASPVVSGVLRDSTGSWAPGVFTAAGIMAVSVPLYALVRERIPGAART</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIR7</accession>
    <name>C7QIR7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76967">
        <property type="protein sequence ID" value="ACU76967"/>
        <property type="gene ID" value="Caci_8144"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8144"/>
    <dbReference type="HOGENOM" id="CLU_2407869_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9961" checksum="13A2B4C6DBCFCF76" modified="2009-10-13" version="1">MGWVQTLVNSPGRDNGDPSYGSFGDPGGDGGFQVVIVPDDISALDAEVRAYRREVARAKARAKAWSVLTWPLRALSGLGRRVGRALGFLVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIT5</accession>
    <name>C7QIT5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796710.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8162"/>
    <dbReference type="EnsemblBacteria" id="ACU76985">
        <property type="protein sequence ID" value="ACU76985"/>
        <property type="gene ID" value="Caci_8162"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8162"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="TPRIMRA"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="27839" checksum="088C6A62047D8F75" modified="2009-10-13" version="1">MTRTDDTEVPDYRSLLSLDGKNFVVLGAGQGIGRQASHALAALGARVFCVDLDAGLADDIAKEVGGVPWAGDAIEQASAERLYQDAETALGRIDGIVDIIGMAKYAGLLETDRDSWEWHHGIVLQHAVNAIRFGAPRMIATGGGVLTVVASVSGMQSAPSHGAYGAYKAALMSLVRTAAVELGPKGLRVNAVAPGLVMTPRVAGYLSGAEKERGARNAPLRRSAFPKDIAEVILFLCTGLSSYITGQTIVVDGGVSAKFGYSLPGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIU2</accession>
    <name>C7QIU2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796717.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8169"/>
    <dbReference type="EnsemblBacteria" id="ACU76992">
        <property type="protein sequence ID" value="ACU76992"/>
        <property type="gene ID" value="Caci_8169"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8169"/>
    <dbReference type="eggNOG" id="COG0677">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_3_2_11"/>
    <dbReference type="OMA" id="MLINEGQ"/>
    <dbReference type="OrthoDB" id="295459at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="314"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="43521" checksum="64BE10F37862A71B" modified="2009-10-13" version="1">MDETTRHGFAHDVVVIGGGGHVGLPLAIALADRGSSVVVYDISAEAVAAVNEARLPFEEPGAGPVIAAVVADGRLRASTDPAVVAGCEHVIVVIGTPVDEHLNPDQTAIPRALETCAPHFRDGQLLMLRSTVYPGVTALVERMIARLGVDVDVAFCPERIAEGRAMTELFELPQIVSGRTERAQRRAEALFRRLTDKIVHLSPEEAELAKLFTNTWRYIKFAAVNQFYIMANDRGLDFERIRAGLAQDYPRAADMPGAGFAAGPCLFKDAMQLAAFHNNNFTLGYAAMTTNEGLPLYVADRLDAQYDLANMTVGILGMAFKGGSDDTRSSLSYKLKRILRFKAAEVLCTDPLVTTDPSLVGLDEVLEKADLLIVGAPHPEYRGLKASVPVADIWNVLGEGVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX1</accession>
    <name>C7QIX1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8198</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796746.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8198"/>
    <dbReference type="EnsemblBacteria" id="ACU77021">
        <property type="protein sequence ID" value="ACU77021"/>
        <property type="gene ID" value="Caci_8198"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8198"/>
    <dbReference type="eggNOG" id="COG3290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020211_11_1_11"/>
    <dbReference type="OMA" id="HYQNGWL"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033463">
        <property type="entry name" value="sCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17203">
        <property type="entry name" value="sCache_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982928" description="Histidine kinase" evidence="7">
        <location>
            <begin position="40"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="426"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="538" mass="56033" checksum="EADF5942540EC54F" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ36</accession>
    <name>C7QJ36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0225"/>
    <dbReference type="EnsemblBacteria" id="ACU69178">
        <property type="protein sequence ID" value="ACU69178"/>
        <property type="gene ID" value="Caci_0225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0225"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="792" mass="84568" checksum="AA8D665EFA03822E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJE7</accession>
    <name>C7QJE7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786463.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2252"/>
    <dbReference type="EnsemblBacteria" id="ACU71170">
        <property type="protein sequence ID" value="ACU71170"/>
        <property type="gene ID" value="Caci_2252"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2252"/>
    <dbReference type="eggNOG" id="COG2329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088918_0_0_11"/>
    <dbReference type="OMA" id="HARSSHI"/>
    <dbReference type="OrthoDB" id="1347413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="22741" checksum="428A4529B00271CE" modified="2009-10-13" version="1">MFVRSLYITCDPADVGPALDVIAKAVPGMMAEQSGFDGIGVFADRALGKILTGSWWETEQALKNSDEQLRDRRVDMLARFVSTITTVNLEAAAFTPPASATSGSFRLQRMMFEPAMAGGIVRAFEEVGLPGLQAVDGFQGASLLLDRAHNIAGVGTFFRDTEALAASRGPHAAIRKAAFEQMKGGVQMLALEEFDVVELDLPTSNPIPVPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM6</accession>
    <name>C7QJM6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside-diphosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786542.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2331"/>
    <dbReference type="EnsemblBacteria" id="ACU71249">
        <property type="protein sequence ID" value="ACU71249"/>
        <property type="gene ID" value="Caci_2331"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2331"/>
    <dbReference type="eggNOG" id="COG0105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_6_3_11"/>
    <dbReference type="OMA" id="ALWFGEQ"/>
    <dbReference type="OrthoDB" id="1752581at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="2">
        <location>
            <begin position="8"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18301" checksum="1AA5B4AE64D8F7F5" modified="2009-10-13" version="1">MTDTGAPAERTLVLLKPDAVARGTMGRVLTRFEDALLKVVGSKMVWMDADLTRKHYFDLEERFGAGVYNATATFMQSGPVLALVLEGIDAVKTVRKLVGSTYPNEAAPGTIRGDYAHQNKAYATANGIAVANLVHASGNIDEAKQEVALWFTDEELFEYSTVAEKFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJP4</accession>
    <name>C7QJP4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxS</name>
        <name evidence="6" type="ordered locus">Caci_2349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2349"/>
    <dbReference type="EnsemblBacteria" id="ACU71267">
        <property type="protein sequence ID" value="ACU71267"/>
        <property type="gene ID" value="Caci_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2349"/>
    <dbReference type="eggNOG" id="COG0214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055352_1_0_11"/>
    <dbReference type="OMA" id="RYANRGW"/>
    <dbReference type="OrthoDB" id="784095at2"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="5">
        <location>
            <begin position="16"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="32243" checksum="FCCA3A80DCF37C6D" modified="2009-10-13" version="1">MSVNENSAQAPELGTARVKRGMAEMLKGGVIMDVVTPEQAKIAEDAGAVAVMALERVPADIRKDGGVARMSDPDMVDGIIEAVSIPVMAKARIGHFVEAQVLQALGVDYIDESEVLTPADETHHIDKWAFTVPFVCGATNLGEALRRIAEGAAMIRSKGEAGTGNVVEATRHMRQLRADIRRLATLDESELFLAAKNHQAPYELVKEIAATGKLPVVLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGDPEKRAKAIVEATTHYDDADLIAKVSRNLGEAIVGINLDTLPAEQRYASRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKE3</accession>
    <name>C7QKE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6363"/>
    <dbReference type="EnsemblBacteria" id="ACU75217">
        <property type="protein sequence ID" value="ACU75217"/>
        <property type="gene ID" value="Caci_6363"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6363"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_3_11"/>
    <dbReference type="OMA" id="NRITWNN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="23683" checksum="A10DB38EBD50A402" modified="2009-10-13" version="1">MDGVSPRPAQPDIRRALIEAAATILAESGPDGLSTRQLAREVGVSTTAVYTYFGGMDDLVRAMVHEGFARLNRALTATGDSQDPVADVVRLGRVYRENALRHRHLYAVMFGGSALAGFSLTDEDRAHGLYTLDLLVAAIERCVVAGRFRSGDATLVAHELWMSIHGIVTLEIGGYLFEPYDADACFDAQVCTLLVGSGDGLERARQSIAMSGAEAAAKEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVY4</accession>
    <name>C7PVY4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2458"/>
    <dbReference type="EnsemblBacteria" id="ACU71376">
        <property type="protein sequence ID" value="ACU71376"/>
        <property type="gene ID" value="Caci_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2458"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_0_1_11"/>
    <dbReference type="OMA" id="HVPKTYE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="96"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="35106" checksum="2E91FD6CD7CD85DA" modified="2009-10-13" version="1">MNTPARRSQPSKSGGGRGSGSGGGARGSGGSRQAGAGSGGSRQPAPAGGRSPGKAGGRSGGSGGGGNASGANAAAGSGGRDWRDYDPFADANEEGIRLQKVLAQAGVGSRRVSEDLIAAGRVEVNGEIVRHQGMRVDPETAVIRVDGMRISTAEGIVHFAFNKPMGVVSAMDDPDRPNLGDYVRGRNERLFHIGRLDVDTEGLILLTNDGELAHRLAHPSYEIRKVYRAQVYGTVPKDLGRRLREGVDLEDGLARVDHFRLLDSVGRNALVEITIHEGRNRIVRRIMDAVGLPVRGLVRTKFGPISLGDQKPERMRPLNKEEVGAVYKSVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW34</accession>
    <name>C7PW34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4418</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793011.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4418"/>
    <dbReference type="EnsemblBacteria" id="ACU73282">
        <property type="protein sequence ID" value="ACU73282"/>
        <property type="gene ID" value="Caci_4418"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4418"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="WYPLTLG"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="91"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="32969" checksum="9ADA99A4DEB252FC" modified="2009-10-13" version="1" precursor="true">MRRGRPRNSTPPLRAKARRAPHLRRKSLTLTVLCAVMVVYTLLPLAWLAINATKSQQNLFDSFGLWFKGFGFFSNIGDTFSYQHDIFGRWLLNTLMYVVVGAGGATLLATLAGYGLAKFDFAGKKAVFAVVIGAVAVPATALAVPTFLMFSKMGLTDTPWAIIIPSLISPFGLYLMWTFSSEAVPAEIMESARMDGAGEFRTFFSVSLPLLAPGIVTVLLFNVVTTWNNYFLPLIMLKNQNWYPLTLGLSTWNDQAHTAGGEVVFNLVITGSLITIIPLIAAFLLLQRYWQSGLSAGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK4</accession>
    <name>C7PWK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6432"/>
    <dbReference type="EnsemblBacteria" id="ACU75284">
        <property type="protein sequence ID" value="ACU75284"/>
        <property type="gene ID" value="Caci_6432"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6432"/>
    <dbReference type="eggNOG" id="COG3118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_10_0_11"/>
    <dbReference type="OMA" id="NPCRMLT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="36"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="16789" checksum="0F1F1CB8D843CEEB" modified="2009-10-13" version="1">MSVEPKTVRCPHCGKNNRVPAAAEGHPRCGNCHQSLPWIVDAEDSTFTQVVDKASIPVVVDLWATWCGPCRMVSPALEQVAADLAGKIKLAKVDVDASPQLSQRFEVRAVPTLLVIDRGRVLARQAGARPAAELRAWVEEALAGGSAAESSAATGSAGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWV0</accession>
    <name>C7PWV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP oxidoreductase coenzyme F420-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796932.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8384"/>
    <dbReference type="EnsemblBacteria" id="ACU77207">
        <property type="protein sequence ID" value="ACU77207"/>
        <property type="gene ID" value="Caci_8384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8384"/>
    <dbReference type="eggNOG" id="COG5495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055635_0_0_11"/>
    <dbReference type="OMA" id="GEPEWIA"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018931">
        <property type="entry name" value="DUF2520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019665">
        <property type="entry name" value="OxRdtase/DH_put_Rossmann_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037108">
        <property type="entry name" value="TM1727-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10728">
        <property type="entry name" value="DUF2520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10727">
        <property type="entry name" value="Rossmann-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rossmann-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2520" evidence="2">
        <location>
            <begin position="141"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="30073" checksum="82B1F1D5501A4E38" modified="2009-10-13" version="1">MDSAESRLAVGVVGTGRVGSALGAALQRAGHRVVAASGVSEQSVRRADKLLPDVPLLPPQEVLAVADLALLTVPDDALPGLIEGLVATGSIKPGTILAHTSGRFGYTVLDAATRAGALPLALHPAMTFTGTEVDVARLAGCSFGVTAPDPLRPIAEALVVEMGGEPEWIEESARPLYHAALAYGSNYLVTLVAQAKDLLAAAGVREPGRMLGPLLGAALDNALRSGDLALTGPVARGDAGTVAAHLEVLAERDPQAARGYRALGRLTADRAMASGLLSAEKAESLLGVLNKEPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX51</accession>
    <name>C7PX51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784697.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0450"/>
    <dbReference type="EnsemblBacteria" id="ACU69402">
        <property type="protein sequence ID" value="ACU69402"/>
        <property type="gene ID" value="Caci_0450"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0450"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1591588_0_0_11"/>
    <dbReference type="OrthoDB" id="1242748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980422" evidence="2">
        <location>
            <begin position="32"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="16683" checksum="DC89DB77230BA73E" modified="2009-10-13" version="1" precursor="true">MSGTTDSPARVAALTVIIVTAWLHAGSSAMADTGATSGPALGGGDITVSTLMAPGSLVISVPLRQPALTSKLQPITVTDNRTEDPGWTVTVILTSHETAGLTWNPDLLSAAPGESVILGPKTGPRPSLQQPRTLASTQPGASLGTALLSAALYPSGSGAATFTLTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXB3</accession>
    <name>C7PXB3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0519"/>
    <dbReference type="EnsemblBacteria" id="ACU69464">
        <property type="protein sequence ID" value="ACU69464"/>
        <property type="gene ID" value="Caci_0519"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0519"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064679_0_0_11"/>
    <dbReference type="OMA" id="WEILREH"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="147"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="39479" checksum="3B1FF7275678FD31" modified="2009-10-13" version="1">MVAALRLWRCRDDHKTIEILLLRHQLTILQRRLAAAGRRLRPDWADRAIIALLLGLVPKARRAGPCLFVTPDTILRWHRDLLRRRWAKKSRPKNDRRATHQNIKTLIPRLARQNPAWGYRRIHGELAGLGIAIAASTVWEILKDAGVDPAPRRGSVTWASFLRSQAEGIIAADFFTADLLDGTKVYVLTIIEHASRRIRVLGSTLHPTGQWTAQMARNLVMDLDDAAATVKFLIRDRGTNFTEAFDTVLADAGIRTVLCNVQTPRMNAIMESWVGSVRRGLLSRTLIWNHEHLRQILHHYELRHNTHRPHMSLSAAAPLKPLPPNITDLDALRVRRTRRAGGVINEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY6</accession>
    <name>C7PXY6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Smr protein/MutS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793175.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73446">
        <property type="protein sequence ID" value="ACU73446"/>
        <property type="gene ID" value="Caci_4584"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4584"/>
    <dbReference type="eggNOG" id="COG2840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2467710_0_0_11"/>
    <dbReference type="OMA" id="DIFNKGH"/>
    <dbReference type="OrthoDB" id="1888882at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="1">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="81" mass="9327" checksum="733A0FBA62F43054" modified="2009-10-13" version="1">METLDLHGVFRDDRAIYRTVQQALFRCSATGVDVLEIIPGRGSGTLKRRVLAFLEQRQLKRLYTRVEEDPGNAGRILVHFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC7</accession>
    <name>C7PYC7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795146.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6571"/>
    <dbReference type="EnsemblBacteria" id="ACU75417">
        <property type="protein sequence ID" value="ACU75417"/>
        <property type="gene ID" value="Caci_6571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6571"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_0_0_11"/>
    <dbReference type="OMA" id="YERTGAM"/>
    <dbReference type="OrthoDB" id="1245649at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="3">
        <location>
            <begin position="791"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="756"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1077" mass="114203" checksum="42C660B3DFEEB156" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYX8</accession>
    <name>C7PYX8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WGR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784829.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0597"/>
    <dbReference type="EnsemblBacteria" id="ACU69534">
        <property type="protein sequence ID" value="ACU69534"/>
        <property type="gene ID" value="Caci_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0597"/>
    <dbReference type="eggNOG" id="COG3831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006807_1_1_11"/>
    <dbReference type="OMA" id="FENWRAT"/>
    <dbReference type="OrthoDB" id="878234at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025406">
        <property type="entry name" value="DUF4132"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13569">
        <property type="entry name" value="DUF4132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4132" evidence="1">
        <location>
            <begin position="815"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1086" mass="117582" checksum="3B00B589F1A5904D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYZ9</accession>
    <name>C7PYZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0619"/>
    <dbReference type="EnsemblBacteria" id="ACU69555">
        <property type="protein sequence ID" value="ACU69555"/>
        <property type="gene ID" value="Caci_0619"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0619"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_2_4_11"/>
    <dbReference type="OMA" id="CFGHGDP"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="25564" checksum="4E9B88A883D21223" modified="2009-10-13" version="1">MASQPAYQLTPQVWRIPAGPFDFVNSFAIVEDDGRVSLVDTGMPSSAGRIEAGLKAMGKSVQDVHRIVLTHAHGDHAGGAAKLKEATDADISISAIDAPFARGGYAPPRDGSTLGGKFLNLLGPKGNKFAKVIVGEEFADGDVLPVGGGLRVVHTPGHTPGHVALRHEADGVLITGDSIWNVRKMGWGVRAFCSDIKLNQKTADVLGELDYEIAAFTHGKHVTQNARETVRRFLKEAKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZD0</accession>
    <name>C7PZD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2671</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2671"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71587">
        <property type="protein sequence ID" value="ACU71587"/>
        <property type="gene ID" value="Caci_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2671"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024190_0_0_11"/>
    <dbReference type="OMA" id="EYGIAMW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="552" mass="57300" checksum="7DBE396D4FE9FD64" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q023</accession>
    <name>C7Q023_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795245.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6670"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75516">
        <property type="protein sequence ID" value="ACU75516"/>
        <property type="gene ID" value="Caci_6670"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6670"/>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_707419_0_0_11"/>
    <dbReference type="OMA" id="FAVHRQW"/>
    <dbReference type="OrthoDB" id="1165736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGDG_synth" evidence="6">
        <location>
            <begin position="91"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="5">
        <location>
            <begin position="227"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="362" mass="38158" checksum="AF690005842F8BF1" modified="2009-10-13" version="1">MPHALLLSGSLGQGHDVMAAACADSLHDRGWTTSTVDAMALLGRRSGAAGEAVFRRLLAIPGVYDAFHFSALRPGNRLALYTEKAAVARLAPRIKELLEREPADLVVSVFATAAGAVDALHREGRQVPPHMVFCTDVTPHRLWVHPSTDVFLVTSQAAAAGVRRYRPDAAIAVVPAPLRPAFYTPPTKQQARQEFGVPDDARCVLLMSGAWGLGPVAAAAAALGAAGVHVLAVAGRNQELEARLRAVARREPRVHAFGYSDRVPSLMTAADLVVTSSGDTCSEARAIGRRLLLLDVVPGHGRDNLQHELELGHADVTGAAPRDVVRAALAALERPTPDPSIGSVRAPWEAAFGTALSSVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q034</accession>
    <name>C7Q034_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795256.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75527">
        <property type="protein sequence ID" value="ACU75527"/>
        <property type="gene ID" value="Caci_6681"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6681"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="AYDCIDV"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="38432" checksum="3D1CDE498E1996E4" modified="2009-10-13" version="1">MQYIKLGTTGLDVSPIAIGAMSYGEPDRGHPVWSKGEQEARPLIQHALAAGINFFDTANMYSNGSSEEILGRALKDFADRDEVVIATKLRHPMRTGPNGRGLSRKAVMTEVDHSLRRLGTDYIDLYQIHRNDHATPWEETLEALSDLAKAGKVRYLGASSMHAWEFAKALHLQKQHGWARFVSMQDHYNLLAREEEREMIPLCLDEGVGTIVWSPLARGRLARAWDEGKATARAETDGAFADLLYSPETEASNHAIVDAVGKVAAAHGVSRAQIALAWLRRQPVVTAPLVGAGTVQQIDDAVASLDVELGDEEVRALQAPYTPRHDWQGVSDEAEMEAIRRRIPGMSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q057</accession>
    <name>C7Q057_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6704"/>
    <dbReference type="EnsemblBacteria" id="ACU75550">
        <property type="protein sequence ID" value="ACU75550"/>
        <property type="gene ID" value="Caci_6704"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6704"/>
    <dbReference type="eggNOG" id="ENOG5032V71">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069096_0_0_11"/>
    <dbReference type="OMA" id="TATQIRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981361" evidence="2">
        <location>
            <begin position="41"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="32731" checksum="391AAA28FDE34D2D" modified="2009-10-13" version="1" precursor="true">MVNGLISRSRVQGAYALAGVLLVGSLAACGGGSSKSTAAAQTSDAGSSDSTSVAVTTSSPSPTAMSSAAYAQSLTAISGQLGPDFQAVVTAETPDAVKSALTKLSADAQALSDNGVPNDPPDALSAPNGKLSRALADLSTSADTTAKDVGTEVCTSASALAEFTRSAGATGLRDVATSLNSVDPTYGKALAGFLPAPIADQNRQLGNGQVLRHSSGPGSLTINNSGTDAVVTLTKTGTKTPVASVYVRANAKTTLSDIPGSVFDIYVTSGQDWDSAAQKFTRQCGFTKTDSTWDFSDSDWTLTLTEQVNGNLSVSPLNPGDAPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0A5</accession>
    <name>C7Q0A5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal transduction protein with Nacht domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8620"/>
    <dbReference type="EnsemblBacteria" id="ACU77438">
        <property type="protein sequence ID" value="ACU77438"/>
        <property type="gene ID" value="Caci_8620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8620"/>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_286940_0_0_11"/>
    <dbReference type="OMA" id="YRISESH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="342"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1239" mass="135275" checksum="513E1D2507B9F63A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0J7</accession>
    <name>C7Q0J7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8715"/>
    <dbReference type="EnsemblBacteria" id="ACU77530">
        <property type="protein sequence ID" value="ACU77530"/>
        <property type="gene ID" value="Caci_8715"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8715"/>
    <dbReference type="eggNOG" id="ENOG503420D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1064321_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Sensor" evidence="2">
        <location>
            <begin position="39"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="28733" checksum="43A3B12C7C9F6B6C" modified="2009-10-13" version="1">MNTEEMASLYGIPVWKRLRMYRNPVRMLFSAGVWASAWYLFSSMVVCTVLFCVITSITVTSTALVIVWAGLPLLIGTAYFIRGCAAMERGRARAVVPDGLPPMPPMDDAEGFFATLRASWRSRVTKRGLVYFSVLYVPLFVLDTVVWVVWVVFLAGVTVPIWYRYIPRTFDGRHMHGLEYGYFPNGPHGKDAIGFWIGSDLSAAVAAAAALVLLIAWNYVLVATARVHVSAVRATVVGRDPMAAARRVLDSPGPLSTPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0T6</accession>
    <name>C7Q0T6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0779"/>
    <dbReference type="EnsemblBacteria" id="ACU69714">
        <property type="protein sequence ID" value="ACU69714"/>
        <property type="gene ID" value="Caci_0779"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0779"/>
    <dbReference type="HOGENOM" id="CLU_1419178_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="191" mass="20479" checksum="E98601E68F04A558" modified="2009-10-13" version="1">MPLTWCDWEPSLLLDIPESWPPGLYVARFTVEAPLLSVMALRGRSAYVPFVVRGPLAAGFPTLVVLPFAAYVAANPWPIADVRRARALSLDRPFAGNGLPGGFAADAAFVETLTGTDFATSLDLHAGLIDPSAYRKVLFRDDLWSPQMRTAVAKASLSGTDVGGLDGVPEPSIDFAPGPDGRDDRILIRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q110</accession>
    <name>C7Q110_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Abhydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786978.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2772"/>
    <dbReference type="EnsemblBacteria" id="ACU71685">
        <property type="protein sequence ID" value="ACU71685"/>
        <property type="gene ID" value="Caci_2772"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2772"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1123615_0_0_11"/>
    <dbReference type="OMA" id="NDATHRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_4" evidence="2">
        <location>
            <begin position="163"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="246" mass="25010" checksum="DE3A2EA9BEFD7FC7" modified="2009-10-13" version="1">MTHSWLPEGPAAVRGTVVILPGRGEHGGVYERFGRRLAYDAYAVHAVDAGDAGATLAETVAKLAADAVGPVVLAGSDTGALHALALAVSGTGALGGLILVGLPGPDLPEAPADWQQELEARTACPTHRARLDGDADFVRGALSEPVSAELSAVLGDPALDVLTTPALVLHGADDRLAPASAASALADRLPGAELVLARTASHDVLNDAIHRTVAAHVVQWLERLRADGPARPLLAVRPAAAPAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K3</accession>
    <name>C7Q1K3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793461.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4872"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73732">
        <property type="protein sequence ID" value="ACU73732"/>
        <property type="gene ID" value="Caci_4872"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4872"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044209_0_0_11"/>
    <dbReference type="OMA" id="KWQTENI"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980529" evidence="3">
        <location>
            <begin position="39"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="372"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="489" mass="51048" checksum="812EA317F6948685" modified="2009-10-13" version="1" precursor="true">MSTHRHRWQRIAGAVGSLTLLLGALVVAQASHAVPARAATISQFHGVNWADPNDNFITGPNIPVGLSTADNYSTTYAKSTAILKGFQGLGANTVRLGMNAATTSGSWWGSYTATLDAATALGMNVIIAPWLQGGTVSDTNSFYQMWDTVIAKYGSSSNVYFDVMNEPYGMNATQLTNFEAGWLARYPSVPRGRVILPGLYSDGNLCAVGADSRLSGTLLSIHIYSMFGDSHTTEAAWVSDFQNNLCGYASRAVLTEFGVPMTTGVNYNGPKDGTNNVSYLYAITDTVRSMGIGSVLWVGLKDPSQTTGPGPCDNASCGITTLGGSGTNLTVSLNNQSGLDRLQWGWGTGTNPGGGGGGGGGTAGVLHAVAANRCLDVPSQATANGTQLQIWDCNGGTNQQWTALSNGELQVYGGKCLDVPGHATTAGTRVEIWDCNGGANQLWTLNSNGTVVGRESGLCLDVTGAGTANGTAVELWTCSGHSNQQWSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Q4</accession>
    <name>C7Q1Q4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase class A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6760"/>
    <dbReference type="EnsemblBacteria" id="ACU75605">
        <property type="protein sequence ID" value="ACU75605"/>
        <property type="gene ID" value="Caci_6760"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6760"/>
    <dbReference type="eggNOG" id="COG2367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073569_0_0_11"/>
    <dbReference type="OMA" id="YAVLANW"/>
    <dbReference type="OrthoDB" id="991474at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="27798" checksum="9C978AE885B3BD7C" modified="2009-10-13" version="1">MVSGPDFPDVSALPGTLAYAVPGWGEYLADEVMPLASVGKLLLLASVAQGFVSGELDPGEPLGLLEQDFSAGSGLLVTLSPRRWTLLDLARLTAAVSDNTATNALLRRVGVERVAADAGALGLERSRVLDRIREPRLAGHPPAFAVGTAREVAALAAVAAGDRGWGAVLLGWMAGCLDRSMVAAGIAHDPEDSVVRDVPLSGLWVANKTGTDVGTRCDVGVVRGARQVCYAVLTRCAAGREFDMVLAMRDVGAVVGRLAGAGGSASAEADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1T2</accession>
    <name>C7Q1T2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6792"/>
    <dbReference type="EnsemblBacteria" id="ACU75633">
        <property type="protein sequence ID" value="ACU75633"/>
        <property type="gene ID" value="Caci_6792"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6792"/>
    <dbReference type="HOGENOM" id="CLU_221481_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="29" mass="3178" checksum="F59F29EF86CA3D2C" modified="2009-10-13" version="1">MADVVFVGITIAFFGLLALIVKGVERLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1T9</accession>
    <name>C7Q1T9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795368.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6799"/>
    <dbReference type="EnsemblBacteria" id="ACU75640">
        <property type="protein sequence ID" value="ACU75640"/>
        <property type="gene ID" value="Caci_6799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6799"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="LLWHRDN"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="33007" checksum="215CAB868BE383D5" modified="2009-10-13" version="1">MDLDAVRTFVAAAETGRFQDAANDLAVTQQAVSKRIAGLEKELAVRLFARTARGAQLTIDGQAFLPHARALMQAEERAIASVRPGRRALRVDVLVMRSAMSALMRGFHETRPEIELDVVTLFDADAALAAVEAGTIDATFRYVAGSRRLPPGVESARVLDERLDLLVGPRHPLAGARSVTPAQLVGHRIWIPGLVPGVEWALYYDQLVAAFGLSIDGIGPHFGSDHLMDVIADATDVASLVGEKPRLAWSDGHDLRRIPVVDPTPVYPHSLVWRTENAHPALATLRTHLAATGEPTGSAGTWVPPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1U2</accession>
    <name>C7Q1U2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YhhN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6802"/>
    <dbReference type="EnsemblBacteria" id="ACU75643">
        <property type="protein sequence ID" value="ACU75643"/>
        <property type="gene ID" value="Caci_6802"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6802"/>
    <dbReference type="eggNOG" id="COG3714">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1234356_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31885">
        <property type="entry name" value="PTHR31885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="25411" checksum="506D16444F287A74" modified="2009-10-13" version="1" precursor="true">MPLTLTLLTLLVALADWIAVSRRAMDPTSVGARHAEYVAKPLTMVFLIGAALAIADAHARSGIPGPHRATAYLTIAAVAALVLSAIGDVFLMLPEDSSAADRNFVIGLGAFLLAHVAYIAAFVRLHAHGGYAISFVVTGLVLAGAMFATVGLRIRRAAGEEDPALAVPVLAYVSVISVLVVAAWWTGDLRIIPGALLFAVSDTMIGWTRFVRKDWELDVPIIVTYHLAQILLVLGLVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q252</accession>
    <name>C7Q252_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PknH_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8774</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797313.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77589">
        <property type="protein sequence ID" value="ACU77589"/>
        <property type="gene ID" value="Caci_8774"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8774"/>
    <dbReference type="HOGENOM" id="CLU_1080497_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026954">
        <property type="entry name" value="PknH-like_Extracell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14032">
        <property type="entry name" value="PknH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981382" description="PknH_C domain-containing protein" evidence="2">
        <location>
            <begin position="34"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="PknH_C" evidence="3">
        <location>
            <begin position="88"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="28169" checksum="A0B8986F208B7648" modified="2009-10-13" version="1" precursor="true">MRFGIKGGSIAVLTTAVLATAACSSSGQIGASGAGTSAPGSPAASTGKTAVTPPNTALAPSTSGASSANSTGSTSSSGGTTTGGKSLTTDQISANLLTDKDDPGYTYDASEDGTSVTDTQDVVSSGGGACQTFVDAENGLSTKYGTTAEVDRELTKSAEGHVIEDSVLAMPSPDKALAMVSDLSGSLQSCKKLSVAISGKPGSMELSAIPQLMKHGQAGYLNYLTVGGKTVLLTADLVQVGSAVSVVVLLGPVTNDKTELGQMGSTMGHLSDLQVARLKKAQGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J7</accession>
    <name>C7Q2J7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785134.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0907"/>
    <dbReference type="EnsemblBacteria" id="ACU69839">
        <property type="protein sequence ID" value="ACU69839"/>
        <property type="gene ID" value="Caci_0907"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0907"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_4_3_11"/>
    <dbReference type="OMA" id="APYWTTY"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="48"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="43879" checksum="36CA1AD0089F166D" modified="2009-10-13" version="1">MTASAASTPSPSDRGPATRVSRRIGAIAESATLAVDAKAKALKAAGRPVVGFGAGEPDFPTPAYIVEAAVQAAQNPKYHKYTPAGGLPELKEAIAHKTLRDSGVSVSANQVLVTNGGKQAIYNAFAALLNPGDEVIVPAPYWTTYPESIQLAGGVAVDVVTDETTGYLATVEQLEAARTERTKVLLFVSPSNPTGAVYSPEQVEAIGRWALEHGLWVLTDEIYEHLVYGDARFTSILKAVPELAEQTVIVNGVAKTYAMTGWRVGWMIGPADVVKAATNLQSHATSNVSNVAQVAALAAVSGDLEAVAEMKLAFDRRRQTIVRMLNEIPGVLCPEPKGAFYVYPSVKELLGKEIRGQRPGSSAELASLILDEAEVAVVPGEAFGTPGYLRLSYALSDADLVEGVSRLQKLLGEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2R8</accession>
    <name>C7Q2R8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2901"/>
    <dbReference type="EnsemblBacteria" id="ACU71810">
        <property type="protein sequence ID" value="ACU71810"/>
        <property type="gene ID" value="Caci_2901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2901"/>
    <dbReference type="HOGENOM" id="CLU_3005702_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="56" mass="6225" checksum="D89F4730EBE64E90" modified="2009-10-13" version="1">MNGFDDYHDVDDSEPPEESPLAGWAMSEDMAAVVRARLDELDAPGEPLRGFDWADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q325</accession>
    <name>C7Q325_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4901"/>
    <dbReference type="EnsemblBacteria" id="ACU73761">
        <property type="protein sequence ID" value="ACU73761"/>
        <property type="gene ID" value="Caci_4901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4901"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_4_2_11"/>
    <dbReference type="OMA" id="RMYPLYR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="13"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="31855" checksum="17AD30AD76514367" modified="2009-10-13" version="1">MDAPMTVGGLTAIDVHTHAEVSAKGHGSLSEELDAAAGEYFKTEHRRPTLPEIAAYYRERNMACVVFTVDAESATGTPAVPNEEVAEAAAANPDVIIPFASIDPYKGRLGVNQVKRLVREFGVRGFKFHPNVQGFAPNDRLAYPLYEAIEAEGAIAVFHTGQTGIGAGARGGGGIRLKYSNPMLVDDVAVDFPDMPIILAHPSFPWQDEALAVATHKRQVHIDLSGWSPKYFPPQLVQYANTLLQDKVLFGSDYPLLTPDRWLADFAKLPIKDEVRPKILKENAARLLGLTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3C6</accession>
    <name>C7Q3C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate binding family 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5002</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5002"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73862">
        <property type="protein sequence ID" value="ACU73862"/>
        <property type="gene ID" value="Caci_5002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5002"/>
    <dbReference type="eggNOG" id="COG3533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631199_0_0_11"/>
    <dbReference type="OMA" id="GAMATHT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982854" evidence="2">
        <location>
            <begin position="32"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="3">
        <location>
            <begin position="310"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="434" mass="44306" checksum="DA5EB5BA17AD8A6C" modified="2009-10-13" version="1" precursor="true">MRRPLLSRLIPAVVLVVATTGAVAGQSAAKAAGVVPGLTGAAARQAAGPAADRFRQLTEQRVQAAAAGHGAASSAAATLHTSWGITMPVGVGTGFKALQSVVGGAQPTNGGDFVYAPTALPPGRACMEITTAYTPSGPDLWAWDWCGGRDQVGKLTAMDSTFLATYTTTVNGHPAYDLDEHQTSASGNVWTAYLYNYQTHAWDTFYTSSGTYDLSQYPFGWDMFEVYTTPDPGTGAGYYCHDLLGKPFESSSVQLLTGSTWTPAAPGNSSPDSTPPAPGSSLDCPALTITLAHPNDDWTALIGGTSGSSQSYEAEAAGNTLAGQAAVRSSSGASGGALVGYIGNGTANYLQVNNVSATTAGSHRLTIYYAAGENRSLTVSINGGAATSLTTPGTGGWDTVGSVATTVTLTAGTNTVRIGNPTGWAPDVDRIVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Z5</accession>
    <name>C7Q3Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797477.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8940"/>
    <dbReference type="EnsemblBacteria" id="ACU77753">
        <property type="protein sequence ID" value="ACU77753"/>
        <property type="gene ID" value="Caci_8940"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8940"/>
    <dbReference type="eggNOG" id="ENOG502Z8K6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038805_0_0_11"/>
    <dbReference type="OMA" id="MAQDVGF"/>
    <dbReference type="OrthoDB" id="827116at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="519" mass="55833" checksum="5BEBBA62E193EF9C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q417</accession>
    <name>C7Q417_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8962</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8962"/>
    <dbReference type="EnsemblBacteria" id="ACU77775">
        <property type="protein sequence ID" value="ACU77775"/>
        <property type="gene ID" value="Caci_8962"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8962"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_20_1_11"/>
    <dbReference type="OMA" id="ARLLWAM"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="6">
        <location>
            <begin position="24"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="504" mass="51529" checksum="83B4999C9BDAC344" modified="2009-10-13" version="1" precursor="true">MPRRSPAPSKVSETLARDRLGVTGVMFFILAGVAPLTVTAGVVPTAYAVTGLTSVPAAFLVVAVVLAVFAVGYVAMAQRIPNAGAFYAFISQGLSKPAGVGGALVAVVAYNVLQVGLYGMIGPSLQSFAADNFGLNAPWGVWAFGAWAVVTVLGLIRVDLSGHLLGVLSTIELLVIIALTVRGLAHPAAGGISAAALSPTSLHFAGLGAVLAVAVLGFTGFEQAPVFSEEARDAKRTIPLATFVSLAVIAVVYAGASWALDVHYGNQVVATAQGPASPTMLFAMAPGLLASTARTLFLTSLIAAALAFHNAVGRYMWALGRERVLPAIMGTTGSNGVPKAASGVQSLFGAVAIGLTLGLHWDPVAKLFFWGGTTGGFGILLLLAATSAAVVKYFARTPGDETVWRRLIAPVASTVLLTVMAWLCVDHYDVLLNVPPGSLATRVLPGLFAVAAVIGIGWALVLRRRQPDAYEMIGLGGAAALARTAASSTPSAAAKPARAGRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q424</accession>
    <name>C7Q424_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="10" type="ordered locus">Caci_0952</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785179.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0952"/>
    <dbReference type="EnsemblBacteria" id="ACU69884">
        <property type="protein sequence ID" value="ACU69884"/>
        <property type="gene ID" value="Caci_0952"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0952"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_1_2_11"/>
    <dbReference type="OMA" id="FHNRMRV"/>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ADK_lid" evidence="9">
        <location>
            <begin position="134"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="144"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="24060" checksum="9A29B193AC7DF743" modified="2009-10-13" version="1">MRIVLVGPPGAGKGTQASFIASHLGVPKISTGDIFRANISQGTPLGVKAKEYLDAGQLVPDELTIDIVRDRLSQPDAVAGFLLDGFPRNVAQAEELDEILADNGVTPSSGKAYLDVVLDLEVDNDEVIKRISGRRLCRNDSGHIFHVDYSPSRDGAVCDICGGELYQRSDDAEGVVRTRLEVYAAETAPIIDYYREQGVLTTIDATGEVDVITGRAFAAVDAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4L2</accession>
    <name>C7Q4L2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787274.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3072"/>
    <dbReference type="EnsemblBacteria" id="ACU71981">
        <property type="protein sequence ID" value="ACU71981"/>
        <property type="gene ID" value="Caci_3072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3072"/>
    <dbReference type="eggNOG" id="COG3346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047737_0_1_11"/>
    <dbReference type="OMA" id="TPRWWGI"/>
    <dbReference type="OrthoDB" id="1908280at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="30932" checksum="7B0E4D814DAAC1F1" modified="2009-10-13" version="1" precursor="true">MKYRFLLRPSWLAAITALIALTVAFVGLGMWQWSRAHRTHKLSPQAAAAFVTPVPLAKLLKDGSPATGDAIGHAVTVSGVFDGGHQLLVPDRRFPDGRIGYIVIAPLKLADGTVVVVSRGWSAQMITPPPAPSGQVTVVGWLSAAEPADGAPPDASDAAAKDPAHLIASVDVATLVNTWPYSNVDQAYVNQVSVSPAGAGAGAGAGDGVLTVIPAPAPPDSSSWYILNVGYTVQWWLFGVVGLFWFVTYVRRLANPIEPEDEDEDEEDEAEDGVEDEVEEDLTQPEPTPAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S7</accession>
    <name>C7Q4S7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KDPG and KHG aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793604.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5015"/>
    <dbReference type="EnsemblBacteria" id="ACU73875">
        <property type="protein sequence ID" value="ACU73875"/>
        <property type="gene ID" value="Caci_5015"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5015"/>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_2_2_11"/>
    <dbReference type="OMA" id="HGPIPEV"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="21325" checksum="88EC6B14FD24C3E5" modified="2009-10-13" version="1">MNLTDIPFRTLAIVRGTDRDAALRTVLVLAEEGLTTVEVSLTTPGALWVIEQARRELGPEAGLGAGTVVTADDAIRAVEAGAGFLVTPGLGAALREAPTTGLPMFVGASTPSEVIDADAYGATAVKLFPASHGGPRYLKALRDPFPTIAFVPVGGVDREAAPAFLAAGAVAVGVGSPLIGDAAKGGDLAALRQRAADWRAVMTEAIGAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q584</accession>
    <name>C7Q584_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyguanosinetriphosphate triphosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795581.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7023"/>
    <dbReference type="EnsemblBacteria" id="ACU75853">
        <property type="protein sequence ID" value="ACU75853"/>
        <property type="gene ID" value="Caci_7023"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7023"/>
    <dbReference type="eggNOG" id="COG0232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028163_0_1_11"/>
    <dbReference type="OMA" id="FGVYEDD"/>
    <dbReference type="OrthoDB" id="370035at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020779">
        <property type="entry name" value="dNTPase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF32">
        <property type="entry name" value="PTHR11373:SF32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="68"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="427" mass="46713" checksum="A454CC1B004AF1DB" modified="2009-10-13" version="1">MTDAYSDADRERHLPDHPSNVRRTAFERDRARVLHSAALRRLAAKTQVVAPGSSDSAFGAYLDSPRTRLTHSLECAQIGRELGKELGADPDLMETACLSHDLGHPPFGHTGEEALALAAAECGGFEGNAQSFRILVRLEAKVLGPNGELGGLNLTRAALDAATKYPWTRAEGQARGTAKFGVYADDEPVFEWMRTGAVPGRGCFEAQVMDWSDDVAYSVHDLEDALHAGYLVPKALLSLTEQAELFELTEMRYAPGASADELSEALFRLMDLDYWPGDYDGSFAAQAALKNTTSSLIGRFCQSAAAATREAAADREAETYVTGPLTRYAADLVVPRRTRLECALLKAVTALYVMQRDDARERRRLQRELVTSLAEGLSAHPEHLEPSFRAWYSDATDECTRLRVVVDQVASLTDDAAYALSRRLGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J0</accession>
    <name>C7Q5J0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797525.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77801">
        <property type="protein sequence ID" value="ACU77801"/>
        <property type="gene ID" value="Caci_8988"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8988"/>
    <dbReference type="eggNOG" id="ENOG5032SUJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046967_0_0_11"/>
    <dbReference type="OMA" id="GWRWFRS"/>
    <dbReference type="OrthoDB" id="1491179at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021944">
        <property type="entry name" value="DUF3560"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12083">
        <property type="entry name" value="DUF3560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="40006" checksum="3A193EEFE6862990" modified="2009-10-13" version="1">MTTARTDIESGPNPPPSPRGTITITHTRADGTTAVGGAKGDGSGDILKDYPQRFRWSPYLRCWVIRNSRDKQADHRKIEAAATALRAAGFEVSVTIDEDTRRTFAEAEADRYERAEARAERRQDYADAAADRSAALYSAGREKLSRIPFGQPVLTDHYSANRDRNYRARAAAQIDRSFVEADKHAHHANLAAAAAAYRGHRENVPRTLRRIEKLEAEERQLLRLLEPVDHEGGNADTSEWDAELKRRLDETREQLDYWREHVKAAEADGVKVWSKADFAKGDFVLYGGRWYEVLRVNPKSVTVPTSFNGWREPIVRANDPKFPRTATAAYYEVRGRRSADEMAAAIASADPGPTGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5J6</accession>
    <name>C7Q5J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797531.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8994"/>
    <dbReference type="EnsemblBacteria" id="ACU77807">
        <property type="protein sequence ID" value="ACU77807"/>
        <property type="gene ID" value="Caci_8994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8994"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073558_0_0_11"/>
    <dbReference type="OMA" id="HIGAGTA"/>
    <dbReference type="OrthoDB" id="1759591at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021235">
        <property type="entry name" value="DUF2637"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10935">
        <property type="entry name" value="DUF2637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="28011" checksum="E0A0FD812BD12D92" modified="2009-10-13" version="1">MREERQDIPGEALTRRAVTTITGVIAGLTFVFSFGNVAALAAYLHVPLYIGWLVGPAVDLSVVGLLLGIRYLSLHGYTDKQLEKPRRLLILCGLLTMALNTAESICAGRYGTAAFDAVAPLLLLGWSENGPWLLRQIYTVRSLHAATGPGPAAAEQASATAVVPVLDNADSGPAEPPAGQDEPAQQAGIGEDPLLARARELDKAHRRTSGRGISRDRLRDELRIQRNRASELCQRLRAEAAAAAVDAEPAADAPEREVALVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T1</accession>
    <name>C7Q5T1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase, L subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785322.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1102"/>
    <dbReference type="EnsemblBacteria" id="ACU70028">
        <property type="protein sequence ID" value="ACU70028"/>
        <property type="gene ID" value="Caci_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1102"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066424_5_0_11"/>
    <dbReference type="OMA" id="FFRRWMT"/>
    <dbReference type="OrthoDB" id="1689902at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012737">
        <property type="entry name" value="DhaK_L_YcgS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02365">
        <property type="entry name" value="dha_L_ycgS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="4"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="20886" checksum="3505FAF3E617DFB1" modified="2009-10-13" version="1">MDIHLTRAWVQAIAAAMDQHKDHLTQLDSAIGDADHGVNMQRGFTAVVAALDGYEAVGVGDVLVKTGTTLISKVGGAAGPLYGTFFRNAGKQLSGPTADAEQLSAAFDAGLAGVQKLGAAVPGDKTMVDALVPALDAFGAAARAGESDAAAAEKAAAAAETGMQDTTPLQARKGRASYLGARSIGHQDPGATSTALVFRALAEVLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T7</accession>
    <name>C7Q5T7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785328.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1108"/>
    <dbReference type="EnsemblBacteria" id="ACU70034">
        <property type="protein sequence ID" value="ACU70034"/>
        <property type="gene ID" value="Caci_1108"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1108"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_0_11"/>
    <dbReference type="OMA" id="QLDGPPC"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="39336" checksum="452C234A50ED5F17" modified="2009-10-13" version="1">MGRMERRRAGTNLAGLRDHNTALVLGLLRAADDGGSSRVQLAAETGLTPQAISKITARLLAEGLIEEAGRTASTGGKPRTILALRPEAGCAVGIELDRLSTTILLVDLAGTTQKRWSVDAGLATGTPEQTVVMLAEQVRQAVDAAPSGARLFGVGVGARGPLDYVTGMLHRPAGLPAWDAFPLREALAARLDGVGVDGLDSPTVLLDKDTNTAALAAPAHGSTAYLHLADGLGAGMLLNGIIYRGARTNAGEFGHQVVEADGPLCTCGARGCLEALCMAALADGDPQTAARWLGLGAANLVRLLDIDRILLGGHRIFAAPDVYLRAVADQIAGHLPDPVWQDVQVSLTPAGADAVAVGAAHLVLDTMLAPHAHQPPVVVTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5V5</accession>
    <name>C7Q5V5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_1126</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785346.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1126"/>
    <dbReference type="EnsemblBacteria" id="ACU70052">
        <property type="protein sequence ID" value="ACU70052"/>
        <property type="gene ID" value="Caci_1126"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1126"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023176_0_0_11"/>
    <dbReference type="OMA" id="HAGHGVP"/>
    <dbReference type="OrthoDB" id="1753926at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982549" evidence="9">
        <location>
            <begin position="26"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="10">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="11">
        <location>
            <begin position="333"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="560" mass="57072" checksum="2CF5BACD18BCCB22" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5X8</accession>
    <name>C7Q5X8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785369.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1149"/>
    <dbReference type="EnsemblBacteria" id="ACU70075">
        <property type="protein sequence ID" value="ACU70075"/>
        <property type="gene ID" value="Caci_1149"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1149"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_0_11"/>
    <dbReference type="OMA" id="QCMAWRI"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="28"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="36343" checksum="27FC8934FEEA5756" modified="2009-10-13" version="1">MSDPADLSGPVSGWLSESGIEHALPLTLTRVGVGQSNLTYAVTDATGAPDRRWILRRPPLGHLLASAHDVAREARILTALQDSDVPVPRVFGVWTADGVPMVLMEFVDGLVLDREDVVAGVSEPTRHAVGLAIARALAPVHAVDLDKTGLVDLASHKPYAERQLKRWTTQWQHSKTRESADLDTLTARLASAIPEQRELTLVHGDFHMRNVIVSPADGSVASVLDWELCTLGDPLADVGTLLAYWPAADEAGQGLLSFSTLPGFPDREEMAAAYLDASGRDGSALAFWHALGLWKIAIIAEGVLRRVQDEPRNRAAAFAPTTEQIDSLIAKALRTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q634</accession>
    <name>C7Q634_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prmC</name>
        <name evidence="8" type="ordered locus">Caci_1206</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1206"/>
    <dbReference type="EnsemblBacteria" id="ACU70131">
        <property type="protein sequence ID" value="ACU70131"/>
        <property type="gene ID" value="Caci_1206"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1206"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_4_0_11"/>
    <dbReference type="OMA" id="FDARYWE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="29"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_25" evidence="6">
        <location>
            <begin position="135"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="303" mass="33340" checksum="4F42E904E5C549E6" modified="2009-10-13" version="1">MSDSTPVTQDPTGPPQAGKPLSLLRAEIAQASLRLAEAGVGSPRHDAEELAAWVHGVRRTDLHRVPDHDFDARYWEVIARRANREPLQHITGAAYFRYLELAVGPGVFVPRPETEVMVGWAIDKLRALDVAEPLIVDLCTGSGAIALSIAQEVPRARVHAVELSEDAYTWASRNIAASEAGERVTLHLADAVTALPELDGRVDVVVSNPPYIPLTEWEYVAPEARDHDPELALFSGPDGLDLIRGLERTAQRLLKPGGWSAFEHSDKQGGEVQRIFLEERGWAEASDHRDLTNRPRFVTARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F0</accession>
    <name>C7Q6F0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3249"/>
    <dbReference type="EnsemblBacteria" id="ACU72156">
        <property type="protein sequence ID" value="ACU72156"/>
        <property type="gene ID" value="Caci_3249"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3249"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039068_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="MTs_g-TMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020803">
        <property type="entry name" value="PKS_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00828">
        <property type="entry name" value="PKS_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_MT" evidence="3">
        <location>
            <begin position="61"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="2">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="2">
        <location>
            <begin position="132"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="2">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="41246" checksum="E2678D46D2FB8B2A" modified="2009-10-13" version="1" precursor="true">MKADMNTAVERYYDTTLDLYEELWGEHVHHGFWDEGERPDADGADRHRATDRLVHELVSYAGVPDGARVLDVGCGIGGPALYLAGALGCAVVGVTLSASQAARAGEKAQEAGLADRAEFHQLDALSTGFPDASFDVLWAVESLMHIADREAFFAEAMRLLRPGGRLAIATWSQRDGELSQDEQELIDQILKHQVMPSFSSLEEHERMANAAGFTEVASVDWSRAVANSWDPEFALIKKPEHGRATMVSLARERGADVLGFFYAGPLMKKGFDTGVVTYGAIRAVKPVEASRNADTFNEVVELLRVVLDQDAAWSASITPATTLDRDLEMESIELTAWSKVVQARYGAAADLAAHVAGLGVDQIIALTVGDIAAYVNAQADGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F2</accession>
    <name>C7Q6F2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787451.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3251"/>
    <dbReference type="EnsemblBacteria" id="ACU72158">
        <property type="protein sequence ID" value="ACU72158"/>
        <property type="gene ID" value="Caci_3251"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3251"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187737_0_0_11"/>
    <dbReference type="OMA" id="METTALM"/>
    <dbReference type="OrthoDB" id="1926658at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="1">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="89" mass="9419" checksum="559C58D0524079D8" modified="2009-10-13" version="1">MSSHDDIKKFAFEALGEMNYDTAGFDGETQLGAAGVDLESLALAELGVRVEERFGIRFSDDELDELATLTIDEFCAAVAGRLAAAATSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V0</accession>
    <name>C7Q6V0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795691.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7133"/>
    <dbReference type="EnsemblBacteria" id="ACU75963">
        <property type="protein sequence ID" value="ACU75963"/>
        <property type="gene ID" value="Caci_7133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7133"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_3_11"/>
    <dbReference type="OMA" id="HHVIFSG"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="9"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="4">
        <location>
            <begin position="364"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="481" mass="51348" checksum="2AD2011D82012E89" modified="2009-10-13" version="1">MPGTTTRTFDVIVIGAGPVGENVADRTTAAGLDTVIVEAERVGGECSYWACDPSKALLRPVLLHSELRGTPGLESAANQTLDAAAVLRHRNTMASEWDDAGQVEWLNKAGISLIRGHGRLAGPKEVTVTTPEGDVLLLTARHAVAVCTGTTAALPPLPGLEELRPWTSREATSAKEVPARLAILGAGVVATEMATAWQALGSQVTLIAREPGLLPRVEQFAADLVTERLRESGVDIRFDSGIAGAVRSPDSGDVHITLVDGSEVVVDELLLATGRAPRTDDLGMETVGLRAGDWLAVDDLFTVEEVDGEWLYAVGDVNRRALFTHQGKYQARIAGAVIAARAHRRPLDIRRWSRFVGTADRVAVPQVVFTDPEIAAVGLTTAEAERTGQVVDVVDYEIGQVAGAALHTVGYRGHARLLIDPRRRTVVGATFAGAGVAELLHSATIAITGEMPVERLWHAVPAFPTISEVWLRLLETYRDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7A9</accession>
    <name>C7Q7A9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M16 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1272</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1272"/>
    <dbReference type="EnsemblBacteria" id="ACU70197">
        <property type="protein sequence ID" value="ACU70197"/>
        <property type="gene ID" value="Caci_1272"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1272"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_1_1_11"/>
    <dbReference type="OMA" id="YDVGSRH"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="2">
        <location>
            <begin position="35"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="3">
        <location>
            <begin position="194"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="470" mass="51458" checksum="D387AF7EB9898D94" modified="2009-10-13" version="1">MTEVKSEPGETEAEKAAAASFPWPIHEAELDNGLRVVVSPDPTTPIAAVNLWYDVGSRHERAGKHGFAHLFEHLMFEGSAHVAKGEHFEWVTAAGGAAINATTSPDRTNYFQVMPSSQLELALWLEADRMGSLALTQETLDNQREVVKNERRQRYDNPPYGRWVEYALELTFPEGHPYHHTTIGSMEELQEAALEDFQDFNAVYYSPNNAVLTVAGDVDVDEVVRLAEKYFGGITRHGDIPPAPDGELPALKIGETKRLVVPDDSVPRPMTFFMFRSPDARDEDFAAVEVLATVLGRGRGARLYRKLVTEKNLAQREESYTSVWNLAYGASVFFGLFSPRDGVEAADVEREFTAVLDALTDGSDPVSEAELGRATALLTSDWLRSVSELGGRADLLGQYATVDGDPKLVREYLARLEAVTAEDVQRVAALILPDDNRVVIEYVTSATPDADPADGADTDGAGTDAEEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7B1</accession>
    <name>C7Q7B1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase, large subunit</fullName>
            <ecNumber evidence="4">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785493.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1274"/>
    <dbReference type="EnsemblBacteria" id="ACU70199">
        <property type="protein sequence ID" value="ACU70199"/>
        <property type="gene ID" value="Caci_1274"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1274"/>
    <dbReference type="eggNOG" id="COG1884">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009523_5_1_11"/>
    <dbReference type="OMA" id="CGVAIDS"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="3">
        <location>
            <begin position="29"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="563" mass="61484" checksum="8B911CDAF93DE4F8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7N1</accession>
    <name>C7Q7N1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787517.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3317"/>
    <dbReference type="EnsemblBacteria" id="ACU72224">
        <property type="protein sequence ID" value="ACU72224"/>
        <property type="gene ID" value="Caci_3317"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3317"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_2_11"/>
    <dbReference type="OMA" id="DYAPGND"/>
    <dbReference type="OrthoDB" id="538961at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982612" evidence="1">
        <location>
            <begin position="37"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="42"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="41136" checksum="42FB7A9CFA3A4F72" modified="2009-10-13" version="1" precursor="true">MFSSRVPARLRAAVAIGAVTVLAAAGCSSSTSGKSAAKGDSPITIGLITALTGSNKALGPDHLNGFQLYLDNHGNKLGGHTVKLDVGDEANGGAAAVPVAKKMIEQDHVLAIAGIVATPTIQAVVPIATAAGVPVVNTGGRPTMKDVSHLWTMSFMSTDPGGAMGPYMAQNVGGSVYAFGPDYQGGYDQLRGFTDSFAKAGGKLANDGGKPTFTPFPATSDFTPYLAKVKASGAKAIYCFYTGASAIAFVKDWSQSDAKDIPLYAAGFITEGGALKAEGTAANGIITSMNYSPDISSAANRAFVSAWGQKYNGEAPPATAMYSWDAASVLDQAIAKAGSNLTPEAINAAIKAMGQIDSPRGTWQLSSDTHVPVQKWYLRKVEMDGTALANVKVGDLATIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7T2</accession>
    <name>C7Q7T2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787568.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3369"/>
    <dbReference type="EnsemblBacteria" id="ACU72275">
        <property type="protein sequence ID" value="ACU72275"/>
        <property type="gene ID" value="Caci_3369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3369"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_5_11"/>
    <dbReference type="OMA" id="FYTATHK"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18971" checksum="F4A571A8933C22DE" modified="2009-10-13" version="1">MRDPSEFDAFYAGSVRRVTSHLYAMTGSRAEAEDLVQEAYTRAWQNWGKVSGYGDPEGWVRAVAFRIRVSAWRKAVNRATAHRRHGVPEPDPGANPDYVAIIAALRRINPQQRQAVVLYHLVGLSIEQIALETGVAVGTVKARLSRGRQALAPHLSDAVPAFPSFAKEASGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7W1</accession>
    <name>C7Q7W1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793857.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5269"/>
    <dbReference type="EnsemblBacteria" id="ACU74128">
        <property type="protein sequence ID" value="ACU74128"/>
        <property type="gene ID" value="Caci_5269"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5269"/>
    <dbReference type="eggNOG" id="COG4668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072531_3_0_11"/>
    <dbReference type="OMA" id="EDYIQAM"/>
    <dbReference type="OrthoDB" id="1810962at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16647" checksum="74639A4C29E90222" modified="2009-10-13" version="1">MSDSRDGLLAERAVRFGVHATDRYDAVRQCGELLVEVGAVAEEYVPSMRDREDEISTYIGAGVAIPHSTAAGKKYVRRDALAVLVLAEPVDWGEDQQVSLCVAIAALGDRHLDILAELAEVLMDPERAEQLHQAKTANEVIRLLQPAGKAENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8S1</accession>
    <name>C7Q8S1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785630.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1413"/>
    <dbReference type="EnsemblBacteria" id="ACU70336">
        <property type="protein sequence ID" value="ACU70336"/>
        <property type="gene ID" value="Caci_1413"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1413"/>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_358536_0_0_11"/>
    <dbReference type="OMA" id="RWGDDRF"/>
    <dbReference type="OrthoDB" id="194345at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="780" mass="86668" checksum="D78F1A743F9D9DE0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q914</accession>
    <name>C7Q914_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787627.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3428"/>
    <dbReference type="EnsemblBacteria" id="ACU72334">
        <property type="protein sequence ID" value="ACU72334"/>
        <property type="gene ID" value="Caci_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3428"/>
    <dbReference type="eggNOG" id="COG2154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109854_0_0_11"/>
    <dbReference type="OMA" id="VCLCTWQ"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="111"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23245" checksum="E82C850C9B24DFB0" modified="2009-10-13" version="1">MSELEWITPAQFHAAEGVDDWRVLAFGVCARFATDTFSAAADLAAAVSAVPGLDGANPGLDVRSDGVTIQLRAEPGHGMRAGDIALARRLSAVAVAHGARPEPATVQELNITVDALTAADIMPFWCAVLGYEQRGDEDLVDPLDRGPSFWFQDMDAPRPQRNRLHVDVFVPHDLAEARVAAALAAGGHLVSDKHAPSWWVVADAEGNEACIASWMGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q950</accession>
    <name>C7Q950_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate binding family 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3464</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787663.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3464"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH28">
        <property type="family name" value="Glycoside Hydrolase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72370">
        <property type="protein sequence ID" value="ACU72370"/>
        <property type="gene ID" value="Caci_3464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3464"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016031_8_4_11"/>
    <dbReference type="OMA" id="LEMSHVE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16990">
        <property type="entry name" value="CBM_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982921" evidence="5">
        <location>
            <begin position="40"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="524"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="649" mass="66094" checksum="A2C07EFB5249AA6A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q976</accession>
    <name>C7Q976_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase PA-phosphatase related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792125.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3490"/>
    <dbReference type="EnsemblBacteria" id="ACU72396">
        <property type="protein sequence ID" value="ACU72396"/>
        <property type="gene ID" value="Caci_3490"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3490"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_7_0_11"/>
    <dbReference type="OMA" id="ANHSKIS"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acidPPc" evidence="1">
        <location>
            <begin position="80"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="20129" checksum="359C3E15BE952E95" modified="2009-10-13" version="1">MTEPSLHPLVGQISPLARRFRRLADLDAAAYAAVARTPTPSAVDSALRTLSHTANHSKISLSIAALLATRPGPPRQAAVAGVSAVALASASANLLAKRLARRHRPPRAEPGLFPRRYVVMPRSASFPSGHTASAVAFAVAVGRVLPGAAVPLGALAAVVGYSRVHTGVHYPGDVVGGAVLGAASAAVVLRVRRGVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9A9</accession>
    <name>C7Q9A9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793984.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5396"/>
    <dbReference type="EnsemblBacteria" id="ACU74255">
        <property type="protein sequence ID" value="ACU74255"/>
        <property type="gene ID" value="Caci_5396"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5396"/>
    <dbReference type="eggNOG" id="COG1938">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055821_1_0_11"/>
    <dbReference type="OMA" id="IEPNMRW"/>
    <dbReference type="OrthoDB" id="834483at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008492">
        <property type="entry name" value="DUF774"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028754">
        <property type="entry name" value="UCP028754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="33365" checksum="721B103F0818320B" modified="2009-10-13" version="1">MIEFDGNMPDLVDPVAICAFEGWNDAGEAASNAVKHLAEAYAGAGRMFAALDGEDYYDYQVHRPMVAAVDDRRQVIWPTTRFSVVRAPARLLPGDAHEEPRDLVLVHGVEPNMRWRSFCEEVLGLARDLGVGQIITLGAYLADVPHTRPTPVTGTSSDEAYQALFDVEPPTYEGPVGITGVFQEACHHAGIPLMSFWAAVPHYVAHPPVPKATLALLRRLEDVLDLSVPTKRLAEEAQSWEAGVDELAENDAEVGEYVRTLEEQRDNEDAADSPEASGEAIAREFERYLRRQERRRGSSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9I7</accession>
    <name>C7Q9I7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74333">
        <property type="protein sequence ID" value="ACU74333"/>
        <property type="gene ID" value="Caci_5474"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5474"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_0_11"/>
    <dbReference type="OMA" id="IGYWIDT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="20597" checksum="F302F060480F1A3C" modified="2009-10-13" version="1">MTAASDSPKALAPGVVPPETIDLDGYHLRRATAEDTEALHEAVKASFAELHPWMPWCTEPVEIASQRDFIERSETGWTAQTAFNWLIIDAGGHLIGTIGLMDRIGPGGLEIGYWLRSDATGRGVMTRAAARVTDIALALPGVERVEIHCDAANVRSAAVPRRLGYRLDREAHAEPTSPGESGLSQYWVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9R7</accession>
    <name>C7Q9R7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glutamine synthetase</fullName>
            <ecNumber evidence="7">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Oligomer of 12 subunits arranged in the form of two hexagons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795964.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7410"/>
    <dbReference type="EnsemblBacteria" id="ACU76236">
        <property type="protein sequence ID" value="ACU76236"/>
        <property type="gene ID" value="Caci_7410"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7410"/>
    <dbReference type="eggNOG" id="COG0174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017290_1_2_11"/>
    <dbReference type="OMA" id="PHPHEFE"/>
    <dbReference type="OrthoDB" id="416474at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001637">
        <property type="entry name" value="Gln_synth_I_adenylation_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00182">
        <property type="entry name" value="GLNA_ADENYLATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="8">
        <location>
            <begin position="104"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="4">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="474" mass="53006" checksum="5B86059A673BA3CC" modified="2009-10-13" version="1">MFSNADEVLKYLRDNDVKSVDVRFCDLPGVMQHFTVPVESFDADVFSHGLAFDGSSIRGFQAIHESDMQLLPDPTTARLDPFRAEKTLNINFFIHDPLTGEAYSRDPRNVAKKAEAYLKGTGIADTCYFGPEAEFYVFDDVRFASGPEESYYHIDAEAAFWNTGRAEEGGNRGYKPRVKGGYFPVAPNDHYTDLRATMSRTLIDSGLIVERQHHEVGSAGQAEINYRFNTLLAAADDLMLFKYIIKNVAWQAGKTATFMPKPVFGDNGSGMHCHQSLWKDGAPLFYDEVGYAGLSDTARHYIGGLLKHAPSLLAFTNPTVNSYRRLVPGYEAPVNLVYSQRNRSACIRIPITGSNPKAKRIEFRCPDPSSNPYLAFSAMMMAGLDGVKNKIEPMAPVDKDLYELPPDEHASIPQVPGSLPAVLDSLEADHGYLLEGGVFTQDLIDTWISYKREREVDPVRLRPTPHEFELYFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA81</accession>
    <name>C7QA81_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785773.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1558"/>
    <dbReference type="EnsemblBacteria" id="ACU70479">
        <property type="protein sequence ID" value="ACU70479"/>
        <property type="gene ID" value="Caci_1558"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1558"/>
    <dbReference type="eggNOG" id="COG2905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172512_1_1_11"/>
    <dbReference type="OMA" id="RWLDSDH"/>
    <dbReference type="OrthoDB" id="2069996at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015035">
        <property type="entry name" value="DUF1918"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08940">
        <property type="entry name" value="DUF1918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1918" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="7481" checksum="D5E63E53783CBE63" modified="2009-10-13" version="1">MRASVGDRLHVHAAHVGEADRTGEIIEVKGDSGTPPYLVRFDDGHQGLVFPGPDAVVECAAGGDTAPDSPSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAA4</accession>
    <name>C7QAA4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7 8">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recA</name>
        <name evidence="13" type="ordered locus">Caci_1581</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785796.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1581"/>
    <dbReference type="EnsemblBacteria" id="ACU70502">
        <property type="protein sequence ID" value="ACU70502"/>
        <property type="gene ID" value="Caci_1581"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1581"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040469_3_2_11"/>
    <dbReference type="OMA" id="DYGEQAL"/>
    <dbReference type="OrthoDB" id="1080436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="11">
        <location>
            <begin position="38"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="12">
        <location>
            <begin position="202"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="332"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="68"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU70502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="40278" checksum="951B184FD531665D" modified="2009-10-13" version="1">MAATTTDREKALDAALAQIERNFGKGSVMRLGARSVQPIDIIPTGSIALDVALGIGGLPRGRVVEIYGPESSGKTTIALHAVANAQKAGGQAAFIDAEHALDPDYARNIGVDTDLLLISQPDTGEQALEIADTLIRSGALDIIVIDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGVIHQTNTTVIFINQLREKVGVMFGSPETTTGGRALKFYASVRLDIRRIETLKDGTEAVANRTRVKVVKNKVAPPFKQAEFDVVFGSGISREGSLIDMGVEHGFVKKAGAWFTYSEGQLGQGRENARRFLKENPDVADGLEKLIKEKLGIGPKLDEPADGATATVPAPAASADGAPAEEVAAKPAKTSRARKTAAAAAGAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB6</accession>
    <name>C7QAB6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3509"/>
    <dbReference type="EnsemblBacteria" id="ACU72415">
        <property type="protein sequence ID" value="ACU72415"/>
        <property type="gene ID" value="Caci_3509"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3509"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="EGHRIGI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22927" checksum="BA4C06A17BD5CE67" modified="2009-10-13" version="1">MLITAGTELMRSGLSAMLGRLPGVAQVQECADARQAVTLVEGHRIGIVVTAPPMPHGDFEALAAGASRNKARTLVVLRDYDLPPNEVVAQAVAMPADGYLLESELTAASLADTLVRVDHGEAPVPASLARGLLSRLRSVESEPIRRQFLLTPRELEVLELLVEGLSNKEIARRLSMSEHGVKRHVGAVLAKLNCPNRTVAVAFVLQKGLMYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAT1</accession>
    <name>C7QAT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794133.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5545"/>
    <dbReference type="EnsemblBacteria" id="ACU74404">
        <property type="protein sequence ID" value="ACU74404"/>
        <property type="gene ID" value="Caci_5545"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5545"/>
    <dbReference type="eggNOG" id="COG3871">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150521_0_0_11"/>
    <dbReference type="OMA" id="DEPYWAK"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="19"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15772" checksum="D7117613D0618CC7" modified="2009-10-13" version="1">MELLDHLSDADRQRVLGRLNSNLMVWLTTVRPDGQPVSVPVWFLAREDGTLLIYSRANKAKLANIAANPKVSLGLDVTDIGRNIVRLEGVAHHDPSLPRAHEHPAFLAKYIERMGAMFDTPENFGDQFTAGLVIQLTKVYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAT9</accession>
    <name>C7QAT9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794141.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5553"/>
    <dbReference type="EnsemblBacteria" id="ACU74412">
        <property type="protein sequence ID" value="ACU74412"/>
        <property type="gene ID" value="Caci_5553"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5553"/>
    <dbReference type="eggNOG" id="ENOG502Z7YZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071811_0_0_11"/>
    <dbReference type="OMA" id="GYWTTVK"/>
    <dbReference type="OrthoDB" id="1520004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="27497" checksum="C2CE0FD86A72A912" modified="2009-10-13" version="1">MATKLSQIIAIEKGVKSKSYADLTQAHHDVQKQPLLTGLSRTYQPKDEDGEQLPPESTRVQVKAEDVLRQIAVGLTRLFDVTATKDWANCVAHADVVVEGTTLLRDVPVSYLLFLEKQLADLNTFVKKLPVLDAAESWTHDPSTDWFRTEAVRTLRTKKVPRNHVKAEATEKHPAQVEVYYEDIAVGYWTQTKFSGALPAQRVNELVERVEKLSQAVKFAREEANTFEVTDQRVGEAVFGYLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV2</accession>
    <name>C7QAV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794154.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5566"/>
    <dbReference type="EnsemblBacteria" id="ACU74425">
        <property type="protein sequence ID" value="ACU74425"/>
        <property type="gene ID" value="Caci_5566"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5566"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_1_11"/>
    <dbReference type="OMA" id="AFISTEY"/>
    <dbReference type="OrthoDB" id="922937at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="34"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30948" checksum="118059A2F5B373E2" modified="2009-10-13" version="1">MDKHELGAFLRSRRERIQPQDVGLPAGPRRRTPGLRREEVAVLAHISTEYYVRLEQGRAPRPSSEVLAGIAGALRLTDAESDHLHLLAGTAPNRAGLHRRDVRPSILRLLERLPQTAAFVTSALFEVLAWNRLAAALMEDYSKLAPRDRNLARRAFLGPADPDAPLYGISDAAEFRSNVVMELRSALARYPADPSVAGLVDELRDGSAEFVRLWERHDVQATTMLTKTFRHPVVGDVTVDCDSLDLADRDQHLVLYSAPAGSPDAEALAFLDVLGAEGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB09</accession>
    <name>C7QB09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lysozyme</fullName>
            <ecNumber evidence="5">3.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5623</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.17" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5623"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74482">
        <property type="protein sequence ID" value="ACU74482"/>
        <property type="gene ID" value="Caci_5623"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5623"/>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_0_2_11"/>
    <dbReference type="OMA" id="IGMNDVQ"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982971" evidence="3">
        <location>
            <begin position="37"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-3" evidence="4">
        <location>
            <begin position="378"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="426" mass="42529" checksum="6DDB643421FD91B3" modified="2009-10-13" version="1" precursor="true">MKTPGPGRRRMAVRSGALLVAAIAATATALSHSASASPQAAAAGSSVFSVAPYVDMSNGQEPVLDTAITGHGLKAYTAAFIIGVGCNQEWGDTLPVGNDSFTDPEIARAKSEGASVIISSGGAAGEALAWTCTNQSSIQAGYQAIISDYGVKQLDFDVEGAAVADQSAAARNFTAMKALKSANPGLQFSMTLPVLPSGLTQDGVNILQTAKNNGVKIDVVNLMTMDYYQGQQDMGAAAVKAAQSTLAQMKAVDSSYTYANVGITPMIGVNDDGSVFTAANAATVEQFASANGVGRLAYWSIDRDQPCPGGSGGGASSTCSGVGNAKLAFADAFVPYTGSGGGTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGGSCSAAPWSASTSYVPNDVVSYNGHSWTATYWSTGVTPGSAIAWNIWKDDGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCD8</accession>
    <name>C7QCD8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ordered locus">Caci_5728</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794315.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5728"/>
    <dbReference type="EnsemblBacteria" id="ACU74586">
        <property type="protein sequence ID" value="ACU74586"/>
        <property type="gene ID" value="Caci_5728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5728"/>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_3_0_11"/>
    <dbReference type="OMA" id="HTEPENI"/>
    <dbReference type="OrthoDB" id="1278103at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21313" checksum="6C06898FF90477D2" modified="2009-10-13" version="1">MSRVGRVERTTGETGVLVEVDLDGTGEAEISTGVGFFDHMLHQLAKHGLFDLTVKTEGDLHIDGHHTVEDTALALGAAFREALGTKAGLRRFADARVPLDETLAEVVVDLSGRPYLVHEMPEGLAPMIGDFDTELTRHIFESFVAQAQICLHIRVPYGRIAHHVVEAQFKALARALREACTLDPRVSGIPSTKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCI0</accession>
    <name>C7QCI0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7619</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796168.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7619"/>
    <dbReference type="EnsemblBacteria" id="ACU76443">
        <property type="protein sequence ID" value="ACU76443"/>
        <property type="gene ID" value="Caci_7619"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7619"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_0_11"/>
    <dbReference type="OMA" id="GSDTDRM"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="111"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="40015" checksum="CC716C771AD028C8" modified="2009-10-13" version="1" precursor="true">MDDQTQRPRRRTGPDSGSMSRRRVVIICAASLAVLAVAGTTGLWTMYTRLNDNIRTVDIHADDAPGPADTMKPQPGSPSSSARASMNVLLIGSDDRDGANAQYGDANSGARSDTTMLLHVAADRKSATVASIPRDSMVQTPACTKSDGTQSQPQFGMFNAAFSIGGAACTVKTVETLSGLTVDHVLVVDFTGFKKIIDAIGGVPVHLDQAIDDPDSHLNLPAGTTVVDGEQALAFVRARHNLGNGSDIGRMSRQQVFLNDALDTITANGTLDDPAKLYKVLDAATKALTTDPALGSLPALADFASDVKQVPRQQITYLTVPWQWYQPDPNRVQLAPLAQELFTAMLQDTPVPAEVLALAAKQGEQVTPEDGSPNGAPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCL7</accession>
    <name>C7QCL7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glutaminase</fullName>
            <ecNumber evidence="3 5">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glsA</name>
        <name evidence="6" type="ordered locus">Caci_7656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3 5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796205.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7656"/>
    <dbReference type="EnsemblBacteria" id="ACU76480">
        <property type="protein sequence ID" value="ACU76480"/>
        <property type="gene ID" value="Caci_7656"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7656"/>
    <dbReference type="eggNOG" id="COG2066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027932_1_1_11"/>
    <dbReference type="OMA" id="RPRNPFI"/>
    <dbReference type="OrthoDB" id="1288854at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="33055" checksum="27C2A14C4096792E" modified="2009-10-13" version="1">MANEEGAAVSVDDIAYDALLEWIADEVAPYVGDGRVADYIPALAQVPPDRFGMALATVDGHLYGVGDFRERFSLQSISKVFTLALVMAGDAGALRGRVGVEPSGNAFNSLIQLEYERGIPRNPFINAGALVVTDILQSQTGDAAGTVLDFLRTESDDHTITIDGAVAASEAEHGDLNLALAHFMAAYGNIENPVDLTAEHYFRHCSIAMSCAETAMAALFLARHGVRTGGTRLLPVLGAKRVNALMMTCGAYDAAGDFAFRVGLPGKSGVGGGILAVVPGRAALCVWSPALDPHGNSVAGVEALDRFSAATGWSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD48</accession>
    <name>C7QD48_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786052.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1837"/>
    <dbReference type="EnsemblBacteria" id="ACU70758">
        <property type="protein sequence ID" value="ACU70758"/>
        <property type="gene ID" value="Caci_1837"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1837"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064918_0_0_11"/>
    <dbReference type="OMA" id="LGCHIEM"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="46"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="33617" checksum="C6DA835F2CA5A2B3" modified="2009-10-13" version="1">MASPLDLHWNHGVRRWSSATEPPIQVHAYDERTVILRQSKSTNYEAPFIYLLFGADRALLLDTGATADPAVFPLRATVDELITNWLQQHPRDGYELVVAHTHSHGDHVAADAQFTGRPDTLVVAKEPEAVRHFFGFDDTRWPDQEVEVDLGDRVLRALGAPGHHAAGVVFHDPATGFLLTGDTVYPGRIYVADYAQLVATLNRLVAFCAAHKVTWVMGCHVEMTDRPYRDYPIGSTYQPRERALPMTVAQLTALRDAAVQVDGRRGEHRFEDFIVFHEPAGWAAILFRMRGFRARMLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR3</accession>
    <name>C7QDR3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methylamine utilization protein MauE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_5829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">One-carbon metabolism; methylamine degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5829"/>
    <dbReference type="EnsemblBacteria" id="ACU74687">
        <property type="protein sequence ID" value="ACU74687"/>
        <property type="gene ID" value="Caci_5829"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5829"/>
    <dbReference type="HOGENOM" id="CLU_101331_1_0_11"/>
    <dbReference type="OMA" id="VACRCFG"/>
    <dbReference type="UniPathway" id="UPA00895"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030416">
        <property type="term" value="P:methylamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009908">
        <property type="entry name" value="Methylamine_util_MauE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07291">
        <property type="entry name" value="MauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981563" description="Methylamine utilization protein MauE" evidence="11">
        <location>
            <begin position="29"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="MauE" evidence="12">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU74687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="17455" checksum="AB37A515089BC78E" modified="2009-10-13" version="1">MSYVDPACRGLLAAVFLVAVVGKVRSRAAFSAFAASLADVRLLPVRLRRAAAVGVTAAEAVAAVLLLTPLAEAAVAGFALAFALLAVFAAGVALALRRGEAIRCLCFGSDAGAMDRSHVVRNAVLAAVALTGLISSLTSTAAAAPAGLIGAAGAGVALGALATRWDDLRYLLSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE55</accession>
    <name>C7QE55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7819"/>
    <dbReference type="EnsemblBacteria" id="ACU76643">
        <property type="protein sequence ID" value="ACU76643"/>
        <property type="gene ID" value="Caci_7819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7819"/>
    <dbReference type="eggNOG" id="COG1633">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082377_0_0_11"/>
    <dbReference type="OMA" id="WARRLMG"/>
    <dbReference type="OrthoDB" id="1414501at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="23832" checksum="972C2C2330A0DD89" modified="2009-10-13" version="1">MSYEIAVTDFLGLVAYGELTAFERLAADSGLAPTLDGKAQVAGMAAAEFDHFRRVRDRLTELGADPTEAMEPFAAPVDAFHEHTKPSGWLESLVKAYIGDTLTADFYREAARYLDPESRTVVEGVLEDLGHSAFVVEHVRAAIEKDPKIAGRLALWGRRIMGEALTQAQHIAARRAALAALLAGLLSAPDCDTAVDLAEVGKMLTRLTEAHGARMATLGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE79</accession>
    <name>C7QE79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7843</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796392.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7843"/>
    <dbReference type="EnsemblBacteria" id="ACU76667">
        <property type="protein sequence ID" value="ACU76667"/>
        <property type="gene ID" value="Caci_7843"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7843"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="ISHATCK"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="161"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24592" checksum="EC82C9277113503E" modified="2009-10-13" version="1">MSRILIADDQALLRASLRSLVNGYDDCQVVGEAANGAQAVHMAAGLRPDLVLMDVRMPVLDGIEATRRITAADPGVRVLILTTFDLDEYVYEGLLAGASGFLLKDSPPADLVTAIEVIRSGEALLTPAATRRLITEFVRSRRTPNRATATAATTANAIAPPDPALDGLTAREREVLTLVARGKSNTEISTELFVSMSTVKTHMSALLAKLGARDRAQLVIRAYEGGLVRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE98</accession>
    <name>C7QE98_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, PucR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1869</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CdaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1869"/>
    <dbReference type="EnsemblBacteria" id="ACU70789">
        <property type="protein sequence ID" value="ACU70789"/>
        <property type="gene ID" value="Caci_1869"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1869"/>
    <dbReference type="eggNOG" id="COG2508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017436_3_0_11"/>
    <dbReference type="OMA" id="HFHYNTM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041522">
        <property type="entry name" value="CdaR_GGDEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025736">
        <property type="entry name" value="PucR_C-HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042070">
        <property type="entry name" value="PucR_C-HTH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012914">
        <property type="entry name" value="PucR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17853">
        <property type="entry name" value="GGDEF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13556">
        <property type="entry name" value="HTH_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07905">
        <property type="entry name" value="PucR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PucR" evidence="3">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF_2" evidence="5">
        <location>
            <begin position="378"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_30" evidence="4">
        <location>
            <begin position="545"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="609" mass="64518" checksum="111E66ED82A9E879" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG5</accession>
    <name>C7QEG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1936"/>
    <dbReference type="EnsemblBacteria" id="ACU70856">
        <property type="protein sequence ID" value="ACU70856"/>
        <property type="gene ID" value="Caci_1936"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1936"/>
    <dbReference type="HOGENOM" id="CLU_1999791_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="12886" checksum="B236936B684326FC" modified="2009-10-13" version="1">MTPVDGLVAEELVGDGDGDGEDAADEPDGEDDADGEEPDGEEVVPVVGELVGAPSAFPCEESHAPVNAAAPSAAMPPRRIVRLVLIRFSIRQNPHGARKERRAAADEPPCREYGARYDAAGPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEQ3</accession>
    <name>C7QEQ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792552.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3940"/>
    <dbReference type="EnsemblBacteria" id="ACU72823">
        <property type="protein sequence ID" value="ACU72823"/>
        <property type="gene ID" value="Caci_3940"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3940"/>
    <dbReference type="eggNOG" id="ENOG50327E9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081556_0_0_11"/>
    <dbReference type="OMA" id="YPEVREW"/>
    <dbReference type="OrthoDB" id="1288396at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005669108" evidence="2">
        <location>
            <begin position="30"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="275" mass="30343" checksum="C66CDAFBB73E0F00" modified="2009-10-13" version="1" precursor="true">MKRFWRSIAAGAVACAALAVMVAVDKAAGQTTEYKATHHVAGGFILGWLAALCVLVLAMVSAIYFAAQSRRDRQRSRGQFTAKLHHQQLQATANQAWLDGRRLAADLKAGNRPPALKLWGIVLNDGEEVYLDVPAHYGRFYGGDGSYTQANGFFWGSAGFVLAGYALTAIGNRQQRQRAQAEAMQRWRDVQQTRVLATNERLICSVYGSWMSFYYSGVTEFYPEPAAYRMVMAFDDTTPLMISGPFTPLLTVLSTLYIYGLPALDDHPALADLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF08</accession>
    <name>C7QF08_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794495.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5908"/>
    <dbReference type="EnsemblBacteria" id="ACU74766">
        <property type="protein sequence ID" value="ACU74766"/>
        <property type="gene ID" value="Caci_5908"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5908"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_0_4_11"/>
    <dbReference type="OMA" id="FEPEVIC"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="32016" checksum="1B1D360178B1F8A7" modified="2009-10-13" version="1">MSAPEQSAEAADTVDDAAGPAYTLALDVGGTGIKAGLVTRDGTLRCTWRRATRIERGPEAVIATIADFAAELVEAAAADGTPVAAAGFALPGIINEQTGVGVFSATVGWRDVPFGELLGARLAVPIAIGHDVRAGGVAEARIGAGRGSARFVFLPLGTSIGGAIMIDGVANLGPHGMGGEFGHIVVRPGGLPCGCGLHGCLAQYSSAGAVAARYAEAAGTPNVGALDVAARLATGDPIARRIWDEAVDVLSDALLTTAALLDPDRVVVGGGLAEAGATLMTPLGEALAAKATYHALPELVTAELGDLAGCLGAGLLAWDLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF11</accession>
    <name>C7QF11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase family 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5911</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5911"/>
    <dbReference type="EnsemblBacteria" id="ACU74769">
        <property type="protein sequence ID" value="ACU74769"/>
        <property type="gene ID" value="Caci_5911"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5911"/>
    <dbReference type="eggNOG" id="COG1807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007261_1_0_11"/>
    <dbReference type="OMA" id="LYRCAPE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="46"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="644" mass="66987" checksum="F6C965525FAC5225" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF81</accession>
    <name>C7QF81_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794568.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5981"/>
    <dbReference type="EnsemblBacteria" id="ACU74839">
        <property type="protein sequence ID" value="ACU74839"/>
        <property type="gene ID" value="Caci_5981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5981"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_11"/>
    <dbReference type="OMA" id="IWETSDE"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27264" checksum="6A1E6C65423331A3" modified="2009-10-13" version="1">MDIRLDGKVALVTGGSRGIGQAIAATYAACGAQVVISSRKIDGLQRAAEEIRAEVPDAQIVPFAAHAGDPQAAHDCVQFAVETFGTLDILVNNAATNPHFGNVIDVDPPRFDKTVEVNLRGPLIWTQEAWRQAMNPESTHPGGCVINLSSVSGLQFNDPLGVYGTTKAALIHQTKHLAGELAPAVRVNAIAPGLVKTEFARMLWEGAEPDAKYPWALERLGEPQDIANAALFLASDLASWITGEVLVVDGGAMIKGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFM7</accession>
    <name>C7QFM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784261.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0011"/>
    <dbReference type="EnsemblBacteria" id="ACU68966">
        <property type="protein sequence ID" value="ACU68966"/>
        <property type="gene ID" value="Caci_0011"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0011"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_8_1_11"/>
    <dbReference type="OMA" id="VMAKAGH"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="UTRA" evidence="2">
        <location>
            <begin position="86"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="240" mass="26450" checksum="2D622F9A28344F19" modified="2009-10-13" version="1">MKRVDDRPQHARIAADLRAKILAGDITGTLPPFKRLMELYSTTTNTAQRAVALLKAEGFVEGQRGKALIIRADRIRIVDAASQFEPPASTITYQILHIGPARPPADAAQKLGLAEGETALLRKRLMLRDEEPVEIEWSFYPESVVTGTALDKPLPQRDLATAPTVLAALGWKQAGLVDEIQVREPTTEELQTLELPDEIPVMRTLRTITDAEGTVLEVTVMITSGHLYGVRYQQKLTPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFS1</accession>
    <name>C7QFS1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TrkA-N domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0055"/>
    <dbReference type="EnsemblBacteria" id="ACU69010">
        <property type="protein sequence ID" value="ACU69010"/>
        <property type="gene ID" value="Caci_0055"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0055"/>
    <dbReference type="eggNOG" id="COG1226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055253_1_0_11"/>
    <dbReference type="OMA" id="HIIVCGC"/>
    <dbReference type="OrthoDB" id="599322at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="2">
        <location>
            <begin position="121"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36550" checksum="FBE98624CC49892D" modified="2009-10-13" version="1">MLPRAVPGPLRAVLKRVLLALGILVLSAVIVYLGRDGYRDSSGKPIGWLTSFYYATVTLSTTGYGDVVPVSDSARLISTLFVTPLRVLFLLVLVGTTLEVLTERTRNEWRQERWRSKVRDHTVVVGYGTKGSSAVQTLLKHGTTPESIVVVDTDPARIAEANRRGLVGIVGDGSRSEVLERAEISKARHVVISAERDDTAVLTTLTVRRLTRRATVVASVREAENAPLLRESGASSVVTSSDTAGQLLGMATISPKVSQVVHDLLSHGEGLELLERPADTGDVDKDPRALKEPVLAVIRGSRTMRFDDVAIGTIQLTDRLVVVRSVHNRRTDPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFX4</accession>
    <name>C7QFX4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2031"/>
    <dbReference type="EnsemblBacteria" id="ACU70951">
        <property type="protein sequence ID" value="ACU70951"/>
        <property type="gene ID" value="Caci_2031"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2031"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_2_4_11"/>
    <dbReference type="OMA" id="YDKITVG"/>
    <dbReference type="OrthoDB" id="534010at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982841" evidence="1">
        <location>
            <begin position="27"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="46439" checksum="8744493E365F636C" modified="2009-10-13" version="1" precursor="true">MSMRTTRRSALRLGIGALAVAVTGGCATGGGKKTPAPAVKTGAAAQVGGTITVWSWDVAAKALKRLAPAFEQQHPGVKVNVVDIGYDNAYDKITVGLKSGSGLPDVLQVEGPKMQSYIGTFPSGFYDLSTLAAPLKAQFNAAAWATGTDANGKVYALPWDIGPCGVFYRTDIFQQAGVDPASIQTWDDYIAAGVRIKAKTGKKLLVVDPTGDSTFPMMLHQEGQGYFVGDKIAVDTPAAVKAMTVMKELNDKGLVDYEKGWDALVAATKDGTVATTPTAVWWSGTLTDEMPELKGKFAAIPLPAFTSGGIRTSNNGGSLLTISAQSKNSATAWAFIQFVLADADNQVSMLKNEGIFPAFEPALSDPYITGPQDYYGGQTTFKIFADLAKNIPAVQYTADFSKASDLINTATGAVMQGGKDPKSALDSAAQQIASATNRQIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG52</accession>
    <name>C7QG52_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4029"/>
    <dbReference type="EnsemblBacteria" id="ACU72897">
        <property type="protein sequence ID" value="ACU72897"/>
        <property type="gene ID" value="Caci_4029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4029"/>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078491_2_0_11"/>
    <dbReference type="OMA" id="QYPMELA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="65"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="22207" checksum="494150A548A17C85" modified="2009-10-13" version="1">MATSMPKMAPVKISGRLGGSAKKAEPRLSPAAKRRSVPYAVLGGALAVVFAVGFAATSLNFGGKQSYLAVVKPVRAGQVIQASDLATVQVATNAGLGLIPASAQNSVVGQAAALPLAPGALVTRREVGPASFPPAGQQVIAVAVKTGQYPMELAPGAHVIVGTAPASGSSGTATVTPLSAAPSAVVLSITPGTDSGTGSVSLLADAGSASAIAAIPAAQVQLVLSAPAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGC6</accession>
    <name>C7QGC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FMN-dependent alpha-hydroxy acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4107"/>
    <dbReference type="EnsemblBacteria" id="ACU72971">
        <property type="protein sequence ID" value="ACU72971"/>
        <property type="gene ID" value="Caci_4107"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4107"/>
    <dbReference type="eggNOG" id="COG1304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_0_11"/>
    <dbReference type="OMA" id="ENLSVPM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="308"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="40621" checksum="B25E1B11197E84FE" modified="2009-10-13" version="1" precursor="true">MSVAAPEANGAARPEAFDPGSGLEAMLTVREFEAVAQRKLDPVHYDYIAGGSRDEVTVRANEDGFGRLSLLPRVLRGSAQRDLSVTLFGGQSSMPVLISPTAFHRLVCAEGEIATARAAARAGTIMIASMASTVAVGEVAAAARAAAGDGDPTLWFQLYLQPDMDDTTALIARATDAGCRALVVTVDSPVLGANERNQRNNFDDLPPEMACENLRNLRGDEPGNVRQIAMSPELSWEHIDWLREHTRLPILLKGVLHPEDARIAIAHGIDGLLLSNHGGRQLDTVPATIDLLPEFVAAVDGSVPVLLDGGVRRGTDVVKALALGAAAVGVGRPIVWGLATAGEEGATRVLELLRDEVDHTVALCGARGLADLTPDLVRPAAGSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH45</accession>
    <name>C7QH45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4-hydroxybenzoate polyprenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8072"/>
    <dbReference type="EnsemblBacteria" id="ACU76895">
        <property type="protein sequence ID" value="ACU76895"/>
        <property type="gene ID" value="Caci_8072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8072"/>
    <dbReference type="eggNOG" id="COG0382">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034879_5_1_11"/>
    <dbReference type="OMA" id="MVVYPYG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006371">
        <property type="entry name" value="HB_polyprenyl-transferase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01475">
        <property type="entry name" value="ubiA_other"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33640" checksum="B670BB7F570C0B01" modified="2009-10-13" version="1">MSTAPVEPTGTTREVNAAPETARGVAGGTRAFLRLVLIEHSVFALPFAYISALWAMFETSGHVNWAKLALITVAMVGARTFAMAMNRIIDREIDARNPRTQMRELVTGAVSVKTAYLGSLAALVVFLAAAASLNRLSLFLAPVAVVPLVLYPYGKRFTNYPHAILGIAQAIGPMGAWIGVTGHWSWQATLLGLAVGFWIGGFDLIFACQDVAADRVIGVKSVPARFGIAASLRASIVTHVITLALLVWFGVVAHGGALWWIGVAVVAGAFWYEHSLVKPTDLSKVNRAFFTTNGFVGISLFCFALLDLIVRGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH88</accession>
    <name>C7QH88_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784322.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0072"/>
    <dbReference type="EnsemblBacteria" id="ACU69027">
        <property type="protein sequence ID" value="ACU69027"/>
        <property type="gene ID" value="Caci_0072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0072"/>
    <dbReference type="eggNOG" id="COG3640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852393_0_0_11"/>
    <dbReference type="OMA" id="GCVCPAS"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="35056" checksum="111C60E6B46F0B8D" modified="2009-10-13" version="1">MRIALVGKGGSGKTTVSALLIRHLAAGGRPVLAVDADINQHLGGALGLSEEQAAALSPMAAHLPAIKDYLRGENPLISGTEAMVKTTPPGRGSRLLRLEEENAVHSLCATRLPGDMENVRLMVTGGFEEKDLGVSCYHSKIGAAELYLNHLVDGPDEYLVMDMTAGADAFASGLFTRFDLTCLVVEPTRKSVSVYQQYREYAKEYDVTIRVVGNKVTGPDDVAYLREHTGADLVACLSASHYVRAQEQGRDKGFDTLEPANRTALARLQLEVDAVPQDWAKFTRQAVHFHLKNAHAWGDRATGVDLGAQVDPDFVMGPEAFAAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN3</accession>
    <name>C7QHN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2139"/>
    <dbReference type="EnsemblBacteria" id="ACU71058">
        <property type="protein sequence ID" value="ACU71058"/>
        <property type="gene ID" value="Caci_2139"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2139"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_764792_0_0_11"/>
    <dbReference type="OMA" id="MDWYYPV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="41322" checksum="41BCE028B8775067" modified="2009-10-13" version="1">MTVRSARSASPVEGLAAATELLACEGVLSAAQIRTTVEAIAALQRPDGAIPWFHGGHLDPWDHIEAAMALDAAGLADRALAAYRWLAASQNPDGSWYAAYADAPGGVTEPTNRLRETNFSAYIAVGVWHHWLATGDEDFLAQMWQPVQRATDFVLSLQTAGGEILWCRDEQGREADEALLTGCSSMYQALRCALAVAERLGRDRPDWELACGRLGHALTAHPERFADKGTYSMDWYYPVLGTALRGAAAEQRIAEGWDDFVVRDLGVRCVSTNPWVTGGETCELALALWAIGDTERARMLLRDIQHLRDDADGMYWTGRVFEADGAGHEPALWPVEKTTWTAGALLLALAVLAEEKATVAVFGGDGLPEGLPVACSVAECVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ0</accession>
    <name>C7QHQ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase 15-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786368.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2156"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71075">
        <property type="protein sequence ID" value="ACU71075"/>
        <property type="gene ID" value="Caci_2156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2156"/>
    <dbReference type="eggNOG" id="COG3387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010399_2_0_11"/>
    <dbReference type="OMA" id="GEPLQIM"/>
    <dbReference type="OrthoDB" id="318658at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="DUF5911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5911" evidence="2">
        <location>
            <begin position="11"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="1">
        <location>
            <begin position="242"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="624" mass="68145" checksum="BE91EA5C12C8353C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ4</accession>
    <name>C7QHQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2160"/>
    <dbReference type="EnsemblBacteria" id="ACU71079">
        <property type="protein sequence ID" value="ACU71079"/>
        <property type="gene ID" value="Caci_2160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2160"/>
    <dbReference type="eggNOG" id="ENOG50335I8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_623904_0_0_11"/>
    <dbReference type="OMA" id="LWSAPCD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="44065" checksum="1AEC04A8DC847CE0" modified="2009-10-13" version="1">MWTRQAIDAAIERRAQERSGVSAGLLELDDHPGRRLLDGAKLSGATAQAWERASAELAGLWTVFEAYQQVLDRVAAMRGGPKTRLGDRELAAMADLLTGRSVALPRQAVPFERRGLLDPASTQDLLTLDEAVQSMTRIYDVVKKVAVDAENAWNRLLEPLDDLQAKARAARATADGVGGGGGGGGADPVFDRLAGIEVQTADLRRRALSDPLGLVAGGSGTPAHVTRLLADLAGVQSELDQALTARTEFDRRLAGVQDVIVLIAQAEAEAERVRAEVREKIAAPKLPLASAAAAHLRGKVADLQRERSGQSWTLLGRNLSALEKNSRVILENAQKRVGQIRAPLDRRDELRGLLEAYRARAARHRVAETPALSAAHALARDLLWSAPCDLAGAEAAVHHYRAAVGAALPSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR4</accession>
    <name>C7QHR4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786382.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2170"/>
    <dbReference type="EnsemblBacteria" id="ACU71089">
        <property type="protein sequence ID" value="ACU71089"/>
        <property type="gene ID" value="Caci_2170"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2170"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_1_11"/>
    <dbReference type="OMA" id="GVADWMM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980990" evidence="1">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="45118" checksum="43F48FE326B391F5" modified="2009-10-13" version="1" precursor="true">MKRLALLAATGLAASLALSACSSSKSSGGSSTSDSSSKPVTITLLAPNYGSTDKDDTKLYWQKIINDFQAKYPNVKVNLEMATWDNLATKLTTALQNNDAPDLFEGGGYADVAAQGLLYKASDIVSPQTVSNLIPHVAQLGQTKGSDGQSAQYGIPFTTSTRAFFYNTTLFQQAGITSAPQTWADVAADAAKIKALGKTGYGLPLGSEEAQAETYLWTLGNGGGYKDASGKWAIDSPANVQTFQWLTDNLVKPGLTEADPGTKDRTDLWKDFAAGNIGMLNGSPALVPILKAGSIGDNWKSAAIPGKSGALTSPLGVADFIEAFNTHSDHKAAIGEFLNFALQKQYQEQFDNEYDLLPATQDAATDLSGSNPTLKPFIDALPSAAWYPSSDPNWDPASQKVKDIVGKAVSSDPKGVLDQIQAVATASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW3</accession>
    <name>C7QHW3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chorismate binding-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2219"/>
    <dbReference type="EnsemblBacteria" id="ACU71138">
        <property type="protein sequence ID" value="ACU71138"/>
        <property type="gene ID" value="Caci_2219"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2219"/>
    <dbReference type="eggNOG" id="COG0147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006493_1_0_11"/>
    <dbReference type="OMA" id="YQANLCR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="89"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="348" mass="37043" checksum="F397A50EB94CDD0F" modified="2009-10-13" version="1">MPSPARRPPPISDPEPLAHFAGRLATGLRDVTSDLSALDSSGFWAVVGTYEGDWTLARFDDVRDAPLPSPSTPWIGPDRDAWISSMDQGAYVGAVKAIRDEIAAGEVYQVNLCRVLSAPIASQAEPLALAARLRTGNPAPYAGLVNVPGTRVVTASPELFLRRDGRTVTSEPIKGTARTEEEFLPKDTAENIMIVDLVRNDLARVAEIGSVEVPALLRVEPHPGLVHLVSTVTAELTADVGWLELVAATFPAGSITGAPKSSALRIIDELENAPRGPYCGAVGWVDADRGVGELAVGIRTFWWQDDRLCFGTGAGITWGSDPQGEWDETELKAARLLAVASGPRPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHW9</accession>
    <name>C7QHW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786437.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71144">
        <property type="protein sequence ID" value="ACU71144"/>
        <property type="gene ID" value="Caci_2225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2225"/>
    <dbReference type="HOGENOM" id="CLU_1370034_0_0_11"/>
    <dbReference type="OrthoDB" id="1259001at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="20821" checksum="2492DE4A590CF56D" modified="2009-10-13" version="1">MSTISNLPHARTVPAGPTDLTERVDDLDALIWTAARTTDDPQLAVVRAREHAESVFIGLVLTIGTGAHRLNCSVPTASGPVTAGQDLRMDIATEIPAVSLPASGAERELCELFALAHVTGADATVILRSRPLLEPDADVGTPGYVVRGWRLSGGETAPIDAAGMFAFCCSEASSGEPLPLDPNTRYVDARTLVTPPGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIV1</accession>
    <name>C7QIV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8178"/>
    <dbReference type="EnsemblBacteria" id="ACU77001">
        <property type="protein sequence ID" value="ACU77001"/>
        <property type="gene ID" value="Caci_8178"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8178"/>
    <dbReference type="HOGENOM" id="CLU_3286807_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="40" mass="4207" checksum="2F4C5324C970D34D" modified="2009-10-13" version="1">MDASDRICLLSRLNALSQLPGAALARDSGAAKAMLRHGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ49</accession>
    <name>C7QJ49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0238"/>
    <dbReference type="EnsemblBacteria" id="ACU69191">
        <property type="protein sequence ID" value="ACU69191"/>
        <property type="gene ID" value="Caci_0238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0238"/>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942296_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="41"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="30915" checksum="03BB6BA3BF818025" modified="2009-10-13" version="1">MGVVMSVQPESPRKSVSLSTTVTRAPAPRPADSRGTGGTEFPYTPESVGTARHALADALQRMRVAPPAADDAVLILSELVSNALRHALPLAGGTIRVAWWMADDKVLRIAVTDGGRQQPGQAPPLKAAEAPDLVAPDLDDIDESAVDGRGLGIVGLLADAWGVEPWYAPETEATSPYLHAATTSATASAASSAATSRAIHPDPSAPKTVWAAVRLHARHAAPPPPDDQDRRWWRRMRLSLTAHLPGTTRPRTRGTRLGGSRLGEARGGPDSDAAGSDTAWVPRYPEARVGCAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ77</accession>
    <name>C7QJ77_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF397 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784514.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0266"/>
    <dbReference type="EnsemblBacteria" id="ACU69219">
        <property type="protein sequence ID" value="ACU69219"/>
        <property type="gene ID" value="Caci_0266"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0266"/>
    <dbReference type="HOGENOM" id="CLU_131550_1_0_11"/>
    <dbReference type="OMA" id="CVEVAKV"/>
    <dbReference type="OrthoDB" id="1996962at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007278">
        <property type="entry name" value="DUF397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04149">
        <property type="entry name" value="DUF397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF397" evidence="1">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7397" checksum="99A3D6CCE963E63F" modified="2009-10-13" version="1">MEIDRSKARWTKATASSGNGACVEAASVKEDEILVRNSRDPEGPKLAFTKAEWVAFLAGVKAGEFDAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJE2</accession>
    <name>C7QJE2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ctaB</name>
        <name evidence="9" type="ordered locus">Caci_2247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786458.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2247"/>
    <dbReference type="EnsemblBacteria" id="ACU71165">
        <property type="protein sequence ID" value="ACU71165"/>
        <property type="gene ID" value="Caci_2247"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2247"/>
    <dbReference type="eggNOG" id="COG0109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029631_0_1_11"/>
    <dbReference type="OMA" id="MYLKRAT"/>
    <dbReference type="OrthoDB" id="1875497at2"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU71165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="35376" checksum="BD08FF240BA13EE3" modified="2009-10-13" version="1">MEDGLLTTVETPPATAPSRTAAPSVESAAGERGGHATAVLKAYVALTKPRIIELLLVTTIPVMFLALRHVPGLWPVVAVTVGGYLSAGSANALNCYVDRDIDAEMRRTRRRPVPAASVTPQNALVFGLVLGVVSTLWLGLAVNWLSSGLALAANAFYVLVYTMVLKRRTPQNIVWGGAAGCFPALIGWTAATDRLAWAPVVLFMVVFLWTPPHFWALAIRYREDYAAANVPMLPVVAPAREVTKQIVWYSYATVACSLLLWPIGHTGLVYPIAAAVLGVVFLVEAHRLDARARSGKDGVELLPMRLFHFSNMYLALLFVAAAVSPLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG3</accession>
    <name>C7QJG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SUF system FeS assembly protein, NifU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786479.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2268"/>
    <dbReference type="EnsemblBacteria" id="ACU71186">
        <property type="protein sequence ID" value="ACU71186"/>
        <property type="gene ID" value="Caci_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2268"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_4_0_11"/>
    <dbReference type="OMA" id="MKLDSMY"/>
    <dbReference type="OrthoDB" id="1793654at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17938" checksum="2B280303E6B3F098" modified="2009-10-13" version="1">MQLESMYQEIILDHYRHPHHKGLREPFASQVHHVNPTCGDEVTMRVDLQGDVISDISYESQGCSISQASASVMADLLIGKSVGQAREVQETFLRLMQSKLEGPEFAEEHEEVLEDAVAFAGVAKYPGRVKCALLSWMAWKDATAQALADSESSVGYEGKGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK9</accession>
    <name>C7QJK9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786525.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2314"/>
    <dbReference type="EnsemblBacteria" id="ACU71232">
        <property type="protein sequence ID" value="ACU71232"/>
        <property type="gene ID" value="Caci_2314"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2314"/>
    <dbReference type="eggNOG" id="COG1585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116732_2_0_11"/>
    <dbReference type="OMA" id="AMPEFGM"/>
    <dbReference type="OrthoDB" id="1951939at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="55"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14766" checksum="74E7DE97ABB0F8DB" modified="2009-10-13" version="1">MGSMDAMVWAIVAAVLVLLELTTTTLVFVMLGIGAAAAALAAGAGGNVVVQFAAFGAVSVATLVFARPTAMKRLHGGPEHRQGIDTLIGREAFVVEKVDAHDGRVRISGEIWSARAYDGQTEYEVGDRVDVAQIEGATALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY2</accession>
    <name>C7QJY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4356"/>
    <dbReference type="EnsemblBacteria" id="ACU73220">
        <property type="protein sequence ID" value="ACU73220"/>
        <property type="gene ID" value="Caci_4356"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4356"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_0_11"/>
    <dbReference type="OMA" id="KGLWYIT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="388" mass="39141" checksum="BA90E5A27E409D04" modified="2009-10-13" version="1" precursor="true">MTTVAVLFQVWRSTGSAAWTGAIGLAQAVPLVAFGLFAGALADRLDRRRFYLACTAGQGACSALLALQALFGTFPVVGVLLVVAGQSLFGAGSGPAARTFLPQLVRTEQLGAAIALNRIAFQGSMMVGPAVGGLVVAAAGVGGCYLVDSLSFGVAFYGAFRLPRMAMRAVQAPRAGLRGVADGLSYLMHAAPVRGALLTDLATTVLTMPVSLFPLLNAERFGGNPRTLGLFLAAIAVGGVTASVFSGTFTRLPRPGAVMLLGSTVWAAALLTLGLVSNAWLGLACLGVAGAADTLAVVSRSTVVQLNTPNEMLGRVAAAEQIAGQAGPELGNLRAGLTAAATSGSVALVSGGVLCLGALALIVVKTPQLRAFTRPMTTVEPPQPVGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKB5</accession>
    <name>C7QKB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6335"/>
    <dbReference type="EnsemblBacteria" id="ACU75189">
        <property type="protein sequence ID" value="ACU75189"/>
        <property type="gene ID" value="Caci_6335"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6335"/>
    <dbReference type="HOGENOM" id="CLU_3388687_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="32" mass="3549" checksum="4FFFA89FFE3B7941" modified="2009-10-13" version="1">MTENTAVTEVEVEIYVDEATSDTAAPCDVCRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKC7</accession>
    <name>C7QKC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6347"/>
    <dbReference type="EnsemblBacteria" id="ACU75201">
        <property type="protein sequence ID" value="ACU75201"/>
        <property type="gene ID" value="Caci_6347"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6347"/>
    <dbReference type="eggNOG" id="COG4232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_873440_0_0_11"/>
    <dbReference type="OMA" id="PFPLFRQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="318" mass="34115" checksum="96C9F8EE6B00C800" modified="2009-10-13" version="1">MSAISPPVLSAPRQTSLFVNGYFPRRRVVVLVVGLLGGVLLAYLWKASLADDDIGFNTANTVLGHNAHNTPISSIASGILFAFVTGVAGSFTACNVAVFGAVGPLLGQADSRRARVLETLKPVGWMALGTMAVSAVYGFMVGLVGKHMPQYSNKKSHGLSPRALQSMIAFGTVGMVMVVCGIAALGLIRDPMAPLARRFPHAPLIVMGMLIGLFLVGRPYPLFHDMFRHAANTHNPFYGALAFALQSIGNSLVMALLFLLISVGLRGRVQRWLSENPARISILTAVAFLIAGGFNIAYWDLRVAHGLNYIWFPTAPWN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-11-02" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKH8</accession>
    <name>MSHD_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mycothiol acetyltransferase</fullName>
            <shortName evidence="1">MSH acetyltransferase</shortName>
            <ecNumber evidence="1">2.3.1.189</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mycothiol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mshD</name>
        <name type="ordered locus">Caci_8254</name>
    </gene>
    <organism>
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = CoA + H(+) + mycothiol</text>
            <dbReference type="Rhea" id="RHEA:26172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16768"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
            <dbReference type="EC" id="2.3.1.189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. MshD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.189" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796802.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C7QKH8"/>
    <dbReference type="SMR" id="C7QKH8"/>
    <dbReference type="STRING" id="479433.Caci_8254"/>
    <dbReference type="PRIDE" id="C7QKH8"/>
    <dbReference type="EnsemblBacteria" id="ACU77077">
        <property type="protein sequence ID" value="ACU77077"/>
        <property type="gene ID" value="Caci_8254"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8254"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068014_0_0_11"/>
    <dbReference type="OMA" id="AEPWFDP"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035447">
        <property type="term" value="F:mycothiol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010125">
        <property type="term" value="P:mycothiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01698">
        <property type="entry name" value="MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017813">
        <property type="entry name" value="Mycothiol_AcTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021524">
        <property type="entry name" value="MSH_acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03448">
        <property type="entry name" value="mycothiol_MshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000400243" description="Mycothiol acetyltransferase">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase 1" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase 2" evidence="1">
        <location>
            <begin position="168"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="92"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="252"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="259"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside</name>
            <dbReference type="ChEBI" id="CHEBI:58887"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01698"/>
        </source>
    </evidence>
    <sequence length="314" mass="34116" checksum="BDEED7619459A0E0" modified="2009-10-13" version="1">MTGISIGVVRRPNEADVATIRSLAEAAERADGVAPLPEQVLLHLKRSGDADADADTDAWHFVARRLSPQGSELTGYAFLDKSNAEEGPTAEVVVLPDARRQGVGGALLDALRMKVRRGDKPIRVWSHGALPAAAALAAKRGLEPVRELWVMSRPLADVPPAPTPPDGIRIATFRPGVDDEAWVEVNARAFAHHPEQGSMTVQDLRDRMAEPWFDPEGFFLAWRGAKLAGFHWTKVHDHSAYGDGPVGEVYVVGLDPAEQGHGLGRTLTEVGLRHLHDRGLGEVILYVEADNTPAVAVYTKLGFTRRSADVMYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKP3</accession>
    <name>C7QKP3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8319"/>
    <dbReference type="EnsemblBacteria" id="ACU77142">
        <property type="protein sequence ID" value="ACU77142"/>
        <property type="gene ID" value="Caci_8319"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8319"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_0_11"/>
    <dbReference type="OMA" id="PIVKDYP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="107"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="33867" checksum="71729F96A129C3A4" modified="2009-10-13" version="1">MDEIAVESPGAGESFPSTEQMLGLEPTEKPRSMFRRGLEVFLENRLAVVAFGVLVFYVVLCFLGPLVYHGNTSNVQMDEITLAPGPSHPLGTDQNGVDELGKLMKAGQISLEIGIASGVLASVIGMLYGAIAGYVGGWVDSIMMRTIDALLSIPLIFALIYIASTRGRTKMVFILVIALTSWFGLTRLTRGDTLTIKVRDYVAACRMMGGRSPRIIFRHILPNTIGTTIVNTSLSIANSVFALSVLSYIGLGLQAPNDDWGGMFANGSSYLDQNFWWMIYPPGVSIVLIIISCNFIGDALRDAFETRLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH9</accession>
    <name>C7PVH9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="journal article" date="2014" name="J. Struct. Funct. Genomics" volume="15" first="33" last="40">
            <title>Structural characterization of a hypothetical protein: a potential agent involved in trimethylamine metabolism in Catenulispora acidiphila.</title>
            <authorList>
                <person name="Filippova E.V."/>
                <person name="Luan C.H."/>
                <person name="Dunne S.F."/>
                <person name="Kiryukhina O."/>
                <person name="Minasov G."/>
                <person name="Shuvalova L."/>
                <person name="Anderson W.F."/>
            </authorList>
            <dbReference type="PubMed" id="24562475"/>
            <dbReference type="DOI" id="10.1007/s10969-014-9176-z"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS)</scope>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784630.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="PDB" id="4H3U">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.15 A"/>
        <property type="chains" value="A/B=1-134"/>
    </dbReference>
    <dbReference type="PDB" id="4HVN">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.95 A"/>
        <property type="chains" value="A/B=1-134"/>
    </dbReference>
    <dbReference type="PDBsum" id="4H3U"/>
    <dbReference type="PDBsum" id="4HVN"/>
    <dbReference type="SMR" id="C7PVH9"/>
    <dbReference type="STRING" id="479433.Caci_0382"/>
    <dbReference type="EnsemblBacteria" id="ACU69335">
        <property type="protein sequence ID" value="ACU69335"/>
        <property type="gene ID" value="Caci_0382"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0382"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107598_1_0_11"/>
    <dbReference type="OMA" id="QSCFASE"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4 5" id="KW-0002">3D-structure</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="4H3U"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="5">
        <source>
            <dbReference type="PDB" id="4HVN"/>
        </source>
    </evidence>
    <sequence length="134" mass="14256" checksum="F56F7C43D836785C" modified="2009-10-13" version="1">MTTPEIVTAWAAAWTGTNPNALGTLFAADGTYVDHAIGATMTGREQISGWKARTDAMIENVHVTITKAYRAGDHVTIEAVYGGHIKGAPTPFAVPMATLLRTRGEEITSDQDYYSLSSVLAQSGLPADWTPSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI1</accession>
    <name>C7PVI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase (Or fumarate reductase) cytochrome b subunit, b558 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784632.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0384"/>
    <dbReference type="EnsemblBacteria" id="ACU69337">
        <property type="protein sequence ID" value="ACU69337"/>
        <property type="gene ID" value="Caci_0384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0384"/>
    <dbReference type="eggNOG" id="ENOG502Z7U4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077968_1_0_11"/>
    <dbReference type="OMA" id="QHGFWSA"/>
    <dbReference type="OrthoDB" id="750409at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011138">
        <property type="entry name" value="Cytochrome_b-558"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02046">
        <property type="entry name" value="sdhC_b558_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="25936" checksum="4A0F602473EE3CC5" modified="2009-10-13" version="1">MVTATWTDRRPPSLRTAWDSSVGKKTVMAVSGLVMVLYLLAHAFGNLKVFFGPGQFDSYAHWLRTMGEPVMHYSWTLWVIRVVMVLAVVAHTVSAYQLSRRDIRARPVRYEHRKAGSSYATRTMRWGGIILGLFIIWHLLDLTTGTVHSGFQPGHPYANVVSTFNHWYGDVIYIVAVCALGLHIQHGFWSAAQTLGVGSAKRDRLIKTTGNVVAVLLTLAFVAVPVGVMSGVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT4</accession>
    <name>C7PVT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2408"/>
    <dbReference type="EnsemblBacteria" id="ACU71326">
        <property type="protein sequence ID" value="ACU71326"/>
        <property type="gene ID" value="Caci_2408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2408"/>
    <dbReference type="eggNOG" id="COG3427">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123373_0_0_11"/>
    <dbReference type="OMA" id="QVVWHEW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="17041" checksum="0AE6D971B88890BE" modified="2009-10-13" version="1">MTVTVGVPAEKAWAAIADWESQRAWMVATQVRGSADAVGGKLEGRTGIGPVAFLDTMTVTEWDPPRRCTVRHTGHVVRGSGGFEVAARGADACQVTWWERVDLPFGLLGRIGWLAIGPTTRLFFLVSLGRLKRILEAAQTTGAAKTAGAAESGEAPRQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVU6</accession>
    <name>C7PVU6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD superfamily hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786631.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2420"/>
    <dbReference type="EnsemblBacteria" id="ACU71338">
        <property type="protein sequence ID" value="ACU71338"/>
        <property type="gene ID" value="Caci_2420"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2420"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067574_0_0_11"/>
    <dbReference type="OMA" id="NEIEPAM"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="26352" checksum="E22984654372C1FE" modified="2009-10-13" version="1">MAELTAPEPTAPDRRPILVVDFDGTVYRDDSPVRFYAEHAAGSLPAEWRGRFLDLFEAYLERGIAAADRVADEAAAAVLRGSVDAWGAAAGLAALSGVAPAATEEAFLASRQYMLTAACQVTAVPALVEAIEKLRGKVRVVLATNSPAGGLAPLLERLGIGALFAEVVSGANKPEGLRRWIAAELAGREPGELFSLGDHYVNEIEPAMAVGARAGYIDRFGRADGPATVTAAVVEDILPGVFAWARALITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVX5</accession>
    <name>C7PVX5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786660.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2449"/>
    <dbReference type="EnsemblBacteria" id="ACU71367">
        <property type="protein sequence ID" value="ACU71367"/>
        <property type="gene ID" value="Caci_2449"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2449"/>
    <dbReference type="eggNOG" id="COG1690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022279_1_1_11"/>
    <dbReference type="OMA" id="QTRGVEC"/>
    <dbReference type="OrthoDB" id="1384936at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="169"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="307"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="331"/>
            <end position="334"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="402" mass="43839" checksum="B62D624B0A8AF96F" modified="2009-10-13" version="1">MYTTVPGSTEHSSPIRMWADPESVEPQALEQLRNVAALPWTRGVAVMPDVHLGIGATVGSVIAMEGAVSPAAVGVDIGCGMSAVKTTLSADQLPDDLGKLRTRIEQAIPVGRGVHHKGVRLEAVQEPGAKKPMRGWHDFWEGFDELEPSVTRGKRGRVSEQMGTLGGGNHFVEVNLDARGTVWLMLHSGSRGIGNQLAAHHIEVARTLPQNQDLRDPDLAVFLADTPQMAAYRRDLFWAQEYARRNRAVMLWLFSEVMRKEFPKIGFDKAISCHHNYVAEETYDGVDVLVTRKGAIRAAGGDLGIIPGSMGTGSYIVRGLGNDEAFNSASHGAGRRMSRTQARKQFTVEDLKQQTKGVECRKDPGVVDEIPGAYKDIRSVMAQQTDLVEIVAELKQVVCVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW00</accession>
    <name>C7PW00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2474</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2474"/>
    <dbReference type="EnsemblBacteria" id="ACU71392">
        <property type="protein sequence ID" value="ACU71392"/>
        <property type="gene ID" value="Caci_2474"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2474"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005304_0_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="363"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="721" mass="78733" checksum="AF737A3144ECCAA6" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW20</accession>
    <name>C7PW20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4404</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.40" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792997.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4404"/>
    <dbReference type="EnsemblBacteria" id="ACU73268">
        <property type="protein sequence ID" value="ACU73268"/>
        <property type="gene ID" value="Caci_4404"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4404"/>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_11"/>
    <dbReference type="OMA" id="GDACLQY"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="8">
        <location>
            <begin position="85"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="7">
        <location>
            <begin position="277"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="61036" checksum="48D99053705A8D97" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW55</accession>
    <name>C7PW55_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793032.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4439"/>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73303">
        <property type="protein sequence ID" value="ACU73303"/>
        <property type="gene ID" value="Caci_4439"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4439"/>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_370396_0_0_11"/>
    <dbReference type="OMA" id="EMASPIL"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018905">
        <property type="entry name" value="A-galactase_NEW3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10633">
        <property type="entry name" value="NPCBM_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982239" description="Alpha-galactosidase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Melibiase_C" evidence="8">
        <location>
            <begin position="352"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM_assoc" evidence="7">
        <location>
            <begin position="448"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="727" mass="76019" checksum="3016B2789577AA5C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW79</accession>
    <name>C7PW79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793056.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73327">
        <property type="protein sequence ID" value="ACU73327"/>
        <property type="gene ID" value="Caci_4464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4464"/>
    <dbReference type="HOGENOM" id="CLU_2786261_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981319" evidence="2">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="68" mass="6838" checksum="660C18605E0FA911" modified="2009-10-13" version="1" precursor="true">MATRRHPVLPTLALAAALGASALATTAAAEHAMARPDGTHTAKAFPSSHGEVGDWNTMVPEGGHPAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWL0</accession>
    <name>C7PWL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease for cytosine/purines uracil thiamine allantoin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6438"/>
    <dbReference type="EnsemblBacteria" id="ACU75290">
        <property type="protein sequence ID" value="ACU75290"/>
        <property type="gene ID" value="Caci_6438"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6438"/>
    <dbReference type="eggNOG" id="COG1457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008084_2_1_11"/>
    <dbReference type="OMA" id="FYANCGM"/>
    <dbReference type="OrthoDB" id="326558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="573" mass="60946" checksum="194DFC8B4BFCDE34" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX82</accession>
    <name>C7PX82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase 28 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784728.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0481"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69433">
        <property type="protein sequence ID" value="ACU69433"/>
        <property type="gene ID" value="Caci_0481"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0481"/>
    <dbReference type="eggNOG" id="COG1819">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_682983_0_0_11"/>
    <dbReference type="OMA" id="RWHEISE"/>
    <dbReference type="OrthoDB" id="1567639at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="292"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="419" mass="44443" checksum="F4920AB33B3A21ED" modified="2009-10-13" version="1">MTLFESPRLRVLFVAFSRSSLGHIVRSTTAAARFAADGHDVAVACHEEVRHIPEKAGLAWLPIEEIGPAPAWRGMDDPEQLRAFVRTRLASPEYVSASLEDELRVIDLFRPDVVIADMRNTAGVAASMRGVTAFTLHNLRLFQHPMHVVLPEVLVTLDQLGVEQAHARHVLGSTVLVPDIAEIDGLSDVPRDTAALICSLTDEIRHLGPLLSPELLSVAARASESESGPGPRATENRRRLLHVTLGGSGVGDQQIRRVVEAVAGLGLDIGVTLGAESLQDQVTALEDELAAVAGDSAVTVTGFRHDVVERVAAADAAVVHGGHGSIIEALVCGTPLVFLPGSLEQRENARKIRELGLGVVLAPDDDAAAVRAKVVKALSLKETPGPRRFARALVAADGAGRLVDYVTSSQAIRTAVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXE1</accession>
    <name>C7PXE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784787.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0554"/>
    <dbReference type="EnsemblBacteria" id="ACU69492">
        <property type="protein sequence ID" value="ACU69492"/>
        <property type="gene ID" value="Caci_0554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0554"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064679_0_0_11"/>
    <dbReference type="OMA" id="HDICERT"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="165"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="357" mass="40211" checksum="FFAF424427134803" modified="2009-10-13" version="1">MAVGLLYRIFVSVLSWLALLARSQASKNAEILVLRQEVSVLRRTNPKSRISWTARAVLAALSKLLPKTLRGHRIVTPGTLLRWHRRLVANKWRQPKAPGRPPISDGLVQLIVTMAQENRTWGAVRIQGELRRLGHRVAAATIRKVLRARRIPPPKHRDDSWRTFLRTQADTLLATDFFHIDCAVTLARVYVAFVIEYSTRRVHLLGITRYPTAAWAIQLARDFTADLETTGRRFTHLVRDRDAKFTAAFDAVLSAAGITAVTTMPQTPKMNAIAERFVGTVRRDCTDRILVAGERHLRVILNGYIAHYNAGRSHQGAGMSLRAPDDDPNVIPFPAQIDQIRRKRILGGLINEYEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXR3</accession>
    <name>C7PXR3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">Caci_2598</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786809.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2598"/>
    <dbReference type="EnsemblBacteria" id="ACU71516">
        <property type="protein sequence ID" value="ACU71516"/>
        <property type="gene ID" value="Caci_2598"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2598"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3033">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000035_0_0_11"/>
    <dbReference type="OMA" id="PRERWDM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="294"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="1816"/>
            <end position="1890"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="3522"/>
            <end position="3595"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="4937"/>
            <end position="5014"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="17">
        <location>
            <begin position="5688"/>
            <end position="5762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="5627"/>
            <end position="5649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="5665"/>
            <end position="5691"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="14">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="14">
        <location>
            <position position="1850"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="14">
        <location>
            <position position="3556"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="14">
        <location>
            <position position="4974"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="14">
        <location>
            <position position="5722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACU71516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="7149" mass="749801" checksum="596156167B69D056" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXR7</accession>
    <name>C7PXR7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786813.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2602"/>
    <dbReference type="EnsemblBacteria" id="ACU71520">
        <property type="protein sequence ID" value="ACU71520"/>
        <property type="gene ID" value="Caci_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2602"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_21_1_11"/>
    <dbReference type="OMA" id="MSKERIF"/>
    <dbReference type="OrthoDB" id="2072255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="83" mass="8775" checksum="217BDC532B388840" modified="2009-10-13" version="1">MADILTADDVFAVVRDTVLEVLPDLDAADIGIEGTLTDLGANSIDRADIVTMAQERLGIVVPVAQFRGVADIGALVEVLRQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV3</accession>
    <name>C7PXV3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4551"/>
    <dbReference type="EnsemblBacteria" id="ACU73413">
        <property type="protein sequence ID" value="ACU73413"/>
        <property type="gene ID" value="Caci_4551"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4551"/>
    <dbReference type="HOGENOM" id="CLU_2104576_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982299" evidence="2">
        <location>
            <begin position="46"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="115" mass="11703" checksum="CB0D1A12C91BF2C8" modified="2009-10-13" version="1" precursor="true">MRHRARRIGTLEGMRALINPRSAARLAAASVVALSLAPVSAAASAASATPSRRAPVYDLCDGHKWSLFGCRNDPALRVRQPDTGSGLVVGPAAGRQHGADAGEQCGQGGDGAEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV8</accession>
    <name>C7PXV8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4556"/>
    <dbReference type="EnsemblBacteria" id="ACU73418">
        <property type="protein sequence ID" value="ACU73418"/>
        <property type="gene ID" value="Caci_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4556"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_2_11"/>
    <dbReference type="OMA" id="QDPTTYH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="112"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="33058" checksum="166FFECD255FB50D" modified="2009-10-13" version="1">MTILTEAAAGSGPSSPPLPVPRSRGALWRRLRKDKAAATGMAIIAVMVLVALFAPLLTALEGQNTTSLHPELVDSASGGTPLGSLGGISASHWFGVEPQTGRDLFARLVYGARISLGVALGATVLQVLIGVSVGIAAGLGGRATDAVLSRLTDLTLAFPSVLFAIGLMAIVPGSVPRPLILAVVIAVLGWGSTARLARGQALSLRTRDYVAAAKLSGAPPLRVARREILPGLVTPILTYAALLVPTNMISEAGLSFLGVGVRPPTPSWGQMLSAGTTWFRPDVMYVLVPGGALFLTLLAFTLLADGVRRTLDPRNTEVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY08</accession>
    <name>C7PY08_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793197.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4607"/>
    <dbReference type="EnsemblBacteria" id="ACU73468">
        <property type="protein sequence ID" value="ACU73468"/>
        <property type="gene ID" value="Caci_4607"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4607"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1287934_0_0_11"/>
    <dbReference type="OMA" id="QLIRTGP"/>
    <dbReference type="OrthoDB" id="1914615at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017519">
        <property type="entry name" value="CHP03085"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03085">
        <property type="entry name" value="TIGR03085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="22428" checksum="2A1C9D8F2E451E82" modified="2009-10-13" version="1">MGTHARAERAHLAQVLTDAGPDAPTLCQGWTTRDLAAHVVVRERRLDAAGGIMMKALAPRLARVQAEFAARPWPELVEMVAAGPSKRSLLGVAAVDEAANVVEFFVHCEDVRRAKPGWEPRVLDPELAEVLWKRASGMAKLVGRRAPAGLVLRRPDGQTAVAHKGAPVVTVTADPGELVMFMSGRQGHSVVEMEGPEQAVAAVRGAKFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY09</accession>
    <name>C7PY09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III Xth</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4608"/>
    <dbReference type="EnsemblBacteria" id="ACU73469">
        <property type="protein sequence ID" value="ACU73469"/>
        <property type="gene ID" value="Caci_4608"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4608"/>
    <dbReference type="eggNOG" id="COG0708">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027539_0_2_11"/>
    <dbReference type="OMA" id="YEVAHVG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="28730" checksum="DC6AE9C85CDC9E81" modified="2009-10-13" version="1">MVVRVATWNVNSVTARVERLVGWLDSAKPDVVCLQELKTTDEAFPAGQLADVGYQAATWGTGRWNGVAILSRLPIADVWRGWPDLPDFDGVAEPRALTATCGGVRVTCVYVPNGRELGHPHFDYKLRWLDSLTASVAEPARGELPYAVLGDFNIAPTDADVWDMSLFAESTHVTPAERAKLADLEAQGLVEVLPRALKYDKPYTYWDYRQLAFPKNNGMRIDLVFGNAAFAGAVRDAYVDREERKGKGASDHAPVVVDLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYV2</accession>
    <name>C7PYV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0571"/>
    <dbReference type="EnsemblBacteria" id="ACU69508">
        <property type="protein sequence ID" value="ACU69508"/>
        <property type="gene ID" value="Caci_0571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0571"/>
    <dbReference type="eggNOG" id="COG3254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100689_3_0_11"/>
    <dbReference type="OMA" id="TSWTIWR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016857">
        <property type="term" value="F:racemase and epimerase activity, acting on carbohydrates and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008000">
        <property type="entry name" value="Rham/fucose_mutarotase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05336">
        <property type="entry name" value="rhaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="12100" checksum="D2C8BCE9F5698148" modified="2009-10-13" version="1">MRGVLVRVAIHTRLKPEGVTGYEQAHDDIPPEIPELLRAGGCTAWTIWRNGVDLFHLVECEDWEALRAFLADKDDDRAWQARVGVFRDFSLVGGDQPLPMIFELPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE1</accession>
    <name>C7PZE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulatory protein DeoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2682</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786891.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2682"/>
    <dbReference type="EnsemblBacteria" id="ACU71598">
        <property type="protein sequence ID" value="ACU71598"/>
        <property type="gene ID" value="Caci_2682"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2682"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_15_0_11"/>
    <dbReference type="OMA" id="FESSKFA"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="378" mass="39949" checksum="9B18799F911CFD66" modified="2009-10-13" version="1">MLAHQRYSYVLDQLRTHGAIKVTDVVAGLGVSDGTVRRDLEVLEEQGKLVRVRGGAVLPGPLHSGGPPSADPRSQDPATTEGVVLGMLVPSTTYYYPEVIRGAQTVVSRAGARLILGVTDYDGDRDLEQLRDLIRSGCRGLMVTTATGPVIPAPVRGLLEDCALPFVLVERRSAETFDDVDYVLSDHRQGAYRAVEHLAALGHRSVALFVHATPTARLVADGYAEGVRLLGLDTDAPVHAPAAGADRQAELDAFAKACRDSDATAALVHSDREAILLAQRLRAQGVRIPEDLAVIAYDDEVAAFAEVPLTAVAPPKFEVGRSAASALLEQIAATGPLPVRQTVLQPRFVVRDSTRRGATSTQTAAGAADPDAASPVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZR2</accession>
    <name>C7PZR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4716</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4716"/>
    <dbReference type="EnsemblBacteria" id="ACU73577">
        <property type="protein sequence ID" value="ACU73577"/>
        <property type="gene ID" value="Caci_4716"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4716"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="HEPPLLN"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="36481" checksum="EF8DF3DAE7854370" modified="2009-10-13" version="1">MTRERVRAGETVRGGGRPGLRDVAELAGVSHQTVSRVFKDHPRVSAETRAKVLAAAAQLDFRPNAIARALATGSSRTIGVVSFDTTLFGPASMVSAIESSARDADYFVSVVGLASPSRRSVAEAADRMRGQGVDGIILIPGHVPADQVVRHLPAMLPVVSLSAAETVASASVDQYDGPLAAVRHLLDLGHRTVHHVAGPADWLDARQREQAWRDALTAAGAPVPEPLPGDWSAASGYERGQVLAADPRVSAVFAANDHIALGVLLALHEARRRVPEEVSVIGFDDIPEAAFFTPPLTTVRQDFSALGRRSMALLLDQIGASAPAASPVAAVIPTELVVRRSTARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q150</accession>
    <name>C7Q150_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2815"/>
    <dbReference type="EnsemblBacteria" id="ACU71725">
        <property type="protein sequence ID" value="ACU71725"/>
        <property type="gene ID" value="Caci_2815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2815"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126038_0_0_11"/>
    <dbReference type="OMA" id="DCVMLEL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="161" mass="18205" checksum="4E63DCAFFC94FE80" modified="2009-10-13" version="1">MPDRERLSRSSFRRIQPISQPRPLTLLPQRIWSADNWDRLQAGYRAGDMEEKWNVFAEDNVVFMHRSWTGLGMYEVTFNPADGDGCRITQAVVEGDAERNRPEDDEFDCVMLELVLSAIVLGEPAQQARERLVALRRRTADGANLPAGALLHSVVGLRSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1L8</accession>
    <name>C7Q1L8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoadipate enol-lactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793476.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4887"/>
    <dbReference type="ESTHER" id="catad-c7q1l8">
        <property type="family name" value="Carboxymethylbutenolide_lactonase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73747">
        <property type="protein sequence ID" value="ACU73747"/>
        <property type="gene ID" value="Caci_4887"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4887"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_54_1_11"/>
    <dbReference type="OMA" id="AYAACCD"/>
    <dbReference type="OrthoDB" id="1792151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047570">
        <property type="term" value="F:3-oxoadipate enol-lactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042952">
        <property type="term" value="P:beta-ketoadipate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012788">
        <property type="entry name" value="Decarb_PcaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026968">
        <property type="entry name" value="PcaD/CatD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02425">
        <property type="entry name" value="decarb_PcaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02427">
        <property type="entry name" value="protocat_pcaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="CMD" evidence="2">
        <location>
            <begin position="293"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="41918" checksum="0CC89F3B4C53DE1A" modified="2009-10-13" version="1">MSLVPHFVIEGPSDAPPLLLAPSLGTSLAVWDGHVKALARDHRVIRWDLPGHGGSAATLVGERATVAELADLVLALADHLGLERFAYAGISIGGAVGAHLAVRHPDRITSLALVCSSAHFGEPQAWLERAARVRREGTEFLAASAPARWFTSDFPGGEALEKLISDQRAADPVAYAACCEALADCDLRGELDRITAPTLVIAGREDTATPPPHSRELADGIAGAGLLEIPGAGHLAPVERPRPVLDALRAHFGAAPSDDAERHAAGTAMRRAVLGDAHVDRALAAATPLTAGFQDFITRYAWGEIWTRPGLDRRTRSCVTLTALVAGGHHEELALHVRAAVRNGLTPEEIGEVLLQTAVYCGVPAANAAFAIARRVLDEATSDETTADETTDHKDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q248</accession>
    <name>C7Q248_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797309.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8770"/>
    <dbReference type="EnsemblBacteria" id="ACU77585">
        <property type="protein sequence ID" value="ACU77585"/>
        <property type="gene ID" value="Caci_8770"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8770"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_7_0_11"/>
    <dbReference type="OMA" id="MQFWSGT"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019921">
        <property type="entry name" value="Lucif-like_OxRdtase_Rv2161c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03619">
        <property type="entry name" value="F420_Rv2161c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="32371" checksum="A2296B13F5818D6E" modified="2009-10-13" version="1">MKFWLSPAFCDTAHLTGLARAAEEYGFEGIAIPDHLFHPVELSSPYPYTPDGSRYWSKDTHWPEPWVAIAAMAAVTTRLRFTTNIYVAPARDLLTVANQLATAAYLSQGAPDGHHRVALGVGPGWSKDEFIATGQAFSRRGARLDEMLIALRQLWTGDVVEVSGPNYTLPACSITPTPNDPIPVYVGGISDIAIRRAAQNDGWIGIYHTVDETHSIMDRLRTAREQAGTLDRPFRAMLAVLAEPTPDLCEQLEEWGVTDLLGAPWMTNIKAMTAPGPSLAEMVEAMEGFAGRYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M9</accession>
    <name>C7Q2M9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ordered locus">Caci_0939</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785166.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0939"/>
    <dbReference type="EnsemblBacteria" id="ACU69871">
        <property type="protein sequence ID" value="ACU69871"/>
        <property type="gene ID" value="Caci_0939"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0939"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158491_3_3_11"/>
    <dbReference type="OMA" id="RFQMATS"/>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="8488" checksum="0B9C7CDCC781C385" modified="2009-10-13" version="1">MATGTTARELRELGDAELLEKLRESKEELFNLRFQQATGQLENHGRMRAVKKDIARIYTLMTERELGIGHSEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2R5</accession>
    <name>C7Q2R5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2898"/>
    <dbReference type="EnsemblBacteria" id="ACU71807">
        <property type="protein sequence ID" value="ACU71807"/>
        <property type="gene ID" value="Caci_2898"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2898"/>
    <dbReference type="HOGENOM" id="CLU_2068874_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="13272" checksum="CCB353355F930D2A" modified="2009-10-13" version="1">MAVTAPRRYVGLMSAEPSDATPHRISLPRTIRAIKQALTAEQRNQFMAELEDIEAGSLRATVEKWWLTAVMNRAGTWGRVEQVKAGTARTVPIEDVIPDFAEQFEQRHGRPYVGHSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2T7</accession>
    <name>C7Q2T7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2920"/>
    <dbReference type="EnsemblBacteria" id="ACU71829">
        <property type="protein sequence ID" value="ACU71829"/>
        <property type="gene ID" value="Caci_2920"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2920"/>
    <dbReference type="eggNOG" id="ENOG502ZGR4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1248781_0_0_11"/>
    <dbReference type="OrthoDB" id="2085755at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="24339" checksum="A6C025245B558645" modified="2009-10-13" version="1">MEPAVTVESRPRWGKAGVRLTEQEAATIDFRNACRATEAAERAERDKDAAYGSWKAGRLRPYLITYALDRHGLYGPRVDVACGTEEPAADEWEAGVRYPTWPEFKALAALTLYPLGHFLRDANPIPFESTSMRFHLKPGMKPPPEPILCFEPEAIWAATRTPRCPWCCRGVQTVMPECLFCPHCGAAQMDGEAVRTVGGEGFAQCPDCGGRWPAETAAVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2X0</accession>
    <name>C7Q2X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787155.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71862">
        <property type="protein sequence ID" value="ACU71862"/>
        <property type="gene ID" value="Caci_2953"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2953"/>
    <dbReference type="HOGENOM" id="CLU_2599574_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8549" checksum="437F74C6ABFCAD55" modified="2009-10-13" version="1">MYGYVPEDLDNQVPSEGSDDASWLDDSSEPVSAGFEWVIEGGPEILTAGLPPWTGETWGNGTDRWAHLEAGWNSKPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q367</accession>
    <name>C7Q367_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793532.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4943"/>
    <dbReference type="EnsemblBacteria" id="ACU73803">
        <property type="protein sequence ID" value="ACU73803"/>
        <property type="gene ID" value="Caci_4943"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4943"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="MHRRDPA"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="21"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35668" checksum="925173CAD277AA05" modified="2009-10-13" version="1">MSPSIPTVRLGSDGPAVGAQGLGCMGMSEFYGDTDQDSARQTLEAALSAGVTLFDTADMYGRGENERFLAPFLRAHRDHVVIATKFGSVRAADGPMSVSNDPAHIRRAVEASLTRLGIEVIDLYYMHRRDPAVPLADSVGAMADLVHAGKVRHLGLSEVTADELREAHSHHPISAVQAEWSLFTRDIERSLVPAAAELGVGVVAYSPLGRGFLTGAVPSTLAADDVRTRFPRFTGENAERNAALLPPITSIAAARGATPAQVALAWLHQRRATHRLPVVPIPGTRHPHRLKENLAALELTLTAEELARLEPLAAHVAGDRYPDMAETSNAREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S3</accession>
    <name>C7Q3S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8868"/>
    <dbReference type="EnsemblBacteria" id="ACU77681">
        <property type="protein sequence ID" value="ACU77681"/>
        <property type="gene ID" value="Caci_8868"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8868"/>
    <dbReference type="eggNOG" id="ENOG5032QY7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123911_0_0_11"/>
    <dbReference type="OMA" id="ITWTFPD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="15991" checksum="99C8D94595CDEEBB" modified="2009-10-13" version="1">MIEQLGAAHAKAWGLGTADRWDLDQRTGLITWTFPDKTATAPAQILGSFHAEAESWLWAWANDSILPEMSRDAWAVHVWGEAHGHRALTEPKVRGDASTAGALVALAVRITRATGYYKGGDGGAIPIITFGPVTLASRDGATRTVTVEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q482</accession>
    <name>C7Q482_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1014</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1014"/>
    <dbReference type="EnsemblBacteria" id="ACU69942">
        <property type="protein sequence ID" value="ACU69942"/>
        <property type="gene ID" value="Caci_1014"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1014"/>
    <dbReference type="eggNOG" id="COG0578">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_5_1_11"/>
    <dbReference type="OMA" id="TFCGVRV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="8">
        <location>
            <begin position="7"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="9">
        <location>
            <begin position="387"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="552" mass="59655" checksum="73E4F27CF27783AB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B0</accession>
    <name>C7Q4B0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785264.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1044"/>
    <dbReference type="EnsemblBacteria" id="ACU69970">
        <property type="protein sequence ID" value="ACU69970"/>
        <property type="gene ID" value="Caci_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1044"/>
    <dbReference type="eggNOG" id="COG0300">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_6_11"/>
    <dbReference type="OMA" id="AWIFATC"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24106" checksum="B7AAEF2F1E00B033" modified="2009-10-13" version="1">MQLTHATALVTGANRGLGRHLAQQLRDSGAHVYAAARNPASIDLEGVTPLALDVTDPASVAAAAKTATGVSILVNNAGVATFASLLDGDVEDIHREFDTNFFGTLAVTRAFAPQLGAHDESYVLNILSVLSWVSMPHLGGYSASKSAQWSLTNALRQELAGQGTKVGGLHVGYMDTDMAAAVEDSKLDPADVTRRALEAIKAGETEIVIDELSRNVRAGLSGGVAALYPSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4C8</accession>
    <name>C7Q4C8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785282.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1062"/>
    <dbReference type="EnsemblBacteria" id="ACU69988">
        <property type="protein sequence ID" value="ACU69988"/>
        <property type="gene ID" value="Caci_1062"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1062"/>
    <dbReference type="HOGENOM" id="CLU_074078_3_0_11"/>
    <dbReference type="OMA" id="MQSEHVR"/>
    <dbReference type="OrthoDB" id="1635544at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007995">
        <property type="entry name" value="DUF742"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36221">
        <property type="entry name" value="PTHR36221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05331">
        <property type="entry name" value="DUF742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="13654" checksum="4B1386CD6A203E93" modified="2009-10-13" version="1">MGRVQDAGTPWDEDDDIDRLRLYSLTGGRTVPTRSLDLASLVHVASGDPPQMDGEHAQIHALCRVEARSIAELAGLLRQPATVVKILVCDLLDAGALSHATPDFESDPTDLKLLERVLAGLREISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4D4</accession>
    <name>C7Q4D4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785288.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1068"/>
    <dbReference type="EnsemblBacteria" id="ACU69994">
        <property type="protein sequence ID" value="ACU69994"/>
        <property type="gene ID" value="Caci_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1068"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_2_11"/>
    <dbReference type="OMA" id="RRTYDEW"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="19499" checksum="2AC71DBD0A28601C" modified="2009-10-13" version="1">MRKLVSTLFLSLDGVAEDADKFIVGWDDVVDAHGEAIIATQDAVILGRRSYDEWSAFWPGSEIEPFATFINTVPKYVATSTPLESEWHNTTVIDGDLVEFVQDLKNSAGEDIGVHASIRLNQALLAAGVVDELRLAIAPVVAGHGRRLLDGLPQMRFETIRSVTTPSGYVLADYRTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4J5</accession>
    <name>C7Q4J5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787257.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3055"/>
    <dbReference type="EnsemblBacteria" id="ACU71964">
        <property type="protein sequence ID" value="ACU71964"/>
        <property type="gene ID" value="Caci_3055"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3055"/>
    <dbReference type="HOGENOM" id="CLU_2245072_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="11292" checksum="7B334950AAF638C0" modified="2009-10-13" version="1">MSIDAAPSADIEMARVLHAALGMYLASNGLGPDLEPLLYSIEEAAERLGLESTNQLYRRTSDGTWPYTLIGGLKKFSKANLEQIIKIQAREAVSKASRDALRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q563</accession>
    <name>C7Q563_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7002</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795560.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7002"/>
    <dbReference type="EnsemblBacteria" id="ACU75832">
        <property type="protein sequence ID" value="ACU75832"/>
        <property type="gene ID" value="Caci_7002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7002"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_35_5_11"/>
    <dbReference type="OMA" id="WIDNIER"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033068">
        <property type="term" value="P:macrolide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015083">
        <property type="entry name" value="Polyketide_synth_docking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036299">
        <property type="entry name" value="Polyketide_synth_docking_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08990">
        <property type="entry name" value="Docking"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101173">
        <property type="entry name" value="SSF101173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1669"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1820" mass="189745" checksum="2338CD58D3F018FA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q576</accession>
    <name>C7Q576_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7015"/>
    <dbReference type="EnsemblBacteria" id="ACU75845">
        <property type="protein sequence ID" value="ACU75845"/>
        <property type="gene ID" value="Caci_7015"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7015"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_10_2_11"/>
    <dbReference type="OMA" id="WETVEGM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9195" checksum="A1A0C00DFC5533C6" modified="2009-10-13" version="1">MTSQETEIPLPFQELLRPHLPYAGAGPLGAGEDLAALGLDSMAVVQLLSDVEAEFGVELPDEILDEATFATVGSLWAAVSALVGSGADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5E5</accession>
    <name>C7Q5E5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tricorn protease homolog</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_7084</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades oligopeptides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S41B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795642.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7084"/>
    <dbReference type="EnsemblBacteria" id="ACU75914">
        <property type="protein sequence ID" value="ACU75914"/>
        <property type="gene ID" value="Caci_7084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7084"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005503_1_0_11"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028204">
        <property type="entry name" value="Tricorn_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029414">
        <property type="entry name" value="Tricorn_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012393">
        <property type="entry name" value="Tricorn_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43253">
        <property type="entry name" value="PTHR43253"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14684">
        <property type="entry name" value="Tricorn_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14685">
        <property type="entry name" value="Tricorn_PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036421">
        <property type="entry name" value="Tricorn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="TSPc" evidence="11">
        <location>
            <begin position="873"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="541"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="555"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="775"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="996"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="1054"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer; via amide nitrogen" evidence="9">
        <location>
            <position position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036421-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036421-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU75914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1107" mass="119516" checksum="7ECB1F6DE06469E1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5N0</accession>
    <name>C7Q5N0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein Caci_9028</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_9028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9028"/>
    <dbReference type="EnsemblBacteria" id="ACU77841">
        <property type="protein sequence ID" value="ACU77841"/>
        <property type="gene ID" value="Caci_9028"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9028"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140930_4_0_11"/>
    <dbReference type="OMA" id="MGNMMKQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="12683" checksum="4605434308D6514A" modified="2009-10-13" version="1">MAFPDETGPGGGMPDLGGMDLQGMLGQAMQMQQRMVEAQQELERTIVSGSAGGGLVTAKVTGTGDLVGLDIKPEAADPEDTETLADLVIAAVRDARAAADKLAADKMGPLAGGGMPDLGNLGNLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W9</accession>
    <name>C7Q5W9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785360.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1140"/>
    <dbReference type="EnsemblBacteria" id="ACU70066">
        <property type="protein sequence ID" value="ACU70066"/>
        <property type="gene ID" value="Caci_1140"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1140"/>
    <dbReference type="HOGENOM" id="CLU_2192279_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="12151" checksum="43D74B82075BF4CA" modified="2009-10-13" version="1">MGVGGWLRKSTDRFLSRFEDPLEQFELARRRQLDLLGDLEHRLLLVQPGSDEEANLLKAKGDLQGRISEFQGIIARLKASQSAGASASAADRLEEEMQRLAEDARRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Y2</accession>
    <name>C7Q5Y2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785373.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1153"/>
    <dbReference type="EnsemblBacteria" id="ACU70079">
        <property type="protein sequence ID" value="ACU70079"/>
        <property type="gene ID" value="Caci_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1153"/>
    <dbReference type="eggNOG" id="ENOG50334HZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1616460_0_0_11"/>
    <dbReference type="OrthoDB" id="1798618at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="20070" checksum="C578AFE92E73621E" modified="2009-10-13" version="1">MGYTTEFTGAVTVEPPLNTHEISYLRRFVGTRRMDRELGPYYCGTGHMGQDEEPDIRDYDKAGFGQPGLWCKWEPTDDGSRIRWNQAEKFYNSEEWMAYLIRTFLMPGAALAAELASRVEGHYYAPEFAHFTFDHVVNGAIDADGEEVDDLWQLVVTDNEVTTRDMGPGPIYVDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6H7</accession>
    <name>C7Q6H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793741.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5153"/>
    <dbReference type="EnsemblBacteria" id="ACU74012">
        <property type="protein sequence ID" value="ACU74012"/>
        <property type="gene ID" value="Caci_5153"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5153"/>
    <dbReference type="eggNOG" id="COG3173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074977_0_0_11"/>
    <dbReference type="OMA" id="NTMYRLG"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="35"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="33087" checksum="FFE35F4926EF3BBE" modified="2009-10-13" version="1">MHDDQLTVSEDIVRGLVDEQFPQWRELPVTQLASQGTVNAIFRIGDRLAARLPLKPGPPATIRRELEAEAEASRELAGSTRFPTPEPVALGEPGAGYPAPWSVQTWLPGATATEEDPHASIPFAHDLAEFIGGVRALDTRGRVFGGKGRGGDLRAHDAWMDTCFERSEHLLDVPRLRDLWAVLRDLPRTDPDRMTHGDLIPGNVLVADGRLTGVLDAGGLAAADPALDLVAAWHLLDAEPRRALRETLACDDLQWQRGKAWAFQQAMGVVWYYLDTNPAMSRMGRRSLDRILGDADDLADGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6L3</accession>
    <name>C7Q6L3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DSBA oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5189"/>
    <dbReference type="EnsemblBacteria" id="ACU74048">
        <property type="protein sequence ID" value="ACU74048"/>
        <property type="gene ID" value="Caci_5189"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5189"/>
    <dbReference type="eggNOG" id="COG3071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073599_0_0_11"/>
    <dbReference type="OMA" id="DVVCPWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="265" mass="28259" checksum="D409F6DBE8667418" modified="2009-10-13" version="1">MWADVANPWTFVAAERLRVALAVADVAAEVVWRPLLTDAADPDAPRDALRLLLLAEERGGAELQGRVAAELLASHDVRDAGELAAIADRAGFPEGGALLASEDSADAGRARLRELLLIGKARGISVSPTLAIGDRLLEFAMSPATIGEFLVEPADGARGLPAEVQRLRWVEELMALSDPLGALVVLEPLLAEHGQDPNIRRVAASAYFASAQLGRARQVLEATLADYAADSYARLMLGRTLERQGRGAEAEKHLRMAAAMTPEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6N8</accession>
    <name>C7Q6N8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="8" type="ordered locus">Caci_5214</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793802.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5214"/>
    <dbReference type="EnsemblBacteria" id="ACU74073">
        <property type="protein sequence ID" value="ACU74073"/>
        <property type="gene ID" value="Caci_5214"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5214"/>
    <dbReference type="eggNOG" id="COG0171">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025662_0_0_11"/>
    <dbReference type="OMA" id="RLAQDCY"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041856">
        <property type="entry name" value="NAD+_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="7">
        <location>
            <begin position="12"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="367"/>
            <end position="374"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="491"/>
            <end position="494"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="634"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="680" mass="74356" checksum="7FB02933ACBA07E1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P0</accession>
    <name>C7Q6P0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793804.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5216"/>
    <dbReference type="EnsemblBacteria" id="ACU74075">
        <property type="protein sequence ID" value="ACU74075"/>
        <property type="gene ID" value="Caci_5216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5216"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_1_11"/>
    <dbReference type="OMA" id="FFPKPMA"/>
    <dbReference type="OrthoDB" id="1919329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16539" checksum="4C8401A6DB4B5A9C" modified="2009-10-13" version="1">MAAKRQASADACPVMRTVDLVGDRWTLLILRDAFDGPARFSQLQRSLGIAKNILSDRLGGLVEAGILRTAPAADTSAYQAYALTDKGRDLFNVIIALRQWGEQYAFDPGEDYRPLIDQTTGEPLPHLTYARPDGSPVRPSETALGEVRPIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6U7</accession>
    <name>C7Q6U7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tannase</fullName>
            <ecNumber evidence="7">3.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.20" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795688.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="SMR" id="C7Q6U7"/>
    <dbReference type="STRING" id="479433.Caci_7130"/>
    <dbReference type="EnsemblBacteria" id="ACU75960">
        <property type="protein sequence ID" value="ACU75960"/>
        <property type="gene ID" value="Caci_7130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7130"/>
    <dbReference type="eggNOG" id="COG1506">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_3_2_11"/>
    <dbReference type="OMA" id="LTPMAKN"/>
    <dbReference type="OrthoDB" id="865015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050318">
        <property type="term" value="F:tannase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="PTHR33938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980646" evidence="6">
        <location>
            <begin position="30"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="555" mass="58242" checksum="D1B7155682C53861" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q754</accession>
    <name>C7Q754_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ordered locus">Caci_1217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785436.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1217"/>
    <dbReference type="EnsemblBacteria" id="ACU70142">
        <property type="protein sequence ID" value="ACU70142"/>
        <property type="gene ID" value="Caci_1217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1217"/>
    <dbReference type="eggNOG" id="COG0224">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050669_0_0_11"/>
    <dbReference type="OMA" id="MQITSAM"/>
    <dbReference type="OrthoDB" id="1701531at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="304" mass="33233" checksum="F5ECCC5E2F476FB5" modified="2009-10-13" version="1">MGGQLRVYRRRIASVKATKQITRAQELIATARIVKAQQKVAASTPYAEEITRAVSAVASRSNASHALTTEREPQAGVRPKAAVLVVTSDRGFCGGYNTNTLKEAEQLMQLLREQGKEPVRYVVGRKGVSYNSFRERSMAGSWVGFSDNPAYTDARTVADEVIEAFLAEEGGMDEIHLVSTRFISMLSQQPTTVRILPLQYEETTETPAGGVFPLYEFEPSPERVLDALLPHYVRARIYNAMLQSAASEHAARRRAMKSATDNASDLIDNLTRQANAARQAEITQEISEIVGGANALADANVGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7N6</accession>
    <name>C7Q7N6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787522.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3322"/>
    <dbReference type="EnsemblBacteria" id="ACU72229">
        <property type="protein sequence ID" value="ACU72229"/>
        <property type="gene ID" value="Caci_3322"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3322"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_7_0_11"/>
    <dbReference type="OMA" id="DERITAC"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="187"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="49143" checksum="185C23FCE8C801D2" modified="2009-10-13" version="1">MYTVFRPELDDLAREILARYRAYQEGRTTPAELDAYRLACFAATLGYAKQHSPLYRERLAHVDPEKISTLTPEALAEIPFTTKEDLRDHGFDLASLPVHQAWVYYETTGTTGASTPSPRADVDSLNTNIAMTVQYEPLLRNFGTQQVMGVCGPSELHAHGDTFTEVCRNLGYASIKMWPYSPMIGFERALRVMRELPVTGLFCTPGMAVALAKAAVAAGADPRKDFSVNVLMLTGETAPPGLLAHIGELWDAEAHMSLYGSQESSVLALGSAQGHLQLTPLLNYYEVVDPLTLKPATPDAQGVLRGEMVATHLYQGAKPLVRYRTGDRVRLHADGRIEVLGRVADRLVLNGVETTAYDLEDAVIAGVTRYLDHKILIDHRNGRDTLALILTPEHEDNHPQHLDERITACRKAFDAELEIIVADAETVAAPTGPVSWKTPRIHDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7P1</accession>
    <name>C7Q7P1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3327</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787527.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3327"/>
    <dbReference type="EnsemblBacteria" id="ACU72234">
        <property type="protein sequence ID" value="ACU72234"/>
        <property type="gene ID" value="Caci_3327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3327"/>
    <dbReference type="eggNOG" id="COG3861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324449_0_0_11"/>
    <dbReference type="OrthoDB" id="1779215at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="23893" checksum="7A0C4FFAEFB2DABA" modified="2009-10-13" version="1">MNAFEEYDIGSAVRCHTGPCGHLVCVVVDPVAERLTHLIVVARDGTAGRLVPVELAHADQDGVRLDCTQEHFDRLEPSIATHFLLAPDAEQRYGYHEGEVVYWPFYGLAPAGAAMGLTCLDPLASPRMEIEDRVPAGQVRIRRGERVEASDGPIGHVRGLVVDPADEAVTHVLLDEGHLWGHKRVAIPVGAVTGIDAEGVTVRLTKHQIKDLPSVEVAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q806</accession>
    <name>C7Q806_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793902.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5314"/>
    <dbReference type="EnsemblBacteria" id="ACU74173">
        <property type="protein sequence ID" value="ACU74173"/>
        <property type="gene ID" value="Caci_5314"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5314"/>
    <dbReference type="eggNOG" id="COG0241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032560_0_0_11"/>
    <dbReference type="OrthoDB" id="626964at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="646" mass="67117" checksum="4AD0B1244BF0859B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q811</accession>
    <name>C7Q811_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lnt</name>
        <name evidence="11" type="ordered locus">Caci_5319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5319"/>
    <dbReference type="EnsemblBacteria" id="ACU74178">
        <property type="protein sequence ID" value="ACU74178"/>
        <property type="gene ID" value="Caci_5319"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5319"/>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019563_0_1_11"/>
    <dbReference type="OMA" id="IPQSMKW"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="228"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="533"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="566" mass="60573" checksum="3E93FBFD85192ED7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8H2</accession>
    <name>C7Q8H2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7331"/>
    <dbReference type="EnsemblBacteria" id="ACU76160">
        <property type="protein sequence ID" value="ACU76160"/>
        <property type="gene ID" value="Caci_7331"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7331"/>
    <dbReference type="eggNOG" id="ENOG50328GS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067990_0_0_11"/>
    <dbReference type="OMA" id="TKCREYE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025855">
        <property type="entry name" value="Replic_Relax"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13814">
        <property type="entry name" value="Replic_Relax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="34140" checksum="5904108D61134800" modified="2009-10-13" version="1">MTADLTPTDRPTGRAEWATTRPADTGGRHRRNSSMSGGVTSSRRAPAERLADRLGPRDLAVLASLNEFRLLSGSQLRRLHCPGGEISTQARKTRAIMRRLTELGVVARAERGVGGIRSGSEGYVFGLSGLGHAVLDRDQPGARRHRSAIESKSTFTAHILACSELMCQLVEHSRAGGCTIEELRAEPGCWRWFSSQSGGRRPLKPDAYVRLTVDDFDLAAFIEIDLATESLPTIASKCAVYLDYWRSGAEQRVAGFFPRVWWLVPHPDRAGAISRTIQRLAPAEQRLFAVALIEDAVAALTTTPHTDTKGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L3</accession>
    <name>C7Q8L3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine synthase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1355"/>
    <dbReference type="EnsemblBacteria" id="ACU70278">
        <property type="protein sequence ID" value="ACU70278"/>
        <property type="gene ID" value="Caci_1355"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1355"/>
    <dbReference type="eggNOG" id="COG0421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068637_2_0_11"/>
    <dbReference type="OMA" id="LSFEYQR"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="332" mass="36355" checksum="0AE981CB251DC7F8" modified="2009-10-13" version="1">MTATAEPVESVIAGLDAWYRKVPLSSGAPPHDLATAVHGQRTPRLSSMSRAKTPPDPPADLPENDDWELLRDLDRRNAYQLLVGGTPHSHVDLDDPTYLEYEYVRQIAHLVDLAAEERAPMRVLHLGGGGLTLPRYIAVTRPGSGQQVVEIEGRLLDFVRKALPLPRNARVRLRTGDARDVLGRVPEGAFDLTVTDVFAAARIPKHFTSTEYVALSKRALRPTGAHVVNLADGTARSGLTFTRRQVATAKQHFEHVLLLADPGILRGRKYGNLVLMASNAPLPVAELIRRAASDPFPSRVVRGQDLDDFQGGAKPMTDEDCEQSPEPPDDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9G3</accession>
    <name>C7Q9G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794038.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5450"/>
    <dbReference type="EnsemblBacteria" id="ACU74309">
        <property type="protein sequence ID" value="ACU74309"/>
        <property type="gene ID" value="Caci_5450"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5450"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="MRDEIMD"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="26642" checksum="72B1D2DDD3852761" modified="2009-10-13" version="1">MYEISGLTKTYKRGKDTVEALRGVDVVIPDGDLLAIQGPTGHGKSTLLQLIGGLDRPTGGRLVFNGRDMAGMNETQLTKLRARHFGYIFQSFNLIPTLTAQENVETALVPLGVSATERRERAARALADVGLDERRSHLPAELSGGQQQRVAIARALVKEPEVIMADEPTGNLDEETRDEIFALLQSLWRDRGLTVVMVTHDSAIAKRVPHLARIKNGKLSVLREPEVSKLPADTRRLPGTAPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J2</accession>
    <name>C7Q9J2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS/PAC sensor signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5479"/>
    <dbReference type="EnsemblBacteria" id="ACU74338">
        <property type="protein sequence ID" value="ACU74338"/>
        <property type="gene ID" value="Caci_5479"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5479"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_2_11"/>
    <dbReference type="OMA" id="TRFWRGS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="41437" checksum="75B05943BDD0A4C4" modified="2009-10-13" version="1">MTVSVGARGARSGMRLFAGALDGLLVADDLPDGFVAADSEGLVRVFNRAAVTLTGIPADSALGRPFDEVLPLRTVDGRDWWGLTDPYGGLSIRTGHREAQLFLPEDPGKDDPEAGTELLVTARYQRRDGRSTPVTGLVVALRGTQARRRRERRQSDLIATVAHELRSPLTSVKGFTATLLARWDRFTDDQKRMMLQTVDADADRVVRLIAELLDVARLDSGRMELHRIPVDLRGLITDQVRACVAQGVPEETFRIRIPRGLPPVAADPDKLRQVLANLLENAVRHGGGTVTIEARAEDDRFRPDSLHTEGVSSVAVAVSDQGPGIPDDQLTRVFTRFWRGGRRGGTGLGLSIVKGLVEAHGGLVSVGNGADGGARFRFTLPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z0</accession>
    <name>C7Q9Z0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785682.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1465"/>
    <dbReference type="EnsemblBacteria" id="ACU70388">
        <property type="protein sequence ID" value="ACU70388"/>
        <property type="gene ID" value="Caci_1465"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1465"/>
    <dbReference type="eggNOG" id="COG1087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_11"/>
    <dbReference type="OMA" id="GEHLICN"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="9">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="34121" checksum="553FE4CAD7B67E4D" modified="2009-10-13" version="1">MRLLVIGGAGYVGSVTSAVLVEAGHEVTVVDDLSTGHRDAVPAGAAFRHADVLDQRQLGDVLREVAAGGPIDAILHFAARSLVGESVVEPARYFRHNITTTANLLEAMRDHGIGTIVFSSTAACYGEPDATPITEDMPTVPTNPYGASKLAADQMLTFAAPAYGIAAVSLRYFNVAGAYGPQGERHEVETHLIPRLLDVAAGNAPEASVFGTDYPTPDGTAIRDYIHVRDLAEAHLLALGAAKQGEHLICNLGTGTGFSVYEVLEAVRKATGAAVPAAEKPRRAGDPARLVASAERARTVLGWSPERTELSETVADAWAFYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z7</accession>
    <name>C7Q9Z7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785689.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1472"/>
    <dbReference type="EnsemblBacteria" id="ACU70395">
        <property type="protein sequence ID" value="ACU70395"/>
        <property type="gene ID" value="Caci_1472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1472"/>
    <dbReference type="HOGENOM" id="CLU_1018169_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="27361" checksum="30AAE4FE8E4D286D" modified="2009-10-13" version="1">MTENPNTPPDPNAGPPPGGPVDRPTTPAQPTPAPTPAPAQPSGSTQPTAEGAQPLGDAPKTGAETASGASTGSAAAAAAPAGASVAEPGSESSMTQDPATGAYTENPWGTAPEEGSELGGPADPNAPNTGVAATFLPGIDAASILALVLAALAAGAYLLVNPLVQAHDAARTWSDFKNNVPRTKQDPFGVQRDWVSYQSWAQIILGLVAVLLALVVLALWTARKNKLRSRAIAQAALVLGLAVVLYGILLKTGAVGSEIPSMKDISTGLSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA46</accession>
    <name>C7QA46_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase, subunit ChlI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785738.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1523"/>
    <dbReference type="EnsemblBacteria" id="ACU70444">
        <property type="protein sequence ID" value="ACU70444"/>
        <property type="gene ID" value="Caci_1523"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1523"/>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026145_1_0_11"/>
    <dbReference type="OMA" id="STNPCPC"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
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    </dbReference>
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        <location>
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            <end position="402"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="517" mass="54541" checksum="07F944908413F615" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAE0</accession>
    <name>C7QAE0_CATAD</name>
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        <recommendedName>
            <fullName evidence="6">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3534</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
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            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3534"/>
    <dbReference type="EnsemblBacteria" id="ACU72439">
        <property type="protein sequence ID" value="ACU72439"/>
        <property type="gene ID" value="Caci_3534"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3534"/>
    <dbReference type="eggNOG" id="ENOG5033QWN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128123_0_0_11"/>
    <dbReference type="OMA" id="RERRYDW"/>
    <dbReference type="OrthoDB" id="1518350at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="6">
        <location>
            <begin position="14"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18937" checksum="E5055A0F6B7C078B" modified="2009-10-13" version="1">MADAVTLPLRERKIDVFFAVVFSAFVVTSCISDLLPTVGVDFSHPGGNFFVRSNYWYAHDADPLFMHPPDWMRIVTGLSAFVYMPFYIVLVVALITGRNWIQLFAVIYATMIVTLTGIVVFGVEFFGEAAMRTGNPTKFLAFNLPYVLIPLLLLVRMRKPSPFTRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAH7</accession>
    <name>C7QAH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3571</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3571"/>
    <dbReference type="EnsemblBacteria" id="ACU72476">
        <property type="protein sequence ID" value="ACU72476"/>
        <property type="gene ID" value="Caci_3571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3571"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023176_0_0_11"/>
    <dbReference type="OMA" id="MYKGNAT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982957" evidence="9">
        <location>
            <begin position="26"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="10">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="11">
        <location>
            <begin position="334"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="564" mass="58297" checksum="B62700FE5C8CDB83" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL8</accession>
    <name>C7QAL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792246.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3614"/>
    <dbReference type="EnsemblBacteria" id="ACU72517">
        <property type="protein sequence ID" value="ACU72517"/>
        <property type="gene ID" value="Caci_3614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3614"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1254075_0_0_11"/>
    <dbReference type="OMA" id="ANEWIRT"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="12"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="220" mass="22610" checksum="56D08590819DEBE5" modified="2009-10-13" version="1">MTNSTSLPVIAAFGDSLTKGDGSTPDASTAYVDVLARRLGVPVRNRGISGNRLLCDGYGPAGTDRFAADVLADAEVTHVILELGVNDIGLAGVEGSAMPSAEALIGGLSALAERAAAAGLVVIGATLTPHRGTRYPGFFSQAGEEIRKAVNLWIRSAACFAAVLDIDAALRDPERDGYIAPDLDYGDGLHPNDAGHRAIAEAFDAAVLENTAGVSEFCDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAR8</accession>
    <name>C7QAR8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5532"/>
    <dbReference type="EnsemblBacteria" id="ACU74391">
        <property type="protein sequence ID" value="ACU74391"/>
        <property type="gene ID" value="Caci_5532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5532"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108054_2_1_11"/>
    <dbReference type="OMA" id="RPGANWR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="13"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14312" checksum="D0CE36DE37AD12B6" modified="2009-10-13" version="1">MRSRRSGMWWGTAIEAPDPSALARFYSELLDWPIGHEEPGTAILAPAPEGPYFVFQQADGFRPPVWPPVEGEQRPMVHFDFQVGDLDEAVAEALALGATLASHQPQDNVRVLLDPAGHPFCLCYDGDDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBA3</accession>
    <name>C7QBA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796119.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7570"/>
    <dbReference type="EnsemblBacteria" id="ACU76394">
        <property type="protein sequence ID" value="ACU76394"/>
        <property type="gene ID" value="Caci_7570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7570"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533910_0_0_11"/>
    <dbReference type="OrthoDB" id="689314at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="511" mass="55289" checksum="BE85863483285787" modified="2009-10-13" version="1">MNAPALILNLLHAARREDVAPVLALLSDAELAAGLASEHCDPQLRTVAVDREALCHALLDPRETPEDLPTKAGGVQGMVRLAARAPYQTVLPGGITPYGRPQADLRHRLAAGLNAALGTDAWRWYGAMCLVDVWSGSFGALLDEVAGWSTESQLPKSSMRFRLKGQVFLPGVLLAMAPPAVVAAALPYTAERSVGMIQGLLIHAPYHPAYQDYAFGPDGSDYARQSLCQSVGTPLAVAHELLDRELFHQNVEAVAYGHDDLALRLRIYRDPDSDTPWQTSRLDHTTPEEFYALLSATETAEEIFDLLSILRRAMERTPAIGKLRIFAYSRLAQLAGPEPVWTLELASAGGVELLVHPAVRASMAAGDIAPIVAAAEAAAENVPGPPPPAPNQDSLTDWPLEDAVRGGLDGRPERWQTMLESYDKATESPLALVQWATGQSVRPAARDREDLTQSTNRPENQPENQLEKQPENQPANRPPHRPTNPAPHHPTNHPTPPPPPPAPTPVQEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBA4</accession>
    <name>C7QBA4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796120.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7571"/>
    <dbReference type="EnsemblBacteria" id="ACU76395">
        <property type="protein sequence ID" value="ACU76395"/>
        <property type="gene ID" value="Caci_7571"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7571"/>
    <dbReference type="eggNOG" id="COG3864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585134_0_0_11"/>
    <dbReference type="OMA" id="KWIWLIT"/>
    <dbReference type="OrthoDB" id="339197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="52112" checksum="E32B09E7891A6E45" modified="2009-10-13" version="1">MKTHESDRRSRRLPVSATDRKALAAWQPAEPETIAEAVRLKEAALVDFGMESSAIAGWIYSKCAHQVPTTAIETAAVMAAGDGTCLLLFNPDFFVELGLDGVKFVLFHEARHLIQRHLFTEPELREDPVFDIAIECTINHVALTRLRRQSLPVAGGEPTGVDPRKVFARYHADLTAQGLTPFSYEEFIHTDMGCYTELRRMKHPPTPPPICVHELLQELQDELADAETIARIGNEVLANVLLAGKRGVREARSELLDLIARTEGATERLSKLWGDLGAGMIRGQTQRTRRVDWWQRWLVDVLASKLAEGERLVYPKKRGAVLAALGEDPTLSRRGPERHRVVAIAVDASGSMPPPVVDWIASLVGQLDGVEAHWLSFDAAVVPFAPGDPLVGGGGTSFQAVADYLEGRAPSARTGEPFEETLDAVIMVTDGIAPHITPAEPDKWIWLITEHGDDWPESHTPQMACHTVRTGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBB7</accession>
    <name>C7QBB7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76408">
        <property type="protein sequence ID" value="ACU76408"/>
        <property type="gene ID" value="Caci_7584"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7584"/>
    <dbReference type="HOGENOM" id="CLU_728992_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045596">
        <property type="entry name" value="DUF6459"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20060">
        <property type="entry name" value="DUF6459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="39745" checksum="CC3E493F5015CB48" modified="2009-10-13" version="1">MTPVRSVRAIGTAGVGAHWRRDNRPDFPGIAVWVDAVAEIEIETGAFGDSDEEGEFSAGERAGGESRSSGRGSDWADGERGSAGQGDSERADGESRGSRHIGDWADSESLGSDQGAGARASAARLGSDWVDGESRGSDQSAGARANGQRLGGDWADGESLGSDQSAGARPNGQRLGGDRSAGSQDSDDAGLVPSSVDAWSPEYAKVWRPLSGAGREPRPGLLVSVVRAGAVVAYPTPLPDPPTGALARALARLERPAVERRPHILPIEAAPAPAPPRRPAPSQKTYGEVRALVGVLVEILRGHRAATHAARWTDPEVRGKLRTPRYARTASLKSVRLAESGDGVEALALLQEGGRTHVVALRFDRAEDSRWRCTALQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBL7</accession>
    <name>C7QBL7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trpD</name>
        <name evidence="6" type="ordered locus">Caci_1673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785888.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1673"/>
    <dbReference type="EnsemblBacteria" id="ACU70594">
        <property type="protein sequence ID" value="ACU70594"/>
        <property type="gene ID" value="Caci_1673"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1673"/>
    <dbReference type="eggNOG" id="COG0547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034315_4_1_11"/>
    <dbReference type="OMA" id="GPMTNPA"/>
    <dbReference type="OrthoDB" id="1238435at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="5">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="4">
        <location>
            <begin position="78"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="87"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="112"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="36574" checksum="AF3F66ED6AAF8177" modified="2009-10-13" version="1">MTEQRTWPELLSAVLRRDDLSVDDAAWAMDRIMTGEATPSQVAGFAVALRAKGEAVDEIEGFVRSMYTHALLIDVPGATVDIVGTGGDRAHTVNISTMSAIVAAGAGATVVKHGNRASSSSSGAADVLERLGVRLDLPPEAVAQVAKEVGITFCFAPVFHASLRHAGVPRKELAIPTFFNFLGPLTNPARPRASAVGVFDDRMAPIVAGVFARRGVESLVFRGDDGLDEISVATTTTVWTATGGTVIREVFDPRDVGIEYSPISALRGADPEFNATVARRLLAGERGAVRDAVLLSSAAALAALEPSGAPVAQRLGAGLAKAADAIDSGAAERVLAKWVEVSERLIRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBS7</accession>
    <name>C7QBS7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792275.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3644"/>
    <dbReference type="EnsemblBacteria" id="ACU72546">
        <property type="protein sequence ID" value="ACU72546"/>
        <property type="gene ID" value="Caci_3644"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3644"/>
    <dbReference type="eggNOG" id="ENOG5032R61">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2421564_0_0_11"/>
    <dbReference type="OrthoDB" id="1739497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="10335" checksum="1BBD58C91F654C08" modified="2009-10-13" version="1">MRKAHGWTADDVRGHLDIGEWEFALAMLVDVSDQNSQSVRYRQLLAEVADLLRLDRSVAWCHWRAYEAVNGVISTDLALAAPEGGGRQWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC87</accession>
    <name>C7QC87_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">polA</name>
        <name evidence="15" type="ordered locus">Caci_5677</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5677"/>
    <dbReference type="EnsemblBacteria" id="ACU74535">
        <property type="protein sequence ID" value="ACU74535"/>
        <property type="gene ID" value="Caci_5677"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5677"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_0_0_11"/>
    <dbReference type="OMA" id="NRPPMPD"/>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="13"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="320"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="661"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU74535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="905" mass="98463" checksum="9C3AB77E3550F027" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCG8</accession>
    <name>C7QCG8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7607"/>
    <dbReference type="EnsemblBacteria" id="ACU76431">
        <property type="protein sequence ID" value="ACU76431"/>
        <property type="gene ID" value="Caci_7607"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7607"/>
    <dbReference type="HOGENOM" id="CLU_031881_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043777">
        <property type="entry name" value="DUF5719"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18986">
        <property type="entry name" value="DUF5719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="582" mass="59425" checksum="C0B737FA3906D243" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH5</accession>
    <name>C7QCH5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796163.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7614"/>
    <dbReference type="EnsemblBacteria" id="ACU76438">
        <property type="protein sequence ID" value="ACU76438"/>
        <property type="gene ID" value="Caci_7614"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7614"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_2_11"/>
    <dbReference type="OMA" id="ARGYHFR"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="17183" checksum="BE352E74DA2DD95C" modified="2009-10-13" version="1">MDPLGAPTRLHGSVIWLLGQTSNQGHRLIGERMHATGVPSRSYYPLLAALAESGATSQADLGRRIGLDRSDVTAAVTDLEGRGYLDRAPDPADRRRNLVRITEEGERFLGTLDGHLDSAQDELLDPLSPQERESLQGMLARLVLHHTGLRISGTEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCP0</accession>
    <name>C7QCP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
            <ecNumber evidence="6">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796228.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7679"/>
    <dbReference type="EnsemblBacteria" id="ACU76503">
        <property type="protein sequence ID" value="ACU76503"/>
        <property type="gene ID" value="Caci_7679"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7679"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_4_11"/>
    <dbReference type="OMA" id="ITRWGNQ"/>
    <dbReference type="OrthoDB" id="535707at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="138"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="526" mass="55908" checksum="947225FFFAF0EF76" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD75</accession>
    <name>C7QD75_CATAD</name>
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        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3766</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3766"/>
    <dbReference type="EnsemblBacteria" id="ACU72668">
        <property type="protein sequence ID" value="ACU72668"/>
        <property type="gene ID" value="Caci_3766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3766"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="NITMAPR"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="16"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="28133" checksum="606A53F0D6501D10" modified="2009-10-13" version="1">MSAAVQTQTQTRAAAVEIRGVTKSYGALKVLDGVDLTIQPGQVAVLLGPSGGGKSTLLRTVNHLEKPDAGHVSVNGRLIGVRQHGSRLKELSERAILAQRAEIGFVFQSFNLFPHLTALENVAAAPVATGRATKAEAREHAVELLTRVGLADKADVYPRQLSGGQQQRVAIARALAQSPGLILFDEPTSALDPELVGEVLGAIKDLADSGTTLIVVTHEVGFAREIADLVVFLDGGKVLEQGSPQEVLDNPRYRRTREFLSKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDM8</accession>
    <name>C7QDM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5794</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794381.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5794"/>
    <dbReference type="EnsemblBacteria" id="ACU74652">
        <property type="protein sequence ID" value="ACU74652"/>
        <property type="gene ID" value="Caci_5794"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5794"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_1_11"/>
    <dbReference type="OMA" id="TAYYTDH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="38"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="118"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="35592" checksum="7F3520901B1CDC40" modified="2009-10-13" version="1">MTSSPTLPTPGITVYGCGQDEAVLFRALATRFGFVPTITEAAVSEANAELASGNRCISVGHKTQITDATLLALSRVGVTYISTRSIGYNHLDVGFANSVGISVENVSYSPDSVADYTLMLMLMAVRHAKSLVRRTDVHDYRLHDVRGRELRDLTVGVVGTGRIGAAVVDRLKGFGCRVMAHDRNPESVAGYAPLDELLRHSDIVTLHTPLTAETHHLLNSERIEQMKPGVFIVNTGRGSLLDTEALLQALESGRLGGAALDVLEGEEGIFYADCRDRVIESKTLLRLQELPNVLVSPHTAYYTDHALSDTVENSIINCLRFESGNHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE49</accession>
    <name>C7QE49_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylated-DNA-(Protein)-cysteine S-methyltransferase DNA binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7813"/>
    <dbReference type="EnsemblBacteria" id="ACU76637">
        <property type="protein sequence ID" value="ACU76637"/>
        <property type="gene ID" value="Caci_7813"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7813"/>
    <dbReference type="eggNOG" id="COG3695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_5_11"/>
    <dbReference type="OMA" id="MRTDSAD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="13443" checksum="82982746C665ED50" modified="2009-10-13" version="1">MTKPPELPPYVERVFDVVDRIPPGRVMAYGEVAEWLGEGGPRQVGTAMAKYGGGSPWWRVVRSDGGFLPGHEREALANYREEGTPLKPDGGRVDMVRARWWPAEDGTVGSGAMDEVPSDFAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE51</accession>
    <name>C7QE51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBA/THIF-type NAD/FAD binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7815"/>
    <dbReference type="EnsemblBacteria" id="ACU76639">
        <property type="protein sequence ID" value="ACU76639"/>
        <property type="gene ID" value="Caci_7815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7815"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_1_1_11"/>
    <dbReference type="OMA" id="MIYDALE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="301"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="42743" checksum="5D92DF2AFB7DB0F9" modified="2009-10-13" version="1">MSNLPPLVEPAADLTVEEVRRYSRHLIIPDVGMAGQKRLKNAKVLCVGAGGLGSPTLLYLAAAGVGTLGIVEFDVVDESNLQRQVIHGQSDIGRSKAESARDSITEINPLVRVNLHEERLDSTNVMELFAQYDLIVDGTDNFATRYLVNDACVLLNKPYVWGSIYRFDGQASVFWSEYGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQVNEAIKLLAGIGEPLVGRLMIYDALEMTYRQVKVRKDPDCAVCGEHPTVTELIDYEAFCGAISEEAADAAKDSTITVTQLKEWLDTDEKIQLIDVREPNEYEIVNIPGATLIPKGEFLMGTALEKLDPTKRIVLHCKSGVRSAEALAVVHAAGYKDAVHVGGGVLAWVNQIEPEKPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEG6</accession>
    <name>C7QEG6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786150.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1937"/>
    <dbReference type="EnsemblBacteria" id="ACU70857">
        <property type="protein sequence ID" value="ACU70857"/>
        <property type="gene ID" value="Caci_1937"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1937"/>
    <dbReference type="eggNOG" id="COG1878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030671_2_0_11"/>
    <dbReference type="OMA" id="GKYGLTQ"/>
    <dbReference type="OrthoDB" id="831439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="27797" checksum="CA6ADC86F8F7B511" modified="2009-10-13" version="1">MTLLVQLAEAVAAGTIEVVDLTAPLSHETPILHLPEPFNNTVQFSLREISRYDERGPAWYWNDIVTGEHVGTHFDAPVHWITGRDGEDVSQVAPRRLIGPAVVLDASERAAQDPDHLLQVEDVREWESKYGPLPEGGWLLYRTGWDARAGDQAAFLNANETGPHSPGFSVECAKWLAEETPLQGIGVETVGTDAGAAHSFDPPFPCHSSMLGAGKYGLTQLRNLDRLPARGAVLIAAPLPIVRGSGSPARVLALVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN7</accession>
    <name>C7QEN7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792536.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3921"/>
    <dbReference type="EnsemblBacteria" id="ACU72807">
        <property type="protein sequence ID" value="ACU72807"/>
        <property type="gene ID" value="Caci_3921"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3921"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_11"/>
    <dbReference type="OMA" id="RIMAFTR"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="25671" checksum="93766BA2072428BB" modified="2009-10-13" version="1">MVETENDGNGNGTAATRQEQAYEELRSLLLSGAIEPNTRLTEADLTSRFNVSRSTMRAVLVHLAQEGYVTSEVNRGVRARSFSPQEARDILEAREVLEAALAAKAAERATEEDISRLRETLAAMHEAHTGGDQVAYVRGNRLFHQQVKAAAHARTLARAYDTLLYPMVIRQYRDISRHHPRSGSFEEHQAILLGIVTGNPEAAAAAMRHHVSAARHALVLPESAESAQSTDPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEU0</accession>
    <name>C7QEU0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Blue (Type 1) copper domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3984"/>
    <dbReference type="EnsemblBacteria" id="ACU72860">
        <property type="protein sequence ID" value="ACU72860"/>
        <property type="gene ID" value="Caci_3984"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3984"/>
    <dbReference type="eggNOG" id="COG3794">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084115_2_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981585" evidence="1">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="2">
        <location>
            <begin position="58"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="13955" checksum="361FAA2A3802AEF9" modified="2009-10-13" version="1" precursor="true">MFRLSGKAAAAMCLAVATACAVTACSDNGSHPVAAPNSVPAVSNSSPSSGETGVSNGAAQVVITNFAFSPTTLTVTPGETVTVLNKDSTAHTLTATGKAFDTGDITPGKSGSFIAPTIPGTYSYICMIHQFMHGTLTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF24</accession>
    <name>C7QF24_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794511.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5924"/>
    <dbReference type="EnsemblBacteria" id="ACU74782">
        <property type="protein sequence ID" value="ACU74782"/>
        <property type="gene ID" value="Caci_5924"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5924"/>
    <dbReference type="eggNOG" id="ENOG5032YW5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064093_2_0_11"/>
    <dbReference type="OMA" id="PVPWVCL"/>
    <dbReference type="OrthoDB" id="680274at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="35131" checksum="CD14F43D6257119A" modified="2009-10-13" version="1">MSPHDFKPVMHPAGFDEPMARILGEVRTGHWFSMAEMLAASGGDRRLRCTRIALLAQVAAASNAVDQWVAERPRDPDAVAMAARVAVERACKAAAKGLAQAQGMGRRAAELCAEAAAMDPADPVPYLGRLALAAGFGERVEGPDSCPVPGPWHAFRDLWRIDPANREGAHRMLSAVGSGAAPSPAAAQLFASSIVSSVGLSSLSPLQLLPLYAIVVAYEYRKAQGDGLAHLLWTTETARTEMARGWNWFASSGKQDWLVVDLSHLAHALVVGGRADLAADVFEAMGPYGSNRPWTVASGSGDAVEEFVRARSTALAAAASRRGGTSGRQRAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF65</accession>
    <name>C7QF65_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794552.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74823">
        <property type="protein sequence ID" value="ACU74823"/>
        <property type="gene ID" value="Caci_5965"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5965"/>
    <dbReference type="HOGENOM" id="CLU_2877529_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="63" mass="7516" checksum="1F877D81C144A680" modified="2009-10-13" version="1">MNTVIERERQDNEWGPVTIVHTWGGWPWRAQCEECTTRSPGQRTHEEARQWADSHYHAFHEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF85</accession>
    <name>C7QF85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794572.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5985"/>
    <dbReference type="EnsemblBacteria" id="ACU74843">
        <property type="protein sequence ID" value="ACU74843"/>
        <property type="gene ID" value="Caci_5985"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5985"/>
    <dbReference type="eggNOG" id="COG3553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127482_0_1_11"/>
    <dbReference type="OMA" id="PARYIKQ"/>
    <dbReference type="OrthoDB" id="1858344at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014543">
        <property type="entry name" value="UCP028291"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09981">
        <property type="entry name" value="DUF2218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10766" checksum="BD52686AE244C866" modified="2009-10-13" version="1">MIESVATVTTDRPERYLKQLVSHLGREVDAEQSEDGHSGALIFSSGNCALSAEPGMLRLTARAQDDERLAAVETVVARHLVRFGEKDALVVVWSAAMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFH7</accession>
    <name>C7QFH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin biosynthesis MoaE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7931"/>
    <dbReference type="EnsemblBacteria" id="ACU76754">
        <property type="protein sequence ID" value="ACU76754"/>
        <property type="gene ID" value="Caci_7931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7931"/>
    <dbReference type="eggNOG" id="COG0314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089568_1_1_11"/>
    <dbReference type="OMA" id="GEICLFV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="16487" checksum="FD0E1F9F2E6EB9FC" modified="2009-10-13" version="1">MIEEKEQESVTAGHTAGRTVIHTDVREEPLSVDEVVAAVTHQSAGGIALFIGVVRDHDHGRSVTALDYSAHPSAAELLAKVAEDIAEAHPDVVAVSAVHRVGALTVGDLAVVVGASAPHRAEAFAACRAFIDTLKAQVPIWKREEFADGDHEWVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR3</accession>
    <name>C7QFR3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0047"/>
    <dbReference type="EnsemblBacteria" id="ACU69002">
        <property type="protein sequence ID" value="ACU69002"/>
        <property type="gene ID" value="Caci_0047"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0047"/>
    <dbReference type="HOGENOM" id="CLU_926502_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021202">
        <property type="entry name" value="Rv3654c-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03816">
        <property type="entry name" value="tadE_like_DECH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Tad" evidence="2">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="30430" checksum="277D8A077DF3AB98" modified="2009-10-13" version="1">MPPPNPARDRGSATIYAALLTGLLTTLTGAILALGTAILARHRAGSAADLAALSAATHATPGQIPCDWARRVTTAHHTRLLHCTCNGPTCLVTTAINTPWGAATVTSRAGPADDPTGETTAGQNALRAEGTRLAEAAMGLRAAALSDPVGERIAGIERTRLGEATGGSLRTAAMTSRTHDPVGERTVEVERSSRAKPQATAPRAANLVGRTGLTHGLVGPSLVGIERSTYAEAYPFGKRASGIAARLTTPAVASRPRPSPHRAPVVPAAPLVGVRLAVAESEPLAGSSAASCCQLGAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG61</accession>
    <name>C7QG61_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4038"/>
    <dbReference type="EnsemblBacteria" id="ACU72906">
        <property type="protein sequence ID" value="ACU72906"/>
        <property type="gene ID" value="Caci_4038"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4038"/>
    <dbReference type="eggNOG" id="ENOG5032ZM5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135445_0_1_11"/>
    <dbReference type="OMA" id="TGAQQLD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tad" evidence="1">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="12251" checksum="9C66750D0B3BB2A4" modified="2009-10-13" version="1" precursor="true">MVTAFTVVIVIALMVFVGLAYDGGRALDGRVKALNEAQEAARAGAQALNLGALRAGGTAVLDPEAAVGAAKAYLAGTGDAGTVDVAGTTVTVSVTHVQATKFLGLVGVGSITAHVTASARAEQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA1</accession>
    <name>C7QGA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792675.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4081"/>
    <dbReference type="EnsemblBacteria" id="ACU72946">
        <property type="protein sequence ID" value="ACU72946"/>
        <property type="gene ID" value="Caci_4081"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4081"/>
    <dbReference type="eggNOG" id="ENOG502Z84P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060481_0_0_11"/>
    <dbReference type="OMA" id="PATHNDR"/>
    <dbReference type="OrthoDB" id="1355200at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024414">
        <property type="entry name" value="Uncharacterised_PrgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12666">
        <property type="entry name" value="PrgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="33967" checksum="F3720047BFE3883F" modified="2009-10-13" version="1">MREEEQARYATRIPADVDRPDVIVARLTARQVVVLAATGLLVWAGFMTAHAALPKVPSAYLIAPAAPIAAIAIGLALGKRDGLTADRFVLAALRHGRAKKHLVPSGEEQTPALPEFLPKAVRAKAGPAPAAMTMPARGIDETGVFDLGAEGFSALAACGTVNFALRTAGEQDALVAAFGRWLNGLTAPVQLLVRTHRLDLSGAVDQLRAAAPSLPHPALEQAAAEHADYLEALAGRRDVLHRQVLLAAREPRTGRGRKTSAASPDASAPMRLHRRVDEAARALSGAQIPVRAFESERLRHLLTDATGAGQEAEPLEGETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGH4</accession>
    <name>C7QGH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low temperature requirement A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5996"/>
    <dbReference type="EnsemblBacteria" id="ACU74854">
        <property type="protein sequence ID" value="ACU74854"/>
        <property type="gene ID" value="Caci_5996"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5996"/>
    <dbReference type="eggNOG" id="COG4292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045667_2_1_11"/>
    <dbReference type="OMA" id="WIGASRI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="PTHR36840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="44163" checksum="D91031C585264AAE" modified="2009-10-13" version="1">MVAVASEDYPDTPTESGGDDGSAGITADDGGPDRGRSPHAVQRVTWAELFFDLVFVFAVTQVAHAVSVGDGWADLGRSILLFVPFWWAWVGCAILFNGMVISATKRHLVLLAIAGAAFVMCISVPDAYGNRGVLFGAAYLVSRILLGATMRVRDAFKVRLDPFTVGVLAGLAWMFAGLLPSDTRQWVWLALALIELAVPLVLGHRLDYMQFDASHLPERFGLFVIIALGETLVGIGQGGTRNALHGEEAVTLFVAFLLSCGLWWTYFQYGASATEHALKVAKVPAILVRSSFSYGHMLFVLGIILAAAGMSQAVADPTARLHGVHALLLGSGVSLYVATFCYTRIMMFGGASYTRVVAALLAIVVTACSPALPAIVPLALLAALVIALNAFEFYWVTAGKPLMLINVWQGAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM3</accession>
    <name>C7QGM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6046"/>
    <dbReference type="EnsemblBacteria" id="ACU74903">
        <property type="protein sequence ID" value="ACU74903"/>
        <property type="gene ID" value="Caci_6046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6046"/>
    <dbReference type="eggNOG" id="ENOG5033WI4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1084589_0_0_11"/>
    <dbReference type="OrthoDB" id="1715251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="28542" checksum="224CBFA98B350AD7" modified="2009-10-13" version="1">MGWMSKLFGSEEEIGPEEAHRRAAEADKGSKAPAKKTAAKRAASSEHEHADRPAAKKAVPAPRAAAHSHEPARTASPTHPTVSRATGKTLEHDQMLTVHILTHVPEHSPREDDPHYHLFEQAKARLKRQGMWKCIIDDDLCDGDPELHHTHVEFSQINQVDEKKIMQALGLHFETDEDFQKWAESPGNLEVLCANHHRAHYGIHVIPGPLWEALRFHKTGTGPAAEFIPADKLDDRDKDDDDDKPAVRTAAKKTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGT3</accession>
    <name>C7QGT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74963">
        <property type="protein sequence ID" value="ACU74963"/>
        <property type="gene ID" value="Caci_6108"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6108"/>
    <dbReference type="HOGENOM" id="CLU_1438696_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983133" evidence="2">
        <location>
            <begin position="39"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="18830" checksum="F76B3135F3398071" modified="2009-10-13" version="1" precursor="true">MALTSKQKKQGAAVSAAIGVLALGGVAASTLGSGGAAADRPVAVAAVQQAAAAPQVVAGAGESVGGITVIARVDNVKLADDTVFTVSGEVKGAKPGTKVRLQRKTSGKSATGWTTLAYTTFTDTSNKFSFPVKMDSSGSYTLRILHPQDKEGPATVYSSPFSVTVSAPAKAGTSSKASESSKTPVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH54</accession>
    <name>C7QH54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c biogenesis protein transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796629.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8081"/>
    <dbReference type="EnsemblBacteria" id="ACU76904">
        <property type="protein sequence ID" value="ACU76904"/>
        <property type="gene ID" value="Caci_8081"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8081"/>
    <dbReference type="eggNOG" id="COG0785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053225_2_1_11"/>
    <dbReference type="OMA" id="TSLTPCM"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="35"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="274" mass="28691" checksum="F54AF0284AFF5479" modified="2009-10-13" version="1">MSATAAVLTHLASSYTSTETRVEYGSFLVAVPIALAAGLISFLSPCVLPLVPGYLSYVTGLTGVDLGTQTLDEAARAKRGRMIAGALLFVLGFSIVFVLLEAVAGWSGQFLLVHKRAIQIVLGGITILMGLSFAGVVPGVISRVFNREARFHTDPRVGLAGAPLLGILFGLGWTPCMGPTLSAVSSLSIDSGNAGRSVLIGVAYCLGLGLPFVLTAIAFRKAMGAFGYVKRHYQAVMRIGGGMLVLIGVLLVTGQWDHLVTWLQGQTPGFQSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN4</accession>
    <name>C7QHN4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786352.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2140"/>
    <dbReference type="EnsemblBacteria" id="ACU71059">
        <property type="protein sequence ID" value="ACU71059"/>
        <property type="gene ID" value="Caci_2140"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2140"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="GIAQHEN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="371"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="532" mass="54784" checksum="A7325BBB47C9590A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHU7</accession>
    <name>C7QHU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YibE/F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786415.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71122">
        <property type="protein sequence ID" value="ACU71122"/>
        <property type="gene ID" value="Caci_2203"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2203"/>
    <dbReference type="eggNOG" id="COG5438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028166_3_1_11"/>
    <dbReference type="OMA" id="VMLYDRP"/>
    <dbReference type="OrthoDB" id="1746642at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012507">
        <property type="entry name" value="YibE_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41771">
        <property type="entry name" value="PTHR41771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07907">
        <property type="entry name" value="YibE_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="599" mass="60989" checksum="D3F6308B662D1B2E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHY0</accession>
    <name>C7QHY0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4161"/>
    <dbReference type="EnsemblBacteria" id="ACU73025">
        <property type="protein sequence ID" value="ACU73025"/>
        <property type="gene ID" value="Caci_4161"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4161"/>
    <dbReference type="HOGENOM" id="CLU_3249003_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="42" mass="4822" checksum="382070B1D555EDD8" modified="2009-10-13" version="1">MIPQELHEEAGRQARDERTARDAARNPALPAHVMREMARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI36</accession>
    <name>C7QI36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792810.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4217"/>
    <dbReference type="EnsemblBacteria" id="ACU73081">
        <property type="protein sequence ID" value="ACU73081"/>
        <property type="gene ID" value="Caci_4217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4217"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_3_1_11"/>
    <dbReference type="OMA" id="GSCMTMG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="61845" checksum="166FE60D82EE1743" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIA8</accession>
    <name>C7QIA8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794714.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6131"/>
    <dbReference type="EnsemblBacteria" id="ACU74985">
        <property type="protein sequence ID" value="ACU74985"/>
        <property type="gene ID" value="Caci_6131"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6131"/>
    <dbReference type="HOGENOM" id="CLU_1507990_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="18673" checksum="5C62F4CF9CC81A19" modified="2009-10-13" version="1">MVTENGRAELREFYTDPALPLTIAVGQAFDLVSMPAAVGHAALAALRARRVRLGPVVADSRKSVMRVGFLVAPAHAPDSPHSTRSLRAEVGTSPETVLYAQNGAGHAETAALRDWVGRLGGALGVRVGGRGSTATLPPLLPWRGWLHWLVPPGTPAVLWTPAGALLTVLSERTGARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ96</accession>
    <name>C7QJ96_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784533.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0285"/>
    <dbReference type="EnsemblBacteria" id="ACU69238">
        <property type="protein sequence ID" value="ACU69238"/>
        <property type="gene ID" value="Caci_0285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0285"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081211_1_0_11"/>
    <dbReference type="OMA" id="DTTGPLH"/>
    <dbReference type="OrthoDB" id="1059710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="16"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="30793" checksum="BF758F66A028C757" modified="2009-10-13" version="1">MSHSTFNTPAAIAVALDLYVADVRIVAADRADTVVEVRPSDPNKAADVKAAENTRVEYDEGARVLSIVSRKPRNRFVNFSSKRPESIDLLIEVPTDSDVRGETEIGDFESVGVLGAVQLKAGVGTVRLAQVGPVNIRDGVGEVLIEEVSGAADVNCGSGVIRLGAVDGTAEVSNGNGKVRVGVVTGAANVKSANGEVSVDRALSDITASASNGEVRVGEVVRGKATVTSKNGAVEVGVREGSAAWLELSTAVGRVYNELESADAPQAGEPVDKVEIHASTKLGDVTIRRVPRLDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJL3</accession>
    <name>C7QJL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786529.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2318"/>
    <dbReference type="EnsemblBacteria" id="ACU71236">
        <property type="protein sequence ID" value="ACU71236"/>
        <property type="gene ID" value="Caci_2318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2318"/>
    <dbReference type="eggNOG" id="COG2153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056607_3_1_11"/>
    <dbReference type="OMA" id="VEQSHVC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="16193" checksum="C13C34F44CFD0C17" modified="2009-10-13" version="1">MGKVSYRYAHIEDLDAPTIYALLRLRQEVFIVEWGSSHLDIDGRDTEPSSVHLWAERDGDVLAAVRVVQESDDTLRIERLATRFGARGRGIAGRLLDYAVKMAGERRLLIDVPTALEPWAERFGFARAGDPFIAEGVQQVTMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJS5</accession>
    <name>C7QJS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4299</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792892.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4299"/>
    <dbReference type="EnsemblBacteria" id="ACU73163">
        <property type="protein sequence ID" value="ACU73163"/>
        <property type="gene ID" value="Caci_4299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4299"/>
    <dbReference type="eggNOG" id="COG4779">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_1_1_11"/>
    <dbReference type="OMA" id="AWKRGVH"/>
    <dbReference type="OrthoDB" id="1283908at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983196" evidence="8">
        <location>
            <begin position="20"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="34658" checksum="5821B75C431C1022" modified="2009-10-13" version="1" precursor="true">MRVLRTTALSVRYRPRALTASVACLVLAFAAMVITLGSGDYRIPPGEVLRTLAGGGTVADHFIVVQLRLPRVVTALLVGGALALAGAAFQSLVRNPLGSPDMLGFTEGAATGALVVVVAGGSSLALAGGAMIGGVATGVGVYALAWRRGVHGYRLILTGIGVSAILSGVNGYLMTKAQLMDAARAMLWLTGSLDGRGWSDVVPLAVAMVVLVPVVVAGCGRALHIIEMGDDVARALGISVERVRLMTLAAAVLLTSFAAAAAGPVSFVALTAPQLARRLTRAPGPNLIPSMLLGSVLLTCADLVAQHAVPGRQLPVGVVTGVLGGGYLIWLLAAGRRAGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY4</accession>
    <name>C7QJY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4358"/>
    <dbReference type="EnsemblBacteria" id="ACU73222">
        <property type="protein sequence ID" value="ACU73222"/>
        <property type="gene ID" value="Caci_4358"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4358"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017262_1_0_11"/>
    <dbReference type="OMA" id="GWNRQLD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="572" mass="60096" checksum="C6AFA694CF0C8DB4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK47</accession>
    <name>C7QK47_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6267</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6267"/>
    <dbReference type="EnsemblBacteria" id="ACU75121">
        <property type="protein sequence ID" value="ACU75121"/>
        <property type="gene ID" value="Caci_6267"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6267"/>
    <dbReference type="eggNOG" id="COG2895">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_5_2_11"/>
    <dbReference type="OMA" id="TPYYDGP"/>
    <dbReference type="OrthoDB" id="244339at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04166">
        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03695">
        <property type="entry name" value="CysN_NodQ_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041757">
        <property type="entry name" value="CysN_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044138">
        <property type="entry name" value="CysN_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011779">
        <property type="entry name" value="SO4_adenylTrfase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02034">
        <property type="entry name" value="CysN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="8"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="456" mass="48334" checksum="DB425A6444D6F7D5" modified="2009-10-13" version="1">MGHEDPRQDLLRLATAGSVDDGKSTLVGRLLHDTKSVLADQLDAVRRASAERGLAAPDLSLLVDGLRSEREQGITIDVAYRYFATPRRSFVLADTPGHVQYTRNTVTGASTAQLAVVLVDARRGVVEQTRRHAAVLALLGVPRLVLAVNKIDLVGYDEPVFAAIAKEFLAYAGELGYADGHVLAIPVSALVGDNVVEPSDRTPWYTGPTLLDHLETVPVEPDPQDKPLRFPVQYVIRPRTQAHPDYRGYAGQIAVGMAAVGDEVLVLPAGLRSTVRGIDTMDGPLAQAHAGRSVTLLLADELDICRGDVIVAAGAPPTVTDELDATVCWLSDEPLRPGASVLLKHGTRTVSAMVAALHSRFDEQNLSTVEAPESLQLNHIGRVTLRTSQPLPVDDYSTSRRTGSFLLIEPSDGGTLAAGLIGMPLTVSAPAPVSASASAPVSAPAEARKPVAGMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKI1</accession>
    <name>C7QKI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796805.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8257"/>
    <dbReference type="EnsemblBacteria" id="ACU77080">
        <property type="protein sequence ID" value="ACU77080"/>
        <property type="gene ID" value="Caci_8257"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8257"/>
    <dbReference type="HOGENOM" id="CLU_1097076_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981766" evidence="2">
        <location>
            <begin position="27"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="24277" checksum="132C7053B2039753" modified="2009-10-13" version="1" precursor="true">MFGMKTLVVGGGAVALLWMMNSHASAGDLVDNVQNGASTVSNGYQSVSTGVSNVQSALNGVSTSLNGVSTGVSGVSGVSTSVNGVSTSVGGASTSSTSSTSGSGLSGPAVELNPSAAKPGQQVLITVPTCIQPETGTATSSVFANNGSVSLTRNPKGAGLAGTATITSTAQNGQWSVNVTCGTGSASLNGVTSITIYGGTNPTPTNPPKAGGGGSVMKGDMGMTAGGIALVAGGVGYGLWTMRRRGADGTHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVM9</accession>
    <name>C7PVM9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0433"/>
    <dbReference type="EnsemblBacteria" id="ACU69385">
        <property type="protein sequence ID" value="ACU69385"/>
        <property type="gene ID" value="Caci_0433"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0433"/>
    <dbReference type="HOGENOM" id="CLU_131335_0_0_11"/>
    <dbReference type="OMA" id="VAVQHNS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14375" checksum="28254558F4C75E50" modified="2009-10-13" version="1">MDVVGEALPAIISAVRTYGDTVLTAGEQAAASGTVSLGRRLLQKLFGGAPKPVVFEDAVANLAAAPESDDAVAALRLQIGNVLARHPELRDEIAAMLPHQTGNTVSGDGSANAGRDQNISASGGTAVGVLNIHPSSPDPTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVU7</accession>
    <name>C7PVU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786632.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2421"/>
    <dbReference type="EnsemblBacteria" id="ACU71339">
        <property type="protein sequence ID" value="ACU71339"/>
        <property type="gene ID" value="Caci_2421"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2421"/>
    <dbReference type="eggNOG" id="COG0595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031965_1_0_11"/>
    <dbReference type="OMA" id="HGYHPDW"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Lactamase_B" evidence="3">
        <location>
            <begin position="15"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="430" mass="46266" checksum="B4877CBDEBC57E8B" modified="2009-10-13" version="1">MAATVEFWGGVGVIGSSKVLITEGDHRVLLDFGLDIPRGTDLFRPPVVPRPHRYLADRLRVGAAPRLPGVYDPAMLEPGDPLAQDGPATAVFVSHAHIDHCGLVGALRPGIEVHAAPETVAVMRALTAAGDGLPGGDPDWRPLAEEESACFGPLTVERVTVDHDVPGASGYLVTTSDGVLAFTGDIRFHGRAPERAWRLAERAAGCEMFVTEGTALGLPVFPGPVRTEQDVVRDFAAALEEARGDLVLLAMYPRDLERVAEFIEVAGAAGRKIVWGEAVAVFLRELGVQDVLAFSEVGLQALKDDPGGFVYQPDLRDLRGIPDLADLPVGERTVWLHANGEPLGPFESRWPLFTEWLDVLGIPLRRIGSFGHATADDLHTLVHRVAPRTVVPIHTDAPERLHPVAGPVRLLPVLAQSYDLGGHPIERTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVW5</accession>
    <name>C7PVW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786650.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2439"/>
    <dbReference type="EnsemblBacteria" id="ACU71357">
        <property type="protein sequence ID" value="ACU71357"/>
        <property type="gene ID" value="Caci_2439"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2439"/>
    <dbReference type="HOGENOM" id="CLU_2680929_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="74" mass="8185" checksum="82F4C4A297AA8A1F" modified="2009-10-13" version="1">MFMRLIEIGLIVLAGWALFGRNRLTDSVRNVRKSARIMKSEMQAAADDVELPEDRTIPGTIVDGGAQRADKAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWG2</accession>
    <name>C7PWG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794971.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6388"/>
    <dbReference type="EnsemblBacteria" id="ACU75242">
        <property type="protein sequence ID" value="ACU75242"/>
        <property type="gene ID" value="Caci_6388"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6388"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_81_11"/>
    <dbReference type="OMA" id="MREWFPM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="23"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="315"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="482" mass="52324" checksum="81AEB013D3526882" modified="2009-10-13" version="1">MTAAERVGGSGPCSVEELRGLFLFEKLSDEQLNWLCEQGTVHTYAPGQVYAEGDAALWFYVLLEGTVVMSRRVGTDDVEVIRTSQRGVYAGAFQAYLDEKVPQTYRNSLAITVPSRFFVLSAQSFSTLMHEWFPMAVHLLEGLFFGTQIQQQLVGGRERLLALGVLSAGLTHELNNPAGAALRASSALREGVADARTALGEIAAEPEHAPDLQTLVALLNRAVEQAARQKTSALGLSPLAVSDLEDSTADWLDDQGVQDGWRFAPTFVQAGLGVADLDEIARTVDEHVLPAVLSWLSRILDVESLTVEIEEATVRISALVGAAKQYSQLDRAPQQESDIHTLLDSTVTMLAGKIPDGVRVVKDYGADLPKIPVYPAELNQVWTNLIDNAVAAMDGSGTLTIRTVLDLDRLVVEFEDTGPGIPEEIQGRIFEPFFTTKPVGQGTGLGLDISWRIVVGRHHGDLSVESVPGDTRFLVRLPVKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT0</accession>
    <name>C7PWT0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8364"/>
    <dbReference type="EnsemblBacteria" id="ACU77187">
        <property type="protein sequence ID" value="ACU77187"/>
        <property type="gene ID" value="Caci_8364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8364"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_3_0_11"/>
    <dbReference type="OMA" id="NRDSELM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="16"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="23192" checksum="84946E149F345822" modified="2009-10-13" version="1">MTSSAPAPTPASAPAPIVRCDMAISVDGFTTGLEAQKPPFRDDRFHRITSWVFDGEDATKLMHAERVDNTGAYVMGRRMYDSAGDYWSVESPYRTHVFIVTHRPQENIELKDGTVFHFVTEGGVPAAIAAAKAVCPPGKRVHLSGGAAVVQQALAADLVDELHLHITPVLVGQGNRLFDGLPDRMTELEATRVIEAESGVMHLSYRIPRSQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT3</accession>
    <name>C7PWT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796915.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8367"/>
    <dbReference type="EnsemblBacteria" id="ACU77190">
        <property type="protein sequence ID" value="ACU77190"/>
        <property type="gene ID" value="Caci_8367"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8367"/>
    <dbReference type="eggNOG" id="COG2318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097062_0_0_11"/>
    <dbReference type="OMA" id="RTWEHSD"/>
    <dbReference type="OrthoDB" id="2047691at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007061">
        <property type="entry name" value="DUF664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04978">
        <property type="entry name" value="DUF664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="22251" checksum="A929DD3B1A884D49" modified="2009-10-13" version="1">MTDDAAKLFLHQRLKKIREVLIWKLDGLSEYDARRPMTATGTNLLGLVKHAATWEARYFGQVFGRPFPEPLPRWQDSDGSDLWVTEDETRAQIIGFYQRVAAHADATISELPPDAPGHVPWWPRPDIDLFTIVVHLLDDLTRHAGHADILREQIDGRTGVAAEHEETSDAAAQAARWERIEQAAKAAERIQSGGRATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX13</accession>
    <name>C7PX13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796995.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8447"/>
    <dbReference type="EnsemblBacteria" id="ACU77270">
        <property type="protein sequence ID" value="ACU77270"/>
        <property type="gene ID" value="Caci_8447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8447"/>
    <dbReference type="eggNOG" id="ENOG50336CV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136814_0_0_11"/>
    <dbReference type="OMA" id="LTTERHD"/>
    <dbReference type="OrthoDB" id="1868066at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="164" mass="18342" checksum="8C1DA89A51DCC113" modified="2009-10-13" version="1">MATTSESVPFSELIQHPRETTSRLDRAETLRLVRRNQPDLMLVAAERAERDAEIFDVTTRLLVGIIAREPAPEVLRSSVLGVFAWTRFLPDAAVDEFLAELVGVARASAEIRNLRPVAQVIVEWQHTAEIHADPELYRMLTREFSPEDDFGPVDVPAQPGQEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX33</accession>
    <name>C7PX33_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha amylase catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8467"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77290">
        <property type="protein sequence ID" value="ACU77290"/>
        <property type="gene ID" value="Caci_8467"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8467"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_2_3_11"/>
    <dbReference type="OMA" id="FHYADID"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="18"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="60514" checksum="31EEFA0A990414A9" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY28</accession>
    <name>C7PY28_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4627"/>
    <dbReference type="EnsemblBacteria" id="ACU73488">
        <property type="protein sequence ID" value="ACU73488"/>
        <property type="gene ID" value="Caci_4627"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4627"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_2_2_11"/>
    <dbReference type="OMA" id="VLFHNNA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981339" evidence="2">
        <location>
            <begin position="21"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="101"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29104" checksum="FA3A110FB180A6D7" modified="2009-10-13" version="1">MLLGGCASTGKPVAVRPAGATTPTAGGSPRSRPTTGGAPFPGQSPASPGTSPAGGDTSTAPGDSHSNGSAPPDSSPPPSATGQDPPPPAGHPQFYVHEGDKAIALTIDDGPSSKYTPQVLALLAQYKIPATFCMIGQNAAQHASLVAEVSAAGHLVANHTWTHPNLAKMSEAQVTAEIERTNDAITKGGARQPVLFRAPGGNWSPTVFSVCAKLGLRALDWSVDPRDWSRPGTDHIVQTVMGHTHTGSIILEHDGGGDRSQTVAALQRFLPQLLEAGYKFVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY70</accession>
    <name>C7PY70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6511"/>
    <dbReference type="EnsemblBacteria" id="ACU75360">
        <property type="protein sequence ID" value="ACU75360"/>
        <property type="gene ID" value="Caci_6511"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6511"/>
    <dbReference type="eggNOG" id="COG4221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2166446_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="110" mass="11199" checksum="B036D3CF62101C10" modified="2009-10-13" version="1">MPAQIAAPDGRLYVFDRMPHHARSAADPGVGRASARLFAKEGAKVVVAGRSHERGDELIAEINDSGGTAPFVEPDVEIAAPAGVVAGGVRDIVCVGRTLGTGLPSAVGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC0</accession>
    <name>C7PYC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6564</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6564"/>
    <dbReference type="EnsemblBacteria" id="ACU75410">
        <property type="protein sequence ID" value="ACU75410"/>
        <property type="gene ID" value="Caci_6564"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6564"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_8_3_11"/>
    <dbReference type="OMA" id="STWYLVP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="375" mass="39748" checksum="25B4694DDD015B22" modified="2009-10-13" version="1" precursor="true">MRTVTNSLPWRLVVRLLRTVVRWMRAMVLKEFLELRRDRRTMVMIVALPLLLLVVFGYAANFTVTSIDTQVLGPQAAKVAAELKAPFHVTKIDPSAGAEQGVDALRSGDAGAVVVTGEAPGPSTVQIDGSQLFSAQSASATARASGGALVPQVLFNPELKTSWVMVPALVGMIMAFIGTIITAIGLVRERQTGTLEQLAVMPFKPSDVIAGKIIPYFVLAAFDMVLVTALGCLLFGVPFAGNVLVFALGAALFLFTTLGIGVLISTVSQNQGQAMQLALMTMMPQILLSGMIFPLSAMAAGVRWIGYLLPLTYFNRISLGVMLRDAPLSSLAFPLGILALMAVVVFTAAVLRFRRDLAPAKPHAAKVPAAAGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL4</accession>
    <name>C7PYL4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-dependent protein deacetylase</fullName>
            <ecNumber evidence="4">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cobB</name>
        <name evidence="6" type="ordered locus">Caci_8513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sirtuin family. Class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8513"/>
    <dbReference type="EnsemblBacteria" id="ACU77336">
        <property type="protein sequence ID" value="ACU77336"/>
        <property type="gene ID" value="Caci_8513"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8513"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_2_11"/>
    <dbReference type="OMA" id="RRHYWAR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034979">
        <property type="term" value="F:NAD-dependent protein deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006476">
        <property type="term" value="P:protein deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01967">
        <property type="entry name" value="Sirtuin_ClassII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026587">
        <property type="entry name" value="Sirtuin_class_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="249"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="275"/>
            <end position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="32995" checksum="51E41780E76067E1" modified="2009-10-13" version="1">MELRGNGAYAGVVRTRPTLTWEPPSGEVFARTTSLDAMVDLVAGRGVVVLSGAGLSTESGIPDYRGKSGALRRHTPMTYEDFAGSAQARQRYWARSHLGWRAMAGAQPNVGHRAVAALRASGHVDGVITQNVDGLHQAAGTLPEVVDLHGSLDRVICLTCGVFSERTELERRLNEANPVFDGVAARINPDGDVELAEDAVRRFRSVDCDSCGEGVLKPDVVFFGENVPKARVERCKELVDGAAALLVLGSSLTVMSGLRFVRRAAEAGKPVVIVNQGLTRGDRYASERIEAPLGAALVELVGRVGAAADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM3</accession>
    <name>C7PYM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797070.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8522"/>
    <dbReference type="EnsemblBacteria" id="ACU77345">
        <property type="protein sequence ID" value="ACU77345"/>
        <property type="gene ID" value="Caci_8522"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8522"/>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036302_1_1_11"/>
    <dbReference type="OMA" id="HMFVMGR"/>
    <dbReference type="OrthoDB" id="311112at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007795">
        <property type="entry name" value="T7SS_EccB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044857">
        <property type="entry name" value="T7SS_EccB_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40765">
        <property type="entry name" value="PTHR40765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05108">
        <property type="entry name" value="T7SS_ESX1_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03919">
        <property type="entry name" value="T7SS_EccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="510" mass="52211" checksum="957747293291B756" modified="2009-10-13" version="1">MAIQSRRDQVLAYRFLLRRRHATLLSGDPDSPEAPLRKLSTATFASIMLATLMAAGAGVLGALSPGHSASWRDPNVVIVVKETGSRFIYDPTPAPQGSPPALHQILNYTSARLLLSSSGWKTVSVSEKSLADTPRAADIGIVGAPDDLPSTGNVRGGPWTVCSLPGANAQNQPVTLTRLTIGTSGDPTDGSPLGDQGLVVQAGGGYWLVWHGHRFQIGDPAAPQNGDTPARVLTFLGWSPGQALSVSQAWLDSLSALSPLRAPHLDNGTPPGTVSVTGQKVSVGQLVRIPAQNGVAERLFVVTVKGFVQIDNLQYQLLATSTDLKPMDGTPQDVGNGQSGDASTVSSGDGQWPQTPPQLVNASAAGPSTACATTAGTDGSMTVSVAPATTGQPTCYRLPPQAPSATYLADCIAVAPGTAAVVRSRTNTGIAAAEYLVSGNGEYTAKDSLGPDPATTLKALGYAAVTPIAVPQTMLDLLPDGPALTPDAARQAVVPPPPGPAPTSASGSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM8</accession>
    <name>C7PYM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797075.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8527"/>
    <dbReference type="EnsemblBacteria" id="ACU77350">
        <property type="protein sequence ID" value="ACU77350"/>
        <property type="gene ID" value="Caci_8527"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8527"/>
    <dbReference type="HOGENOM" id="CLU_1728048_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16906" checksum="5EB23AF70CFF56BC" modified="2009-10-13" version="1">MSELPRFATAQSVAQLKTLYSQLLDEADDLKARVNDFKERSAAVEGRARTPEDDIRVTVGPHGDLRTLEIDPRAYRKLGPTELSQEIVELCEKAHRNAGEQVGDLMRSVLGRDFDVEAHLRGDSQPPRPSRLPSSALDMGEWLDRLKEGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ74</accession>
    <name>C7PZ74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding region ATPase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0695"/>
    <dbReference type="EnsemblBacteria" id="ACU69630">
        <property type="protein sequence ID" value="ACU69630"/>
        <property type="gene ID" value="Caci_0695"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0695"/>
    <dbReference type="eggNOG" id="COG0326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028672_0_0_11"/>
    <dbReference type="OMA" id="WTRPAQV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="643" mass="68918" checksum="22B7EA0672733442" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA7</accession>
    <name>C7PZA7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular ligand-binding receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2648</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2648"/>
    <dbReference type="EnsemblBacteria" id="ACU71564">
        <property type="protein sequence ID" value="ACU71564"/>
        <property type="gene ID" value="Caci_2648"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2648"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_6_0_11"/>
    <dbReference type="OMA" id="MEFTGAR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982637" evidence="2">
        <location>
            <begin position="30"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="54"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="41257" checksum="28B80B6D8A475B25" modified="2009-10-13" version="1" precursor="true">MRTINRVRVGAVVVAAVLALSACAGSSSKSGNTGSSTSAGSSSSTGSNRTKPTLEIGVQGPLSGAYQALGLNIDWGAKLAVQEENAKGDLPFNLAIKESDDQGDQSKGATAAQLLIQDPKVLGVVGPAFSGPTAAAGALYSSANLVAVSVATRPSLTSSGFKTFFRVVANDSVQGPAAADYIAKVLKATNVYVVDDKSQYGQGLSQATVAELKKDGVKVETDSAAAGTQDYSPLASKVAASGAQAMYYAGYYADAGVFAKALKGVSYTGTMLAGDGSKDPNFIATAGADAAAGWQFTCPCFDPTTDPKYATFTADYKKLANAAPGTYSIEGYDSANTIISVLKSLNTANPTRQAVADGVGKVDYQGLSKEIKFSPTGDVSGTSIYVYQVKGGAITLLGDISKLIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZL0</accession>
    <name>C7PZL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793254.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4664"/>
    <dbReference type="EnsemblBacteria" id="ACU73525">
        <property type="protein sequence ID" value="ACU73525"/>
        <property type="gene ID" value="Caci_4664"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4664"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="AFTKGTN"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32626" checksum="44362742F5719102" modified="2009-10-13" version="1">MSQPTHHTAPTADVIVVTGASSGFGNLAARALARAGHTVYAGMRATDGRNAARVAELAQLSADEGLDVRGIEMDVQDQASVDAAIARIAEEQGRLDVVVHNAGHMVLGPAEAFTPEQLAELYDINVLSTQRVNRAALPLMRRAGSGLLVWVASSSTRGGHPPFLAPYFAAKAGMDALAESYAAEVIRYGIDTVIIVPGAYPSGTNHFAHAGQPADPDRAAEYDAAYGELRDQMADRLTALFPAGRTVDEVADAIVEAVALPAGQRPFRIHIDPSRDGSDVVSTVSDRIRAEFYHRIGIADLLTDHASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP6</accession>
    <name>C7PZP6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TM1410 hypothetical-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793290.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4700"/>
    <dbReference type="CAZy" id="GH114">
        <property type="family name" value="Glycoside Hydrolase Family 114"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73561">
        <property type="protein sequence ID" value="ACU73561"/>
        <property type="gene ID" value="Caci_4700"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4700"/>
    <dbReference type="eggNOG" id="COG3868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051214_3_0_11"/>
    <dbReference type="OMA" id="STGAWED"/>
    <dbReference type="OrthoDB" id="1327691at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980483" evidence="1">
        <location>
            <begin position="42"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_114" evidence="2">
        <location>
            <begin position="54"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="31446" checksum="38056BC055C96605" modified="2009-10-13" version="1" precursor="true">MTLTPTAKRITSAAAGLALVAAATAALAPSASATPALPSPAACNGCWHPSLQTSWNWVLSTVPTAPFRNVQMYDVDGFNNTAANVSALHSAGIKAVCYLSAGTYENWRPDASQFPAAVLGSGNGWPGEKWLDVREIQKSNSALRKIMDARLDMCHQKGFDMVELDNVDGYSNSTGFSLTAADQLYYNATLANDSHARGMSVLQKNDNEQIPQLLPYFDGALNEQCNQYKECTTAQNGDYGYDQYVAKGKPVFQAEYKLATSSFCSKDNANNFNGVRFDIDLDDKTFQACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZX3</accession>
    <name>C7PZX3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lysozyme</fullName>
            <ecNumber evidence="4">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6620"/>
    <dbReference type="CAZy" id="GH25">
        <property type="family name" value="Glycoside Hydrolase Family 25"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75466">
        <property type="protein sequence ID" value="ACU75466"/>
        <property type="gene ID" value="Caci_6620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6620"/>
    <dbReference type="eggNOG" id="COG3757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044973_4_1_11"/>
    <dbReference type="OMA" id="IDWTHRY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008270">
        <property type="entry name" value="Glyco_hydro_25_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00953">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982732" description="Lysozyme" evidence="5">
        <location>
            <begin position="36"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="30613" checksum="B5337B8DB0650F52" modified="2009-10-13" version="1" precursor="true">MSSRIHKIMAGHTRLLTAGVLAAGLALAATGPATAASRALPAGSTIPLGDGYMGVGYVQDAKQFTPDTRQVTAAAVTPDATWSPAGIDVSHYQGTINWSSVKSAGISFAYIKATEGTTYTDPQFSANYLHAYNAKVIRGAYHFAQPGSSSGGAQADYFAAHGGAWSKDNLTLPGMLDLEGGCYGLSTTSMRNWILAFYNEYKAKTTRDVVIYTSPSWWNTCTGSWSGMSAKSPLFVADWTSAANPTIPAGFPYATIWQYTNSGSVSGISGAVDRDRFNGGSARLLALANNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0F5</accession>
    <name>C7Q0F5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_8673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8673"/>
    <dbReference type="EnsemblBacteria" id="ACU77488">
        <property type="protein sequence ID" value="ACU77488"/>
        <property type="gene ID" value="Caci_8673"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8673"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_2_0_11"/>
    <dbReference type="OMA" id="AYNFLIV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982664" evidence="8">
        <location>
            <begin position="21"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="9">
        <location>
            <begin position="231"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU77488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="657" mass="67992" checksum="F3F55D4868B5C450" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0I2</accession>
    <name>C7Q0I2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797239.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8700"/>
    <dbReference type="EnsemblBacteria" id="ACU77515">
        <property type="protein sequence ID" value="ACU77515"/>
        <property type="gene ID" value="Caci_8700"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8700"/>
    <dbReference type="eggNOG" id="COG2813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_0_0_11"/>
    <dbReference type="OMA" id="ICAHYLH"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="217" mass="23384" checksum="1BCCC0E05418AECC" modified="2009-10-13" version="1">MHSETTTDSATFWEKHYARFDPSWGTKPNVVLKDLLATFAPPPGTALDLGCGHGGDAIWLATQGWDVTAVDVSQTALDRVAEGAWAVSAAERVHPVRHDLAQTFPAGDFDLVCATYFHTPIAIPRTEVLRKAARAVAPNGLLIVVEHASVAPWSWQAGQDVSFPAPEEVLASLALDDLWRVERCDAPQRTATGPQGQKATVTENIIVLRRTAIAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Q9</accession>
    <name>C7Q0Q9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784982.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69687">
        <property type="protein sequence ID" value="ACU69687"/>
        <property type="gene ID" value="Caci_0752"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0752"/>
    <dbReference type="HOGENOM" id="CLU_1802603_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025326">
        <property type="entry name" value="DUF4232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14016">
        <property type="entry name" value="DUF4232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="14727" checksum="F119687344EABDCD" modified="2009-10-13" version="1">MPSGTWRDVPDSEGAGHVAADIAFQNTSDHTCTVSGFPAVSLLASNDHPLPTNVLKNSSASVTTVKVAPGAWIHAEMRYSPNVPGPGEPENGQCEPMTVHALAQLPGDTAWARVTLGNPTAVCEKGELQTKPFVSGQASPAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1P5</accession>
    <name>C7Q1P5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ordered locus">Caci_6751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795325.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6751"/>
    <dbReference type="EnsemblBacteria" id="ACU75596">
        <property type="protein sequence ID" value="ACU75596"/>
        <property type="gene ID" value="Caci_6751"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6751"/>
    <dbReference type="eggNOG" id="COG0499">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_2_1_11"/>
    <dbReference type="OMA" id="CLHVEAK"/>
    <dbReference type="OrthoDB" id="522981at2"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="244"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="273"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="52476" checksum="335239433F847F15" modified="2009-10-13" version="1">MKHHLKEIGGLRFAVADLDLAESGRLQIQLAEHEMPGLMALRAEHAAAQPLRGARIAGSLHMTVQTAVLIETLAALGAEVRWVSCNIFSTQDEAAAAVVVGPDGTPGKPTGTSVFAWKGETLEEYWWCTRQLFDFGDGRGPDLLVDDGGDATLLVHLGAEYETAGGVPEPEPGDHEERRQILRLLADSLAEDDRRFTRIAAGLRGVSEETTNGVARLYKLAREGRLLFPAINVNDSVTKSKFDNKYGIRHSLPDGLNRATDVMLGGKVAVVCGYGDVGKGAAEALRGQGARVVITEIDPINALQAAMDGFQVARLEQVVADGHIFVTATGGTGAIGVEHLARMRHNAIVGNVGHFDTEIDLAGLAAHPGVTKTEIKPQVHQWTFADGHAVLVLSEGRLFNLGNATGHPSFVMSASFANQVLAQIELFTQPDRYQDAVYRLPKHLDEKVARLHLDALGVQLTELSAEQAEYLGVEIEGPYKAEHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y8</accession>
    <name>C7Q1Y8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795417.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6848"/>
    <dbReference type="EnsemblBacteria" id="ACU75689">
        <property type="protein sequence ID" value="ACU75689"/>
        <property type="gene ID" value="Caci_6848"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6848"/>
    <dbReference type="eggNOG" id="ENOG502Z84P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060481_0_0_11"/>
    <dbReference type="OrthoDB" id="1355200at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024414">
        <property type="entry name" value="Uncharacterised_PrgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12666">
        <property type="entry name" value="PrgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="30717" checksum="5C71FB3307DF548C" modified="2009-10-13" version="1">MSGDNYSGTAKIPQDVSRPDKILFGATARQAVILSAAAVAEWLSWLGLRSTVPPLMFAVPAGLFLLVLGIAVSAERDGIGVDRLLLAALKQRLSPRRLVMAPEGVDEPPEFLRTALHTQRETTPSTLNLPAQGVISGGVVDLGSDGAAVLATASAVNFTLRTPAEQELLVTGFARWLNSLTGAGQITSRTTPTNLTAEARTLRTSAPTLPHPLLESAALGHADFLDQIGDSREVLHRSLLITAREQELAHMPRAQQRLNGAVSALSAAEVDVAPLDAAPAATALAAALDPDANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q255</accession>
    <name>C7Q255_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797316.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8777"/>
    <dbReference type="EnsemblBacteria" id="ACU77592">
        <property type="protein sequence ID" value="ACU77592"/>
        <property type="gene ID" value="Caci_8777"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8777"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029927_4_1_11"/>
    <dbReference type="OMA" id="VCELWRS"/>
    <dbReference type="OrthoDB" id="710201at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="469" mass="50012" checksum="143ADA2BABDDFCC1" modified="2009-10-13" version="1">MEGHRGPREPNRRLAELIAEAGCSNAGLARRVNLAGAELGLDLRYDKTSVARWLRGQQPRATTPALIAEAVGRKLGRPVTVEEIGMVDERDGSSSLALNLAADTQEAIAVAAGLWRADSAGREQLRAASFAVTAMVGPSRDWLIMPEDPVVARGMAAAKNGHAPLRVGLSDVAAVRAATDSFRALDHRFGGGHVRVLAVRYLDGVVTELLRGTYPERVGRQLFAAAAALTELAGYLACDTGRLGLAQRYYIQALRLSQAAGDRAHGGHILSAMSHLANSLGAPRETVQLARSADEGARGTASPHVRAEFFCAEARGYAAMRDRRAAEQALGRASDELERSGGDAPVWSSYFDHHYIADAAAACHRDLEQPRQAAEQAALALAGFGLDKTRRRVLNLFTLASARVQGGEVEAGCAAATEAVKLSGRARSARAVEALHDFDRRLDPYAAVAATREFRSLIALRRPGEPINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2B1</accession>
    <name>C7Q2B1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797372.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8835"/>
    <dbReference type="EnsemblBacteria" id="ACU77648">
        <property type="protein sequence ID" value="ACU77648"/>
        <property type="gene ID" value="Caci_8835"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8835"/>
    <dbReference type="eggNOG" id="ENOG50343BG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1406509_0_0_11"/>
    <dbReference type="OMA" id="DSPTHAN"/>
    <dbReference type="OrthoDB" id="1645460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982719" evidence="2">
        <location>
            <begin position="35"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="18834" checksum="9D62AB5888DAFE9E" modified="2009-10-13" version="1" precursor="true">MTSRRTSLVRTGATLAVAALLAAGCSSSKSSPSASGTTAGSSSTSSSAADTSSPSTSASSSASGGQPSDVAGATQAVKDAYNKFFDNSISTATKAAMVQNAGQVQALLTALAAAANGEKSSIQVNTVTFDSPTHANVDFAILLNGQPALPHASGDAVYDSASGNWQVSDATLCKLAGITPGVNPTVLKAAGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P7</accession>
    <name>C7Q2P7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2880"/>
    <dbReference type="EnsemblBacteria" id="ACU71789">
        <property type="protein sequence ID" value="ACU71789"/>
        <property type="gene ID" value="Caci_2880"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2880"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_4_4_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="28"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15701" checksum="D54ADB2D055A8880" modified="2009-10-13" version="1">MLLTAIPQDRPVADSPLYDEITLPRVLQSVRDTRHWLDATLAGWDVPADTVENATLVVSEITTNALVHNAGLGDMIVTAAWWHGHLRITVSDPDLQIPVPDLADDEHGRGLLIVGDLATRWGRTKTRTGKITWFELTAEVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2T6</accession>
    <name>C7Q2T6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787121.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2919"/>
    <dbReference type="EnsemblBacteria" id="ACU71828">
        <property type="protein sequence ID" value="ACU71828"/>
        <property type="gene ID" value="Caci_2919"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2919"/>
    <dbReference type="HOGENOM" id="CLU_1709935_0_0_11"/>
    <dbReference type="OrthoDB" id="1950005at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046193">
        <property type="entry name" value="DUF6221"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19730">
        <property type="entry name" value="DUF6221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16860" checksum="ED6AB5BB5AB64FD6" modified="2009-10-13" version="1">MTDIVEFIKAQMAVDEQLALATTPVPVPGSWRAAQDKHAADDAPLSLIQGRDEDEFHDPDNIGYSYGNPVIVHAADWQDEAEANLRHIERHDPASVLADVKAKRELLRHAAELREVAALTETWLLMDAAVGIERALVAAYAGRPGFKTEWSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U3</accession>
    <name>C7Q2U3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6292 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787128.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2926"/>
    <dbReference type="EnsemblBacteria" id="ACU71835">
        <property type="protein sequence ID" value="ACU71835"/>
        <property type="gene ID" value="Caci_2926"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2926"/>
    <dbReference type="eggNOG" id="ENOG502ZHBN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144844_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046259">
        <property type="entry name" value="DUF6292"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19809">
        <property type="entry name" value="DUF6292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6292" evidence="1">
        <location>
            <begin position="11"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14358" checksum="51BAE218DACD2671" modified="2009-10-13" version="1">MFVKPMPHDGYINEVAYQLTQLGHEPTQQWTTSPDGEQLDGVIVFDDADPALWPDHVWLGWDQHNGWALCDNGTRALFPLDLDVYAAPGAVAVRAADRLTGRQDTDVDEDWDGAAALAEAVRAWEKEGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3B6</accession>
    <name>C7Q3B6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4992</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4992"/>
    <dbReference type="EnsemblBacteria" id="ACU73852">
        <property type="protein sequence ID" value="ACU73852"/>
        <property type="gene ID" value="Caci_4992"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4992"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="MSLHNWP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="67"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="31288" checksum="368370DDE182A2B9" modified="2009-10-13" version="1" precursor="true">MRNRRKSAVGAAYAVPTAVVVTLFFLIPLGLVAVMSVDHWPLLGHATPNFPANYTDMADNTLLHQAVFFTLKYTVVITVVLFAVAFGLALLVQNPQPGVGALRTAFFLPTAVGFATASLLFLGMLSNEIGPVNPLLKDFGLIDKPVDWITGSPGTALTSTVGLVTWRFAGFNMLILLTGLQAIPTEIYEAARVDGASAWQSFRRITLPLMRPTIALVLIMMITGSLLAFDQFYIMTQGGPDNSTTSVVMVIVRQAFVKFNLGSAAAVSVAALGVLIVLNVFQLSVLRRRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3D6</accession>
    <name>C7Q3D6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6861"/>
    <dbReference type="EnsemblBacteria" id="ACU75701">
        <property type="protein sequence ID" value="ACU75701"/>
        <property type="gene ID" value="Caci_6861"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6861"/>
    <dbReference type="HOGENOM" id="CLU_2615524_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="7943" checksum="2FD6EA2F2282FBFA" modified="2009-10-13" version="1">MPTTAPDPRTPNVGPSQIPRGPLPGAAPALPPDACVNFNLIDGRVACLSVPIGITEADAAFILAVIQAHVTAVARRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E4</accession>
    <name>C7Q3E4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6870"/>
    <dbReference type="EnsemblBacteria" id="ACU75709">
        <property type="protein sequence ID" value="ACU75709"/>
        <property type="gene ID" value="Caci_6870"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6870"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="ARMAGEF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="30"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="42086" checksum="CFCA0A9FE841B1DC" modified="2009-10-13" version="1">MESSTPAAPGPGPGSPPAAGRRPDSQLRELTLRGVTRDYGEHTALHPLDLTVHGGEFVALLGPSGCGKTTALNCLAGLLPLSGGEIALDGRRVDTLPPEKRGFGMVFQNYALFPHLTVRANVGFGLKMRKTGKAEIGRRVDAVLRLVRLTEQAHKHPGQLSGGQQQRVAIARAIVLEPPLVLMDEPLSNLDAALRLQMRGEIRRIHQEFGLTTVYVTHDQEEALSLADRLVVLREGRVSQIGTPADLYETPADPHVAAFMGYRNLLRLEAVTADSQGVLARGRGLELRGTPVADRVLDLREPVVVAIRPENVHLAEGGAPADLTAVAEIVEYHGRQFHVEARTDGGDRVYFKTATRVHPNDPVSLTIPADRALVFRDPQGADLSANQGAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3E7</accession>
    <name>C7Q3E7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795440.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6873"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75712">
        <property type="protein sequence ID" value="ACU75712"/>
        <property type="gene ID" value="Caci_6873"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6873"/>
    <dbReference type="eggNOG" id="COG3345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030937_0_0_11"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981398" description="Alpha-galactosidase" evidence="6">
        <location>
            <begin position="48"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="7">
        <location>
            <begin position="458"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="589" mass="62775" checksum="2F2023F26427DCD3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3F9</accession>
    <name>C7Q3F9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75724">
        <property type="protein sequence ID" value="ACU75724"/>
        <property type="gene ID" value="Caci_6886"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6886"/>
    <dbReference type="HOGENOM" id="CLU_3306713_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="39" mass="4340" checksum="8A1307C9D9F571E9" modified="2009-10-13" version="1">MLALLRVFPALLARARAIARADLKKFSKARLSSISRVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3H8</accession>
    <name>C7Q3H8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6906"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM61">
        <property type="family name" value="Carbohydrate-Binding Module Family 61"/>
    </dbReference>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75743">
        <property type="protein sequence ID" value="ACU75743"/>
        <property type="gene ID" value="Caci_6906"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6906"/>
    <dbReference type="eggNOG" id="COG2273">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_435277_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="53"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="1">
        <location>
            <begin position="325"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="628" mass="66293" checksum="96C50E1504E48204" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3L4</accession>
    <name>C7Q3L4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6948"/>
    <dbReference type="EnsemblBacteria" id="ACU75779">
        <property type="protein sequence ID" value="ACU75779"/>
        <property type="gene ID" value="Caci_6948"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6948"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_511630_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="90"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="532" mass="56297" checksum="5E0A3BCDEA65D0CB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3L8</accession>
    <name>C7Q3L8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795511.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6952"/>
    <dbReference type="EnsemblBacteria" id="ACU75783">
        <property type="protein sequence ID" value="ACU75783"/>
        <property type="gene ID" value="Caci_6952"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6952"/>
    <dbReference type="eggNOG" id="ENOG502ZNKR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2647861_0_0_11"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="76" mass="8323" checksum="58C0BBF017065A4A" modified="2009-10-13" version="1">MHTRKVIIDSTQWISEEPDAAKLVGTIQDAMQNGTVVSLPLLDTARRRFTVIVNGRTVQTVAVDLDMNPAPTEMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q470</accession>
    <name>C7Q470_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ordered locus">Caci_1002</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1002"/>
    <dbReference type="EnsemblBacteria" id="ACU69930">
        <property type="protein sequence ID" value="ACU69930"/>
        <property type="gene ID" value="Caci_1002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1002"/>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_0_2_11"/>
    <dbReference type="OMA" id="HLEGHIY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="30"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="36035" checksum="DDFB95753ED19082" modified="2009-10-13" version="1">MTALKEEPLVLGFETSCDETGIGIVRGNTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVPTVQRALSDAGVALADIDAIAVTAGPGLAGALLVGVAAAKSYALALDKPIYGVNHLAAHICVDQLEHGPLPEGCIAMLVSGGHSSLLFVPDVTGDVQPLGQTIDDAAGEAFDKVARVLGLGFPGGPLIDKAAREGDPEAIAFPRGLTGPRDAPLDFSFSGLKTAVARWVEKRERAGEKISIPDVAASFQEAVVDVLTRKAILACKEQGAEYLLIGGGVAANSRLRVLAEERAAKAGIQVRVPRPKLCTDNGAMVAALGSELVRRGRVPSQLGFPADSSQPVVDVVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4P7</accession>
    <name>C7Q4P7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787309.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3107"/>
    <dbReference type="EnsemblBacteria" id="ACU72016">
        <property type="protein sequence ID" value="ACU72016"/>
        <property type="gene ID" value="Caci_3107"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3107"/>
    <dbReference type="eggNOG" id="COG0307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_2_0_11"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="102"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="102"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="22804" checksum="64EBE66B8090C855" modified="2009-10-13" version="1">MFTGIVEELGRVVALEADGDSARLRVAGSLVTSDAEHGSSIAVNGVCLTVIESGDQAAKAGEFTADVMAETLDKSNLGDLKPGDPVNLERPMKLGARLGGHLVQGHVDGVGVVLERIPGEHWEVVRVSLPSALSRYVVDKGSITVDGISLTVVEAAADSFTVSLIPTTLELTTLGSKGPGAAVNLEIDVIAKYTERLLGLDGAAAGQSESGSAADATSKEVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4X3</accession>
    <name>C7Q4X3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793650.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5061"/>
    <dbReference type="EnsemblBacteria" id="ACU73921">
        <property type="protein sequence ID" value="ACU73921"/>
        <property type="gene ID" value="Caci_5061"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5061"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093180_0_0_11"/>
    <dbReference type="OMA" id="CVDAIQF"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="65"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27300" checksum="689AC9ABD1CC1DE8" modified="2009-10-13" version="1">MSDWPPSAEDFNAWYANMVDHSSGDAIQRRHLGLPAHLLSTSLLTWDGIAEVIEALRLEPGTRLVDLACGRGGYGLEMAARTGATLIGIDFSKEAIAQAAALAQRLGAEAEFRAGDLADTGLPAASVDALVCVDAIQFKPEPATFAEMHRVLAPGGRIALTTWEALDRSDERVTPRIRVVDVQAGLEQAGFVDVEVRERPQWRSAERALWEEAAALDPGDDPALKSLHDEGVRVLPWFDLTRRVLATAGVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5K5</accession>
    <name>C7Q5K5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_9003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797540.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77816">
        <property type="protein sequence ID" value="ACU77816"/>
        <property type="gene ID" value="Caci_9003"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9003"/>
    <dbReference type="eggNOG" id="ENOG502ZEHB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324453_0_0_11"/>
    <dbReference type="OrthoDB" id="1758677at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="23077" checksum="E2F5665E5AE0D78E" modified="2009-10-13" version="1">MPLHEFAGREVVDRTAMVSYGIGRSTLDAAYANRAETGFPEKATREGRTDYWFTDEWETWFAGHQKEKAARLTEVDRSGDPDDLVYAAEAARIIGWKDAAAVRKAVRDGYLPAASPQDYDGRRPRWRRATLWDAADARTGHGSPRSGPRKSRDPKPATAAYASDERVIALKRRIATGDHPQAVDIAAEHHVSTRTAERWLRAATESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W3</accession>
    <name>C7Q5W3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785354.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1134"/>
    <dbReference type="EnsemblBacteria" id="ACU70060">
        <property type="protein sequence ID" value="ACU70060"/>
        <property type="gene ID" value="Caci_1134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1134"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044190_0_0_11"/>
    <dbReference type="OMA" id="RAGRTQW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="35027" checksum="84E139DB9533B9BA" modified="2009-10-13" version="1">MDEIDRRIVQCLLYEGRAPFRRIAEVAEVSQQTVARRYRALRADGAVRVRALPSHGARGEATWFVRIQTRPDATDALAEALAAREDTAYVSITSGGAEIVCQTRTDPGAAGGSVLHRLPRTAQVLAYQAHAVLHMHVGDGTKWLAFDDPLAPDQLDRLRGDAIPAPAPSGLDGALRDSDAPLLTELARDGRASAAELARATGWPETRVSTRLDALLTNGALHIAVDLAYPRFGFAAAAYLWLTVTPGDLTAVGDALAQYPETTFAAAVTGSANLLVTVTCRTLEDLYRYVTARVGALDAVRQVDVVPVLHRLKQAGTHLSDGRLLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q685</accession>
    <name>C7Q685_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787384.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3183"/>
    <dbReference type="EnsemblBacteria" id="ACU72091">
        <property type="protein sequence ID" value="ACU72091"/>
        <property type="gene ID" value="Caci_3183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3183"/>
    <dbReference type="eggNOG" id="COG1533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015525_1_0_11"/>
    <dbReference type="OMA" id="GNTDCYQ"/>
    <dbReference type="OrthoDB" id="979208at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="67"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="370" mass="40140" checksum="A6CCAFF048AA6C9B" modified="2009-10-13" version="1">MRWSGQLISGNTDAGDAEGAEAGSGVVQAGLFAASDTVVRTFDTPGFRGATFYEVRAKSVLNKVPGASPMFGWTINPYRGCGHRCVYCFARQTHTYLDFDAGLDFDTRIVVKVNAPEVVRRELARPSWRHESVAMGTNVDCYQRAEGRYRLMPGIIGALAESGTPFSILTKGTLMLRDLPLLEAAARDVPVSLAMSIGSIDESVWRTVEPGTPSPARRLDAVRTLADAGLGCSVLMAPILPFLTDSPEQLRRTVAAIADAGARSVTPIVLHLRSGAREWYYEWLQATYPRLVPRYRALYRNGSYAPSWYQDRITSAVREYAKAYGLVRPKASGDGGGGGQGGSFRNTAKPTAPAAEIQPALWDDEEVSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7A0</accession>
    <name>C7Q7A0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785482.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1263"/>
    <dbReference type="EnsemblBacteria" id="ACU70188">
        <property type="protein sequence ID" value="ACU70188"/>
        <property type="gene ID" value="Caci_1263"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1263"/>
    <dbReference type="eggNOG" id="COG3305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093816_0_0_11"/>
    <dbReference type="OMA" id="FHYDLDH"/>
    <dbReference type="OrthoDB" id="1438626at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021125">
        <property type="entry name" value="DUF2127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09900">
        <property type="entry name" value="DUF2127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="32462" checksum="CFFBB55619997165" modified="2009-10-13" version="1">MRDWNRRHCARRGHETYAPVGSGLETELAARLRVETVHGPAWRCLRCGDFVIGEPTTGSGPADEAPIVPRGKALRDLFILRLLAVERVIRGVVILLIAWAVWKFGSSQNAVQRLFESDLSAFKPFANHFGWDVEHASIVERIRKTFDYKPKTIHTVALLLGGYALLETVEGVGLWLAKRWGEYLTAVGTSIFLPLEIWDGYTKIHEHKSYILAICTFAINVGAVVYLLLTKRLFGIRGGGEAFEAAKHADALMTVELAACNRDLPEPRSALSETVVLNAPALSDPALTDPAPGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7D7</accession>
    <name>C7Q7D7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Membrane bound O-acyl transferase MBOAT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_1300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1300"/>
    <dbReference type="EnsemblBacteria" id="ACU70225">
        <property type="protein sequence ID" value="ACU70225"/>
        <property type="gene ID" value="Caci_1300"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1300"/>
    <dbReference type="eggNOG" id="COG1696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025255_4_1_11"/>
    <dbReference type="OMA" id="IIWGAWH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU70225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="469" mass="51276" checksum="7463EC98F8F7A5C3" modified="2009-10-13" version="1">MQFALFFAVVLPLSWALMPRQRLWRPFILAASYYFYAAADWHYVLLLAGSTVVNQTAATVIARRSSARIRKAALITAITLDLGTLGVFKYLDFFSDSISSSLGLSLGLLHLVLPVGVSFYTFQAISYVVDVHRGRTPLAKPLDYAIYASFFPHLVAGPIVRAAEFVPQLSSPRDPNSIPAGRAFGLIAGGLVKKMVVADMIGTKLVEPVFGTPQAHNGTETLMAIYGYAVQIYCDFSAYTDMAIGLALLLGFRFPDNFDRPYTARSLQDFWRRWHMTLSRWLRDYLYIPLGGNRGGSFKTYRNLMLTMLLGGLWHGAAWTFVIWGGIHGAGLAVERAWPSVANAMRFPTGIPARVPQPVKTAVARIVTFHVVCLAWVFFRAPDLNTAFAVLGRLFADGPGTGIVTPTVVLIIAAALAVQWLPRGTGARLRTAFVTLPVYAQGVSLGALLLVIAAVSGGQGVAPFIYFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E9</accession>
    <name>C7Q7E9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">DNA ligase</fullName>
            <ecNumber evidence="9 10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ligA</name>
        <name evidence="12" type="ordered locus">Caci_1313</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="9 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785531.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1313"/>
    <dbReference type="EnsemblBacteria" id="ACU70237">
        <property type="protein sequence ID" value="ACU70237"/>
        <property type="gene ID" value="Caci_1313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1313"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007764_2_1_11"/>
    <dbReference type="OMA" id="HDVEHEI"/>
    <dbReference type="OrthoDB" id="241401at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018239">
        <property type="entry name" value="DNA_ligase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="631"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU70237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="723" mass="78656" checksum="A2AF8804EE0C7731" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7F3</accession>
    <name>C7Q7F3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name evidence="2" type="ordered locus">Caci_1317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785535.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1317"/>
    <dbReference type="EnsemblBacteria" id="ACU70241">
        <property type="protein sequence ID" value="ACU70241"/>
        <property type="gene ID" value="Caci_1317"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1317"/>
    <dbReference type="eggNOG" id="COG0721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105899_1_0_11"/>
    <dbReference type="OMA" id="VTPMAMK"/>
    <dbReference type="OrthoDB" id="1780195at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="11182" checksum="2691355E90E5EAEE" modified="2009-10-13" version="1">MPAITREEVAHLALLSRLDLSDDELAHYAEQLDVILGSVARVSEAVQLLGQGQDIPPTSHALPLVNVTRPDVERPCLDPADVLGQAPAAQDQRFRVPRILGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K9</accession>
    <name>C7Q7K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787495.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3295"/>
    <dbReference type="EnsemblBacteria" id="ACU72202">
        <property type="protein sequence ID" value="ACU72202"/>
        <property type="gene ID" value="Caci_3295"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3295"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_20_2_11"/>
    <dbReference type="OMA" id="RAIMWSA"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="50849" checksum="45433FA0479624E3" modified="2009-10-13" version="1">MSVVSPPPVRVRADQQRLRGGALGLLDIAGSTMANIGPAMSFYFSFGFLATASGLASPLTIVAAGVAVALLGNTLAQFSRAHPSAGSFVTFVGTTFGGASAVATALLAALGYIIGISAVIAVSGGFLATTLEYYAGWSPAWVVWTLVLTAASAALIVRGIVLSTKVAGFFFAVELVMLLVVSVAAIVKHGGHLSAAPFLPSHIRGGMSGLAEGFPLAVYLFIGWENSAALAEESENPRRDVGRAVFSSIAVMSLSYVLFAYATVTGFGYDVHKVGAADVPFMVVARGTLGVLAFLAYIAGLTSTVGSLIAGANSQTRLLFNAGRERLLPAFLGYVHPTRRTPTNAILTFIAAALVIIGGWGLGHLVGHHGRMDATAFFAEASSMGSILILLVYLAANIALPFYYRRYRPTEFRAVRHVVLPLLGAVAIVVPLYYLVKPGQPAPYSWFPYVSLALLVASVAYALVLTRRDPTLGERVGAVVADGYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7M9</accession>
    <name>C7Q7M9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3315"/>
    <dbReference type="EnsemblBacteria" id="ACU72222">
        <property type="protein sequence ID" value="ACU72222"/>
        <property type="gene ID" value="Caci_3315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3315"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_0_1_11"/>
    <dbReference type="OMA" id="FARRECD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15144" checksum="361937982EC04BE4" modified="2009-10-13" version="1">MSLMPSSPPDNLDWLLNDFALRVPGVVHALAVSADGLVVAASADLTEEQAENLAAVASGLVGLLAGAARLLRAAPVQSNLTELFGGFLFSMAVSDGASLLVFARRECDIGQVSYTMAELINQVGAALTPMARSRMLARESAGRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7R7</accession>
    <name>C7Q7R7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787553.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3353"/>
    <dbReference type="EnsemblBacteria" id="ACU72260">
        <property type="protein sequence ID" value="ACU72260"/>
        <property type="gene ID" value="Caci_3353"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3353"/>
    <dbReference type="eggNOG" id="ENOG502ZVG4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045231_2_0_11"/>
    <dbReference type="OrthoDB" id="1593423at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021424">
        <property type="entry name" value="PorA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11271">
        <property type="entry name" value="PorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981454" evidence="3">
        <location>
            <begin position="26"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="385" mass="40276" checksum="1785D03F6AEFD760" modified="2009-10-13" version="1" precursor="true">MTKTRIACAVVGVLSLVAAALMAWWITPSYVARIPDGKNISRNYAGTFQSLLDPAALASGNLVGAVKQNVPMTVLQDVKAEQTSGDKALISDSRTTSAAGAKVEQTKWEYAVDRTSLQAVSSHPSSWNVIPAKGLTVSWPFGAKKKDYQGWTPETQTVAPLTYLRSEKKQGITTYVYEAKVAPTKIVDPQILAALPKQLPASLLKLLATAGGLPAAQAAQLEQILPQLGAQVTMAYTFQDDSTFWVDPNTGLVIDVLRKQQRIAAIALPNGTAVPLIPAVAAAYETTPASAHQAADDARHGHTVIRWLGVYLPIILLALGFVLLLLAALLRGRRRPAAPATGPGMSGPGTSGPGREGPAGPAGPAGPTDPEGPAGPVTDVTPPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B9</accession>
    <name>C7Q8B9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="13">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ordered locus">Caci_7278</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7278"/>
    <dbReference type="EnsemblBacteria" id="ACU76107">
        <property type="protein sequence ID" value="ACU76107"/>
        <property type="gene ID" value="Caci_7278"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7278"/>
    <dbReference type="eggNOG" id="COG1085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029960_1_1_11"/>
    <dbReference type="OMA" id="HAIYYPP"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 13" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="14">
        <location>
            <begin position="107"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="15">
        <location>
            <begin position="196"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="11 12">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU76107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="37836" checksum="68B71090C05446A2" modified="2009-10-13" version="1">MDLDLTRTVTKLSDGRELIYYDETPGQDRSAADERDLPTVSTTSELRRDALTGEITAVAGHRQDRTFLPAADQCPLDPSRPGHLSEIPAADYDVAVFENRFPSLAGSTGRCEVVVFSAEHAASFGALPVSRIRHIVDVWADRTSELASRPGVEYVYCFENRGVEVGVTLHHPHGQIYAFTFIPPRMQKMLDVAAAYHESTGGCVACDALVEEKAEGSRIITAGEYFTAYVPYAGRWPFQVDIVPNRHVPDIPALTSVERDELAVIGKDCVQRLDALFDGPMPYIGSWYQAPVTAGRAESHLRWQLAALRRAPGKLKYLAGTESGAGAFMNDIRPERAAAMLRGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z3</accession>
    <name>C7Q8Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate synthase (NADPH)</fullName>
            <ecNumber evidence="6">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3407</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787606.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3407"/>
    <dbReference type="EnsemblBacteria" id="ACU72313">
        <property type="protein sequence ID" value="ACU72313"/>
        <property type="gene ID" value="Caci_3407"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3407"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026563_1_0_11"/>
    <dbReference type="OMA" id="EDHVGMP"/>
    <dbReference type="OrthoDB" id="151647at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027283">
        <property type="entry name" value="YerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500060">
        <property type="entry name" value="UCP500060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982918" evidence="4">
        <location>
            <begin position="20"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="5">
        <location>
            <begin position="159"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="533" mass="58152" checksum="B97CBBFBB9E68402" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C2</accession>
    <name>C7Q9C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793997.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5409"/>
    <dbReference type="EnsemblBacteria" id="ACU74268">
        <property type="protein sequence ID" value="ACU74268"/>
        <property type="gene ID" value="Caci_5409"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5409"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_20_0_11"/>
    <dbReference type="OMA" id="CTHELPA"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="267" mass="28117" checksum="3303FFE66EE44402" modified="2009-10-13" version="1">MTPAPPAVPAPVPASTPAPVQAPAFTAVVIDFFGTLTTSAPDEVWFQAAAASAAPLGLEPALWRETLTASFVERATGALGDLPETFRALARRCGVDPSEGALAEACEARVKAQNELFVFREDVLGALQALKARGYRVGLLSDCTPELPVAWPQLAVSGFFDTAVFSCVEGLKKPNPAFFRLVAERLGVAPADCLYVGDGGSRELSGAAAVGMTPLMLRAEDWHSNSAYDREDDWAGAEIASFTALISKIDAAGLSARSLLAQHQDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9J3</accession>
    <name>C7Q9J3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794068.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5480"/>
    <dbReference type="EnsemblBacteria" id="ACU74339">
        <property type="protein sequence ID" value="ACU74339"/>
        <property type="gene ID" value="Caci_5480"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5480"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_1_11"/>
    <dbReference type="OMA" id="FLAEGPQ"/>
    <dbReference type="OrthoDB" id="1697536at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="35"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="28239" checksum="DE2BE73848D6FB25" modified="2009-10-13" version="1">MSEASPELSNPRAPRAVAARRLASRPFRAKQRLFLAEGPQAVREAADLDGVLVELFATGEAAERYGEILAAAGKQGSKITIATPELLASLSETVTPQGLIGVCRFLDVPLESFLAARAPKLVALLAHVRDPGNAGTVIRCADAAGADLVIVTSESVDVYNPKAVRASAGSLFHVPVAVGVSAQEAVDMLRAAELRVLAADGGGAADLDDELDAGRLAAPTCWMFGNEAWGLPEALLALADEAVRVPIHGRAESLNLATAAAVCLYSSARAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA24</accession>
    <name>C7QA24_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70422">
        <property type="protein sequence ID" value="ACU70422"/>
        <property type="gene ID" value="Caci_1501"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1501"/>
    <dbReference type="HOGENOM" id="CLU_362778_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="770" mass="77450" checksum="E892E38924BC8EAC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA42</accession>
    <name>C7QA42_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ordered locus">Caci_1519</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785734.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1519"/>
    <dbReference type="EnsemblBacteria" id="ACU70440">
        <property type="protein sequence ID" value="ACU70440"/>
        <property type="gene ID" value="Caci_1519"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1519"/>
    <dbReference type="eggNOG" id="COG0164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036532_1_0_11"/>
    <dbReference type="OMA" id="YPTKLHL"/>
    <dbReference type="OrthoDB" id="1685277at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="37"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU70440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23801" checksum="2FCF6D32E508899A" modified="2009-10-13" version="1">MTTTPTLTLPRGVAIRSDAGIYGYERALARAGFAQVAGTDEAGRGACAGPLVAAAVILRPGASGRIPGLSDSKLLTERARDRVRVEIEKRALSYAWVAIPAPEVDSRGLHQANIEALRRSVARLDVAPDYVLSDGFRVDGLPCPSLAMWKGDQVAACVAAASVLAKTVRDAMMTELAQRHPAYGFEIHKGYSTPAHQAALTEHGPCPEHRFTYANVANVSPRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB2</accession>
    <name>C7QAB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792140.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3505"/>
    <dbReference type="EnsemblBacteria" id="ACU72411">
        <property type="protein sequence ID" value="ACU72411"/>
        <property type="gene ID" value="Caci_3505"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3505"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2477670_0_0_11"/>
    <dbReference type="OMA" id="MDKADID"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="87" mass="9383" checksum="7AF88915300E9CB0" modified="2009-10-13" version="1">MIGPTEDIDHLAVVCAALAAEADPDLEGIDPDWQLTAIPGLESVKALRAVVRIEDACAIAIPDDFLFETNTVRQLADLVARLVEKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAI9</accession>
    <name>C7QAI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipopolysaccharide biosynthesis protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3583"/>
    <dbReference type="EnsemblBacteria" id="ACU72488">
        <property type="protein sequence ID" value="ACU72488"/>
        <property type="gene ID" value="Caci_3583"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3583"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038570_0_0_11"/>
    <dbReference type="OMA" id="GHYQPRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11579">
        <property type="entry name" value="Glyco_tran_WbsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032719">
        <property type="entry name" value="WbsX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41244">
        <property type="entry name" value="PTHR41244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14307">
        <property type="entry name" value="Glyco_tran_WbsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="357" mass="40980" checksum="CA9EE83E8C09A14F" modified="2009-10-13" version="1">MLDEAPLEVVAFFLPQFHPIPQNDSWWGTGFTEWTHTALARPLFEGHLQPRLPADLGFYDLRVPETRRAQWELAAHHGVTAFCYWHYWFGGGTRLLERPEQDLLKDPDLPHRYCLGWANQSWTGVWHGRGDEVLQQQRYPGEADDVEHFKCLLPHFTDERYLTVDGRPVFYLFRPDDIPDLARLVTLWRQLAADAGLPGLYLVGDADGAWVHDVDQHLDAAVWNPAPPPLGHSLADSFAGMPLREEPRAFQYDKIYADWLLNGSAAPIRRHPCVVPGFDNTPRSGRRGVLLHHPDPEIFEAAVTEAVRREQAMPDPRMLFIKSWNEWAEGSVMEPDQHFGRSFLRALRRGLDVRPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAJ7</accession>
    <name>C7QAJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Esterase, PHB depolymerase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792225.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3591"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72496">
        <property type="protein sequence ID" value="ACU72496"/>
        <property type="gene ID" value="Caci_3591"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3591"/>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_1_0_11"/>
    <dbReference type="OMA" id="GWNSECA"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983072" evidence="2">
        <location>
            <begin position="35"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="410"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="53190" checksum="BFC541C29DF6109D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAT4</accession>
    <name>C7QAT4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794136.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5548"/>
    <dbReference type="EnsemblBacteria" id="ACU74407">
        <property type="protein sequence ID" value="ACU74407"/>
        <property type="gene ID" value="Caci_5548"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5548"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_4_11"/>
    <dbReference type="OMA" id="HDMHLHA"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="20974" checksum="5F1266456AD653B8" modified="2009-10-13" version="1">METLDRVVEPTEIVAGRYQLRPPSLRDVPDMMEMSRDADIALWNPLASGVDEEAARAWAERFADWDGGRSALFGVYEAVEGRLLGLVSLHRIDLHLSFGELGYRVAPWARGRGVATMAVGTVAEWAFGYLELTRLQLLHGVENVASCRVAEKCGFLHEGTTRSSYRYGDGELHDEHIHGRLIGDPAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ9</accession>
    <name>C7QAZ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="11" type="ordered locus">Caci_5613</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794201.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5613"/>
    <dbReference type="EnsemblBacteria" id="ACU74472">
        <property type="protein sequence ID" value="ACU74472"/>
        <property type="gene ID" value="Caci_5613"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5613"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_1_1_11"/>
    <dbReference type="OMA" id="HIECFDN"/>
    <dbReference type="OrthoDB" id="1036075at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="9">
        <location>
            <begin position="16"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="208"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="10">
        <location>
            <begin position="259"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="211"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="663" mass="73646" checksum="A00C377ADDCB83A7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB64</accession>
    <name>C7QB64_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796080.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7530"/>
    <dbReference type="EnsemblBacteria" id="ACU76355">
        <property type="protein sequence ID" value="ACU76355"/>
        <property type="gene ID" value="Caci_7530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7530"/>
    <dbReference type="eggNOG" id="ENOG503362Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529533_0_0_11"/>
    <dbReference type="OrthoDB" id="2012417at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21469" checksum="C843E02125E6C3AC" modified="2009-10-13" version="1">MSDVERTDLNRLRDIIRSAQQQGDQYPVDPKARITVGSEGEIYTGVVPTGRPLSKVQHGTFAARVRGREVEDLQWAAKHMPRNTQFIEHRDARGWCYSFLSQMGRPYTMFAYFDGTSYQVKLVEPRLEGLVGAHAGHLYANGRLCLSQAGGSGQPTLEEAYSKSVLWATGMDVVLAGYPFPFSTNNEFEYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB74</accession>
    <name>C7QB74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796090.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7540"/>
    <dbReference type="EnsemblBacteria" id="ACU76365">
        <property type="protein sequence ID" value="ACU76365"/>
        <property type="gene ID" value="Caci_7540"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7540"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_5_11"/>
    <dbReference type="OMA" id="EIVTPIW"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="17803" checksum="87DEE7771F77F614" modified="2009-10-13" version="1">MSTTAAEIAEAWRRERPGTPVDAIEVFTPIVRLAKLLTDDRTRVLRAAGIDTATLDLLSVLRRSGPPYTLTTRELTERTLVTAGAISQRVARAEQEGLVTRAPDRSGHKAVAVSLTAAGHAVIERSVDAVLGRDSELVAGLTVEEREVVIPLLDKLEGFVRARTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB88</accession>
    <name>C7QB88_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796104.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7554"/>
    <dbReference type="EnsemblBacteria" id="ACU76379">
        <property type="protein sequence ID" value="ACU76379"/>
        <property type="gene ID" value="Caci_7554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7554"/>
    <dbReference type="HOGENOM" id="CLU_1685611_0_0_11"/>
    <dbReference type="OMA" id="EFFHLDW"/>
    <dbReference type="OrthoDB" id="1468357at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="163" mass="17571" checksum="3432256E45AA7512" modified="2009-10-13" version="1">MPTTMLVVEQTINQHDLEYVVGLHADNVADGMDPESYVVVVPVGKENGKVLATLDDLALGNFKGAEEDSHGEPLNEAVVAARAVMTATVEAFQKAGRQASGELLAGPPVEGLKEIAAKYLAEEIIVLTVPHLVEEFFHRDLASRLRKATDLPTLRLLAHVPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBK9</accession>
    <name>C7QBK9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenosine kinase</fullName>
            <ecNumber evidence="2">2.7.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.20" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785880.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1665"/>
    <dbReference type="EnsemblBacteria" id="ACU70586">
        <property type="protein sequence ID" value="ACU70586"/>
        <property type="gene ID" value="Caci_1665"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1665"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_5_2_11"/>
    <dbReference type="OMA" id="SQQIARM"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="32"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="35694" checksum="191F7DBCD6CB2B36" modified="2009-10-13" version="1">MRVAVAGSIATDHLMSFPGRFAEQLVADQLHTVSLSFLVDSLEIRRGGVAPNICFGMGRLGLRPVLVGSAGEDFGEYRSWLERNNVDCESVRISDLLHTARFVCTTDADHNQIASFYTGAMAEARLIEIGPVADRVGGLDLLLIGADDPEAMLRHTQECRERGIPFAADPSQQLARMPAEDIKQLVDGAKYLFTNEYEAALIEQKTGWDAEEILRRVGARVVTLGANGVRITRRTEDGEIQVLEVATPKEEAKADPTGVGDAFRAGFIAGLSWGAGEELAAQVGCMLATLVIETIGTQEYDLSRGRFLERFALAYGTDAADQVVRHLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD47</accession>
    <name>C7QD47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786051.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1836"/>
    <dbReference type="EnsemblBacteria" id="ACU70757">
        <property type="protein sequence ID" value="ACU70757"/>
        <property type="gene ID" value="Caci_1836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1836"/>
    <dbReference type="eggNOG" id="COG2017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052486_1_1_11"/>
    <dbReference type="OMA" id="NIDLIRP"/>
    <dbReference type="OrthoDB" id="710313at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09022">
        <property type="entry name" value="Aldose_epim_Ec_YihR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037480">
        <property type="entry name" value="YihR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="34068" checksum="4DEB227CAC2B2489" modified="2009-10-13" version="1">MISIPHTGSGGERPTGQQYTIKAGEYAATVTEVGAALRALRLNDRELIMEFPEDGVPVGGSGQLLIPWPNRIRDGKYTFRGVERELEISEAARHNAIHGLTRLAHWTPETHTDSSLRMTVRLEPQPGYPFALDVAAEYTLDADEGLTVSVTARNAGEWEAPYGIGSHAYLKTDGGLDGPQGLAQVPAGRWLMVDERMIPQCEVPVAGTPYDLRDRRPLRGLTLDTAYTDIVRDNDGRARVTLGQGADGVTMWFGEGLEWVQLFSGDPLDPPYHRSALAVEPMSCPPDAFNSGKGLIALEPGASVTHTWGIVSGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD74</accession>
    <name>C7QD74_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792396.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3765"/>
    <dbReference type="EnsemblBacteria" id="ACU72667">
        <property type="protein sequence ID" value="ACU72667"/>
        <property type="gene ID" value="Caci_3765"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3765"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_1_11"/>
    <dbReference type="OMA" id="RWNLASE"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980854" evidence="2">
        <location>
            <begin position="38"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="80"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="35076" checksum="E42AF3F4C7C31340" modified="2009-10-13" version="1" precursor="true">MSVKPLRLLAPALAAALGLALSACASSASNHPATAPAAAGSGVVHVGSLSNGAATPVELSVAQQDQIRAELPASIRDGGQLRVAIGDLPAGTPPLFFVGSDQKTLTGSEPDLARLVAGVLGLKPAFDNANWDNMFVAIDSGKDAVGFANITDTEKRKEKYDFASYREDNLGFEVLKSNPWTFGGDYRALAGKTIAVGSGTNQEKILLEWQTKLRAEGKDFSVKYYPDANSTLLALTSGKIDIFLGANPGVAYQVTQTAKSPTPTRIAGEYSGAGGSLQGLIAATTKKDSGLAKPIADAINYLIQNGDYAKWLAAWNLGDEAVQTSQVNPPGLPITNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEL9</accession>
    <name>C7QEL9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72789">
        <property type="protein sequence ID" value="ACU72789"/>
        <property type="gene ID" value="Caci_3901"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3901"/>
    <dbReference type="HOGENOM" id="CLU_2631690_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="8545" checksum="97B73F75EF2F0097" modified="2009-10-13" version="1">MLRMVRCQQAIALYRWLAAIRSSWVEPDLALFPGYPKRSWHETMPAPTRLTAGPVLASGRHLAMLARFVGTPAGVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEP1</accession>
    <name>C7QEP1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD40 domain protein beta Propeller</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3925"/>
    <dbReference type="EnsemblBacteria" id="ACU72811">
        <property type="protein sequence ID" value="ACU72811"/>
        <property type="gene ID" value="Caci_3925"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3925"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011452_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="647" mass="69582" checksum="1EB16CFD05199B6A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEQ5</accession>
    <name>C7QEQ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3942"/>
    <dbReference type="EnsemblBacteria" id="ACU72825">
        <property type="protein sequence ID" value="ACU72825"/>
        <property type="gene ID" value="Caci_3942"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3942"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_1_11"/>
    <dbReference type="OMA" id="RMSEFAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="83"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="755" mass="80705" checksum="C9D1A0AB5283F3DB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEQ6</accession>
    <name>C7QEQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3943"/>
    <dbReference type="EnsemblBacteria" id="ACU72826">
        <property type="protein sequence ID" value="ACU72826"/>
        <property type="gene ID" value="Caci_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3943"/>
    <dbReference type="HOGENOM" id="CLU_2128987_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="11880" checksum="FCAA629F452167CD" modified="2009-10-13" version="1">MDSILTPAMVSAALTKLLDSAATQAGSKAWDALKAIVSRHRGQAPEQPTNPEEAAALADELTAAAEKDPALARDLSAWHQSIVGSDNTMNNVSGSAERVVQGRDFPHANITFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF57</accession>
    <name>C7QF57_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794544.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74815">
        <property type="protein sequence ID" value="ACU74815"/>
        <property type="gene ID" value="Caci_5957"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5957"/>
    <dbReference type="HOGENOM" id="CLU_1486520_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983095" evidence="2">
        <location>
            <begin position="34"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="16847" checksum="51796A81B6350194" modified="2009-10-13" version="1" precursor="true">MSTTRGVRILVGTALASSIILLGGCASSGTTPAAGGSTSNPLGGSTSHSTAASTGGSSSSSSSDDSSSSSSSSSDDSSSSGGLTGNSNDPGCSAAESDVTSGTTAMSNAGSDPAGALAAIKAIGDKLHADAGKSTNPTAAAAIKKVGDDYVNVATQAAAGKAPDTTSMVNDATAMATACEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF97</accession>
    <name>C7QF97_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7850"/>
    <dbReference type="EnsemblBacteria" id="ACU76674">
        <property type="protein sequence ID" value="ACU76674"/>
        <property type="gene ID" value="Caci_7850"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7850"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_20_2_11"/>
    <dbReference type="OMA" id="SNRRCKT"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="143" mass="15694" checksum="73AE0B872F497FB3" modified="2009-10-13" version="1">MSDYPSKDAYRAHAAMQKLVLHQRDMRGAVEKATGVSFGRGRALRRLVDGPLRMSELAARLGWDKPYTTTVVDDLEERGLVTRNVAPDDRRAKMVELTPDGHAVAVTAIQILAEPAPGLARLNAEELAVVADLLEKASVENEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFA2</accession>
    <name>C7QFA2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796404.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7856"/>
    <dbReference type="EnsemblBacteria" id="ACU76679">
        <property type="protein sequence ID" value="ACU76679"/>
        <property type="gene ID" value="Caci_7856"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7856"/>
    <dbReference type="eggNOG" id="ENOG503426S">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2191333_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="11408" checksum="F7EE9557D6967B5A" modified="2009-10-13" version="1">MAGAKKESKTARASVRAGAGGAGGGRVFGDMKRFTPLGGGFCYFANSDGKSLHLKVDSEELFTVLSAIEGADRAKVDAEVTELAAKYGEKVPAWKALAEKLTAGELAEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFC7</accession>
    <name>C7QFC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7881"/>
    <dbReference type="EnsemblBacteria" id="ACU76704">
        <property type="protein sequence ID" value="ACU76704"/>
        <property type="gene ID" value="Caci_7881"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7881"/>
    <dbReference type="HOGENOM" id="CLU_3041638_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="5611" checksum="B58D7317DC7D52BE" modified="2009-10-13" version="1">MVDPLRQLTDATICLAALDPLLYDTGGSLAVARAAEQVSRAAEGVLVRLCPDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFP6</accession>
    <name>C7QFP6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784280.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0030"/>
    <dbReference type="EnsemblBacteria" id="ACU68985">
        <property type="protein sequence ID" value="ACU68985"/>
        <property type="gene ID" value="Caci_0030"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0030"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="CADRYED"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="109"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU68985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="181" mass="20142" checksum="10FFB6773E5155C4" modified="2009-10-13" version="1">MRPEDEDEFRRFTAARWPGLVRTAYLLTGDLGHAEDLAQTTLIKAYRSWHRVCRVEDVDAYVRKILINANRSRFRSKRPLEYSVAAVPEYPAWPPDDGSGVEERTVLFAALATLPPRQRAIVVLRYWEDLAEGEVAALVGCSVGTVKSQASRALAKLRKDARLAGLSAFQEPAAAMKGAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG65</accession>
    <name>C7QG65_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792639.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4042"/>
    <dbReference type="EnsemblBacteria" id="ACU72910">
        <property type="protein sequence ID" value="ACU72910"/>
        <property type="gene ID" value="Caci_4042"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4042"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071835_0_0_11"/>
    <dbReference type="OMA" id="YKVSELC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="25"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="37547" checksum="801D92C0FC02121D" modified="2009-10-13" version="1">MPKKMTTAPAPATTDTPLTADAPALTPAASTVLSLLDAHDGTTTVDLVERTGLGRSTVTKALVALHEAGLAVRQEGGHEGTRRIADRWFAAPGATADTAAPADAEGQADDDSVADPAETMDGDAEADDADAIPAPPHDAAEEDATTTTPSQSLAADIDAARTEPLSDQQPDGADADAETETESGAEPVEAEPDLDPADAEAQDDELSEAEPTTPDDIEPETGPDTDETAAEPADGPTEHAETGGDSPNASEASQKSDSPSDAADQDTDVIRDTDTDDAAPAPEAAEDAPSAPRLGKGELRAQVEEHLREHPDRAWTPTAISKVLNRSAGAINNACVKLSESGVVTAFTDKPIRFQWKDQQGADAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG99</accession>
    <name>C7QG99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4079"/>
    <dbReference type="EnsemblBacteria" id="ACU72944">
        <property type="protein sequence ID" value="ACU72944"/>
        <property type="gene ID" value="Caci_4079"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4079"/>
    <dbReference type="eggNOG" id="COG0433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013918_1_0_11"/>
    <dbReference type="OMA" id="AIGWAHA"/>
    <dbReference type="OrthoDB" id="859985at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019476">
        <property type="entry name" value="T4SS_TraD_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032689">
        <property type="entry name" value="TraG-D_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12696">
        <property type="entry name" value="TraG-D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10412">
        <property type="entry name" value="TrwB_AAD_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrwB_AAD_bind" evidence="2">
        <location>
            <begin position="432"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="TraG-D_C" evidence="3">
        <location>
            <begin position="692"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="876" mass="93135" checksum="F262C5344B5A55E3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGE9</accession>
    <name>C7QGE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4130"/>
    <dbReference type="EnsemblBacteria" id="ACU72994">
        <property type="protein sequence ID" value="ACU72994"/>
        <property type="gene ID" value="Caci_4130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4130"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057862_1_0_11"/>
    <dbReference type="OMA" id="GLYADWE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="292" mass="32254" checksum="BE01E8BACA15A44B" modified="2009-10-13" version="1">MATVILGDMDDLAGFLRTRRSRVDPAVAGIPTDSRRRVEGLRREEVAHLSGVSVDYYVRLEQGRATQPSDQVLDALAGVLGLDETERGHLYRLARKPRRRAKTPSTRIRPELLRVLDLVADAPALIMDHRLDVLAGNRLAGLLYGRPIPGLNVARHIFLEEAERGFYAEWETCTLDVVGHLRLAVGRYPDDPRLASLVGELAMGSERFRRLWARADVRARTHGCKVYHHPLVGLLELHQENFALPGESNMELLVMTAAPGSPTEDGLRLLAGLGADSGAGHQTVPTENAHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGF1</accession>
    <name>C7QGF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4132"/>
    <dbReference type="EnsemblBacteria" id="ACU72996">
        <property type="protein sequence ID" value="ACU72996"/>
        <property type="gene ID" value="Caci_4132"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4132"/>
    <dbReference type="HOGENOM" id="CLU_3341851_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="37" mass="3649" checksum="97D9BEE577F13731" modified="2009-10-13" version="1">MAAVGSGREIGECALHSPAPYDAVQAVLTAYAASLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGQ9</accession>
    <name>C7QGQ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794668.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6083"/>
    <dbReference type="EnsemblBacteria" id="ACU74939">
        <property type="protein sequence ID" value="ACU74939"/>
        <property type="gene ID" value="Caci_6083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6083"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_11"/>
    <dbReference type="OMA" id="WQAVEAN"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="45"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="35491" checksum="84C5CC5595AC9409" modified="2009-10-13" version="1">MTDPNSERPAPFGKRYEVHGRSLQTYRTGAADGDGDLSAGAGATVVLLPGGGSVGLDMWRVQEGVAQFATVVSYDRGGTGWSSRDVTLPRTLAEVTGELRNLLELLRAEGVSGPYIIVGHSLGGLYARYFATQHPEQVAALVLIEPGHEDLRKYMPKELTDLWDGFDPDAVLPDEIHEVPQEIRDFYRGLFQDAMAQFPAEIREPLVANHVHRAWLRGGIQESSNVKALGEEMRAVADAVPDVPTVLLTAMDIDPFKRAVIAGMSEELVAAETAGKLRLYDEVAASFTHGENRRVEGVGHVTLVMQRPDAVVDAVRDLMGLSRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS1</accession>
    <name>C7QGS1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6096"/>
    <dbReference type="EnsemblBacteria" id="ACU74951">
        <property type="protein sequence ID" value="ACU74951"/>
        <property type="gene ID" value="Caci_6096"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6096"/>
    <dbReference type="eggNOG" id="COG3688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044346_0_0_11"/>
    <dbReference type="OMA" id="KFAGNAM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34547">
        <property type="entry name" value="PTHR34547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="441" mass="46662" checksum="9B6EE29DB90E61E3" modified="2009-10-13" version="1">MSSPEGERLTITLPDSVRQRVVEIASEALGKMPAAEIPAPLRPFAKFTPAKRAKAAAIPMAASLESDGAFRTRVAERVREASPDLSDSLFAGVVPAAADPHEVAAVAYVLRPHGWTGIVKDALEAVTQGARLAAGEAAESEVARLAAEVAELRETARVAADSLRVAQEEARREGDQLRRKVRQLEADMRRAQAAARAAETALETERTSAASAASASEAELRRLRTRLTAAETALDTARRSARSGRSEGDMRLRLLLDTVTGAVKGLERELALPPTETRPADTVGAASPDSVAPSDMSVQGRAKDDPALLDQYLALPMVHLVVDGYNVTKSGYPTLPLAEQRVRLVGGLAALAARTGAEVTCVFDGAALDGPVRLTQPRGVRVLFSAPGEIADELIRRLVAAEPAGRPVVVVSSDREVAEGVRRSGARPVPASMLLNRMARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV3</accession>
    <name>C7QGV3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">purH</name>
        <name evidence="10" type="ordered locus">Caci_7980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7980"/>
    <dbReference type="EnsemblBacteria" id="ACU76803">
        <property type="protein sequence ID" value="ACU76803"/>
        <property type="gene ID" value="Caci_7980"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7980"/>
    <dbReference type="eggNOG" id="COG0138">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016316_5_2_11"/>
    <dbReference type="OMA" id="WRVAKFV"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="528" mass="55810" checksum="4C2407636CB05219" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGW2</accession>
    <name>C7QGW2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA containing CoxE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796537.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7989"/>
    <dbReference type="EnsemblBacteria" id="ACU76812">
        <property type="protein sequence ID" value="ACU76812"/>
        <property type="gene ID" value="Caci_7989"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7989"/>
    <dbReference type="eggNOG" id="COG2425">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058765_0_0_11"/>
    <dbReference type="OMA" id="DIDWNRT"/>
    <dbReference type="OrthoDB" id="434825at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="43681" checksum="6DE88ABF9E373252" modified="2009-10-13" version="1">MPDTLETADDERMRRWRLVLGGDDDGTGAKLTGLDLEMDKALAVLYNKGGYETGAGAVTTRSRGRGGQQAQRSAGLGASSPQVARWLGDIRGYFPQTVVQIMQRDAIDRLNLRQLLLEPEMMESVEPDVHLVGTLLSLNHLMPAETKETARQVVRKLVEDLERRLGAKLRATVSGALDKSTRTSRPRHSDIDWGRTIQANLKNYLPEYRTIVPERLVGYARKERAVKRDVVLAIDQSGSMYASVVYASVFGAVLASLKSLKTSLVVFDTAVVDLTPQLTDPVDVLFGTQLGGGTDINRAIAYSQSLISRPTESIFILISDLYEGGVRREMLRRVAEMTAAGTQVIVLLALSDEGAPSYDRENASALAALGVPAFACTPDKFGDLMAAAIQRQDLGKFLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH13</accession>
    <name>C7QH13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8040"/>
    <dbReference type="EnsemblBacteria" id="ACU76863">
        <property type="protein sequence ID" value="ACU76863"/>
        <property type="gene ID" value="Caci_8040"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8040"/>
    <dbReference type="HOGENOM" id="CLU_111512_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021903">
        <property type="entry name" value="DUF3515"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12028">
        <property type="entry name" value="DUF3515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="17779" checksum="7B1850416A141118" modified="2009-10-13" version="1">MWGYHAGRTGAVRVDLPKTSDQAVLTACANLIKALPSEVEGEHRRGAVGDDVHVAQRAAAWGPTATVLRCGVAEPAAIVVGGPDYTPLSNQYAGMGPDESAQVNWLIEDHGDHATFTTTDRALYVQVTVPYDTATEKQNASNVLVDIAPAIVKTVPTKAGQFVSDQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHA9</accession>
    <name>C7QHA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784343.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0093"/>
    <dbReference type="EnsemblBacteria" id="ACU69048">
        <property type="protein sequence ID" value="ACU69048"/>
        <property type="gene ID" value="Caci_0093"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0093"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_0_11"/>
    <dbReference type="OMA" id="GMFRGVN"/>
    <dbReference type="OrthoDB" id="1248201at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="4">
        <location>
            <begin position="55"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="375" mass="41618" checksum="C35EC191633DD1E5" modified="2009-10-13" version="1">MVTSRKGAGGKTAAKKKAGPADPDLVQLLTPDGDLVEHPEYSIDLTPEEYRGLYRDMVLVRRIDAEGTALQRQGELGLWAPLLGQEAAQVGSGRAQTAEDYAFPTYREHGVAWCRDVDPVNLLGMFRGVNNGGWDPNEKNFHLYTIVIGSQTLHATGYAMGMQRDGREAAVIAYFGDGASSQGDVNEAFVFASVNNAPVVFFCQNNQWAISEPNERQFRVPLYQRAAGFGFPGVRVDGNDVLACLAVTRAALERARTGNGPMLVEAFTYRMGAHTTSDDPTRYRSSDELEEWKAKDPILRMRAFLEKSKYADEAFFKEVDTEADTVAADIRERCVTMPDPKPISIFDHVYAEPHPLMDEERAEYGAYWESFEGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHC4</accession>
    <name>C7QHC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0108"/>
    <dbReference type="EnsemblBacteria" id="ACU69063">
        <property type="protein sequence ID" value="ACU69063"/>
        <property type="gene ID" value="Caci_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0108"/>
    <dbReference type="eggNOG" id="COG2331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136025_1_0_11"/>
    <dbReference type="OMA" id="EYACHAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="13371" checksum="63C01C727501C581" modified="2009-10-13" version="1">MPTYQYQCKDCGEALEVVQKFTDDALTVCPNCQGDLRKVFSAVGIVFKGSGFYRTDSRSSSSSSTPPGSSSNGSSGSGSGSSSDSGSGSGSGSSGSGSSSGSGGSSGSGSSGGSSKGGSSSSSSSTSSSSSSSSGSSSSTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHF1</accession>
    <name>C7QHF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784385.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0135"/>
    <dbReference type="EnsemblBacteria" id="ACU69090">
        <property type="protein sequence ID" value="ACU69090"/>
        <property type="gene ID" value="Caci_0135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0135"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_0_11"/>
    <dbReference type="OMA" id="WANVNEG"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="988"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1052" mass="110675" checksum="570D4822566E21DD" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHI9</accession>
    <name>C7QHI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784423.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0173"/>
    <dbReference type="EnsemblBacteria" id="ACU69128">
        <property type="protein sequence ID" value="ACU69128"/>
        <property type="gene ID" value="Caci_0173"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0173"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_4_1_11"/>
    <dbReference type="OMA" id="LYFPMLI"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="24"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="27099" checksum="208488258DE51059" modified="2009-10-13" version="1">MSTATFSSRSSRLLPEFRMTGNGFRTLVRTQARLLWREPAVVLSGIALPVLLIIVFGCIPSFGKPAASLGGRTTMDVYVPTFAMLSSVLTALTALPVTFADLRERGVLRRLAVSPVPAAGLLAAQVTVIATTAAVTAASVVLIGVAGFGASLPAHLALVLASYILGTTALLAIGLLIAALAPSAGVATGFGVPTMILNFFFAGVYVPLQQLPSVLRTASGFVPYGAIVDTWSGTGAAWQHLTVLAVYTVVGALAAARVFKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHL7</accession>
    <name>C7QHL7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2123"/>
    <dbReference type="EnsemblBacteria" id="ACU71042">
        <property type="protein sequence ID" value="ACU71042"/>
        <property type="gene ID" value="Caci_2123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2123"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_11"/>
    <dbReference type="OMA" id="VYVSHDQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="32"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="542" mass="53645" checksum="0D4317F5892620CA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI54</accession>
    <name>C7QI54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4235"/>
    <dbReference type="EnsemblBacteria" id="ACU73099">
        <property type="protein sequence ID" value="ACU73099"/>
        <property type="gene ID" value="Caci_4235"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4235"/>
    <dbReference type="HOGENOM" id="CLU_1966588_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="127" mass="13464" checksum="6FB3C3E03A28A439" modified="2009-10-13" version="1">MDWILLTELSSMFAGPWHAAELSAVPNVVADADASTDAGADASADTGSALTAADVWIAQQAYAFIAKRTVCERCGARLSRKVCVAVSPDGAKRIGVAARCRGWRRHPYTALVGRSRDGLRFGTLEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG2</accession>
    <name>C7QIG2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylacetic acid degradation protein paaN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6185"/>
    <dbReference type="EnsemblBacteria" id="ACU75039">
        <property type="protein sequence ID" value="ACU75039"/>
        <property type="gene ID" value="Caci_6185"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6185"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036377_1_0_11"/>
    <dbReference type="OMA" id="CNTFPTW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011975">
        <property type="entry name" value="PaaN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02288">
        <property type="entry name" value="PaaN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="90"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="555" mass="59299" checksum="C1280F32BF1402C0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIP8</accession>
    <name>C7QIP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796673.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8125"/>
    <dbReference type="EnsemblBacteria" id="ACU76948">
        <property type="protein sequence ID" value="ACU76948"/>
        <property type="gene ID" value="Caci_8125"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8125"/>
    <dbReference type="eggNOG" id="COG0498">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028142_4_1_11"/>
    <dbReference type="OMA" id="DDVNRFC"/>
    <dbReference type="OrthoDB" id="428821at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="83"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="416" mass="43842" checksum="E40C67088898E41E" modified="2009-10-13" version="1">MSGTLSTAAPFGSAAHLSCRECGHTTDLGPTFACEECFGPLEISYDFGTVTREQIEAGPASIWRYAPLLPVPADVATRPTTNPGWTRLVRATNLGRELGLTNLHVKDDSGNPTHSFKDRVVAIAVQAAHAFGYTTLSCSSTGNLAGAVGAAAARAGLDSCVFIPSDLEKEKIVVASVYGGRLIAIDGTYDEVNRFCSELIGDELGEKWGFVNVNLRPYYAEGSKTLAYEIAEQLGWRLPEQIVVPVASGSQLTKIDKGFRELVKLGLVEDTPYKVIGAQGSGCAPVSQAYKDGIDVIRPVRQPDTIAKSLAIGNPADGPYVLDIARRSGGTVEDVTDDEIRAAVKQLARTEGIFAETAGGVTVGVLKKLADAGRLDPEALTVVINSGDGLKTLDAVSDCGPTATIKPSLDAFRATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS3</accession>
    <name>C7QIS3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8150"/>
    <dbReference type="EnsemblBacteria" id="ACU76973">
        <property type="protein sequence ID" value="ACU76973"/>
        <property type="gene ID" value="Caci_8150"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8150"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_47_0_11"/>
    <dbReference type="OMA" id="PLYRWSR"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="12"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="412" mass="42308" checksum="86C0097EE230EA24" modified="2009-10-13" version="1" precursor="true">MVTRQNRAPAKLLLILGALSMFGPLSLDMYLPALPDLAHSFRTPEANVQLTLTACMIGLAVGQLVAGPMSDAWGRKKPLAIGLIAYAATSLFCAVAPDVYSLTAARLLQGLAGAAGLVISRAMVRDLYEGDALTKFFSTLMLVNGLAPILAPVIGGQLTRFMSWRGVFIVLAAIGVALLAATVLGLKETLPAASRGTSGGGLPATLRTFRVLMRDRGFMGYILTGGFAFAAMFAYISGSPFVLENIHGLSKQQFSLVFGTNALGIMIAGQAGGRLVGRVAPARLLGAGLVMSFGGSTILLIATAGFGGSLPGTLLGLFLMVSSIGVIMPQVTALALSGYEPAVAGAASAMIGTGQFLFGAIFAPLTGLGSKTSGMPMAMVIFGLSAAAVVMRALLVRTPRIESEPIVEPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIW5</accession>
    <name>C7QIW5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8192"/>
    <dbReference type="EnsemblBacteria" id="ACU77015">
        <property type="protein sequence ID" value="ACU77015"/>
        <property type="gene ID" value="Caci_8192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8192"/>
    <dbReference type="eggNOG" id="COG1091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045518_1_2_11"/>
    <dbReference type="OMA" id="AGETTWH"/>
    <dbReference type="OrthoDB" id="1076083at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="17"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="301" mass="31204" checksum="EDB5DF72537A8271" modified="2009-10-13" version="1">MTRPIVIVPGREAPRRWLVTGAGGMLGTDLVALLKAEPAAQVTALTRAELDVTDASAVAAAVAGHDIVVNAAAWTDVDGAETHEAQATAVNGGGVSSLASACAATGARLLTVSTDYVFDGKGEAPYGEYAATDPINAYGRSKLVGERAVLAVLPETGYVVRTAWLYGAHGPNFVRTMLRLAGERETLDVVDDQIGQPTWTGALAGQLIALAQASQAPAGIYHGTASGQTSWFGLARAAFEEAGLDPERVRPTTSDKFVRPAERPKYSVLGHDRWAEAGLPELGDWRGMLAASGVATAGQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ98</accession>
    <name>C7QJ98_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0287</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0287"/>
    <dbReference type="EnsemblBacteria" id="ACU69240">
        <property type="protein sequence ID" value="ACU69240"/>
        <property type="gene ID" value="Caci_0287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0287"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="WFAEYQP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="27"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="284" mass="29970" checksum="A1C8104C27449D77" modified="2009-10-13" version="1">MSAMTVADSGLADTGADTRSHAWVHARIMLRRNLRHLQRYPSLTLMVTLMPLVFLLLFVYVFGGTLGSGLGSLTPAGVHGGRAAYAAYVAPAIIVMAVAAAAQGTAIAVAQDMTEGIIARFRTMAVARSSVLTGHVVGAAIQTMAGVAVVVGAALAVGFRPHANAAEWFAALGVVLLLTFAVTWLCVGLGLSAKSVETASNSPMFLLLLPFLSSGFVPTDSLPTGMRWFSEYEPFTPVTETLRGLLTGTRIGGDLVVTLAWCLGVAVLSYAWSRRLYEREPKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG5</accession>
    <name>C7QJG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2270"/>
    <dbReference type="EnsemblBacteria" id="ACU71188">
        <property type="protein sequence ID" value="ACU71188"/>
        <property type="gene ID" value="Caci_2270"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2270"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_9_3_11"/>
    <dbReference type="OMA" id="TGYEDGN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="13"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="19106" checksum="3FA7E8315CBF7F69" modified="2009-10-13" version="1">MSGIRKATNGRESCLLAVHLILQRPDDERVLLGLRKGAVWGSGRWHVPAGHVEPGEDAVQALVREAREELGVRIDPGDLEHAVTVHHREADGEPRMQLFFAASRWSGGPVNAEPGKCEKLGWFRVDDLPSATVGYTRTALSSWHAGRSFAVCWRDSKRVDRGLGSRLIAGLQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJL1</accession>
    <name>C7QJL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786527.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2316"/>
    <dbReference type="EnsemblBacteria" id="ACU71234">
        <property type="protein sequence ID" value="ACU71234"/>
        <property type="gene ID" value="Caci_2316"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2316"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_9_2_11"/>
    <dbReference type="OMA" id="SYACYTM"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="160"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="29925" checksum="66C2401137396994" modified="2009-10-13" version="1">MIYLVLSGVLWGTGGLTGRLLSLHTRLSPTAVAGYRLLIGGTLLILFAAVTGRGRRDAGPAARSRRPRGRAAWRRVGVVGALSAGFQACYFAAVALTDVSLATLVTIGAAPVLVAAFEQATGRRGFDPRAAATVALALAGLGLLVGEPPHGVTGAHLAAGAGFAVASAAGFSAISVLGKNPVAGLGEVTMTGYSFTLGGLALVAAAALTTGAGFAPRPAAVGLLLLLGLVPTAIAYGCYFIGLREAAASTGTVTALLEPLTGTVLAVLLLGDRLTAVGAVGAALLAVSVTAETWHARPRVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK09</accession>
    <name>C7QK09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tail sheath protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792976.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4383"/>
    <dbReference type="EnsemblBacteria" id="ACU73247">
        <property type="protein sequence ID" value="ACU73247"/>
        <property type="gene ID" value="Caci_4383"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4383"/>
    <dbReference type="eggNOG" id="COG3497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009303_1_0_11"/>
    <dbReference type="OMA" id="GPRPIEG"/>
    <dbReference type="OrthoDB" id="558210at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="261"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="427"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="544" mass="57597" checksum="C4C9CF4FD7D076DF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK3</accession>
    <name>C7QKK3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796827.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8279"/>
    <dbReference type="EnsemblBacteria" id="ACU77102">
        <property type="protein sequence ID" value="ACU77102"/>
        <property type="gene ID" value="Caci_8279"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8279"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_2_4_11"/>
    <dbReference type="OMA" id="GRWKVFP"/>
    <dbReference type="OrthoDB" id="1558246at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="222"/>
        </location>
    </feature>
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        <location>
            <begin position="234"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="19"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="680" mass="72522" checksum="E2642E12C76FE984" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVG5</accession>
    <name>C7PVG5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ordered locus">Caci_0368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
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        <property type="protein sequence ID" value="ACU69321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0368"/>
    <dbReference type="EnsemblBacteria" id="ACU69321">
        <property type="protein sequence ID" value="ACU69321"/>
        <property type="gene ID" value="Caci_0368"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0368"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_4_0_11"/>
    <dbReference type="OMA" id="LFGCPGW"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="106"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="238"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="34450" checksum="69E7202BD9A9EFC2" modified="2009-10-13" version="1" precursor="true">MTKAAVISGIGSSVPASVVTNDMLAERLDTTDDWIRRLTGIQTRHWIEPGQATSDLAVEAGSRAIESAGGEPPQAVVLATITPDRPCPATAPEVASRLGLEGVAAFDVAAVCSGFVYGLATGTGLIAAGIAERVLVIGADTISTILDPTDRSTGVIFGDGAGAVMLRAGEADEPGALQALDLGSDGTGTDLITVPAGGSRQRSTKSVPPTTDTYLKMAGREVFRESVRRMVESCEAVLERTGWDAADVDRLVPHQANLRIMNSVADRLGMPRDRAVVDLDRVGNTSAASIPLALARAAAEGTVESGHRLLLTAFGGGLTWGSATLTWPDIKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVZ0</accession>
    <name>C7PVZ0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA_27 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786675.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2464"/>
    <dbReference type="EnsemblBacteria" id="ACU71382">
        <property type="protein sequence ID" value="ACU71382"/>
        <property type="gene ID" value="Caci_2464"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2464"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015046_1_0_11"/>
    <dbReference type="OMA" id="HREIEFP"/>
    <dbReference type="OrthoDB" id="370464at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038734">
        <property type="entry name" value="YhaN_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13514">
        <property type="entry name" value="AAA_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_27" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="817"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1051" mass="111822" checksum="C122BCDD22DE99DA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW66</accession>
    <name>C7PW66_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793043.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4451"/>
    <dbReference type="EnsemblBacteria" id="ACU73314">
        <property type="protein sequence ID" value="ACU73314"/>
        <property type="gene ID" value="Caci_4451"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4451"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079334_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="26495" checksum="2843F4387CE49CBE" modified="2009-10-13" version="1">MRILIIGGSGYVGTLMLPGLATEHEIRVLDLVPPQGDHEHVAGSATDPAALAAALEGMDAVVHGAMGRRSESHWPHPDVASAFEVNVASVYATLEAAHAAGVRRAVLIGSLSVFDEGQLIERQVDEETAPDAADVYGVTKRLAEQVGRIAAEAHGMTVTVLRLAFPTPDDVWPRWALPVVDEPIEIRRADGSLVPALAGSDLSAAVSAALSRDDGGYDVFHIVGADDSGRGWSTAKARDALGWVARRRYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWH1</accession>
    <name>C7PWH1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6397</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6397"/>
    <dbReference type="EnsemblBacteria" id="ACU75251">
        <property type="protein sequence ID" value="ACU75251"/>
        <property type="gene ID" value="Caci_6397"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6397"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_445989_0_0_11"/>
    <dbReference type="OMA" id="AMEIVFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="476"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="584"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="612" mass="65864" checksum="4B429B5817EC3C97" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWI3</accession>
    <name>C7PWI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794992.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6409"/>
    <dbReference type="EnsemblBacteria" id="ACU75263">
        <property type="protein sequence ID" value="ACU75263"/>
        <property type="gene ID" value="Caci_6409"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6409"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294872_0_0_11"/>
    <dbReference type="OMA" id="YLYCSSD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982249" evidence="5">
        <location>
            <begin position="31"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="6">
        <location>
            <begin position="243"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="409"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1027" mass="101103" checksum="A28D778D0FE2914E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX37</accession>
    <name>C7PX37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8471"/>
    <dbReference type="EnsemblBacteria" id="ACU77294">
        <property type="protein sequence ID" value="ACU77294"/>
        <property type="gene ID" value="Caci_8471"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8471"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_7_2_11"/>
    <dbReference type="OMA" id="MENDHVA"/>
    <dbReference type="OrthoDB" id="1772343at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13939" checksum="66CC3370E619750B" modified="2009-10-13" version="1">MAHPGAQPHSPADPPGHHPPHADPADRTLQDPVVDTAVGFLDLLAEPSRLRLLWALRDGELGVTALAETAGCTPTAASQHLAKLRLGGLVEQRADGRARLYRLRGGHIKRLVEEVVGHAEHAVRGIPYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX90</accession>
    <name>C7PX90_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0489"/>
    <dbReference type="EnsemblBacteria" id="ACU69441">
        <property type="protein sequence ID" value="ACU69441"/>
        <property type="gene ID" value="Caci_0489"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0489"/>
    <dbReference type="eggNOG" id="ENOG502Z7IU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031541_0_0_11"/>
    <dbReference type="OMA" id="DNAQAFM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013493">
        <property type="entry name" value="CHP02677"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09660">
        <property type="entry name" value="DUF2397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02677">
        <property type="entry name" value="TIGR02677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="58536" checksum="70BDA4038E07E945" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXC0</accession>
    <name>C7PXC0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0528"/>
    <dbReference type="EnsemblBacteria" id="ACU69471">
        <property type="protein sequence ID" value="ACU69471"/>
        <property type="gene ID" value="Caci_0528"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0528"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OrthoDB" id="1337662at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="29344" checksum="68BE4F24D9FF2A16" modified="2009-10-13" version="1">MNGAPDWITADADTERPSIARFYDYLLGGTHHLEVDRELGRKAIRAAPGLILLMRENRKFLRRAVKCALDAGIDQFLDIGSGIPARGSIHETARKAGSRARVAYVDIDPVAVSEGKAILAGDPEGVSVLGDVFEPAAILENPEVRALIDLDRPVVLLILNVIHFFPDSKVLPVLETYRHRLVSGSMLGLSVAMDGTTGAEAIDELYRQEYEGFTLRSREQIEALFGDFELLEPGVVYPPEWRPEDPGRTVVNPERYSSLVGVARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXD8</accession>
    <name>C7PXD8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784784.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0551"/>
    <dbReference type="EnsemblBacteria" id="ACU69489">
        <property type="protein sequence ID" value="ACU69489"/>
        <property type="gene ID" value="Caci_0551"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0551"/>
    <dbReference type="eggNOG" id="COG3221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090617_0_0_11"/>
    <dbReference type="OMA" id="QVQLAWF"/>
    <dbReference type="OrthoDB" id="988224at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="31585" checksum="41E2809A08114CEF" modified="2009-10-13" version="1">MSNRVLLGAVAYDSKVVTIWDGFRQWFRDRDLDFDYVLYSHYERQIEDLVEGHIDVAWHSPLAWVRTVRLARARSVGVRAVVMRDSDRDLVSAVLVRADSDLASLDDLRGRSVATGAIDSPQAHLLPLSMLREAGLRPDVDFKVSRFDVRVGLHGDHVGGERDAAVALRSGLVDAACMLDANTLLFSREGTLPAGSVRVLAKTEPFDHCTMAVGPGADKSTVDRFTALLLGMAYDDPTVRPLFDLEGLKQWLPARTDRYSALERAVDELGFLDAEGKLCADDYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY40</accession>
    <name>C7PY40_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase like protein, AhpD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793229.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4639"/>
    <dbReference type="EnsemblBacteria" id="ACU73500">
        <property type="protein sequence ID" value="ACU73500"/>
        <property type="gene ID" value="Caci_4639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4639"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OMA" id="GCSVCID"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="17"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="16268" checksum="2DA79A256247D1AE" modified="2009-10-13" version="1">MEARIQNPAVILDASGAIQQLYKAVNSGGVEPAVLELVHLRASQINGCAPCVFSGMGNMRRMKESEERIGLVAVWHDAPFFTEEEKAALALAEAATRLADNPEGVSDAVWDGAAQFFDEKQLAAIVMMVALTNLFNRLNHTTRQVAGQAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY55</accession>
    <name>C7PY55_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase domain protein FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795074.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6495"/>
    <dbReference type="EnsemblBacteria" id="ACU75345">
        <property type="protein sequence ID" value="ACU75345"/>
        <property type="gene ID" value="Caci_6495"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6495"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059021_1_4_11"/>
    <dbReference type="OMA" id="VITCRNT"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="18"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="17605" checksum="5B826CA0E1E866FC" modified="2009-10-13" version="1">MTGTVARGQDGAAFRAAMSRWASGVAVVTTRDAAGRCHGFTATSFTSVSLDPPMVLVCLDRAASCAEAFAVATTYAVHILHGGQEELARRFARKGGDKFADLPVRVFGTPVLPDSLAVLECRVADRFAAGDHTVLLGLVRRAESFAGAPLLYHDRAFADVAARVSAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY87</accession>
    <name>C7PY87_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795106.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6529"/>
    <dbReference type="EnsemblBacteria" id="ACU75377">
        <property type="protein sequence ID" value="ACU75377"/>
        <property type="gene ID" value="Caci_6529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6529"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="VILAYDC"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="224" mass="23943" checksum="8E277A74729CAE69" modified="2009-10-13" version="1">MTGVSVLLADDQPLSRHGLAMILQAQGDIEVVGQAADGVEAVELAAALQPAIVLMDVRMPRLDGIAATRQIIARALPTRVIVLTTFDLDDYAFEALRAGASGFLLKNSRPDDLAAAIRAVAAGDAVIAPSTTRRLLDAYADRFTAPSDPPAGASDPSAPLESLTRREREVFDQMVSGLTNKEIAQQLALSETTVKTHVVRILAKLAVRDRVQAVIYAYETGYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYL2</accession>
    <name>C7PYL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797059.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8511"/>
    <dbReference type="EnsemblBacteria" id="ACU77334">
        <property type="protein sequence ID" value="ACU77334"/>
        <property type="gene ID" value="Caci_8511"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8511"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_36_2_11"/>
    <dbReference type="OMA" id="FVFDQHD"/>
    <dbReference type="OrthoDB" id="1591999at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="29"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="44599" checksum="81E0897FE0B0BD9D" modified="2009-10-13" version="1">MTERIRTPHAVLVLLNLPVPDDQRAWSQALALRDDGARVTVVCPAIRGRKPGRERIDGIEVIRFRSFEGQGPLATAAEGFWTAAAAGEAARGALRSSPASARMLQIGNPPDLLFPLAWWARRTGIRTVYDQRDVVPVLAASRAGFSRLTPLFLAAERRMITTADVVITPSEEQRARILSRYGRDALIIRTAEVPAEKEAEPDAAAVNETDAAAVAEPDDAAVAPDSAPTALAPTLTIGYLGVIGEQDGLTDLLDAVALLRADGLTGFRVEVAGDGPALPAARAHATRLGLDALVAFHGWLGPGAVDAFLGRIDAMAVPDPDNPFNHFCAMNKVTHAMARGIPIALRPLRENVRLTAGHAYEAADMTIRAFADALAALLKDTPAGRSDIAAEARATFEAHHSWPHHAPRYVAAVSPTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYZ6</accession>
    <name>C7PYZ6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Microbial collagenase</fullName>
            <ecNumber evidence="4">3.4.24.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_0616</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Digestion of native collagen in the triple helical region at Xaa-|-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'.</text>
            <dbReference type="EC" id="3.4.24.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.24.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784847.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0616"/>
    <dbReference type="EnsemblBacteria" id="ACU69552">
        <property type="protein sequence ID" value="ACU69552"/>
        <property type="gene ID" value="Caci_0616"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0616"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011878_0_0_11"/>
    <dbReference type="OMA" id="QNDSRMQ"/>
    <dbReference type="OrthoDB" id="43759at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013661">
        <property type="entry name" value="Peptidase_M9_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002169">
        <property type="entry name" value="Peptidase_M9A/M9B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01752">
        <property type="entry name" value="Peptidase_M9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08453">
        <property type="entry name" value="Peptidase_M9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00931">
        <property type="entry name" value="MICOLLPTASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 13" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982712" description="Microbial collagenase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M9_N" evidence="14">
        <location>
            <begin position="129"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="41"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU69552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="787" mass="82862" checksum="B7B60EDF1C999A4A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ69</accession>
    <name>C7PZ69_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase dimerisation and phosphoacceptor region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0690"/>
    <dbReference type="EnsemblBacteria" id="ACU69625">
        <property type="protein sequence ID" value="ACU69625"/>
        <property type="gene ID" value="Caci_0690"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0690"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_355598_0_0_11"/>
    <dbReference type="OMA" id="GHTEPLG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="512"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="699" mass="71686" checksum="0B3F4D8EA1A43B09" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ90</accession>
    <name>C7PZ90_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786840.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2630"/>
    <dbReference type="EnsemblBacteria" id="ACU71547">
        <property type="protein sequence ID" value="ACU71547"/>
        <property type="gene ID" value="Caci_2630"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2630"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_2_11"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="107" mass="11252" checksum="D428A6F06B6800DC" modified="2009-10-13" version="1">MPEFSYRVREQDQVSVVEVSGDVDMSVAGQLSEALEQLVPVGDVVLDCTGVTFFDSMGLRVAVNALNQAAQAGTAFSLVPSHTVARVLELAGVTSIFVIHDSVPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC1</accession>
    <name>C7PZC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71578">
        <property type="protein sequence ID" value="ACU71578"/>
        <property type="gene ID" value="Caci_2662"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2662"/>
    <dbReference type="HOGENOM" id="CLU_2506642_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9715" checksum="489D562410C80E6C" modified="2009-10-13" version="1">MTEDLPFLLREQAHDRVNEYKAEHQTDADADPPAEEDRLEPGPGQIHQERRRLQHAAEMAEEAHRRAKDNDGDDGDDRDDEAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZJ4</accession>
    <name>C7PZJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2737"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71651">
        <property type="protein sequence ID" value="ACU71651"/>
        <property type="gene ID" value="Caci_2737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2737"/>
    <dbReference type="eggNOG" id="COG1554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008552_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980479" evidence="2">
        <location>
            <begin position="36"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="1018"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1148" mass="118116" checksum="AFBF6142876721CD" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZJ6</accession>
    <name>C7PZJ6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular small neutral protease</fullName>
            <ecNumber evidence="3">3.4.24.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Snapalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes proteins with a preference for Tyr or Phe in the P1' position. Has no action on amino-acid p-nitroanilides.</text>
            <dbReference type="EC" id="3.4.24.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M7 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.77" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786946.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2739"/>
    <dbReference type="EnsemblBacteria" id="ACU71653">
        <property type="protein sequence ID" value="ACU71653"/>
        <property type="gene ID" value="Caci_2739"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2739"/>
    <dbReference type="eggNOG" id="COG5640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124996_0_0_11"/>
    <dbReference type="OMA" id="WNANVSN"/>
    <dbReference type="OrthoDB" id="1649119at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000013">
        <property type="entry name" value="Peptidase_M7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02031">
        <property type="entry name" value="Peptidase_M7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00787">
        <property type="entry name" value="NEUTRALPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982363" description="Extracellular small neutral protease" evidence="6">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="20491" checksum="A72BCBE417CD7BCA" modified="2009-10-13" version="1" precursor="true">MRIRPTARAFTLGACVLLPLAAAPVSMAATSQSALTPHASVRTVYYEASRAGTWKTDVATATAVWNSSVNDVKFVQATSAHPATVHLVATSGWPQTMTSRPGSGTVDLGQEAVSEGYSPPRIAAHELGHILGLPDNYNGDCAALMSGHSAGTACTNDHPDASEIASVESIFSGGFGPYSVVHVYRDEATTPSALVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT1</accession>
    <name>C7PZT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793325.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4735"/>
    <dbReference type="EnsemblBacteria" id="ACU73596">
        <property type="protein sequence ID" value="ACU73596"/>
        <property type="gene ID" value="Caci_4735"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4735"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_1_11"/>
    <dbReference type="OMA" id="QEADDVW"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="157" mass="16616" checksum="01CE48B7B13E0485" modified="2009-10-13" version="1">MRVTFTVNGRRAEADDVWEGESLLYVLRERVGLPGSKNACEQGECGSCTVYLDDVPVCSCLVAAGQVQDRQVRTVEGLADGDVLDPIQACFIKAGAVQCGFCTPGLLVQAHALIESNPTPSDPEIREALAGNLCRCTGYEKILDAVREAAATKAGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q090</accession>
    <name>C7Q090_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77423">
        <property type="protein sequence ID" value="ACU77423"/>
        <property type="gene ID" value="Caci_8604"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8604"/>
    <dbReference type="HOGENOM" id="CLU_2477676_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="87" mass="9828" checksum="D83CFD7D3AE02D92" modified="2009-10-13" version="1">MCFVSDRKPYNSDLSDGQWDLIRPVTEFERADGLLRAGQLCQILDVGTEPKHREGMRSRLKRLAARGILAETEPGLFALIAKTTLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0C4</accession>
    <name>C7Q0C4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Helix-turn-helix type 11 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797181.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8641"/>
    <dbReference type="EnsemblBacteria" id="ACU77457">
        <property type="protein sequence ID" value="ACU77457"/>
        <property type="gene ID" value="Caci_8641"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8641"/>
    <dbReference type="eggNOG" id="COG2378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041141_1_0_11"/>
    <dbReference type="OMA" id="PLHMEYW"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="35481" checksum="636C4C022F6D1561" modified="2009-10-13" version="1">MLETSARLLRLLSLFQARRDWTGGELAERLGVTTRTVRNDVERLRELGYPVEARPGVAGGYRLGSGATLPPLLLDDDEAVAVALGLRIAAAGAVAGIEETSLSALAKLQRILPARLRHRVESFGSHALAVPTHAPTVDPETLTTLALACRDHLMLHFDYEAHSGATSRRTTEPYRLIHRRQHWYLFAWDPSRADWRTFRADRIHPHTPPGPRFTPRPTPPDAEITTRVDTGVAQAPWRYKARVIVHAPATYVRTRIPTPITVEELPNGHSAFEPGSDNPERLALYLGMLEADFEVTDAPELAAAVERIIARYQRAIGNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q123</accession>
    <name>C7Q123_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786991.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2785"/>
    <dbReference type="EnsemblBacteria" id="ACU71698">
        <property type="protein sequence ID" value="ACU71698"/>
        <property type="gene ID" value="Caci_2785"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2785"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="MTAMVMA"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="91"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="32195" checksum="9222672B54095678" modified="2009-10-13" version="1">MATSTADPIDDRPAPRPPAPTGARRRRGGHAVLAGFILLAVFMIAPFAIVVMNAVKSKSDYAAHGPLALPHGIDFGNVKTFWNLVDFGHVLMNSVLISGCVALCAVLLSVLNAFALGIGRVRGRTWILLAFLIANLLPQEGLVYPLYWLAKQTNMYDSKLTVIIVFTVIQSAFGTYLLSSVLSAFPREILEAARMDGAGKWRLLWQVVVPVSRPTLVVLMTFFFIWTWNEFLLPLILLVSNENQTVPVALGVAQGEHIVDVTMQAASGLLGIVPAVVFFLIFQRTLTRGVTVGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q177</accession>
    <name>C7Q177_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2843"/>
    <dbReference type="EnsemblBacteria" id="ACU71752">
        <property type="protein sequence ID" value="ACU71752"/>
        <property type="gene ID" value="Caci_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2843"/>
    <dbReference type="HOGENOM" id="CLU_2128985_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="113" mass="12539" checksum="C1CC31B7EC0FC761" modified="2009-10-13" version="1">MADEATGLPHELADLGFEEVRVARVQPGVVIVLMTSKQITDEQAAVMHQQLSTLFEGHRVAILQDGLFLEVLRPTQDAPTQTQLEYKADAFDASGFMDEARKHVRMRGYGGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1B4</accession>
    <name>C7Q1B4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4782"/>
    <dbReference type="EnsemblBacteria" id="ACU73643">
        <property type="protein sequence ID" value="ACU73643"/>
        <property type="gene ID" value="Caci_4782"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4782"/>
    <dbReference type="eggNOG" id="ENOG502Z94V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031194_0_0_11"/>
    <dbReference type="OMA" id="FECGWSW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="543"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="622" mass="68270" checksum="FFE5D82FCD42DC76" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1D0</accession>
    <name>C7Q1D0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793388.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4798"/>
    <dbReference type="EnsemblBacteria" id="ACU73659">
        <property type="protein sequence ID" value="ACU73659"/>
        <property type="gene ID" value="Caci_4798"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4798"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_44_11"/>
    <dbReference type="OMA" id="YPWIVME"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="583" mass="61740" checksum="C1E6A0691502B245" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K6</accession>
    <name>C7Q1K6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-L-fucosidase</fullName>
            <ecNumber evidence="2">3.2.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793464.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4875"/>
    <dbReference type="CAZy" id="GH29">
        <property type="family name" value="Glycoside Hydrolase Family 29"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73735">
        <property type="protein sequence ID" value="ACU73735"/>
        <property type="gene ID" value="Caci_4875"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4875"/>
    <dbReference type="eggNOG" id="COG3669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_6_1_11"/>
    <dbReference type="OMA" id="PDFTYQE"/>
    <dbReference type="OrthoDB" id="439010at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="PTHR10030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="483" mass="54239" checksum="842F8C942426A7F3" modified="2009-10-13" version="1">MTLFTPTWASVDRHVAAPEWFQDAKFGIYHHWGAFSVPAFANEWYPRAMYYPDGAERQHHVETYGDPQTWPYHRFIEGADDRSGRFVKFAPTLASAGGRFDPHEWAQLIADAGARFAGPVAEHHDGFSMWDSRVNEWNSVAKGPQLDLLSLFAEAYREQGLKLLVAMHHAYHYTGYFEHVPPQPTRSLRKLYGQLSKPEHDRLWLDKLKEVIDLARPDIIYQDVNLDKIEEPIVLEFLAHYYNRAGEWGTEVVATYKDGLTDKGQVYDYERGGPKDLTHPYWLTDDILTVDSWSYKPDLVYVPVELILHSLIDRVSKNGGLLLNIAPTAEGVIPDEQRTLLLAIGDYLRRYGESVYETRAWTVYGEGPTEMGGGSFVPPVAGTARDIRFTRDKPGRILYATVLGWPAGGLTIATLAAGRFDLGSLRAIELIGPETDAYIPLSDYRQDAAGLHIALPQSAPFSAAAYVAKLTFDGPIPSLDSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2A3</accession>
    <name>C7Q2A3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_8827</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797364.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8827"/>
    <dbReference type="EnsemblBacteria" id="ACU77640">
        <property type="protein sequence ID" value="ACU77640"/>
        <property type="gene ID" value="Caci_8827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8827"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_12_1_11"/>
    <dbReference type="OMA" id="IEFARMM"/>
    <dbReference type="OrthoDB" id="357522at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01153">
        <property type="entry name" value="ACAD_fadE5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034188">
        <property type="entry name" value="FadE5-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="162"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="287"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="473"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU77640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="609" mass="66488" checksum="95342C7398098C7B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2F2</accession>
    <name>C7Q2F2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0861"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69794">
        <property type="protein sequence ID" value="ACU69794"/>
        <property type="gene ID" value="Caci_0861"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0861"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030021_0_0_11"/>
    <dbReference type="OMA" id="PVWISEF"/>
    <dbReference type="OrthoDB" id="1395441at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980546" evidence="4">
        <location>
            <begin position="29"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="5">
        <location>
            <begin position="107"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="485"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="642" mass="69014" checksum="A69CB72DD6734B62" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2L6</accession>
    <name>C7Q2L6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0926"/>
    <dbReference type="EnsemblBacteria" id="ACU69858">
        <property type="protein sequence ID" value="ACU69858"/>
        <property type="gene ID" value="Caci_0926"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0926"/>
    <dbReference type="eggNOG" id="COG1487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324448_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="22273" checksum="DC42059ECE31C174" modified="2009-10-13" version="1">MGESLSGLAAAAQSGAREFGERGSGGRESGERESGGGDQGSREFSAQDLTSRWLTVEQVLGRRIGQASALSAVEPAFPALDLVAADTAVASRWFTADPAPGKLAGRTVVLPFVAVAELATWPERLLWGHSRTEDLSLWADRRRMILGDDTVCRIWARITVAAQRAGSPPPANDSWIAAGCLSYGLPLATQDKRHYRYFADRYGLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2V6</accession>
    <name>C7Q2V6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787141.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2939"/>
    <dbReference type="EnsemblBacteria" id="ACU71848">
        <property type="protein sequence ID" value="ACU71848"/>
        <property type="gene ID" value="Caci_2939"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2939"/>
    <dbReference type="HOGENOM" id="CLU_2068875_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="118" mass="13153" checksum="700DFD90DBC726A6" modified="2009-10-13" version="1" precursor="true">MALWLTAIVVLGIIITAALAFRFFDRKDMRRTDLLQDAIAAANGDPRAAVAITALIELEYGGYGREHLRLITELAANKARLELARFDLKRLQAGVAVQQKSVGSLQHRLLETSKRWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2X2</accession>
    <name>C7Q2X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71864">
        <property type="protein sequence ID" value="ACU71864"/>
        <property type="gene ID" value="Caci_2955"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2955"/>
    <dbReference type="HOGENOM" id="CLU_1755549_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16925" checksum="68D3228CFE8A2FF1" modified="2009-10-13" version="1">MVSNRRTDGLNTVVTMKRRGTPTVPVSHVVAYKTPFETRVHFESVPLDVDQAHVVSERPYVSVTAYSWRLWPERQPVEDSWFIEVVAFIPEEAMSALDEALQRLDADIAAGRVVRGTHDALVEKDPFGRREAELELFHRAKIRELQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2X3</accession>
    <name>C7Q2X3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787158.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2956"/>
    <dbReference type="EnsemblBacteria" id="ACU71865">
        <property type="protein sequence ID" value="ACU71865"/>
        <property type="gene ID" value="Caci_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2956"/>
    <dbReference type="eggNOG" id="ENOG502Z7YZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071811_0_0_11"/>
    <dbReference type="OrthoDB" id="1520004at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="27273" checksum="04212DB13905CC43" modified="2009-10-13" version="1">MAKLNQIIAVEKSVKSRSYADITEAHHNVQKQALLSGISRTYQPKDEEGEQLPPESTRVQIGAEEILRFTSANMTRLFDVTATKDWANCEARADVMVDGQVLIAGVPVSYLLFLEKQLTDLHTFVKKLPVLDAAESWVHDPSTDSWKTEPVRTNRTKKVPRNHVKAEATEKHPAQVEVYYEDVTVGTWTTTKFSGALPAERVNALAARVEKLAHAVKFAREEANNHEVTDRRVGEDVFGYLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q319</accession>
    <name>C7Q319_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787204.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3002"/>
    <dbReference type="EnsemblBacteria" id="ACU71911">
        <property type="protein sequence ID" value="ACU71911"/>
        <property type="gene ID" value="Caci_3002"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3002"/>
    <dbReference type="HOGENOM" id="CLU_2045465_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="120" mass="13265" checksum="3ECB56474FC5306E" modified="2009-10-13" version="1">MTDIRAEAKDASDVVALLKREAERVQREMAAVDPQAGLADLKQRLKVPKPFVGYLVENADFATPVRKKTSWLFHLPPLFHGIADAKAQRAGYQAMASRSQPKVIFRVTVTFEVVEDGGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3K9</accession>
    <name>C7Q3K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_6943</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6943"/>
    <dbReference type="EnsemblBacteria" id="ACU75774">
        <property type="protein sequence ID" value="ACU75774"/>
        <property type="gene ID" value="Caci_6943"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6943"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_305183_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="715"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="796"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="833"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="866"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="941"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="356"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="631"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="389"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU75774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="972" mass="104055" checksum="5D25A00DE202C8C0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3X2</accession>
    <name>C7Q3X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797454.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8917"/>
    <dbReference type="EnsemblBacteria" id="ACU77730">
        <property type="protein sequence ID" value="ACU77730"/>
        <property type="gene ID" value="Caci_8917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8917"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1265051_0_0_11"/>
    <dbReference type="OMA" id="IFIHAAP"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="99"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="23139" checksum="8FA1AB6F84EB71AA" modified="2009-10-13" version="1">MPDTIEDRLADLGGNLETAAAFRSPSLIRSRGEQIRVTHRRRMTAVASATAAVAIIGVGSLVALRPTGGHQGHTVSPSVSSSASKSAPPAKTTQATPIALIDLKQDQMTVYDKQGHIVKTVPVTAGTPANPSHVGTFTITAKQDQAEKVSDSGTDTSYRLTVHWVLTLDAGGPQIYAMPWDDGRFGKGNRTHGDIGMSTDMAQWLYTNVAIGDHIKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q467</accession>
    <name>C7Q467_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0999"/>
    <dbReference type="EnsemblBacteria" id="ACU69927">
        <property type="protein sequence ID" value="ACU69927"/>
        <property type="gene ID" value="Caci_0999"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0999"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440297_0_0_11"/>
    <dbReference type="OMA" id="ADGDAMW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="21491" checksum="5C9BD6ADA70FE604" modified="2009-10-13" version="1" precursor="true">MTSQQQNAPRSPARVKRGRVSPMATVAAITAAALVGVGVLAVQANGSAPNKAPSAVAAKQQPPVSTNQVGQPVSPAPDPALALPASSGTGKRMVYSLSKARIWLVGADEKVQMSAAVVPSTVIPAAGTYAVSKRIANNQSADRVAVQYEVLWGPKGDTTKFAMEAVSSLPGDQMPMKPEAKTGGVRLTQNDALAVWQFAVLQTPVVVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5I3</accession>
    <name>C7Q5I3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77794">
        <property type="protein sequence ID" value="ACU77794"/>
        <property type="gene ID" value="Caci_8981"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8981"/>
    <dbReference type="eggNOG" id="ENOG502ZS3W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_956222_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="30789" checksum="AC5A641C2782DA3C" modified="2009-10-13" version="1">MVFHDYAGWSGWVFEVDLSYVPDGGRLVPKARGYRAIPPVEAHKNVRKPPPKVVEEIKTAAEAQWGGGSGLLLLDMLKVDFPGFGSRDKARRARTVSRIYSAAQSSGFCPRKTLVELLDIPTKPTAAAGRVESKTLDNWLREARSEGYLPPFDPDRDLPAKWPWKRWEHPHHLEPRHTRRVLTLDGSVVEQPTPAGETLTVWLSPIELLGVNDEGQQIATLSVTAKWPDGTPLSGLDPVVGVTVAQAITEVAPRIIADLEQRFPGTEVTVKYRPPESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5V2</accession>
    <name>C7Q5V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1123"/>
    <dbReference type="EnsemblBacteria" id="ACU70049">
        <property type="protein sequence ID" value="ACU70049"/>
        <property type="gene ID" value="Caci_1123"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1123"/>
    <dbReference type="eggNOG" id="COG3336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054944_1_0_11"/>
    <dbReference type="OMA" id="GMPFHAF"/>
    <dbReference type="OrthoDB" id="1553593at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019108">
        <property type="entry name" value="Caa3_assmbl_CtaG-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09678">
        <property type="entry name" value="Caa3_CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="35011" checksum="3A6A644C830D41F6" modified="2009-10-13" version="1">MGDGMSGPGWMPEVPATLGRLLAWHPQPIPIEPLACLLVALLYVLGVWRLHRRGDRWQPGRTLAFLLGIATIVEVTATGIGGYGMQLMSIHMVQHMVLSMVSPVLLLLGAPITLTLRALPAAPHGRLGPREVLVHALHSRACKVITAPWFTLPLFVGSLYGLYFTSLFTTLMSTWWTHDLMLLHFLFVGLLFFYPILGVDPGPRRANPVLGILELFGGMPFHAFFGIAVMMSSSLTTTVFTHHPATWSGTALADEHAAGAIAWAFSEIPSVLVLLVLFMQWRRADTRAAVRRDRAADRDNDAELNAYNDYLAGLNRGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W6</accession>
    <name>C7Q5W6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_1137</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1137"/>
    <dbReference type="EnsemblBacteria" id="ACU70063">
        <property type="protein sequence ID" value="ACU70063"/>
        <property type="gene ID" value="Caci_1137"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1137"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_307311_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="755"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="874"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU70063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="962" mass="102575" checksum="DFA2EA67F21F3A09" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W7</accession>
    <name>C7Q5W7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785358.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1138"/>
    <dbReference type="EnsemblBacteria" id="ACU70064">
        <property type="protein sequence ID" value="ACU70064"/>
        <property type="gene ID" value="Caci_1138"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1138"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067079_1_0_11"/>
    <dbReference type="OMA" id="ATPARMY"/>
    <dbReference type="OrthoDB" id="1186918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006764">
        <property type="entry name" value="SAM_dep_MeTrfase_SAV2177_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04672">
        <property type="entry name" value="Methyltransf_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017393">
        <property type="entry name" value="MTase_SAV2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28544" checksum="B0EF1625CA441B9A" modified="2009-10-13" version="1">MSEAGWTSPEVDTEVATPARMYDYYLGGKDNFPADREAAEKVLKNMPKVRAFARANRAFLGRAVRSMAAENISQFLDVGIGLPGPGGTVASALAARPDAHVVGVDNDPIVLAHARARPVNAGGGAATIVAGDLRDPAAILADPQVRAMLDFERPIGVMLIAVLHFVSDDEKPYDIVKTLMDAVAPGSYLALTHVTGDFDQERLAVSAQAYEKSTAKLTVRSAKETAAFFDGMDLLDPGVVLLPRWRPDGPVPADADDIWMYGALGRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q602</accession>
    <name>C7Q602_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785393.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1174"/>
    <dbReference type="EnsemblBacteria" id="ACU70099">
        <property type="protein sequence ID" value="ACU70099"/>
        <property type="gene ID" value="Caci_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1174"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071824_0_0_11"/>
    <dbReference type="OMA" id="CHIGYVH"/>
    <dbReference type="OrthoDB" id="1311927at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="34762" checksum="6A84F0318576909D" modified="2009-10-13" version="1">MELSILYRGPLASCDYDCGYCPFAKRRDSPETLRADRAALERFVAWVIAQSEDQINVLFTPWGEGLTRSWYQRALVELSRLDHVGEVAIQTNLSSRTAWTAGADLDSLALWCTYHPDQVSYERFLGRCHELRDSGVRFSTGIVGLPEHLDAARRLRADLPDDVYLWVNAAEGHTYTDEEAEPWAEIDPLFPVSRFPHASQGHACRAGESVISVDGDGEVYRCHFVSRTEPTERLGNLYDGSYRQALRARLCPLTQCDCHIGYVHMPELGLYDTFAGGVLARIPAGATVLRPEPVLKPVPLLKSAGAAGTRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q622</accession>
    <name>C7Q622_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785413.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1194"/>
    <dbReference type="EnsemblBacteria" id="ACU70119">
        <property type="protein sequence ID" value="ACU70119"/>
        <property type="gene ID" value="Caci_1194"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1194"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063440_3_1_11"/>
    <dbReference type="OMA" id="PSDEGPH"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="12198" checksum="B3084ACDFF56875C" modified="2009-10-13" version="1">MDSTQLLKGVLDSAVLAVLVDEDGYGYDIVRRLRVAGFEDIGDASVYGTLRRLYANGYLTSYVVPSESGPHRKYYGVNASGRAQLKESTATWRAFASSMDRLLGAERGERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q646</accession>
    <name>C7Q646_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787345.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3143"/>
    <dbReference type="EnsemblBacteria" id="ACU72052">
        <property type="protein sequence ID" value="ACU72052"/>
        <property type="gene ID" value="Caci_3143"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3143"/>
    <dbReference type="eggNOG" id="COG4842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151185_3_2_11"/>
    <dbReference type="OMA" id="QNTSYFA"/>
    <dbReference type="OrthoDB" id="2011147at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="10743" checksum="A6810A69E792BAC6" modified="2009-10-13" version="1" precursor="true">MTADQISVNFGALQSSAGSLSAKAAALTSYLEELLQSLQPMKQTWVESNSSAGVAADQAETKLRQATNDIIATINQFSAKVNEAHDLQYALEQQNTSYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q724</accession>
    <name>C7Q724_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795765.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7208"/>
    <dbReference type="EnsemblBacteria" id="ACU76037">
        <property type="protein sequence ID" value="ACU76037"/>
        <property type="gene ID" value="Caci_7208"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7208"/>
    <dbReference type="eggNOG" id="COG4992">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_0_11"/>
    <dbReference type="OMA" id="VYSSMDR"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="49297" checksum="D785C7937C450355" modified="2009-10-13" version="1">MGFDLADLLAARRGEGYGLHAEYGNPQLARMLRTIGFDTVYEQAEGAFLIGADGQRYLDFLSGFGVFGLGRNHPVIRQALHQYLDAQYADLVQFDCALLAGVLAEQLVSKAPGMERAYFGNSGTEAVETALKFARCATGKPRVLYADHAFHGLTAGSLSANGAKEFRDGFGPLLPGGAVEFGDLAALEAELRKGDVAAFIVEPIQGKGVFLPPPGYLAQAQALVRKHKALLICDEVQTGLGRTGTFFAYESEGLEPDLVTVAKTLSGGFVPVGATLGKDWIFQKVYSSMDRVLVHDSTFGSTAMAMTAALATLSVLEDEELTANAARAGGQLTAGLQDMVGRYEMLADVRGRGLMIGIEFGKASSLRLKAGWSMLQAARKGLFSQMIVMSLYRRHRILTQVSGDFLEVVKLLPPLTIGEREVEQFLAAFEDVMRDAHKGTGMMWDFGKTLMKQARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7B2</accession>
    <name>C7Q7B2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785494.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1275"/>
    <dbReference type="EnsemblBacteria" id="ACU70200">
        <property type="protein sequence ID" value="ACU70200"/>
        <property type="gene ID" value="Caci_1275"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1275"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="GPIFYRL"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="23215" checksum="E9D5031D5F23B962" modified="2009-10-13" version="1">MASGSEDTPRSSPTPTAARTRGRPRNAGADTAILAATRALLAERGWPDLTIAEVASRAGVAKTTLYRRWPGKADLVVDAMAELFSHLEVLDRGSMLQDALATVGQYVELLQLPETQAALLALSAEADRDPSLRAKVIGKVIDPQRHLVYEAWERACRRGEVEGETDIDLIFDMICGTLVHRILIKGQPVDEDYLTRFVSVVLAGLAQLRLSGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7F1</accession>
    <name>C7Q7F1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785533.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1315"/>
    <dbReference type="EnsemblBacteria" id="ACU70239">
        <property type="protein sequence ID" value="ACU70239"/>
        <property type="gene ID" value="Caci_1315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1315"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_2_11"/>
    <dbReference type="OMA" id="FHVRDPF"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="29230" checksum="9E84EDE7E06A00DC" modified="2009-10-13" version="1">MEILRYTAFSSDPAGGNPAGVVLDARGTDDAAMLAAAAEVGYSETAFLMPTEQDRVMDVRYFSPLAEVPFCGHATIATAVAYAERHGAGDLILNTRAGTVPVHTTAGTAGKLTATLVSVPPKSQDLRGPVLAELLAILGWTASDLHDALPPRVAFGGAWHPILATPSRSRLTELDYDMDALRALMLREDWTTIDLLWRESPDVFQARNPFPVGGVFEDPATGAAAAAFGGYLRELDLIPVPATVTVHQGVDMGRPSLLTIGIPAGDGGISVSGTAVALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7K2</accession>
    <name>C7Q7K2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3288</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787488.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3288"/>
    <dbReference type="ESTHER" id="catad-c7q7k2">
        <property type="family name" value="Chlorophyllase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72195">
        <property type="protein sequence ID" value="ACU72195"/>
        <property type="gene ID" value="Caci_3288"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3288"/>
    <dbReference type="eggNOG" id="COG4188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066851_1_0_11"/>
    <dbReference type="OMA" id="RTIDRRD"/>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047746">
        <property type="term" value="F:chlorophyllase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017395">
        <property type="entry name" value="Chlorophyllase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07224">
        <property type="entry name" value="Chlorophyllase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32339" checksum="15988F4162F061B9" modified="2009-10-13" version="1">MSHLDSAIGAASSIVSVKPVILSAPERGDDLQVRVSAPVSGNALPVVVFSHGFGGSLDKYAPLADFWAAHGFVVVQPTHLDSRTLAVTPDDPRYPDIWRVRISDLTRVIDDLDTLVAAVPGLAERVDATRIAIAGHSWGAQTASALLGAGVLDAAGVPGEDFADKRVMAGVLLSLTGTGESLSPFAAENFPFMHPDFSDLSIPALIVTGDSDQSLLSTRGPDWFTDAYFMSPGAQHLLTLFGGEHSLGGIVGYSSAETTDENPERVALIQRVTTAYLRTVLAVDTESFAAAHAEMTQSSASVGRPDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7P3</accession>
    <name>C7Q7P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787529.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3329"/>
    <dbReference type="EnsemblBacteria" id="ACU72236">
        <property type="protein sequence ID" value="ACU72236"/>
        <property type="gene ID" value="Caci_3329"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3329"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_43_9_11"/>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="GAF-like_dom_sf"/>
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        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
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    </dbReference>
    <dbReference type="SMART" id="SM01012">
        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANTAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ANTAR" evidence="5">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="523"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="830" mass="87670" checksum="D2E9754AEECF4EE3" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7T9</accession>
    <name>C7Q7T9_CATAD</name>
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        <submittedName>
            <fullName evidence="7">Peptidase S53 propeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3376</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3376"/>
    <dbReference type="MEROPS" id="S53.004"/>
    <dbReference type="EnsemblBacteria" id="ACU72282">
        <property type="protein sequence ID" value="ACU72282"/>
        <property type="gene ID" value="Caci_3376"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3376"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_0_0_11"/>
    <dbReference type="OMA" id="HDEMKRM"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="S53_propep"/>
    </dbReference>
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        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
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        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983002" evidence="5">
        <location>
            <begin position="35"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="6">
        <location>
            <begin position="213"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="545" mass="55385" checksum="2F14370E5FB10612" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U4</accession>
    <name>C7Q7U4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5252</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5252"/>
    <dbReference type="EnsemblBacteria" id="ACU74111">
        <property type="protein sequence ID" value="ACU74111"/>
        <property type="gene ID" value="Caci_5252"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5252"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_3_11"/>
    <dbReference type="OMA" id="EKPNAGM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="32"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="44837" checksum="13BBF1DFDD556187" modified="2009-10-13" version="1">MVRAVTTSAGFPSESGSESRPESARESAPDVLAPATLGPVRLRNRIIKSATFEGATPDALVTDDLIAYHRRPAAGGVGMTTVAYLAVSPEGRTERRQIHWRPEAVPGLRTLTDAVHAEGAAVAAQIGHAGPVADARSNRAAALSCSPMLNPVTFRRTRAATAADIERITAAHARAARLAIESGFDSVEIHLGHNYFASAFLSPRLNKRDDQFGGSLANRAKVALGLARAVRDEVGDRIAVTAKLNMEDGYPGGLRIEDSLQVAQWLQRDGTLDALELTAGSSLMNPMYLFTGDVPLREFAAQFPPLPRLGIRLFGKKFLRSYPYQDTYLMERALRFRAELSLPLILLGGVTTRATMDRAMAAGFQYVAMARALLREPDLVNRIAADATTPSACTHCNRCMPTIYTGTRCPEISRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7V4</accession>
    <name>C7Q7V4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5262"/>
    <dbReference type="EnsemblBacteria" id="ACU74121">
        <property type="protein sequence ID" value="ACU74121"/>
        <property type="gene ID" value="Caci_5262"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5262"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_3_11"/>
    <dbReference type="OMA" id="GIWEINE"/>
    <dbReference type="OrthoDB" id="287662at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="282"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="42405" checksum="9C058104A8C0C392" modified="2009-10-13" version="1">MSNAYVYDAIRTPRGRGKQNGSLHTVKPISLMVGLMEEMQARHPNLDPALIEDVILGVVSPIGEQGSDIAKVSALAAGLPDTTAGVQLNRFCASGLEAVNTAAQKVASGLGEDLILAGGVESMSRVAMGSDGGAWFEDPQTAYDISFIPQGIGADLIATIEGFSRTEVDEFAVRSQELAAAARAAGHFKKSVVPVRDRNGLTILDEDEFIRPGTTVQTLSGLKPSFEAIGDLGGFDAVALQKYHWVEKIDHVHHAGNSSGIVDGAALVLIGNETAGRAAGLTPRARILSTAVSGADSTIMLTGPAPAAKKALAKAGLDIEDIDLVEINEAFAAVVLRFVREMGESDLPLEKVNVNGGAIAMGHPLGATGAMLIGTIVDELERRDLRRGLVTLCVGGGMGIATIVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q888</accession>
    <name>C7Q888_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7247"/>
    <dbReference type="EnsemblBacteria" id="ACU76076">
        <property type="protein sequence ID" value="ACU76076"/>
        <property type="gene ID" value="Caci_7247"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7247"/>
    <dbReference type="HOGENOM" id="CLU_899226_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="31844" checksum="E38C3936681F5781" modified="2009-10-13" version="1">MSRDRIDRMDHSAEDGEHGVEPESDLESESESESESDEALRSRLHARADLVTITTPPISAVRRRARQRRRRRGMAQALSGVVAACAVVAGIVAWSPGRDDAGGPAPASTVASSPSFPGTAPGATHPTAPSPSPPPSSRSASISDFLLASDLGAGWVPGSDGMPMVMDEVEMTSAEDACDNGAVRQGALEPALSSVSTQVENSPPGKATNSVMETVYNFRAGGGATAMQEIRAALETGCGAPQTTKLLASPQTVADEVLAYTFGDHRGVVFVRSGDLVAATGVAVVPSGQEGIAWIQALAKDVAVRLTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M9</accession>
    <name>C7Q8M9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785588.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1371"/>
    <dbReference type="EnsemblBacteria" id="ACU70294">
        <property type="protein sequence ID" value="ACU70294"/>
        <property type="gene ID" value="Caci_1371"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1371"/>
    <dbReference type="HOGENOM" id="CLU_1701064_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982902" evidence="1">
        <location>
            <begin position="28"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16497" checksum="738DA11DB89D5210" modified="2009-10-13" version="1" precursor="true">MSNNTKAGAAVAAIVLLLFLIVRPSSSGHHFKVTATEYDCNVKIADDPRPLNREILSTVALKCATPPKQTSLVLQLQYRKDGSSPWANDGDARAFTGVPGPDYTDINITQPCKAGNWRIQYQLQGVAAALGTNFQATPQYGNSKAISQSACDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q972</accession>
    <name>C7Q972_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787685.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3486"/>
    <dbReference type="EnsemblBacteria" id="ACU72392">
        <property type="protein sequence ID" value="ACU72392"/>
        <property type="gene ID" value="Caci_3486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3486"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_11"/>
    <dbReference type="OMA" id="ANEIVIC"/>
    <dbReference type="OrthoDB" id="1630092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="16176" checksum="55421C922D2A17E0" modified="2009-10-13" version="1">MTFTATRSYGILLVEDDAADAMLIQDALLERPSEHTITQVEDGVAALHHLNDPARPHPDLILMDLNMPRMNGRELLAVLKADQVLKAIPVVVLTTSAAPDDVSAAYQGHANAYITKPVNLDDFVSAVQSIDTFFLDTAARVPREGKPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Q6</accession>
    <name>C7Q9Q6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795953.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7399"/>
    <dbReference type="EnsemblBacteria" id="ACU76225">
        <property type="protein sequence ID" value="ACU76225"/>
        <property type="gene ID" value="Caci_7399"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7399"/>
    <dbReference type="HOGENOM" id="CLU_1076422_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27099" checksum="9AE0B4B59674F4E0" modified="2009-10-13" version="1" precursor="true">MNRIEQVAAPTPTSTPTPAPQPRLPRARRGGSGLAVAMAALAVPLMPGTAFGATSSTGGGGVARTEVPHARHHLHHFHHGPVLPDPGVMTLRAWTASGWSLTVPNRDNVPWLAAPAQPALPIDHPRPVVLPDGTHGEIAEYRVPHASSVPPAGARSRVLPQPLVPFAVPSNTKQMTVPSQQAVDIPNGVANHTQLPSENAVAASLSASPSCQRRGYPISQDRYMVAHLRPAADPMDVAVSPHRTACAARVDYLSQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z4</accession>
    <name>C7Q9Z4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70392">
        <property type="protein sequence ID" value="ACU70392"/>
        <property type="gene ID" value="Caci_1469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1469"/>
    <dbReference type="eggNOG" id="ENOG5032S2G">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119822_0_0_11"/>
    <dbReference type="OMA" id="SARYQEG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="18883" checksum="24915CF3D51B684A" modified="2009-10-13" version="1">MRIGTMDIGRKKRGVTGMKVAEALALRADAARRVDQLKARIVANARYQEGEEPSENAATLLAEAGTTLDHLEELIRRINRTNAAATIGPDGTLSDALARRDTLRLRHSVVTAAADAAAGKNTGYQRQLRSELKMLSALRVSALRAQSDALSREIREIDVRIQRANWEVDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAM0</accession>
    <name>C7QAM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792248.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3616"/>
    <dbReference type="EnsemblBacteria" id="ACU72519">
        <property type="protein sequence ID" value="ACU72519"/>
        <property type="gene ID" value="Caci_3616"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3616"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_1_11"/>
    <dbReference type="OMA" id="GRETECA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="861"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="923" mass="97875" checksum="46182398DF805513" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAM5</accession>
    <name>C7QAM5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3621"/>
    <dbReference type="ESTHER" id="catad-c7qam5">
        <property type="family name" value="CFTR-inhibitory-factor_Cif"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72524">
        <property type="protein sequence ID" value="ACU72524"/>
        <property type="gene ID" value="Caci_3621"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3621"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_11"/>
    <dbReference type="OMA" id="APFWDLY"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
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        <location>
            <begin position="37"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="75"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="35923" checksum="B47B4FCFBB47B0AD" modified="2009-10-13" version="1" precursor="true">MKYLHAVFRPGAVLALAAASAVGLVATTITTGAAHAATASSPTASSLEQMPAGFSEHKTDVGGIGIDYVIGGHGPTLVLLHGYPQTWYEWRDVMPALAEHYTVIAPDLPGAGRSDAPATGYDKKDLAADIHGLLAEIGHDHDIRLVGHDIGTMVAYSYAAAYPRDVTKLVLSEAPIPDPSIYTYPSLTADGPGAWHFGFFALTNGLPEQLISGREELWTSKFVDDLEVVKGAVTPNDIDVFSSYLKDPAHLEAGLQWFRTLPQDMTNDAVYQKTKLTMPVLAIGASGSLGKAVPDQVRQYAKHVTGVVVPDSGHWMYEEHPAEMAHILLDFLGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAP3</accession>
    <name>C7QAP3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA_27 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5507"/>
    <dbReference type="EnsemblBacteria" id="ACU74366">
        <property type="protein sequence ID" value="ACU74366"/>
        <property type="gene ID" value="Caci_5507"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5507"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4717">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006135_0_0_11"/>
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    <dbReference type="Proteomes" id="UP000000851">
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038734">
        <property type="entry name" value="YhaN_AAA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="711"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="846"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1160" mass="127574" checksum="CA8C75B517750DB1" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY2</accession>
    <name>C7QBY2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3699"/>
    <dbReference type="EnsemblBacteria" id="ACU72601">
        <property type="protein sequence ID" value="ACU72601"/>
        <property type="gene ID" value="Caci_3699"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3699"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028885_2_0_11"/>
    <dbReference type="OMA" id="AKENCVE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13751">
        <property type="entry name" value="DDE_Tnp_1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="2">
        <location>
            <begin position="55"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Tnp_DDE_dom" evidence="3">
        <location>
            <begin position="419"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="680" mass="73992" checksum="0A1300D68A646835" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC64</accession>
    <name>C7QC64_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794241.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5653"/>
    <dbReference type="ESTHER" id="catad-c7qc64">
        <property type="family name" value="HNLyase_Bact"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74512">
        <property type="protein sequence ID" value="ACU74512"/>
        <property type="gene ID" value="Caci_5653"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5653"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082729_0_0_11"/>
    <dbReference type="OMA" id="WFPPEVL"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25649" checksum="7394D1A1A724A439" modified="2009-10-13" version="1">MPPTPLLIMVHSPLVGPATWQPVARLLHGRHDVMVPSLHGIAAGPGPYARRIAEVVARDARDTHADEIVLIGHSGAGAYLPAIVDAVDECVIGIAFVDAQLPRPGLSDFDASPPDFREALTAMAQDGMLPPWDRWFPPEVLTELIPQAEQREAFLSELHPIALAYFQEPAPRTESWSATQCTYLQLSESYTYQADRAEALGWPTTRLAADHLSLVTDPEPVADFLSEFARTLANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC92</accession>
    <name>C7QC92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5682</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5682"/>
    <dbReference type="EnsemblBacteria" id="ACU74540">
        <property type="protein sequence ID" value="ACU74540"/>
        <property type="gene ID" value="Caci_5682"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5682"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="YITIVGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27593" checksum="FB2F919C70A615B4" modified="2009-10-13" version="1">MSDQATTIPGPRTEPSSAEGAPLLELRSVEVAYGGIVALKGIDLEVRQGEIVALLGANGAGKTTTLRTISGLLKPRSGEVLYAGEALTGIPAHKIVQLGIGHSPEGRRIFSRMTVLENLQMGAYRFKSVAQADLDQVFELFPRLHERRTQLGGNLSGGEQQMLAIGRAMMGKPSLLLLDEPSMGLAPLIVAQIFEIIERINGLGTTILLVEQNAAQALKLADRGYVLETGEVRMSAPASELLNDPRVREAYLGEVAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF3</accession>
    <name>C7QCF3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein TetR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794330.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5743"/>
    <dbReference type="EnsemblBacteria" id="ACU74601">
        <property type="protein sequence ID" value="ACU74601"/>
        <property type="gene ID" value="Caci_5743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5743"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_19_2_11"/>
    <dbReference type="OMA" id="PSYWARF"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="22456" checksum="9779946611AECC3C" modified="2009-10-13" version="1">MRRVSARISILEAAERRFAEDGIEAVSLRQIAAESGQRNTSAVAYHFGTRAALVGALYEHRMAPINARRLEFLDAHPDAGVATYVRALVEPLAETLTDAEKAGRPSWYLRFLAEAMRYPEYDPASVAVALERPEASSIRALISGLQTATAPLRLPPGVFAERMRLLALLVITSLADRERHPGTGVGTETLIAAGAAILADGPTSTHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD03</accession>
    <name>C7QD03_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786007.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1792"/>
    <dbReference type="EnsemblBacteria" id="ACU70713">
        <property type="protein sequence ID" value="ACU70713"/>
        <property type="gene ID" value="Caci_1792"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1792"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047003_2_0_11"/>
    <dbReference type="OMA" id="WPAVAIS"/>
    <dbReference type="OrthoDB" id="1819400at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="377" mass="41244" checksum="D0B00FD1D4D7E449" modified="2009-10-13" version="1">MAPTTLTRDTLNRTLLARQHLLTPRSGSLAETVEAIGAIQAQYWPAVAISLFTRHDGATLAAVYDAFERRELVVGSSIRGTVHAVSRAEHPLYAAVSEATNADVLTARDEAKDPGMHALRAEVLEFAADKPRAAAEFAEFAEQWIEKHPGRMSAANLEYHQSRNWRPIYRSNALIRFPADGRWSPATGPKTFLYSPERAADTGAAIAALVRRHLGAFGPAAADDVALWLGLKVSVARAVLGGFSDLVTYADEAGRTLYDLPDGEITDAETKAPPRLLPRFDSILLAHNAKHRQRIISREYWERVYNGKNLQILPSFLVGGYVAGIWSLEAKKKLATLTLEPFHKLGKADAKALGAEAERVLRLQAPDSASYAVEFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD8</accession>
    <name>C7QDD8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Parallel beta-helix repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3832"/>
    <dbReference type="EnsemblBacteria" id="ACU72731">
        <property type="protein sequence ID" value="ACU72731"/>
        <property type="gene ID" value="Caci_3832"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3832"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_329753_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="3">
        <location>
            <begin position="648"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="830"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="870" mass="87446" checksum="205295AE1146A9C6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDE4</accession>
    <name>C7QDE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3839"/>
    <dbReference type="EnsemblBacteria" id="ACU72737">
        <property type="protein sequence ID" value="ACU72737"/>
        <property type="gene ID" value="Caci_3839"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3839"/>
    <dbReference type="eggNOG" id="COG5361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027269_2_0_11"/>
    <dbReference type="OMA" id="VNTPAMA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010621">
        <property type="entry name" value="DUF1214"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037049">
        <property type="entry name" value="DUF1214_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010679">
        <property type="entry name" value="DUF1254"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037050">
        <property type="entry name" value="DUF1254_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06742">
        <property type="entry name" value="DUF1214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06863">
        <property type="entry name" value="DUF1254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1254" evidence="2">
        <location>
            <begin position="76"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1214" evidence="1">
        <location>
            <begin position="355"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="476" mass="53229" checksum="8206074E21024D92" modified="2009-10-13" version="1">MHASRPDAVADAAPPLVRQINDGRWLDQREAEELRSELFFHRAVHAYLTMLPALNVIGMRDGSEGAFGAGYHVLPVWKDRMDSRTWVPTPNADVIYSMGYLDLGETGPLVVNAPANVIGMFTDFFQRTITDVGAIGPDRARGGLYLLLPPGYDGHVPNGYFTFRSSTFNVFLFFRTIMGKGDGGPDPSVGAATAERTRIYPLWEEEKDVLPMQFPNASGVRVNMMYPTDFSYWTILKEFVDFEPVGAIVPELRGVLASIGIVKGEPFAPNAWQREQLERAVRVAPRMTLALAQLGRDDQRNLYYTDRQWEQAWCGGTAEWMQASYLDINARSRFFQYAYSSAPAMVVHSTGAGSKYPYSARDADGAFLEGAKTYRLHLPPNPPADLFWAVTAYNITDGTMPETEQLLPSTNSYYDIPKNDDESVDVWFGPRKPDGVADHAFIQTVPDRNFVVALRLYGTAPAFYDQTWKPDDIVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDU5</accession>
    <name>C7QDU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-oxalocrotonate tautomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794448.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5861"/>
    <dbReference type="EnsemblBacteria" id="ACU74719">
        <property type="protein sequence ID" value="ACU74719"/>
        <property type="gene ID" value="Caci_5861"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5861"/>
    <dbReference type="eggNOG" id="COG1942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148073_5_3_11"/>
    <dbReference type="OMA" id="VQVWIHE"/>
    <dbReference type="OrthoDB" id="2013680at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004370">
        <property type="entry name" value="4-oxalocrotonate_tautomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01361">
        <property type="entry name" value="Tautomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="64" mass="7091" checksum="00BA645F1CC8B985" modified="2009-10-13" version="1">MPSVTIQQMPKTAEQKRELVSRITDAMVDVYKAPAETVHVWFQEVTAEDYAAGGVVLADKLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE52</accession>
    <name>C7QE52_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796365.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7816"/>
    <dbReference type="EnsemblBacteria" id="ACU76640">
        <property type="protein sequence ID" value="ACU76640"/>
        <property type="gene ID" value="Caci_7816"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7816"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_11_2_11"/>
    <dbReference type="OMA" id="WRGIAGF"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="23570" checksum="89FC5ADB7AC990EA" modified="2009-10-13" version="1">MTTTDAAYADSATSRQRSARLPRSARRNQLLGAAEEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLELYLALLDKHCDALVTQVRLALDSTTDNKLRVAATIGAYFDYVEHESGAFRLVFESDLNNEAAVRERTQRVTQECAEAIRDVIATDTGLSDEESMLLAVGLTGIAHVTARYWLSSGGGQIPRDAAARIVSQLAWRGIGNFPRKDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEN3</accession>
    <name>C7QEN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3917"/>
    <dbReference type="EnsemblBacteria" id="ACU72803">
        <property type="protein sequence ID" value="ACU72803"/>
        <property type="gene ID" value="Caci_3917"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3917"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_391674_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021889">
        <property type="entry name" value="DUF3500"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37489">
        <property type="entry name" value="PTHR37489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12006">
        <property type="entry name" value="DUF3500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="704" mass="77685" checksum="382DFBE434137BCA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEX6</accession>
    <name>C7QEX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794463.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5876"/>
    <dbReference type="EnsemblBacteria" id="ACU74734">
        <property type="protein sequence ID" value="ACU74734"/>
        <property type="gene ID" value="Caci_5876"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5876"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="HLLWLAH"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="33759" checksum="B5FC1606EEE0F34F" modified="2009-10-13" version="1">MTPRTAAPPPAIAVQDLRKRFGTTAALDGMSFDVAAGKVTGFVGPNGAGKSTTMRVVLGLDTPDEGQALIGGVPYAKLRRPLGHIGALLDAAALQPGRSARNHLLWLAHSQGLGTKRVDEVVEQSGLGEAIRRKAGGYSLGMRQRLGIAAAMLGDPPVVMLDEPFNGLDPEGIVWIRGYLKALAAEGRAVLVSSHLMSELEGCADHLVVAGRGKVIADTGVAELIARSSGGRVVLRTSARAEATTALANAGGTVAVTGPDQLTVDGVAAENVVRLLNSGGVPFAEVSAHRASLEEAYMDLTRDSVEFRAATAATSTATTAGIDGTDGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF59</accession>
    <name>C7QF59_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794546.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5959"/>
    <dbReference type="EnsemblBacteria" id="ACU74817">
        <property type="protein sequence ID" value="ACU74817"/>
        <property type="gene ID" value="Caci_5959"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5959"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077964_0_1_11"/>
    <dbReference type="OMA" id="CPCLDWS"/>
    <dbReference type="OrthoDB" id="1948031at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26655" checksum="59C47FF447BDB3CA" modified="2009-10-13" version="1">MSTTGPVTTDAASPANPLLAGADLAAIARLLADGTRATFCLALLDGRAWTPTELARHAGVAASTATEHLNAMVAGGLLAEERQGRHRYVRLADQQIAELIETLAAAAPVRSAPPPRTLSADSRRRALAHARTCYDHLAGRVGVAIADAMTERELVDWEHGLSLTPDGARWLAELGIEVPTAAKRPALRPCLDWTERRPHLAGAVGAALCGHALDKGWIKRVGTTRAVLVTPAGREILAARLGLSEQVLTPSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ5</accession>
    <name>C7QFQ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784289.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0039"/>
    <dbReference type="MEROPS" id="C26.955"/>
    <dbReference type="EnsemblBacteria" id="ACU68994">
        <property type="protein sequence ID" value="ACU68994"/>
        <property type="gene ID" value="Caci_0039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0039"/>
    <dbReference type="eggNOG" id="COG0512">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_1_2_11"/>
    <dbReference type="OMA" id="TEHGHAM"/>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU68994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22337" checksum="FBB49A6780748BB5" modified="2009-10-13" version="1">MAARILVVDNYDSFVYNLVQYLYQLGAECEVVRNDAIGVEAAHDYDGVLLSPGPGTPEEAGVCVAMTGYAEQHRIPVFGVCLGLQSIAVAHGAVVGRAPELLHGKTSKVTHDGAGVFQGLPDPFTATRYHSLAIEPETLPQDLLVTARTDSGVIMGIRHRELPVEAVQFHPESVLTEGGHRMLANWLTVCGDAGAVERSAGLAPVVLSAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR8</accession>
    <name>C7QFR8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0052</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0052"/>
    <dbReference type="EnsemblBacteria" id="ACU69007">
        <property type="protein sequence ID" value="ACU69007"/>
        <property type="gene ID" value="Caci_0052"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0052"/>
    <dbReference type="eggNOG" id="COG4962">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005379_8_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022399">
        <property type="entry name" value="HlxAse/secretion_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03819">
        <property type="entry name" value="heli_sec_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981608" evidence="3">
        <location>
            <begin position="19"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="103"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="492" mass="52326" checksum="FE33E329C92A13BB" modified="2009-10-13" version="1" precursor="true">MNALSSSPMSMPSPMSSPSPMSSPSPLSPVPLPGAERLRLNAALVDRVRTRLATPPVRVDMQAILAALRAEGCMLDGRDLRAAAYQVRSELTGAGVLDRYLADPEVTDVLVNAPDSVWIERAGTLSRADVRFPDEAAVRRLAQRLAAHAGRRLDDAAPCVDGILPDGARLHAVLPPIAARGTLISLRVPPRRAFTVDQLTAGGLTTEHGARLLRAVASEKVSYLVTGGTGSGKTTLLGALLGLVPGDERIVITEECTEVVVDHPHVARLQCRIANQENRGAVNLRTLVRQALRMRPDRVVVGEVRGPEVLELLAAMNTGHDGCAATMHANGVEDVVARVEALAAPAGMERSALHAQLNSAVQVVVHLVRDKGKRRLASIGVIDRGFGETEVLPAVDFDDTGKATYGPGSDRLSFLLGFEVRESTDEAPKAKPPPPRLPVDDLEKLAGWEEALAVADRLLPVLKNAANGGDSHVDEPFVADYGPSPTRRGGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFY7</accession>
    <name>C7QFY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2044</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786257.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2044"/>
    <dbReference type="EnsemblBacteria" id="ACU70964">
        <property type="protein sequence ID" value="ACU70964"/>
        <property type="gene ID" value="Caci_2044"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2044"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_8_1_11"/>
    <dbReference type="OMA" id="WTRTRER"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="23662" checksum="15B35B54ABC542EF" modified="2009-10-13" version="1">MTPPPADPRTPGEPTQERARRTRRAIALAAAECFAEVGYAVATTSEIAARAGVTKGALAFHFPAKAAIAAAIVEECYEEWPSLIQEATGRHARVVDLLGDVFARVAAQIREDPIVRATVRLQAERSQVAEPMRMPYVDWIATSTTLFRTAADHGELRPGLDPAALARAAIAGFVGVQHMSGVLNAHADVIERVTEWWAVMAAGIAADGAEGADAADGTDDHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG11</accession>
    <name>C7QG11_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP oxidoreductase coenzyme F420-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786281.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2069"/>
    <dbReference type="EnsemblBacteria" id="ACU70988">
        <property type="protein sequence ID" value="ACU70988"/>
        <property type="gene ID" value="Caci_2069"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2069"/>
    <dbReference type="eggNOG" id="COG2085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076368_2_0_11"/>
    <dbReference type="OMA" id="FVPHVIR"/>
    <dbReference type="OrthoDB" id="1768241at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="3"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="20228" checksum="0E5E72E4D1CC57B8" modified="2009-10-13" version="1">MTTIAVLGKGRVGGALADGFRRAGHQVAVGDSAPGSAEQAVGSAEIVVNAAPGGSSLERLTALRESLRGKILVDVSNATRSGADGMPSELMYPGSSLAEQVQAALPDTRVVKALNTMLYSVMAAPGTLSQPPTAFLSGEDAQAKQVVSALLGDLGWQPEWIIDLGGVQSARATEAVILLVPHVIRASGFAPFAVSIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG17</accession>
    <name>C7QG17_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786287.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2075"/>
    <dbReference type="EnsemblBacteria" id="ACU70994">
        <property type="protein sequence ID" value="ACU70994"/>
        <property type="gene ID" value="Caci_2075"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2075"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_444601_0_0_11"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="614" mass="68094" checksum="C15F169F5D62BF6A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG18</accession>
    <name>C7QG18_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA ATPase central domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786288.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2076"/>
    <dbReference type="EnsemblBacteria" id="ACU70995">
        <property type="protein sequence ID" value="ACU70995"/>
        <property type="gene ID" value="Caci_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2076"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_15_11"/>
    <dbReference type="OMA" id="MWIGNSE"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="223"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="49837" checksum="166B27ECE07C8176" modified="2009-10-13" version="1">MADGESPLIKALRQAVRSAPEQAEFRVALAEALIGAGDTQGAIVELGEALRLEPGSAQARALMLAALSRGTAAEGGEAATVAVPAQAAPAGQATPTVQATPVAQAMPAAQATPIAQADQHQAEESQPTEEDPAASKDPGFDWSAAEAELGDIAPPPRFTAASKPLAADDAGEDPEGVPAHDVERPALTLADVGGLADVKERLQVSFLAPMRNPELRKIYGKSLRGGLLLYGPPGCGKTFIARAVAGEIGASFISVGISEVLELWFGASEKNLSELFELARRQTPCVLFFDELDALGQRRSQTRSSMMRTVVNQFLTELDSVGADNEGVFVLGATNAPWDVDPALRRPGRFDRTVLVLPPDAPAREDILQYHLRDRPIAGIDLESLVARTDGFSGADLAYLCESATENALIDAVRSGEVRMMGMADFEAALKDVRPSTGPWFDAARSVALFANEGGAYDDLAAYFKNHKGAKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK2</accession>
    <name>C7QGK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794611.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6025"/>
    <dbReference type="EnsemblBacteria" id="ACU74882">
        <property type="protein sequence ID" value="ACU74882"/>
        <property type="gene ID" value="Caci_6025"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6025"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033863_20_1_11"/>
    <dbReference type="OMA" id="NTLTWPV"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="143"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="33101" checksum="E8DB057136F05596" modified="2009-10-13" version="1" precursor="true">MRNPRHIALALAVVVIWGVNFVAIGHALEGFPPILLAALRFALTGTAALFFPRPKEVRWYWIAGISAFMFFGQYVLLFTAMAHGMPDGLASLVLQSQAPFTVLAAALLLGEKTGPRQVAGIAAAVAGLVVIGAGRGGNVPLSSLLLAVGAGASWALGSICNRKAGATNGFALMVWASLYAAPPLFLTSLLSEGPHRIGHAFAHLHAGPVVGLLYVVLLSTFVGMGAWVVLITKYPASAVAPYTLGVPPVGILAALIANGERMTALEIAGSLVVLGGLVAIVWPRRSARGTSARRFRRPRIVPDPSVAAATVEESTHAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGP7</accession>
    <name>C7QGP7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794656.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6070"/>
    <dbReference type="EnsemblBacteria" id="ACU74927">
        <property type="protein sequence ID" value="ACU74927"/>
        <property type="gene ID" value="Caci_6070"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6070"/>
    <dbReference type="eggNOG" id="ENOG5031XIT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124041_4_0_11"/>
    <dbReference type="OMA" id="KYEVFLF"/>
    <dbReference type="OrthoDB" id="1862071at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14007" checksum="1CC846C10E49EFD6" modified="2009-10-13" version="1">MSTTIAAALTDLLLTPGLTLEEALDRHFDPAYRQRTDGVWADRAGFAEHIAHLRGVVADGTIRVHDELGEGAAYAERHTVDVVKTDGSTASHEVYVFAERAADGRFLRLEEVTLMLSGSDADRGLGSARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV7</accession>
    <name>C7QGV7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7984</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796532.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7984"/>
    <dbReference type="EnsemblBacteria" id="ACU76807">
        <property type="protein sequence ID" value="ACU76807"/>
        <property type="gene ID" value="Caci_7984"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7984"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_3_11"/>
    <dbReference type="OMA" id="VSMRQED"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="16490" checksum="C328B0A5AA6031CB" modified="2009-10-13" version="1">MDAVDRKILTELQNDGRLTVTELAARIQLSVSPCHRRLRDLERAGVIRGYRAVVDPAAVGLDFEAIVFATLRGSGGDTVTAFEEAVAAIPHVIQAQRLFGEPDYLLRVATTDLAAFQQLYDQRLARLPGVQRLTSTLVMKHVVSDRPLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH01</accession>
    <name>C7QH01_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate--cysteine ligase EgtA</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthase</fullName>
            <shortName evidence="2">GCS</shortName>
            <shortName evidence="2">Gamma-ECS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">egtA</name>
        <name evidence="3" type="ordered locus">Caci_8028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8028"/>
    <dbReference type="EnsemblBacteria" id="ACU76851">
        <property type="protein sequence ID" value="ACU76851"/>
        <property type="gene ID" value="Caci_8028"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8028"/>
    <dbReference type="eggNOG" id="COG3572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037109_0_0_11"/>
    <dbReference type="OMA" id="GLTFREW"/>
    <dbReference type="UniPathway" id="UPA01014"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02034">
        <property type="entry name" value="EgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017809">
        <property type="entry name" value="EgtA_Actinobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035434">
        <property type="entry name" value="GCL_bact_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011556">
        <property type="entry name" value="Glut_cys_lig_pln_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378">
        <property type="entry name" value="PTHR34378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378:SF1">
        <property type="entry name" value="PTHR34378:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="40275" checksum="F15574F8A389DB05" modified="2009-10-13" version="1">MECMTHLTVEGALEYISGICFKTGPPSRVGVELEWFPRDARHPEHLPDRSRVLRAFADAADLPLSGTLTMEPGGQWELSSAPADSVRELIAVTDRDLTLLRRSAAEAGLELVGMGREHGHPPSRLVDHPRYVAMEHFFDRDNGSGRVMMCSTASIQVNLDAGTEHDGPEDFRRRWRLAHRLSPVLTAVFCRSDRPAVWAAIDPGRTVAPPLDSPDPRSAYAQYALDAKLMCVQRADDGPWTAPAGLTFREWIKTGALEPGEDRAPTLEDLTYHLTTLFPPVRPRGHLELRVLDALPGDLWRVPTALVTALFHDAQAAEDAWAALELTPIRKAAAACFDAALSALERMDVPASLTAEVARYAEEDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHD4</accession>
    <name>C7QHD4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0118"/>
    <dbReference type="EnsemblBacteria" id="ACU69073">
        <property type="protein sequence ID" value="ACU69073"/>
        <property type="gene ID" value="Caci_0118"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0118"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_5_11"/>
    <dbReference type="OMA" id="WEFDVLT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21198" checksum="E1926D6CC72D3B0C" modified="2009-10-13" version="1">METPHTQGLDAATPADNGAPAPAAPAASDPQACRDEVDRLVEAWRHERPDLDVAPLEVLSRVSRLARHLDRARRTAFAEHDLEPWEFDVLSALRRAGAPYQLTPSKLLTQTLVTSGTMTNRIDRLAAKDLVKRLPDPGDRRGVLVQLSDTGRERVDGAFEGLLAQERELLGGLSAGDRTTLAALLRTLVLPFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHM8</accession>
    <name>C7QHM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family with acetyltransferase activity</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786346.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2134"/>
    <dbReference type="EnsemblBacteria" id="ACU71053">
        <property type="protein sequence ID" value="ACU71053"/>
        <property type="gene ID" value="Caci_2134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2134"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065219_0_0_11"/>
    <dbReference type="OMA" id="NEHIYDS"/>
    <dbReference type="OrthoDB" id="1823496at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="162"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="35530" checksum="3CC5391CD45C7D58" modified="2009-10-13" version="1">MVDLAPAVAAVRSFNRSYTKVIGVLEDGLLKSPYTLTEVRVLLEIAHAGPEGSTVVRIREDLGLDPGYLSRILARFDSEGMVVKGRAADDARRGTVQLTERGRGVFSGLDERSSEQVGEWLSRLGAGDRGRLVEAMGQIGGLLGFAENKASASQAPPSKADVVLRAPRPGDYGWVVERHGALYASERDFDETFEADVARIVADYAGSHDAEREAFWIAEVQGRRVGCVACVRRPTEDGVDTAQLRILLVDPSARGFGVGRRLVDECLEFARKVGYQRMMLFTVDGLSSAHRIYRARGFEIVRQEAVEMWGHHLVEQEWELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHS4</accession>
    <name>C7QHS4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MPAB_Lcp_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786392.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71099">
        <property type="protein sequence ID" value="ACU71099"/>
        <property type="gene ID" value="Caci_2180"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2180"/>
    <dbReference type="eggNOG" id="COG3662">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059206_0_1_11"/>
    <dbReference type="OMA" id="HGDFTSM"/>
    <dbReference type="OrthoDB" id="1395053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPAB_Lcp_cat" evidence="2">
        <location>
            <begin position="56"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="35057" checksum="7C4B132C9AEE0393" modified="2009-10-13" version="1">MTARLTAFSGPARGLKAYIRHELNTSVHGSGGLRLKERYAEPPGDPGLFGPGAVTWRVHSDAPGMLMGGFASLMLQALHPLAMAGVDQHSDFRTDPLTRLNRTAAYVLSTTFGSKDVAEAAVAHVRDRVHPHIKGTAPDGRTYSAEDPHLLTWVHVAEVRCFLAGYERFGAPPLTPAERDQYYREVAVPARMLGARDVPESAAEVAQYFHDIRPELQATEAAIEGIHFIRGFGANPRERAAVRVLMNGASALLPDWAREPLQLGRPDAVRLLIDRPLAQAAGRALRWALEPSEVVGTAYARMGLTPPPQHRDWRTAPGSSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHZ7</accession>
    <name>C7QHZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792771.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73042">
        <property type="protein sequence ID" value="ACU73042"/>
        <property type="gene ID" value="Caci_4178"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4178"/>
    <dbReference type="HOGENOM" id="CLU_2033859_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="126" mass="14222" checksum="4AE6912EEA4E5573" modified="2009-10-13" version="1">MGINHAHHDRHGTDQRAAVRSAEQAVSDAWIGQLLLAEYEAHVAVDICTRVREQLADRLRAAELSGDPPAIEETARRFANAEHACAVALDTYSESRDLLAEQLDDWLCATRMRFREAQDDRRVIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QID1</accession>
    <name>C7QID1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794737.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6154"/>
    <dbReference type="EnsemblBacteria" id="ACU75008">
        <property type="protein sequence ID" value="ACU75008"/>
        <property type="gene ID" value="Caci_6154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6154"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="ISAQNHY"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="33839" checksum="3DBBB21470BFE9E8" modified="2009-10-13" version="1">MRYRHLGNSGLLVSVVGLGCNNFGGRLDVAGTRRVVDAAIDAGITLLDTADMYGQSKSETFLGEVLQGRRDQVVLATKFGHQGFDMGYPPAAGAKGGRAYIRRAVEASLQRLRTDYIDLYQLHTPDPATPIAETIAALDDLVREGKVRYLGNSNFAGWQIAEAHYVAEQLNATPFISAQNHWSLLVRDAETEVVPAARHFGLGVLPYFPLANGLLTGKVRRETGIPSDARLAGRPQWVTEDRLDKVEALITWAEKNGRSLLDVGIAALAAQPGCASVISGAMSPEQVQANAAAGDWEPTAEQLAEIDAIVPAPAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIF9</accession>
    <name>C7QIF9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylacetate-coenzyme A ligase</fullName>
            <ecNumber evidence="1">6.2.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylacetyl-CoA ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-phenylacetate + ATP + CoA = AMP + diphosphate + phenylacetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:20956"/>
            <dbReference type="ChEBI" id="CHEBI:18401"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57390"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aromatic compound metabolism; phenylacetate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phenylacetyl-CoA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.30" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794765.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6182"/>
    <dbReference type="EnsemblBacteria" id="ACU75036">
        <property type="protein sequence ID" value="ACU75036"/>
        <property type="gene ID" value="Caci_6182"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6182"/>
    <dbReference type="eggNOG" id="COG1541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035301_1_1_11"/>
    <dbReference type="OMA" id="GVAPHFQ"/>
    <dbReference type="OrthoDB" id="839891at2"/>
    <dbReference type="UniPathway" id="UPA00930"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047475">
        <property type="term" value="F:phenylacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05913">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028154">
        <property type="entry name" value="AMP-dep_Lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011880">
        <property type="entry name" value="PA_CoA_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14535">
        <property type="entry name" value="AMP-binding_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006444">
        <property type="entry name" value="PaaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02155">
        <property type="entry name" value="PA_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="86"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C_2" evidence="3">
        <location>
            <begin position="340"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="47445" checksum="4F8ACC8FEE1046A0" modified="2009-10-13" version="1">MSSLPEIASRVLDDAERTSVGELRALQTERMAWSLNHAYANVPHYTAAFDAAGVHPRDFKELADLKHFPFTAKKDLRDNYPFGMFAVPREHVARIHASSGTTGKATVVGYTAADLENWASVGARSLRAAGVRPGDRVHVAYGYGLFTGGLGVHYGAEVLGCTVIPISGGQTARQVQLIQDFEPDVICVTPSYLLAIVDEMEKQGIDPASTSLRIAVLGAEPWTDAMRAEIEERLAVHAVDIYGLSEVMGPGVGNEDVAEKDGTYLWEDHFYPEIVDPETGEVLPDGAKGELVFTSLTKQAMPVVRYLTRDLTRLLPGLSRPMRRMERITGRSDDMMIVRGVNLFPSQIEEELLTVAGLAPHFVCVLTRPGRLDELCVRVEAREAEVDRGAAAGRLASGVKERFGVTITVDVLDPGGLERSQGKAQRILDLRGDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ4</accession>
    <name>C7QIQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796679.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8131"/>
    <dbReference type="EnsemblBacteria" id="ACU76954">
        <property type="protein sequence ID" value="ACU76954"/>
        <property type="gene ID" value="Caci_8131"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8131"/>
    <dbReference type="eggNOG" id="ENOG50345X6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_193873_0_0_11"/>
    <dbReference type="OMA" id="CSLFGFY"/>
    <dbReference type="OrthoDB" id="2062373at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="64" mass="6859" checksum="315C2F6EFCF2FF33" modified="2009-10-13" version="1">MVFSVSGVLLLGIITFILFRKDGLKVSHMIVCALLGFYLASTSIAPNIKQSGASIASFISNLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIW0</accession>
    <name>C7QIW0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796735.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8187"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77010">
        <property type="protein sequence ID" value="ACU77010"/>
        <property type="gene ID" value="Caci_8187"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8187"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_7_4_11"/>
    <dbReference type="OMA" id="IYTEYSM"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="25651" checksum="E810875D0753FE3C" modified="2009-10-13" version="1">MNADKRVLIIIPAWNEAGSIADVIAEVRGELPDYDVLVVNDGSTDDTERVALASGAKVVSLPYNLGVGGAMRLGYRYADENDYDIAVQLDADGQHDPRYVPKLIAGLGEARLVLGARFAGEGDYQVRGPRWWAMSLLSRVLSRMAKTRLDDTTSGFRACDREIIRLFAQWYPVEYLGDTVETLVRVIRLGYPVSQVPVAMRQRTAGTPSNSPIKAAVYLGRALITLLLAVNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ95</accession>
    <name>C7QJ95_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0284"/>
    <dbReference type="EnsemblBacteria" id="ACU69237">
        <property type="protein sequence ID" value="ACU69237"/>
        <property type="gene ID" value="Caci_0284"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0284"/>
    <dbReference type="HOGENOM" id="CLU_2841730_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008651">
        <property type="entry name" value="Uncharacterised_HicB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05534">
        <property type="entry name" value="HicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="65" mass="6906" checksum="7DCC9614943400FF" modified="2009-10-13" version="1">MVRINLRLPSNLKALVEDAAGAAGLSVNAWIVRAAAAGLANEDRRAGRAQRSDRIVGDSYSGWAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJA3</accession>
    <name>C7QJA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784540.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0292"/>
    <dbReference type="EnsemblBacteria" id="ACU69245">
        <property type="protein sequence ID" value="ACU69245"/>
        <property type="gene ID" value="Caci_0292"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0292"/>
    <dbReference type="eggNOG" id="COG1413">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090000_0_0_11"/>
    <dbReference type="OMA" id="TLTHQWL"/>
    <dbReference type="OrthoDB" id="1255025at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="29941" checksum="2A2C8C9EB594BC24" modified="2009-10-13" version="1">MAWFVHLTPEKNSARVRRSGLSPISRSRSDDPRPGLYCTPLLADYTLTYQWSREIKRWKSPRLAAVHFRIPDDTAVTVGYYGDAPKPVTAAQAVARFLSLSPEEMRGYEVFLPRGVTAKEIRRIKSLERPIGWRYRPNAHGHRPCACPACLDRGEYRISRIRDKSSYYDTSHLPPRQEVLEKLATTRDSAEIVTLLDQLRSRGQGDIFRVAHLADHPDPDVREALAYALCGFNKKAAAELLEKLRSDPLKDVREAAGADEDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM8</accession>
    <name>C7QJM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Peptidase M50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_2333</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786544.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2333"/>
    <dbReference type="EnsemblBacteria" id="ACU71251">
        <property type="protein sequence ID" value="ACU71251"/>
        <property type="gene ID" value="Caci_2333"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2333"/>
    <dbReference type="eggNOG" id="COG1994">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066211_0_0_11"/>
    <dbReference type="OMA" id="HEIMHGL"/>
    <dbReference type="OrthoDB" id="1401629at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU71251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30497" checksum="299AB3572EA50690" modified="2009-10-13" version="1">MARNNLRLLQPGEYRPDWSQAARGGGISPIFLALIAGFAASGFALYKGYGSDRAGVFIFVLCGWLISLCLHEFMHAAAAYWAGDHTVAGKGYLRLDPRVYGHPVLTFVLPLFFLLVGGLPLPGGAVAIESHRLRGKWKDSLVSAAGPAVNVVFSIVLLAVLDGFGPPWIFSPTSPDHAALWSALTFLAYIQIASAILNLLPIPGLDGYGIIEPFLSADWRRMAAQIAPYGILIVFVLLYALGPDKNFIANWAHDILEPRSPVNGEYFGYNLFKFWGSFNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJR1</accession>
    <name>C7QJR1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4285"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73149">
        <property type="protein sequence ID" value="ACU73149"/>
        <property type="gene ID" value="Caci_4285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4285"/>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048095_0_0_11"/>
    <dbReference type="OMA" id="MLVADSC"/>
    <dbReference type="OrthoDB" id="543482at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981041" evidence="2">
        <location>
            <begin position="43"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="3">
        <location>
            <begin position="369"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="48202" checksum="FDB78BAAB1BF2E83" modified="2009-10-13" version="1" precursor="true">MRSPRPAPPSRRRRAVVRTAVAAAAALVVALTAAVLTSPAQALGVGGTSSPVTGNATHFDGLGAPYGGCGVPQANLDSQDFIALNVFNTPGNYNQFTRPVPPAQASILGMFDNGLNCGRWVKVSIGDLCTGTNDGAPNQPFCRNGSWVADKYNGATLNMLVADSCADSNAWCRDDPYHIDLHTDSINRFQLNGSAVGDLLNHWNNRQVSWQFISAPGYSGDINIGFMQGAQVYWPAISVSHLANGIHGVQYLSASGTWVSAAMDSDMGQSYIIAPTATAGSSYQIRVTDASDNLINGGQVYSFSLPSSCGGSCSAAYTQVPYTTTPGSGPSSPSSSPSTTPSTSASSPSTPPSSPSSSGPSTPPSSPSSSAPASGCSVTSSVTGSWSSGYQLAFTVTNTGKVASSQWAVRFSFAGSQTIANSWNVTATQSGQAVTANSVSYNGSLAPGAATSWGMVVNGANQPLGGISCVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK20</accession>
    <name>C7QK20_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792987.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4394"/>
    <dbReference type="EnsemblBacteria" id="ACU73258">
        <property type="protein sequence ID" value="ACU73258"/>
        <property type="gene ID" value="Caci_4394"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4394"/>
    <dbReference type="eggNOG" id="ENOG50334P7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033809_1_0_11"/>
    <dbReference type="OMA" id="HFAKRAP"/>
    <dbReference type="OrthoDB" id="1701797at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="444" mass="47391" checksum="52F416F958AB5DA0" modified="2009-10-13" version="1">MSTDLSELTCPDCGAREQREAFCDSCGAALTRAKPAVVGAGAPAAFEESPSGESAGSAGNTGSTGSAESAAGVAAIPSARSGEAAAPASTAEHDSARAPGLHLVVDEADTVPLDEVARAEAERRELAEAAAERAEQAEKAERAERAERARALLVPVADQTEPPPGIVPVLPGKPDPIAPQRKNAEALEALDAGIECQWCATRNPPERHFCRRCGQRLAYAPVEARRPSWWRRVFFFWRNRPLPFAGQRPRLRRGPGQAIRPVVWAIVVVVVIVVVVQEYSPVSKNVRDHFAKPNEISNWTIGASHEDPNHKAKLLHDTYSDTWWGSGFSPQNTNGASVTVTFSQPANLLDLGITPGAGTAADTFGAQGSPETIEAELIPIPGKGAPIKKTFTLDDQPGFQKVQLRGDDIRQVVLTITSSYPPTAADPAKAVETAVTELEFYTRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK79</accession>
    <name>C7QK79_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794882.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6299"/>
    <dbReference type="EnsemblBacteria" id="ACU75153">
        <property type="protein sequence ID" value="ACU75153"/>
        <property type="gene ID" value="Caci_6299"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6299"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OMA" id="DSTHAYT"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="25899" checksum="8D0673D019C053E0" modified="2009-10-13" version="1" precursor="true">MNDFKGLTAIVTGGASGIGLATAKLLHSRGADVAVFDLKPDGLPEGIVGIEVDVTDDSRVAWAVEAVVERFGQLDVVVNNAGIPAIGDITGNSDAEWLGVLDVNVVGMVRVARHALPHLRRSPAAAIVNTCSIVAWAGMAQRVLYSASKGAVYALTLAMAADHVREGIRVNCVAPGTADTPWVDRQLNELPDPEAARAAMNAFQPAGRLVTADEVAGAIAYLASPLSGGTAGTVLAVDNGMHGLRLRPPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKC9</accession>
    <name>C7QKC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase domain protein FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6349"/>
    <dbReference type="EnsemblBacteria" id="ACU75203">
        <property type="protein sequence ID" value="ACU75203"/>
        <property type="gene ID" value="Caci_6349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6349"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059021_1_4_11"/>
    <dbReference type="OMA" id="THDVLIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="24"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="183" mass="19969" checksum="B0E0F7F836B71C8C" modified="2009-10-13" version="1">MAKAMAAPVPAGAASDPRELRRIFGRFATGITVVTAGGDEPRGMTANSFTSVSLDPPMILVCVLRDASMHETIKEREGFAVSVLSNRQERIARYFASRDRPRGPEEFDAVEHIRGPHTGAPVLPDALAWFECSLAAVYEGGDHSIFLGEIVTVGRGPDEDALLFYAGSYRRLEAPTDWRDHIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKD6</accession>
    <name>C7QKD6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional deaminase-reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794939.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6356"/>
    <dbReference type="EnsemblBacteria" id="ACU75210">
        <property type="protein sequence ID" value="ACU75210"/>
        <property type="gene ID" value="Caci_6356"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6356"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_1_3_11"/>
    <dbReference type="OMA" id="EMMEEAW"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19377" checksum="7ADF117C203FFA47" modified="2009-10-13" version="1">MRTLIVSSLVTADGIHGDPQLWAGEYSDEEAVEQWLGALKKSDAFLMGKNTYELFVQMWGTPEGPYLERLHEMPKYVYSSTLTSADWANTTIVSGDAVAAVRELKEQGDGDLMVYGYGRLSQALLEAGLVDRLDFTVNPVVFGSGTPLFRPGKRVNLRLDSVSRRGNGAVALSYVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKF7</accession>
    <name>C7QKF7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796781.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77056">
        <property type="protein sequence ID" value="ACU77056"/>
        <property type="gene ID" value="Caci_8233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8233"/>
    <dbReference type="HOGENOM" id="CLU_830780_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="34600" checksum="3DC68684E6C27573" modified="2009-10-13" version="1">MTYRSVEGYLDDLAWRLRVGIRGRRRIVSEVAAHLADAIAEEEAAGHTPQAAARRATARFGAPEEVAAEFNRDCALHSARVAAWALVVGVVAAVGAAGLANQGGAPVVPWPNQAVYYAGPVLLGQVAAMCAGTAFLIAVIAPRVLGRAPGTLATAVRAQAVAVLALLPIGVVAAGNIARSSWTLGAVSALAALAVPVAMVLSVRALLRVGTVSGGSSTLDVIADCSEVLAARWMWSARLFELVTRTWATAAARMPHLMSWLEMRRHPWRSAVTISVAAGVALKAPDLLKGDVDLPAAAIEAVAAFVGYCLFSALLGLRAAQPVGARTRSRAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKK2</accession>
    <name>C7QKK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8278"/>
    <dbReference type="EnsemblBacteria" id="ACU77101">
        <property type="protein sequence ID" value="ACU77101"/>
        <property type="gene ID" value="Caci_8278"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8278"/>
    <dbReference type="HOGENOM" id="CLU_095244_2_0_11"/>
    <dbReference type="OMA" id="WNATHAQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025339">
        <property type="entry name" value="DUF4245"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14030">
        <property type="entry name" value="DUF4245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981074" evidence="1">
        <location>
            <begin position="30"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="20480" checksum="0DF0B23C9B724C8D" modified="2009-10-13" version="1" precursor="true">MARVSPLKKSLRDMLLSMAVISLPLVAIVEWFPHDSKKPEDAVQTVDYTIPLAQARRDPDLPFQAMAPTSLPPGWRATSVHADLDPSAQLRWELGFLTSDDQYVALDQTAGGKGVDGILSLQAPDATQVSGAGGTVTAGGYQWQVYVTPDGSRHALVRTTAPEGSAAATTRGKVGVVVSGSGALTELETLAGSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD1</accession>
    <name>C7PVD1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="9" type="ordered locus">Caci_0334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784582.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0334"/>
    <dbReference type="EnsemblBacteria" id="ACU69287">
        <property type="protein sequence ID" value="ACU69287"/>
        <property type="gene ID" value="Caci_0334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0334"/>
    <dbReference type="eggNOG" id="COG0359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078938_5_1_11"/>
    <dbReference type="OMA" id="MKIILTH"/>
    <dbReference type="OrthoDB" id="1959318at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16180" checksum="01982534C4F26067" modified="2009-10-13" version="1">MATTKLILTHEVGGLGEPGDVVEVKGGYARNYLVPRGYAIAWTRGGEKQIELIRKARKVRTVRDLAHATELKGELEGLRVRLATRAGESGRLFGGVTVADVADAVKRAGGPDVDKRRIEIGNPIKTVGAHTVSVRLHPEVQAKVEITVVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVE0</accession>
    <name>C7PVE0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_0343</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0343"/>
    <dbReference type="EnsemblBacteria" id="ACU69296">
        <property type="protein sequence ID" value="ACU69296"/>
        <property type="gene ID" value="Caci_0343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0343"/>
    <dbReference type="eggNOG" id="COG5542">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036370_2_0_11"/>
    <dbReference type="OMA" id="WKHAQER"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:glycolipid mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="PTHR12468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU69296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="38907" checksum="5ABC3032FE9BE339" modified="2009-10-13" version="1">MAVLTWISAWVFVAGPTKQGSLLARWDRWDEGIFTSVAQHWYFAAGTDPRHVAFFPGFPIAMWLAHLVVWNWIAAGLVVSAAAGAIATMALGRLARDEVDASNADADAGQAAANATLFFVLAPAAVFLAAGYSESLFAAFAFSAWVAARRDRWWLAGLLAAGASTVRVNGLFLAAAIALEFILAGRERRQWRQAPLLVIPALPVIAYVVYLHHETGDWLAWQHAQAAGWFRTFQSPESAWNQTWRAAFGGTQAGHTAWVFQLELIAVVIGLALTALLLLKRRWPEALYVALSLLALGTTTWFMSVPRAMLLWWPLWTMLGAWAARRPMVRTLYVCCVAPVMVGVALLFLSGQWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA1</accession>
    <name>C7PWA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 2-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793078.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4486"/>
    <dbReference type="EnsemblBacteria" id="ACU73349">
        <property type="protein sequence ID" value="ACU73349"/>
        <property type="gene ID" value="Caci_4486"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4486"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_0_2_11"/>
    <dbReference type="OMA" id="QVHAVNI"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050112">
        <property type="term" value="F:inositol 2-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="130"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="35438" checksum="295213D31EBBF780" modified="2009-10-13" version="1">MTLLGLVGVGRIGAFHAKTLHGLPDVEVVVADVQAGRAEELAASLGVRWAPDIGSLLRTDLDALVVATSTGSHAELIERGVAAGIPVFCEKPVAENSAKTLEVISSVDKFGGRVQIGFQRRFDAGYVAVREEVQTGALGRVHTLRAQTSDPVPPPAKYIATSGGIFRDCSVHDFDAIRWVTGREVVSVFASGSARGEAFFAEFGDADTAAAVLRMDDDALASVTATRYHGAGYAVTLDVAGTQGSVGAGYDDGLPLRPVGVPDAGSDGAFPKGPAYAGFMDRFQEAYAGELQAFVQFAQGRIENPCPVGEALEALYVAEACDVSRAQNRPVTIAEVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWP0</accession>
    <name>C7PWP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795049.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6469"/>
    <dbReference type="ESTHER" id="catad-c7pwp0">
        <property type="family name" value="Haloalkane_dehalogenase-HLD1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75320">
        <property type="protein sequence ID" value="ACU75320"/>
        <property type="gene ID" value="Caci_6469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6469"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_3_11"/>
    <dbReference type="OMA" id="GAVAWCE"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="287" mass="31393" checksum="5FCAE617952D070D" modified="2009-10-13" version="1">MPLLPVLDSAIHYRESGDPNGLPFVFLHGNPTSSHLWRDVLPRVAAPGRRLLAPDLIGMGASGKPDLAYSFDDHARYLDAWFDALGVDEAVLVGHDWGGALAFDRAARLPERVRGLAFAETIVKPLVGDEFPVAGRELFEQLRMPGVGEEMVLEKSLFIEGVQGTLATPLDPADLDVYRRPFPTPESRRPILAWTRMMPLDGEPADVVARVERYDRWLATSPEVPKLLVAFEPGPGAMTDAGAVAWCEANIAGLEVSRHGVAGHHCPEDRPEEMAAAINAWARRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWU6</accession>
    <name>C7PWU6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_8380</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796928.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8380"/>
    <dbReference type="EnsemblBacteria" id="ACU77203">
        <property type="protein sequence ID" value="ACU77203"/>
        <property type="gene ID" value="Caci_8380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8380"/>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_0_0_11"/>
    <dbReference type="OMA" id="DMIMLKD"/>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="37"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="127"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU77203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="31398" checksum="CC7EC2F12C1A835C" modified="2009-10-13" version="1">MSSLSPDVAKALTDGGLDPEYVASVIMMALDEDLADGPDVTTEATVSADATDTADFAARAVGVAAGVPVAAAVFDLVSQGTAKIRQAVKDGDRVEPGTVLLTVTGATRDLLTGERTALNLLCHLSGVATQTRLWVDAVEGTGTKIRDTRKTTPGLRALEKYAVRCGGGENHRMSLSDAGLVKDNHVVAAGGVVEAFEAVRKAHPGLPIEVEIDSLEQLPGVLAAGAELILLDNFTPERMRAAVQVTGRNELYGRTRLEASGGLTLDLARAVAETGVDYISVGALTHSAPILDVGSDFREEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXC1</accession>
    <name>C7PXC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxamine 5'-phosphate oxidase-related FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784767.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0529"/>
    <dbReference type="EnsemblBacteria" id="ACU69472">
        <property type="protein sequence ID" value="ACU69472"/>
        <property type="gene ID" value="Caci_0529"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0529"/>
    <dbReference type="eggNOG" id="COG3576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054794_1_1_11"/>
    <dbReference type="OMA" id="SCGWSVP"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="2">
        <location>
            <begin position="10"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="23549" checksum="1B3681C8BD6B6E55" modified="2009-10-13" version="1">MSKVYEKINHQMAGWIHRQPIFFVASAPLAASGRVNVSPKGLMGTLVVLDPHSIAYLDYTGTGAETIAHLRENGRITVMFCAFEGRPKIVRLYGRGRYTVPGEPEFDKLRELFEKTTTAGQRSIIIVDIDRITDSCGWSVPLMDYREDRAVLDLHNERRDDAYFEKYWQTTNADSIDGLPALRSEPEPEPGLAPEPESEYLVVSASGSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL0</accession>
    <name>C7PXL0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal peptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786756.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2545"/>
    <dbReference type="EnsemblBacteria" id="ACU71463">
        <property type="protein sequence ID" value="ACU71463"/>
        <property type="gene ID" value="Caci_2545"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2545"/>
    <dbReference type="eggNOG" id="COG2261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160040_1_0_11"/>
    <dbReference type="OMA" id="WLWAIIV"/>
    <dbReference type="OrthoDB" id="2084822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9649" checksum="A9F999F23BAED759" modified="2009-10-13" version="1" precursor="true">MFQLLWILIVGLILGALARLILSGKQNIPIWLTMIAGVGGAWLGNAVSGWIHVRHTGGVDWIRHALQLGFAVALVALASAMWAGRSSARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYF2</accession>
    <name>C7PYF2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795171.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6596"/>
    <dbReference type="EnsemblBacteria" id="ACU75442">
        <property type="protein sequence ID" value="ACU75442"/>
        <property type="gene ID" value="Caci_6596"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6596"/>
    <dbReference type="eggNOG" id="COG0599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148076_0_0_11"/>
    <dbReference type="OMA" id="ISYLAHI"/>
    <dbReference type="OrthoDB" id="1874165at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11363" checksum="735B6071B8BE8533" modified="2009-10-13" version="1">MAMTSPTPVLDTIAAMTIDSLERCSMDPRTLVLTRLAALCAMDAPPISYLAHVGPAQEANVTLEQVQDLLVAIAPVVGTARVMSAAGHITEALGFAITVAEDENGAMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYG0</accession>
    <name>C7PYG0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795179.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6604"/>
    <dbReference type="EnsemblBacteria" id="ACU75450">
        <property type="protein sequence ID" value="ACU75450"/>
        <property type="gene ID" value="Caci_6604"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6604"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="ISNMARY"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980461" evidence="7">
        <location>
            <begin position="28"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="19"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="515" mass="50582" checksum="1F3D5A842B1FD709" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYS5</accession>
    <name>C7PYS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797122.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8578"/>
    <dbReference type="EnsemblBacteria" id="ACU77397">
        <property type="protein sequence ID" value="ACU77397"/>
        <property type="gene ID" value="Caci_8578"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8578"/>
    <dbReference type="eggNOG" id="ENOG502Z84P">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060481_0_0_11"/>
    <dbReference type="OMA" id="ACEIRVS"/>
    <dbReference type="OrthoDB" id="1355200at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024414">
        <property type="entry name" value="Uncharacterised_PrgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12666">
        <property type="entry name" value="PrgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="293" mass="30555" checksum="090CFCE8C9F41EBF" modified="2009-10-13" version="1">MSDGPAGYSAVRIPADVSRPDRVLGPATARQVAIIGSTATGLWCAWLGVRAWVSPFAFLIPAVFFLVIVGVAVSTERDGLAIDRLLAAALRQMRTPRRRVMAPEGVAPPPPFLSEALNKPPCLPAPLSLPIADLDHTGVIDLGTDGTALVAAAGTVNFGLRTADEQDLLLGGFARWLNSLSGPTQITSTNAPADVSGFVGILRDRAANLPHPALGHSAQEHAEFLDGLAATRVLLTRSIHLALREPGKAAAQRVARRAEDAVSHLAACEIRVSPLGHDAASADLRALLDPSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ06</accession>
    <name>C7PZ06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0626</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0626"/>
    <dbReference type="EnsemblBacteria" id="ACU69562">
        <property type="protein sequence ID" value="ACU69562"/>
        <property type="gene ID" value="Caci_0626"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0626"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="34931" checksum="B442C888AC12BAB1" modified="2009-10-13" version="1">MTSATIGVRRGRVKGSPLARRRRRVFGPFLAPALILYTVLFMVPTAYSFYASFTSWDGFSNPRWKGTLNYDHLTHDPAFKDAFFNTLKLLFGCGIFLFVLSFAFMLMLREMKGRRFIQGFIFLPHIVSGVALAAFWDFLLNHDGMLNKGLHSFGLGPVDWLKPQWQFDAILVAIVWINTGYYVTILMAGVDRIPPYYYEEAKLAGTNSWQRFRHITLPMSWDVIGTAAVLWTIGTVKIFEFILAFSGSQGNLPSTNQWTSAMYVYGETIGGTSPIYDFGRACAGAVVTLVAVVVVVVVLRRVTSRDRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ53</accession>
    <name>C7PZ53_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neutral ceramidase</fullName>
            <ecNumber evidence="3">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the neutral ceramidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0673"/>
    <dbReference type="EnsemblBacteria" id="ACU69609">
        <property type="protein sequence ID" value="ACU69609"/>
        <property type="gene ID" value="Caci_0673"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0673"/>
    <dbReference type="eggNOG" id="COG3356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011300_2_0_11"/>
    <dbReference type="OMA" id="VWHRTNT"/>
    <dbReference type="OrthoDB" id="704008at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102121">
        <property type="term" value="F:ceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="PTHR12670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="domain" description="Ceramidase_alk" evidence="5">
        <location>
            <begin position="3"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Ceramidse_alk_C" evidence="6">
        <location>
            <begin position="486"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="643" mass="71035" checksum="96E4DE2AA0318FED" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZZ2</accession>
    <name>C7PZZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795214.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6639"/>
    <dbReference type="EnsemblBacteria" id="ACU75485">
        <property type="protein sequence ID" value="ACU75485"/>
        <property type="gene ID" value="Caci_6639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6639"/>
    <dbReference type="HOGENOM" id="CLU_142819_4_0_11"/>
    <dbReference type="OMA" id="AGHEKYE"/>
    <dbReference type="OrthoDB" id="2042592at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="11490" checksum="3FFEF09EA9BD7D35" modified="2009-10-13" version="1" precursor="true">MKRALTFATGLAVGYVAGTRAGHEKYELIKEKAHEVSEQPAVVDLRENLKGTVETASKAVTAKVADATSELTKKLHGSAHEEAASTPVKPAPAAPGEYPAAPTGIVPGSGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q018</accession>
    <name>C7Q018_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795240.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6665"/>
    <dbReference type="EnsemblBacteria" id="ACU75511">
        <property type="protein sequence ID" value="ACU75511"/>
        <property type="gene ID" value="Caci_6665"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6665"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="OMA" id="HVTVEEC"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="35635" checksum="874EC1282C5FDC3F" modified="2009-10-13" version="1">MTVVPHAVTAGREMVEAAMRAAVERLDPRMRRVAAYHFGWVEADGSAPRGPSGGKALRPAMALLSGRAAGADMARVVPAAVAVEFVHAFSLLHDDVMDNDRMRRHRPAAWTVFGVPAAILAGDALLALAEEVLLDRGTTGAHRAARHIAATTRKLIAGQALDLGFETRTDVSLDECTVMSMDKTAALFACSCSIGAVLAEAPNRLALALSGFGEDLGLAFQLVDDLLGIWGQPEVTGKPVLNDLRSRKKSLPVTAALGAGTPASTRLALLYSQPDPLTEPQLVEAAALIEEAGGRAWAESAADARIAAAEARLAEADIPGDVREEFLAVARFVTHRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q050</accession>
    <name>C7Q050_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795272.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6697"/>
    <dbReference type="EnsemblBacteria" id="ACU75543">
        <property type="protein sequence ID" value="ACU75543"/>
        <property type="gene ID" value="Caci_6697"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6697"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602299_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="454" mass="49220" checksum="B5826DE187BBCDC5" modified="2009-10-13" version="1">MEPGREHIDDYDQAEAAARVAEAQRLIADYQDTFKGTYSDLLTAFSQEMPDPMLQRHLLPPPALRARPTIDDYDHDLERLGHPAHDAFGHLRDLVLIGLRVGTISVEDLYSRVRPALVALTVLLDAGTGDAASALARRIRHGAGRGVADWTEAVVTVDAWPGSIRSLLKQQPQPGDDIPVHALLGLDEHLWRGANILLALAPPETLPHIAADAAPMGATGAIVGEPHAVRNARALVRIAGHAPLSRPVVDYALRPQTSARVRMALAGNPLTPNAVLVRLLTYAGREPGVAAAISLHECTSPAVRLAAYREVRDPAVREQAREALQRDAEVVRQVQLIASLTAKDVPLMHVLIRDADPELPIAARLFAYAHVARMSGIEVVWTLEMERAGALEAMHPAVRASMESGSVVPLLEAAVADPYRGVDQDAVTSVAMLRREEALDRPFPWQEAVGNQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q061</accession>
    <name>C7Q061_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FHA domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU75554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Caci_6708"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="89"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="7">
        <location>
            <begin position="631"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="7">
        <location>
            <begin position="967"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1425"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="649"/>
            <end position="656"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="983"/>
            <end position="990"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1447" mass="153217" checksum="FC993A754ED5DC8A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q062</accession>
    <name>C7Q062_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6709</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6709"/>
    <dbReference type="EnsemblBacteria" id="ACU75555">
        <property type="protein sequence ID" value="ACU75555"/>
        <property type="gene ID" value="Caci_6709"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6709"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="TSAREWG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
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    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
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    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="61"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="406"/>
        </location>
    </feature>
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            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="46389" checksum="5F886F701CBC46FD" modified="2009-10-13" version="1">MHDAAKPLASIPPLVLDIALAAAVTWLAVAASVRPHALHGSRHIDGIAITLVIAMGAALILRRRFPLAVLGVCAALVAGYEAHGYRMGLAQIGLLLAMFTVGALRARPWAALAAGITYAELLYDHSHTWSGSHVWFYLGTALWVAAVAIIADGARRLTESRELLAAYKEQVQRKHRDREQRAVLLERIRIARELHDVTAHHLSVIAVQAGVARFVIDKEPETADQALRAISEVGSEGLAELRRLISLLRPEDDEGARAHTSDPPAPGVAQLPVLIERVGLSGTPSRYTVAGHKRTLPAGIELCVYRVVQESLTNVLKHAPGSSVEVRLEYEPETIRVTITDTGTHPVPPRKSGIPAAAITQATRHSGSGVGLTGMRERAALYGGELSAGRTTNGGFEVALALPVVAEPAEAEEAETESEGGDGKIAAPAEAAKVGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q066</accession>
    <name>C7Q066_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795288.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6713"/>
    <dbReference type="EnsemblBacteria" id="ACU75559">
        <property type="protein sequence ID" value="ACU75559"/>
        <property type="gene ID" value="Caci_6713"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6713"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OMA" id="AEGTTEC"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36179" checksum="F3190E7E68865E20" modified="2009-10-13" version="1">MTKKTVGISDVAREAGVSVGTVSNSFNRPDSVAPETRARILAVVERLGYVRSESARQLRTGTSRIVALLVLDLANPFFVEVANGAERAARAAGLGVMVCTSAQSPSEEAEYVGLFTEQQVRGVLVIPADPTGRSLEPLRRQGIPYVVVDRLVEDAEVCSVSVDDVAGGRLAVEHLLAQGHRRVAYISGPAHLQQIRDRRTGALHAIAAAGLPPHTLHELPTAHMTIAAGRDAAARLLGLADRPTAVFCANDLLALGLEQALYSAGVKVPEEVAIVGYDDIEFASAVAVPLTSVRQPAAEMGRLAAQMLLAEAAGDDGIDHEHRSVVLQPELVVRTSSLHRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0R9</accession>
    <name>C7Q0R9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0762"/>
    <dbReference type="EnsemblBacteria" id="ACU69697">
        <property type="protein sequence ID" value="ACU69697"/>
        <property type="gene ID" value="Caci_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0762"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_8_11"/>
    <dbReference type="OMA" id="HAGDIEN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="229"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="46029" checksum="921D6E6BBAD652D7" modified="2009-10-13" version="1">MWSERSAEGPSTAAEEGMAGAAETAGRSSVFEEPPLLMAAPRVGQPGRFKWLFAAVWLFYLVDPVTKAVHSDHSSAFKLLVYSLVAVFVVLYGWLAFSVYPRSGPIGAVSDSPPVVLPILVAMAVVAFVTSVAVYPELAGMWVYVGAGAGLGLSMEDKTAYRGVMAALALMTVCVLSSGALRSISTWLILAFPIFFAGMSTLGIRQMALLIGQLREARTQVAHLATNEERLRLARDLHDLTGHSLATITLKAELAQRMLAKARDAAPEGPTPRLDAALKEVQEIEQVSRQTLTDIRQAVSGYRRATLAVEVASAHAALDAAGIKLDAAPEVAAATGEFDPQSEAALAWSLREAVTNAIRHSGAARVEITLLPIGEEMVLTVRNDGYGLAATVGGTDECGGHGLTGLRERLDAVGGRLSVGGNDGDFRLVAAVPVVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0W1</accession>
    <name>C7Q0W1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="6 10">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_0804</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase</text>
            <dbReference type="Rhea" id="RHEA:36431"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:142361"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="6 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785034.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0804"/>
    <dbReference type="EnsemblBacteria" id="ACU69739">
        <property type="protein sequence ID" value="ACU69739"/>
        <property type="gene ID" value="Caci_0804"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0804"/>
    <dbReference type="eggNOG" id="COG0005">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054456_1_1_11"/>
    <dbReference type="OMA" id="EGVYAQF"/>
    <dbReference type="OrthoDB" id="1364220at2"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011269">
        <property type="entry name" value="PUNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01698">
        <property type="entry name" value="PUNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="12">
        <location>
            <begin position="31"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="11">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="27758" checksum="644FB09EF3A429B2" modified="2009-10-13" version="1">MTNSSDAFQDPYALAESAAGRLSELTGRHDVAVVMGSGWAEAADALGTLDWESPVDALPGFAASTVVGHAGKVASVTVGGNKVLVFLGRTHLYEGRGVASVVHGVRTAVANGVKTVVLTNGCGGLRADMHAGQPVLISDHLNLQSESPIVGARFVDLTDLYSERLRVLARTVDPSLAEGVYLALRGPHFETPAEIRMFRGWGADLVGMSTALEAIAAREAGAEVMGISLVTNLAAGMTGEPLSHTEVMETGAASAASLGTLLQGIVEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q125</accession>
    <name>C7Q125_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_2787</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2787"/>
    <dbReference type="EnsemblBacteria" id="ACU71700">
        <property type="protein sequence ID" value="ACU71700"/>
        <property type="gene ID" value="Caci_2787"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2787"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="OMA" id="MTLPSAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="80"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="399"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="433"/>
            <end position="440"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU71700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="653" mass="69741" checksum="7CA4AF0FB1F3CC04" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1F4</accession>
    <name>C7Q1F4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4822"/>
    <dbReference type="EnsemblBacteria" id="ACU73683">
        <property type="protein sequence ID" value="ACU73683"/>
        <property type="gene ID" value="Caci_4822"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4822"/>
    <dbReference type="eggNOG" id="ENOG5032V2R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070582_0_0_11"/>
    <dbReference type="OMA" id="YLAWFGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021246">
        <property type="entry name" value="DUF2797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10977">
        <property type="entry name" value="DUF2797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="35387" checksum="D444760BDA193928" modified="2009-10-13" version="1">MALGQHASVTMVGVEANPNSVSVPAPSPAPDRLCIGLSWFEEKPALTSVEGGDLRLKALSPGARLALSWSGRRRCIGWTAPGTGRTPCADNAEIDGAATLAQCPACQNRDHGLAIARDRITDDGRSYQLYLAWFAPGMLKVGITGVQRGVARLLEQGAIGYTVIATGTLPAARRAEITVSASGLAKERYRSRAKVEAWWGLPETDGLRSALTEGRAKALRMLADHTLEAFPDGPLVDNTAFFGLGDGAPATYREVEALDDSGSLAGEVRAVIGKHVFVDGDADVGVGVSTPLLLNTQLLAGRHTVPTPDATAGANAVGVRTVERRRPLLYDTPTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Q5</accession>
    <name>C7Q1Q5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6761"/>
    <dbReference type="EnsemblBacteria" id="ACU75606">
        <property type="protein sequence ID" value="ACU75606"/>
        <property type="gene ID" value="Caci_6761"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6761"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_955433_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="28631" checksum="14F6A7747B3476B4" modified="2009-10-13" version="1">MSEGFAGSGGGAGDGDGGDGWGSGDATQLYAAMAQATADIGGVRVDPARMLRARRRHRLSEGGVVAGVLSVALVAATVAMYGGGGGTARVPGGTGSGVASPTVSAATAVTAVTAAPSKAVADVVVPTGVSVYDSAAGTEGGQSVHKLLSGTGAWVTNQYCQKVATSDGRPKGTGVIFDLGTPTPIAAATVDIGVPGAELEMWAADPSLHTPPAVRPGQPPAGFTKVATTDAATATTVLTPAQPVTTRYVMVWFGGALPAVPNPDISIQCAHADGDGNRYGDSISAVRFSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2E4</accession>
    <name>C7Q2E4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-translocating NADH-quinone oxidoreductase, chain M</fullName>
            <ecNumber evidence="7">1.6.5.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Membrane</location>
            <topology evidence="1 3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 4 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.11" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785081.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0853"/>
    <dbReference type="EnsemblBacteria" id="ACU69786">
        <property type="protein sequence ID" value="ACU69786"/>
        <property type="gene ID" value="Caci_0853"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0853"/>
    <dbReference type="eggNOG" id="COG1008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007100_4_4_11"/>
    <dbReference type="OMA" id="GHMGFVL"/>
    <dbReference type="OrthoDB" id="535707at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000260">
        <property type="entry name" value="NADH4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010227">
        <property type="entry name" value="NADH_Q_OxRdtase_chainM/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43507">
        <property type="entry name" value="PTHR43507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01059">
        <property type="entry name" value="Oxidored_q5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01972">
        <property type="entry name" value="NDH_I_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_q5_N" evidence="6">
        <location>
            <begin position="71"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="5">
        <location>
            <begin position="132"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="504" mass="52992" checksum="04290023C79C7DEB" modified="2009-10-13" version="1" precursor="true">MNALLLAMLLVPVAGIAVLYLLPSAVAERSATRVGFYAGGAVLVLAAALACVFKYSKTGYQGTVDWNWISALHIRFHLGVDGISLPLILLTALLSALCFFYSIRHMPDGGSQRSYTALLLLLEIGMLGTFMAADLILFFVFFEIVLLPMWALIAYWGSENAKAAANKFILYTLLGSAVMVVGFLVVFAYADSFDMAWLTAHARGDIPKGAALTAFALIALGFAVKTPMFPLHTWLPDAHTAAPTTGSVLLAGVLLKMGTYGFVRIAVPILPQAAPTYAPALAAFGVVGVIYGSLACLSIARKPDGDLKRLIAYSSIGHMGFVLLGIGSLTTVGMNAALFASVAHGLITGLLFFLVGGLKVRVHSAKLDDIGRALYRRAPKYGVLIAFAAMASLGLPGLAGFWGEVLALFSATKPGIGLTQSSYIAMAAVAALGLVLTATYLLAVVRRVCMGPAATPSEEPVTELTAVETATWTPLVLLTLLAGLWPALLLGITNPAVRVLMKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2F3</accession>
    <name>C7Q2F3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0862</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785090.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0862"/>
    <dbReference type="EnsemblBacteria" id="ACU69795">
        <property type="protein sequence ID" value="ACU69795"/>
        <property type="gene ID" value="Caci_0862"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0862"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512773_0_0_11"/>
    <dbReference type="OMA" id="WWQECAG"/>
    <dbReference type="OrthoDB" id="1705869at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="24"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="5">
        <location>
            <begin position="448"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="341"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="580" mass="59617" checksum="122D0B4AD2D60507" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2L2</accession>
    <name>C7Q2L2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ordered locus">Caci_0922</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785149.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0922"/>
    <dbReference type="EnsemblBacteria" id="ACU69854">
        <property type="protein sequence ID" value="ACU69854"/>
        <property type="gene ID" value="Caci_0922"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0922"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_11"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="17467" checksum="B4EB7E762CDF3DEB" modified="2009-10-13" version="1">MPRKGPAPKHPVVIDPVYNSPLVTSLVNKVLLDGKRSTAERIVYGALEGCREKTGTDPVITLKRALDNVKPTLEVKSRRVGGATYQVPIEVRAGRSTTLALRWLVGYSRQRREKTMTERLMNELLDASNGLGASVKRREDTHKMADANKAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S7</accession>
    <name>C7Q3S7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Daunorubicin resistance ABC transporter ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8872</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8872"/>
    <dbReference type="EnsemblBacteria" id="ACU77685">
        <property type="protein sequence ID" value="ACU77685"/>
        <property type="gene ID" value="Caci_8872"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8872"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="HRMNEVE"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043215">
        <property type="term" value="P:daunorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900753">
        <property type="term" value="P:doxorubicin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005894">
        <property type="entry name" value="DrrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01188">
        <property type="entry name" value="drrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="20"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="33456" checksum="0F08F26E5B449F0C" modified="2009-10-13" version="1">MAVMTTTARTTAATSATLAISVTGLRKSFGEKTVLAGVDLTVPAGTVFALLGPNGAGKTTAVRILSSLIAPDGGQISVAGHDLAEAPEAVRSVIGVTGQFSAVDNLLTARENLILMADLYRLGRRAGRVRAAGLLERFGLTDAADKPLSTYSGGMRRRLDLAMTLVGDPQVIFLDEPTTGLDPRSRRELWAIVRELVADGVTILLTTQYLEEADQLADRIAVLDGGRIIAEGTAAELKRLIPGGHITLRFADAAKLSAAADVLGADSVDEDALTLQVAGDGGFDSLRTVLDLLTSAGLPAEELSVHTPDLDDVFLALTADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Y5</accession>
    <name>C7Q3Y5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797467.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77743">
        <property type="protein sequence ID" value="ACU77743"/>
        <property type="gene ID" value="Caci_8930"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8930"/>
    <dbReference type="HOGENOM" id="CLU_1440364_0_0_11"/>
    <dbReference type="OrthoDB" id="2135844at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21531" checksum="3158C4B2E415C03F" modified="2009-10-13" version="1" precursor="true">MSMPTWLATVLIAAGTSVVARMVPDLTVVSRLDARKARVKAVHDARDRFSNCAITMLTLCGALVAWDIPDDVSDVVRARLEGESERWRGLIDETTVWLIDNSAFYALSWPRNLRVIAGRYATETRGVWLSERTEADKVRLLGDLTAHIQSIYFIRLWRVMARAEALRNVQNAFDALNSPPVPMPLPVVEESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4I8</accession>
    <name>C7Q4I8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage-related protein predicted endonuclease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3048</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3048"/>
    <dbReference type="EnsemblBacteria" id="ACU71957">
        <property type="protein sequence ID" value="ACU71957"/>
        <property type="gene ID" value="Caci_3048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3048"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065987_0_0_11"/>
    <dbReference type="OMA" id="IADRRPH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="2">
        <location>
            <begin position="15"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="312" mass="34623" checksum="BB15574B8F029DD1" modified="2009-10-13" version="1">MSPELIGFFKPGSPDWHAARTTGVGGSEVAALLKISKWESRFSLWHRKQGLIGPKASNSEMEAGRRLEPAICRKFADEHPEFRVVQAGTYRHRERTYQLANPDRLIFDACTCGSAKCDHPLPPQPVGILEAKFALYPDEWGEEGTDQIPPYYQVQDRWYLDVFGLSPCHTEVFIGSTGEFREYIIEADAAQAGVMRQAAREFMDSIRDQVRPDIDEHGETYTAVRDLHPDIDDEVFEVPPHIAIPYMDAVDAARAANAVKSQAAAVLLDAMGRARRAYFLGEQIAMRVPGRGGSAPSLRAEPQTPIEKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4W2</accession>
    <name>C7Q4W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793639.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73910">
        <property type="protein sequence ID" value="ACU73910"/>
        <property type="gene ID" value="Caci_5050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5050"/>
    <dbReference type="HOGENOM" id="CLU_539361_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980594" evidence="2">
        <location>
            <begin position="25"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="505" mass="50423" checksum="05307B04ABD53D45" modified="2009-10-13" version="1" precursor="true">MQIALSRVAAVAAVTALGVGGCSGSGSTGSGSGSSGLNGGSKATGKTGDAGAPAGASLSGKVPSGFANATTWSTQVAWGDRGVGKAALDLHGHGVSNWVVAEQQGSFGVVRTVGTSVVVPSFASGGAAGPVAATLKFLDAKTGKPIAEKKLPSGTFLGLDADVVAGKPVAVVRYLPAQDDASPVVVVFDASGAQVWSTEGKQVAGTSPWSGGLQDGENGEGLLVGGYALRLNIGKDTSDHTDATYDVVDTTGKSVLHVPLYADKWDMNSVNIVQGYAVVSYDDSLSLPDTSTAKEHFTVYDLSAAGKKVAEVAEKDSGGVSNAVALAASGGKILLTWLGSGTGAMPPTLMTVLDTATGQATPPAPLPGAVTDFGTLIDPATKNVLFFDRADPPTDSSAMVSLSQGTVLWTQHDQHSSLIPLSMHNGVVYGIEAAELGSSDGNQLAVKEADGSPVDTDYELSPLDFTADGAPLFAEASDGSESDSGSSDSSGSGTYTVTVGVGHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q580</accession>
    <name>C7Q580_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795577.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75849">
        <property type="protein sequence ID" value="ACU75849"/>
        <property type="gene ID" value="Caci_7019"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7019"/>
    <dbReference type="HOGENOM" id="CLU_1522497_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="18619" checksum="7834590B2957E92D" modified="2009-10-13" version="1">MVLLSGQQWPAFAVGSDGLLDYGATQQDELPLDTVGVAAADRGTLTDNDAGQPDSAFLNDDVTLAELKWIQNENDEVSPADVAMTISTELNPAPTYLPLKNGGELTLYGTRFSLRVSQSGRTFSVDDQGWAKIAGATSFQGGFTIEAVWMVAAIDPPDKTGKIEKIASNGGPVSMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5E3</accession>
    <name>C7Q5E3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7082</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7082"/>
    <dbReference type="EnsemblBacteria" id="ACU75912">
        <property type="protein sequence ID" value="ACU75912"/>
        <property type="gene ID" value="Caci_7082"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7082"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="OMA" id="GCIGGDR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="772"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="990" mass="105016" checksum="2EDF9448EC42972E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5H0</accession>
    <name>C7Q5H0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797505.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8968"/>
    <dbReference type="EnsemblBacteria" id="ACU77781">
        <property type="protein sequence ID" value="ACU77781"/>
        <property type="gene ID" value="Caci_8968"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8968"/>
    <dbReference type="eggNOG" id="COG2206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105441_0_0_11"/>
    <dbReference type="OMA" id="WAHTQGV"/>
    <dbReference type="OrthoDB" id="1433958at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="20229" checksum="6E61AD72BE8BA13B" modified="2009-10-13" version="1">MSEYDAAFELAEEALAAELPRRWAHSQGVAERAVELTPLLTDRAHVLAASAILHDIGYSSRAKVTGFHPLDGARYLRDVGGFDDVVTRLVAHHSMAIIEADLRGLSEELVREFPVPGDALLMDALIFCDMTTTPDGARTTSSSRIEEIAGRYGADSIVGRFIGLAEPHIHAAVRRVEDAKAGIRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5R1</accession>
    <name>C7Q5R1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly (3-hydroxybutyrate) depolymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1082"/>
    <dbReference type="EnsemblBacteria" id="ACU70008">
        <property type="protein sequence ID" value="ACU70008"/>
        <property type="gene ID" value="Caci_1082"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1082"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042524_0_0_11"/>
    <dbReference type="OMA" id="KGCFDWW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980615" evidence="2">
        <location>
            <begin position="36"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="36528" checksum="76CE34A1A6334B74" modified="2009-10-13" version="1" precursor="true">MVRSVRMLRVTRRWAALWALTLFAAMAVPTTQASASGGLHTVSPVAGSLSGHQISGVYVAGISSGGYMAGQLQVAYSSRIKGTAVFGAGPYYCAENNAAEALYGCAANTYPDYLSTLEADASLWSAYGWIDPISHLSGRPVWVYHGSQDTAIAASVSKDGASFFSHFGAHVTSVTGTGAGHAWVTPYGSNSCGTTGSPYLNNCGTDPEHDMLTALLGSVTAENTGPLTGTLTRFNQNAYALGGSAGALDLSSAGFSYVPHSCATGSTCRLLVALHGCDQGYDTVGTAFVDEANLNQYADTNNMIVLYPQATTGASNPLGCWDWWGYLGATNYPIQGGAQIESIMNMVDALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5U4</accession>
    <name>C7Q5U4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70041">
        <property type="protein sequence ID" value="ACU70041"/>
        <property type="gene ID" value="Caci_1115"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1115"/>
    <dbReference type="HOGENOM" id="CLU_1341246_0_0_11"/>
    <dbReference type="OrthoDB" id="2116382at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="22581" checksum="1802D90491AF4F95" modified="2009-10-13" version="1">MEGAAPFLEPGESVYYGFVLKLDDTIPETPRELMIAIEGQHRVLGGINRADRKLNKGLKWALNPLDAMNERIAEKGTEALNRKLAGPVFLGGWESQAGWFIRYARATREDYGPGSWGVLTDRRYLIFRAGRAGGSSMRLVHAVPRTAIAGIRTEGTKDAALHGRTPRAELHFTDGSMVATMMPTKQGQRVAEILAVQQQHQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Y7</accession>
    <name>C7Q5Y7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785378.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1158"/>
    <dbReference type="EnsemblBacteria" id="ACU70084">
        <property type="protein sequence ID" value="ACU70084"/>
        <property type="gene ID" value="Caci_1158"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1158"/>
    <dbReference type="eggNOG" id="COG2130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_29_2_11"/>
    <dbReference type="OMA" id="GKDKCDY"/>
    <dbReference type="OrthoDB" id="474248at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="19"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="35591" checksum="7E18F0613B183938" modified="2009-10-13" version="1">MSVASREWQLIARPVGEPKDSDFRLVSTEVADPGPGEVLVRNTWLSVDPYMRGRMDDVPSYIPPFQLNEAMTGGAVGVVVAAGDGAAVPVGTTVQHFEGWREYALLDGTKVQPLDVTLAPPQAYLGVLGVTGLTAYVGLTEIAPVKEGEVVFISGAAGAVGSVAGQIAKKLGAAKVIGSAGGPEKARRLKEDFGFDAAIDYREGQLRAQLKQAAPEGIDVYFDNVGGDHLDAALTRMNLFGRIALCGAISAYNEKERPSGPAHLSNAIGKSLTLRGFTIGHHMKTFPEYIGKAAGWLADGSLRADETVVDGIENGLNAWFGLMSGANTGKMLVRLPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q608</accession>
    <name>C7Q608_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785399.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1180"/>
    <dbReference type="EnsemblBacteria" id="ACU70105">
        <property type="protein sequence ID" value="ACU70105"/>
        <property type="gene ID" value="Caci_1180"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1180"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_8_0_11"/>
    <dbReference type="OMA" id="MTIMTII"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="105"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="35566" checksum="6F0C781F3CFE6DF9" modified="2009-10-13" version="1">MTTLTSADSATPQAPAGAPAPGRRRGRGAVWRSFLTNRKANVGFGMFFVLLVMAVFPSLFTSVSDPTAPARFTPRLTPSGAHWFGTTSLGQDIWALFVYGAREPLIIAVVAGGLATVISVLVGVSAAYLGGIPDNVLSFITNVVLVIPTFPLVIVLSAYAGKPTLTIMVAVLVVTGWSYGANQMRAQALSLRNRDFLESSRVRGERRSYIIVFEMLPTMISLIIANFLGAALYSVLAAAGLQFLGLGDPNSDSWGTMLYWADSQSALESGTAWWAVLPAIGIAVLGVAFALMNYAFDEISNPALRPVRRQRGKLGVRRRPGSARTAAVAGGGAGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q657</accession>
    <name>C7Q657_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787356.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3154"/>
    <dbReference type="EnsemblBacteria" id="ACU72063">
        <property type="protein sequence ID" value="ACU72063"/>
        <property type="gene ID" value="Caci_3154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3154"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_2_2_11"/>
    <dbReference type="OMA" id="ILDDVHW"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1089" mass="112219" checksum="ECE66492FE602C31" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6G8</accession>
    <name>C7Q6G8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793732.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5144"/>
    <dbReference type="EnsemblBacteria" id="ACU74003">
        <property type="protein sequence ID" value="ACU74003"/>
        <property type="gene ID" value="Caci_5144"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5144"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_4_1_11"/>
    <dbReference type="OMA" id="WLRRCNR"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="852"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="918" mass="97509" checksum="408A84C5F8751AAB" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S3</accession>
    <name>C7Q6S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase LigD, polymerase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793837.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5249"/>
    <dbReference type="EnsemblBacteria" id="ACU74108">
        <property type="protein sequence ID" value="ACU74108"/>
        <property type="gene ID" value="Caci_5249"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5249"/>
    <dbReference type="eggNOG" id="COG3285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008325_1_2_11"/>
    <dbReference type="OMA" id="CCEVALW"/>
    <dbReference type="OrthoDB" id="2061599at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd04863">
        <property type="entry name" value="MtLigD_Pol_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014145">
        <property type="entry name" value="LigD_pol_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033649">
        <property type="entry name" value="MtLigD_Pol-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02778">
        <property type="entry name" value="ligD_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="292" mass="31810" checksum="6F286B90EDD4D50A" modified="2009-10-13" version="1">MSPDARASQTVEIDGRSVKLTNLDKVLYPDDGFTKGEILDYYAHIAPVMLPHLAGRPVTFIRYPDGVDTSGFFAKHAPAHRPSWIRTADIAATSSGKQVEYVLIDDLPSLMWAANLAAIEFHVPQWRVSDQQHHDLLVLDLDPGAPATVVDCVRVALAARDLLATHDLELRAKTSGAKGLHLYAALTDVTGEQARELAHTIARALEGTHPDLVVSSMSKAERPGKVFVDWSQNTHAKTTIAPYSLRATPHPAVSTPVTWEQLAAAKHPEDLRFPPARALEQVAEHGDLLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T3</accession>
    <name>C7Q6T3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane protein interacts with FtsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7116"/>
    <dbReference type="EnsemblBacteria" id="ACU75946">
        <property type="protein sequence ID" value="ACU75946"/>
        <property type="gene ID" value="Caci_7116"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7116"/>
    <dbReference type="eggNOG" id="COG0670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1259641_0_0_11"/>
    <dbReference type="OMA" id="ASMFFHF"/>
    <dbReference type="OrthoDB" id="1574251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="218" mass="22968" checksum="1CABCF4F542B0192" modified="2009-10-13" version="1">MYDTTTARRGYGISTNTLFARTMAFVAGTAALFALGAYTGRNLNHGAGFIGFIAAFACLIAMRFTAARSPQATVLLLGAFGLLMGIAMAPTLVYYATTNPTALWQAGAATALFIGALGSAGYATERDLSGVARASFWALVALLIFGVVAIFVRIPHASVIYSVAGLVIFAGFTLVDFQRLRRVQNIASAPLLAASIFLDILNVFLFFLSLFGGGGRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7I5</accession>
    <name>C7Q7I5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3271</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787471.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3271"/>
    <dbReference type="EnsemblBacteria" id="ACU72178">
        <property type="protein sequence ID" value="ACU72178"/>
        <property type="gene ID" value="Caci_3271"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3271"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OMA" id="MIMGYRL"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="60226" checksum="87C98AC4474EB5E6" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7J6</accession>
    <name>C7Q7J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787482.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3282"/>
    <dbReference type="EnsemblBacteria" id="ACU72189">
        <property type="protein sequence ID" value="ACU72189"/>
        <property type="gene ID" value="Caci_3282"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3282"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2104573_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="115" mass="12693" checksum="76E9E04591D07FC1" modified="2009-10-13" version="1">MKLASISGITQHSADLDRTVAFYESLGFRVGKRDEKQVTLYVNWFWIIFSAAEGPVEPGTASAVHLKVDDIQQAYEEVVAAGHKPSGEPAKRTGGGSEFELTDPDGYRLVLFYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7L2</accession>
    <name>C7Q7L2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787498.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3298"/>
    <dbReference type="EnsemblBacteria" id="ACU72205">
        <property type="protein sequence ID" value="ACU72205"/>
        <property type="gene ID" value="Caci_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3298"/>
    <dbReference type="HOGENOM" id="CLU_2022548_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13267" checksum="F044B924471072DE" modified="2009-10-13" version="1">MAEHDPAPQDPRYAELNDVLDTQRRLITELCETIGRQATLISELQEDLRGGRGWKPKGRSRHTGATYEGLGVRTEAILRLAEAEAASLRDEARQDAAARIAAAELEVARIRSEGGGSGETEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U8</accession>
    <name>C7Q7U8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5256</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5256"/>
    <dbReference type="EnsemblBacteria" id="ACU74115">
        <property type="protein sequence ID" value="ACU74115"/>
        <property type="gene ID" value="Caci_5256"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5256"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="GRTHRHF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="3">
        <location>
            <begin position="40"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="43365" checksum="BAE1D587EDC57778" modified="2009-10-13" version="1">MIDHPDPVPYPGAMNSPAARPTPATSATVRELNLRTVWRVIGENAPISRAEISRATGISKPTVSAVLEDLLQIGLVVETADASRGFTYGAVFFKPRPEAAHAVAFDVGARHLRAALVGLDGTEVVRRDAEVEGRSAEEMVAAAVDLARELVEAAGVAPASVQHAVVGVPGVVDQRDGRVWQATNVPGMDGFTARERFSEALQIPVTVENDINLAAHGEYARGSGGTADSFLFLSIGTGVGAGLVLGGNLLRGFKGAAGELDSAFEPDIVEGPDGPEPEVPPMMDPCAQAILQYAAEKLPGELSDDQELTMERVFELARADDAAAQDVVREEARRIANYAAVASAVVDVELVVLGGGIGLNGDLLLTPVAERLAGRLPYPPRLETSALGSGAVLAGAEALAASLTVEQLIRDYFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z3</accession>
    <name>C7Q7Z3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793889.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5301"/>
    <dbReference type="EnsemblBacteria" id="ACU74160">
        <property type="protein sequence ID" value="ACU74160"/>
        <property type="gene ID" value="Caci_5301"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5301"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009955_0_0_11"/>
    <dbReference type="OMA" id="HASVAHQ"/>
    <dbReference type="OrthoDB" id="1245649at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="635"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="897" mass="94519" checksum="8273820AA70ECFF4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8F6</accession>
    <name>C7Q8F6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D12 class N6 adenine-specific DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7315"/>
    <dbReference type="REBASE" id="21660">
        <property type="entry name" value="M.CacDORF7315P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76144">
        <property type="protein sequence ID" value="ACU76144"/>
        <property type="gene ID" value="Caci_7315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7315"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_4_0_11"/>
    <dbReference type="OMA" id="SRWYPKT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="35646" checksum="CF1F489DC86D4C5D" modified="2009-10-13" version="1">MPQDVVDKPGLLSDRRFFDQSVVSPLRYPGAKRRLTPVIQGLIRANVPPPRLFVEPFCGGASTALKVAGEEFVDHIILADADPLVAAFWYTAAFDTAWLIAAMWEEPVTLDRWDWWRLGTPRGRRDRALKCLFLNRTTFSGILHGRAGPIGGRAQESKYKIDCRFGKEGLERRLRAVGDLATTGRLLDVWNTDWRLTLTRLFREYGHLDPDEIAVYLDPPYVAKAPFLYEWSFESDEHASLAQALCRSGRFRWLLSYDDNPTIRDLYQGVSGVTRLSVPHLYTAAGSSNRAVRDELLVTNYPDLPASERYRAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8S7</accession>
    <name>C7Q8S7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785636.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1419"/>
    <dbReference type="EnsemblBacteria" id="ACU70342">
        <property type="protein sequence ID" value="ACU70342"/>
        <property type="gene ID" value="Caci_1419"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1419"/>
    <dbReference type="eggNOG" id="ENOG5033757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_833401_0_0_11"/>
    <dbReference type="OrthoDB" id="2028133at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="34367" checksum="7D8AD765D897F71A" modified="2009-10-13" version="1">MANPAALSQAETAGAITAPAGETLVPEAVAPDGSSFVAIEGSSVQNLDKLVLSRGHGSNLQTVSTLAAPYAGYGQMSFDGRWLVFMANQSQDITGAWDLYAWDSQGTAAPHIIASETVATPNAPVEWPELRNGKATWVQGVADGTQQVHLYDLAAGQDKVVHTGHIGASVLAGDLLVWTEALHIDGPVTLAAISIGTGAPASLPGPVAQVQTSPATLASDGTTWAWTSADYLTLYTWRAGMPAAVTVHTTTEGNPMDSVGVAGDVVTWTDSTATFAANVKTGSFTQVTKQYGSALTNGGAIMVYYPLGDVKSPGLKYDVFLLKTSDLAGLATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8V5</accession>
    <name>C7Q8V5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785664.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1447"/>
    <dbReference type="EnsemblBacteria" id="ACU70370">
        <property type="protein sequence ID" value="ACU70370"/>
        <property type="gene ID" value="Caci_1447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1447"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="HEDFILV"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="33632" checksum="4DB107B6FBD9991D" modified="2009-10-13" version="1">MDLLAHLRYFRVVAEEQHFGRAATRLRLAQPSLSQRIQRLEREFGVRLFDRGRGGAVLTPAGRLVLAQSETVLDAADRLQSVVGRLQDGEAGTLRAAVPAHLGGAAVAALLTAFQERSPGGELDLRELTTAEQTAELAAGTLDAGIVRHPCLAAGLAFGPMLHQPLGVLLRANDPLAVEPEVDLRALTGRALAMPPRTNSPALHDETLTACARHGFTPTAVRTVEGLDFTRALIMAGADLIALIPAPPPEPGTAWRPLTGHPLSWRTSTTWRAGHDGPAVRVFADAADAALRTHAGMYAASAERPRAARPETEFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X9</accession>
    <name>C7Q8X9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787592.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3393"/>
    <dbReference type="EnsemblBacteria" id="ACU72299">
        <property type="protein sequence ID" value="ACU72299"/>
        <property type="gene ID" value="Caci_3393"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3393"/>
    <dbReference type="HOGENOM" id="CLU_2153806_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="12744" checksum="72721BEC5FCF75B6" modified="2009-10-13" version="1">MGPWKARRRRAAYSRLIAKVSEHDVIWAAEEIVGTAWMAGLVDAERQAASRRASGRVRDRHEGLRRFAERERAAWEQAEWMRTLEVLADRDLLAEAARTAGVQEGLTHEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q974</accession>
    <name>C7Q974_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pyridine nucleotide-disulphide oxidoreductase dimerisation region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3488</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792123.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3488"/>
    <dbReference type="EnsemblBacteria" id="ACU72394">
        <property type="protein sequence ID" value="ACU72394"/>
        <property type="gene ID" value="Caci_3488"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3488"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_1_2_11"/>
    <dbReference type="OMA" id="MSKHYDY"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0274">FAD</keyword>
    <keyword evidence="2 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="11">
        <location>
            <begin position="4"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="10">
        <location>
            <begin position="355"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="8">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="478" mass="51459" checksum="E4EEE83452901F12" modified="2009-10-13" version="1">MKHFDLVVIGSGSGDTVIGDRPAGWTVALVEDQAVGFGGTCLNVGCIPSKMFVHTADLAEDARAANAFGVDLPAPAVRWLAIRKRVFDRIDQRSADGLRDSRAGGPNLTLFEGKGQFTGPNTLLVNDGETISADRFVIAAGSRPIVPDVPGLQDAGFLTNETIMRVEKLPERLVILGAGAIAAEFSHVFSALGVHVTVISRSGSMLTREDEDVSQLFTGIARRKWDLRQRREATRVERTSTGIRVHLRDPDGGDGDDVDDVESVQEFVEGDELLVAVGRRSNADRLNLSAAGVATHPDGRIAVDSRQRTNVPGIFAIGDVSSEHQLKHVANHEARVVAHNFSHPDEPTESDHRFVPHAVFTSPQIASVGLTEQRARAEGVPYVVGKRDYSEIAYGWAMNDPEGFAKVLADPQTGRLLGAHIIGPQASVLIQPLIQAMSLGQDAATVARGQYWIHPAMSELVENALLDLPQRSAKSPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E7</accession>
    <name>C7Q9E7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alkyl_sulf_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794022.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5434"/>
    <dbReference type="EnsemblBacteria" id="ACU74293">
        <property type="protein sequence ID" value="ACU74293"/>
        <property type="gene ID" value="Caci_5434"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5434"/>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169722_0_0_11"/>
    <dbReference type="OMA" id="MATIEEC"/>
    <dbReference type="OrthoDB" id="1792009at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alkyl_sulf_C" evidence="1">
        <location>
            <begin position="30"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="12125" checksum="4BB2EAADC0C8F057" modified="2009-10-13" version="1">MATIEECREALKEFAGNLGDMDESSKKLVRTVSLKVPDLDVTFHGTLREGTLEDVTTEPRDRAQIRLTIKSDDLIALVAGNLNFASAWARGRVKLEASISDLLRLRKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9N3</accession>
    <name>C7Q9N3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795930.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7375"/>
    <dbReference type="EnsemblBacteria" id="ACU76202">
        <property type="protein sequence ID" value="ACU76202"/>
        <property type="gene ID" value="Caci_7375"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7375"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_7_2_11"/>
    <dbReference type="OMA" id="YDNPEPL"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30075" checksum="48570B567111E907" modified="2009-10-13" version="1">MEVGIGLPISAPELLLDWARAADTGPFTTLGLLDRLVYDNPEPLIALSVLAGATRRIRLQTEVLLAPLRDPVLLAKQAATLDRISEGRFVLGLGVGGREDDHEAAGTDLRTRGRLLDRQMAVMQKIWSGAPYSDTVGPIGPLPYRAGGPQVLFGGFQPAALKRVARFGDGFLAAAPPSWIGSLIDTVHRSWAEAGRSGVPRIVAQANAALGPQIVVDDARTAMAAYYRFAGDRADQMVAGMLTTEAAIRQTIAQYADLGVDEVMLYCYGADPGQVDRLAEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA02</accession>
    <name>C7QA02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type III restriction protein res subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785694.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1477"/>
    <dbReference type="EnsemblBacteria" id="ACU70400">
        <property type="protein sequence ID" value="ACU70400"/>
        <property type="gene ID" value="Caci_1477"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1477"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020861_2_0_11"/>
    <dbReference type="OMA" id="HLKKQWA"/>
    <dbReference type="OrthoDB" id="458022at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="35"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="599" mass="66063" checksum="769E31201A2D2A8C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA59</accession>
    <name>C7QA59_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rlmN</name>
        <name evidence="14" type="ordered locus">Caci_1536</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785751.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1536"/>
    <dbReference type="EnsemblBacteria" id="ACU70457">
        <property type="protein sequence ID" value="ACU70457"/>
        <property type="gene ID" value="Caci_1536"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1536"/>
    <dbReference type="eggNOG" id="COG0820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_0_1_11"/>
    <dbReference type="OMA" id="QVGCSLD"/>
    <dbReference type="OrthoDB" id="1111428at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="142"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU70457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="42867" checksum="2AC773FD091E1D49" modified="2009-10-13" version="1">MSAEAPATPVPAVDTDAVESVDVTIAPKPPRPGELTFTSPRRAKPPRHLADLTSAERKKALSELGHQGFRAAQVSQHYFGHLADDPAQWSDVPAAKREELAGILTPRLLTPIREQTADNGTTRKTLWRLFDGATVESVLMRYRDRTTMCVSSQAGCGMNCPFCATGQAGLTRNMSTGEIVEQVVAGARTMARGEVPGGPGRVSNVVFMGMGEPLANYKAVIGAVRRLTEPVPDGLGLSARHITVSTVGLVPAIEKLTAEAIPVTLAVSLHAPDDELRDTLVPVNTRWNVSEVLDAAWRYASVTKRRVSIEYALIKDINDQAWRADRLGRMLRNKLVHVNLIPLNPTPGSKWTASRPQDEAEFVRRLQEWGVPVTVRDTRGRDIDGACGQLAAAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC5</accession>
    <name>C7QAC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3518"/>
    <dbReference type="EnsemblBacteria" id="ACU72424">
        <property type="protein sequence ID" value="ACU72424"/>
        <property type="gene ID" value="Caci_3518"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3518"/>
    <dbReference type="eggNOG" id="ENOG5032YMI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_191981_0_0_11"/>
    <dbReference type="OrthoDB" id="2053552at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9784" checksum="850E7796451A81F4" modified="2009-10-13" version="1">MTEPERQLTVPDYEPGGALRFAWAEGFRIEVDASDGEVVIRANSAGLVSLAQHCLTLAQAAVPAGSHLHLTDSVELEPGSGDLIIERASEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD0</accession>
    <name>C7QAD0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PEP-utilizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3523</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792158.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3523"/>
    <dbReference type="EnsemblBacteria" id="ACU72429">
        <property type="protein sequence ID" value="ACU72429"/>
        <property type="gene ID" value="Caci_3523"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3523"/>
    <dbReference type="eggNOG" id="COG1080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705801_0_0_11"/>
    <dbReference type="OMA" id="MMCTAEL"/>
    <dbReference type="OrthoDB" id="519524at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP-utilizers" evidence="4">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="5">
        <location>
            <begin position="199"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="406" mass="43104" checksum="913E51931EC9CA47" modified="2009-10-13" version="1">MDRRRIQGSLLTGGTESTVRGVCNRTDSPLEGSILVAPSLEAGLYDAIVAASAVVCSSGGRTGHMQSICRGRGIPVLRIDHDDLADLAGEVTLHLDSESITIGPALSAHAPEAGTEAPSLQNLGSACAVIADLRDIDTINACGPGAAQVESFFIREEFLCLAAGLSPLDAFGGGPTDVTGYGKAVADRLCMFVDALLPSQRIVLRMLDLRSDHAASVTERAPITIEPNPELGLHGARWLLGSAAYRDALHAVLGALHDQLGDAARRVHLSVPFLTDAEEFTQVMDHLQLPEEVPVAAFIETPAAVHAAEALCAAGASELFLGTKDLAQFYLAADRNNHLVAESYQTRHPAVLDGLDRVITAARTAGTPVRVFALHADLKHYLDRLPTPDGYMMCTAELERMILQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG4</accession>
    <name>C7QAG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase domain protein FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3558"/>
    <dbReference type="EnsemblBacteria" id="ACU72463">
        <property type="protein sequence ID" value="ACU72463"/>
        <property type="gene ID" value="Caci_3558"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3558"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059021_1_4_11"/>
    <dbReference type="OMA" id="KPQRTEP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="25"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19374" checksum="BF165FF613B2D613" modified="2009-10-13" version="1">MTAALPATHLHSVQPIDGTMLRQVCGHFVTGVTVITSGEAGGESGGTTVNSFTSVSLDPPLVLFCLHNDSRLRAMVEDRRAFAVNFLAGRQEKVAWKFAGKQTANLSDVPHKRSIAGTPVLSDALAFLACTLVSQFAGGDHTIYLGEVVELGAARGRDPLIFFKGTLGALADEPHQTHYWDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAX1</accession>
    <name>C7QAX1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794173.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5585"/>
    <dbReference type="EnsemblBacteria" id="ACU74444">
        <property type="protein sequence ID" value="ACU74444"/>
        <property type="gene ID" value="Caci_5585"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5585"/>
    <dbReference type="eggNOG" id="COG3591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050832_1_0_11"/>
    <dbReference type="OMA" id="GFWIANG"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980772" evidence="1">
        <location>
            <begin position="23"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="30643" checksum="F0BA417DB70AA754" modified="2009-10-13" version="1" precursor="true">MKFRRHGLIASTVLALSVMATACDGGGSNARTPAESASSSEAAAAKVVTHVLEPKPDDPHSLLHPGPPLTGAIPAGTTVNGKVSAQTFDGVPKVGAVFFGVGGVVSAHYCTGSVVQSGSGDLIVTAGHCVYNKLFGGWNNHIVFVPGYHDDTAPYGVWVATTAYLDSTWVASQNPDVDIAFLKVREVGGGTKTLESATGADTFSEAPGYTNAISIASYPLTAKKPVGCTATTKKYSDTQLELDCAGLPDGASGSPFIASGDRLVGVLGGYEQGGNSPTTSYSIYFSERIAKIYKATSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAZ0</accession>
    <name>C7QAZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794192.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5604"/>
    <dbReference type="EnsemblBacteria" id="ACU74463">
        <property type="protein sequence ID" value="ACU74463"/>
        <property type="gene ID" value="Caci_5604"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5604"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_5_11"/>
    <dbReference type="OMA" id="FILDAIH"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28132" checksum="EDABE905419510C7" modified="2009-10-13" version="1">MPNTSVSFYAGRDGARLAYRELGEGRPLVLLHGAIGDGTMWTRHGQAETFAGHGYRVILPDFRGHGSSDKPQGADAYPGDILTDDALALLEHLGLEEPEAKTETDSLHTPAAYDLGGYSLGARIVVRMLVRGATPGRAVVAGQGLQQVLGFGGGVGEMLRRIVTATEPFEPGSQDERTAAWLKAGEEDPVALLHAVESVVATPVEDLSRVQVPTLVAMGTEDARAESYEALIAALPNAAGARMPGNHGSAAAAPELVTAMVEFLTAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB43</accession>
    <name>C7QB43_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796059.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7509"/>
    <dbReference type="EnsemblBacteria" id="ACU76334">
        <property type="protein sequence ID" value="ACU76334"/>
        <property type="gene ID" value="Caci_7509"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7509"/>
    <dbReference type="eggNOG" id="ENOG50332H3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071246_0_0_11"/>
    <dbReference type="OMA" id="KWCVLAV"/>
    <dbReference type="OrthoDB" id="1896237at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025498">
        <property type="entry name" value="DUF4389"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14333">
        <property type="entry name" value="DUF4389"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36837" checksum="A39B79ABCED09742" modified="2009-10-13" version="1">MSDQLPPAPPPPPEDPNQPPYGQQPPYGQQPGQQPPPYGQQPGQQPPPYGQQQPYGHPYGQQQGYPQYPQYPGGGNVYGELRREPEVQLDVQGLRPQRRWTVLIRLILAIPQLIVLYLLLVAGFFVLIVGWFAALFTGRLPAGIRDFLIGVLKYQIRVHGYLFLLVDEYPPFAFFEAPGYPIQIEVPEPTRLNPAAVFFRIILMVPGWIVTSVVGEGAAVVSFFVWIIMLFTGVQPEPAFGATSAMLRYESRFLGFSGMLTPTQPKGLFGDAPGAPEAAARRSPTRPLLLSSGARTLLIVMIVVGAIAAIFNGVFNSDNGSDSNSVKAPYTVSQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB66</accession>
    <name>C7QB66_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7532"/>
    <dbReference type="EnsemblBacteria" id="ACU76357">
        <property type="protein sequence ID" value="ACU76357"/>
        <property type="gene ID" value="Caci_7532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7532"/>
    <dbReference type="HOGENOM" id="CLU_1101339_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="26208" checksum="FF4B3EA33A01FB07" modified="2009-10-13" version="1">MSALYPAPSPAATTWLATLRTTLASLADQVRHAPPIDVETLAAYLESESPEAAELGDAVLATLEEFEPVISGLTMSFGLVPSTMLIALGRGEEIGEIDPVVASALGEVGEIRPLTSSGTVTIEKDGRATTLIAGTTVAAPIGPVRISWPDRDDVWLCAVPAAANPVATARAALERILPHAGVGRAHLRTAPAGNRRAAPTSTPRTAPAALHAALLSIDPTADPDLVMARLEGWRAALEQLHRGAVAVHWEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBA6</accession>
    <name>C7QBA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796122.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7573"/>
    <dbReference type="EnsemblBacteria" id="ACU76397">
        <property type="protein sequence ID" value="ACU76397"/>
        <property type="gene ID" value="Caci_7573"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7573"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008901_0_1_11"/>
    <dbReference type="OMA" id="CAVDTGW"/>
    <dbReference type="OrthoDB" id="983098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="454" mass="49498" checksum="0EBF84AAABFE92DF" modified="2009-10-13" version="1">MDPEELSRALSALTALPVDDPVRLRVERVAESFVRDGRRRRQKEQRLRRQAADRAVLAASATGAAERREDAPLEVPDDAHRADPDADSVGTLLRPQRCYVCKRHYTRVSAFYHQLCPSCAAENLAWRSARTPLDGRRALVTGGRVKIGFHVALMLLRDGAAVRVATRFPHDAIRRFRQVEDSAKWLDRLTVTGLDLRDPRQVIELCDGLLAEGEPLDILINNAAQTVRRPESSYAPLIAAERSAAAELSGGGGLRELAPIAGYHGAGADAVPHSAELAVAGGAVDENGLLPDPSPHNSWSAEIGELDAVELLEVHLVNAVAPALLADRLLPLMTGSPSARRYIVNVTAVEGRFEVRNKTAGHPHTNMAKAALNMLTRTSAEALARRGVYLSSVDTGWITDEKPMPRKARHAESGFRTPLDIVDGAARIYHPIVSGERGEPLFGVFLKDYRAVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBI7</accession>
    <name>C7QBI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA methyltransferase, TrmA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1643</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1643"/>
    <dbReference type="EnsemblBacteria" id="ACU70564">
        <property type="protein sequence ID" value="ACU70564"/>
        <property type="gene ID" value="Caci_1643"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1643"/>
    <dbReference type="eggNOG" id="COG2265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014689_7_0_11"/>
    <dbReference type="OMA" id="FYAGDMK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="455" mass="48948" checksum="7B9C7A5A4C5F3CDD" modified="2009-10-13" version="1">MKRPADRRRSSDHAAQARPSGDAVGTRIEVEVGAPGHGGFCVARHEGRAVFVRHALPGERVVAEVTEGDSKDSFWRADAVEVLEASEDRVEAPCRYAGPGLCGGCDWQHASYEAQLRIKGEVVAEQLRRLAKLDREVVVEEVASPFGWRTRVQFAVDPDGSLGFRKHRSHEVVPVEECAIASSGVDEVGALGRQWPGVETVEVIAATGSNDRALVVTPKRGESMPFVDADVKASVLRGVSRNTHISGVQRIHGRPYVREVAEGRTWRVSGSGFWQVHPAAPDVLTEAVLDFLDPKDGDVALDLYCGVGLFAAPLAEAVGESGAVLAVELDRQAVRDAAHNLGFADDAEESTEFPWVDLVEGSVDEVLADEGYVPDRADVVVLDPPRAGAGRDVCARIAALGPRAVAYVACDPAALARDVAYLAEAGYELTDLRAFDLFPMTRHVECVALLEPAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBJ1</accession>
    <name>C7QBJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1647"/>
    <dbReference type="EnsemblBacteria" id="ACU70568">
        <property type="protein sequence ID" value="ACU70568"/>
        <property type="gene ID" value="Caci_1647"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1647"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061533_2_0_11"/>
    <dbReference type="OMA" id="CHGVLEY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_12" evidence="2">
        <location>
            <begin position="48"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="26935" checksum="BEAFA22365D44AFB" modified="2009-10-13" version="1" precursor="true">MADSAASATATSATSAAPAAARRDRARTAVLWQALRTVLDASGPRDVLDVGGGTGGFAVPIAELGHRVTVVDPSPDALAALERRAAESGVPKEALRAVQGDLAGLLEHVEPGSVDLVLCHGVLEMADDPAAGLATVADVLRPGGVVSLLAANRTAAVVARALGGHFAEARRALADPTGRFGAQDPLAARFDEEQLSRLLREARLTVQSVHGVRVFTDLVPGALVDADPQAASDLAALEAAVADRPEFRAVAGRLHLLARKIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC73</accession>
    <name>C7QC73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794250.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5662"/>
    <dbReference type="EnsemblBacteria" id="ACU74521">
        <property type="protein sequence ID" value="ACU74521"/>
        <property type="gene ID" value="Caci_5662"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5662"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_793871_0_0_11"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="349" mass="36208" checksum="587224482C3C1D80" modified="2009-10-13" version="1">MANGGMAAGTAGHNAAVDDNLGQGAPADHRPSENTAANRSGKTVTHRSASQSTAADHAPSQHAAVDRSLSETAAADRSPSQSTVTEVRAATAGGPSISVQPRRTRATGYLAVAGDLAPRDRRASDVEAILCDLDDTLYPQAAWLDGAWSAVAAAGARWGVEERAFLAALRADAAVGSARGGIIDRALVDVGVGGGAELVAELLAAFRAYRPVRLEPYPGVREALVRLRVAGVRLAVVTDGDVEVQAWKVRALGLSAFFECVVVSDALGGRGVRKPSAVPFLAAVEGLGVRPERCVVVGDRPEKDVMGALGADIRAVRVKTGEYRQVADVAGTWHTAADFPAAVDWLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCJ8</accession>
    <name>C7QCJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796186.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7637"/>
    <dbReference type="EnsemblBacteria" id="ACU76461">
        <property type="protein sequence ID" value="ACU76461"/>
        <property type="gene ID" value="Caci_7637"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7637"/>
    <dbReference type="HOGENOM" id="CLU_2022549_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13099" checksum="086A135B3F93AA6D" modified="2009-10-13" version="1">MDLIMVAVQRAGFAGDRGLAAATLRYALQAVSGDSPRALEHAHVVVDEAGVFPARLVAGLYLASGPDVPYSVRDTATALVRRALTTSPMLEDWSVDWVEGPYGYELLDSLDTLEDSQSPLHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCR5</accession>
    <name>C7QCR5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796253.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7704"/>
    <dbReference type="EnsemblBacteria" id="ACU76528">
        <property type="protein sequence ID" value="ACU76528"/>
        <property type="gene ID" value="Caci_7704"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7704"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_1_0_11"/>
    <dbReference type="OMA" id="PCRNAYL"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="133"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="23015" checksum="E82DA23616ADB39D" modified="2009-10-13" version="1">MELASYADRAVSLVNTADPYRHRDTLTTCEQAKELLAPEGRCRVTNADVAELRAIRDRLREVFDAAESGRVPRAVQVLNSLMKQYPIRPVVTDHDGASWHLHLAEGAPTIAAVYGAKAAMGLAVQATELGFDRLGVCQAAPCREVFIDTSTNRSRRYHSDRCATRANVAAYRARRKEQARVAGEAEAAANAANAPGTATAAGAKVMAGAGSAAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD20</accession>
    <name>C7QD20_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lysine N-acyltransferase MbtK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mycobactin synthase protein K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis; mycobactin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786024.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1809"/>
    <dbReference type="EnsemblBacteria" id="ACU70730">
        <property type="protein sequence ID" value="ACU70730"/>
        <property type="gene ID" value="Caci_1809"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1809"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039848_4_2_11"/>
    <dbReference type="OMA" id="WEIYRAD"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="UniPathway" id="UPA00011"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="194" mass="21666" checksum="3F1238BEA751CD93" modified="2009-10-13" version="1">MTITNPVQTRAGWLLPTPFGRFEMEQLRPLKDLPVLHRWMNDPEVAAFWDLDGPREVLDRHIAAQLSSAHSEPCLGRLDGEPMSYWEVYQADQDPLAAYYSARRGDVGIHVLIGPGAYRGRGVGSTLIRAVADWALSRTASSRVVAEPDLRNRRSIQAFANAGFAPRGVLDLPDKQAMLMVYDRTLIPETRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD46</accession>
    <name>C7QD46_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminomethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786050.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1835"/>
    <dbReference type="EnsemblBacteria" id="ACU70756">
        <property type="protein sequence ID" value="ACU70756"/>
        <property type="gene ID" value="Caci_1835"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1835"/>
    <dbReference type="eggNOG" id="COG0404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_2_11"/>
    <dbReference type="OMA" id="YPLHGQD"/>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="7">
        <location>
            <begin position="10"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="8">
        <location>
            <begin position="289"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="369" mass="39773" checksum="7097B617033ABCE7" modified="2009-10-13" version="1">MTSDPLTSPLHARHVALGAKMSDFGGWDMPIEYSRTGGVLKEHAAVREQVGVFDVSHLGKASVTGPGAAAFVNSVLANDLQRIEDGQAQYTLCCDDATGGVVDDLIAYLNGPEDVFLIPNAANTSEVVRRLREAAPEGVTVQNRHRDFGVLAVQGPKSAAVLAELGLPTDHDYMSFTVASFENAPLTVCRTGYTGEHGYELVAPWDKTEALWDALQAAGEEFGIRPCGLGARDTLRTEMGYPLHGQDLSMEITPNMARAGWAVGWKKPAFWGREVLLAEREAGAKRLLRGIRAVDRAIPRAHMVVNDADGKQIGEVTSGTFSPTLREGIGLALLDREYTEGDTVYLDVRGKAAAFTVVKPPFVDVRTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDG3</accession>
    <name>C7QDG3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72756">
        <property type="protein sequence ID" value="ACU72756"/>
        <property type="gene ID" value="Caci_3862"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3862"/>
    <dbReference type="HOGENOM" id="CLU_3267494_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="41" mass="4690" checksum="69E9B6202CCEE6F0" modified="2009-10-13" version="1">MLEDDTTPLGSSRPSSNFAYEWLARHFHTLGSLKNPITFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDK7</accession>
    <name>C7QDK7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5773</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794360.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5773"/>
    <dbReference type="EnsemblBacteria" id="ACU74631">
        <property type="protein sequence ID" value="ACU74631"/>
        <property type="gene ID" value="Caci_5773"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5773"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_10_1_11"/>
    <dbReference type="OMA" id="IFRATIA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041678">
        <property type="entry name" value="TetR_C_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17920">
        <property type="entry name" value="TetR_C_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="21887" checksum="AD24D81BDED8D40F" modified="2009-10-13" version="1">MTAHQRDAVATREAILAAAVVEFTAHGYAGAGVRQIAERAGVTAMMINRYFGSKQGLFAEAVDRSFGPATVVGSERRGLMRDMARALAERTAPGAEGLDPFLLMLRCASDPEAVEIVRRGVEAHAGARLAGLIGGDEADVRAQLGLALVAGTWLMRVVVGTGALAAADDARLAELLGAMLAPLTQEADTRRAGDADADATDADADADADAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDM7</accession>
    <name>C7QDM7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ordered locus">Caci_5793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794380.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5793"/>
    <dbReference type="EnsemblBacteria" id="ACU74651">
        <property type="protein sequence ID" value="ACU74651"/>
        <property type="gene ID" value="Caci_5793"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5793"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_0_0_11"/>
    <dbReference type="OMA" id="IPYVGCD"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="137"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="37423" checksum="C2824A053484EF71" modified="2009-10-13" version="1">MDKLNIGIMFGGCSEEHPISVKSAREVAKNLDTSKYEPFYIGITRDGAWRLCDGPEENWENGASRPAVVSPDRGAHGLLVLDQGRYEAIRLDLVLPVLHGKLGEDGAIQGLLELAGIPYVGCDVQTSVLCIDKTLTYLVIQNEGIATPRFWTLTPDEKIDPNELPYPVFVKPARSGSSFGVSKVSGKDELSGAIEEARLYDAKVLIEEAVVGSEIGCAVLGTGEDLLVGEVDRVALTHGFFKIHQESAPETGSENATFIVPADIPAQSRALIQETAKLVYRALGCRGLSRVDFFLKEDGTVVLNEVNTLPGLTSYSRYPRMMAAAGFPMSEVIDRLVAVTIAGDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE25</accession>
    <name>C7QE25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7789"/>
    <dbReference type="EnsemblBacteria" id="ACU76613">
        <property type="protein sequence ID" value="ACU76613"/>
        <property type="gene ID" value="Caci_7789"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7789"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062440_2_0_11"/>
    <dbReference type="OMA" id="RFWADTW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="30921" checksum="F7B37675851C2C90" modified="2009-10-13" version="1">MSQAPAHTPDTAAHQPDPPRERYGDRLFRPERLDTEIPRLSARAAMYDDHTFGCLKALGVSPGWRCLDVGTGPGHVARWLAAAVGPQGTVTALDRSTRMLDTYAHPPNLDALEADALTAEPGRYDLVHCRLTLMHTPQRAALLARMASWVRPGGWLIVGDDVDFATHSSPHQALRQTFAAMRRMLNTTIGTDFHFARDYPGHLRELGLTPIGEQATTPTLRAGTAPNEFWLRTWDQLWPRMELDEAVYREARRLLQDPEVVDLSLTHITAWGRRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET3</accession>
    <name>C7QET3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72853">
        <property type="protein sequence ID" value="ACU72853"/>
        <property type="gene ID" value="Caci_3977"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3977"/>
    <dbReference type="HOGENOM" id="CLU_118476_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14001" checksum="6568813DE6F90923" modified="2009-10-13" version="1">MVCGTEIQGAVETILAASPAPTTTTTWTDHLYTCTYHLASGTLVLSVKESPDTASANTYLATLQRQLGSTTPLTGSEGLGNPGFQNAAGNVVVLKDDKTLHVDATGLAAASGPSKLSRADVAYEVTTDILGCWTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEW4</accession>
    <name>C7QEW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4016"/>
    <dbReference type="EnsemblBacteria" id="ACU72884">
        <property type="protein sequence ID" value="ACU72884"/>
        <property type="gene ID" value="Caci_4016"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4016"/>
    <dbReference type="eggNOG" id="ENOG502ZES2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_768813_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="360" mass="38211" checksum="0924096D79906FA0" modified="2009-10-13" version="1">MLMSVPTPAAPPPIRATYAYPAILAVYAAVFGAAAFTWTALLLYTYHALPEAWMAAILRHQNGADVVPAVLAGLAALMICAALITSERGKQIVVFNSPGRRVTALGIIAAALIPVEWALRHVQLLESDDLTPRIVELVGSAALAGALAVVLAAPEPAELGIGGRKHRSITEFYALARTSLLGLLGSLAAVNLILYGLKPPALVGPVGPGSGMVESFWFWIAVACVNAVVEEGICTAWLYALLHRAGRPRYEIYAVAVLARVGIHLYMGLPGLGAAIFALVNIRLFERTGRVAPLILAHACFDCATITGNRTVLYVFISAGALMLLYPPSFLPRRRATEQNRGDRPQHQPAMEAARTGGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEW8</accession>
    <name>C7QEW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4020"/>
    <dbReference type="EnsemblBacteria" id="ACU72888">
        <property type="protein sequence ID" value="ACU72888"/>
        <property type="gene ID" value="Caci_4020"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4020"/>
    <dbReference type="HOGENOM" id="CLU_2354615_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="96" mass="10867" checksum="B6088E3B50CF104F" modified="2009-10-13" version="1">MMTSCALAHRVAPEPLLDSAATSERYVILISGVFVRNICGAAAESTFRRWCRSPDVVMDGDLRTGFFWEWPDSRRTRIEIIPEPDEDRSVHTVVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEX3</accession>
    <name>C7QEX3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O = 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23436"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:137796"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-6-(5-phospho-D-ribosylamino)uracil + H2O = 5,6-diaminouracil + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:55020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:46252"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5873"/>
    <dbReference type="EnsemblBacteria" id="ACU74731">
        <property type="protein sequence ID" value="ACU74731"/>
        <property type="gene ID" value="Caci_5873"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5873"/>
    <dbReference type="eggNOG" id="COG3236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084247_1_0_11"/>
    <dbReference type="OMA" id="WMMAAKA"/>
    <dbReference type="OrthoDB" id="1726046at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="SSF143990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="3">
        <location>
            <begin position="8"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="18743" checksum="D8B14A624BEA9567" modified="2009-10-13" version="1">MTVKYLFFWGHTPNRPGTVGAECLSQWYPAPFEVDGLRFATAEHSMMWGKAQLFGDEQAAARIVAAGHPKEAKDLGRTIRKFDEDTWVAERVAIVTAGNVEKFRQNPDLLAFLLTTGERVLVEASPMDRIWGIGLASDDERAQDPARWRGLNLLGEALMAARKTLRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF39</accession>
    <name>C7QF39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794526.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5939"/>
    <dbReference type="EnsemblBacteria" id="ACU74797">
        <property type="protein sequence ID" value="ACU74797"/>
        <property type="gene ID" value="Caci_5939"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5939"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116668_0_0_11"/>
    <dbReference type="OMA" id="HAYAFAI"/>
    <dbReference type="OrthoDB" id="1598286at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="42"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="100"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16296" checksum="F578E5F72C5EA7B5" modified="2009-10-13" version="1">MTQDPDCYSCQNEARLPELPPREHVGSDDHWRVAHAFGAGVPGWLVLLPRRHVTAIADLTDAEAAGLGTWQVRLSRALHAVTGCEKTYVAQFAEAAGFGHVHFHIVPRSPDLPPELRGPRVFGLLGRGAQESVPDVRADEIALALRAALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFK1</accession>
    <name>C7QFK1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796503.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7955"/>
    <dbReference type="EnsemblBacteria" id="ACU76778">
        <property type="protein sequence ID" value="ACU76778"/>
        <property type="gene ID" value="Caci_7955"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7955"/>
    <dbReference type="eggNOG" id="COG0641">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_390115_0_0_11"/>
    <dbReference type="OMA" id="REANDRH"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026337">
        <property type="entry name" value="Mod_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026335">
        <property type="entry name" value="SAM_SPASM_FxsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023867">
        <property type="entry name" value="Sulphatase_maturase_rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43273">
        <property type="entry name" value="PTHR43273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04267">
        <property type="entry name" value="mod_HExxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04269">
        <property type="entry name" value="SAM_SPASM_FxsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="794" mass="86643" checksum="73AF1359C748F28D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFQ7</accession>
    <name>C7QFQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784291.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0041"/>
    <dbReference type="EnsemblBacteria" id="ACU68996">
        <property type="protein sequence ID" value="ACU68996"/>
        <property type="gene ID" value="Caci_0041"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0041"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045680_5_1_11"/>
    <dbReference type="OMA" id="WTNVRAH"/>
    <dbReference type="OrthoDB" id="1022681at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05830">
        <property type="entry name" value="Sortase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042003">
        <property type="entry name" value="Sortase_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="25915" checksum="63EB41DFB1F60BD6" modified="2009-10-13" version="1">MWAESARTAIRSVGEILITLGLVLFLFCAYQLFYTNVVADEAMKSEVSDLHKLWDAPVARAAAPRAANAFDTADSHGTAGAAFAILHIPRLGDKSIPVLQGTTLDLLGRGVGHYKDSAMPGRTGNFAVAGHRKTHGEPFRYLDEMRDGDLIVVETADSWYTYREDRDPFIVDPTDLGVVAPVPDHPGATPSRKLITLTTCNPWWASTQRMIVTGELIAQQPRSAGEPPAMTVNAPKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG42</accession>
    <name>C7QG42_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786312.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2100"/>
    <dbReference type="EnsemblBacteria" id="ACU71019">
        <property type="protein sequence ID" value="ACU71019"/>
        <property type="gene ID" value="Caci_2100"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2100"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_0_1_11"/>
    <dbReference type="OMA" id="MHIDQDI"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="143"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="41986" checksum="55DD78D8798689B4" modified="2009-10-13" version="1">MSGGYGGWTPQEPGGWIPPEPEPTVELRPPSRWAQLRGRLSGGRRDGGGPRPPRVRRFSWPKRILAGGLVLVLLVGGYATWLYFHASGEIRHENVISDYPGRPAEGKGTNWLLVGSDSREGLTSDQEDALHTGTGAVTGNTSRTDSMMILHSGSNGTSLISLPRDSYVTIPAWTDSKGKQHALSKNKLNAAYAFGDAPLLIKTIEVSTGVRIDHFAEVGFGGFVKVTDAVGGVHLCLDKPLKDELSGADLKAGCQTLNGAQGLAYVRDRYSDPLGDIGRMQRQRTFLAALAHKVSSTGVILNPFKLVPVLDNSLAAFKVDNGTNLSDLYDMFQHMKGVSGSNGHTIVVPIANEDYNVPGVGSCILWDKTKAGQLWSAVINDTTMPALSATGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG78</accession>
    <name>C7QG78_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4058"/>
    <dbReference type="REBASE" id="21664">
        <property type="entry name" value="M.CacDORF4058P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72923">
        <property type="protein sequence ID" value="ACU72923"/>
        <property type="gene ID" value="Caci_4058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4058"/>
    <dbReference type="eggNOG" id="COG0270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014695_1_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="438" mass="48642" checksum="38D6FC847FEF1547" modified="2009-10-13" version="1">MSAAVLEAPPDEELWLPPAYRQVRPQTGLTSTHLLAGGGGDTLGLWEAGFLPLYGGNHEAVCIESLIANWAGLGTEHELADIAHLAMSDLPSSDVLWASVICTEVSPAGRRSRYGGPMGVDRYGRPLGNRKFRRTRATALDVMRAAEYHRYRAIVVENVIDFVTRWELFGWWVMGMCLLGYRFQLVSVSAAHVGDEHNPAANQLRDRIYAVFTRLDVPIPDLSPRPASWCPTCRRTVRGEQRWRRAASRRPYPVGRHGHSYDYVCPSLCGSIVRPHVRPAAEAFDLDDLGEPLAAKSGPRKPSTTLRLEAALRYLTTDATRRHGARCLRPDGGRRLAVMEYRNHCDAASGWEPLTTVSAQGYHHAIVAAPEDWEPGAPLSIHDLTYRMITSREQARTQRFPDEYILCGTAADVRLQAGNAVPVNVARWIGERLADVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG4</accession>
    <name>C7QGG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional repressor, CopY family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4145"/>
    <dbReference type="EnsemblBacteria" id="ACU73009">
        <property type="protein sequence ID" value="ACU73009"/>
        <property type="gene ID" value="Caci_4145"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4145"/>
    <dbReference type="eggNOG" id="COG3682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119090_1_0_11"/>
    <dbReference type="OMA" id="ARQEENP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="14323" checksum="158289D85777A49C" modified="2009-10-13" version="1">MALRQFGELEAQVMDRVWRHNRPVLVRDVLSDLNTDRELAYTTVLTVMEKLRRKGWLRRQRTGRAYAYEAVGSREYYTARLMCDALATSDNQTVSFVHFLEQLSHEEAHALRTALEVRQLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS4</accession>
    <name>C7QGS4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell wall synthesis protein Wag31</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Antigen 84</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DivIVA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794683.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6099"/>
    <dbReference type="EnsemblBacteria" id="ACU74954">
        <property type="protein sequence ID" value="ACU74954"/>
        <property type="gene ID" value="Caci_6099"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6099"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062236_1_0_11"/>
    <dbReference type="OMA" id="RNKQFTT"/>
    <dbReference type="OrthoDB" id="875822at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007793">
        <property type="entry name" value="DivIVA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35794">
        <property type="entry name" value="PTHR35794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05103">
        <property type="entry name" value="DivIVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="60"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="210"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="347" mass="36402" checksum="984DA36BF860D3E9" modified="2009-10-13" version="1">MPLTPEDVHNKQFTTVRLREGYDEEEVDAFLDEVEAELTRLIRENEELRAKLAAATRAAASAAAAPVPMRREPTPIPAPAPPVPAPLPAPLPAPLPVPQAPQFQAPGGDSAARVLALAQQTADQAIAEARNEANKIVGDARGRADGLEREARGKADALERDAQEKHRVAMGSLETARAALERKVDDLRAFEREYRQRLKSYLDGQMRQLEASGGDDTMGSSMGSRAQLSPTGLSAPPPAPSGPPMPMQASLPPGMPQAQSPVGAGMNGGMGSTGSYQSAGNNGSNAAALTQTMAPIRPQMPSPMPPQQMGGGQQPPFMGSGNGLGQPPVPSQPSPMRGFLIDEDPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGT9</accession>
    <name>C7QGT9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_6114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794698.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6114"/>
    <dbReference type="EnsemblBacteria" id="ACU74969">
        <property type="protein sequence ID" value="ACU74969"/>
        <property type="gene ID" value="Caci_6114"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6114"/>
    <dbReference type="eggNOG" id="COG0772">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029243_0_2_11"/>
    <dbReference type="OMA" id="KLWWSNL"/>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="11" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="330"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="44020" checksum="3339A57ADE985F69" modified="2009-10-13" version="1">MSEQAAGSQASPLKNAVRALRARRAVLKSLFDLELTSYYLLVGAVLLLLGIGLLEVFSASSVNNLVNGRPMLSSIQNQAISAVLGLALMWGASRLPPRAYRALAYPALVGTVLALLLVLAVGSSHNGNKNWLIIGPLTVQPSEFAKLALVLWGADLLVRKEKLLTTWDHLLVPLVPGAVLIIALVMMGGDMGTSIIIVAIVFCLLFTAGAPGRLFSILLASAVGLATLAILMRPSRVRRFTNFLSPENDPGGTGYQAIHAFQALASGGWFGEGLGASKQRWGQLPEVQTDMIFAIIGEELGLIGALTVLALFLTIAYAGIRMALRTSDPFVRLVSASVTVWLAAQMMINLGAVTGVLPIAGVPLPFVSYGGSSLLPSLTAVGMLMSFARRRPEPLDPATVREQGVTAPRPSGVPADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH60</accession>
    <name>C7QH60_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796635.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8087"/>
    <dbReference type="EnsemblBacteria" id="ACU76910">
        <property type="protein sequence ID" value="ACU76910"/>
        <property type="gene ID" value="Caci_8087"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8087"/>
    <dbReference type="eggNOG" id="ENOG502ZBU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035969_1_0_11"/>
    <dbReference type="OMA" id="PEWVPWS"/>
    <dbReference type="OrthoDB" id="1601982at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021391">
        <property type="entry name" value="DUF3027"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11228">
        <property type="entry name" value="DUF3027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="35862" checksum="C53C8348AFEB421C" modified="2009-10-13" version="1">MNAATATPARSADSRPRGRQPVLDQVCADAVDLALAAAEDVAGIGEVGRHVGMLAEGDRVVTHLFECKERGYHGWNWAVTLTRAPRTKFVTLDETVLVAGRESVLAPDWVPWSERLRPGDLGPGDLLPIAEDDARLVPAYTGQDEERPQIYREITRDSLPFIAYQLGLGRPRVLSREGREEAAERWHEGEFGPHSPMAQAAPARCSGCGFLAPLAGMLGQGFGVCTNEIAPSDGRVVSLDFGCGAHSEAAVVPAAHPTSEPVVDEYNYDTVTFGERVVLPAGEASQAAEAAAAAVVAAVPADEVTGSGDSGESVESGEPTADGIAGTGSVVGEAAVEEPADES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHI8</accession>
    <name>C7QHI8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0172"/>
    <dbReference type="EnsemblBacteria" id="ACU69127">
        <property type="protein sequence ID" value="ACU69127"/>
        <property type="gene ID" value="Caci_0172"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0172"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="HFMEEAQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="322" mass="34749" checksum="302E14B4F5701FF7" modified="2009-10-13" version="1">MPAIEVRGLRKAYGDVTAVEDVSFEVAEGEIFGILGPNGAGKTTTVECVSGLRTPDAGEVRVLGLDPRRDREDVRQVLGVQLQESQLPGKIHVREALELYASFYRDPADVDRLLAQWELTEKAGARFGKLSGGQKQRLAVALAMVGKPRVVVLDELTTGLDPHARRTAWEMVQAVRDSGVTVLLVTHFMEEAERLCDRVAIIDAGRVVALDTPAAMAARGPAAGQRMRFRPSAPVEDADLLALPEVRSVERHGAHLEVSGTSEVIGAVTAYLARRQIIAAELRVEQSSLDDAFIALTTHATTTTHAAQTMQTAQTAQTAKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHM4</accession>
    <name>C7QHM4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786342.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2130"/>
    <dbReference type="EnsemblBacteria" id="ACU71049">
        <property type="protein sequence ID" value="ACU71049"/>
        <property type="gene ID" value="Caci_2130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2130"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136818_0_0_11"/>
    <dbReference type="OMA" id="AWFEGRY"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="175" mass="19097" checksum="C60DB0D336DD7590" modified="2009-10-13" version="1">MPVHNSHCSYCGTAYVPESAWPRVCANCGETTWLNPLPVALVMMPIIGEDGRTGLLTVRRGIEPQLGEIGLPGGFIEEGESWQQGAVRELWEETGLRADVAEVELADVLSAPSHVILLFGRVKPRPVEDLAELTAERVRTLSNGETLELVVVDHAQPLAFPLHTEMSDRFFAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS8</accession>
    <name>C7QIS8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Histidinol-phosphatase</fullName>
            <shortName evidence="7">HolPase</shortName>
            <ecNumber evidence="4 7">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4 7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8155"/>
    <dbReference type="EnsemblBacteria" id="ACU76978">
        <property type="protein sequence ID" value="ACU76978"/>
        <property type="gene ID" value="Caci_8155"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8155"/>
    <dbReference type="eggNOG" id="COG1387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054611_3_0_11"/>
    <dbReference type="OMA" id="ICFTEHF"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="PTHR21039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="8">
        <location>
            <begin position="5"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="31964" checksum="486640A7F08F333E" modified="2009-10-13" version="1">MLPPDNHVHSEYSWDALAGSMERTCERAVEIGLPSIAFTEHADFSISEMTPESFFPDQWKPYVELVDGRSILTPPRIDLTGYLETLERCRDRFPTLRVLSGVELSEAHWFPEETADLLKRGGFQRILASLHTASARDEDYADIGVSIKRADPSAQYRGYLAEAVRLIEEYDGFEVLTHIDYPVRYWPHEKTPFDLLAFEDDIRLVLRTLARADKLMEFNTRIPLDPRVVGWWRQEGGKGVSFASDAHVPDAVGRGFQEAAEVARAAGFKPGADLFDFWVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIX3</accession>
    <name>C7QIX3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796748.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8200"/>
    <dbReference type="EnsemblBacteria" id="ACU77023">
        <property type="protein sequence ID" value="ACU77023"/>
        <property type="gene ID" value="Caci_8200"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8200"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="WENDQFI"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="27094" checksum="B8C3CB8F02DD823D" modified="2009-10-13" version="1">MRVLITGLGRRRSRTLSGGLAALGFDVLDAADVTGAGPLRRLPDVVLLECGIVDREVLAFCRRLRTELQAPIIAVTHRVDMGAWLRGHDNGIDDYVVQPFGLQELAARLRLAVAPPRPPLTPGPPRRIVAGPLVVAEDSRTVTVHGQRVALRPKEYQLLVVLARQAGTVLARDQLISRLWPAGWDGAERSLEVHIASLRSKLALPGMIATVRGVGYRLVTPESFLRLSSEAVRQLREEAAGRERTVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIY2</accession>
    <name>C7QIY2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796757.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8209"/>
    <dbReference type="EnsemblBacteria" id="ACU77032">
        <property type="protein sequence ID" value="ACU77032"/>
        <property type="gene ID" value="Caci_8209"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8209"/>
    <dbReference type="eggNOG" id="COG4961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1515250_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Tad" evidence="2">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="19413" checksum="E6003A2590028FC1" modified="2009-10-13" version="1" precursor="true">MQRRLKTPRAHPRRSLRRALRDDRGSLAMAVVIWAPVVVLLMAFVVDVGLLISDRTQASDYADQAARRVAQDIDQGWLKTHNVRGPNGEDPGIKVNVDPDTGDCVPDAEQYLLDNQITDTTITSCQVTGNPTEVDLYVNPRITVTLQMQYKPLFVGFALKGDSTVTGTGSATPVIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ21</accession>
    <name>C7QJ21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_0208</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784458.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0208"/>
    <dbReference type="EnsemblBacteria" id="ACU69163">
        <property type="protein sequence ID" value="ACU69163"/>
        <property type="gene ID" value="Caci_0208"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0208"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_11"/>
    <dbReference type="OMA" id="FTRTEFA"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="13"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="138"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU69163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="26471" checksum="08FA3994588C03A4" modified="2009-10-13" version="1">MDTRGSLDREPRSLLVVDDDTEIRDAIARAFRLQGYRVRTASGGLAALEQVAADPPDAIVLDVMMPELDGVEVCRRLRGVGDHTPVLLLTARDAVGDRVAGLDAGADDYLVKPFALAELHARMRALLRRSEYDPVPESERLVFEDLELDPESRLAYRGGRTIELTRTEFALLELLMRNAGRVLPREVISDRIWGYELGPESNSLEVFVSCIRRKTEGGGEPRLVQTVRGFGYTLRVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJB4</accession>
    <name>C7QJB4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome bd ubiquinol oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784551.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0303"/>
    <dbReference type="EnsemblBacteria" id="ACU69256">
        <property type="protein sequence ID" value="ACU69256"/>
        <property type="gene ID" value="Caci_0303"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0303"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_1_1_11"/>
    <dbReference type="OMA" id="FDFRAKV"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="338" mass="34694" checksum="73A80E3CCE22FD4E" modified="2009-10-13" version="1" precursor="true">MTAVDLLLGVIVCALAAYALLAGADFGAGVWDLLARGRHADRERRLIAHALGPVWEANHVWLIFVIVATFSGFPTAFGIIARGLELPLALALAGIVLRGAAYVYRAYGEGAAGPDSLWSRVFAVASSITPFMLGVSGAALATGKITATSGPLTPFDSPFTLVAGVFAVVVTAFLAAVYLCHDAGTDPETEDLVPAFRRRALGAAAVAGVVSMALLPLLYQDAPIVAHRFTERSIPFVAVAVVCGFGSLAVIWKRHYVLARATAATAVIGVLLGWAAAQYPDLAVGAATARGSAAGPANLHALLIAMGFGMVVILPAFYLLLKVFSGPEGAAGGSGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJR5</accession>
    <name>C7QJR5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellulose-binding family II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4289"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73153">
        <property type="protein sequence ID" value="ACU73153"/>
        <property type="gene ID" value="Caci_4289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4289"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030937_0_0_11"/>
    <dbReference type="OMA" id="WWNVHNG"/>
    <dbReference type="OrthoDB" id="620389at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981725" evidence="3">
        <location>
            <begin position="31"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="497"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="5">
        <location>
            <begin position="583"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="699" mass="71872" checksum="0122AF84DBCBA1CD" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK12</accession>
    <name>C7QK12_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4386"/>
    <dbReference type="EnsemblBacteria" id="ACU73250">
        <property type="protein sequence ID" value="ACU73250"/>
        <property type="gene ID" value="Caci_4386"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4386"/>
    <dbReference type="eggNOG" id="ENOG5033A8Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_201963_0_0_11"/>
    <dbReference type="OMA" id="RINTRVN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="51" mass="5791" checksum="4C902A2A1EFAC87B" modified="2009-10-13" version="1">MTYAADQLRDEVAYVAYHFHWALDQILDLEHGDRRAFVTGIAGLNARAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK43</accession>
    <name>C7QK43_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">X-Pro dipeptidyl-peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794846.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75117">
        <property type="protein sequence ID" value="ACU75117"/>
        <property type="gene ID" value="Caci_6263"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6263"/>
    <dbReference type="eggNOG" id="COG2936">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1406506_0_0_11"/>
    <dbReference type="OrthoDB" id="327988at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PepX_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="20644" checksum="A2BE1D8A3B17B47D" modified="2009-10-13" version="1">MTNRHGLRHPHYRYFLLSQGRANTYKGDGVLSASPPAAAALDRFDYDPYAAVPTVDDLDQRSVEVREDVLCFTSAPLTEPVRIAGSVGLVVFVSSSIPGGGITGKLVDVAPDDSTRFITDGIARVPRAREVHELSIDLGAVTAVFAVGHRIRLDVSGGSVPKYAEPGELPAVNRVHHGPETPSRLLLPVVAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKA3</accession>
    <name>C7QKA3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylaspartate mutase E subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794906.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6323"/>
    <dbReference type="EnsemblBacteria" id="ACU75177">
        <property type="protein sequence ID" value="ACU75177"/>
        <property type="gene ID" value="Caci_6323"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6323"/>
    <dbReference type="eggNOG" id="COG4865">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029922_1_0_11"/>
    <dbReference type="OMA" id="HRIPTIA"/>
    <dbReference type="OrthoDB" id="809497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050097">
        <property type="term" value="F:methylaspartate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019670">
        <property type="term" value="P:anaerobic glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006396">
        <property type="entry name" value="Glu_mut_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06368">
        <property type="entry name" value="Met_asp_mut_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001495">
        <property type="entry name" value="Met_asp_mut_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="49428" checksum="C83D82CBE236596F" modified="2009-10-13" version="1" precursor="true">MSAPTIAARAPQTTVTPQSTTSSQTTAASQTAQPRGRFSRFVSQARQQGRLVVQPRMGFGEIAQMRAGLDAVRDSHATAIGTITVDSYTRVNDHESARRALAAGSDLNGFPVVAHGAEQTRRLLAGVSGEQFPVQFRHGSALPYELFQALVEVGADATEGGPVSYCLPYSRVPLARAVAAWAECCRLLADRPEPMHLESFGGCMLGQMCPPSLLIALSVLEGMFFREHGLQSISVSYAQQTHPEQDLEALAALRRLAGERLGGMDWHVVLYTYMGVFPRTAVGAFRILEDSVRLAVRSGTERLIVKTPAEAHRIPTIAENVDALEFSAAVAEDEAGKFGGAPAPFSDTGIYEEARMLIDTTLEYGDTVGSALVTAFARGHLDVPYCLHVDNANRSRADIDSRGRLRWSDPGAMPLRALVGGERTSKTSAFGLIDMLGYNERRFDREQLVGGHLKGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR0</accession>
    <name>C7QKR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796884.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8336"/>
    <dbReference type="EnsemblBacteria" id="ACU77159">
        <property type="protein sequence ID" value="ACU77159"/>
        <property type="gene ID" value="Caci_8336"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8336"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042900_1_1_11"/>
    <dbReference type="OMA" id="PIPTDGY"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016676">
        <property type="entry name" value="P_lipid/glycerol_AcTrfase_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016753">
        <property type="entry name" value="P_lipid/glycerol_ac_tran_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="129"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36405" checksum="35D7E1BBBA1A6C94" modified="2009-10-13" version="1">MASKPETAPEQTSEAGGAEDAGASEASGAPETPGAAATAEASAAAEAAATAEIPEALEPSAGSGGWEQKAAGALAFLRRRVTGDYEVDEFGFDPDLNDNVLMGVLRPLYEKYFRVEVSGIENVPSEGGALIVANHSGTVPVDALMTQVALLDHHPAGRHLRMLAADLVFTLPFVGELSRKMGHTLACNPDAERLLRGGEVVAVFPEGFKGVGKPFSQRYRLQRFGRGGFVSAALRTGVPIIPVSIVGAEEIYPKIADLKPLARLIGLPYFPITPTFPLLGPLGMVPLPTKWHITFGEPIPTSGYDPGAADDPMLVFDLTDQVRETIQDTLYRVLLQRRSVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVF5</accession>
    <name>C7PVF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784606.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0358"/>
    <dbReference type="EnsemblBacteria" id="ACU69311">
        <property type="protein sequence ID" value="ACU69311"/>
        <property type="gene ID" value="Caci_0358"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0358"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_2_0_11"/>
    <dbReference type="OMA" id="AQEAFYA"/>
    <dbReference type="OrthoDB" id="1765806at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="15661" checksum="FB1922D798C498E9" modified="2009-10-13" version="1">MHLMKSTDLALRLLMRLAVVPPDTHPDELPTTRGVAEAMGAASTHMAKVVGKLQHLGLVQARRGRGGGLVLTPAGRVASVGAVVRTFEGSGDLAACVDGEDPCPLNAACRLRSALRAAQEAFYASLDQLTVEDVTAAPTGPLLLSIAMGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH8</accession>
    <name>C7PVH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase zinc-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784629.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0381"/>
    <dbReference type="EnsemblBacteria" id="ACU69334">
        <property type="protein sequence ID" value="ACU69334"/>
        <property type="gene ID" value="Caci_0381"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0381"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OMA" id="EHYNDSW"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="17"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="36322" checksum="18A15FD1FB792E71" modified="2009-10-13" version="1">MTDQTLVQVVLPGKVEPEDLQVQHAAVPQPAVGQVVIAMEATGVSFAEQQMRRGRYFDQPPFPFVPGYDVVGRVYAVGAGVDPGLLGRRVAVLTKVGGWASHVLADARDAVEVPEGLTAEQAETVVVNGITAWQMLHRRARVKAGQTVLVHGVNGGVGSVLAQLAMAAGATVIGTASARHHDALRAAGILPVDYRAGNVPEQVRALAPHGVDAVFDHVGGRSVIDSWHLLAPGGTLVSYGSASTRDDSGWKQWPVLKILARTTLWTLLPNGRSASFFNIWAGKKLNQDRFRARLRADLTEVFAALGRGDIVTTIAARLPLAQAGEAMRLAESGTVAGKIILTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVN0</accession>
    <name>C7PVN0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ATP/GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784681.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0434"/>
    <dbReference type="EnsemblBacteria" id="ACU69386">
        <property type="protein sequence ID" value="ACU69386"/>
        <property type="gene ID" value="Caci_0434"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0434"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_8_11"/>
    <dbReference type="OMA" id="ARAYHAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="713" mass="76266" checksum="1B0976B0233DF1CC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVT1</accession>
    <name>C7PVT1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="15">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">carB</name>
        <name evidence="19" type="ordered locus">Caci_2405</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="15">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="15"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786616.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2405"/>
    <dbReference type="EnsemblBacteria" id="ACU71323">
        <property type="protein sequence ID" value="ACU71323"/>
        <property type="gene ID" value="Caci_2405"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2405"/>
    <dbReference type="eggNOG" id="COG0458">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000513_1_0_11"/>
    <dbReference type="OMA" id="IEPAGIH"/>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 15" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="133"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="677"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="18">
        <location>
            <begin position="950"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="15">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="15">
        <location>
            <begin position="950"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="827"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="841"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACU71323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1099" mass="117518" checksum="28291E0E4240C0CF" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVX1</accession>
    <name>C7PVX1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sensor with HAMP domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2445</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786656.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2445"/>
    <dbReference type="EnsemblBacteria" id="ACU71363">
        <property type="protein sequence ID" value="ACU71363"/>
        <property type="gene ID" value="Caci_2445"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2445"/>
    <dbReference type="eggNOG" id="COG3920">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_286793_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="368"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="680"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="787"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="724"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="836"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="941"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1011"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1031"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1076" mass="111873" checksum="97DA90542B5FFAB8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW14</accession>
    <name>C7PW14_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786699.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2488"/>
    <dbReference type="EnsemblBacteria" id="ACU71406">
        <property type="protein sequence ID" value="ACU71406"/>
        <property type="gene ID" value="Caci_2488"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2488"/>
    <dbReference type="eggNOG" id="COG5516">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087298_3_1_11"/>
    <dbReference type="OMA" id="NRHKVRA"/>
    <dbReference type="OrthoDB" id="1478254at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35525">
        <property type="entry name" value="PTHR35525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
        <property type="entry name" value="ABATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11706">
        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
        <property type="entry name" value="SSF160904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="145"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21544" checksum="638561DA1B59EA2F" modified="2009-10-13" version="1">MARLQGLPPDQARRFRTGRAGLDLAHTGGDGPYAKFELFFVPEDVSRWLEVIADLDGIEADADDVTAARDLRRAIWNTAHRAIAGEQAAEPDRQAINAAAAHPAPVPMLTRDGTAEFHRPITARHVLSMLARDAVDLFASPLAARIRVCSAPDCGLLYVDQSRTGNRQWCSMQRCGTRAKVRAHRERAQTPPSEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW69</accession>
    <name>C7PW69_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulator, Fur family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793046.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4454"/>
    <dbReference type="EnsemblBacteria" id="ACU73317">
        <property type="protein sequence ID" value="ACU73317"/>
        <property type="gene ID" value="Caci_4454"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4454"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_4_0_11"/>
    <dbReference type="OMA" id="DHPHADT"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="15235" checksum="5C08D811509E6A84" modified="2009-10-13" version="1">MTASHPPTAAEELRGAGLRVTAARVALLETVRGGDHLDADAIASGVRARVGHVSLQAVYEALHALTAARLVRRIEPAGSPARYEGRVGDNHHHLVCRSCGTVVDVDCAVGAAPCLDPVDDHGFTIDEAEVVYWGLCPGCAVPAGPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWF9</accession>
    <name>C7PWF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794968.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6385"/>
    <dbReference type="EnsemblBacteria" id="ACU75239">
        <property type="protein sequence ID" value="ACU75239"/>
        <property type="gene ID" value="Caci_6385"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6385"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082704_0_0_11"/>
    <dbReference type="OMA" id="RYHEPLS"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27889" checksum="253357D212754E9E" modified="2009-10-13" version="1">MNEAVERVVAYLYDQYDQPITLADMADVAILSQFHFARTFREVTGVSPGRFLSAIRLQRAKTLLTTTELTVTDISYMVGYNSLGTFTSRFTKSVGVTPIQYRSFAQADLAAGLGGAGRPGEDPAAFGAMAGWMTLPPAAEVRLMYIGVFDGPILQHLPVSCTMVENETAFQLDSVPEGEWYVFAAAVNPDEPPVDEYGSRVARLVAREGPVKCVRGQTTMLDLAMRPCRPTDPPMLLALPVVLDCSRVRQPMATSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWW9</accession>
    <name>C7PWW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8403"/>
    <dbReference type="EnsemblBacteria" id="ACU77226">
        <property type="protein sequence ID" value="ACU77226"/>
        <property type="gene ID" value="Caci_8403"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8403"/>
    <dbReference type="eggNOG" id="COG5500">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111152_0_2_11"/>
    <dbReference type="OMA" id="AMQRINV"/>
    <dbReference type="OrthoDB" id="2075110at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19747" checksum="BAC2376343EAC244" modified="2009-10-13" version="1" precursor="true">MKTRVNGSGVLAAATVVTGLIAGVYYAFACSVMLGLGASGDRTFIEAMQNINKKIENPVFFLTFFGALILPAWALRTYRQDRTLRLWIAAGLVLYTIGLLTTMAVNIPLNNQLAAAGAPARIADPAAVRARFEDTWNMWNIARALLSTGAAACLARALLLAGWRGETQRAEAEAPTASRMWSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX63</accession>
    <name>C7PX63_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="3 9 10">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_0462</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9 10">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="3 9 10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784709.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0462"/>
    <dbReference type="CAZy" id="CBM2">
        <property type="family name" value="Carbohydrate-Binding Module Family 2"/>
    </dbReference>
    <dbReference type="CAZy" id="GH11">
        <property type="family name" value="Glycoside Hydrolase Family 11"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69414">
        <property type="protein sequence ID" value="ACU69414"/>
        <property type="gene ID" value="Caci_0462"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0462"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_1_0_11"/>
    <dbReference type="OrthoDB" id="1121261at2"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 10" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981330" description="Endo-1,4-beta-xylanase" evidence="12">
        <location>
            <begin position="40"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="14">
        <location>
            <begin position="42"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="13">
        <location>
            <begin position="245"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU69414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="337" mass="34535" checksum="4745DE0B0999E623" modified="2009-10-13" version="1" precursor="true">MPGNSRLPGARRSRRLRMFIGVVLALFLGAMLPSVPASAATSICSNQTGTNSGYYYQMWSSGQGSACISLNSGNSYSSTWSGIGDFVAGVGWNPGDKSTKSFTGSLNANGGTSLVSLYGWSTSPLVEYYVMENYVGSPPTAGTYMGQVTSDGGTFNIYEHQQVNQPSIQGTATFEQYLAIRTSPVSSGTITMSNYINAWSSHGMNLGTLNYQILATEAWGGGSGSSNVSVSSGGGGGGGGGGGGGGGGGGSCTATLSAGSQGSNWYNLNVAVTGSSNWTVTMNMASPAVVYNTWNVSATWPSQYVMVAKPNGSGNNFGVTISPNGQWTWPSVSCSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA0</accession>
    <name>C7PXA0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69451">
        <property type="protein sequence ID" value="ACU69451"/>
        <property type="gene ID" value="Caci_0504"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0504"/>
    <dbReference type="HOGENOM" id="CLU_3364020_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="35" mass="3716" checksum="2AD42B4D29525EF9" modified="2009-10-13" version="1">MLLSPLARYLVVAGVDAAATTVTVKGVDYFFDLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXF9</accession>
    <name>C7PXF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786705.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2494"/>
    <dbReference type="EnsemblBacteria" id="ACU71412">
        <property type="protein sequence ID" value="ACU71412"/>
        <property type="gene ID" value="Caci_2494"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2494"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_1_0_11"/>
    <dbReference type="OMA" id="FGAPMQR"/>
    <dbReference type="OrthoDB" id="1374795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="22035" checksum="84AD3805C47DB5AA" modified="2009-10-13" version="1">MTAKTPAPITLTGSHIRLEPLSRSHLPDLFAAGGNDDAVWQWQGGPTPRTEQELGAKLDKIVGNASYVAFAVILLSTGKAIGWTTFSDISAVDERLEIGWTWYGSAYWRSAVNTEAKLLLLVHAFEDLGMGRVQWKTDHMNQRSQNAIARLGAQREGVLRRHRMRPDGTFRDSVYFSMLAEEWPAAKQRLTERLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXI5</accession>
    <name>C7PXI5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786731.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2520"/>
    <dbReference type="EnsemblBacteria" id="ACU71438">
        <property type="protein sequence ID" value="ACU71438"/>
        <property type="gene ID" value="Caci_2520"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2520"/>
    <dbReference type="HOGENOM" id="CLU_926504_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="300" mass="32340" checksum="23476441D37756C6" modified="2009-10-13" version="1">MEDEDDWRTHVARANALIQQRRPHEAIPLARQAVALAPDEPDARLALADALLAVWPRRTSCVAAAFAEVDEAELLGVDAEDLAVRRSKSKGFGLYVVAWTTFALFTLYGINGNGGAIGRAIAWPGMFAFFCVTPIVTARLGGQRFGHRMKTRRRIHRKRLATDAQVSQRAPAAAAVFTFLVLPSAGTLPPVIDGDAAWLWLFWLMLGGIPLAGAAAWIGIDRWLRPGTVLRTLRHDAFVADSVCVTFVLAMTAPALVLGGVRSSGILFSLFLLDLAWLAIGGLSGAKVSSHRKKAAIDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN9</accession>
    <name>C7PXN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786785.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2574"/>
    <dbReference type="EnsemblBacteria" id="ACU71492">
        <property type="protein sequence ID" value="ACU71492"/>
        <property type="gene ID" value="Caci_2574"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2574"/>
    <dbReference type="eggNOG" id="COG4667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_920802_0_0_11"/>
    <dbReference type="OMA" id="YPHRSIN"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07208">
        <property type="entry name" value="Pat_hypo_Ecoli_yjju_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037483">
        <property type="entry name" value="YjjU-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="30"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="63"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="33411" checksum="D9CE8792C1DAD340" modified="2009-10-13" version="1">MKVTALELLRMRNQQGSEPGRRRDDARLALVIEGGSSRGAYSAGMTGAIEQLGILPLFDAVYGSSAGALNGAWMLCGKAESTMHAWWTPEIMRGTIDPKRALRRRPVVDTHYLVHTVYTDIMPMGFEQILASPIEFHPMATDAETGESVDLHPFLHDTPSLQAAFRASTAMPLLTGTPIQIDGRRFVDAGVSEAVPVRTALAQGATHVIALRTRRADERTTPPARIERIVLTRWFTRNAPGALQPWMNRTAIRAQEERVLAEHPGVLQIRPPVGSGDIGRTEVGGSALRAAVDIGRQAAFTALTPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXS1</accession>
    <name>C7PXS1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CE2_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786817.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2607"/>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71524">
        <property type="protein sequence ID" value="ACU71524"/>
        <property type="gene ID" value="Caci_2607"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2607"/>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023231_2_0_11"/>
    <dbReference type="OMA" id="VNITEYA"/>
    <dbReference type="OrthoDB" id="956236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040794">
        <property type="entry name" value="CE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17996">
        <property type="entry name" value="CE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982295" description="CE2_N domain-containing protein" evidence="1">
        <location>
            <begin position="45"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="CE2_N" evidence="2">
        <location>
            <begin position="660"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="755" mass="77610" checksum="A158E640D196F937" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV1</accession>
    <name>C7PXV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793140.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4549"/>
    <dbReference type="EnsemblBacteria" id="ACU73411">
        <property type="protein sequence ID" value="ACU73411"/>
        <property type="gene ID" value="Caci_4549"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4549"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069623_3_0_11"/>
    <dbReference type="OMA" id="TTVFGWS"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="138"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="258" mass="27074" checksum="FF643716DFAF0948" modified="2009-10-13" version="1">MKPTEAAIGAPCWAELGTADVPESGEFYSTLFGWTVTTDPRTEAGGYTIAALHDVPVAALSPLYAPGQPVAWTVSFAVLDADATAGRAAEEGGAVLMAPMDIFDSGRFAVLRDPAGAMFTVWQPRAFQGFGLWDEPAAACWVELATRDVPAASAFYQSLLGWSVSSDAYSHLSAAGREFGGVQDMNATGVPEDVAAHWLLYFKTQDTAATTKQAAELGAQILAGPFRLPGTGYVATLRDPQGAVFALYEPDGEDAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC6</accession>
    <name>C7PYC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6570"/>
    <dbReference type="EnsemblBacteria" id="ACU75416">
        <property type="protein sequence ID" value="ACU75416"/>
        <property type="gene ID" value="Caci_6570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6570"/>
    <dbReference type="HOGENOM" id="CLU_2380945_0_0_11"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="94" mass="10577" checksum="9C07C36128F133D9" modified="2009-10-13" version="1">MTAIDEHPSPDQGRRHLFARWVGRLIGSPHQSGFRQVYVVENQDWLAPKSNLSDQEAYDAIVDLYESVTDEQYGVAIAELKKAQAPESDDSPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYI3</accession>
    <name>C7PYI3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797030.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8482"/>
    <dbReference type="EnsemblBacteria" id="ACU77305">
        <property type="protein sequence ID" value="ACU77305"/>
        <property type="gene ID" value="Caci_8482"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8482"/>
    <dbReference type="HOGENOM" id="CLU_1198029_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24310" checksum="A78CA5D5930582C6" modified="2009-10-13" version="1">MTSYYGEYVPPPPPPPPKVTSTTSTSSSADCSYTLNVTVGNPPGSSDRHDDTTAPATGKGFAGYTWNQAITAIVGGCGDGSYGDLPPEGTWAKPPTLETAHYAILTIRTMLDNYVTAVNAARDSILKSWKGPAADAFKTTLKSFTDYVTALSAEMHKYNEAGPNNLLHIAHMNQAMSDAASFIWAGSTYADGHDRKTPVTLAGDLSYTGTMLGAGEAMVQAFDAALTALNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ37</accession>
    <name>C7PZ37_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784888.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0657"/>
    <dbReference type="EnsemblBacteria" id="ACU69593">
        <property type="protein sequence ID" value="ACU69593"/>
        <property type="gene ID" value="Caci_0657"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0657"/>
    <dbReference type="HOGENOM" id="CLU_1988617_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="13179" checksum="F63CD1E4B8EC42B9" modified="2009-10-13" version="1">MGSLLTGVPIGLRLPAGLGGDAAPYVPSAPVQIGTSGQHRGVGEAGSWQALLVMFAVVLILGTAVLMFAVRQRTRVLRRRRVRRMGEAAALMAAMAEGDSHHPHPARATAHHTRHTGPPSPERVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ40</accession>
    <name>C7PZ40_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0660"/>
    <dbReference type="EnsemblBacteria" id="ACU69596">
        <property type="protein sequence ID" value="ACU69596"/>
        <property type="gene ID" value="Caci_0660"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0660"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276186_0_0_11"/>
    <dbReference type="OMA" id="WIQISAS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="638"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1153" mass="113373" checksum="ADC7784E439FF71D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ82</accession>
    <name>C7PZ82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2622"/>
    <dbReference type="EnsemblBacteria" id="ACU71539">
        <property type="protein sequence ID" value="ACU71539"/>
        <property type="gene ID" value="Caci_2622"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2622"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_9_1_11"/>
    <dbReference type="OMA" id="RNWPYSI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982350" evidence="1">
        <location>
            <begin position="26"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="46249" checksum="588AB24F8EDFE645" modified="2009-10-13" version="1" precursor="true">MNATPLNAAASRRSFLLGGLSIVGAAALSGCSVTGTSQKKGSAGSGSGTINVLFMQQAGYSTDDVTKMTAAFTKQYPDIKVNPTYVAYEALHDKIVTAAAAGTYDVVLIDVIWPAEFGKKNIVADVTSRYPADWKDTMLGGALLTADYDGKQYGVPWGMDTKFFYYNKALLAKAGVDASTLGTWSGVLQAAKALKQAKVVEYPLAWSWSQAEAIMCDYTQLVGAFGGSFTDSAGNLTLNKGGAVDALAWMRQSIVDGLTNPSSTTFLEADVEKTMNNGQAAFGLNWTYYLGSSNDPKNSQVPGQIVVAQTPAGPSGKRPGVNGAMALSVSTGSKNQDAAWKYISWIAGEDQVDQFAKDEMPIWKKSFTTPSVVSSAPDMFAVAAKQLDDLVVRPQFVNYNAVSQVIQVELQNALLGKKPAQQALDDAVKAAQPLMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZB2</accession>
    <name>C7PZB2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71569">
        <property type="protein sequence ID" value="ACU71569"/>
        <property type="gene ID" value="Caci_2653"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2653"/>
    <dbReference type="eggNOG" id="COG4891">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069867_4_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="154" mass="16986" checksum="87730625CD2F6397" modified="2009-10-13" version="1">MKSVGRTTAVALDIEAPPDRIWSVLADTRSYADWNDHLRPDRPTESTAGMLRAGAIVVLRLSASQRRFIALRSTVTVAHPGYEARWVGRCMAPWLLSWEHSFDLTDGGDGTTRVLQTLTWRGLLAPVAGSSRWAAGFDHDMDALGEALRKRVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZH7</accession>
    <name>C7PZH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71634">
        <property type="protein sequence ID" value="ACU71634"/>
        <property type="gene ID" value="Caci_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2719"/>
    <dbReference type="HOGENOM" id="CLU_1616021_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="164" mass="15603" checksum="1A507053570D5633" modified="2009-10-13" version="1" precursor="true">MSRRSVLCGGASRFGSASRFGEASRFGGASRFSGASEFGGASFSGGASRFGGASRFGGASRFGGASRFSGASEFGEVSLFGGRLVGGASTAGEASVSGGSLFGGANSATEASLFGKSLIGGASTVGGASFSGESLFGGASTVGKASISGARRRLPAACGEGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZS4</accession>
    <name>C7PZS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine pyrophosphate protein TPP binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4728</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793318.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4728"/>
    <dbReference type="EnsemblBacteria" id="ACU73589">
        <property type="protein sequence ID" value="ACU73589"/>
        <property type="gene ID" value="Caci_4728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4728"/>
    <dbReference type="eggNOG" id="COG3960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_11"/>
    <dbReference type="OMA" id="MIEREAN"/>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009028">
        <property type="term" value="F:tartronate-semialdehyde synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009436">
        <property type="term" value="P:glyoxylate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006397">
        <property type="entry name" value="Glyox_carbo_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF14">
        <property type="entry name" value="PTHR18968:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="3">
        <location>
            <begin position="191"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="389"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="572" mass="61934" checksum="9591BBCCFDB73955" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZU4</accession>
    <name>C7PZU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793338.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4748"/>
    <dbReference type="EnsemblBacteria" id="ACU73609">
        <property type="protein sequence ID" value="ACU73609"/>
        <property type="gene ID" value="Caci_4748"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4748"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_2_1_11"/>
    <dbReference type="OMA" id="IGMHRVA"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="145" mass="15652" checksum="D0F0592E7150362D" modified="2009-10-13" version="1">MDHVSINVEDLDAAKRFFFALGMEFAGEAKVGGPMVGRVIGLQDPMSDVVFVRTPDGHSQIELVKHLAAPDPEGPAAPASNRLGLIHVAFQVEDLRDLLAELHALGYDPLGTVENYEDVYLLCFLRGPEGIIVELAEDISAKQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0C2</accession>
    <name>C7Q0C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797179.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8639"/>
    <dbReference type="EnsemblBacteria" id="ACU77455">
        <property type="protein sequence ID" value="ACU77455"/>
        <property type="gene ID" value="Caci_8639"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8639"/>
    <dbReference type="eggNOG" id="ENOG50336D6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135051_0_0_11"/>
    <dbReference type="OMA" id="MAFAWSA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="170" mass="18501" checksum="7C703389E4C78D57" modified="2009-10-13" version="1">MIATNWAMRQLAGPDPLALADPQTVTPAAREVLASGWMTEPSGANVLVELRAGYHGPDFRPGDLTGYEAAVNGRGVADDDITVEGDERERALLVRAVSYAVQALAEARELPDRDRLTAVVSLSMSGDDVPVPTAKVTFYVQRDDERPYLRDVEEYAFESLLVFDYTAAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0E8</accession>
    <name>C7Q0E8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797205.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8666"/>
    <dbReference type="EnsemblBacteria" id="ACU77481">
        <property type="protein sequence ID" value="ACU77481"/>
        <property type="gene ID" value="Caci_8666"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8666"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_1_11"/>
    <dbReference type="OMA" id="PQILAMY"/>
    <dbReference type="OrthoDB" id="1469807at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="105"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="404" mass="44254" checksum="42F53F23B0DA544A" modified="2009-10-13" version="1">MTAPAIEDLLRELTPQVLGALVRRYGRFEGCEDAVQEAVLAASVQWPDEGVPENPRGWLTTVASRRLIDQVRSDSARREREEQVWASDVVPDEVPDTDDTLVLLFLCCHPTLTAASQTALTLRAVGGLTTAEIARAFLVPEATLAARVSRAKQRIKTAGSSFELPAGPEREERLQVVLHVLYLIFNEGYTASSGTELDRVDLATEAIRLTRMVYAQLPDDGEVAGLLALMLLTHSRREARTTAQGDLIPLDEQDRAKWDAELIAEGLELAKTSLAGTELGPYQLQAAIAATHAVATDAADTDWRQIHTLYLVLERIAPNPMVTLNRAVALAEIEGPQAGLAVLATLDSDERMAKHHRLLSVRAHLLEMAGDTDAAYENYRRAAKATASLAEQRHLESRAKKLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0F7</accession>
    <name>C7Q0F7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797214.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8675"/>
    <dbReference type="EnsemblBacteria" id="ACU77490">
        <property type="protein sequence ID" value="ACU77490"/>
        <property type="gene ID" value="Caci_8675"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8675"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_22_0_11"/>
    <dbReference type="OMA" id="TFEPHEV"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014303">
        <property type="entry name" value="RNA_pol_sigma-70_ECF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02957">
        <property type="entry name" value="SigX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="7"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="106"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="306" mass="33585" checksum="C2F716C4D9128B70" modified="2009-10-13" version="1">MTRDEEFEDLRPLLFSIAYRILGSVAEAEDAVQDTWLRWQGTSTQPASAKAFLSAVVTRISIDVLRSARVRREEYVGPWMPEPLLTDPYEDPERAAELADSLSTAALLLLERLSPLERAVFVLREVFGFGFPEVASAVGRSEAACRQLAVRARRHMNDGRPRFEADRHEREELAERFFDAFREGDVAGLRELLAADVCLVGDSGGKAPLVAQEAYGAEAVAALVVFVAERFDRIGVRLESHALNGQPGAIFHAPDGKVLSVMTLDVAEGRIQAIHALVNPDKLAHMGPVADIWALSRAAMEGDPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0G1</accession>
    <name>C7Q0G1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
            <ecNumber evidence="9">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8679"/>
    <dbReference type="EnsemblBacteria" id="ACU77494">
        <property type="protein sequence ID" value="ACU77494"/>
        <property type="gene ID" value="Caci_8679"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8679"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_11"/>
    <dbReference type="OMA" id="VMVVFAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
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            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="56"/>
            <end position="482"/>
        </location>
    </feature>
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        <location>
            <begin position="499"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="533" mass="56739" checksum="11C7BA09A43979EA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q107</accession>
    <name>C7Q107_CATAD</name>
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        <submittedName>
            <fullName evidence="7">Molybdopterin oxidoreductase</fullName>
        </submittedName>
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        <name evidence="7" type="ordered locus">Caci_2769</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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            <taxon>Actinobacteria</taxon>
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        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
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        <property type="protein sequence ID" value="ACU71682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
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    <dbReference type="STRING" id="479433.Caci_2769"/>
    <dbReference type="EnsemblBacteria" id="ACU71682">
        <property type="protein sequence ID" value="ACU71682"/>
        <property type="gene ID" value="Caci_2769"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2769"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000422_13_3_11"/>
    <dbReference type="OMA" id="LEPDEWH"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF18364"/>
        </source>
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            <dbReference type="EMBL" id="ACU71682.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="836" mass="88606" checksum="CA335042BA69D47D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q113</accession>
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        <submittedName>
            <fullName evidence="4">Extracellular solute-binding protein family 3</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ordered locus">Caci_2775</name>
    </gene>
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        <lineage>
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        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2775"/>
    <dbReference type="EnsemblBacteria" id="ACU71688">
        <property type="protein sequence ID" value="ACU71688"/>
        <property type="gene ID" value="Caci_2775"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_3_11"/>
    <dbReference type="OMA" id="PAYAPWF"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980521" evidence="2">
        <location>
            <begin position="34"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="58"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="30220" checksum="197430F8BD42D599" modified="2009-10-13" version="1" precursor="true">MFRPTLRTALALGAGAALALAAAACSPASSKPAATGTSTGSGAPDCSPATLHLVAKGTLTIATDTPAYAPWFDNNTPSDGKGFESAVAYAVAAKLGFTQSQVKWVTEPFDNSYAPGPKNFDFDLNQISITDERKKAVDFSSGYYTVTQGVITLKTSKYAGATSLAGLKPAKIGVQVGTTSMQAVQGKIAPSQQPAVFTTTDDEVNALKNGQIDALVTDLPTVFYLTASSIDNGKVVGQFDYTDSGVEQFGALFAKGNPLVGCVDGAIDQLKSGGELAALTTQWLSTSANAPKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q142</accession>
    <name>C7Q142_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
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            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787010.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2806"/>
    <dbReference type="EnsemblBacteria" id="ACU71717">
        <property type="protein sequence ID" value="ACU71717"/>
        <property type="gene ID" value="Caci_2806"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_14_1_11"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="5"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="12272" checksum="0038FF10EA684D5E" modified="2009-10-13" version="1">MSTLVTAELFARPGRGDDVAQLLLDVLGESLKHEGCEQIRILRDQNDADHVTGLTQWTEPHNYTDYLAWRTEHGFTATFEAMLTRPLVIHYYDEIYRGQGIAAHVNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K9</accession>
    <name>C7Q1K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793467.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4878"/>
    <dbReference type="EnsemblBacteria" id="ACU73738">
        <property type="protein sequence ID" value="ACU73738"/>
        <property type="gene ID" value="Caci_4878"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4878"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_7_4_11"/>
    <dbReference type="OMA" id="QRINAEF"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12735" checksum="97BA2997F84EDB92" modified="2009-10-13" version="1">MPGSTRSTPADRLDDDDYPAYTMGRAAEMIGATPAFLRALGEAKLIVPLRSDGGHRRYSRYQLRIAARARELVDTGTPVDAACRIIILEDQLEEAQRLNAELRRHAAENTAPAEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M7</accession>
    <name>C7Q2M7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="13" type="ordered locus">Caci_0937</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785164.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0937"/>
    <dbReference type="EnsemblBacteria" id="ACU69869">
        <property type="protein sequence ID" value="ACU69869"/>
        <property type="gene ID" value="Caci_0937"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0937"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_0_0_11"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="223"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="292" mass="31802" checksum="9E54827CE19E87A3" modified="2009-10-13" version="1">MGQKVNPHGFRLGITTDFKSRWYADKLYKDYVKEDVAIRRLMTEGMDRAGISKVEIERTRDRVRVDIHTARPGIVIGRRGAEADRIRGKLEKLTAKQVQLNILEVRNPESDAQLVAQGIAEQLAQRVAFRRAMRKAIQSSMKAGVKGIKVQVSGRLGGAEMSRSEQYREGRVPLHTLRANIDYGFYEAKTTFGRIGVKVWIYKGDVTSLSAQRALNAAEARAGRPARDGDRRGGGRDGGGRPPRRDGGGGRGPRRDGGGGQQSQAPAQAPAATEAPAPASAETVSDSKSKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q333</accession>
    <name>C7Q333_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4909</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4909"/>
    <dbReference type="EnsemblBacteria" id="ACU73769">
        <property type="protein sequence ID" value="ACU73769"/>
        <property type="gene ID" value="Caci_4909"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4909"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_3_11"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="313" mass="33600" checksum="FD3BE9584BD30679" modified="2009-10-13" version="1">MDLNLLTALDALLAENSVAAAADRLHLSPPAMSRTLARIRKATGDDILVRTGRAMTPTPHALALREETRDLVARATALLTPVTELDLPNLERGFTLRCHDALVAALAPALIEAVAETAPNVSIRFLAEPSADAADLARGQTDLEVGAAAPQRPEIAAHTIGTDRMVAVMRPDHPLATGPLTPQRFAEADHLTISRRGRLTGPIDEALADLGLHRRVRAALPTTSTALELTARTTLITTVAEQVCRPAWTNLGLRARPLPFTLPAVPVIVAWHHRYDTDPAHSWLRTHLLAVLKTILTAPEPNPTPMTDDAGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q342</accession>
    <name>C7Q342_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793507.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4918"/>
    <dbReference type="EnsemblBacteria" id="ACU73778">
        <property type="protein sequence ID" value="ACU73778"/>
        <property type="gene ID" value="Caci_4918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4918"/>
    <dbReference type="eggNOG" id="COG3618">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_3_0_11"/>
    <dbReference type="OMA" id="ETCIEAF"/>
    <dbReference type="OrthoDB" id="1979322at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="4"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="30992" checksum="189142976A375184" modified="2009-10-13" version="1">MPRIDAHHHLWKLADRPQAWLDGPGTAAIRRDFTLADLRAETTAAKIDHTILIQVLPDLDETWDFLALAAGSDLVAGVVGWADLTAPVIPDVLAALRGVRGGDKLLGVRHLVQGEPDPAWLNRPDVRRGLKALAEADLVYDLLTVPHQLPAAIDTVRALPELTFVLDHLSKPPIASGDTEPWASRIRELAAEPNVFCKLSGMVTEADRDTWRIDDLRPYADTVLEAFGPSRVMFGSDWPVCLLAATYDEACHVAESLTAHLGSEERADVFGGTAVRAYGLAAEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G2</accession>
    <name>C7Q3G2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TadE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6889"/>
    <dbReference type="EnsemblBacteria" id="ACU75727">
        <property type="protein sequence ID" value="ACU75727"/>
        <property type="gene ID" value="Caci_6889"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6889"/>
    <dbReference type="eggNOG" id="COG4961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128792_0_1_11"/>
    <dbReference type="OMA" id="IQKDHGT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="15279" checksum="0EFF8E848C96D0B1" modified="2009-10-13" version="1">MADAAASRRYRRCGEADSGFATLETVIVTPILVLVLLVAVAAGRLESARLDVDTAAGAAARAASLTRGPAGAAAAAKAEAARSLASAGVSCPQPKVVVDTAVFRPGGVVKVTVTCRADLGDLASVGLLPLRTSITKSSTSPIDQYRQATAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3J5</accession>
    <name>C7Q3J5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bacHORMA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795488.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6927"/>
    <dbReference type="EnsemblBacteria" id="ACU75760">
        <property type="protein sequence ID" value="ACU75760"/>
        <property type="gene ID" value="Caci_6927"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6927"/>
    <dbReference type="eggNOG" id="ENOG50307TE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110705_0_0_11"/>
    <dbReference type="OrthoDB" id="1325424at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040649">
        <property type="entry name" value="Bact_HORMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18173">
        <property type="entry name" value="bacHORMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="SSF56019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bacHORMA_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="18670" checksum="948E31E8138C86CD" modified="2009-10-13" version="1">MATSVRVNTTTHAATHVATNMIRSLKQIIRAAGLDPAGLLGQWALLESGVSTWLQSGHLTTLVMEVFDPSDRTVTSLVGRFDFTIEYDYGADSDGDLWLDPDVIDYVIRKNGAYPSQCEYDFTVVNKPGRPAVPGWGKGQLRSSDHLTRRTAGTAITGGTIGASISYYTRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R1</accession>
    <name>C7Q3R1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797393.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8856"/>
    <dbReference type="EnsemblBacteria" id="ACU77669">
        <property type="protein sequence ID" value="ACU77669"/>
        <property type="gene ID" value="Caci_8856"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8856"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_11"/>
    <dbReference type="OMA" id="WRSVAFS"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="28798" checksum="2AF14CD4BAACFCBC" modified="2009-10-13" version="1">MSEVSEKDYNGVLLRRHPAFGNGVVAEIVLNRGAAMNAISTGMAAAIRDVGTELAEDPAVRAVVVSAVPPVVEGKNHAFCVGVDLKERDRMTDAELVATRPAFRRTWGTFGSLPMPVVAAVSGYALGGGCELALACDLIVADDGAVFGLPEVSVGVIPGGGGTQTLVRRVGMNRAADLIFTARRVDADEADRFGMIDRRVAGSSTARGAALELAQQIAKNSPIGVRNAKHALKVGADLPLAAGLDVEDGAWRATAFSADRAEGVRAFVEKRAPIWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3V1</accession>
    <name>C7Q3V1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epoxide hydrolase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8896</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797433.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8896"/>
    <dbReference type="EnsemblBacteria" id="ACU77709">
        <property type="protein sequence ID" value="ACU77709"/>
        <property type="gene ID" value="Caci_8896"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8896"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_1_11"/>
    <dbReference type="OMA" id="NIDPACK"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033961">
        <property type="term" value="F:cis-stilbene-oxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EHN" evidence="4">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="40998" checksum="6089BAD240B79C60" modified="2009-10-13" version="1">MTQQQSTAIRPYRVEIPQADLDDLRRRLEQTRWTSVLDGADGEYGTALSRVRRLAEYWRDGFDWRAFEARLNAHPQFLTEIDGQDIHFLHVKADAPNGTALLLTHGWPGSQAEYLDVIEPLTAAGYDLVIPSIPGYGFAGPTTAQGWNLHHTARAWVELMARLGYRRYGAVGNDGGSMISPEVGRLDPEHCVGVHVTQLFSFPSGDPAELTDMTPEEKQAIETLQWFWENMGSFNQVQTQQPQTLAHALSDSPVGLLGWNIQLLPENLDDDFILANVATYWFTGTAGSALRFYREMALDTERPEGPTTVPTALAGSANDFFGIRRFAERDHANIVRWNVYETPGHYAAHQAPEVLVRDVVEFFGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4F1</accession>
    <name>C7Q4F1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787213.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3011"/>
    <dbReference type="EnsemblBacteria" id="ACU71920">
        <property type="protein sequence ID" value="ACU71920"/>
        <property type="gene ID" value="Caci_3011"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3011"/>
    <dbReference type="eggNOG" id="ENOG50325FJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_201927_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019396">
        <property type="entry name" value="TM_Fragile-X-F-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10269">
        <property type="entry name" value="Tmemb_185A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8515" checksum="69386D42A9F963C9" modified="2009-10-13" version="1">MSDSNSTTSGGLGFTGALTILFIALKLTHVLSWSWWWVLSPLWISAAAAIAVIGLVLLGAFIVETVKDRRKGVKMRGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Y3</accession>
    <name>C7Q4Y3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793660.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5071"/>
    <dbReference type="EnsemblBacteria" id="ACU73931">
        <property type="protein sequence ID" value="ACU73931"/>
        <property type="gene ID" value="Caci_5071"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5071"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_0_11"/>
    <dbReference type="OMA" id="GDDWIDY"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="410"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="496" mass="52176" checksum="849DF4184A0FC050" modified="2009-10-13" version="1">MTTLPHLLATRAAAEPERLALIVDGVGSLTIGDWETRSDAVAHAVLRRGLRLGDRVGLLFGSRNWIDYAICFLGVQKAGGVAVPLPPRAPAAELTRLLTDCAASGLLHEDASQPAPFDGWSASVSELEEAAAGDDQGPVDIEVRPGDLAQILYTSGTTGRPKGVAATHANLTHGCGGRRRPFAHSRHLAHAFPIGTNAGQVMLVNALDARLAVLSPARFTPARFARMIQEYAAGTVFLVPAMAVELLAGGSLEKYDLSSVVLLGSAAAPLPGAVAGKLVKAFPNATIANYYTSTEAAPAQTVMLYDPTRPGSVGRALAGGAVRIAASGSGAPVEAGQIAPVDEVGEVWLRSPTVSRTYYGDAESSREVFHSGWIRMGDLGYVDADGYLYLVDRDGDLVKSGAFKVSTLRVEEALYEHPDVLEAAVVGLPHPSLGKALAAVVVPREPVPAEQLREFLLERLAPHEVPSVIVEAEALPRNAGGKVDKRALLKESTWPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5I4</accession>
    <name>C7Q5I4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797519.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77795">
        <property type="protein sequence ID" value="ACU77795"/>
        <property type="gene ID" value="Caci_8982"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8982"/>
    <dbReference type="eggNOG" id="ENOG5033Z0C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_955434_0_0_11"/>
    <dbReference type="OrthoDB" id="2199658at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="31117" checksum="17001255B4147097" modified="2009-10-13" version="1">MIISSTPTYTFLGQCQRCIRPVRAEQPDTAGDRAQLTCPECQRTVPASRLYATRSTTACDGACMSAVGPNCSCSCEGANHGRSWSTLITEELTVGDALAAFRAKAAAEAARRAARLKRIADAFAARHRDVVEFLRDYDGDFQFLSDMQDKLREAGELSEAQAEGVRRCAERAAQRSAERAKREAARASAGPVPTGKVRVEGVVLTVKDYDAPGPSWSTTYKMLVALDNGSRVWSTVPKALAISYATTKGNWFGLRGARIAFTATVTAKNGDPSFGTASRPTGAELLVPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5K9</accession>
    <name>C7Q5K9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_9007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9007"/>
    <dbReference type="EnsemblBacteria" id="ACU77820">
        <property type="protein sequence ID" value="ACU77820"/>
        <property type="gene ID" value="Caci_9007"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9007"/>
    <dbReference type="HOGENOM" id="CLU_1080502_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="257" mass="28830" checksum="A027614A3C8DB025" modified="2009-10-13" version="1">MTSPPTPVDLHGYTARTVCWTLYKKDLRAEAVSARSRAGIGAAEVVPVRTFRQRGWALMIDRPDDHRAVLLGVDGRGIAVDLRPATRKPAPVREYQRDGQTWRMSPADFCLRHRSISTIDPSRRHEHGWWGPPHLGGDLVTQHWTELTLRATGPQPHQHDTMIVRCSRAARLTGWHAVAEDRLQVAEYHESSGLVTPAYRANSGFAPGFDRWLARAALWAIRDEDPAAVPVIDVPPTARDWDAYTDARIALETECAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Z5</accession>
    <name>C7Q5Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1166"/>
    <dbReference type="EnsemblBacteria" id="ACU70092">
        <property type="protein sequence ID" value="ACU70092"/>
        <property type="gene ID" value="Caci_1166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1166"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_287109_0_0_11"/>
    <dbReference type="OMA" id="PVDAWWV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="558"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1169" mass="120270" checksum="92CB983DFC175959" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q632</accession>
    <name>C7Q632_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="8" type="ordered locus">Caci_1204</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785423.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1204"/>
    <dbReference type="EnsemblBacteria" id="ACU70129">
        <property type="protein sequence ID" value="ACU70129"/>
        <property type="gene ID" value="Caci_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1204"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_4_3_11"/>
    <dbReference type="OMA" id="WYPDAKV"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="72" mass="7800" checksum="B466A9CF1BDC5805" modified="2009-10-13" version="1">MKPDIHPSYQVTTVTCGCGASFETHSTAPNGVIHAEVCSQCHPFYTGKQKILDTGGRVARFEARFGKKDASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B7</accession>
    <name>C7Q6B7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787416.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3216"/>
    <dbReference type="EnsemblBacteria" id="ACU72123">
        <property type="protein sequence ID" value="ACU72123"/>
        <property type="gene ID" value="Caci_3216"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3216"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045820_1_0_11"/>
    <dbReference type="OMA" id="IWIFPTT"/>
    <dbReference type="OrthoDB" id="1513550at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="43548" checksum="947731D26610427E" modified="2009-10-13" version="1">MNSHYDVIVAGGGSAGIAAAIGARRTGARTLLIERGPCLGGAATLRNVVTYCGLHTQQRRQVVFGVAEEMLAGLRALNAVSDPTSFKAVAVVFDPEAVKRVADELCEQAGVEVLLHSHICAATRDDDRITTVQVANHSGFQEYTAEAFVDASGEADLGHLAGAEVRYGNDGWVLNGTLGVRFGGIPSDAAMTREALSDAVRAAKASGASEELTSHTGLIARMPVSNDVITYLADESYDARSAVDTSRAERSARRQAQAYLRVLKSLPGCENAYIVSTGPEMGTRESRHLTGRMQLTEKDVLQPAPTAGCAAVGAWPIESHPGPGLPVEWQYIDDPGYYGIPLDVLWSRNTSNLFAAGRTVDGDRGAGASLRVMGTAFATGQAAGVAAAFTAAKSDVTPDAVRRELDRQGAHLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S0</accession>
    <name>C7Q6S0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793834.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5246"/>
    <dbReference type="EnsemblBacteria" id="ACU74105">
        <property type="protein sequence ID" value="ACU74105"/>
        <property type="gene ID" value="Caci_5246"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5246"/>
    <dbReference type="HOGENOM" id="CLU_146066_1_1_11"/>
    <dbReference type="OMA" id="FATWFLN"/>
    <dbReference type="OrthoDB" id="2037579at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="11205" checksum="F70A104F6EC51999" modified="2009-10-13" version="1">MSTETRTRFYHRRAPGDLIFLVAVIIAVIIIAHIIFVLLNANAGNDIVSTDGDWAAWFATWFLNLFTPDSHDLNITLNYGIAAVFYLVVGGIIRRLVNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6S9</accession>
    <name>C7Q6S9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol-phosphate phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7112"/>
    <dbReference type="EnsemblBacteria" id="ACU75942">
        <property type="protein sequence ID" value="ACU75942"/>
        <property type="gene ID" value="Caci_7112"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7112"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_6_0_11"/>
    <dbReference type="OMA" id="EDFLMEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="28719" checksum="CD58B1BDD39D8D83" modified="2009-10-13" version="1">MISFAELAEVEDIIRSVNEKTVLPRFRALRDSDVVMKGPNDPVTVADREAEDQLRERLTAFLPGSVVVGEEAVSEDASVLAALTGSAPVWIVDPIDGTRNFVAGSGRFSTLVALSVGGVLLASWTYAPVLGRIGTALAGHGAQVDGVPVRVAAAPADGTPTLPVTTSHPVWWPNGYGRGVDAMRAADLDVRYFDACGIEYLDLAAGSRSAMVITWEFCWDHAAGLLLVAEAGGHVAALDGAPVRLEGGNVLPFVASTDQATTDRIRTLIVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E1</accession>
    <name>C7Q7E1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1304"/>
    <dbReference type="EnsemblBacteria" id="ACU70229">
        <property type="protein sequence ID" value="ACU70229"/>
        <property type="gene ID" value="Caci_1304"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1304"/>
    <dbReference type="HOGENOM" id="CLU_1438691_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982990" evidence="1">
        <location>
            <begin position="29"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="20296" checksum="265F521A016BC6AB" modified="2009-10-13" version="1" precursor="true">MLRRRSLLALIAGVLLSFPSLAACPASASEEAGQSWVQASITAQLARKPGGVVDGDSIFYAKEDVTLTYKPATVPGSAVADDFAGCSTNEVCVYTTTDVISSGVRLSTGSLWCPWENTNNLLDLRDYGLADQIRAADSENGWWAEGIWSKLGVRGKQWKMDPHGILSNLSTTNITYLNVCIKEGDLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7F6</accession>
    <name>C7Q7F6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SMC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785538.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1320"/>
    <dbReference type="EnsemblBacteria" id="ACU70244">
        <property type="protein sequence ID" value="ACU70244"/>
        <property type="gene ID" value="Caci_1320"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1320"/>
    <dbReference type="eggNOG" id="COG4637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035814_3_1_11"/>
    <dbReference type="OMA" id="TCIAGEN"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041685">
        <property type="entry name" value="AAA_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13175">
        <property type="entry name" value="AAA_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_15" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="3">
        <location>
            <begin position="255"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="46320" checksum="651001E52E0B7EC9" modified="2009-10-13" version="1">MIITRIEIDGFKSFVDFSLDLHPFTVLIGANASGKSNVLDAVRFLTTAVSADLPSAVSSVRGDGESLFHQYSDGTRAPEMRFALEFLTDFGEHVGNRWRYEATIGRGGAAADRRMRYLSEVIERRLGADHWFDFVGASGQFRQLHQRDQGMRPDQAVAKRGLRRSLLGMTPVMSDGKEVAWLTDLALGLEGVKVYQFEGSALRQLSSMADEGQMASDGAGLPGYLHRIRESTRSEDHPVGAMADVQLELRGLLSDVPRFDVVVDNVRRDIRVEFAARNQPPFPASEASDGTLSALATIAALNDSEQTAPLLFDEPEAFLHPQAFRRLLRLLREMTSDPGNDEADWPLRQVVIASHSAEILREVPPAQVVVTSLVSRVDQGKVSTVTAVRRAGPSEARDSSAERAPMSREAVESFRSAGRSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7T8</accession>
    <name>C7Q7T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787574.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3375"/>
    <dbReference type="EnsemblBacteria" id="ACU72281">
        <property type="protein sequence ID" value="ACU72281"/>
        <property type="gene ID" value="Caci_3375"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3375"/>
    <dbReference type="HOGENOM" id="CLU_1101338_0_0_11"/>
    <dbReference type="OMA" id="RAPYHEP"/>
    <dbReference type="OrthoDB" id="1941959at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27219" checksum="534C4069E4A6CBEE" modified="2009-10-13" version="1">MISADDRKSDEELNEHEGEKPYAGLGEEPREDSVTEPDDVPGAEPVEGRFEVPVEDSRESAYADTKDLADAGEAGYAEETPYSEETPRTDEPSYTDEPAGIDEPGYTEEPAGIEESAYADEPAGIDEPSYTEDSVDTEEPAYAGAPVSAEASASSELDERNGEPLLAQASAEAFLGRWSDVQVAFIEDPHRSVAEADTLLSEILTAYQEAVEQRRSQISADSANNAADTEHLRLALLNYRTIITAMLPAHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q801</accession>
    <name>C7Q801_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5309</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793897.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5309"/>
    <dbReference type="EnsemblBacteria" id="ACU74168">
        <property type="protein sequence ID" value="ACU74168"/>
        <property type="gene ID" value="Caci_5309"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5309"/>
    <dbReference type="HOGENOM" id="CLU_093766_0_0_11"/>
    <dbReference type="OMA" id="RRTEDRI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="1" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981458" evidence="3">
        <location>
            <begin position="29"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="4">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="4">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="4">
        <location>
            <begin position="149"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="17757" checksum="73D1F6C913C89D78" modified="2009-10-13" version="1" precursor="true">MHGFVKKGLLLSLAAGSMMVAGAGAAAAADSAATDGAAADSPGLASGNVAQGAADVPVQVCGDAGAAGAALIDALENRCTTWDNRSSVRGVAANSPGAVSGDVVGGALNAPVQGCGLSGTVAGAQSDAAGNSCDDVRTAASAVGATSNDPGAVSGDVVQASVNTPIQVCGDAVSVGSFNTGAEDNHCVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z9</accession>
    <name>C7Q8Z9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787612.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72319">
        <property type="protein sequence ID" value="ACU72319"/>
        <property type="gene ID" value="Caci_3413"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3413"/>
    <dbReference type="HOGENOM" id="CLU_2367708_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980704" evidence="2">
        <location>
            <begin position="46"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="95" mass="9580" checksum="9668CD2ABF7BC0E6" modified="2009-10-13" version="1" precursor="true">MSPTSTTRHDKPKGARSGGARRALVAAVTVPITAAVLFGQGTAFAAENAENAGGATTATAANRPLDAADQQIAKNLDARVQDSRGTSWAASTASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q901</accession>
    <name>C7Q901_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_3415</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787614.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3415"/>
    <dbReference type="EnsemblBacteria" id="ACU72321">
        <property type="protein sequence ID" value="ACU72321"/>
        <property type="gene ID" value="Caci_3415"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3415"/>
    <dbReference type="eggNOG" id="COG0266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038423_2_0_11"/>
    <dbReference type="OMA" id="TYWCPRC"/>
    <dbReference type="OrthoDB" id="1162346at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08971">
        <property type="entry name" value="AcNei2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044090">
        <property type="entry name" value="Nei2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 17" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="16">
        <location>
            <begin position="2"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="15">
        <location>
            <begin position="222"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU72321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="28978" checksum="1CF744F04E4C6583" modified="2009-10-13" version="1">MPEGDSVFRTAAQLHEALAGDVLAVSDLRVPSLATSDLTGRRVLQTVARGKHLLTRLEGDLTLHTHLRMEGRWAVYRTGERWTGGPGWQIRAVLGTARNTAVGYRLQVVDLLPTSEEPTIVGHLGPDLLGPDWDAEEALRRLSADPARPLGLALLDQRNLAGVGNVYANELSFLARVPPWRPVGEVPGLEKVVDTAHRLLTLNRLRTGHVTTGETRADRRNWVYGRARQPCRRCGTRILTSSLGTPPKDRVIYFCPNCQPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9M8</accession>
    <name>C7Q9M8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="3">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_7370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795925.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7370"/>
    <dbReference type="EnsemblBacteria" id="ACU76197">
        <property type="protein sequence ID" value="ACU76197"/>
        <property type="gene ID" value="Caci_7370"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7370"/>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015667_2_3_11"/>
    <dbReference type="OMA" id="MGMTHGD"/>
    <dbReference type="OrthoDB" id="1588103at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="9">
        <location>
            <begin position="99"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="8">
        <location>
            <begin position="170"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="9">
        <location>
            <begin position="344"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="8">
        <location>
            <begin position="421"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="569" mass="63159" checksum="043BF056BEFD250C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X6</accession>
    <name>C7Q9X6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4352 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76295">
        <property type="protein sequence ID" value="ACU76295"/>
        <property type="gene ID" value="Caci_7470"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7470"/>
    <dbReference type="HOGENOM" id="CLU_1218034_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029051">
        <property type="entry name" value="DUF4352"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029050">
        <property type="entry name" value="Immunoprotect_excell_Ig-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11611">
        <property type="entry name" value="DUF4352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981494" description="DUF4352 domain-containing protein" evidence="3">
        <location>
            <begin position="37"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4352" evidence="4">
        <location>
            <begin position="97"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="22959" checksum="0AF17C67B41F5888" modified="2009-10-13" version="1" precursor="true">MSKRSTKSALLLGASAVLALAMTACSSSGSAPTAAGKTSATGSAAASTTASSAASSTSASDTSSAPSSGASDSDTASADPSATPPAITNKTSDWVERSGFKFKVDVVTYPYNPPAGYSLHPASNQEYLKLHVELANTAGAGAFSMMDLEVRDSADHEILPDIVATDELPANVRLNLLNLKPGEKQTGELVFIAPKGAKGLRLVFKGTLMTAQGTVTPGDPPVIDLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA18</accession>
    <name>C7QA18_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LPXTG-motif cell wall anchor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1493</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785710.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1493"/>
    <dbReference type="EnsemblBacteria" id="ACU70416">
        <property type="protein sequence ID" value="ACU70416"/>
        <property type="gene ID" value="Caci_1493"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1493"/>
    <dbReference type="eggNOG" id="ENOG5033GQX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_431951_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="1" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981498" evidence="4">
        <location>
            <begin position="30"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="224"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="283"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="339"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="409"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="5">
        <location>
            <begin position="464"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="550"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="633" mass="61833" checksum="E65131FA054006DC" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA36</accession>
    <name>C7QA36_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ordered locus">Caci_1513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA-binding protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785728.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1513"/>
    <dbReference type="EnsemblBacteria" id="ACU70434">
        <property type="protein sequence ID" value="ACU70434"/>
        <property type="gene ID" value="Caci_1513"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1513"/>
    <dbReference type="eggNOG" id="COG1837">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132074_3_0_11"/>
    <dbReference type="OMA" id="AVKMDKR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8836" checksum="E555152EC7C266D2" modified="2009-10-13" version="1">MLEEALEHLVKGIVEHPDEVRVRERDQRRGKVLEVRVHPDDLGKVIGRGGRTARALRTVMAALGGRSLRVDLVEAAGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG1</accession>
    <name>C7QAG1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3555"/>
    <dbReference type="EnsemblBacteria" id="ACU72460">
        <property type="protein sequence ID" value="ACU72460"/>
        <property type="gene ID" value="Caci_3555"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3555"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="LEWRPIF"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="36"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="583" mass="61574" checksum="871C437DA5712729" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAG9</accession>
    <name>C7QAG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792197.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3563"/>
    <dbReference type="EnsemblBacteria" id="ACU72468">
        <property type="protein sequence ID" value="ACU72468"/>
        <property type="gene ID" value="Caci_3563"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3563"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_0_1_11"/>
    <dbReference type="OMA" id="WHENLHA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="29128" checksum="8E170D1F1EB21A4E" modified="2009-10-13" version="1">MRFDILGPMEVCDGRTRLTPRAAKIRTLLAALLVSANTAVGTDTLITEIWGTNPPRTALHALRVYASEIRQMIAAMSDDPDRPALATWASGYCLELRSDMLDMLEFDRLCDEGQRAATNQCYELATENYRRALGLWRGPALLDVSCGVVLHSAARRLEERRIAAVKSRIDIDLRLRRHGQVVPELTELAARHPFNESLHVRLMVALHGSGRTGDALTVYRGLRDSLVAELGVEPNAQLQRVHLAMLTADQQVLDRQDLWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB54</accession>
    <name>C7QB54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796070.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76345">
        <property type="protein sequence ID" value="ACU76345"/>
        <property type="gene ID" value="Caci_7520"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7520"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_4_2_11"/>
    <dbReference type="OMA" id="HEVACGE"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="124" mass="13839" checksum="5A7014BA63E22A0F" modified="2009-10-13" version="1">MDTQVEQYELTHPSEDAVELTAVLSALAEPVRLTIVHTVADYAAEGGIACLDVWEKSGLTATKSTMSHHYKVLREAGLVVMWWVGAKKHVRLRRELMDVRWPGLLDAVLADTKAPQSVHAHEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH4</accession>
    <name>C7QBH4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1630"/>
    <dbReference type="EnsemblBacteria" id="ACU70551">
        <property type="protein sequence ID" value="ACU70551"/>
        <property type="gene ID" value="Caci_1630"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1630"/>
    <dbReference type="eggNOG" id="COG0452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118224_0_0_11"/>
    <dbReference type="OMA" id="PCVNAAY"/>
    <dbReference type="OrthoDB" id="1429052at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18140" checksum="0C34B218CE063737" modified="2009-10-13" version="1">MPVLYLIACGAPPAAELLSHPEAVPGLQADGWTVCVLCSPNGERFLDTAAVSIATGYPVRVEQRLPGEPDVLPSPDAILVAPATFNTLNKWALGISDTLVLGILNENLGAGLPIAATIWAKDELQKHPAFDAHAQLLFESGVRFIQPDEDVQQFPWRQLRLAMAELLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBU0</accession>
    <name>C7QBU0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UbiD-like decarboxylase</fullName>
            <ecNumber evidence="1">4.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ferulic acid decarboxylase-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible decarboxylation of aromatic carboxylic acids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="1">
            <name>prenyl-FMN</name>
            <dbReference type="ChEBI" id="CHEBI:87746"/>
        </cofactor>
        <text evidence="1">Binds 1 prenylated FMN (prenyl-FMN) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiD family. UbiD-like/FDC subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792288.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3657"/>
    <dbReference type="EnsemblBacteria" id="ACU72559">
        <property type="protein sequence ID" value="ACU72559"/>
        <property type="gene ID" value="Caci_3657"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3657"/>
    <dbReference type="eggNOG" id="COG0043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023348_0_0_11"/>
    <dbReference type="OrthoDB" id="1012819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01983">
        <property type="entry name" value="UbiD_FDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032903">
        <property type="entry name" value="UbiD/Fdc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="prenyl-FMN binding" evidence="1">
        <location>
            <begin position="166"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="prenyl-FMN binding" evidence="1">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="497" mass="54204" checksum="49C0DDF91B886C38" modified="2009-10-13" version="1">MTHLRSLREFIEALDEIGEIQRIDREVDWNLEAGAITRRSYDLRAPAPLFTNLTGYQGTGFALLGAPGALSGPEHRLARMALAVGLPATATGQQIVEVLADARAKPGIPPVVVDKAGAPCKENILTGEDIDLFAFPTPLIHGNDGGRYIQTYGMNIAKTPDGSWTNWSINRMMIADRNTLACLIPAPQHLGIIRAQWTQIGEPMPIALAVGVEPGLPWVGGMPIPEGMDETHYLGALFGEGIELVPAESVDLLVPATAEIVVEGYISLDETVMEGPFNEFPGYIATDATPKQVFHVTAITHRDGAIQPIVAAGPPVEENHTIIGTTSAAEILYLLREADLPISSAWYNYEAAVHWLTLAVRQDWHTATGLSSTDLVQKIADIIFTGKPSVNAPKILLVEDDVDITDLEQVVWAFATRSHPDVNRGEFHFPPKVSDQLAVYLSPEEAHTFMAGKVIYNCLLADLFPEGARPIKGSFENGWPAEIQQRVLENWQAYGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBX9</accession>
    <name>C7QBX9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3696"/>
    <dbReference type="EnsemblBacteria" id="ACU72598">
        <property type="protein sequence ID" value="ACU72598"/>
        <property type="gene ID" value="Caci_3696"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3696"/>
    <dbReference type="eggNOG" id="COG1944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020793_1_0_11"/>
    <dbReference type="OMA" id="INDRTYQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022291">
        <property type="entry name" value="Bacteriocin_synth_cyclodeHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027624">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03882">
        <property type="entry name" value="cyclo_dehyd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03604">
        <property type="entry name" value="TOMM_cyclo_SagD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="255"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="644" mass="69740" checksum="61781CD8F3B4A491" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBY7</accession>
    <name>C7QBY7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792335.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3704"/>
    <dbReference type="EnsemblBacteria" id="ACU72606">
        <property type="protein sequence ID" value="ACU72606"/>
        <property type="gene ID" value="Caci_3704"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3704"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="ASHEHFA"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="37334" checksum="B74DD14D58AF0968" modified="2009-10-13" version="1">MTPTPARRLSEVAQKVGVSEATVSRVLNNKPGVAEGTREAVLTALDVLGYERPTQLRGERARLIGLVLPELQNPIFPALAEVVGGALAQRGFTPVLCTRTAGGLSESAYVDMLLDQHVSGVVFCGGHYAEADAPHDHYRLLKDRGVPVVLFNAAVEDLGFPAVSTDDEVACEQSYGHLESLGHERVGLVVGPEDHMPSRRRVAAFLAEAERAAKRAPGYGARRLSVVVEHAQFSMEGGRAATARALAQGVTAVVCGSDVLALGAIRAVRRSGLDVPRDVSVVGFDDSSFMNCTDPALTTVRQPIEAMGRAAVAMLLKQVEGGRMNTEELLFEPELVVRGSTGPVRDPGAGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCF0</accession>
    <name>C7QCF0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74598">
        <property type="protein sequence ID" value="ACU74598"/>
        <property type="gene ID" value="Caci_5740"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5740"/>
    <dbReference type="HOGENOM" id="CLU_1092779_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983020" evidence="2">
        <location>
            <begin position="40"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="25278" checksum="BEC00AD2ECB37631" modified="2009-10-13" version="1" precursor="true">MTEFLVGRRPMRNIAGICVAAITAAALQGCASSGTVATAKTGTATPTTVPTSTATITGTAPSPDATDTATATGTPAATGTPAATGTSAASSPPPNTAPAAAGGWTPQGQLANSEPVDQVVNADKSVTATWPKGAPAGHALTVKLRAARNGTKIVIHLAIDNESGRQVSMNEGVFTGGAVLDAQGNDLNMENFDPLWTLGSGSSDGNVDPGQPLTGDFVVDAPASGSTLNAYWTQAVSENGIMAGIILIRDIPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD76</accession>
    <name>C7QD76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_3767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792398.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3767"/>
    <dbReference type="EnsemblBacteria" id="ACU72669">
        <property type="protein sequence ID" value="ACU72669"/>
        <property type="gene ID" value="Caci_3767"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3767"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_2_11"/>
    <dbReference type="OMA" id="FYQWDRF"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU72669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="352" mass="38361" checksum="F6554D3994F00B80" modified="2009-10-13" version="1">MTSVNAPDAVPVGEGSGAPPPQPRQPPDPVGHARSAEESAPTSAFTAQRVIPLRHPGRWIATVAVLVLAAQFAHGLITNPFYQWDRFEYWFARPVIMRGLVVTLRVTALSAVLGLAGGVLLALARQSRNPVLNLVSWLYIWVFRSVPLIVVLLILFNFSALYKTLSLGVPFGPGFFHFDENRLATELVVATVGLSLNEAAYAAEVVRAGLLSVDQGQHEAAASLGLPRGYQFRRIVLPQALRAIVPAYVNQLIGLIKGTSLVFYVSLLDLFGQVQTMGSTYPADIVPLLLVATAWYVILTSVVSAVQFYVERRYSRGALRTLPPTPIQRLRAGARNAVRQLRDRPELGPVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDC3</accession>
    <name>C7QDC3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792445.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3815"/>
    <dbReference type="EnsemblBacteria" id="ACU72716">
        <property type="protein sequence ID" value="ACU72716"/>
        <property type="gene ID" value="Caci_3815"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3815"/>
    <dbReference type="eggNOG" id="COG4709">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_843821_0_0_11"/>
    <dbReference type="OrthoDB" id="2089615at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="33946" checksum="52FBB423364BA280" modified="2009-10-13" version="1">MSTGADELVAEYLRELEREAARLPWNARTELLEDVRSHIEVVRAEAGDVGGSGVSDDASGVAGASGSPDPSGSSATSGDEEARVIKVREILAALGEPREIVDAAAADEADSPMPRLVTQPMPPIVPTDPMSAYADPLGGPPYPLGTAEIGAVALLLGGFLLAGFGWLLGVILLWTSPRWNVREKLVGTFVLPGGLGFLLLALMTPTSTQSCVSGPGYKHCTSSGWTLPQWASFVMVTLCLLLPIWTSAFLVRSARRRSGTSRPGRDRSGTVFAIGGGALAVILIGGFAFAVFSGSSSSSGVTPSSPAVSYSASSVQEPTAPVSSSSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDD5</accession>
    <name>C7QDD5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3829"/>
    <dbReference type="EnsemblBacteria" id="ACU72728">
        <property type="protein sequence ID" value="ACU72728"/>
        <property type="gene ID" value="Caci_3829"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3829"/>
    <dbReference type="eggNOG" id="COG2319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_420169_0_0_11"/>
    <dbReference type="OMA" id="WNIATRA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="389"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="480"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="526"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="572"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="618"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="652" mass="69531" checksum="F902095D36551A9A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDJ5</accession>
    <name>C7QDJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
            <ecNumber evidence="5">5.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5761</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5761"/>
    <dbReference type="EnsemblBacteria" id="ACU74619">
        <property type="protein sequence ID" value="ACU74619"/>
        <property type="gene ID" value="Caci_5761"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5761"/>
    <dbReference type="eggNOG" id="COG1609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_4_11"/>
    <dbReference type="OMA" id="SHYQAMI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="363" mass="38768" checksum="15BC1CB205694D7A" modified="2009-10-13" version="1">MSTADSDGAVLMPRIDQTGAAVGDSSLTDVAVRAGVSTATVSRALRGLPSVTEETRARIKAVADELGYVVSPSASRLATGRTHTVGVIVPSIDRWFSGQVIKGVEQVLRAAGYDLLFYNLGDDEGRARFFEAMPLRRRVDAVLVLSVPLQDPEVAKLRSLHLPIGLVGASADTFSSVRIDDLAGAATAVRHLIGLGHRDIALISGGTDVPPHFTTPTDRRRGYLDALAASGIGYDPALEAAGDFTITGGERAMSHLLGRPHHPTAVFALCDEMAFGAMRVLRTSGLRIPRDISVIGFDDHEMSDLLDLTTIRQPVVEQGATIARLLLDRLSAEAHTRPHQNEVSLPTQLVVRGSTAPRRARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDX6</accession>
    <name>C7QDX6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="3" type="ordered locus">Caci_7740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796289.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7740"/>
    <dbReference type="EnsemblBacteria" id="ACU76564">
        <property type="protein sequence ID" value="ACU76564"/>
        <property type="gene ID" value="Caci_7740"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7740"/>
    <dbReference type="eggNOG" id="COG0858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089475_0_0_11"/>
    <dbReference type="OMA" id="GDLQHCK"/>
    <dbReference type="OrthoDB" id="1971380at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16274" checksum="C944F391F9C28F9B" modified="2009-10-13" version="1">MANNGTRAAKLADRIRVIVAETLKMRVKDPRLGFVTITDVRITGDLRDATVFYTVLGGEEERAETAAALESAKGVLRTEVGRQTGVKHTPSLTFIADAIPEGARNIEDLLAKAAVSDAAVRDAAATAAYAGEPDPYRAPRADDEFDDEDEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE36</accession>
    <name>C7QE36_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796349.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7800"/>
    <dbReference type="EnsemblBacteria" id="ACU76624">
        <property type="protein sequence ID" value="ACU76624"/>
        <property type="gene ID" value="Caci_7800"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7800"/>
    <dbReference type="eggNOG" id="COG0695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026126_11_1_11"/>
    <dbReference type="OMA" id="EGIAYTE"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011915">
        <property type="entry name" value="GlrX_actino"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02200">
        <property type="entry name" value="GlrX_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="84" mass="9007" checksum="2AE762DD71DF2B75" modified="2009-10-13" version="1">MDDQITMYSTSWCGYCRRLKSQLEREGIGFAEVNIEQVPEAADYVMSVNGGNQTVPTVVVVAPGGEKVAMTNPSLAQVKQAAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE47</accession>
    <name>C7QE47_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796360.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7811"/>
    <dbReference type="EnsemblBacteria" id="ACU76635">
        <property type="protein sequence ID" value="ACU76635"/>
        <property type="gene ID" value="Caci_7811"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7811"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_4_11"/>
    <dbReference type="OMA" id="IDVTAYR"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisKA_3" evidence="1">
        <location>
            <begin position="59"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="30695" checksum="AE8D28DF8D2515B8" modified="2009-10-13" version="1" precursor="true">MLWVLVGALLVAGAAGAAASRLAVLLRRERGRYTRAIEERGWLLERERESAAQQAVDLERSRIARELHDIVSHNVSMMLIQAGAARQVLAAAPAQSATAEEPAASGVAEDALLAVESAGRATMTELRHLLGVLAPAADGRDQPGAGADPALAPQPTLSRLSALVDKIAFAGLPVDARISGEPRPLPGGIDSTAYRIVQEALTNALKHGGRDAALTIRYDDRYLRIEILTAGHGSLDEVGTEPAPRGGERIGTGRGLTGLKERVAVYGGDLDARRRLGGGFRVRAKIPLDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE61</accession>
    <name>C7QE61_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796374.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7825"/>
    <dbReference type="EnsemblBacteria" id="ACU76649">
        <property type="protein sequence ID" value="ACU76649"/>
        <property type="gene ID" value="Caci_7825"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7825"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_12_4_11"/>
    <dbReference type="OMA" id="KPMRVPR"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="32867" checksum="4CC4B6D5DB09F92A" modified="2009-10-13" version="1">MRILLAGASGVFGRVLTPALIDAGHEVVGITRTPDGVRAIEAMGAGTVVADVMDRAELLAAVEGHHFDAVISQLTALKKPPMRNKDMDVTNTLRTVGTENLMAAAKATGATRFLTQSMIFGYGYGDLGPGRITEDAFFGPSPRRAFARHGEAMLRNEQIAFSEPGIDGIALRYGLFYGGPATNAYVEGLQAGKMPLVKAGTNSFVHLADAASATVAAVERGKGGEAYNVVDDAPAPFADVALEIAKDFGTKTPRTVPAWLTKPMPYLHCFITGRWIVSNAKAKDQLGWQPQYPSFHEGVHADARAAGIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFJ8</accession>
    <name>C7QFJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796500.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7952"/>
    <dbReference type="EnsemblBacteria" id="ACU76775">
        <property type="protein sequence ID" value="ACU76775"/>
        <property type="gene ID" value="Caci_7952"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7952"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_9_3_11"/>
    <dbReference type="OMA" id="FDWGGVF"/>
    <dbReference type="OrthoDB" id="1669868at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="22527" checksum="F22DDFAC79F69741" modified="2009-10-13" version="1">MTWIVFDYGEVIAHRPPASDFARLAEMAGAPAEEFAEGYWLFRDKFDRGMPALDYWQAVGAEARVTVGPDEAEALSAADVELWNTLDPQSVELVADLAAAGRRLALLSNAPIAHGAAFRTREWAAPFEHFVISGELGVAKPDAAIWQALLDQLRAPAREVFFLDDREVNVAAAREAGIRAFLWTGAGDARRHIAEFDAEFPPAAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFN2</accession>
    <name>C7QFN2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU68971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0016"/>
    <dbReference type="MEROPS" id="S01.494"/>
    <dbReference type="EnsemblBacteria" id="ACU68971">
        <property type="protein sequence ID" value="ACU68971"/>
        <property type="gene ID" value="Caci_0016"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0016"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_3_5_11"/>
    <dbReference type="OMA" id="QFNGDTG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU68971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="39558" checksum="27ED4E6F234AAE22" modified="2009-10-13" version="1">MTGFEHDPYQPEQPATGDPQPWGHPSSGPVLGPAHASASAYPPAYPSASSPSPAASEPMPPYTPPITSITPGYGNPGEAGGLGGPGSFGGPGGFGGPGGPGGPGYTTHPAFSPEPPRRPRRKRRMGMALIIAGTIAASAAAGGIAGTIASHNNSSNSASSSVPLNNTSVNTPVSNQTGTPTTTVGQVAKAALPTVVQVSVESYQGKSVGSGVILTADGLILTNNHVITDAANGNGQITITFNNGKTAQASIVGYDSGSDLAVIKAQSVSGLPTASLGDSSKIQIGDTVVAIGSPDGLQSTVTSGIVSALNRQVTVSSESSSRFSSGSQVTYSAIQTDASLNPGNSGGPLLNAQGQVIGINSAIYSPTSSANAQGGSVGLGFSIPIDQVKTMLAKLEGGQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG02</accession>
    <name>C7QG02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Copper resistance D domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2060"/>
    <dbReference type="EnsemblBacteria" id="ACU70979">
        <property type="protein sequence ID" value="ACU70979"/>
        <property type="gene ID" value="Caci_2060"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2060"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_670401_0_0_11"/>
    <dbReference type="OMA" id="FLYWEHV"/>
    <dbReference type="OrthoDB" id="1540490at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="7">
        <location>
            <begin position="218"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="400" mass="41787" checksum="3F48B0F6301409B4" modified="2009-10-13" version="1">MLSAPVLAGAPAYLAAPAPSTPLGPFEDSAVSWASWATLMSFVGLVALALVVAAPARGAGERTARIVRTRLGWAAVVAGVLALPAVLTDQAHSASRTGYDYGAAWRGLFDGSGAGLLAGLETVLPFVAALLILPVVIRRALPARLVTGLRVAALILGVVGLVSTRIPTSLADNAGRTVFQTFMWILHLIGGGVWVGGLIGLVVLVAGSGLESGFWSPAIRRFSIAAMSCVAAISLSGLFLYWEHVDGPTQLLSTMYGRVLGVKLLIFGSLLALGAVNQFWLHPRIDALRAAGDERPLRTVLVRRFPAVVGVETVLILGLLFAASFLHGSARNQAFQADAAKHATGSVKKLPKLPQKEVSASTWIEGTAETAAVLVVTVAGYRFSGKLARRRVGRVRPAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL9</accession>
    <name>C7QGL9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Bacterioferritin</fullName>
            <ecNumber evidence="5">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6042</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6042"/>
    <dbReference type="EnsemblBacteria" id="ACU74899">
        <property type="protein sequence ID" value="ACU74899"/>
        <property type="gene ID" value="Caci_6042"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6042"/>
    <dbReference type="eggNOG" id="COG2193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104506_2_0_11"/>
    <dbReference type="OMA" id="YQRLFHV"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00754">
        <property type="entry name" value="bfr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00549">
        <property type="entry name" value="BACTERIOFERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0409">Iron storage</keyword>
    <keyword evidence="5 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="8">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU74899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="18538" checksum="2D5BA69A90DECDB9" modified="2009-10-13" version="1">MQGDKDIIAFLNEQLTAELTAINQYWLHYKLQDNRGWKKLAEYTRAESIDEMKHADKLAERIIFLEGLPNFQKLFPLEIGQSVTEMFQADMKVEVAAVERLRNGIKLMRERGDVTSANLFEEILADEEHHIDYLETQLDLISQLGEPLYIAQLVEQPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM1</accession>
    <name>C7QGM1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6044"/>
    <dbReference type="EnsemblBacteria" id="ACU74901">
        <property type="protein sequence ID" value="ACU74901"/>
        <property type="gene ID" value="Caci_6044"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6044"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="NVLRKTQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="159"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="226" mass="24331" checksum="E350F304AC84EF74" modified="2009-10-13" version="1">MSDPITVVLVDDHQMFRAGVRTELHRAAKAAGAQAGAPIEIEIVGEADETARAVEVIAATRPQVVLLDVHLPGGGGVEVLRQTAPALPDVRFLALSVSDAAEDVIAVIRAGARGYVTKSISGAELADAVRRVADGDAFFSPRLAGFVLDAFASGGAAARDEELDRLTPREREVLRFIARGYAYKEVARELVISIKTVETHVSSVLRKLQLSNRRELTRWASDRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGU2</accession>
    <name>C7QGU2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6117"/>
    <dbReference type="EnsemblBacteria" id="ACU74972">
        <property type="protein sequence ID" value="ACU74972"/>
        <property type="gene ID" value="Caci_6117"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6117"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_16_11"/>
    <dbReference type="OMA" id="RAWRMLY"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="197"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="31859" checksum="B616A7D1286EA759" modified="2009-10-13" version="1">MAGTRGWAEYWRDDSRGLEAMHARFRDHVYAPHSHDAYSFGVTDAGAQQFHCRGGLHTSAAGMVMVLNPDDPHDGRAAADLGYHYRIVHVSPQIVRAVLADAADLTDHADPLEVAASSASAFAGSAVPLPLFTRPVLGDRRLADAIAGLHAALAADASPLARDERLRAVILGAHLRGATRPPRIRTLNDGAQREAAHRARTLMREAYPEPLPVEVIAEAAGCSRFALYRAFSAEFGMSPSDYERQLRLRHARSLLAAGSAPADVAAATGFADQAHLARWFKRAYGITPGVFARGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH51</accession>
    <name>C7QH51_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8078"/>
    <dbReference type="EnsemblBacteria" id="ACU76901">
        <property type="protein sequence ID" value="ACU76901"/>
        <property type="gene ID" value="Caci_8078"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8078"/>
    <dbReference type="eggNOG" id="ENOG5031RMA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094182_0_0_11"/>
    <dbReference type="OMA" id="GTETHDR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025324">
        <property type="entry name" value="DUF4230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14014">
        <property type="entry name" value="DUF4230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="24963" checksum="D14D603AA7ADD543" modified="2009-10-13" version="1">MAAKDEPVQEGSKNETRIIVDTKRGGWRSSLLRWGGGAVVVVVILGFLGSLTNLIHFGNPFGETTTVRSGPVLLKSITELKRFEAASGEFQVVTEVQNSSWLPSFLAGSDTFFLGDGTVGVFVDFSNLDANHVKVSPDRLSATITLPKPVLDPTALDVHKSYIIGQQEGLFDRLFSSDPNKVQPLLVEATKQIDGAAAKSNLVSIGEKDTTQMLQGLLHSLGFTGTITVTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHS9</accession>
    <name>C7QHS9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2185"/>
    <dbReference type="EnsemblBacteria" id="ACU71104">
        <property type="protein sequence ID" value="ACU71104"/>
        <property type="gene ID" value="Caci_2185"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2185"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_825901_0_0_11"/>
    <dbReference type="OMA" id="WVGEMAT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022526">
        <property type="entry name" value="F420_Rv3093c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03841">
        <property type="entry name" value="F420_Rv3093c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="102"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="357" mass="37345" checksum="28C3773C9E4C1847" modified="2009-10-13" version="1">MSQVIVDGVLLGNRTDSDPALTVRLACLADELGYQEIWLGESTGHDAFALAVAVAAAAGELPSAGPGPDGKARPPGANPATAGEFRRTNPTRPLAALTLGPLPAAVRDPVTAARGAASVAALTGRDIGLALTASTGLVVVDWHGRPRTDPATALAESLSVLAPLTRGEPVSFQGVSVRSRGFRSRLEPSHASLTVLAFGLEACEVAVGRADRVAVPLATVEHAARIKARLALTSDRMNRAVPRLAVFLPTVVDPDAESLDWIRRSLLPYLDADGFGRMFAEAGHGELIDLARGGAHERSLLAAMPEEVLRSIAAVGDLNQVCTAFEDYRQAGVDEIVMLPESYDAGVIEHTIRALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHV9</accession>
    <name>C7QHV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_2215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786427.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2215"/>
    <dbReference type="EnsemblBacteria" id="ACU71134">
        <property type="protein sequence ID" value="ACU71134"/>
        <property type="gene ID" value="Caci_2215"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2215"/>
    <dbReference type="eggNOG" id="COG0488">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_0_11"/>
    <dbReference type="OMA" id="DKMFLDN"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="344"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="382"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="545" mass="58737" checksum="16B7965AB576B47B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI85</accession>
    <name>C7QI85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-Ig-H3/fasciclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792859.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4266"/>
    <dbReference type="EnsemblBacteria" id="ACU73130">
        <property type="protein sequence ID" value="ACU73130"/>
        <property type="gene ID" value="Caci_4266"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4266"/>
    <dbReference type="eggNOG" id="COG2335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031281_3_1_11"/>
    <dbReference type="OMA" id="ICGGVQT"/>
    <dbReference type="OrthoDB" id="1776069at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982905" evidence="2">
        <location>
            <begin position="36"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="92"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="225" mass="21733" checksum="DD780031C7EDA8DC" modified="2009-10-13" version="1" precursor="true">MFSTRSKTAAALLCSAAIAVSASACSSSASKTAAASSTSSSSMASSTTPAAGSTSATTSSDTSTAAGSTAAFGSACSAVPTTGPGSFTGMATDPVATAASHNPVLSTLVTAVGAAGLGDTLNSAQNITVFAPANDAFTKIPAATLKSVLADKAQLTKILTYHVVSGKLTPTQLAGTHTTLEGGTLTVTGSGQSFQVNGANVICGNVQTANATVYIIDTVLTPPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI96</accession>
    <name>C7QI96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4277</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792870.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4277"/>
    <dbReference type="EnsemblBacteria" id="ACU73141">
        <property type="protein sequence ID" value="ACU73141"/>
        <property type="gene ID" value="Caci_4277"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4277"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="FTRHVGR"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="211"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="34090" checksum="6C9C19BE96780649" modified="2009-10-13" version="1">MTAPPENLADRPAATDSDLPHDLLSELLRSVRLTGERIVAYTPSPLFSVEFADRGSLHIVEEGEVTLRIEGSPHVEHLCAGDFVLLPRGDAHSISDAGLGGSPAGGDADRRPARWLCGTFTIGDPQASHLLGSLPAVIILRGSGGPDLEALEGLEVARRMIVLEMQSPSQGSAVMVARILDLIFIQIMRTWAAGADVEPNWLAGAFDPQIGLALSAIHRDPGREWTVEELARACNLSRSSFAARFVERVGKPPATYLAHVRLDAATTLLRDTFLPVTQVAETVGYASEAAFSRAFKNRYGTPPARWRRDIRYPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIK0</accession>
    <name>C7QIK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794806.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6223"/>
    <dbReference type="EnsemblBacteria" id="ACU75077">
        <property type="protein sequence ID" value="ACU75077"/>
        <property type="gene ID" value="Caci_6223"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6223"/>
    <dbReference type="eggNOG" id="COG3178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_715138_0_0_11"/>
    <dbReference type="OrthoDB" id="1236219at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="41002" checksum="586FC95D30CF3AEF" modified="2009-10-13" version="1">MPDSATPLHLGAVEAALTEVCGAPVAVERWDPIEPWAVARVLVSGVEGSRTVIVKWLRAGTALARAERWRLATELAALRFLRDDLALAIAPRVIAADLPGGFLVLDDLAPRAALDQLICRDGAGAHRERLAAFARALGELGAATAGHGERYRARCDALGVPRSAADQRSRFTTLWTQGHQDATALGVPIAGAAASELTAAFDELCSPGPFLALSNGDAESNNCLVHESGPADARLIDFEAGGYVHVLLDAVCLYVPGPRWISVGDPTGSGGLAEHYRRALAEGVPQAQDDQRYGFGLAAACTAWALLRLQRLADIDARVPGDHSRLQLVETVESAARTADAYRALPALSGWLRSAGEALRRRWPDADVDVSDPVAFPPYTPRVRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIK1</accession>
    <name>C7QIK1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794807.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6224"/>
    <dbReference type="EnsemblBacteria" id="ACU75078">
        <property type="protein sequence ID" value="ACU75078"/>
        <property type="gene ID" value="Caci_6224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6224"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_10_3_11"/>
    <dbReference type="OMA" id="CAFVGAR"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="201"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="383" mass="37623" checksum="3C30DCD357630E90" modified="2009-10-13" version="1">MPVLRGPRCRGLRGGLRAGRDSGAGGCATLQELPPFLSAKFHVGPAVTGLVVGAAFAATAAGRPFAGRWGDAGRSRAVVVLGGLLASAAGAGTVFAPDVAVLLLCRLVMGAGEAALFSGALPWVLADVLPEQRGRVAGWFGLSMWGGLTLGPVLAATIGEAANADAVWWTVAALPLVSAVLAATARKPEFVTTKRIPGPLVPPGVSLPGSIIGLAAYGYGTLAAVLVLSLGHSAGKVVALPVFACAFLVVRGFGSPLVDRHGGAVVACVTLVVQAAGLILLAAAPDLVVTLAGAAITGAGLGLIYPATAAMTLGMARAETAGAAVGAMTSFWDLGILVAGPLSGTIAAAAGFHAAFGVAVVTTVLAVILAVRTSMSGVAASVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIL8</accession>
    <name>C7QIL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794824.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6241"/>
    <dbReference type="EnsemblBacteria" id="ACU75095">
        <property type="protein sequence ID" value="ACU75095"/>
        <property type="gene ID" value="Caci_6241"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6241"/>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100275_2_0_11"/>
    <dbReference type="OMA" id="PVEYYLA"/>
    <dbReference type="OrthoDB" id="1430018at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="182" mass="19457" checksum="23F71583E35038C2" modified="2009-10-13" version="1">MTTVTNGVNVQALLDAREVLKGAPEAAQFTWRATSTWRDGVHSTTTVKDFFGLGEEHNHKTESVFEADHPAVFAAEDNGITPIEYLLVGLAGCLTAGVASVAQNRGIQLRSVSSTVEGRHDIRGILGADSDVRNGFTDIKVSFSIDADASQQEIEALVAQSQKRSAVFDALTNPTDVTVEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM3</accession>
    <name>C7QIM3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8100"/>
    <dbReference type="EnsemblBacteria" id="ACU76923">
        <property type="protein sequence ID" value="ACU76923"/>
        <property type="gene ID" value="Caci_8100"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8100"/>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079909_0_0_11"/>
    <dbReference type="OMA" id="LFVIMDP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21558" checksum="FA05034A05EEAFC0" modified="2009-10-13" version="1">MFDSKLFLEAYITLFVIMDPPGTLPIFLALTNGRSKAQRTRAAWQAALVAFCVICVFALFGQQILDYLGVTLPALQGSGGLLLLLIALELLTGRSEEPSHSNEAVNVALVPLGTPLLAGPGAIVAVMVFAKRTDHHWSGVLAVGAAIVAIHITLWLTMRFSVQVIRVIKDSGVTLVTRIAGLLLSAIAVQMVADAVRAFIKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS0</accession>
    <name>C7QIS0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="7">MECDP-synthase</shortName>
            <shortName evidence="7">MECPP-synthase</shortName>
            <shortName evidence="7">MECPS</shortName>
            <ecNumber evidence="3 7 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispF</name>
        <name evidence="10" type="ordered locus">Caci_8147</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796695.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8147"/>
    <dbReference type="EnsemblBacteria" id="ACU76970">
        <property type="protein sequence ID" value="ACU76970"/>
        <property type="gene ID" value="Caci_8147"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8147"/>
    <dbReference type="eggNOG" id="COG0245">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084630_1_0_11"/>
    <dbReference type="OMA" id="QHFGTGR"/>
    <dbReference type="OrthoDB" id="1716560at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="9">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="39"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU76970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="16118" checksum="E68350063EB5F3F4" modified="2009-10-13" version="1">MTALLPLVGIGVDVHAFADGRELWIGGLHWPGEVGLAGHSDADVVAHAACNALFSAAGLGDLGAQFGTSDPEWAGASGLKLLGEAARRVREAGFEIGNVSVQLVGVRPRVGGRRAEAEQVLSEAAGAPVRLAAATTDGLGFTGRGEGLAGIATAIVFPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS5</accession>
    <name>C7QIS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase, TrmH family, group 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796700.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8152"/>
    <dbReference type="EnsemblBacteria" id="ACU76975">
        <property type="protein sequence ID" value="ACU76975"/>
        <property type="gene ID" value="Caci_8152"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8152"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_0_0_11"/>
    <dbReference type="OMA" id="QVPPYEY"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="2">
        <location>
            <begin position="94"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="339" mass="35085" checksum="82442675E1F5F767" modified="2009-10-13" version="1">MATKGGGAGGRANKPGASSSRKGAQKGSGGQRRQGLEGRGPTPKAEERTGHPAARRAKSAAKRSAAASNPRSGAGTRGTSRPARRTPGKGEAEQVAGRNSVVEALRAHVPAKALYIAQYIDSDDRVRESMRLATELGVPLLEAPRHELDRMTNGTLHQGVMLVMPPYEYAHPDDLLEEVFAAGDTPLFAALDGVTDPRNLGAVMRSVAAFGGHGVIVPERRAAGMTAGAWKAAAGAGARLPVARAGNLTRALEAYKKQGVMVAGLAADGSVPLHELEIATEPLCLVIGSEGKGMSRLVSELCDVTVSIPIASTTESLNAGVAAGIALYEVNRRRAEARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ20</accession>
    <name>C7QJ20_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0207</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0207"/>
    <dbReference type="EnsemblBacteria" id="ACU69162">
        <property type="protein sequence ID" value="ACU69162"/>
        <property type="gene ID" value="Caci_0207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0207"/>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="PARMLTT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="288"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="354"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="566" mass="59383" checksum="4F5B5E425CD00942" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ54</accession>
    <name>C7QJ54_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784491.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0243"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69196">
        <property type="protein sequence ID" value="ACU69196"/>
        <property type="gene ID" value="Caci_0243"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0243"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_6_0_11"/>
    <dbReference type="OMA" id="GQRCLTR"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="233" mass="24782" checksum="EAB56A1687F7FA17" modified="2009-10-13" version="1">MEAEPVTEVTSSDVFVIIPAWNEQERIAATVRAAAALGPVLVMDDGSRDATTRIARRAGARVLTTRNNLGKGAAMAAGVAALPQQARYVLFLDADLEDTASQAGPLVDAVRSGSCDMAIALPPPQPGGGHGLVVGLAREGIKRLTGFDAAAPLSGQRCLTREAAEAVRYAARFGVEVGLTIDLLRAGYEVAEVPADLRHRVTGEDWRSQIHRARQYRDVLLALRSRSLPPRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJI1</accession>
    <name>C7QJI1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2286</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786497.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2286"/>
    <dbReference type="EnsemblBacteria" id="ACU71204">
        <property type="protein sequence ID" value="ACU71204"/>
        <property type="gene ID" value="Caci_2286"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2286"/>
    <dbReference type="eggNOG" id="COG4689">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049360_0_0_11"/>
    <dbReference type="OMA" id="YVHQRYD"/>
    <dbReference type="OrthoDB" id="978501at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="30516" checksum="8BD528E2F88D14EF" modified="2009-10-13" version="1" precursor="true">MPRVRYGPRDLEAVAAARESAAKLPDLWSTGVHAVWETDPDALAQVLPPPLKPTAKPYVRATINQVDMSVFDDHQHSGAPLGAAAISVACAHGGEEGWYSLVMPMTTERSLIGGREVFGEPKKLAEVVVDRDGEQVAGTVTRHGVTFAEIRGRIAGALEPPAPYVKVDWYLKFLPAVDGSGFDADPLLVRCLRTEKTRSLNAVEGEVILRDSDLDPIADLPVLRLVEITYGEKTSDQRGEVVARLDPQEILPYVHQRYDDPAQVHDSVLLKDPAEVSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJJ7</accession>
    <name>C7QJJ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_2302</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 2,3-saturated acyl-CoA + NAD(+) = a (2E)-enoyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18177"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="2">
            <dbReference type="Rhea" id="RHEA:18179"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:10242"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mycolic acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786513.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2302"/>
    <dbReference type="EnsemblBacteria" id="ACU71220">
        <property type="protein sequence ID" value="ACU71220"/>
        <property type="gene ID" value="Caci_2302"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2302"/>
    <dbReference type="eggNOG" id="COG0623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_10_1_11"/>
    <dbReference type="OMA" id="GILDMIH"/>
    <dbReference type="OrthoDB" id="762291at2"/>
    <dbReference type="UniPathway" id="UPA00915"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050343">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU71220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27126" checksum="0BF4878FE5C27608" modified="2009-10-13" version="1">MGILEGKRIVVTGVLTDASIAFHAARIAQEEGAQVVLTAFPRPSLTQRIAKKLPNGDAPVIELDVTNAEQLAGLADNVKQHMDGVDGIVHSIAFGPQDALGGNFLNTPWESVATAVHVSAYSLKSVAMALLPLFPETGGSIVGLDFDAQVAWPGYDWMGVAKAALESTSRYLARELGSRGIRSNLISAGPLKTMAAKSIPGFEKFDGVWDERAPIGWDLTDMEPTARGIIALLSDWFPRTTGEVIHVDGGVHAMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK73</accession>
    <name>C7QK73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine--scyllo-inositol transaminase</fullName>
            <ecNumber evidence="2">2.6.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.50" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794876.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6293"/>
    <dbReference type="EnsemblBacteria" id="ACU75147">
        <property type="protein sequence ID" value="ACU75147"/>
        <property type="gene ID" value="Caci_6293"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6293"/>
    <dbReference type="eggNOG" id="COG0399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033332_7_1_11"/>
    <dbReference type="OMA" id="FFAGRWP"/>
    <dbReference type="OrthoDB" id="1722208at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047310">
        <property type="term" value="F:glutamine-scyllo-inositol transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080100">
        <property type="term" value="F:L-glutamine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="46063" checksum="1CF703C3BFEA8319" modified="2009-10-13" version="1">MSKLAAFGGTAAVPKHRRRSEWPLVEDDDRKAVITVLDGARLVSDTDGENPVAALEQDWARQFGYGHCVAVSNGTAALSLALSALGIGPGDEVIVPALSFIATGLAPVHQMAVPVFADIDPVTFNLDPDDLERRITARTAAIIPVHLHGAPADMDRIMAIAARHGIPVLEDAAQAPGATHRGRPVGSIGAAGVFSLQVSKNIPTCGEGGLLVTGDADLAAAMRRGRQFGEVIEAGRERDYVSYGLGWNHKMNGLQAAFTSSQLTRFEDYERARQANIGAFLARLAKLPGIQVPTALADTTHVWHILRFRFDPAAFGLDGVPPEALRSTLRRLLRAEGVPMSQYQLMPLPDQKVFVDRLGFGVGHHPWALTGAPGTVAGEGYPVTREVIADSLTIQKRHLHPEAGDLLALYADAFEKVWAAGDMVATLAKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKJ8</accession>
    <name>C7QKJ8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="9" type="ordered locus">Caci_8274</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796822.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8274"/>
    <dbReference type="EnsemblBacteria" id="ACU77097">
        <property type="protein sequence ID" value="ACU77097"/>
        <property type="gene ID" value="Caci_8274"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8274"/>
    <dbReference type="eggNOG" id="COG1570">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023625_2_1_11"/>
    <dbReference type="OMA" id="WPAVRFE"/>
    <dbReference type="OrthoDB" id="1371775at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="129"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="334"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="46042" checksum="1B37A792D8099892" modified="2009-10-13" version="1">MAMQSSAEEPIPVRAVSEAVAGWISRLGAIWVEGQLAQINKRPGSQMVYLVLRDPSADVSVQITTFRRVFEAVVPPLTEGARVIVYGKPDFYVPRSSFSIRGEEIRQVGLGELLARLEMLKAKLKAEGLFDPRRKKPLPFLPHCVGLITGRASAAERDVLENAKRRWPGVQFRVVNTDVQGPKAVPQILPALAQLDADPEVDVIIIARGGGSVEDLLPFSDEALIRAVGECETPVVSAIGHEPDSPILDLVADFRASTPTDAAKRVVPDVAEEMDRVAELRRNAWRSVARILEREAMGLASFRQRPVLASPYSMIDGRRNDLEELTRRARSSVGHRLDRASDDLGHTLARVRALSPMATLERGYSIVLAPSGHAVRSAEEVSEGDVLDIRFASGRVDAAVSEVFRADDASPDIASTEESPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL3</accession>
    <name>C7QKL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_8289</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8289"/>
    <dbReference type="EnsemblBacteria" id="ACU77112">
        <property type="protein sequence ID" value="ACU77112"/>
        <property type="gene ID" value="Caci_8289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8289"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_1_0_11"/>
    <dbReference type="OMA" id="IENDARG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="779"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="813"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="305"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="755"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU77112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="853" mass="85018" checksum="8FBCDD6999137B81" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVG7</accession>
    <name>C7PVG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0370"/>
    <dbReference type="EnsemblBacteria" id="ACU69323">
        <property type="protein sequence ID" value="ACU69323"/>
        <property type="gene ID" value="Caci_0370"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0370"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_5_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="115"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="224"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="55739" checksum="DED11516BD8BF659" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVS1</accession>
    <name>C7PVS1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphotriesterase-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="2">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786606.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2395"/>
    <dbReference type="EnsemblBacteria" id="ACU71313">
        <property type="protein sequence ID" value="ACU71313"/>
        <property type="gene ID" value="Caci_2395"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2395"/>
    <dbReference type="eggNOG" id="COG1735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054760_1_1_11"/>
    <dbReference type="OMA" id="CHMNPSH"/>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009056">
        <property type="term" value="P:catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001559">
        <property type="entry name" value="Phosphotriesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10819">
        <property type="entry name" value="PTHR10819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02126">
        <property type="entry name" value="PTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016839">
        <property type="entry name" value="PhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51347">
        <property type="entry name" value="PHOSPHOTRIESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="1 3">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601559-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601559-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="32417" checksum="0815726FD6A26972" modified="2009-10-13" version="1">MIRTVLGDIAADTLGVTDSHDHLFFASTKLPGQELDDPAAAEAELRAFAAAGGQALAQWTPIGLGRRAEELPALSEAAGVHIIAATGLHQAVHYSPEKLPRLLDGLAERFIAELGEGLRGDEEPDGPPLPPRAGLIKVAGDFHQVDRHASVVFEAAAAAHHATGSAVAVHLEGGTHPLGVLRTLHDRLGVPAGSVILGHLNRFPDPGPHREAAEAGAFLGFDGPSRANHATDWHLFDLLGSLVESGHADHVLLGGDTTSAAARAASGGGPGIPFLLTDIRARVQRDFGPEVAGAFFRRNPARAFDADWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT5</accession>
    <name>C7PWT5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PEBP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0098 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8369"/>
    <dbReference type="EnsemblBacteria" id="ACU77192">
        <property type="protein sequence ID" value="ACU77192"/>
        <property type="gene ID" value="Caci_8369"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8369"/>
    <dbReference type="eggNOG" id="COG1881">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083918_2_0_11"/>
    <dbReference type="OMA" id="DKAHRYI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981323" evidence="2">
        <location>
            <begin position="28"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="20511" checksum="AA92CEE4119B7030" modified="2009-10-13" version="1" precursor="true">MQKKTKIAIAGVASAAMFAAGAATAYAAVHDRFGYSPVRSGIPRDAAHFRVSSPDLTNGGVFPASEVCADTATAPRLNWAGAPAGTKSFAVEMFDPQAPTGSGFSHWRAWDIPASARTFGGQATPPAGTVVGQNDFGDAFFDAPCPPAGDVVHHYEIRVLALDTASIGLPSEGTSTAYSGYVLGQHIIGVAQMTVNAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX99</accession>
    <name>C7PX99_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69450">
        <property type="protein sequence ID" value="ACU69450"/>
        <property type="gene ID" value="Caci_0500"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0500"/>
    <dbReference type="HOGENOM" id="CLU_876297_0_0_11"/>
    <dbReference type="OMA" id="PHEFAIS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="34179" checksum="53BF17BC30930E2B" modified="2009-10-13" version="1">MKMVAWLAQHARPGVSWDRLALQAFDEDMPVPSEGIRRAFTRQIDKTRLPGGIALDSAPGTDRETWAVEAAETVTATGATMFRPLARIARIDSAVQSLLAAHAPWPPQEYADLDRRTDTDRTPAEITQMAVAAIIDPENYLPGSTIADVLAALLPEGQLSPMASFLEFSDLDATELTAAEWLGKNMAGSILEELRAAIAAADIAELRQAYRAAQACTRRTGELLNSVEAEIGAGTLGDACRAWVSAAAFGLPRIMLLVTARDRKPHEFAISAALLLWTNRMVSRLRSAFPGGFTALDEPLRQMVEGLSLAVLTGEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL3</accession>
    <name>C7PXL3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemerythrin HHE cation binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786759.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2548"/>
    <dbReference type="EnsemblBacteria" id="ACU71466">
        <property type="protein sequence ID" value="ACU71466"/>
        <property type="gene ID" value="Caci_2548"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2548"/>
    <dbReference type="eggNOG" id="COG5592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079417_2_2_11"/>
    <dbReference type="OMA" id="ERFDAKV"/>
    <dbReference type="OrthoDB" id="1701106at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="2">
        <location>
            <begin position="9"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="190" mass="21273" checksum="89FE4FED18C84822" modified="2009-10-13" version="1">MTDTDRRDVVEVLTHDHREVQEMFGKFETAGIGDARNVKALVDEVVIELSRHSVAEEEHLYPAVRRCVPNGNAMADREIREHADAEVLMRDLSRMEPNDEEFGPKLARLMATVREHIAEEEEQLFPALVAHSTQSELDELGRKVIAAKKAAPTRPHPSVPHSPPMDKVLAPALGLVDKVRDALTHRGTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN5</accession>
    <name>C7PXN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786781.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2570"/>
    <dbReference type="EnsemblBacteria" id="ACU71488">
        <property type="protein sequence ID" value="ACU71488"/>
        <property type="gene ID" value="Caci_2570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2570"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034737_0_0_11"/>
    <dbReference type="OMA" id="NICGNWE"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982590" evidence="1">
        <location>
            <begin position="25"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="571" mass="60819" checksum="AB54671BD6326A7E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP4</accession>
    <name>C7PXP4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786790.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2579"/>
    <dbReference type="EnsemblBacteria" id="ACU71497">
        <property type="protein sequence ID" value="ACU71497"/>
        <property type="gene ID" value="Caci_2579"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2579"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_11_11"/>
    <dbReference type="OMA" id="KMAARTH"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="419"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="503" mass="51619" checksum="EF282A2AE6F921D7" modified="2009-10-13" version="1">MKSSDSLTASRAQTADAVTLPELIEARADRDPERVALCVDGRDELTMGGWLSRARPVAAGLLGHAVRPGDRVGLLFADSAWLDYAVAALGVYLAGGAVVGMSARLGSAELTQRLSAVGAAGLIHGTGIDVPTGQGWSAPLPDLAAGSGSGPLSSRPAIAPDDLVEIIHTSGTTGPAKAVAVTHANLTFGRNAAMDQVAGPAGGVLTPVPLGTNACHSAILAALTSAATVHVLRRPDARSAAEAVARFQLPAAILPAPLARAMVAQGLAEQYLSGLRTLMLGSAPVHTVTANRLRALLPDTAVSIGYGSTEAAPAFTQLPSQDFEKHPGSLGLPRPGAEVRIVGPDGARAEPGSVGEIWLRCPGPQRSYYGRPMDDTFQDGWTRMGDLGSVGGDGYLSFFDRAADAVRAADGRLISTYSIEDALLEHPEVADAAAVADRSGPPGAVAAFVQPRTPGTPLPPDRLRGFLADRLSSAEVPARIVAVGELPRGPLGKVLKRRLGVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU7</accession>
    <name>C7PXU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4544"/>
    <dbReference type="EnsemblBacteria" id="ACU73407">
        <property type="protein sequence ID" value="ACU73407"/>
        <property type="gene ID" value="Caci_4544"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4544"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_5_2_11"/>
    <dbReference type="OMA" id="ARESEPH"/>
    <dbReference type="OrthoDB" id="1069752at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="45"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="22654" checksum="D88B90F2B1A1E6E2" modified="2009-10-13" version="1" precursor="true">MNRTQMAMISISQAADAAEPQDEATPGSASAPAARASMQALSAALRRERRRADLSLSEVARRADLSKSTLSQLESGIGNPSLETLWALCTALGIPFGQLFDPPPPRTQVIRAGSGAAVAAEQADYRVLLLATCPPGARRDVYRVEAEPGSVRRSDPHAPGVVEHVVVCAGRALVGVAEEPVELGPGDYIVYPGDVPHLFEALEPGTWAVTVSEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY10</accession>
    <name>C7PY10_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein serine/threonine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4609"/>
    <dbReference type="EnsemblBacteria" id="ACU73470">
        <property type="protein sequence ID" value="ACU73470"/>
        <property type="gene ID" value="Caci_4609"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4609"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045535_1_1_11"/>
    <dbReference type="OMA" id="GRIFPGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="166"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="41387" checksum="A6C0881CDF9F84EC" modified="2009-10-13" version="1">MVWLRRPDPRRDIAVSAAVVPGDPEAGGTPVTVTPAHSTWTQRLVPYLFIAVIVGADLATPKEVTFSSTLSVAPALSALLTRSVFQTICTSITAIGVSAVLYTYSLHVAGEVEVAACGAILVVTVVSAVSLGLVGRQSRMLANVRSVAETAQHVVLREVPPELTQVRTAVAYRAAAAEARIGGDLYEALSTRFGDRLLIGDVRGKGLPAVEAAADVLGVFREAAYTEADLSRVADRMHAMLARRPAGTEEFVTAVLLSVHPERPTVEVVNCGHPPPLLMRDGHVAALAPAEPGPPLGLFDLATPSGSASAPASARFAPGDTLLLYTDGTTEARDHTGRFFDLPAFLTGRPATSPAELTRQILTGLAAHAGARLDDDVALLVVRRKPYVPGPAAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY34</accession>
    <name>C7PY34_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-07" db="PDB data bank">
            <title>Crystal structure of glyoxalase/bleomycin resistance protein from Catenulispora acidiphila.</title>
            <authorList>
                <consortium name="Midwest Center for Structural Genomics (MCSG)"/>
                <person name="Filippova E.V."/>
                <person name="Minasov G."/>
                <person name="Shuvalova L."/>
                <person name="Kiryukhina O."/>
                <person name="Jedrzejczak R."/>
                <person name="Joachimiak A."/>
                <person name="Anderson W.F."/>
            </authorList>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS)</scope>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793223.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="PDB" id="4G6X">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.73 A"/>
        <property type="chains" value="A=1-131"/>
    </dbReference>
    <dbReference type="PDBsum" id="4G6X"/>
    <dbReference type="SMR" id="C7PY34"/>
    <dbReference type="STRING" id="479433.Caci_4633"/>
    <dbReference type="EnsemblBacteria" id="ACU73494">
        <property type="protein sequence ID" value="ACU73494"/>
        <property type="gene ID" value="Caci_4633"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4633"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_10_0_11"/>
    <dbReference type="OMA" id="GFVKKHD"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4" id="KW-0002">3D-structure</keyword>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="4G6X"/>
        </source>
    </evidence>
    <sequence length="131" mass="14009" checksum="978B790CAF7A46C2" modified="2009-10-13" version="1">MRIHLTNVFVDDQAKAESFYTGKLGFLVKADVPVGADRWLTVVSPEAPDGTQLLLEPSSHAAVTPFKEALVADGIPAASFAVDDIAAEYERLSALGVRFTQEPTDMGPVVTAILDDTCGNLIQLMQIAYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYC3</accession>
    <name>C7PYC3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_6567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795142.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6567"/>
    <dbReference type="EnsemblBacteria" id="ACU75413">
        <property type="protein sequence ID" value="ACU75413"/>
        <property type="gene ID" value="Caci_6567"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6567"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009266_0_0_11"/>
    <dbReference type="OMA" id="MVTGRCL"/>
    <dbReference type="OrthoDB" id="400741at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980450" description="FtsX domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="963"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1008"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="993"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1101" mass="112898" checksum="F24ADAA53FDCC506" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYP1</accession>
    <name>C7PYP1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS204/IS1001/IS1096/IS1165 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8543</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797088.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8543"/>
    <dbReference type="EnsemblBacteria" id="ACU77363">
        <property type="protein sequence ID" value="ACU77363"/>
        <property type="gene ID" value="Caci_8543"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8543"/>
    <dbReference type="eggNOG" id="COG3464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041900_0_1_11"/>
    <dbReference type="OMA" id="CPVHDHR"/>
    <dbReference type="OrthoDB" id="1128314at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029261">
        <property type="entry name" value="Transposase_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14690">
        <property type="entry name" value="zf-ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-ISL3" evidence="3">
        <location>
            <begin position="42"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="158"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="47303" checksum="C6487B4E1DA7AA59" modified="2009-10-13" version="1">MRNKSLWDALLGLADAVIESVDVDETSGQIVVQVRIKAAASRRCGRCLRRCPRYDQGTSRRRWRHMDAGVLMVWIVAEAPRVSCRDCGVVTCHIPWARAGAGHTADFDHHIAWLATNASKTTVATLARIAWRTVGAIITRVWADIEACTDRFANLSRIGIDEISYKKGQRYLTMVVDHDTGRLLWAGVGRDTETVDEFFDALGPERCVAITHVSADAAPWIAKSVRTHCPGAIRCADAFHVVAWATKALDTVRRQAWNTAAGRARDTNRTGRNSTGAARVLKGARWALWKNPEDLTTSQHHKLTWIAKTDPALWRAYLLKEGLRHVFKIKGAAGKTALDRWLSWAVRCRIPAFVELASTIKRNRTEIDNALDHNLSNALIESINTKIRRITRTAYGFTNPEALIALALLAHSGHRPQLPGRTTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ46</accession>
    <name>C7PZ46_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784897.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0666"/>
    <dbReference type="EnsemblBacteria" id="ACU69602">
        <property type="protein sequence ID" value="ACU69602"/>
        <property type="gene ID" value="Caci_0666"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0666"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_2_0_11"/>
    <dbReference type="OMA" id="NWGLMRE"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
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    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="25"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="31025" checksum="CFDA23314E993B30" modified="2009-10-13" version="1">MSSDSLAPAVPLGGHGPATALHDAWVVTLRNLRRMTRIPEMVVFSSIQPIMFVLLFAFVFGGAIPVPGAAGTTAYREFLLPGIFVQTLAFTAATTSVGLADDLHKGLIDRFRSLPISRSAVLAGRTTADWIQNLFVLLVMAICGLVVGWRIHDGVLKALAGFLLLMLFAYAMSWIGAVVGLSVRTVEAANTIGFIWIFPLTFLSNAFVPSRTLSPQWLQNVADWNPVSATVQALRSLWGNPDGYVSTAKMPWPIAHAPWVSLFWSLLILLVFVPMSVRKYRSVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ64</accession>
    <name>C7PZ64_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0685"/>
    <dbReference type="EnsemblBacteria" id="ACU69620">
        <property type="protein sequence ID" value="ACU69620"/>
        <property type="gene ID" value="Caci_0685"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0685"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078204_0_0_11"/>
    <dbReference type="OMA" id="CPGQRHA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="234" mass="24437" checksum="3454367ED59EFE52" modified="2009-10-13" version="1">MVTFTARADIETALADPLLVPLPAESGPEGSMAWLRATVARFAHGTVHARRRAYVEAELARIDGNELRRLATGRFGDDRTRVLRALARAMRLPELDDAAIDALCTVAANYFGGEDPAADDAVKLLLPLMRAGDPEQAANRVGILIQACDATAALIAAARDGSGKPPVQVMRRVALEATEVGTVEIPQGASVLLEVGPVGLTFGSGPRACPGRELALALAEGALAESPESLASPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ86</accession>
    <name>C7PZ86_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-associated region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786836.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2626"/>
    <dbReference type="EnsemblBacteria" id="ACU71543">
        <property type="protein sequence ID" value="ACU71543"/>
        <property type="gene ID" value="Caci_2626"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2626"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_20_2_11"/>
    <dbReference type="OMA" id="CWGSAPE"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="495"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="521" mass="54658" checksum="D0785DAB89BD1285" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA1</accession>
    <name>C7PZA1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2642"/>
    <dbReference type="EnsemblBacteria" id="ACU71558">
        <property type="protein sequence ID" value="ACU71558"/>
        <property type="gene ID" value="Caci_2642"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2642"/>
    <dbReference type="eggNOG" id="COG1023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024540_0_0_11"/>
    <dbReference type="OMA" id="PEYYQYD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004849">
        <property type="entry name" value="6DGDH_YqeC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00872">
        <property type="entry name" value="gnd_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="3">
        <location>
            <begin position="196"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="37715" checksum="B1B1A0A5C7EA8D97" modified="2009-10-13" version="1">MTQTEQGRHDVQLGMIGLGRMGADIVRRLMGEGHECVVYDHDPAAVEKLEHEGATGVSSLKDLAAQMTAPRAVWVMVPAGDVTTGVIEELAAVLDTDDIVIDGGNTYYRDDLQHAQTLAQHGVKHLDCGTSGGVFGRERGYCLMIGGEAEAVAHLKPIFETLAPGSEGAPRTPGREKTPLAEEEKGYLHCGPSGAGHFVKMIHNGIEYGMMASLAEGLNILRNADIGTRTQTGDAETAPMEHPEFYRYDIDTAAVTEVWRRGSVISSWLMDLTATALYQSPDLADFQGSVSDSGEGRWTSIAAIDEGVPAPVLTTALYSRFSSRRLDDFADRALSAMRKQFGGHAEKHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZD6</accession>
    <name>C7PZD6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786886.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71593">
        <property type="protein sequence ID" value="ACU71593"/>
        <property type="gene ID" value="Caci_2677"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2677"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_358914_0_0_11"/>
    <dbReference type="OrthoDB" id="2153438at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="780" mass="84009" checksum="AAF5F01DB93E43E2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZF1</accession>
    <name>C7PZF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786901.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71608">
        <property type="protein sequence ID" value="ACU71608"/>
        <property type="gene ID" value="Caci_2693"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2693"/>
    <dbReference type="eggNOG" id="COG0431">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_2_11"/>
    <dbReference type="OMA" id="VPEYNYG"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="21610" checksum="2B8036254710B0FF" modified="2009-10-13" version="1">MAKVTIIVASTRPSRIGHLIGDWVKQETEAFKGFDDVELVDLAVLNLPFMNEPHHPRLKRYVHQHTLDWSATVAAADAFLFVMPEYNYGYNAELKNAIDYLHQEWQYKPVGLVSYGGVAGGTRAAQMIKQVVTTLKMTPIFEAVPIPFVHQFITEQGTFQPNDIMTTALAATLEELLRVSEALRPLRQTPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZL4</accession>
    <name>C7PZL4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4668"/>
    <dbReference type="EnsemblBacteria" id="ACU73529">
        <property type="protein sequence ID" value="ACU73529"/>
        <property type="gene ID" value="Caci_4668"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4668"/>
    <dbReference type="eggNOG" id="COG2188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063236_2_2_11"/>
    <dbReference type="OMA" id="FAPRYFR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="27008" checksum="5CD0DC0A90730182" modified="2009-10-13" version="1">MSCLDSIYNSCMAASQPLYERIEKQLRRRLATAADGDPFPSEPRLAEEFGVSRMTVRAALAGLERDGLVERVPGRGSFVRKGAAHRPVGILLSFHDQALAEGKTPRSRVLHAELREASSQETAALYGFESEHAASVVAISRVRLFDDLPIAVEHAVFPAALSALLATDLETGSLHNALRRLGRTPTLGSSVLTARTAGDDAQELGVTPTTPMLVETRSIVDQDGSPLEYTVSSYVADRYALKVDFDVSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT2</accession>
    <name>C7PZT2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin dehydrogenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793326.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4736"/>
    <dbReference type="EnsemblBacteria" id="ACU73597">
        <property type="protein sequence ID" value="ACU73597"/>
        <property type="gene ID" value="Caci_4736"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4736"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_0_0_11"/>
    <dbReference type="OMA" id="MVEINFD"/>
    <dbReference type="OrthoDB" id="1017413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="296" mass="31443" checksum="71C660CFD46A487F" modified="2009-10-13" version="1">MDFLRPASWAEALAARAERPDAVPIAGGTDVMVELNFDRHRPGALIDLNRIPALRQWSRDADGTIRLGASVPYTRIIDELRTELPGLAMASRTVGSPQIRNRGGVGGNLGAASPAGDTHPALVATDAVIEVESAARGVRTIPSTEFYLGVKRNALAADELIKAVLLAPAKGPQQFSKIGTRNAMVIAVCSFAVALDVGARKVGAGIGSAAPTPRRAFEAELFAADALPWDGRGDLDPRVARRFGELVAAAAAPIDDVRGTAAYRRHALSVMARRTLTWAWAEHQSSQTETEETDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q007</accession>
    <name>C7Q007_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6654</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795229.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6654"/>
    <dbReference type="EnsemblBacteria" id="ACU75500">
        <property type="protein sequence ID" value="ACU75500"/>
        <property type="gene ID" value="Caci_6654"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6654"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605054_0_0_11"/>
    <dbReference type="OMA" id="ALAWIPD"/>
    <dbReference type="OrthoDB" id="1332872at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982379" evidence="6">
        <location>
            <begin position="19"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="5"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="452" mass="47206" checksum="1D8E4BE9482401E8" modified="2009-10-13" version="1" precursor="true">MRRTAAALLALTVGCVLADSAVVTLALPEILERLHTTVGQVAWVLIAFNLVLAVVVRPAAWFFKRLDPAILSAVGIAVFAGASALCAVAGSLDVLIVARSVQAVGGAFAVVGCLQLLVEELSERRGTAWWIAAGVFGTAVGPVAGGLLTDAFSWRSIFVVQVPIAVLAVPAALVKRRRKGQELAEDTPKHRVQIGPNIALALLSAALTAALFLFVLLLVDGWRRSPAIAAVTVSVIPLAALFSRPLSRKLRAGPTAETMSGCLLIAGGLAGLALLPSAELGWTIAPQALVGLGLGLTLDPLTLQAMDGRMPHFLHGSWTIAARHAGVVLGLAILTPVFTADLQNAQPPAKDAITALVLDAPLTPEDKISIAGGLSDQLKEENGRVPDLDPAFAKLHVSAIEKPATVQLERDLNDQLQRAATHAFRNAFLIGAALALTALLSLIPLRRRGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0G7</accession>
    <name>C7Q0G7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetracyclin repressor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797224.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8685"/>
    <dbReference type="EnsemblBacteria" id="ACU77500">
        <property type="protein sequence ID" value="ACU77500"/>
        <property type="gene ID" value="Caci_8685"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8685"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069543_0_2_11"/>
    <dbReference type="OMA" id="PEVIWAR"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="24500" checksum="D2A3CEB5C6E8B578" modified="2009-10-13" version="1">MDPETLWSERRHHRGRPPAHTREAVVATAVGVADAEGLSALTMRRVATALGSGTMSLYTYVSERDALLELMIDAVTGEQPLPLPTGDWRADLAAFAREQRALMHRHPWLPVALTGRRTLGPNTLRALDHALALLAPSGLPPRARTEAFALVSGFVASHVGYEAAQQQALGRTDDVREFVASNARYLAAAVESGAYPHLAEAMAESGAETPEADETFERMLAQVISGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Q1</accession>
    <name>C7Q0Q1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine exporter protein (LYSE/YGGA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69679">
        <property type="protein sequence ID" value="ACU69679"/>
        <property type="gene ID" value="Caci_0744"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0744"/>
    <dbReference type="eggNOG" id="COG1280">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079569_3_0_11"/>
    <dbReference type="OMA" id="LAVRHWI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="22170" checksum="31E4BF7F47B72CDB" modified="2009-10-13" version="1">MGCMDGSVLHALVSFALVAGLVTVIPGLDTAVVLRSALVLGRGQAFGAAFGVTFGALVWGAAAATGVSVLLTASHAAYTGLRVVGALYLLWMGMGMVRAAWRGELSQGSEQVPDTGLVRAFLRGAGTNLLNPKVGAFYIAVFPQFMPVHVSHLAMGLGLAGVHDLEAMVWFSVLILGAHRARAWFAKRRVKRALDAVTGTVLVGFGVELALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0W8</accession>
    <name>C7Q0W8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0811"/>
    <dbReference type="EnsemblBacteria" id="ACU69746">
        <property type="protein sequence ID" value="ACU69746"/>
        <property type="gene ID" value="Caci_0811"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0811"/>
    <dbReference type="HOGENOM" id="CLU_629611_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982680" evidence="3">
        <location>
            <begin position="29"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="43389" checksum="D5C7345814769D61" modified="2009-10-13" version="1" precursor="true">MRIQRSARSVVAGVAGTCLVTVAMGVLAATPAQARGSATLTLGPNNGAPGSSFTASFHMSAPGGPNACLGATVTFTFDATALGTAGLDQSCAATVSLPVPPAATNGAHKVKAVASGGASATANATFTVTGSTATPTTTAPTKTAPPSWSNSTTPYPGWTAPPFASQVIPTSTGPCDTSGPHATAPDKAFLQIPAYSVGAHPANNGSKVIVEPATGALPLVSVGPGGMIPPQLGDGRHPYQNLELMETIDPNVSSKLRLAAAAGEPFGCLHVESFGGTGSGYSYLSFALKDATVISVQDANADGSLFETAAPSVPSASTPAPAPGGKTTGTAKGNAPAAPATPTPPAPKAKFEKVVLGYSSLSWEYQEAAGGAQAPIHRGAGTIVPPAPPAPLSYSNLVFAFGGLVAAAVALMFAYHSRRRDLARRQRRRKASHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q133</accession>
    <name>C7Q133_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787001.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2795"/>
    <dbReference type="EnsemblBacteria" id="ACU71708">
        <property type="protein sequence ID" value="ACU71708"/>
        <property type="gene ID" value="Caci_2795"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2795"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129722_1_0_11"/>
    <dbReference type="OMA" id="NIYKYAT"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="19"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14423" checksum="DF8CBBDC1A7FD2E9" modified="2009-10-13" version="1">MGPGTAAGPIRTQPIAASDDVVRARQLARTLAVECGLSLVEQTKLVTAASELARNTLVYGGGGRMDGEMLKRPGGRGVRLTFADEGPGIPDTDLALRDGWSSGTGMGLGLSGARRLVDEFDLNTGAGQGTIVTVIKWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q170</accession>
    <name>C7Q170_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2836"/>
    <dbReference type="EnsemblBacteria" id="ACU71745">
        <property type="protein sequence ID" value="ACU71745"/>
        <property type="gene ID" value="Caci_2836"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2836"/>
    <dbReference type="eggNOG" id="ENOG5032T0J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074053_0_0_11"/>
    <dbReference type="OMA" id="CQCECGN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="220" mass="25018" checksum="F9953CAA9F99D494" modified="2009-10-13" version="1">MPIRIGDKYERWTVVEVISKREVACRCDCGTERSVQIGNLRQGKSRSCGCLQHTVAIAPGDRFGRLTILAAPTRLAIRCRCDCGTEMTTKAIHLVAKAVLSCGCLRREVTRTRGRKNRTHGLSSHELYGTWTRMVARCTNPKSGDYSYYGGRGIRVHEPWLRVAVFIPEIVSLIGERPKGLTLDRIDVNGNYEPGNVRWATRLEQSRNQRPRRQNQQRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1P3</accession>
    <name>C7Q1P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6749"/>
    <dbReference type="EnsemblBacteria" id="ACU75594">
        <property type="protein sequence ID" value="ACU75594"/>
        <property type="gene ID" value="Caci_6749"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6749"/>
    <dbReference type="eggNOG" id="COG4932">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_380701_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="727" mass="72498" checksum="9D6E9A63E969DDAA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1R3</accession>
    <name>C7Q1R3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795343.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6769"/>
    <dbReference type="EnsemblBacteria" id="ACU75614">
        <property type="protein sequence ID" value="ACU75614"/>
        <property type="gene ID" value="Caci_6769"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6769"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_11"/>
    <dbReference type="OMA" id="THWTNIP"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="418"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="54507" checksum="B9DE9EDFB7AAB73D" modified="2009-10-13" version="1">MTSLSLASILAEPAWRRPDSVALIEGDRRYTFAELWDQVLRQAGALVEQGVRPGDKVALMCPNTAEFPRAYYAILAAGGVVVPVHLLLTADEAETVLRDSGASLVIAHAMCAETAAKAAENIGVKLLTAGSGGGLEELTEQATPLATFLTRKPEDPAVIFYTSGTTGTPKGAVLSHLNLVLNATTDAYDARDDIRRDDIVLASLPLFHTFGQTVSMNASWRLGNTVVLLPRFDPDAAIALMVQERVTTFHGVPTMYVTLIEAAARAERMPTLRRCVSGGASLPVPVLERFEAAFGAKVLEGYGLSETSPVASVNQLSIGTRAGTVGHPLWGVDVEIADPDVPEAIRLLPRGELGEIVIRGHNVFTGYLGRPEATAAAVVDGWFRTGDLGRRDAEGFISIVDRTKDLIIRGGFNVYPREVEDALLRMPGLTEVAVIGVPDDVHGEEIVAVVVAGDAVPPAEEILAYGNEHLGRHKYPRRVEFVDALPLGPSHKVLKRELRDRFGKPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V4</accession>
    <name>C7Q1V4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosidase PH1107-related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6814</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 130 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795383.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6814"/>
    <dbReference type="EnsemblBacteria" id="ACU75655">
        <property type="protein sequence ID" value="ACU75655"/>
        <property type="gene ID" value="Caci_6814"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6814"/>
    <dbReference type="eggNOG" id="COG2152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046648_0_0_11"/>
    <dbReference type="OrthoDB" id="1622507at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007184">
        <property type="entry name" value="Mannoside_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34106">
        <property type="entry name" value="PTHR34106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04041">
        <property type="entry name" value="Glyco_hydro_130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="343" mass="37315" checksum="0A00840EDB8C8D4D" modified="2009-10-13" version="1">MLMKRHPANPILRRNPDQPWEAGSVLNGTVVRGADGVIHMLYRATNGVEFSTAGEYVSSIGIADSTDGVRFIRRPEPLIVADQPYEHGLGCEDPRVVFLDGEYYIYYTAVEGVPPDIKVRIALATTPDLRAETVAKHGIVGPQGAPSKAATLFPEPVGGKYLWFFTWCSDTPGAAILHTTFDDLAAVKNPPRGHVAAAVDAYDDTAVLIPGDRAELAKKRVRRGPELGAPPIRTDAGWLFFYCNSDSEEEPEWQISAALLDLERPWQVIARTPAPLLTPQTEVELTGVVNRVTFPSGALVIDETVHLYYGSGDQGICLATCELDALLEHLQSFPVKEEGPCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2A9</accession>
    <name>C7Q2A9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inner-membrane translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8833"/>
    <dbReference type="EnsemblBacteria" id="ACU77646">
        <property type="protein sequence ID" value="ACU77646"/>
        <property type="gene ID" value="Caci_8833"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8833"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006313_4_2_11"/>
    <dbReference type="OrthoDB" id="1456257at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="637" mass="65915" checksum="6D97E859601FA0E3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2M3</accession>
    <name>C7Q2M3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ordered locus">Caci_0933</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0933"/>
    <dbReference type="EnsemblBacteria" id="ACU69865">
        <property type="protein sequence ID" value="ACU69865"/>
        <property type="gene ID" value="Caci_0933"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0933"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_3_2_11"/>
    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="12471" checksum="7D504FAAFE120735" modified="2009-10-13" version="1">MSSKFADRSVLARDIIIKPVVSEKSYALLDQNTYTFIVHPDTNKIQIREAVEEIFDVKVLSVNTINRQGKRKRTRFGVGKRKDTKRAIVTVDPNPGDGKKGRIELFGGPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2W3</accession>
    <name>C7Q2W3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787148.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2946"/>
    <dbReference type="EnsemblBacteria" id="ACU71855">
        <property type="protein sequence ID" value="ACU71855"/>
        <property type="gene ID" value="Caci_2946"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2946"/>
    <dbReference type="HOGENOM" id="CLU_2583270_0_0_11"/>
    <dbReference type="OrthoDB" id="1370308at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024064">
        <property type="entry name" value="FdhE-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144020">
        <property type="entry name" value="SSF144020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="80" mass="8795" checksum="C1CC14FD35E3CB69" modified="2009-10-13" version="1">MTTIAKQVNIRTANRTSALALLVIQAKFAAIAEVEADEFHTCPMCGHATAELFTRIDNRDNAEIEICETCADTEDVSYCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3I1</accession>
    <name>C7Q3I1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795474.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6909"/>
    <dbReference type="EnsemblBacteria" id="ACU75746">
        <property type="protein sequence ID" value="ACU75746"/>
        <property type="gene ID" value="Caci_6909"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6909"/>
    <dbReference type="eggNOG" id="ENOG503375I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133158_0_0_11"/>
    <dbReference type="OMA" id="GVHECDL"/>
    <dbReference type="OrthoDB" id="2061619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="169" mass="18808" checksum="69616369B8042513" modified="2009-10-13" version="1">MYFEDLTAYGYRDGPDVVSLHDRIDRSSPPFPVVEPTASRVSVGWLGGHRRFVRRTRFPTGQSSHDVIDALIDVIAAQAVNVTRGFHRCEYCPAKKADAQLEFVHRGRTIPLGSSEIRVPAADASVFAAPTLIAHYVRDHRYCPPPAFTDVLMAFRHSTADLARGWFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3K0</accession>
    <name>C7Q3K0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795493.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6932"/>
    <dbReference type="EnsemblBacteria" id="ACU75765">
        <property type="protein sequence ID" value="ACU75765"/>
        <property type="gene ID" value="Caci_6932"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6932"/>
    <dbReference type="eggNOG" id="COG4043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139906_0_1_11"/>
    <dbReference type="OMA" id="WKENRYG"/>
    <dbReference type="OrthoDB" id="1789270at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016645">
        <property type="entry name" value="UCP016134"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016134">
        <property type="entry name" value="UCP016134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="17"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="13925" checksum="BB3E99CC9A30BC0E" modified="2009-10-13" version="1">MTTRPTTDTTFCTYEMNLYRRYFDMVASGRKTIEVRVHYPKLRSLTTGDHIRFIYDTDSVLTRVKRVARYTSFEQMLDAEDAARVNPDSPHEQQLVDMRRIYSPEKEALGVLAIEIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R6</accession>
    <name>C7Q3R6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8861"/>
    <dbReference type="EnsemblBacteria" id="ACU77674">
        <property type="protein sequence ID" value="ACU77674"/>
        <property type="gene ID" value="Caci_8861"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8861"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040940_3_1_11"/>
    <dbReference type="OMA" id="WERPWDR"/>
    <dbReference type="OrthoDB" id="1623169at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="25566" checksum="DEC257DA1A81DD1B" modified="2009-10-13" version="1">MSVAHDMDIPIADPLPDWLLPLARAAESATGLGPRFKRPADLDGEPRRSAVLILFGEDPAHGPDVLFVERAKTLRHHPGQPAFPGGAVDPGEGPVATALREANEETDLDPAGVQVFGILPDQYVFPSDFLVTPVLGWWRSPSPVRVRDVREVASVHRIAVSELVDPANRLRVGSPSGTSSPAFEAGPLLIWGFTAALLDGVLKAGGWELPWDTERVEPLPQEVVALAVRSRAAPGGEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q455</accession>
    <name>C7Q455_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ordered locus">Caci_0984</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785209.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0984"/>
    <dbReference type="EnsemblBacteria" id="ACU69915">
        <property type="protein sequence ID" value="ACU69915"/>
        <property type="gene ID" value="Caci_0984"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0984"/>
    <dbReference type="eggNOG" id="COG0736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089696_0_0_11"/>
    <dbReference type="OMA" id="LGVRSWH"/>
    <dbReference type="OrthoDB" id="1893660at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12182" checksum="EDF753FE9ECC0C62" modified="2009-10-13" version="1">MILGVGIDVVDVDRFAASLARTPALREKLFTPAERERGTASLAARFAAKEALAKSLGAPRGLRWHDGEVVTLPDGRPELRVTGTVAALAESRGIRVFHVSLSHDAGIASAVVIAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4K5</accession>
    <name>C7Q4K5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper resistance protein CopC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3065</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787267.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3065"/>
    <dbReference type="EnsemblBacteria" id="ACU71974">
        <property type="protein sequence ID" value="ACU71974"/>
        <property type="gene ID" value="Caci_3065"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3065"/>
    <dbReference type="eggNOG" id="COG1276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023176_0_0_11"/>
    <dbReference type="OMA" id="IVSWPPR"/>
    <dbReference type="OrthoDB" id="1753926at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046688">
        <property type="term" value="P:response to copper ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032694">
        <property type="entry name" value="CopC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007348">
        <property type="entry name" value="CopC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008457">
        <property type="entry name" value="Cu-R_CopD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008620">
        <property type="entry name" value="FixH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34820">
        <property type="entry name" value="PTHR34820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04234">
        <property type="entry name" value="CopC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05425">
        <property type="entry name" value="CopD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05751">
        <property type="entry name" value="FixH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982519" evidence="9">
        <location>
            <begin position="47"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="CopC" evidence="10">
        <location>
            <begin position="45"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CopD" evidence="11">
        <location>
            <begin position="355"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU71974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="578" mass="59482" checksum="2EE75FC36063A06C" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S8</accession>
    <name>C7Q4S8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PfkB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793605.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5016"/>
    <dbReference type="EnsemblBacteria" id="ACU73876">
        <property type="protein sequence ID" value="ACU73876"/>
        <property type="gene ID" value="Caci_5016"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5016"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_11"/>
    <dbReference type="OMA" id="CIGIEPL"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="9"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="321" mass="33143" checksum="A6D5BC71079A8422" modified="2009-10-13" version="1">MTAPSCLDVLTIGETMAALRADGAIRLGSAMTLSPAGAESTVAIGLARLGHRAGWVGRVGADEFGELILRTLRAEGVDLTHARVDPDGRPTGVMAREHRVGSLIRVSYHRSGSAGSALEPGDVLPALEGGARILHLTGITPALSPSAAEAVRAAARRARELGVRVSFDVNYRSRLWSPERARDVLLPLAELADVLIASSDELHLVSPNPASDEAGAAAAILARGTREVVLTRGGDGASVITAEGTMSVPVRLVPVVDVVGAGDAFVAGYLSALLDDLPVEDRLHRAATTGAFAVATAGDWEGLPTRADLALLDEPSGSTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4V3</accession>
    <name>C7Q4V3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">o-succinylbenzoate synthase</fullName>
            <shortName evidence="3">OSB synthase</shortName>
            <shortName evidence="3">OSBS</shortName>
            <ecNumber evidence="2 3">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menC</name>
        <name evidence="5" type="ordered locus">Caci_5041</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793630.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5041"/>
    <dbReference type="EnsemblBacteria" id="ACU73901">
        <property type="protein sequence ID" value="ACU73901"/>
        <property type="gene ID" value="Caci_5041"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5041"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_4_11"/>
    <dbReference type="OMA" id="GRQDEWF"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03317">
        <property type="entry name" value="NAAAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01933">
        <property type="entry name" value="MenC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010197">
        <property type="entry name" value="OSB_synthase_MenC_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48073:SF5">
        <property type="entry name" value="PTHR48073:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01928">
        <property type="entry name" value="menC_lowGC/arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="4">
        <location>
            <begin position="142"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="369" mass="39287" checksum="FBED6DBC5FF82360" modified="2009-10-13" version="1">MKLERVELRRIGIPLATPFRTSLGLELDRDILILRADTSEGPGWGECVAMPEPGYSEEYLDGAAHVIQRFLLPAVAALDDLTPARAAAAMAAFPGNPMAKATVEMAVMDAWLRARRSSYADHLGAVRSTVESGVSVGIADTIDQLLAEVSGYVDQGYRRIKLKIEPGWDLEPVRAIRERFPDIALQADANAAYTFADARHLAALDAFDLVMLEQPLGTADVRDHAALARMLRTPICLDESITSARSAADAIALGACAIVNIKAGRVGGYLEARRIHDVCAAHSVPVWCGGMLETGLGQAANLALAALPGFTMPADIAPSARYFATDVTAPITMSEGRIAVPDGPGLGLDPIPEILEGYTTDVVTITRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5I8</accession>
    <name>C7Q5I8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77799">
        <property type="protein sequence ID" value="ACU77799"/>
        <property type="gene ID" value="Caci_8986"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8986"/>
    <dbReference type="HOGENOM" id="CLU_753756_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="367" mass="40280" checksum="1D45F69B166D8154" modified="2009-10-13" version="1">MTRRRTTPRDSVGDSAVSGAAAINFWTLLTEASGAEKVALHAGPELAEPFKHFNAAVGNYRNAADVACYLYGINDGVPKSYEETAVRFNTSVKVVKSVEGAALDLIRMLRNARSPGSNDDQPDVLDELRDLAAIRYFGPRGPRPLRKGEDRPDDPWNGQSCLVCNSPLPYAGTGRPRSTCSSRCRQRLYRLRKNGIQPSQISPEPDHVPAAAERPRTHWAPRHQTAGYVSFEEAAQDFRDKVAELQVAVAKPYSLMVGHQVYAVWESGWYFSTLLRDQRPPTTDAASSRAVLTALARIIDELGRLAEADDDYGRAQWHNSTQQKAVSALAKFARIATKIVGLCDDLSRARSNLPRTDYGGAGTTPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q651</accession>
    <name>C7Q651_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Secretion protein snm4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EccD/Snm4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3148"/>
    <dbReference type="EnsemblBacteria" id="ACU72057">
        <property type="protein sequence ID" value="ACU72057"/>
        <property type="gene ID" value="Caci_3148"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3148"/>
    <dbReference type="eggNOG" id="ENOG502ZAY5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028325_1_0_11"/>
    <dbReference type="OMA" id="REDWDFE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044049">
        <property type="entry name" value="EccD_transm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006707">
        <property type="entry name" value="T7SS_EccD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024962">
        <property type="entry name" value="YukD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19053">
        <property type="entry name" value="EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08817">
        <property type="entry name" value="YukD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017804">
        <property type="entry name" value="Secretion_EccD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03920">
        <property type="entry name" value="T7SS_EccD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="EccD" evidence="5">
        <location>
            <begin position="119"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="484" mass="48959" checksum="7433EFFC311B4A31" modified="2009-10-13" version="1" precursor="true">MAASHGSGAGALTMASSASAGEASAPNRMTWARRATVVSPRARVDVALPVQSTFAELVPELVRLSDAQRHIGPGHTGWVLTRLGGAPIAPELTVAASGLRDGDVLYLVPRERQGAPLLFDDVVDAIASASERSDGAWRPSTAHRVGAAAGAVALAGATMLLFALLSGKAAAPAVLGGALIALLAAGGVLARLAHDRRAAIACVAAGLPAAVMAGVSAAPPHQLWPLHGGSAALGLAALAVYGAVAIVTVKHYSAWFGALAGAAVLGGGTAAVVGLADVTAAHAGVVLAVFATALAAGAPILSMRLGRLPLPRVPSDITAFRENEEPTLGPDVLDQTTTAQRMLTGLLAALGLSAVSGAVAALKAPGTWPVVFVSLLSVVWMLRSRAYTDTVQRVLLVGSGLAALTWLAGSLVVRHEQALLLAGVSVLALAGLGCFVYARHAGQGRHSPYWTRFMDVAEFLSVVALLPIAGVALGVYQHLGHIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q686</accession>
    <name>C7Q686_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787385.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3184"/>
    <dbReference type="EnsemblBacteria" id="ACU72092">
        <property type="protein sequence ID" value="ACU72092"/>
        <property type="gene ID" value="Caci_3184"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3184"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_4_2_11"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10159" checksum="C8F237892BCDC74E" modified="2009-10-13" version="1">MTDYVFSFRVPADYAPNAETPAEWQAWFGELGPALVNIGHAVTEHAVLGEIGGAGSRFVAYSIVAAEDLDAALALAKDCPVLRVGGGVEVGPVMAVAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6R5</accession>
    <name>C7Q6R5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UmuC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5241"/>
    <dbReference type="EnsemblBacteria" id="ACU74100">
        <property type="protein sequence ID" value="ACU74100"/>
        <property type="gene ID" value="Caci_5241"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5241"/>
    <dbReference type="eggNOG" id="COG0389">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026357_0_0_11"/>
    <dbReference type="OMA" id="HRPECAW"/>
    <dbReference type="OrthoDB" id="658705at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="398"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="535" mass="56119" checksum="B61201278341BB4A" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6T5</accession>
    <name>C7Q6T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7118"/>
    <dbReference type="EnsemblBacteria" id="ACU75948">
        <property type="protein sequence ID" value="ACU75948"/>
        <property type="gene ID" value="Caci_7118"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7118"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087580_2_1_11"/>
    <dbReference type="OMA" id="TGRQRWW"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="20561" checksum="78742096647FBAF7" modified="2009-10-13" version="1">MPAKPIRRMDVRSLRALAHPLRMDILDVLKADGPATSTTLADRLGESTGTLSWHLRLLAEHGFIEEDVERGTKRERWWHAVEERQVLDPADMPGERALSIYLGTIVRQCFERAERYVAEDWSEEWQSAATLSDWQDLQLAPDRLAALNRDLFAVVDRYVSEPQDPDGAPVSVQIQSFPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q740</accession>
    <name>C7Q740_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7224"/>
    <dbReference type="ESTHER" id="catad-c7q740">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76053">
        <property type="protein sequence ID" value="ACU76053"/>
        <property type="gene ID" value="Caci_7224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7224"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_745208_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="90"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="36257" checksum="CF11FD821DC93454" modified="2009-10-13" version="1">MATDEVDEQHDAIDVEHYLAADLPRRPWHRRVLRRTAKTVAVVFVTLTMLSVPYNAYTAGTVAPPPGLTYVTADGIHTRYETWGTSGSPIVLVHGAVEDSDTWQDLAAVLAKDHRVYALDLTGSGYSRRVSPYTPQHMAAQLTGLVTALHIDRPVLVSHSSGAAVAAEAVLESPHTYSGLMFLDGDGLPIPSPGVTWVLGPLRTSVLRLVLRSDWAIRTIYASECGPSCPRLDAAGVERFRRPYQVAGAEQGLWDTLDTVGGPGLPASRLSQLTQLCLPKAVTFGAQDSMFAANAPQSVAANIGAPAPTVIQGAHHLSLVSHPAQVAASVEALVARAEPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q787</accession>
    <name>C7Q787_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cellulose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785469.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1250"/>
    <dbReference type="EnsemblBacteria" id="ACU70175">
        <property type="protein sequence ID" value="ACU70175"/>
        <property type="gene ID" value="Caci_1250"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1250"/>
    <dbReference type="eggNOG" id="COG2268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073070_0_0_11"/>
    <dbReference type="OMA" id="LHLETQT"/>
    <dbReference type="OrthoDB" id="937807at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="35597" checksum="45BF293AB5AD987F" modified="2009-10-13" version="1">MSDMHSPHGFEQVRRGYDPVQVNDRITKLIAERDAAHSRSTSMEKRIEELHLENQTVQAQLADSEPSYAGLGARVEKILRLAEEEAKDLREEARRAADAHRELADQAAMKVRTDAEQYAKDRKAKADEEAVRIVEKAKDDANQVRATAAKDAATKREEAEALFEETRAKAAAAATDFETKLAKRREQSERDLAARQAKAEKRLAEIENRAEQLRLEAEKMRTDAERRARSTIETAQRQADDIIADARSKTDRIRSEAERELAALTHRRDSINAQLHNVREMLATLTGGAVNVNALAGLTEAEEELEKDDEASIPAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q799</accession>
    <name>C7Q799_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF3817 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1262</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1262"/>
    <dbReference type="EnsemblBacteria" id="ACU70187">
        <property type="protein sequence ID" value="ACU70187"/>
        <property type="gene ID" value="Caci_1262"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1262"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120964_3_3_11"/>
    <dbReference type="OMA" id="FWADAWN"/>
    <dbReference type="OrthoDB" id="1709780at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3817" evidence="8">
        <location>
            <begin position="14"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="102" mass="11264" checksum="FD520084EBF1FC61" modified="2009-10-13" version="1">MTTVVETTAEDTKLARFRVVSLAEGVSFLILLGIAMPLKYAAHMPAPTMVFGMIHGLLFLAYLALAYAVKQTQDWDAKRFLVVLVASVLPTGPFWLHKSLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7H3</accession>
    <name>C7Q7H3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate dehydrogenase (Acetyl-transferring)</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3259</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3259"/>
    <dbReference type="EnsemblBacteria" id="ACU72166">
        <property type="protein sequence ID" value="ACU72166"/>
        <property type="gene ID" value="Caci_3259"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3259"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_5_0_11"/>
    <dbReference type="OMA" id="LGYEMPC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="entry name" value="DH_E1"/>
    </dbReference>
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        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ACU72166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="35575" checksum="DE0BD6044A356E3C" modified="2009-10-13" version="1" precursor="true">MRSALPGSVAPASASAASPSPDPAALYRTVRLIRRFEERAVELVRAGEVFGGIHPYTGQEAIAAGTCGALRADDLITSTHRGHGHVLAKGADPARMMAEIAGRATGLNRGRGGSMHAADFGVGILGANAIVGAAAPIATGAAWAARCAGSDRVVVTYFGDGAVSQGVVLETFNMAALWRAPVIFVCENNGFATTTRTQDAVAGSITGRAEAFGIPAERVWGMDPEAVYAATARAVARARSGEGPTLLECETYRYDAHHTWEHAARPRYRTPEEVELGRSVDPLDIQGARIDAGVRARIDAEVDVLLDEAVRFALESPRPDPATALDFLYADGTTARAGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q874</accession>
    <name>C7Q874_CATAD</name>
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        <submittedName>
            <fullName evidence="8">MMPL domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7233</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7233"/>
    <dbReference type="EnsemblBacteria" id="ACU76062">
        <property type="protein sequence ID" value="ACU76062"/>
        <property type="gene ID" value="Caci_7233"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7233"/>
    <dbReference type="eggNOG" id="COG2409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005108_1_1_11"/>
    <dbReference type="OMA" id="FAYRRKG"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="199"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="331"/>
        </location>
    </feature>
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        <location>
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            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="639"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="45"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="438"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="742" mass="77722" checksum="B4E60D72C9B60962" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B4</accession>
    <name>C7Q8B4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribonuclease, Rne/Rng family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7273</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7273"/>
    <dbReference type="EnsemblBacteria" id="ACU76102">
        <property type="protein sequence ID" value="ACU76102"/>
        <property type="gene ID" value="Caci_7273"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7273"/>
    <dbReference type="eggNOG" id="COG1530">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_258824_0_0_11"/>
    <dbReference type="OMA" id="RDWNDSR"/>
    <dbReference type="OrthoDB" id="1209444at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
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        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="S1_domain"/>
    </dbReference>
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        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="719"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="665"/>
        </location>
    </feature>
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        <location>
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            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1200"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1299"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="616"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1098"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1334" mass="140833" checksum="8BD260EB83DF3556" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8B8</accession>
    <name>C7Q8B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795834.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7277"/>
    <dbReference type="EnsemblBacteria" id="ACU76106">
        <property type="protein sequence ID" value="ACU76106"/>
        <property type="gene ID" value="Caci_7277"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7277"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085376_5_2_11"/>
    <dbReference type="OMA" id="AGRFEWY"/>
    <dbReference type="OrthoDB" id="1069752at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="189" mass="19939" checksum="AF0287EA49A632E3" modified="2009-10-13" version="1">MGDGTPSDFATQIGARIRRLRLERGVSLSALARDAAVGKATLSGLEDGSRGNPTIETLYAIAGRLGVPIGALLPDPPHPGEKPLETIHGTAVSASLLETFSDADADTELFRLHIRPGHEQLSPAHPPGTVEYLTVFTGTARVGRPDALLTVPPGAHVSWTADVPHTYTAISDDDVYASLLIRTPRPPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8J9</accession>
    <name>C7Q8J9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785558.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1341"/>
    <dbReference type="EnsemblBacteria" id="ACU70264">
        <property type="protein sequence ID" value="ACU70264"/>
        <property type="gene ID" value="Caci_1341"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1341"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_11"/>
    <dbReference type="OMA" id="HYEIDLG"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="31606" checksum="F38664A159A71386" modified="2009-10-13" version="1">MTRLPDLDALQLLVAVADTGSLGKAAARTGISQPSASARMATLERRLGLKLLARTTSGSRLTSDGAMVTDWARRVLEQAEALVEGAEALRTHADERLAVAASLTIAEHLMPTWLIELRQLRPAIRVGLTVENSHQVVAALRAGQVELGFVEGPWVPRDLHSAVVGRDRLVVVVAPAHPWARRKEPLTAAELAAEPLLLREPGSGTREVLEAALSAHDGPAVPLIELGATAPLRSAALSGSGPAVLSVLAVAEDIAAGRLAEVPLAEDVALRRTLRAVWVRGRELNEAAGWLVQVARGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L5</accession>
    <name>C7Q8L5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785574.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1357"/>
    <dbReference type="EnsemblBacteria" id="ACU70280">
        <property type="protein sequence ID" value="ACU70280"/>
        <property type="gene ID" value="Caci_1357"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1357"/>
    <dbReference type="eggNOG" id="ENOG50339F5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090342_1_0_11"/>
    <dbReference type="OMA" id="YFWASAN"/>
    <dbReference type="OrthoDB" id="1864489at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025333">
        <property type="entry name" value="DUF4239"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14023">
        <property type="entry name" value="DUF4239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26962" checksum="54EB83136EF70808" modified="2009-10-13" version="1" precursor="true">MVFWAALALVVGVIVAVGLARLFGRSERAVSGSHNPQALSVVGSALLSSFILLTAFLIASTWSTYNTDRQHTYDEARSVTTAYWLAGKLQPADRERVRAGLSMYTSEVVADDWPAMGRRQTSATPAATLDGLRVEVGAIQPATAADEKDRADVAAALDDIYSKRLIRAADVNYSMPSLLYIAMVIAAVLLIAYPPLVGLTANGRNVMVLAGLGAMVGLGILIVVGLSQPYSEPLSIEPTAFRHALQQFTQING</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X2</accession>
    <name>C7Q9X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796016.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7466"/>
    <dbReference type="EnsemblBacteria" id="ACU76291">
        <property type="protein sequence ID" value="ACU76291"/>
        <property type="gene ID" value="Caci_7466"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7466"/>
    <dbReference type="eggNOG" id="ENOG5032XQ6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086950_0_0_11"/>
    <dbReference type="OMA" id="GDDETRY"/>
    <dbReference type="OrthoDB" id="1120112at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982943" evidence="2">
        <location>
            <begin position="30"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="278" mass="27694" checksum="B3FCD1B440906F56" modified="2009-10-13" version="1" precursor="true">MRLTRIPAGSATTAIAAAMMVTMSGTAHAGATVPAAPAIPAAPSPHDVAAARDAANGALPTVGQFFASGGHKPQGDAHQLAAAAAAAAPRIDGATVPVYYLSPAFVADPSASGTATPVAQLSFLATDTISASGTHASVWTADVGSQGWKVVNIASGSDETTYTAQATPGAAVFEEPQIGAWYQVVGGRVLPLNAAARASVGSGVTLADYHQLVRTRYADKMPGSAYDKAGLAGGFQPTVASKNSSTNTAPLTAGVVLIGFGVVGAGAVSWRRSRAQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA06</accession>
    <name>C7QA06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, IclR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785698.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1481"/>
    <dbReference type="EnsemblBacteria" id="ACU70404">
        <property type="protein sequence ID" value="ACU70404"/>
        <property type="gene ID" value="Caci_1481"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1481"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_5_4_11"/>
    <dbReference type="OMA" id="VNRTVVY"/>
    <dbReference type="OrthoDB" id="370329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="75"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="23460" checksum="56EBE61E35D08D3D" modified="2009-10-13" version="1">MTRTDPAPEPETSQTLDRGIRVLTALADATSGLTVAQLAERVGAPRTAGYRLVATLEAHGLARRDADGRVHLGVGVLRLAARVHPLLREAATPPLRKLAEVVGATAHLTVAEGPDALAIAVVEPTWTDYHMAYRVGSRHRLAQGAAGKAILLGRAGVGRPASVSKDPATLYTASEGELQAGAHGIAAPIRDVPGLEASVGVVSFAPLDAAKVAPRVIQAAAEISAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA07</accession>
    <name>C7QA07_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70405">
        <property type="protein sequence ID" value="ACU70405"/>
        <property type="gene ID" value="Caci_1482"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1482"/>
    <dbReference type="eggNOG" id="ENOG5031BVP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118556_0_0_11"/>
    <dbReference type="OMA" id="DTGRWNT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="23380" checksum="6F1A4B03AAC8A651" modified="2009-10-13" version="1">MGTDDDLFRRQRLLQGEAEAVLDDLDLAAGLETVGDPIRTGSSALGVMVKPDIDVTTACARLDLAAFDAVAHLATRLARHARVRQVTFRNDTGVWNAEPDKYPDGLYLSVSYRSPRPRDWSLDLWFVDEPDRQPDLAHLRTLLPRLTDETREAILRIKEGWTPRPEYGREVNGTLIYEAVLDGGVRTLPDFAEWLAQDAPALKTDTARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAB0</accession>
    <name>C7QAB0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1587"/>
    <dbReference type="EnsemblBacteria" id="ACU70508">
        <property type="protein sequence ID" value="ACU70508"/>
        <property type="gene ID" value="Caci_1587"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1587"/>
    <dbReference type="eggNOG" id="ENOG5032Z6D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108006_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="22582" checksum="2BDA9314B753A158" modified="2009-10-13" version="1">MSAKKTFGSEAGCLAACDHRRVDQNDLQKAGLPSLKDAQLRHMRQLFLTVVTGGFVVLVPWIVYLALVLPDQHPENAWNAAWVGFDTLLLLGLFTTTWGAWRRRQYTVIACVFTATLLLCDAWFDISLDWGTSDETASILSAVFAEVPLALYLFYAAMRIVRMTIRSALLLAGYPGPVPQFHKLSIGGLNELLKSVDARREQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAC2</accession>
    <name>C7QAC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase C1A papain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792150.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3515"/>
    <dbReference type="MEROPS" id="C01.164"/>
    <dbReference type="EnsemblBacteria" id="ACU72421">
        <property type="protein sequence ID" value="ACU72421"/>
        <property type="gene ID" value="Caci_3515"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3515"/>
    <dbReference type="eggNOG" id="COG4870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056603_2_0_11"/>
    <dbReference type="OrthoDB" id="1064956at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981503" evidence="1">
        <location>
            <begin position="25"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Pept_C1" evidence="2">
        <location>
            <begin position="99"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="31865" checksum="2DE8258CB270015F" modified="2009-10-13" version="1" precursor="true">MHHGKTVGIAAAFATAAALTGVAAAPASASAEQSGATHHRHFATGLNIAQARAAERAGMAAQSGHSAQLVQLRGLRTADGLRADVPDSASLQQYALSPGDQGQVGSCVTWATGYSAYGILMNEQGISGDPMAPMYIYAQIAQGNDEGTNGDVALGMEQDQGIDTNSDYYQGSFDYTTQPDANERANAAHYKLSGYQTLPVGGGSEDAIKSAISQGLPVSVGFNVRQSFMDLSAQDASNYSYQPGDDSSDPVVGGHEVAVIAYTDQGVTIENSWGSSWAADGYVTVPWSFFSTGDVDELYAVGKLTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAH6</accession>
    <name>C7QAH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792204.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3570"/>
    <dbReference type="EnsemblBacteria" id="ACU72475">
        <property type="protein sequence ID" value="ACU72475"/>
        <property type="gene ID" value="Caci_3570"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3570"/>
    <dbReference type="HOGENOM" id="CLU_2166445_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="110" mass="12566" checksum="1E30D067C3581362" modified="2009-10-13" version="1">MFDLRKLIPIHRTASRSTPEDVVREAEAVVHRCWLDQLTERRREMEAALRRAADRCDAAQHSLTAAQRSGDPRMIAVSQRDLEKALEAARKTLLAWERTCRALSSEADLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB45</accession>
    <name>C7QB45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796061.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7511"/>
    <dbReference type="EnsemblBacteria" id="ACU76336">
        <property type="protein sequence ID" value="ACU76336"/>
        <property type="gene ID" value="Caci_7511"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7511"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_982427_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30086" checksum="DBB1403E3D1F61FB" modified="2009-10-13" version="1">MEDGEGHAGGFAEAIRAWRERRGWTQEELSHASGLSTRAIRSLERGRTLKPRRTTVQMLADALQVPRARLMGTVRRAVGDADAEADGTLGNVATGSVEGDAVATVSAEARSIHAGAWVPRELPPDLGHRTLDVREVVAELVAGPTEPYRAAMVRVDGSDVAIRAAHHASAKFSDGQLYARLDGTPPVAPAAVLRRFLRSLDAPQRPSDATVDELAAAFRSALAGRRMLVVLDGARSEAQILPLIPAEARCALLVAFVTEGRPVARPPSPVPSYRATPGVARPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB62</accession>
    <name>C7QB62_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796078.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7528"/>
    <dbReference type="EnsemblBacteria" id="ACU76353">
        <property type="protein sequence ID" value="ACU76353"/>
        <property type="gene ID" value="Caci_7528"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7528"/>
    <dbReference type="eggNOG" id="COG2815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087945_0_0_11"/>
    <dbReference type="OrthoDB" id="1739259at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="271" mass="29071" checksum="AB59AF3F21FAAE22" modified="2009-10-13" version="1">MHEIFVNYRTNDAHDAAFAIQADLTHRFGADKVFYASRSLKHGVPFGDALIREAGKARVLLAVIGSEWLKRDARGHRLVDDENDWVRREIVAALNAGTHVIPVLVGRTTDRLPNDLPPDIKDLLNFNYRRFDHREAEAQLPQIAAAVQEVVPGLIDNTEQKPEPPSMAGTTSTNQSGGSTIGTQGGRSVNVTGDHQGGTHLSGDTHGDVHISGDRRDGIHIDGDQSGGTNYGGAINTGGGTFIGSSRGNVHTGSGAQFNTLPTDDDPDDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBD6</accession>
    <name>C7QBD6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1592"/>
    <dbReference type="EnsemblBacteria" id="ACU70513">
        <property type="protein sequence ID" value="ACU70513"/>
        <property type="gene ID" value="Caci_1592"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1592"/>
    <dbReference type="eggNOG" id="COG1813">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2192281_0_0_11"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11450" checksum="E6C6DA4D9F9C70F2" modified="2009-10-13" version="1">MSGNYDRLAAMIVKAREARGWSQSDLANLAYVTEVVIARVEAGNPPNMVALKAVEQALGWLPGIFDLILGQDADADGDEDALAAAGDDEDDGSAELRELTVDSSIDWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBF5</accession>
    <name>C7QBF5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785826.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1611"/>
    <dbReference type="EnsemblBacteria" id="ACU70532">
        <property type="protein sequence ID" value="ACU70532"/>
        <property type="gene ID" value="Caci_1611"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1611"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_2_11"/>
    <dbReference type="OMA" id="FAEPRVY"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="411" mass="44205" checksum="688B27C20D53BA88" modified="2009-10-13" version="1">MATAPHLDQDALRRLHRTIAARVGRGELPGVVTLVARVGDGDDHGDSSGSGSEQVDVGVFGETDLTDGDPLRRDTPFRITSMTKPIVAAAVLSLVDAGILDLDAPIDPFLPELANRRVLTRLDGPLDDTVPADRAITVRDLLTFRLGFGMNGEPPDINPPSPINLAAEERDLVLAQPEPRTAHSPDAWTRLFGELPLMEQPGTRWRYNVGSLVQGVLLARAAKAPLEEVVKERILDPLGMSSTGFHVPEAEARRLPGYYVTDFATGKLTRQPADPWQTWAAPAVFPSGAAGLISTADDYYAFARMLLRRGSHEGRQILSPESVEMMTTNQLTPEQVSEAGFPLNGSGWGMGVSVTADRYGWNGGYGTSWFNDPSRGICAIFLSQTSDAIFNGTTDEFDTLASQAAATDPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH5</accession>
    <name>C7QBH5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785846.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1631"/>
    <dbReference type="EnsemblBacteria" id="ACU70552">
        <property type="protein sequence ID" value="ACU70552"/>
        <property type="gene ID" value="Caci_1631"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1631"/>
    <dbReference type="eggNOG" id="COG1396">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033540_1_1_11"/>
    <dbReference type="OMA" id="PQLVRNH"/>
    <dbReference type="OrthoDB" id="895136at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="44702" checksum="BB84DCE6464C1E00" modified="2009-10-13" version="1">MATYEQEPDGGRIRRLRRRAGLTQAEFGQLMGRSQGWVSGIENGDLELDSVTLIVRAASVLKVYPNEITGRPYDPGTRAEDRGHRAIPALRRVVSRHDLPPDWPVEPRSRRELEAAVEQLAVLRMAARYADLGEAAPNLIREIHAAAYVARSGEESERLHGLLARAYKEADTVAHELGYDDLSTLTTERFRAAAQRAGDPCLSVVFDYLRVRDLWAADLWPDALDLIDGAIGFVGEPRQKEQASVWGSLQLRAAITAALSSKEDEAWQRIALADETARRLGEGYDPYKLAFCSANVDIHKLAVAVEIRDGARAVALASQTRLPASFPASRRGRFHLDAARGWIYHGGYDQALNEIERAERIAPLLVRNNPVAKAAVRSLLSHERRSQRERLRRMAGRMHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBZ0</accession>
    <name>C7QBZ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate binding family 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792338.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3707"/>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH87">
        <property type="family name" value="Glycoside Hydrolase Family 87"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72609">
        <property type="protein sequence ID" value="ACU72609"/>
        <property type="gene ID" value="Caci_3707"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3707"/>
    <dbReference type="eggNOG" id="COG5434">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008465_0_0_11"/>
    <dbReference type="OMA" id="NTIAYRF"/>
    <dbReference type="OrthoDB" id="32528at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14490">
        <property type="entry name" value="CBM6-CBM35-CBM36_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033801">
        <property type="entry name" value="CBM6-CBM35-CBM36-like_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16990">
        <property type="entry name" value="CBM_35"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981534" evidence="2">
        <location>
            <begin position="50"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="3">
        <location>
            <begin position="52"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="3">
        <location>
            <begin position="188"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="3">
        <location>
            <begin position="339"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1000" mass="101805" checksum="EA3A90260B668BE3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC86</accession>
    <name>C7QC86_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5676"/>
    <dbReference type="EnsemblBacteria" id="ACU74534">
        <property type="protein sequence ID" value="ACU74534"/>
        <property type="gene ID" value="Caci_5676"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5676"/>
    <dbReference type="eggNOG" id="COG2244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_482902_0_0_11"/>
    <dbReference type="OMA" id="RTITSWR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="564" mass="54317" checksum="5E74E5ED5C4299E7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH0</accession>
    <name>C7QCH0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcriptional regulator WhiB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">whiB</name>
        <name evidence="13" type="ordered locus">Caci_7609</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">The Fe-S cluster can be nitrosylated by nitric oxide (NO).</text>
    </comment>
    <comment type="PTM">
        <text evidence="11">Upon Fe-S cluster removal intramolecular disulfide bonds are formed.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the WhiB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7609"/>
    <dbReference type="EnsemblBacteria" id="ACU76433">
        <property type="protein sequence ID" value="ACU76433"/>
        <property type="gene ID" value="Caci_7609"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7609"/>
    <dbReference type="eggNOG" id="ENOG5032RUK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106245_4_3_11"/>
    <dbReference type="OMA" id="KRICGRC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035731">
        <property type="term" value="F:dinitrosyl-iron complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01479">
        <property type="entry name" value="WhiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034768">
        <property type="entry name" value="4FE4S_WBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003482">
        <property type="entry name" value="Whib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38839">
        <property type="entry name" value="PTHR38839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02467">
        <property type="entry name" value="Whib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51674">
        <property type="entry name" value="4FE4S_WBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="4Fe-4S Wbl-type" evidence="12">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU76433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="11565" checksum="7E6967F8FFAC5732" modified="2009-10-13" version="1">MAEAAENTEGAEEACHAEVYRIYPLHNGVDEDRGWQARALCAQTDPESFFPEKGGSTREAKKICLNCEVKAECLSYALSNDERFGIWGGLSERERRRLKRAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCK6</accession>
    <name>C7QCK6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796194.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7645"/>
    <dbReference type="EnsemblBacteria" id="ACU76469">
        <property type="protein sequence ID" value="ACU76469"/>
        <property type="gene ID" value="Caci_7645"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7645"/>
    <dbReference type="eggNOG" id="COG4636">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076312_4_0_11"/>
    <dbReference type="OrthoDB" id="2040599at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="30"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="21988" checksum="F5E3A164F8A0C2D3" modified="2009-10-13" version="1">MSSPDDGKRTEEGFDLNSIMHASEPLTTKEFFALDVDEKLKVELIGGALAVSPSSMFWHNRVANRLFRIFEDSLGSGFPVFTDLDVTLDTTTVVRPDVFVISAAGYAPNRTALASDVVLAIEIMSPGSRVNDRHVKPWLYHDAGIPSCRIERSGRHLALFEVVHRDEEQVRLGQFTLKVADIDVPIDLDSIARYTLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ7</accession>
    <name>C7QCZ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aconitate hydratase</fullName>
            <shortName evidence="10">Aconitase</shortName>
            <ecNumber evidence="10">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">Caci_1786</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="10"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1786"/>
    <dbReference type="EnsemblBacteria" id="ACU70707">
        <property type="protein sequence ID" value="ACU70707"/>
        <property type="gene ID" value="Caci_1786"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1786"/>
    <dbReference type="eggNOG" id="COG1048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013476_2_1_11"/>
    <dbReference type="OMA" id="NGGIMQY"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047456">
        <property type="term" value="F:2-methylisocitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="11">
        <location>
            <begin position="67"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="12">
        <location>
            <begin position="684"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU70707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="882" mass="95049" checksum="115A640E1496CBE8" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE00</accession>
    <name>C7QE00_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl-CoA hydratase 2</fullName>
            <ecNumber evidence="1">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Enoyl-CoA hydratase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7764</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.1.119" evidence="1"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796313.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7764"/>
    <dbReference type="EnsemblBacteria" id="ACU76588">
        <property type="protein sequence ID" value="ACU76588"/>
        <property type="gene ID" value="Caci_7764"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7764"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_0_1_11"/>
    <dbReference type="OMA" id="RKVMVPT"/>
    <dbReference type="OrthoDB" id="1563802at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="5">
        <location>
            <begin position="12"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18852" checksum="3F9427EB475B85EE" modified="2009-10-13" version="1">MQFGRYFEEFEVGAVYKHWPGKTVTEYDDHLFCLITMNHHPLHLDANYAEETTDFKRNVVVGNYIYSLLLGMSVADVSGKAIANLEVESLRHIAPTFHGDTIYGETEVLDKTESKSKDDRGIVYVQTKGYKQDGTVVCVFRRKVMVPKRSYGDARGGEQPGRPTPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE69</accession>
    <name>C7QE69_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796382.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7833"/>
    <dbReference type="MEROPS" id="G01.006"/>
    <dbReference type="EnsemblBacteria" id="ACU76657">
        <property type="protein sequence ID" value="ACU76657"/>
        <property type="gene ID" value="Caci_7833"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7833"/>
    <dbReference type="eggNOG" id="ENOG502ZVX8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076823_1_0_11"/>
    <dbReference type="OrthoDB" id="1546331at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PTHR37536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980888" evidence="1">
        <location>
            <begin position="30"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="24571" checksum="9EF8E1486418039F" modified="2009-10-13" version="1" precursor="true">MSSSRRRTAAAVALAGAMTAALAATPASAGVVHRTPSAFRHDIRNSTSGNWAGYVATGGGFTSVSAGWTEPAVSCRSQNTYASFWIGLDGDGSNSVEQIGTESDCSGGHAVYSAWYEMYPGAPVDVAGPISPGDAMQASVSYGGSGHFTLVLADRTKGWTRTVQAQLNNPALASAEVIAEAPSDAAGVLPLSDFGTVGFTGASANGAALGSFAPDPITMANGGTTKAVPSGLSPSGDFTVAWRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEK4</accession>
    <name>C7QEK4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786188.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1975"/>
    <dbReference type="EnsemblBacteria" id="ACU70895">
        <property type="protein sequence ID" value="ACU70895"/>
        <property type="gene ID" value="Caci_1975"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1975"/>
    <dbReference type="eggNOG" id="COG0384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048756_0_1_11"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="294" mass="32306" checksum="B1AE3151B33EED5A" modified="2009-10-13" version="1">MQYFHVDVFSSQPYSGNSLAVFPDATALTGSQMAQITRELRHFESIFLLPEGEGADVHRRQARVFDLIEELDFAGHPVLGAACVLHELRGSETPETLPETWSITLPARTVQITTQRRSQGHFSAVLDQGQAEFRETTAPHDVASWFSLDDKDLDPELPPQVVSTGLRYLILPVRPGTLERARIAIPDLDIRLEALGAQFAYLLDAEAMEGRHWNNDGVLEDVATGSAAGCVAAYLRRHDRLGDGETATLHQGRFLDRPSTITLRAHGSGTDISSVEVEADVVFVARGTLDRIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEZ2</accession>
    <name>C7QEZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794479.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5892"/>
    <dbReference type="EnsemblBacteria" id="ACU74750">
        <property type="protein sequence ID" value="ACU74750"/>
        <property type="gene ID" value="Caci_5892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5892"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="FYRGQHT"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="310" mass="31713" checksum="0EB4FCF4296B3F2F" modified="2009-10-13" version="1">MRAVGVKDYGATPELLDVPKPAAGPGQLLVRVEAAGINPVDAIIASGASGSSGRPPLPLVMGVDFAGRVEAVGQGVTRYAVGDPVFGRAAGTYAEYVVVDETGPLSPAPDAVELKTAAALPTAGLTALGVLDAAGVRGGESLLLIGAAGGVGTFLTQLASARDARVVAVTRGDESVRLGLFGAAVTIDATAEDVAGRVRREEYPEGVDVLVDLVSQDAEAFEANKELVHDGGVAVSTRGATREHGKVQSGVEELAFRMQPSAELLAELVKEVDEGTLRVFVEEEVPLEQAPQAVARIQHGGARGKTIVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF07</accession>
    <name>C7QF07_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">1-phosphofructokinase</fullName>
            <ecNumber evidence="7">2.7.1.144</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.144" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794494.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5907"/>
    <dbReference type="EnsemblBacteria" id="ACU74765">
        <property type="protein sequence ID" value="ACU74765"/>
        <property type="gene ID" value="Caci_5907"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5907"/>
    <dbReference type="eggNOG" id="COG1105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050013_0_2_11"/>
    <dbReference type="OMA" id="QLNEPGP"/>
    <dbReference type="OrthoDB" id="1323781at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009024">
        <property type="term" value="F:tagatose-6-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="6">
        <location>
            <begin position="21"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="31187" checksum="B04032299F99DA8E" modified="2009-10-13" version="1">MIVTLTLNPALDITYSVAELKAGTTHRPRVYAQAGGKGVNVSRTLHALGRETVAVLPLGGFDGEAVRAELEASGVPHHAIPIAGATRRTVTVVEGSGLATGFNESGPEVSADEWAEICAAVGSLLETAVLDGAPVLVLSGKLPRGVADDAYAELIALADGFGVPTILDTEGAPLLAALAAHPAIVKPNAHELLDATGMSDSRAAAAELLERGARAVVSSNGPDGLTALTSEGSWSARPPRIEGGNPTGAGDASVAALAVGLVDGSPWLELLADAAALSAATVLTDRAGVFDAEAYERFRFAISAHPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF92</accession>
    <name>C7QF92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine-specific ribonuclease N1 and T1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5992</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794579.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5992"/>
    <dbReference type="EnsemblBacteria" id="ACU74850">
        <property type="protein sequence ID" value="ACU74850"/>
        <property type="gene ID" value="Caci_5992"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5992"/>
    <dbReference type="eggNOG" id="COG4290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112496_2_0_11"/>
    <dbReference type="OMA" id="CYYTDDY"/>
    <dbReference type="OrthoDB" id="1964970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982808" evidence="4">
        <location>
            <begin position="40"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="144" mass="15470" checksum="73BAD4E0A1398628" modified="2009-10-13" version="1" precursor="true">MSPSAPPRRVQPLVVLLLAILLALAGCGASSGKSSSSSASSSSLLKPAGMATVAEASLPAEARDVIKRIDDGGTFQYRQDGVTFQNRERRLPSEPSGYYREYTVVTPGAADRGARRLILGHNGELYYTPDHYRSFLWVVRGGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFD9</accession>
    <name>C7QFD9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796441.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7893"/>
    <dbReference type="EnsemblBacteria" id="ACU76716">
        <property type="protein sequence ID" value="ACU76716"/>
        <property type="gene ID" value="Caci_7893"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7893"/>
    <dbReference type="eggNOG" id="ENOG502Z7KB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_701917_0_0_11"/>
    <dbReference type="OMA" id="HLAMEGF"/>
    <dbReference type="OrthoDB" id="471493at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="377" mass="42195" checksum="CB54A68901590BE7" modified="2009-10-13" version="1">MRIDLTGLRTGPAQTWGAIRLVPLLRDQPVEGLRLHRIAYAEEPRWSEVKLGSKTSYYSYIPHGFVADWNRDGGDSGQSAAFGTQILDQRGGVRGMPMQVHRRMTQKMGKQRVRFLPLHFALEGYLALHFGGPDIAWREWSDRVLRHGLSPREEAAYRGTTVTGLQDALKVFEIHAGQCGVLLYTADALAAAFVVPHPEDYRELHPTLVLDHFGELIYQYALMMPAVQEFRASIADQGIDSLAELRAAAEAQFAQWAEFHDRVVANALLDRDYTAERGYRMGAFDLVRFRPAFKPGEENHIGEAITDGDGAIAYLKTFRLSEAQIRRGYLLELLAAHDWRLSAAATVIGTTAANLRTRIEAAGFGMMLRQKEKTAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFJ1</accession>
    <name>C7QFJ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7945"/>
    <dbReference type="EnsemblBacteria" id="ACU76768">
        <property type="protein sequence ID" value="ACU76768"/>
        <property type="gene ID" value="Caci_7945"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7945"/>
    <dbReference type="eggNOG" id="COG3599">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1458815_0_0_11"/>
    <dbReference type="OMA" id="GYRMTEV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019933">
        <property type="entry name" value="DivIVA_domain"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03544">
        <property type="entry name" value="DivI1A_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="19213" checksum="D5B33246B8A4B09A" modified="2009-10-13" version="1">MAVLYFQFLVVAAVFGAIAWVAAGRGGGLDDPRQDRPEPALADDRQLGREDIDSARFAVGWRGYRMDQVDRLLDRLAAEIDHRDRLIADLTRPAGARLGEAGVGYEPVARTQDGTPGGEGLGGGGDAGGAATATAVVQPGFGPGVGGVGGVGDVVPGRVEPAIPADQNPADNPLSAWYRRPEDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG84</accession>
    <name>C7QG84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792658.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4064"/>
    <dbReference type="EnsemblBacteria" id="ACU72929">
        <property type="protein sequence ID" value="ACU72929"/>
        <property type="gene ID" value="Caci_4064"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4064"/>
    <dbReference type="HOGENOM" id="CLU_1419179_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="191" mass="20173" checksum="374523183E7F2F23" modified="2009-10-13" version="1">MHPEHPADPLGRALAEYGWTISSTDHPAQVFDPEARIWNSPDTQLMLSAHGERDGRHMITLYAPRAPQETEDPLWQVGGGPVPVATALAMARAALTAPAEQDHAAALTATGWTLAPEHVLSVSIAGLESWIGPAVDDEPTGFWAAFRFPMPTDELSTWTVKGAHGGTECSLIATAATPGEVIAAAAHHAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGK1</accession>
    <name>C7QGK1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794610.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6024"/>
    <dbReference type="EnsemblBacteria" id="ACU74881">
        <property type="protein sequence ID" value="ACU74881"/>
        <property type="gene ID" value="Caci_6024"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6024"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_11"/>
    <dbReference type="OMA" id="YPVPDDM"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="31749" checksum="87D123270859870C" modified="2009-10-13" version="1">MIDVRQLRTLRALADHGTVSAAAEALYLTPSAVSQQLAVLSKSTGCELLERRGRNVVLTEAARVLVGHADAVFAQLERAQSELRAISPAPMTVRIAGFPTAVMAVIAPAMKALREAHEEWRFEIADTESEESVAHLIDGTVDVAVVMAAPNRPLLGDPRIRILPLLEEVYVAAVPAGHRLAAAERIGLADLVEEPFVLAAEGLSCHDQVTAICADAGFQPRGRYRATDFSAALALIANGFGVTLLPTLGVPPLMPEGVVLVPLKEDWPRRVSLIAVRTGAEYPEVVTALAEAAAKLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL4</accession>
    <name>C7QGL4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydrogenobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Hydrogenobyrinic acid a,c-diamide synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="6" type="ordered locus">Caci_6037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine = 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:12544"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:77873"/>
            <dbReference type="ChEBI" id="CHEBI:77874"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 9/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.9" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6037"/>
    <dbReference type="EnsemblBacteria" id="ACU74894">
        <property type="protein sequence ID" value="ACU74894"/>
        <property type="gene ID" value="Caci_6037"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6037"/>
    <dbReference type="eggNOG" id="COG1797">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022752_1_1_11"/>
    <dbReference type="OMA" id="QPFKCGP"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043802">
        <property type="term" value="F:hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="258"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="456" mass="47379" checksum="379E481B745A24EE" modified="2009-10-13" version="1">MRSAPLSVPRIVIAAPASGHGKTTVATGIIKALTDRGFTVAPFKVGPDYIDPGYHSLAAGRTGRNLDPYMVGTERIAPLFAHGAAGADLAVVEGVMGLYDGATGEGELASTAQVAKLLDAPVLFVVDAAAQGRSIAALLHGFRSFDPAVRIAGVVLNRVGSDNHRNILTQALDEIGLPVLGALRRDAAVSAPSRHLGLVPVAERRAEALASVAALGALVDTGLQLDEVYRLARSAPPLDVTAWDPFEEVGSRRGARPRIAVASGPAFTFSYAENTELLAAAGAEVCPFDPLREEKLPERVCGLVLGGGFPEVYAPELAANEALRENVAEFARLGGAIAAECAGLLYLGKSLDGLPMCGVVDAEAVMTDRLTLGYRHAVAASESVLAAAGTRVSGHEFHRTAVSPSAGSPPAWHWRRNGGAVTEGFAGARIHASYLHLHWAGAPSIARRLVESCGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGM5</accession>
    <name>C7QGM5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794634.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6048"/>
    <dbReference type="EnsemblBacteria" id="ACU74905">
        <property type="protein sequence ID" value="ACU74905"/>
        <property type="gene ID" value="Caci_6048"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6048"/>
    <dbReference type="eggNOG" id="COG3200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026885_0_1_11"/>
    <dbReference type="OMA" id="WNQDFVK"/>
    <dbReference type="OrthoDB" id="1371606at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PTHR21337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01358">
        <property type="entry name" value="DAHP_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="454" mass="49625" checksum="5BBFD519030AE857" modified="2009-10-13" version="1">MSEVVRNPAGTGSIEDTWSALPAGQQPEWPDAAELSSVVSELRSYPPLVFAGEADQLKDRIAAVSRGEAFLLTGGDCAETFAGVTADAIRAKLKTLLQMAVVLTYAASLPVVKVGRIAGQYSKPRSKPTETRDGVTLPAYRGDSVNGFDFTPEARTPDPKRLLRLYQASASTLNLVRAFTTGGYADMRQVHAWNQDFVAGSPSGERYEALAGEIDRALQFMRACGTEPEELRTVEFYAAHEGLVLPYESALTRIDSRTGNPYATSGHYIWIGERTRDLDGAHVEYFSRISNPIGIKLGPGTAPDDALSYLDRLDPDREPGRLSFIVRMGAGQVREKLPALVEKVRGEGHQVAWICDPMHGNTFEAPSGHKTRRFDDVLDEVKGFFEVHHGLGSHPGGIHVELTGEDVTECVGGGTEIALDALHQRYETLCDPRLNRSQSLDLAFLVAEMLRARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHC1</accession>
    <name>C7QHC1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784355.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0105"/>
    <dbReference type="EnsemblBacteria" id="ACU69060">
        <property type="protein sequence ID" value="ACU69060"/>
        <property type="gene ID" value="Caci_0105"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0105"/>
    <dbReference type="HOGENOM" id="CLU_1465715_0_0_11"/>
    <dbReference type="OrthoDB" id="2219881at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="184" mass="19318" checksum="8C648F01AD750109" modified="2009-10-13" version="1">MNAMTVPPMSSPAMPQNQEQEGPGEAVDIPQQQDAEPRQEEMPAVTAAETEPGGGAGETGEPAADGDEGKEPAADAGETSGDRDEKEEKEDKDEKKTAAKPKRKSAPRKTAGGSKTLVVLKGGRVQYADTDAVVVVDLDEAASPDTDVHDVLDRLTELRDATESPAKTDAVRALTDLIQEKALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHF6</accession>
    <name>C7QHF6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784390.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0140"/>
    <dbReference type="EnsemblBacteria" id="ACU69095">
        <property type="protein sequence ID" value="ACU69095"/>
        <property type="gene ID" value="Caci_0140"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0140"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060076_0_0_11"/>
    <dbReference type="OMA" id="IAMNGVT"/>
    <dbReference type="OrthoDB" id="1339160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="50"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="152"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="42951" checksum="E739F3CB5DBB9A00" modified="2009-10-13" version="1">MTRETVGIAMNGVTGRMGYRQHLLRSILAIRDQGGLALPDGRTVWPEPILVGRNAEKIEALATRHGLDKWTTSLDEALADPSVTVYFDAQVTQARVPAITRAIEAGKHIYTEKPTAETLDDAISLARIADAAGIKHGVVQDKLFLPGLLKLKRLVDSSFFGRILSVRGEFGYWVFEGDWQPAQRPSWNYRAEDGGGIILDMFPHWRYVLDHIIAPVRSVYAEARTDIPTRWDEQGREYKATADDAAYALFELEGGIVASLNSSWTTRVNREELVEFQIDGTHGSAVAGLRNCKAQHRAATPKPVWNPDIPATEDFLAQWQEVPDNAVMDNGFKVQWEMFLAHLVADAPYSHDLWAGARGVQLAELGAQSWREGRKVAVPELDRTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN5</accession>
    <name>C7QHN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786353.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2141"/>
    <dbReference type="EnsemblBacteria" id="ACU71060">
        <property type="protein sequence ID" value="ACU71060"/>
        <property type="gene ID" value="Caci_2141"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2141"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_1_1_11"/>
    <dbReference type="OMA" id="GVHGFRN"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="62"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="17340" checksum="96E99B961B544A90" modified="2009-10-13" version="1">MSYPDPRYFADTGEVSATFRPAGAEPEITFASGGTCSLLSTSDTSGGLYGLYRWDFAAAPSGPGTHFHKTMSEAFFVLKGAVRLFNGEKWVEATPGDYLFVPPGGLHAFRNESGEPASMLLMFAPGAPRENYFRGLVEGMQNTMGEAFFLEHDQYNVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI50</accession>
    <name>C7QI50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792824.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4231"/>
    <dbReference type="ESTHER" id="catad-c7qi50">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73095">
        <property type="protein sequence ID" value="ACU73095"/>
        <property type="gene ID" value="Caci_4231"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4231"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_16_1_11"/>
    <dbReference type="OMA" id="DHVAITI"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983156" evidence="2">
        <location>
            <begin position="31"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="93"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="364" mass="38994" checksum="CBF8EC97DD668F9B" modified="2009-10-13" version="1" precursor="true">MINRRTFTKAVGLGVGATAVTAVSTGTASAALASASSGSSGSKGPGGTGGKAPVIPTIAPGTHTTFSDLKQVRAGVLDIGYAETGPKHGPVAILLHGWPYDIHSFVDVAPLLADAGYRVIVPYLRGHGSTTFLSPATARNAQQSAIALDIIAMMDSLHIRKAVVAGFDWGSRTADIMAALWPERVKALVSTSGYLITNVAAQKNPLPPKAEQIWWYQYYFATDRGQTAMQTPADRNALCRLVWDDVSPTWAFDDATFNRTAAAFDNPDYAAIVIHNYRWRLGLADGERRYDRYEQLLAAKPTIAVPTITIDPALDPFIASTDGTGYRNFFTGPYDHRVFTAIGHDAPQEAPTAFAQAVVDADHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIB1</accession>
    <name>C7QIB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794717.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6134"/>
    <dbReference type="CAZy" id="CBM5">
        <property type="family name" value="Carbohydrate-Binding Module Family 5"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74988">
        <property type="protein sequence ID" value="ACU74988"/>
        <property type="gene ID" value="Caci_6134"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6134"/>
    <dbReference type="eggNOG" id="COG3325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3979">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_14_3_11"/>
    <dbReference type="OMA" id="PAGQDKI"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM_fam5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="SSF51055"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="SSF54556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982908" evidence="5">
        <location>
            <begin position="51"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="64"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="507"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="542"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="675" mass="69875" checksum="574F5732D1460F79" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIF4</accession>
    <name>C7QIF4_CATAD</name>
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        <submittedName>
            <fullName evidence="6">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794760.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6177"/>
    <dbReference type="EnsemblBacteria" id="ACU75031">
        <property type="protein sequence ID" value="ACU75031"/>
        <property type="gene ID" value="Caci_6177"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6177"/>
    <dbReference type="eggNOG" id="COG3383">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_11"/>
    <dbReference type="OMA" id="GMNAHQH"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU75031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="699" mass="73547" checksum="C63DA99533553166" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIG0</accession>
    <name>C7QIG0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoadipyl-CoA thiolase</fullName>
            <ecNumber evidence="4">2.3.1.174</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:19481"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57348"/>
            <dbReference type="EC" id="2.3.1.174"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.174" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794766.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6183"/>
    <dbReference type="EnsemblBacteria" id="ACU75037">
        <property type="protein sequence ID" value="ACU75037"/>
        <property type="gene ID" value="Caci_6183"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6183"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_0_0_11"/>
    <dbReference type="OMA" id="NASPMND"/>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033812">
        <property type="term" value="F:3-oxoadipyl-CoA thiolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012793">
        <property type="entry name" value="PcaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02430">
        <property type="entry name" value="pcaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="9">
        <location>
            <begin position="276"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="401" mass="41828" checksum="94C731C1F32A0406" modified="2009-10-13" version="1">MTDAYLVTGTRTPFGRYGGALAPVRPDDMAAHVIRELMAGVPQIPGAAVEEVFLGDANQAGEDNRDVARMALLLAGLPVTVPGATVNRLCGSGLEALVQAARQIRLGEADVVVAGGVESMSRAPFVMGKADTAFARSADVFDTTIGWRFVNTLMKKQYGIDSMPETAENVAADFHVGREDQDAFALRSQERALRAQENGRLAKEITPISISRRKADPVLVDKDEHPRSTSMEALAKLGTPFREGGTVTAGNASGVNDGAVALLVASGEAVERYGLTPLAKVVTSHTAGVEPRVMGIGPVPATRGLLERAKLGIGDIDVVELNEAFAAQSLACLRELGLPDDAAHVNPNGGAIALGHPLGASGARLALTAALELKERQARYAVATMCIGVGQGIAVLLERAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII7</accession>
    <name>C7QII7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S45 penicillin amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6210"/>
    <dbReference type="MEROPS" id="S45.003"/>
    <dbReference type="EnsemblBacteria" id="ACU75064">
        <property type="protein sequence ID" value="ACU75064"/>
        <property type="gene ID" value="Caci_6210"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6210"/>
    <dbReference type="eggNOG" id="COG2366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011790_0_1_11"/>
    <dbReference type="OMA" id="EMDVRRH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="858" mass="93002" checksum="F17355576291BFF7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIQ6</accession>
    <name>C7QIQ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796681.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8133"/>
    <dbReference type="EnsemblBacteria" id="ACU76956">
        <property type="protein sequence ID" value="ACU76956"/>
        <property type="gene ID" value="Caci_8133"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8133"/>
    <dbReference type="eggNOG" id="ENOG5032TTR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101753_0_0_11"/>
    <dbReference type="OMA" id="IHVESPV"/>
    <dbReference type="OrthoDB" id="1808966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981677" evidence="2">
        <location>
            <begin position="38"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="213" mass="21691" checksum="119612E6E8463785" modified="2009-10-13" version="1" precursor="true">MSIPKRAALGLAAAATALIMTACSSNGSSGSANGSPAAPSTTAATAATSTGGAPSSAGGWARNPDQTSTALKAGLPMLGSEMLQVHYHAHLDVIVDGQPVTVPQYVGIDENAQTITALHTHDTSGVVHIESGKDVPFKLGQFFTEWGQPMSATQVGPVALGTDKALHVIVNGKEVAGDPAQYVLKAHDEIVVWVGAKDQTPQVPASYNFPAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS6</accession>
    <name>C7QIS6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796701.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8153"/>
    <dbReference type="EnsemblBacteria" id="ACU76976">
        <property type="protein sequence ID" value="ACU76976"/>
        <property type="gene ID" value="Caci_8153"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8153"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_0_0_11"/>
    <dbReference type="OMA" id="YELTTIM"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="327" mass="34685" checksum="CD5DF96DDAB209B3" modified="2009-10-13" version="1">MASTEGGSTERPAPIGPVDSSKTPRYAGFATFARLPRLDQLPAGEKADVAVLGAPFDSGVSYRPGARFAPAAVREASRLLRPYNPGLDFSPFEAVQVADAGDISINPFLLDEALEQIEAHSGELVGAGSKLVTIGGDHTIALPLLRTMARRHGPVALLHFDAHLDTWDTYFGAPYTHGTPFRRAFEEGILDSSAVAHVGTRGPLYSKQDLSDDQRMGFGIVTSADVMRQGVDAVVQALRERIGSRPLYVSIDIDVLDPAHAPGTGTPEAGGMTSRELLEILRGLDGLNLVGADVVEVAPPYDHAEITSVAAAHVAYDLVTLLAMQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIS7</accession>
    <name>C7QIS7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8154</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796702.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8154"/>
    <dbReference type="EnsemblBacteria" id="ACU76977">
        <property type="protein sequence ID" value="ACU76977"/>
        <property type="gene ID" value="Caci_8154"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8154"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_14_3_11"/>
    <dbReference type="OMA" id="YRDPWYG"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983176" evidence="2">
        <location>
            <begin position="46"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="3">
        <location>
            <begin position="79"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="4">
        <location>
            <begin position="452"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="550" mass="57236" checksum="107E9CA6326972D8" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIY4</accession>
    <name>C7QIY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8211"/>
    <dbReference type="EnsemblBacteria" id="ACU77034">
        <property type="protein sequence ID" value="ACU77034"/>
        <property type="gene ID" value="Caci_8211"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8211"/>
    <dbReference type="HOGENOM" id="CLU_1164212_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983252" evidence="2">
        <location>
            <begin position="34"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="24354" checksum="1809F64E5486B2F2" modified="2009-10-13" version="1" precursor="true">MELMERGKVYKGLIGAFGACLLLAGCSSSQKPAALGPVGESATDSAAGSATVSATPTGTAASSSSSTGSASGSSPAAAAPRTVITSSAGLTYKATVPGDPDSAAALTAFENYRVILTAMSSKPDYSTNLGDYADGNPLTLADTYILTLKQNNEVMVGTTTETVTSSTLTMAASPLPLMTITVCKDATKYHEVFSYGKNKGKLAVSDITHPYPLTYTVHKSADGKWRVTSVHGESDKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIZ5</accession>
    <name>C7QIZ5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gpmA</name>
        <name evidence="6" type="ordered locus">Caci_8222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796770.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8222"/>
    <dbReference type="EnsemblBacteria" id="ACU77045">
        <property type="protein sequence ID" value="ACU77045"/>
        <property type="gene ID" value="Caci_8222"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8222"/>
    <dbReference type="eggNOG" id="COG0588">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_1_1_11"/>
    <dbReference type="OMA" id="RMLPYWY"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="24"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="28179" checksum="A94E428AB8128BBC" modified="2009-10-13" version="1">MTAEYRLILLRHGESEWNAKNLFTGWVDVNLNAKGEAEAVRGGELLREQDLLPDVVHTSVLRRAIRTANLSLEAADRHWIPVRRSWRLNERHYGALQGKDKAATLAEFGEEQFMLWRRSYDVPPPPLAKDDQYSQFEDPRYAGLPTELRPQTECLKDVVDRMLPYWYDAIVPDLRTGNTVLVAAHGNSLRALVKHLDGISDADIAALNIPTGIPLLYTLDADLRPTKTGGEYLDPEAAAASIEAVKNQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ35</accession>
    <name>C7QJ35_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0224"/>
    <dbReference type="EnsemblBacteria" id="ACU69177">
        <property type="protein sequence ID" value="ACU69177"/>
        <property type="gene ID" value="Caci_0224"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0224"/>
    <dbReference type="eggNOG" id="ENOG50335TC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085581_0_0_11"/>
    <dbReference type="OMA" id="RSESPRW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="31371" checksum="B63698F3477B8F16" modified="2009-10-13" version="1">MTGHRRSPAHDATQRDQLHTHSGHLARIGRDIRDGRGLEGYAVFVTGLTMTVLGLTDAVSAPIMGAAQLLAISFLVFHSITPNRHRAVDVLAGREAFAPFPSLLPHARDLRIYGPTAINVVVHLAEIRRLVLARGGMVRIVVQKPDPIQLRHTAVQLDQGLDLDQTLTAAIRSLERCDGLPGFGYRLLPFNPGFSLVVVNAGDKDGYVIVEPHGFGDQAISDRMHLRITRSESPRWFAYWVDRFDAIWAASSDGEHASSGAKPGTDGETRSEGRLGSLSQPDAEQGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJA0</accession>
    <name>C7QJA0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <shortName evidence="5">FGAM synthase</shortName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Formylglycinamide ribonucleotide amidotransferase subunit III</fullName>
            <shortName evidence="5">FGAR amidotransferase III</shortName>
            <shortName evidence="5">FGAR-AT III</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purS</name>
        <name evidence="6" type="ordered locus">Caci_0289</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PurS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0289"/>
    <dbReference type="EnsemblBacteria" id="ACU69242">
        <property type="protein sequence ID" value="ACU69242"/>
        <property type="gene ID" value="Caci_0289"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0289"/>
    <dbReference type="eggNOG" id="COG1828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164833_1_0_11"/>
    <dbReference type="OMA" id="IENYRFE"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01926">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="88" mass="9653" checksum="71B4FD8976AF7203" modified="2009-10-13" version="1">MARVLVDVMLKPEILDPQGQAVQRALPRMGFDSVTNVRQGKRFELELADADPATLRATAEQMAEKLLANTVIEDFKVTVLPADSSENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJU1</accession>
    <name>C7QJU1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792908.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4315"/>
    <dbReference type="EnsemblBacteria" id="ACU73179">
        <property type="protein sequence ID" value="ACU73179"/>
        <property type="gene ID" value="Caci_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4315"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133220_0_0_11"/>
    <dbReference type="OMA" id="ACVHWTG"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="18911" checksum="A9791DFDC336A494" modified="2009-10-13" version="1">MSPSAARVKSPRDLRTERRRRSHSCWDHLIAAPLWPMHEANLGTLLRTCDAVGACLAVPRLPWVPEALARGNTLRHPACIHWTGDQLSWLTHQHTRTDTTIVGAELADEALRLADLPPARNRTVLVLGHERDGIPPDAVALLDLAVEIPMVGTGASLNVAVAGSLVLYRLAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK24</accession>
    <name>C7QK24_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4398"/>
    <dbReference type="EnsemblBacteria" id="ACU73262">
        <property type="protein sequence ID" value="ACU73262"/>
        <property type="gene ID" value="Caci_4398"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4398"/>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_382520_0_0_11"/>
    <dbReference type="OrthoDB" id="1446021at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="573"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4157" evidence="3">
        <location>
            <begin position="90"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="723" mass="74027" checksum="85C298CB78CFAF08" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKL1</accession>
    <name>C7QKL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8287</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796835.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8287"/>
    <dbReference type="EnsemblBacteria" id="ACU77110">
        <property type="protein sequence ID" value="ACU77110"/>
        <property type="gene ID" value="Caci_8287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8287"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_11"/>
    <dbReference type="OMA" id="FDTGWRG"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="161"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="386" mass="40078" checksum="56BBE3D75692AC05" modified="2009-10-13" version="1">MRDQLEIIAMGAGSAVGASLIGWSALRALRGRSLRASLFASAATAALAVVAGIVIASRAMFISSHDAGVSVIVSSSGAAVTLALAWLLGRSLAHDSRTLRAALQALGEGESVPGPAPHGRALMTGELAALDRELRATQAKLAESRERERALERSRRELVAWVSHDLRTPLAGLRAMAEALEDGVASDPARYHMQMRLAADRLAGMVDDLFELSRIHAGALRLTLESVALADLVDGALAEGQPLARARGIELSGVVTTPATVRGDVRELSRALSNLVVNAIRHTPEDGTVRIEASALARTGADGEPRVLLAVTDACGGIPDEDLDRVFDVAWRGTAARTPEVESPVGAGAGLGLAIVRGIAEAHSGAVTVGNVDGGCRFEMHLPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVH7</accession>
    <name>C7PVH7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_0380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784628.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0380"/>
    <dbReference type="EnsemblBacteria" id="ACU69333">
        <property type="protein sequence ID" value="ACU69333"/>
        <property type="gene ID" value="Caci_0380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0380"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_9_0_11"/>
    <dbReference type="OMA" id="ALAFWTR"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="23395" checksum="D0AB7763C80FFF6F" modified="2009-10-13" version="1">MVQTETGTPRQRYRAQVQEEIKQHAWEQIATAGASALSLNAIAKQMGMSGPALYRYFANRDELITALIRDAYQSMADAMRAAVADGAGLRGLARTLREWALEDPQRYLLIYGTPVPGYQAPEDTTRLANDVMALLLDASSAEGLGALPPSPVQTHLEQHSPWAGAHAGEGTTLHRAVILWTRLHGVLSLELAGHFAGMEFDPALLYAAEVEAVAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVU8</accession>
    <name>C7PVU8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2422</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2422"/>
    <dbReference type="EnsemblBacteria" id="ACU71340">
        <property type="protein sequence ID" value="ACU71340"/>
        <property type="gene ID" value="Caci_2422"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2422"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_4_11"/>
    <dbReference type="OMA" id="IDQDLCT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="102" mass="10754" checksum="48F7FA0189C5268D" modified="2009-10-13" version="1">MIMTVTTDTDALEVWIDHDLCTGDGICAQYAPDVFELDIDGVAYVKNGPDAELLTGAEARVPVPSDLVLAVIDSAKECPGECIHVRRAGDKVLVAGPNAEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVV0</accession>
    <name>C7PVV0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786635.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2424"/>
    <dbReference type="MEROPS" id="U72.001"/>
    <dbReference type="EnsemblBacteria" id="ACU71342">
        <property type="protein sequence ID" value="ACU71342"/>
        <property type="gene ID" value="Caci_2424"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2424"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040524_1_0_11"/>
    <dbReference type="OMA" id="YFRGRCL"/>
    <dbReference type="OrthoDB" id="537546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019941">
        <property type="term" value="P:modification-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022366">
        <property type="entry name" value="Pup_deamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004347">
        <property type="entry name" value="Pup_ligase/deamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42307">
        <property type="entry name" value="PTHR42307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03136">
        <property type="entry name" value="Pup_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018077">
        <property type="entry name" value="UCP018077"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03688">
        <property type="entry name" value="pupylate_PafA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="503" mass="56843" checksum="96DF0DACC1B1FD23" modified="2009-10-13" version="1">MSVWRIMGTETEYGISVPGNPGANAMLISSQIVNSYAAAMHRARRARWDFEEENPLRDARGFDLARDIADASQLTDEDAGLANVILTNGARLYVDHAHPEYSSPEVTNPRDAVIWDKAGEWIMAEASRRAAEIPGTAPINLYKNNTDNKGASYGSHENYLMQRSTPFADIVRNLTPFFVSRQVVTGAGRVGVGQDGRAHGFQISQRADFFEVEVGLETTLKRPIINTRDEPHADPERYRRLHVIIGDANLAEISIYLKTGTTALVLAMIEERFMSTDLSVDSPVRTLHQVSHDPTLRQLVTLRSGRKLTAVQLQMEYCEQARKFVEDRYGSDVDDVTKDVLERWESVLTRLESDPMSLSRELDWVAKYEILQGYRKRDGLEWDSSRLELVDLQYSDVRPEKGLYQRLAARGRFERITTDEQIRAAVDHPPEDTRAYFRGRCLDKYADSVAAASWDSVIFDVPGRESLQRVPTLEPTRGTKQHVQALIDRSRTAEDLVRALTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW84</accession>
    <name>C7PW84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793061.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4469"/>
    <dbReference type="EnsemblBacteria" id="ACU73332">
        <property type="protein sequence ID" value="ACU73332"/>
        <property type="gene ID" value="Caci_4469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4469"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_11"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="272" mass="27880" checksum="FAF61796BFE9B8B5" modified="2009-10-13" version="1">MRADGLAGRTALITGAGSGIGRAVAVALAAAGARVIVAGRTAATLEQTVKLADEATAVWGGESLVRGQSWAPAVAAGAQAHIADVTDPAAVRALLVAVEREHGGLDIAVNNAGRPSWGPVARIAPAEWDAVLGVNLTGVWLCLQHELDLMRRSGGGAVVNIVSRLGIPTREENQNAYAASKAALSILTRTAAREYVGSGIRVNAVSPGPTDTAMTVWDQETPAERDERVARTVPIGRLAAPAEIAAAVRWLVSDEASYVVGHDLVVDGGLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW90</accession>
    <name>C7PW90_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Respiratory nitrate reductase, gamma subunit</fullName>
            <ecNumber evidence="15">1.7.99.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">Caci_4475</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.7.99.4" evidence="15"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793067.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4475"/>
    <dbReference type="EnsemblBacteria" id="ACU73338">
        <property type="protein sequence ID" value="ACU73338"/>
        <property type="gene ID" value="Caci_4475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4475"/>
    <dbReference type="eggNOG" id="COG2181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092378_0_0_11"/>
    <dbReference type="OMA" id="MVSGGFF"/>
    <dbReference type="OrthoDB" id="1873056at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023234">
        <property type="entry name" value="NarG-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003816">
        <property type="entry name" value="Nitrate_red_gam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02665">
        <property type="entry name" value="Nitrate_red_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00351">
        <property type="entry name" value="narI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrate_red_gam" evidence="14">
        <location>
            <begin position="3"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACU73338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="27035" checksum="5A3CC72A438C4902" modified="2009-10-13" version="1">MQTFLWGALPYIAIAILITGLVWRYRYDKFGWTTRSSGSYERRILNIASPMFHYGILFVLVGHLMGLFVPSAWTDALGLTEHGYNLLSLFAGTAAGALAVIGILMLIYRRRTTPAVFRATTRNDKLMYVVLLAAIIMGLVAKLTHAGLHEGYDYRATIAPWARSLSWLQPKTALMAQAPVVFQIHAVIGLLLFALLPFTRLVHMFSAPIQYLFRPYIVYRSRDSRALGEAPVRRGWEGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWX2</accession>
    <name>C7PWX2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulatory protein GntR HTH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796954.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8406"/>
    <dbReference type="EnsemblBacteria" id="ACU77229">
        <property type="protein sequence ID" value="ACU77229"/>
        <property type="gene ID" value="Caci_8406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8406"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="CERIAAQ"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="277" mass="29475" checksum="778032C17745D7A0" modified="2009-10-13" version="1">MYVEGWNVHRVIRPARLANAVVERLLLRILEGEFPPGTDLPPEAALAAEFAVSRTILREALKALEEKRVLRIRHGRGTTVRPKAEWNLLDPLVLSVQLEYESSPELVAELGEVRTALLTLMAELAARRVHPPQREQLAAALERMRAAVEDPGPFHEAATAFTRTLAEAAGNEVARCVIETIDVPHGGQDDNPAKLIETMKLRLLLAEAAHATVAAGPGAPAGSAPVPAPTSSPAAPGAPVPAPATAPGAQPLRQGQAATVPLNRHGVRTPMPQSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWX8</accession>
    <name>C7PWX8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8412"/>
    <dbReference type="EnsemblBacteria" id="ACU77235">
        <property type="protein sequence ID" value="ACU77235"/>
        <property type="gene ID" value="Caci_8412"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8412"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OMA" id="LDRFAPM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="22"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="167"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="25750" checksum="6FD7C1E985BEEE59" modified="2009-10-13" version="1">MSQTTPEPTEAPGSADPAAPIRIVLVDDQELLRTGFRMVLNSQPDMAVVGEAGDGQVALDLLTRLQADVVLMDVRMPRLDGVAATREIVVRGERPRVLMLTTFDLDEYAFTALKAGASGFLLKDVPPPDLLAAIRAVHSGEAVVAPSTTRRLLDKFAPMLPSESEPAPPELTVLTDREHEVLLLVAQGMSNAEIAGKLFLSEATVKTHVGRILMKLGLRDRVQAVVLAYETGLVKARGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWZ6</accession>
    <name>C7PWZ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796978.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8430"/>
    <dbReference type="EnsemblBacteria" id="ACU77253">
        <property type="protein sequence ID" value="ACU77253"/>
        <property type="gene ID" value="Caci_8430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8430"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_0_2_11"/>
    <dbReference type="OMA" id="YRLRHLR"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="50"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="298" mass="32924" checksum="C4AE9BBF8E593D42" modified="2009-10-13" version="1">MSQDIELYDYRPITEREPLSWPGGNRVAFYVGLNIEHFYVDLPGTATYEGTTALTPDSLNYGWRDYGPRVGIWRQIKLLDKHGVKASALLNSDVAARYPQIIEAGVRRDWAWLGHGASNSHLFTGLERDVEQGEIREVLRTIEQATGVKPRGWMGPGLIETFHTPELLAAEGVEYVLDWTNDDQPYPTNVPGLLSLPYSVELNDIGVFVSKGLSGPDFVQMVKDQVDQLYEDAADGSGRVMALALHPFITGQAFRTRYLDEALAYVVNHPGVWTTTADAIADHYLAVTGQAAASRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX50</accession>
    <name>C7PX50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0449"/>
    <dbReference type="EnsemblBacteria" id="ACU69401">
        <property type="protein sequence ID" value="ACU69401"/>
        <property type="gene ID" value="Caci_0449"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0449"/>
    <dbReference type="eggNOG" id="COG3764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083535_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="216" mass="22432" checksum="2B0ABE1FF2C0CE50" modified="2009-10-13" version="1">MLRAGVPVAVLAIPSVGVDEVVGEGTGAAVLESGPGLRRDTVLPGQAGTSVIMARASGYGGPFRYLDQLQPGDRVEVTTGQGVADYRVSDVRRRGDPEPARLHGQLGRLTLVTASGAAYTPNGALYVDADLISDVQPTPPAPVPHPGAEESAMGEDRYARPDVAAWTAVLAGATVLAFWAGPRWGRAKTWLVAVPVLLVVGLTLADRIALLLPNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP2</accession>
    <name>C7PXP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2577"/>
    <dbReference type="EnsemblBacteria" id="ACU71495">
        <property type="protein sequence ID" value="ACU71495"/>
        <property type="gene ID" value="Caci_2577"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2577"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024648_7_0_11"/>
    <dbReference type="OMA" id="IHQPGVA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="41604" checksum="6A2517D0848F3D44" modified="2009-10-13" version="1">MYDVIIVGARCAGAATALLLARQGVRVLLADRTTFPSDTVSTHLLHPAGVARLREWNLLEPLLATGCPPLDAISYHAAEDLVLRGAPYAYEDVTISVAPRRTVLDALLVEAAVAAGAELREGASLRNVLWEDGRVVGAEFGSGADSSGGSGVFTERASLVIGADGRHSTVAREVGAKLVRDAGTFGCQFYGYWSGLPDEGTQIFIGGGQAVLAYPTHDRHHLVLVGWPHARFAEVKQDIDRHFLAAVATSAPAVREHLTDDARSERITGSGDLANYVRESSGPGWVLVGDAAMAKDAVTAQGIGDAFSQAQSLAERLPAALAAGPRAVDASTAAHVADRDRDGATAFETTVAFAMGGNSSELLPVLRAIADRPDLVSMFYGIYAGRVTMDEFAAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU8</accession>
    <name>C7PXU8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793137.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4545"/>
    <dbReference type="EnsemblBacteria" id="ACU73408">
        <property type="protein sequence ID" value="ACU73408"/>
        <property type="gene ID" value="Caci_4545"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4545"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_7_0_11"/>
    <dbReference type="OMA" id="QIDEAMH"/>
    <dbReference type="OrthoDB" id="1972497at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="22406" checksum="E37B7DD42E3C66DC" modified="2009-10-13" version="1">MSPRDQIVPAQPQDATALSRVIARAFHDLAPSVWLIPDSEGRTRLFPGYFRLFVDEAMARGRVYTTLELTAVALWLPSTPNEEPDSSGYDAGLPSATGIWVDRFRIFDALLAEHHPHDTAHDHLAILAVDPHHQHQGIGSALLAAHHDHLDAEDPPRAAYLEASDATTRELYLRHGYTDLDDPIILPSGAHMYPMLRRTNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXY4</accession>
    <name>C7PXY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793173.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4582"/>
    <dbReference type="EnsemblBacteria" id="ACU73444">
        <property type="protein sequence ID" value="ACU73444"/>
        <property type="gene ID" value="Caci_4582"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4582"/>
    <dbReference type="eggNOG" id="ENOG502ZPBD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1178535_0_0_11"/>
    <dbReference type="OrthoDB" id="2028188at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981337" evidence="2">
        <location>
            <begin position="29"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="23274" checksum="C1372FEB2FDC4366" modified="2009-10-13" version="1" precursor="true">MHAKLIALIVVLGSAAGGCASTATGSAAQPSGSPSPTSTQSSSAKPSTPSTPTTQATPSTPSAPPTTTVTVTKPPPAPAATATSPAATPAPTAQDPEAVVSAFYAAINAQDYATAWKLGGSNLGSSYSDFAAGFAGTAHDSLTITGVQGNTVDVHLEALQSDGSTKVYDGFYIVSNGAITEGRLSQSATTVAPTSPSALPQRGEFCPDADAGLTAQDASGNTLTCVYESGAFHWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY06</accession>
    <name>C7PY06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793195.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4604"/>
    <dbReference type="EnsemblBacteria" id="ACU73466">
        <property type="protein sequence ID" value="ACU73466"/>
        <property type="gene ID" value="Caci_4604"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4604"/>
    <dbReference type="eggNOG" id="COG1741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_5_1_11"/>
    <dbReference type="OMA" id="TPWHPHR"/>
    <dbReference type="OrthoDB" id="833478at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="45"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="4">
        <location>
            <begin position="203"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="331" mass="35100" checksum="01440E74F7AFA141" modified="2009-10-13" version="1">MPAVTVENPLALPRIAAVAPDATPRPVLAVATAPSGFEGEGFPVHRAFAGIRSEYLDPFIMMDQMGEVEYAAGEPKGTPWHPHRGFETVTYIIDGTFVHQDSHGGGGVITDGDTQWMTAGSGLLHIETPPEKLVQSGGLFHGIQLWVNLPAAKKWSPPRYQDIRSGQVGLASSQDGGALVRVIAGGIDGVQGPGSTHTPITLAHLSITPGARVELPWRKDFNALVYVLNGRGTVGDQSRPVKSAQAAVLGAGDSIVIAADQQQEGRHPTMDVIVLGGEPIREPVVHYGPFVMNTEDEIRQALLDFRSGKMGVEPTEAIPHIQPGDTPPPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYF3</accession>
    <name>C7PYF3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHOCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6597"/>
    <dbReference type="EnsemblBacteria" id="ACU75443">
        <property type="protein sequence ID" value="ACU75443"/>
        <property type="gene ID" value="Caci_6597"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6597"/>
    <dbReference type="eggNOG" id="ENOG5032Y5M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164081_2_0_11"/>
    <dbReference type="OMA" id="GRWAQQD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHOCT" evidence="2">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="9941" checksum="BDE79F77D16C4C86" modified="2009-10-13" version="1">MGLLRGVARTAVVAGTATAVSNRVSRRQGGRWAQQEAAAQPAQAPPPAAAPAPAPQTPQAPSMDDKLAQLKDLGDLKESGVLSEAEFAAQKQKILGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYI9</accession>
    <name>C7PYI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797036.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8488"/>
    <dbReference type="EnsemblBacteria" id="ACU77311">
        <property type="protein sequence ID" value="ACU77311"/>
        <property type="gene ID" value="Caci_8488"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8488"/>
    <dbReference type="eggNOG" id="ENOG5032WU7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166724_0_0_11"/>
    <dbReference type="OMA" id="CKGEVIL"/>
    <dbReference type="OrthoDB" id="1884729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="13699" checksum="B75AF1343BD64032" modified="2009-10-13" version="1">MPTATRIAKVFDGATDGVPFYLPDHPRLSPTERTAPLSYLAAGTALLMTTASEPDFVEPSRGEVVPMNFRTDGTWVWNDALAYYLAEYGLAPEPEFLAAMEAADWVCPTPEIEVVETALEELFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYS6</accession>
    <name>C7PYS6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV secretory pathway VirB4 protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8579"/>
    <dbReference type="EnsemblBacteria" id="ACU77398">
        <property type="protein sequence ID" value="ACU77398"/>
        <property type="gene ID" value="Caci_8579"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8579"/>
    <dbReference type="eggNOG" id="COG3451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009097_4_1_11"/>
    <dbReference type="OMA" id="TEYRKLE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="252"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="2">
        <location>
            <begin position="436"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="595" mass="63497" checksum="EF4C3C7DF9EF1949" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ31</accession>
    <name>C7PZ31_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784882.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0651"/>
    <dbReference type="EnsemblBacteria" id="ACU69587">
        <property type="protein sequence ID" value="ACU69587"/>
        <property type="gene ID" value="Caci_0651"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0651"/>
    <dbReference type="eggNOG" id="COG4762">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080841_1_0_11"/>
    <dbReference type="OrthoDB" id="1586328at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018960">
        <property type="entry name" value="DUF1990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09348">
        <property type="entry name" value="DUF1990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1990" evidence="2">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="21577" checksum="377B4BE5AC09EB6B" modified="2009-10-13" version="1">MTPTPTPTPPPHPGDAALGPTPDGHRYFRRSIPLAHSFDPQDASLDRAFERARAMLQSWGPQLGAGMRIEFAAASDADADADADADGGQAFALPSPSVGLEGQLVSRVAGLIPLRAPFRVITAEFASTDHAGYAYETLPGHPERGREAFYVTRAEGLVEFTVMAFSQPVVWYARLGGPVTRIIQNRYTNKYLLAMAVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZG9</accession>
    <name>C7PZG9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">(5-formylfuran-3-yl)methyl phosphate synthase</fullName>
            <ecNumber evidence="3">4.2.3.153</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:43536"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:83407"/>
            <dbReference type="EC" id="4.2.3.153"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.3.153" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786919.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2711"/>
    <dbReference type="EnsemblBacteria" id="ACU71626">
        <property type="protein sequence ID" value="ACU71626"/>
        <property type="gene ID" value="Caci_2711"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2711"/>
    <dbReference type="eggNOG" id="COG1891">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068659_0_0_11"/>
    <dbReference type="OMA" id="NFPWVIR"/>
    <dbReference type="OrthoDB" id="1796491at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007565">
        <property type="entry name" value="4HFCP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04476">
        <property type="entry name" value="4HFCP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015957">
        <property type="entry name" value="UCP015957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015957-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="26283" checksum="FF5DE0F4E347482F" modified="2009-10-13" version="1">MLLLISPADVEEARDCAKASRHLDIVDVKKPDEGSLGANFPWVIREIRDIVPADKPVSATVGDVPYKPGTVAQAALGAVVSGATYIKVGLFGCTTPDQAVTVMRAVVRAVKDYRPDALVVASGYADAHRVGCVNPLAVPDIAGRSGCDAAMLDTAIKDGTRLFDHVPPDLCAEFVRRAHDTGRLAALAGSVRAEDLGTLTAIGTDIVGVRGAVCERGDRTTGRIQPHLVAAFRAEMDRHSREQAAVPAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZQ7</accession>
    <name>C7PZQ7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793301.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4711"/>
    <dbReference type="EnsemblBacteria" id="ACU73572">
        <property type="protein sequence ID" value="ACU73572"/>
        <property type="gene ID" value="Caci_4711"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4711"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_3_2_11"/>
    <dbReference type="OMA" id="RIKFVEF"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039369">
        <property type="entry name" value="LacA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43017">
        <property type="entry name" value="PTHR43017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="5">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="199" mass="21698" checksum="13C7F8542F57F1DC" modified="2009-10-13" version="1">MSQHHEKVLERIRLGLVYTETEAAFQAPQRRTEEIFEYNHTPPGDPGRRRALLEAILGSVGERTVLLPPFHAGFGSNVHLGDDFFGNVNLTFVDDVEIRIGHGVMIAPSVTLTTTGHPVHPSRRADFGRFSEPIVIEDKVWIGSNAVVLPGVRIGYGSVIGAGSVVSHDIPAMTVAVGTPCRVLREITEEDLKTRTAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZV2</accession>
    <name>C7PZV2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793346.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4756"/>
    <dbReference type="EnsemblBacteria" id="ACU73617">
        <property type="protein sequence ID" value="ACU73617"/>
        <property type="gene ID" value="Caci_4756"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4756"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_0_1_11"/>
    <dbReference type="OMA" id="TYWVRRA"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="320" mass="34411" checksum="6A12D4B5B60E3D8E" modified="2009-10-13" version="1">MRILMLGGTGFVGRAVVEDALARGHDVTIFSRGRSGAGLFPQVARLVGDRDGDDYAALATGAWDAVVDSSAYVPRHVNNAMDALGDRVGRYVFVSSHAVYPRRGVAAGSTEDTPRRAPVRDTEELLEETYGPLKVACEDDIQARFGERASIVRLGKVAGPHDPQNGLTYYVRRAAAGGRLALPGRPEQPVQLIDSRDAARLMVRLIEDDRGGAFNAVGPGTPITLADTIHICARVAGTEVEIVPVPEQDAQGTFFPLIRDPAEWNVMQRDPARAVAAGMPQTPFETTVADVLAWDRERGTPPLKFGFTAEEEAKALAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q081</accession>
    <name>C7Q081_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795303.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75574">
        <property type="protein sequence ID" value="ACU75574"/>
        <property type="gene ID" value="Caci_6728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6728"/>
    <dbReference type="eggNOG" id="ENOG5032ZHB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117657_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025361">
        <property type="entry name" value="DUF4265"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14085">
        <property type="entry name" value="DUF4265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="19030" checksum="478A6039D4FB3274" modified="2009-10-13" version="1">MATANGQQTSGTSRTTFEVAFDLSPEAPDWPPVAVERLWGERTAVDSELRLLNVPFFARGVAYGDLVHVRPDHDRRELVFERLNGESGHSTVRITLLDGRARRDVQDRLRAAGCSWETAAQFAALLAVDVPADGDYRALRDWLTARSGEGAIEFQESAISARHLEQVPNFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0B5</accession>
    <name>C7Q0B5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8632"/>
    <dbReference type="EnsemblBacteria" id="ACU77448">
        <property type="protein sequence ID" value="ACU77448"/>
        <property type="gene ID" value="Caci_8632"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8632"/>
    <dbReference type="HOGENOM" id="CLU_2932785_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="60" mass="6026" checksum="FF69E701F1F3198B" modified="2009-10-13" version="1">MQYALEMTGWVMPGAMFSYSGSGSGSNTDTDADYRHAAPQGDPAVANGGARRASGVAGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0E3</accession>
    <name>C7Q0E3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative chaplin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797200.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8661"/>
    <dbReference type="EnsemblBacteria" id="ACU77476">
        <property type="protein sequence ID" value="ACU77476"/>
        <property type="gene ID" value="Caci_8661"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8661"/>
    <dbReference type="HOGENOM" id="CLU_145456_3_1_11"/>
    <dbReference type="OMA" id="NLEANIC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="1" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982756" evidence="3">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="4">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="7458" checksum="DD181E261D2901F5" modified="2009-10-13" version="1" precursor="true">MSMRKTLVAAAFAAVAVLGTAGTASASGAGAIGGAIGSPGLLSGNNIQIPINIPINLCGNDISVLAALTGAAGNTCVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q106</accession>
    <name>C7Q106_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkanesulfonate monooxygenase</fullName>
            <ecNumber evidence="2">1.14.14.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.14.5" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2768"/>
    <dbReference type="EnsemblBacteria" id="ACU71681">
        <property type="protein sequence ID" value="ACU71681"/>
        <property type="gene ID" value="Caci_2768"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2768"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_1_4_11"/>
    <dbReference type="OMA" id="IDEFMIV"/>
    <dbReference type="OrthoDB" id="919913at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="374" mass="40041" checksum="98CEFAD072FBC311" modified="2009-10-13" version="1">MSNPSKHIEFIGITGTRPGSESETALADGPVIQPGYLQELALAHEESGFDRVLIAHSSASPDGFVIADQVLSRTSRIGVLLAHRPGFVSPTYAARKYATLDAFHPGRVALHTITGGDDREQARDGDLADKATRYRRTDEFLAVVRKEWESADPFDFEGEFYTVRGGWSAIRPEPGAIPVYFGGASEDAIRVGGKHADVYAFWGEPLAGIAERIGEVRAAAAPFSRDPRFSVSLRPIPAATEAEAWDRAAEVLRLTKERAGQARKAWGWGGDKKDFAAARGSQRLLEYAAAGDVHDKRLWTAVAKETGAAGNSTALVGSYEQVAEALLEYVALGVSTLLIRGFSPLADARDYGTLIGLVRAQHENAPLAGVGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q157</accession>
    <name>C7Q157_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2823"/>
    <dbReference type="EnsemblBacteria" id="ACU71732">
        <property type="protein sequence ID" value="ACU71732"/>
        <property type="gene ID" value="Caci_2823"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2823"/>
    <dbReference type="HOGENOM" id="CLU_1159467_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="26543" checksum="46713B1E41770E4C" modified="2009-10-13" version="1">MSESPDRPPITAAAPFSLDLPKPNLDGAHWFPTAALAREALHEYAYRVHELAAERDALIRGAIAADVPVSAISTITGIARSTINRIEPRPVAEPVDEETLRTYAGLLNQRAQRIATRAPQGSGVGDDAERYFLDGYVQVTREEAVSWLSDSSPHDNPHGDRVLHRAIQLEAQTSQSRASQLTRRFRSPVDRWTGWIAYGRDDARDRIARELRLIRGGMSPLSMFTQEEREAAEVPPEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1V3</accession>
    <name>C7Q1V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Propionyl-CoA carboxylase</fullName>
            <ecNumber evidence="4">6.4.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6813</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.3" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795382.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6813"/>
    <dbReference type="EnsemblBacteria" id="ACU75654">
        <property type="protein sequence ID" value="ACU75654"/>
        <property type="gene ID" value="Caci_6813"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6813"/>
    <dbReference type="eggNOG" id="COG4799">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018822_6_2_11"/>
    <dbReference type="OMA" id="QGGAMGR"/>
    <dbReference type="OrthoDB" id="886663at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="3">
        <location>
            <begin position="233"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="486" mass="50043" checksum="48A7AE708B2FB0AA" modified="2009-10-13" version="1">MTVTDTQAAPAIPAPAAKPSRDDDPRNPAKRLERLFDAGTTELLTPVDDSGFLAAAGLIDGVRTVAYASDATIQAGAMGRTGCQVILAAYEHALAGGHPIVALFHSSGARLQEGVASLHAVGQVFAAMTRASGKIPQISVVLGPAAGGAAYGPALTDIVILGPAGRIFVTGPDVVRSVTGEDVDALRLGGPEPHGRRSGVVHVVADTDDAAYSSARKLAALLGDQGTLDAASVEDRDLAHLLPASPKRAYDVHPLVNAVFDKAGVELHTKWAPNVVTALGRFGGRTVGVIANNPLRLGGCLDSAAAEKAARFVRMCDAFGVPLIVLVDVPGYLPGVGQEWDGVVRRGAKLLHAFAECVIPRVTLVTRKTYGGAYIAMNSRALGATKVFAWPTAEVAVMGSVAAVRIIHRRKLADVSDDIRAQMEQELAAEHEKVSGGVDRAIEIGVVDQVVEPGASRSAIAAAIAAAPGGLGGDALVRGQHGNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q206</accession>
    <name>C7Q206_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797267.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8728"/>
    <dbReference type="EnsemblBacteria" id="ACU77543">
        <property type="protein sequence ID" value="ACU77543"/>
        <property type="gene ID" value="Caci_8728"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8728"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454698_0_0_11"/>
    <dbReference type="OMA" id="NLADEMV"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981381" evidence="1">
        <location>
            <begin position="30"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="186"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="554" mass="54972" checksum="5CC2CBF91AB3ACAA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2T5</accession>
    <name>C7Q2T5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787120.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2918"/>
    <dbReference type="EnsemblBacteria" id="ACU71827">
        <property type="protein sequence ID" value="ACU71827"/>
        <property type="gene ID" value="Caci_2918"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2918"/>
    <dbReference type="HOGENOM" id="CLU_1507989_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="178" mass="20623" checksum="1A33947E6C3EB73F" modified="2009-10-13" version="1">MTDTSATNPEWIPVWYGYDREFLVRFTDADNRRHDWHVRSDNFDGTGRRRHMAWHAWPDIPDPERWDKPVFLHRRLADAKDEFALVVMQGWRRGFGYTESVTGSPIYGRDSARRERRFLVAELHGRGICPRCGKLVHVRTDGMLNAHNRPRSLDRCDGTHGPAVAELKTLAQMAEAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3G9</accession>
    <name>C7Q3G9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6896"/>
    <dbReference type="EnsemblBacteria" id="ACU75734">
        <property type="protein sequence ID" value="ACU75734"/>
        <property type="gene ID" value="Caci_6896"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6896"/>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078491_2_0_11"/>
    <dbReference type="OMA" id="PEAEANW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="63"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="22089" checksum="3D7DF06627C6D3B9" modified="2009-10-13" version="1">MSRLKMPSRASSRVPTARSPHDAVRAVAAGRRRRVPYVVAGSMLVLGAVVVGAVAFVKVGGRVPVLVVGAPVQVGQVISADDLKVVDIAPGTLAHVAFADEEKQVVGQPAAVPLVPDEVLTWQLIGAASYPPAGYGVATTQMKAGAYPPHLVAGARVEVVAPASAAGAAAQVVASLAAVTEVSTPTDSGDVVVSVLADQNSAKAVSSATPGSLSLVLLPAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3I4</accession>
    <name>C7Q3I4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75749">
        <property type="protein sequence ID" value="ACU75749"/>
        <property type="gene ID" value="Caci_6913"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6913"/>
    <dbReference type="HOGENOM" id="CLU_2615525_0_0_11"/>
    <dbReference type="OrthoDB" id="1619566at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="8903" checksum="232B73FE622ECC4E" modified="2009-10-13" version="1">MTVRLNETMAFYEPELGFVEAVIMRAQPWGWWTGHKLEIPEDYLQAFTTADKKADALIYLDLFAGWPTNKDAAPASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M7</accession>
    <name>C7Q4M7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycine betaine/L-proline ABC transporter, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_3087</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787289.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3087"/>
    <dbReference type="EnsemblBacteria" id="ACU71996">
        <property type="protein sequence ID" value="ACU71996"/>
        <property type="gene ID" value="Caci_3087"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3087"/>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_2_2_11"/>
    <dbReference type="OMA" id="AKRYPYQ"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="369"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU71996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="45803" checksum="B1308D723CC2CB93" modified="2009-10-13" version="1">MISFVQVGKTYPDGTVAVAATDLTAESGRITVLVGPSGSGKTTLLRMVNRMIDPTSGEILIDGVDVRSKSAPELRRGIGYVIQNAGLFPHRTVLANVMTVPRLLGWSREKARERAMELLTTVGLEESHAKRYPFQLSGGQQQRVGVARALAADPPVLLMDEPFSAVDPVVRKDLQTELLRLQSELSKTILFVTHDIDEAIQLGDKVAVLNTGGLLEQFDTPTELLAHPKNAFVESFLGLDRGVRRLSFFSSSGVPLRPEPVVARSAPPAEVLARKGSQPWLLVVDEAHRPLGWLPADQVPGDGDLGSVPVGDLTSYGHTFDAETDSLRAALDSAILSPSSRAVGVGDDGRVIGVASVEELVPAIRAAQDGSAQATIHGNPEIGEGGAADAGAGVDEAGSTSPGQFGNPATGQVDLPVADQADRPETGEDSNPETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S5</accession>
    <name>C7Q4S5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mandelate racemase/muconate lactonizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793602.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5013"/>
    <dbReference type="EnsemblBacteria" id="ACU73873">
        <property type="protein sequence ID" value="ACU73873"/>
        <property type="gene ID" value="Caci_5013"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5013"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_3_2_11"/>
    <dbReference type="OMA" id="PRWCFLK"/>
    <dbReference type="OrthoDB" id="1825548at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008869">
        <property type="term" value="F:galactonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03325">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023592">
        <property type="entry name" value="Galactonate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00003">
        <property type="entry name" value="D-galactonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00908">
        <property type="entry name" value="MR_MLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="125"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="381" mass="41709" checksum="BB1F31A66C116A2A" modified="2009-10-13" version="1">MKITSLETFLVAPRWLFLRIGTDEGLAGWGEPVLEGRAETVRAAVAELSEYLIGEDPLRLEHHWQVLTKGGFYRGGPVLSSAVAGIDQALWDLAGKTYGVPVHQLLGGPVRERARVYAWIGGDRPTQVAELAAEQVEAGFTAVKMNGSAQMRHIDTPAATAAVTARVAAVREVLGADRDVVVDFHGRMSTAMSRRLLRMLEPLQPLFVEEPVLPENSRDLRSLAESSGVPLAVGERLYSRWDFRDVLPSGIAVAQPDVSHAGGISELRRIAAAAETYDVAMAPHCPLGPIALAASLQVDFATPNFLIQEQSLGLHYNRGNEMLDYLLDPEPLRVRDGHIDRLTGPGLGIEIDEAAVRRADETGHHWRNPVWHHQDGSFAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5A5</accession>
    <name>C7Q5A5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795602.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7044"/>
    <dbReference type="EnsemblBacteria" id="ACU75874">
        <property type="protein sequence ID" value="ACU75874"/>
        <property type="gene ID" value="Caci_7044"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7044"/>
    <dbReference type="eggNOG" id="ENOG50342WT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_577080_0_0_11"/>
    <dbReference type="OMA" id="GMRTHLC"/>
    <dbReference type="OrthoDB" id="626964at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="51734" checksum="B5B1ED19A447276C" modified="2009-10-13" version="1">MADLPVAPLDATTRTLCAQTYWDMAFAREAEELLLGTGFSAIGPPVGLNLPSILQHAEHSLRIRRRRDWALLACWLLAVFCVAGPLLVTRGTKDFLPALFGVACGLGSVGALAWTVATAARWIRVHSAFALLRTSASPLASAPPLPPDVHGEIVADQGSNVVCYAAASPTPFAGFGELVDDKVMVHLPLVLVPAYVEGAGTKDTHHVDATDLHLYLRNEMSRDSGVRDLTIVSNLFVRGDAANGVAGLWPGGKEARPSRQAHALIYSAGINDPGDRAQTYLTLQAIRHGGNLVVSMHVRLREQHERISLEIASAIAAPLAGKYTTVGGALPRSLGGLRAHARWYALMELPAALTEAWSGPVIRFVIRRLRLRARLDILRGIRSGRMPDRGARTSLRRWTMDPAKIQYQEEADARDILQRLRKALFDHLVNYFEMHKISTGELMRIRENVLIVEMKFRGEVIDGARAFGANEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5W0</accession>
    <name>C7Q5W0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785351.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1131"/>
    <dbReference type="EnsemblBacteria" id="ACU70057">
        <property type="protein sequence ID" value="ACU70057"/>
        <property type="gene ID" value="Caci_1131"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1131"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_0_11"/>
    <dbReference type="OMA" id="GGIGWKV"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="46192" checksum="FFE9B7BD71F181F9" modified="2009-10-13" version="1">MTATTTLEILSRDFSGDIIEPGHAEYAAASGVVLAAGAPAVILRPSSVGGVQAAVRHAAASGLPLAVRGGGHSFGGFGTNDGGVVIDLSRLCGVEVVAGGWNVVRVGGGATWGQVTAALKPHRLALSSGDTKGVGVGGLTLGGGIGWKVRKYGLALDSLVRVEIVTADGHVVTADEDENADLFWAVRGGGGNFGIVTAFEFAGHPTTDVFHGKISFPGAEAATVIPAWAEYMRTAPEALTTIAVFANPFAGPGAPVEILVTFDGDATDEADAAIDPLRRLGTLIDDDITLKPYGDVLEEAPPLPPALRFHTRNAFVERAGVDAALRIMTEAGAAPGAPFLTARSLGGALARVPDDATAFAHRRAELMIGTALVGPEPVIEAAIPALDALWERLTPHVNGTYPNFNTTATDQEIAAAYPTDTYKRLAAVKRHYDPANLFTANYNVLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5X7</accession>
    <name>C7Q5X7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785368.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1148"/>
    <dbReference type="EnsemblBacteria" id="ACU70074">
        <property type="protein sequence ID" value="ACU70074"/>
        <property type="gene ID" value="Caci_1148"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1148"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="KHMVDAG"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="26559" checksum="1F34A2AB825A2769" modified="2009-10-13" version="1">MTDPTASTSALDTPRTAIVTGAARGIGAAVAARLAADGHAVAVVDLDETACADTVAAIAKAGGKALAVGCDVSVEEQVAAAVERIAVELGAPTILVNNAGILRDNLLFKMTVGDWDAVMNVHLRGAFLMSRAAQKHMVDAGFGRIVNLSSTSALGNRGQANYAAAKAGMQGFTKTLAIELGKFGVTANAIAPGFIETDMTKATAARMGVDFDVFREVAISQIPVGRSGKPEDIAAVAAFLVREDAGFVSGQVIYAAGGPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q655</accession>
    <name>C7Q655_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787354.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3152"/>
    <dbReference type="EnsemblBacteria" id="ACU72061">
        <property type="protein sequence ID" value="ACU72061"/>
        <property type="gene ID" value="Caci_3152"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3152"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_643470_0_0_11"/>
    <dbReference type="OMA" id="VVRSAMF"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="396" mass="40481" checksum="D1AB2F8BD9E6CE55" modified="2009-10-13" version="1">MLRGAQAAGRFAGRAGIPGRPVRGWLVRERLDDGAEYVVALPLAFQIGVLPAAALVYVGSFGGSGSGTVLGLCAALILATGALWLGAARGVPTRTVLGADSALAIAGNLAMSTVSAPSARAAEVSWQYFAGCVALWTLARGVAGGLGAVAVGAVVRSAMFAGTGSGVVVPVFLGDVAVLLIAVLMAAGVLALLHRDAERLRTGVRRSLHDTVLQTLEAIALTLPGDAENAARRLREVRAIAHAEAVALRRELSRRSEARTTPGVVEGLVALGTELAREGLRMRLDAAEGVDGDDGLTPQRRAAVLAAAREALRNVLKHSGVGEALVRVWDEPDGLTLVVRDFGVGFDPEAHRPGFGLSESVAARMAEVGGTAGVGSRVGNGTSVTLWVPVAGEEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q663</accession>
    <name>C7Q663_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS116/IS110/IS902 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787362.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3160"/>
    <dbReference type="EnsemblBacteria" id="ACU72069">
        <property type="protein sequence ID" value="ACU72069"/>
        <property type="gene ID" value="Caci_3160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3160"/>
    <dbReference type="eggNOG" id="COG3547">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036902_2_3_11"/>
    <dbReference type="OMA" id="KQSIHHI"/>
    <dbReference type="OrthoDB" id="655500at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="11"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="399" mass="43108" checksum="827337E976698A02" modified="2009-10-13" version="1">MYDTSGIGVFLGLDVGKGEHHGHGLTPAGKKVFDKQLPNSEPRLRQVFDKLKAKFGTVLVIVDQPANIGALPLTVARDCGCEVAYLPGLAMRRLADTYEGEAKTDARDAFVIADVARTNPRTLRQITVTDQTEAELAMLVGFDDDLAGESTRTSNRLRGLLAQIHPSLERVLGKRIRHPAVLELLSRYGSPQQLHQAGGDQIAAVLKPKAPRMAARLAAEITTALAEQTVVVPGTTAAEVIVPSLARQLAEILTQRDALEGRLAALLEAHPLHRLLTSMPGVGVRIAATVLITIGDGRTFPDADHLASYAGLSPATKSSGSSIKGEHAPKRGNRQLKRAMFLSAFAALHDPASRDYYDRHRNSGKTHTQALLRLARRRITVLFAMLRDGCLYESRPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6A9</accession>
    <name>C7Q6A9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3208"/>
    <dbReference type="EnsemblBacteria" id="ACU72115">
        <property type="protein sequence ID" value="ACU72115"/>
        <property type="gene ID" value="Caci_3208"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3208"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_10_0_11"/>
    <dbReference type="OMA" id="RWEFHTF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="12"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="147" mass="15460" checksum="F66F54B4EBDEA2E7" modified="2009-10-13" version="1">MFELGTDGPLVIMAGVDGSESSVRAAAYAAGLARRQGAKLALVFIQPYPASVSASAASEMIAAGRATAEDLRRQMEEAIERLPVGTVARWEFYTGEGDPFRGLCDFAVKLRADAVVIGASQKTGHRIVGSVAVRLVKAGKWPVTVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6I5</accession>
    <name>C7Q6I5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793749.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5161"/>
    <dbReference type="EnsemblBacteria" id="ACU74020">
        <property type="protein sequence ID" value="ACU74020"/>
        <property type="gene ID" value="Caci_5161"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5161"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_9_4_11"/>
    <dbReference type="OMA" id="CATGFHQ"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="470" mass="49993" checksum="3980CE805234AB0C" modified="2009-10-13" version="1" precursor="true">MQIAVIGAGIAGLAATKVLTAVGHEVTTFDTEPEFGGVWSPTRHYPGLTTQNTRMTYEYSDHPAPASWPDYPSAEQWHSYLRSYVDRFGIAANLRLGTGVTLAEPTAAGWKVSLDSGESVEAAHLVIANGVFSRPAIPDWPGRAGHADAGGVVKAPSQHLTLDDARGKHVVVVGFGKSACDTAMALSTVAASVTMVPRRLLWKATKVLAGKHFEDVAMTRLGETLFANPRRFGPLFGAVSRATVKKHGLAAIGLIPPGRFDDIASSSASMATDGFFDAVRAGTIAVRRDRSIVELRGQDGPQAVLDDGSVLAADLIVAATGFVQSVPFLGSPLSAQNADGDFELFRNVLPHDIPNLTFAGYNTSLISSLSAEVGTTWIAAHLAGALTLPSPTARKVQVGADLEARKARMRGKYASGTVVLPRSLGNIDHMLSDMHAVLPWRVRMAQWTRRSYSTDFRETLGAAWRTLGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6Z5</accession>
    <name>C7Q6Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795736.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7179"/>
    <dbReference type="EnsemblBacteria" id="ACU76008">
        <property type="protein sequence ID" value="ACU76008"/>
        <property type="gene ID" value="Caci_7179"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7179"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1544850_0_0_11"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="41"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="173" mass="18718" checksum="12BAC667E265F134" modified="2009-10-13" version="1">MQQSRGTEPFDTGRTVRRKHGARPERAQPDRSRVNSLSWSFPGTPADVSCSRHWLAIAATEAWGECEDTDRLVLAYSEIATNAVVHGAGPVTVAAQICATSARCEIADRSTRLPKVRHATAGDLGGRGLEMVELTVDRLRVAADEVGKTVSFEVGRRDERDESGSPAEDDTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q703</accession>
    <name>C7Q703_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative anti-sigma regulatory factor, serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795744.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7187"/>
    <dbReference type="EnsemblBacteria" id="ACU76016">
        <property type="protein sequence ID" value="ACU76016"/>
        <property type="gene ID" value="Caci_7187"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7187"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116681_1_2_11"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="16949" checksum="C8DC04B7840F23D5" modified="2009-10-13" version="1">MDPEAHSLRTSAGIETGSDLDGEAGTEAETVVIQVPADADYLPIIRSASAHVATKLGCTLSEVADLRLAVDEACGLLLRHTVRDGDATDGANSVGDLVCRFILEGSSLRAVLSRQARNVASPQSDEFGWTILSALVDDIVWRVDGPTVHVEILKRRTGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q713</accession>
    <name>C7Q713_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7197"/>
    <dbReference type="EnsemblBacteria" id="ACU76026">
        <property type="protein sequence ID" value="ACU76026"/>
        <property type="gene ID" value="Caci_7197"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7197"/>
    <dbReference type="eggNOG" id="COG0702">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OMA" id="FLMPGYG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="285" mass="29223" checksum="A4E7E700F84EBB75" modified="2009-10-13" version="1">MSGLTVVTGATGNVGGSLVTALVAAGMPVRAVVRSEADAARFDSGAVQTAIGDLNEPASLAAALDGAQALFLLPGYADMPGVYAAAREAGVGHVVQLSGMSAASGDMSNAVTEYMVLSEQAAAESKLPHTVVRPSAFMTNALRWADQVRAGDTVTLPFPTVATACLHPADLGAVIAAVFADPDRYAGEVLLPTGPEALLPRDQVAIVAGVLDRPLTFVGLTDEQARESMAADGTPQRYIDAFLDFYAKGSLDESPVRSTVADVTGNAPRTFAAWAADNAEAFARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q735</accession>
    <name>C7Q735_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795776.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7219"/>
    <dbReference type="EnsemblBacteria" id="ACU76048">
        <property type="protein sequence ID" value="ACU76048"/>
        <property type="gene ID" value="Caci_7219"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7219"/>
    <dbReference type="eggNOG" id="COG4269">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_155816_0_0_11"/>
    <dbReference type="OMA" id="WIKWFLL"/>
    <dbReference type="OrthoDB" id="1945355at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010295">
        <property type="entry name" value="DUF898"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05987">
        <property type="entry name" value="DUF898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="114" mass="13095" checksum="000D5CAC862FCCE1" modified="2009-10-13" version="1">MAREGESFRFDGGAATFWGTALLAGFITVFTLGVCYPFGVVLMQRWQAKHSFIDGRRLVFTGSAWGLFGNWIKWWFFCLITLGIYGFWVIPRLTQWKWQNTAFDPAAQPAPYVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7E5</accession>
    <name>C7Q7E5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1308"/>
    <dbReference type="EnsemblBacteria" id="ACU70233">
        <property type="protein sequence ID" value="ACU70233"/>
        <property type="gene ID" value="Caci_1308"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1308"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_2_2_11"/>
    <dbReference type="OMA" id="SRHATRM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="18048" checksum="4C6A7186FFF4DACC" modified="2009-10-13" version="1">MTATEPRWLDDEEMRAWLAYRRMRLLLSAAINRDLAQEAGLSEADYDVLSNLTASDDRRRLSELATRMQWSKSRLSHHITRMEQRGLVRREEVDGDARGSLVVLTPHGRRTIERAAPGHVASVRRHLIDRLSEEQIRVLGEIGELVLDPLEAEGSVADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7R2</accession>
    <name>C7Q7R2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787548.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3348"/>
    <dbReference type="EnsemblBacteria" id="ACU72255">
        <property type="protein sequence ID" value="ACU72255"/>
        <property type="gene ID" value="Caci_3348"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3348"/>
    <dbReference type="eggNOG" id="ENOG50343BG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1420693_0_0_11"/>
    <dbReference type="OMA" id="NGEQMAP"/>
    <dbReference type="OrthoDB" id="1645460at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982999" evidence="2">
        <location>
            <begin position="40"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="19581" checksum="1346A03E88975D41" modified="2009-10-13" version="1" precursor="true">MAMQRSGPSFGRTLAAGVAVAALMAVSACGGGSSKPSSATSNTTTATTATTAPSTTASPSTSPSSSESSSPATSGASAPADPAAAEAQIKQNWQLFFDPKTAVADKEKYLQNGAVLAPLLQAFAADPRVGQVSSTVSSVSFTSPTTATVTYSLSLQGTVVEPNATGKAVLQDGTWKVADTTLCGLVALTGNTKLPGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7X0</accession>
    <name>C7Q7X0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhamnose ABC transporter, periplasmic rhamnose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5278"/>
    <dbReference type="EnsemblBacteria" id="ACU74137">
        <property type="protein sequence ID" value="ACU74137"/>
        <property type="gene ID" value="Caci_5278"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5278"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_0_11"/>
    <dbReference type="OMA" id="KQVNNPY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015762">
        <property type="term" value="P:rhamnose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013459">
        <property type="entry name" value="RhaS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02637">
        <property type="entry name" value="RhaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982617" evidence="2">
        <location>
            <begin position="39"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="3">
        <location>
            <begin position="72"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="373" mass="38554" checksum="A7E5C66C5280885E" modified="2009-10-13" version="1" precursor="true">MSTVLRRGAPRSRRRRPRVAVALAASGLLALSLSACGGATKSSTDKAASSAPAAGQSGSANPSAAVKKGLTVAFLPKQVNNPYFNISDAGGNTALTALGESYKEVGTTSATDTAGQVSYVNTLTQQHVSAIAVSAQDPGALCTALKQAMSAGIKVVTYDSDTDPGCRQAFVSQASSEALGRSEVDLLGKELNYTGQIAILSAAQTATNQNAWIGYMQDELKKPQFANMKLVKIAYGNDDAQMSFQQTQGLLQQYPDLKGIISPTTVGIKAAAQYLDGSQYKGKVLLTGLGTPNDMRSYVQDGTVKAFELWDPGKLGQLAAYAAVALASGQISGAQGQSFTAGPMGNFTLGAQGVITLGAPTVFDASNIGQFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z2</accession>
    <name>C7Q7Z2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5300"/>
    <dbReference type="EnsemblBacteria" id="ACU74159">
        <property type="protein sequence ID" value="ACU74159"/>
        <property type="gene ID" value="Caci_5300"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5300"/>
    <dbReference type="eggNOG" id="ENOG50333YK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125494_1_0_11"/>
    <dbReference type="OMA" id="IAELTFD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="15837" checksum="3B1140502BA223FD" modified="2009-10-13" version="1">MPKLTNGASAEDIGLLSALGGMFDEIDPVPPEVVTAGYAAFTWRTIDAELAELAEDSMLAGAGSTRGSDTRLLTFEAPSVSVVVEVTEIGDRRKLVGQLIPACSDTLRIEHPAGATTVTVDGQGLFSADSLPAGPARVALTVPGGGAVVTSWVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q816</accession>
    <name>C7Q816_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793912.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5324"/>
    <dbReference type="EnsemblBacteria" id="ACU74183">
        <property type="protein sequence ID" value="ACU74183"/>
        <property type="gene ID" value="Caci_5324"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5324"/>
    <dbReference type="eggNOG" id="COG0582">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_911905_0_0_11"/>
    <dbReference type="OMA" id="LNTEMAG"/>
    <dbReference type="OrthoDB" id="1795504at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="154"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="36511" checksum="B93D9FE510E95682" modified="2009-10-13" version="1">MPQKAKPAGAEGASIEAWTERVITEREVSKARARQLRWVAGELALVRNHEEFPFRDASSAADLLQPGAISAYLDLAARGELRRRAKAGDARATNASMRIRADCLKILGEHAGVLVAVADRPGLPELRETVDGPSRSQLRDFLASRAEHVGAPAARVRLFALIGVELDTGARVGELAALTLADLADDLSTLRIVRRPQARTVSEAVHDTVKLSDGSRAALRAWLEVRETLVEPLHGNAKALWVSVMPNHAGRLNVEGEAIRRPPGMPLMPRGMQRAYTRAVVEANMNLAGSPGWIPLPVRFEQLRRAVTERQRRDQDQDHQTGDTDRTDTTDIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q860</accession>
    <name>C7Q860_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793956.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5368"/>
    <dbReference type="EnsemblBacteria" id="ACU74227">
        <property type="protein sequence ID" value="ACU74227"/>
        <property type="gene ID" value="Caci_5368"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5368"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015278_2_0_11"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983007" evidence="1">
        <location>
            <begin position="26"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="236"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="589" mass="61951" checksum="362A8A2D5A57B982" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8I8</accession>
    <name>C7Q8I8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7349</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795904.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7349"/>
    <dbReference type="CAZy" id="GH4">
        <property type="family name" value="Glycoside Hydrolase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76176">
        <property type="protein sequence ID" value="ACU76176"/>
        <property type="gene ID" value="Caci_7349"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7349"/>
    <dbReference type="eggNOG" id="COG1486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045951_0_1_11"/>
    <dbReference type="OMA" id="NEHASHI"/>
    <dbReference type="OrthoDB" id="277080at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001088">
        <property type="entry name" value="Glyco_hydro_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022616">
        <property type="entry name" value="Glyco_hydro_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32092">
        <property type="entry name" value="PTHR32092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02056">
        <property type="entry name" value="Glyco_hydro_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11975">
        <property type="entry name" value="Glyco_hydro_4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00732">
        <property type="entry name" value="GLHYDRLASE4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_4C" evidence="7">
        <location>
            <begin position="190"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="45516" checksum="10C4C338C7CB638E" modified="2009-10-13" version="1">MKLAVVGGGSTYTPELVDGFARLRDTLPLTELALIDPAADRVELIGGLARRIFAKQGHPGTVTTHTELESGIEGADAVLIQLRVGGQTIRNVDETFPLEFCCVGQETTGAGGFAKALRTVPVVLDIAERVRRIAPQAWIIDFTNPVGIVTRALLDAGHRAVGLCNVAIGFQRRAAAHLGVQPSRIKLDHVGLNHLTWERGFYLDGEDFLPKYLSESLEEISHDIELPAELIQRLAAIPSYYLRYFYAHDIVVKEQIDQVAKGENRAKAVAAVEAELLAQYADPTLDTKPEALSKRGGAFYSEAAVELLASLHGDLGEELVVNVRNAGTFPFLADDAVIEVPAIVDASGVRPAPLRAPIEPLYRGLIGHVSAYEELAVEAAIKGGVERVRTALLAHPLIGQADLADKLADSLVAKNRSFLPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8J2</accession>
    <name>C7Q8J2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785551.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1334"/>
    <dbReference type="EnsemblBacteria" id="ACU70257">
        <property type="protein sequence ID" value="ACU70257"/>
        <property type="gene ID" value="Caci_1334"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1334"/>
    <dbReference type="eggNOG" id="ENOG5032ZHB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117657_0_0_11"/>
    <dbReference type="OMA" id="CTIRLIV"/>
    <dbReference type="OrthoDB" id="1946162at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025361">
        <property type="entry name" value="DUF4265"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14085">
        <property type="entry name" value="DUF4265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="162" mass="17913" checksum="796B158256BDFD82" modified="2009-10-13" version="1">MTAISDDQVKLHFRMEVDEAGWPPASVESLWAVDLGDGTVRLANTPWFVRGVASGDVIRVRVDEEGVRWAGKVVQASDNCTIRLIVLKDGGSAEARQTVLETFHRLGTTGEGIEQFRMVALRVPPSADLARIRKLLHHGETKGWWHWEEGCVTAAWTAADPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M1</accession>
    <name>C7Q8M1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785580.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1363"/>
    <dbReference type="EnsemblBacteria" id="ACU70286">
        <property type="protein sequence ID" value="ACU70286"/>
        <property type="gene ID" value="Caci_1363"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1363"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1118586_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980695" evidence="1">
        <location>
            <begin position="36"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="248" mass="25335" checksum="72F4C959D1DB43D4" modified="2009-10-13" version="1" precursor="true">MSSEPTPTRRPIAAVRISTIALLGIVAAVAVPACAAAIVLSGTVDSKQVQQNLGMDQPVSRVVIVDSDSSVHVTANPALFGVSGQATLSWHAFSGTSHAKVVEQYADGVLTLSKDCGGIDCGADIDIQVPPKVSVQVNTSNAGISVTGVLGAVDLHSSNASITAKQLGSGDATLATQNASIHASFTGAPKSIRATTSNASVSIVTDGHTPYYDDVKTSNGDTNLQNVRDRRSANVLYIHTSSGGITVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8M2</accession>
    <name>C7Q8M2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785581.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1364"/>
    <dbReference type="EnsemblBacteria" id="ACU70287">
        <property type="protein sequence ID" value="ACU70287"/>
        <property type="gene ID" value="Caci_1364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1364"/>
    <dbReference type="eggNOG" id="COG3595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1118586_0_0_11"/>
    <dbReference type="OMA" id="RIEMNGV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="3">
        <location>
            <begin position="135"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="248" mass="24638" checksum="78C90918AE4BD76A" modified="2009-10-13" version="1" precursor="true">MTSNATPNRAPIGALRMSTIAVAGVIVAVGVPAVAAAIALSTQVSDQQALVKIDAAGPISRIVIADSDSDVRITGDAAANGVTGQAVVQWKGEDGKRPALRQSVSGGVLTLIKDCSGGGCGPIDIMVSVPRDVSVQATTSDGNIALSGVTGQVDLTSSAGSIDADGLGSANASFHTTNGTIDAAFTGAPARIVAETTNASVAIGTDGRTAYYDAVHTTDGVESLTNAQDRTSPDEIDATTTNGDVTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W3</accession>
    <name>C7Q8W3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785672.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1455"/>
    <dbReference type="EnsemblBacteria" id="ACU70378">
        <property type="protein sequence ID" value="ACU70378"/>
        <property type="gene ID" value="Caci_1455"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1455"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_92_2_11"/>
    <dbReference type="OMA" id="LMDDPMR"/>
    <dbReference type="OrthoDB" id="551294at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="17"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="268"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="512"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="548" mass="57374" checksum="7612B2A1DBAEE5B2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8X3</accession>
    <name>C7Q8X3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787586.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3387"/>
    <dbReference type="EnsemblBacteria" id="ACU72293">
        <property type="protein sequence ID" value="ACU72293"/>
        <property type="gene ID" value="Caci_3387"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3387"/>
    <dbReference type="HOGENOM" id="CLU_2841734_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980702" evidence="2">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="65" mass="6195" checksum="69F7170C3CA2B0B1" modified="2009-10-13" version="1" precursor="true">MARSRTAAGLAVLASALTVGLTPAVLITAAVPHSSRTVAAGSPQGIEGTGKSGIVVPDGIQGTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9V6</accession>
    <name>C7Q9V6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7450"/>
    <dbReference type="EnsemblBacteria" id="ACU76275">
        <property type="protein sequence ID" value="ACU76275"/>
        <property type="gene ID" value="Caci_7450"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7450"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_3_11"/>
    <dbReference type="OMA" id="ELYHTNT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="317" mass="34662" checksum="38747C609DCDD560" modified="2009-10-13" version="1">MLDTASEPTADPTGRAGRNGPHIPRIRASRRRPASEDTRIWNRLALPGTLWMSLFFISSLLLLAALSFGTTDDLGNPHFGRTLDNIRRLAAPAYRTVMLRSLEYAALTSLLCLLIAYPVAYAIALHAGRFKNALIAAIVVPFFANYLVRMYGWSVVLSDDGPVLRFLRAIGLADSHTKILNTGPGVIAGLVYGFVVFMVIPLYAALERLDISLIEAGRDLYGGPLRTFLFVTVPATRQGAVAGMVLVFLPAMGDFVSAQFLGGPNQIMIGNLIQDKFFEGQDWPLGSALTMLLMAVLLIGMFGYLRRARKDEAEATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9W3</accession>
    <name>C7Q9W3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796007.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7457"/>
    <dbReference type="EnsemblBacteria" id="ACU76282">
        <property type="protein sequence ID" value="ACU76282"/>
        <property type="gene ID" value="Caci_7457"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7457"/>
    <dbReference type="eggNOG" id="ENOG50339GA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754921_0_0_11"/>
    <dbReference type="OMA" id="RAYWKEH"/>
    <dbReference type="OrthoDB" id="1887386at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="150" mass="16951" checksum="1E67180CD34D370C" modified="2009-10-13" version="1">MAGISDEAVRAYWKEHREQLRQCETQRSALTNLLIVITAALSALIAQQHFSLYVIPLCIFIMLAGLYGAVAVSKYYERAAYHLSQARALTQDLVELGILGSDQRLVQARADHYRAFPWLHRIRLHSLWVILHVAIMFYGLSLLAVCVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X8</accession>
    <name>C7Q9X8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796022.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7472"/>
    <dbReference type="EnsemblBacteria" id="ACU76297">
        <property type="protein sequence ID" value="ACU76297"/>
        <property type="gene ID" value="Caci_7472"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7472"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_3_11"/>
    <dbReference type="OMA" id="ALVYWRP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="24793" checksum="7F37C1CF095EE378" modified="2009-10-13" version="1">MTQHSQVTEPGHAPGRKRDASRDDALCQAALEVLADVGYDRLTIDAVAARAGAGKATCYRRWAGKAELVVDAVGRMKAQPELPDTGTLRGDLVELTCHFHEGDDAFRTDVQAGLVSGLVRDAKLREVFAEHFIAPRKEVFRVVFDRAVARGEIAPVADYDLLSDVVPSMVFHQMMLTGRAPGPAFVHKVLDQIILPLTTPNTNTNTNTNPHSHSHSHHSATQTRTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA55</accession>
    <name>C7QA55_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ordered locus">Caci_1532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785747.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1532"/>
    <dbReference type="EnsemblBacteria" id="ACU70453">
        <property type="protein sequence ID" value="ACU70453"/>
        <property type="gene ID" value="Caci_1532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1532"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_11"/>
    <dbReference type="OMA" id="FNPMNNG"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="21"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20711" checksum="2DDBE7B693FEE31B" modified="2009-10-13" version="1">MIDETLLEAEEKMDKAVEVAKEDLSGVRTGRANPAMFSKLTADYYGSPTPLSQMASFQVQDARMVVIAPYDKTALGAIERSIRDSDLGVNPSSDGVVIRVVFPQLTEERRKEYIKVAKTKGEDAKISVRNIRRHSKESLDKLAKDGDAGEDDVRRAEKHLDELTQKHTAQIDEMLKHKEAELLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAD9</accession>
    <name>C7QAD9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3533"/>
    <dbReference type="EnsemblBacteria" id="ACU72438">
        <property type="protein sequence ID" value="ACU72438"/>
        <property type="gene ID" value="Caci_3533"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3533"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033716_1_0_11"/>
    <dbReference type="OMA" id="PDFRAWT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002397">
        <property type="entry name" value="Cyt_P450_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00359">
        <property type="entry name" value="BP450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="45063" checksum="EC1878191ED8EB25" modified="2009-10-13" version="1">MTVKDADIARALMPVLGADHATVAERLHGEPGGVHCARLAGGERVWVVSRYDDVRTLLADPRLALNKKASLAGYEGFGLPPALEANLLNLDGGDHARLRRLVASAFTARRVEGLRERIQAQVDAFVDALAAEGQDADTEAETEADVDADADADVTDLVAAYAAPVPIAVVCDLLGVPGEQGVTLRGYTQVLLAPGEYGPSDLAATMRGIIGLLSGLLAAKRDDPADDLLSAMIAARDGEDRLSEDELLSLAFLILFAGYENSVHVISAAVARLLTDPAAAAAVRAEPNPHTPGMAALTEEILRRDQPGTTAIRRPTEDVALGDGVVIPAGDTVLLSVSSANRDPKATATATASANATPGHVTFGHGVHYCLGAPLARLEVSIALWTLLTRLPDLALAVPSEDLVWRSSHRQRSLAALPVTVGKALPPAAHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAN5</accession>
    <name>C7QAN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5499"/>
    <dbReference type="EnsemblBacteria" id="ACU74358">
        <property type="protein sequence ID" value="ACU74358"/>
        <property type="gene ID" value="Caci_5499"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5499"/>
    <dbReference type="eggNOG" id="COG4924">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035709_0_0_11"/>
    <dbReference type="OMA" id="PPLICAE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013495">
        <property type="entry name" value="CHP02679"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024466">
        <property type="entry name" value="CHP02679_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024465">
        <property type="entry name" value="DUF2399"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09664">
        <property type="entry name" value="DUF2399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11796">
        <property type="entry name" value="DUF3323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02679">
        <property type="entry name" value="TIGR02679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3323" evidence="2">
        <location>
            <begin position="30"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2399" evidence="1">
        <location>
            <begin position="263"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="408" mass="44543" checksum="755F5754AFC61706" modified="2009-10-13" version="1">MTGLDRYHNPEYRRLWKAARGSLERSGGVLTGSVSIVSPSEDERAAVIGLTRSHRSANSARVTVRMTELDEAVRRTTRLSLAEALTILGGPLRNKPAERDTDLAAREAVLAKMRSSPLHDQHEWFSQWAAELESGGALAKAIRQNGTHRILDAVRVLEHIEERAGTATIVLLPELADKITSDTKALNRGTPTATLVLKALARRAQLPLPTDAEGIRELWESADVVVDDLASRVLVLNLPAAGPGLGEWLTGAAAYGTPFQVTLNQLSRHLVRTDVVEVFVCENPAVLRRASEALGPKSRPLICTEGRPSAAFHRLAQIIRDGGGRLRYHGDFDWPGVSIARQVIERHQAAAWHFGASDYRMAVDGGERLPLKGAAQPTPWDDRLSLAMQSLGCAVYEESVSDVLLRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAP2</accession>
    <name>C7QAP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5506"/>
    <dbReference type="EnsemblBacteria" id="ACU74365">
        <property type="protein sequence ID" value="ACU74365"/>
        <property type="gene ID" value="Caci_5506"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5506"/>
    <dbReference type="eggNOG" id="COG0420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026621_4_0_11"/>
    <dbReference type="OMA" id="FVYAMKW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="10"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="425" mass="46583" checksum="CF41C2D234B4DAB5" modified="2009-10-13" version="1">MLNRLGVPPLKLLHAADLHIDSPLHGLEKYPDAPVDMIRAASRRATENLVALALDEQVDAVLLAGDVYDGDWRGYDTGLFFQRQLGILGDAGIQVYLVSGNHDAQSQITKNLRLPNNVHKFDTHQSQSIEDPDVGLVVHGQGYARRDVMENLAADYPRAMPGMFNVGLLHTALTGRAGHTKYAPCSVEELVSRGYGYWALGHVHTREVVFEEPHIVFPGNIQGRSIRETGPKGCTLVTVTDKGSVAVEHRDLDVVRWAHLRVDATSADDLDDVCELVRTQLATERDRSDGRLVAARVTVTGRSAAHAELWRERERLTVEVRSIAVDLGEVWVEKVGPGTSPLDAGAGDGVNDVTDMIAGLLRTAKELGTDEDAVRRFVERDPLWSKLSGDVRGEDRLNSSSAEWCAQLLSEASDLLVSMLQEGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBC7</accession>
    <name>C7QBC7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_7594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7594"/>
    <dbReference type="EnsemblBacteria" id="ACU76418">
        <property type="protein sequence ID" value="ACU76418"/>
        <property type="gene ID" value="Caci_7594"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7594"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="OMA" id="NIHGEGF"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU76418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="228" mass="25281" checksum="163C26888E3F0F9B" modified="2009-10-13" version="1">MVRMKGRVLIVDDDIALSEMLGIALRGEGFETTSVADGDRALQVFRDFKPDLVLLDLMLPGRDGIDVCRLIRGESGVPIIMLTAKSDTVDVVVGLESGADDYVIKPFKVKELVARVRARLRRADEPKPETLAIGDLSIDVAGHSVKREGRQIPLTPLEFDLLVALARKPWQVFTREVLLEQVWGYRHAADTRLVNVHVQRLRSKIEVDPENPEIVVTVRGVGYKAGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBK3</accession>
    <name>C7QBK3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ordered locus">Caci_1659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1659"/>
    <dbReference type="EnsemblBacteria" id="ACU70580">
        <property type="protein sequence ID" value="ACU70580"/>
        <property type="gene ID" value="Caci_1659"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1659"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_0_1_11"/>
    <dbReference type="OMA" id="LMSPLHH"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="381" mass="39994" checksum="AF25283910503478" modified="2009-10-13" version="1" precursor="true">MSTYSAALAGVGAVVPHAGSEGGLQMRGVLYAAGIALFFSLIGTPMAIKTLARYGFGQPIREDGPTTHQAKRGTPTMGGVVIVLATVLGYGFTKLATMRAPTASGLLVLFLMVGMGLVGFTDDFLKVFRQRNLGLRAKAKMIGQWIVAIVFAVLALHFPNSLGFTPGDTHLSFVRNISAIDLGAVLFVIWAGLLIAGTSNGVNLTDGLDGLATGSCVMVFASYVLIGVWQHGESCATLGTGVQGCYPVRDPLDLAIVAAAIMGACFGFLWWNTSPAKIYMGDTGSLALGGALAGLAICSQTELLLALLGGLFVIITLSVVIQVGYFKISGGKRVFKMAPLHHHFELVGWAEVTVVVRFWIICGLFVGLGLGVFYAGWITVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA7</accession>
    <name>C7QCA7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794284.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5697"/>
    <dbReference type="EnsemblBacteria" id="ACU74555">
        <property type="protein sequence ID" value="ACU74555"/>
        <property type="gene ID" value="Caci_5697"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5697"/>
    <dbReference type="HOGENOM" id="CLU_2506645_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983018" evidence="1">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="85" mass="9255" checksum="5303CF0DC80C1723" modified="2009-10-13" version="1" precursor="true">MRTRRLRRTGVPALVGLTIAGTMTLSTGTASAGAWLSTGYYFPSQASCSNWAGNVAGAYGWTAWDCRYDPSRQDGMHWLLFAFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCT0</accession>
    <name>C7QCT0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7719</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7719"/>
    <dbReference type="EnsemblBacteria" id="ACU76543">
        <property type="protein sequence ID" value="ACU76543"/>
        <property type="gene ID" value="Caci_7719"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7719"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="WIQAWNE"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="30884" checksum="EBEB6C73079DDF2C" modified="2009-10-13" version="1">MSAAYRRAPRRAMTAFWNSVAMLVAIVLGFPIYWMLLTTVKSNKDLISQHPTFWPSHFDFSSFSSAMDDNFGANLWNTVVITLGSVFISLAVGLLAALAVARFDFRGRKPFIVAILVVQMVPLLTILVGLLPLLNSTNLYGSVLGVILAYLVFTIPFIIWTLRTYIVGIPVELDEAAMVDGCTKAQAFRRVVLPLLAPGLVSTGVFAWIQAWNEFVMAREILAPAQNKTAMVWLTFFSDTPTHGSDYSGQMAGALIIAAPVIILFTVFQSRLSTGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCV4</accession>
    <name>C7QCV4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785958.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1743"/>
    <dbReference type="EnsemblBacteria" id="ACU70664">
        <property type="protein sequence ID" value="ACU70664"/>
        <property type="gene ID" value="Caci_1743"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1743"/>
    <dbReference type="eggNOG" id="ENOG50320NN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1052483_0_0_11"/>
    <dbReference type="OrthoDB" id="1412442at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="29220" checksum="D4DB1DF899527B42" modified="2009-10-13" version="1">MITWGSLTFAEQTLMRHAIGGRRLAGSVQVYGIGLRWAGAADAPPLRSYTDAEQRKLIPMLAATVLDLIDGGYLVVQESHHAFLRPSDPILAGSQVRDVLADADNWIWDHERSRHFYLGAPAAVREQWTEDAWPAADATGLPTWNELTETEQDILICAQESSGMLTGDFGDWPDPPADSSPAERLAFVEEQLSPLLPFVRKGWIEVRHMPDATSDAFTVIPFEELHSAFADPAMRYQGEEWGIGLSCVFTYAGLAVRRGGAWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD30</accession>
    <name>C7QD30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extradiol ring-cleavage dioxygenase class III protein subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1819</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1819"/>
    <dbReference type="EnsemblBacteria" id="ACU70740">
        <property type="protein sequence ID" value="ACU70740"/>
        <property type="gene ID" value="Caci_1819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1819"/>
    <dbReference type="eggNOG" id="COG3384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046582_2_1_11"/>
    <dbReference type="OMA" id="RTEHFAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016701">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LigB" evidence="5">
        <location>
            <begin position="35"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="29068" checksum="1138B0E157F3A3F2" modified="2009-10-13" version="1">MTADMNTSTASTASPERMPAIYLSHGAPPLADDPLWPSQLAAWSANLPKPKAILMVSAHWEEAPLALGATTTVPLVYDFWGFPQHYYEVTYRAPGAPALADSVRKMLHAPGLEVQDEPARGLDHGAYVPLVEMYPQADVPVLQVSMPTLEPSQLMAIGRRLAPLRDEGVLIIGSGFFTHNLRALSQDGKVHSVMSEFDDWGHQALAAADVDALLDFENKAPAGKLAHPRTEHFAPLFVTLGAAEAELGTQRSVIDGFWMGLAKRSVQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDB0</accession>
    <name>C7QDB0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792432.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3801"/>
    <dbReference type="EnsemblBacteria" id="ACU72703">
        <property type="protein sequence ID" value="ACU72703"/>
        <property type="gene ID" value="Caci_3801"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3801"/>
    <dbReference type="eggNOG" id="COG2312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1934251_0_0_11"/>
    <dbReference type="OrthoDB" id="1068352at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="13935" checksum="D4E16716FD4C36A4" modified="2009-10-13" version="1">MSITGNVRAERGPQATVGSLLRSRFGTRYASVAIGFHHGDLGVAVVPDPAPDLIDVVLGEAADRPAYWLDLRAAPVGRWDDAAKIRVISGVYDPSRDAAEHMAVTSLTAAFDVLVHIRRASPVRWLPIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDL5</accession>
    <name>C7QDL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794368.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5781"/>
    <dbReference type="EnsemblBacteria" id="ACU74639">
        <property type="protein sequence ID" value="ACU74639"/>
        <property type="gene ID" value="Caci_5781"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5781"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_2_2_11"/>
    <dbReference type="OMA" id="WRRPRWC"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="822"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="895" mass="94216" checksum="F433091DAC8CFB82" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDM9</accession>
    <name>C7QDM9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ordered locus">Caci_5795</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794382.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5795"/>
    <dbReference type="EnsemblBacteria" id="ACU74653">
        <property type="protein sequence ID" value="ACU74653"/>
        <property type="gene ID" value="Caci_5795"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5795"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031507_0_0_11"/>
    <dbReference type="OMA" id="TIINDAW"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="107"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="317"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="447" mass="45465" checksum="14A57B2226BFA4FA" modified="2009-10-13" version="1">MIPLSLEEIAVVVGGTVAGGGSVTVTAPAALDGRKAEPGGLFVAFAGEYADGHDFVDQAARAGAAAVLGTRPTSLPTVVVQDAREALQRLAKHVVDRLRPGLTVVGVTGSQGKTGTKDLIAAVLSSAAPTVATAGSLNNELGVPLTMLRADAETRFLVLEMGARHVGDIAALTDLVAPDVAVVLNVGRAHLGEFGSRGAIAKTKAELVQGLAPGGTAVLNADDPRVAAMHTLTDGPLLTFGRAEHADVQVLYLVLDRLGRPSFTVRTADARAVVTLPLIGAHQSLNAAAAVTAGLAAGVPLEAATKALATASLSKWRMELRGLAGGATLLNDSYNANPDSTRAALDALAAIEAARRIAVLGEMRELGPSTETEHRAIGRYAAHRADIILAVGAPAHPIATAAGPRALTLPDNDAALAWLREHLAAGDVVLVKASRGGRLDEVAAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDP0</accession>
    <name>C7QDP0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5806"/>
    <dbReference type="EnsemblBacteria" id="ACU74664">
        <property type="protein sequence ID" value="ACU74664"/>
        <property type="gene ID" value="Caci_5806"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5806"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045963_0_0_11"/>
    <dbReference type="OMA" id="EFEPMHQ"/>
    <dbReference type="OrthoDB" id="1240965at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="3">
        <location>
            <begin position="41"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="442" mass="46131" checksum="9B8D51117C5821C0" modified="2009-10-13" version="1">MTTVTSPTGPTAPTEPPAPPRTATARVLVRRPKLWLIPAVLATLVALFLSLLYMGGILDPNGNLHHLPIALVDADTGAPPPGQPQNLGAQVAQAVVTGAPTGQFDWKRVDRAEAQDMLASGKVYGAFEIPADFTASVVALTTGQGTVRPTITVLTNPGLGSLGSSIASQVTQNAAHQASLSIGKQLTASPATSAADPTTRLLFADPVAVTTQIGHPIGRHSGLGLSAFYYALLLVLSGFIGGNLIHAGVDTALGYADSEMGPWHTRRPTVPITRTQTLLLKMLMTAGIALLTVSMVIVACIVALGMDATHIPLLWIFSYCACLAIGLGVQAINAAFGGIGQLVSMFVFIALALPSSGATVPLQAAPPLFRFLGTFEPMRQLAGGVRAIIYFDARGDAGLSRAWLMIAVGVVGALVFGFAMTRYYDRKGLRRLTPQPMAPQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDT9</accession>
    <name>C7QDT9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Maltose/maltodextrin transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_5855</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794442.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5855"/>
    <dbReference type="EnsemblBacteria" id="ACU74713">
        <property type="protein sequence ID" value="ACU74713"/>
        <property type="gene ID" value="Caci_5855"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5855"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_20_1_11"/>
    <dbReference type="OMA" id="LLVWRDM"/>
    <dbReference type="OrthoDB" id="1619224at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030156">
        <property type="entry name" value="MalF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035277">
        <property type="entry name" value="MalF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032550">
        <property type="entry name" value="TM_PBP2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47314:SF1">
        <property type="entry name" value="PTHR47314:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16296">
        <property type="entry name" value="TM_PBP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="287"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU74713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="55975" checksum="24BD3B53E3F40D77" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE45</accession>
    <name>C7QE45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7809"/>
    <dbReference type="EnsemblBacteria" id="ACU76633">
        <property type="protein sequence ID" value="ACU76633"/>
        <property type="gene ID" value="Caci_7809"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7809"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_360826_0_0_11"/>
    <dbReference type="OMA" id="GRWPSAP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="641"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="686"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="289"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="425"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="670"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="775" mass="79873" checksum="D3FD66D44D616CB2" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE57</accession>
    <name>C7QE57_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796370.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7821"/>
    <dbReference type="EnsemblBacteria" id="ACU76645">
        <property type="protein sequence ID" value="ACU76645"/>
        <property type="gene ID" value="Caci_7821"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7821"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_23_0_11"/>
    <dbReference type="OMA" id="RGQYESD"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="43"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="290" mass="29866" checksum="2656DD5F68E29059" modified="2009-10-13" version="1">MSTPPFVDLPPFTVAVQLPTAGGPLAALRATPPAGVTRLGAAVLVPGFTGSKEDFIAVMTPLAEAGYEVVSLDQRGQNESAGPEDPSAYTLPQLAADLADVIDGLTDDTSASVHIMGHSFGGLVAREYALSHVGRVRSLALLDSGPAAIPGRSAEQATLLVAAAGFMTSAEIWAEMQKISVAEGAPQHRDPAVRAFLQQRFENNGTAMLAGMGTSILSAVDRTAELAAAGLPLLVAAGVGDDAWPVQLQKEMATQLGTDLVLIEDAAHSPAAENPPATAQLLVDFWARNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QED2</accession>
    <name>C7QED2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_1903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1903"/>
    <dbReference type="EnsemblBacteria" id="ACU70823">
        <property type="protein sequence ID" value="ACU70823"/>
        <property type="gene ID" value="Caci_1903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1903"/>
    <dbReference type="eggNOG" id="COG1141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139698_6_0_11"/>
    <dbReference type="OMA" id="CVMVASE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU70823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="77" mass="7978" checksum="24BAB73CEDDB1E51" modified="2009-10-13" version="1">MVSPDGGVTMRVEADRGKCMGAGMCALNAPEVFDQDEDEGLVVVLESEPAAGHRFAVRDAANLCPASAITLIEEDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEI9</accession>
    <name>C7QEI9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786173.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1960"/>
    <dbReference type="EnsemblBacteria" id="ACU70880">
        <property type="protein sequence ID" value="ACU70880"/>
        <property type="gene ID" value="Caci_1960"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1960"/>
    <dbReference type="eggNOG" id="ENOG502ZEUB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1371287_0_0_11"/>
    <dbReference type="OMA" id="FAIRWKL"/>
    <dbReference type="OrthoDB" id="1930042at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="196" mass="21956" checksum="037B74E509D85C81" modified="2009-10-13" version="1">MRRLPGAAHTAQPWLVHEIAGDFLLEDVWELPAPGGGPDDFAVLVSVFDGGLEKDASLPTRALFWLRFKLGAVMRLDRQSTGLGSRVPSLRDRLPEELREQLRDAAPANQASDFTLLYERGNERAMEIANGTMHGILHLGWVPDGRGGWRGQLAILVKPNGRAGAAYMAFIKPFRHLIVYPALGRAWQRRWRQSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QER4</accession>
    <name>C7QER4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792563.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3953"/>
    <dbReference type="EnsemblBacteria" id="ACU72834">
        <property type="protein sequence ID" value="ACU72834"/>
        <property type="gene ID" value="Caci_3953"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3953"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="YSTHYLP"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="299" mass="32136" checksum="60491E859BC1C0A3" modified="2009-10-13" version="1">MLEASGLHKRFGNQIALAGFDLRIEAGEICGLLGHNGAGKTTFARICAGLEHPDAGGVRIGGLDADCRAAHALVGLAPQEIALYPTATLRENLRFYGQLAGIGRSRLRAEINDITASMMLTKVLDRTVATLSGGQQRRAQAATALLHRPAVLLLDEPTAGADPTTRQALLAVVRDRAAQGAAVCYTTHYLPELEELDATIAVAQTGRIIARGDRRKLLSGLPSLLEIGFAAEPSGALDEQVVDGTLRITTDRPAQTLTRILTSLGDRSEQVERVEIREPTLDDLYRHLTRTATETERVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF45</accession>
    <name>C7QF45_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5945"/>
    <dbReference type="EnsemblBacteria" id="ACU74803">
        <property type="protein sequence ID" value="ACU74803"/>
        <property type="gene ID" value="Caci_5945"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5945"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_11"/>
    <dbReference type="OMA" id="LYCLKER"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="33522" checksum="E6EC9D042F1F4306" modified="2009-10-13" version="1">MTQLNLHRLSIFLTVVETGGFSAAAQKLYMSQPSVSNHVRNLEQSLQTTLIDRSGPRIRPTAEGEVLAEYARRIFLLTEEAVAAIREVSGVQSGRLEVGGTTTVGTYLLPRLLARFRERHQNIECDIVVGNNGQILKRLLDGELGLAIVAGQPAAPQLKTETVLDERLLLVAAPGHPLTHPTPHITAPQLAGERFLLREPGSQTRDLQEAALINWDLDDMPKADMWGPETIKQSVAAGLGISLISEHAIDTEVKDGRLAVLEVDPPLRSRPVVIAYRRDRLLSPAERAFVALARGLRTWPDSEAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF63</accession>
    <name>C7QF63_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794550.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5963"/>
    <dbReference type="EnsemblBacteria" id="ACU74821">
        <property type="protein sequence ID" value="ACU74821"/>
        <property type="gene ID" value="Caci_5963"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5963"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126018_0_0_11"/>
    <dbReference type="OMA" id="CANTRDA"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="17859" checksum="4BC2349BEA99F196" modified="2009-10-13" version="1">MIIDLPEGKEPIGYVWGEMVPGIGPAAAAFSMAVYDRTTLGLREFEAARLRVAQINGCLFCLDWRTERDGTKVEDGFDAAVAEWRTVDGFDERTRLAAEYAERYCLDHHNLDEEFWTRMLAVYSQVEVVELTMCLGSWLAFGRLNHVLGIDAACVLPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFW8</accession>
    <name>C7QFW8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2025"/>
    <dbReference type="EnsemblBacteria" id="ACU70945">
        <property type="protein sequence ID" value="ACU70945"/>
        <property type="gene ID" value="Caci_2025"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2025"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_0_1_11"/>
    <dbReference type="OMA" id="EGRNAIW"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="42"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="208" mass="22363" checksum="3050811FA00BC408" modified="2009-10-13" version="1">MTAVEGRGMWEQYYGKSQSVWGWAPNRFVAEVLGPLPAGRALDLAAGEGRNALWLAGLGWRSTAVDFAENALERGRAQAVEHGLEVEWVLADVLEYQPEPGAYDAVVIAYLHLEADPRTAVLHNAAKALAPGGTLVVVGHDVTNIADGVGGPQNPAILYTPERVTEALERLADVDMKIVRAERVHRQTDRAPQPAIDTLVVAQATQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG58</accession>
    <name>C7QG58_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792632.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4035"/>
    <dbReference type="EnsemblBacteria" id="ACU72903">
        <property type="protein sequence ID" value="ACU72903"/>
        <property type="gene ID" value="Caci_4035"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4035"/>
    <dbReference type="HOGENOM" id="CLU_2732613_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="71" mass="7645" checksum="75FF05B3DC9131E5" modified="2009-10-13" version="1">MSELTPLKIMFQGYLARFNELRKEENRESGMGTVELIVIAGALVLIAIAVTAILKSKATGAANNLNLSPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGI7</accession>
    <name>C7QGI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6010"/>
    <dbReference type="EnsemblBacteria" id="ACU74867">
        <property type="protein sequence ID" value="ACU74867"/>
        <property type="gene ID" value="Caci_6010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6010"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OMA" id="NNALVMR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="24"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="420"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="450" mass="46656" checksum="2B2811FC439A6C16" modified="2009-10-13" version="1">MNVLLRERPRPDRIRDLPSAWRLAILTVCFGAFMGQLDASITTLAYPALRTGFHASLAAVSWVSLSYLLTLTVLLVPTGRLSDAFGRKLFYVYGFGVFTAASAACALAPSLDALIAFRVVQALGAAMLQANSIALISNAAPREKLRQALGIQAAAQALGLGLGPAVGGLLVDTLGWRWIFGVNVPVGVVALVGGVFLLPCTRERNPGIKPDLAPLRLHAVRWGLLGAAGGYLVLFGPLVLVPVIMAARGAGALSSGLVLTTLPVGFALGASFLKCRAGVGLGLAVAALAGLLVLPFEPVVLVPLLGVLGLGLGAYAPANNAQVMAAVAQKESGVVSGLLNTARSLGTSGGVYLVTSAIALANHSSGRGSRYAFAGLLIVCLLTLAVSVRPSPHAVPDELVDKFPSPLGPQIGPLVRGDDQQRVGDLRQLPRQKRQPREVGQVEREAAHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ9</accession>
    <name>C7QGJ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794608.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6022"/>
    <dbReference type="EnsemblBacteria" id="ACU74879">
        <property type="protein sequence ID" value="ACU74879"/>
        <property type="gene ID" value="Caci_6022"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6022"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063235_1_0_11"/>
    <dbReference type="OMA" id="LLEMKFA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="233"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="319" mass="34982" checksum="913DCD57A023D507" modified="2009-10-13" version="1">MRIHFTPDDLLHVRFAEEPAPLLELALALASLHRPAADPVFTRWRREAARELPQRARPLLDLIPPCGRGPQFLDPLVPDVEDALERVAASPGSQIRREMARVAGLGRPLTPWTRRIATRDPQAWHELLTAVHTAYDSILTEPWRRLRAGFHAEVAWRTTRWGRLGLGAALESLMPGSKLDGLTWHLAPQKDIDCHLAGHGLTLYPTAMWSGLPLIATSPDGSKLLVYPALTPLPLLPEPQDTDPLGTLLGRTRAQVLEALAEQRTTGKLAHDLGISAASASQHATALREAGLVATRREGKAAWHECTALGAELLRTGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGV1</accession>
    <name>C7QGV1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796526.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7978"/>
    <dbReference type="EnsemblBacteria" id="ACU76801">
        <property type="protein sequence ID" value="ACU76801"/>
        <property type="gene ID" value="Caci_7978"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7978"/>
    <dbReference type="eggNOG" id="ENOG502Z7KC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059899_0_0_11"/>
    <dbReference type="OMA" id="LTYDMTD"/>
    <dbReference type="OrthoDB" id="359173at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="376" mass="41761" checksum="71250C1691B41F77" modified="2009-10-13" version="1">MSDAHRDLSPLDDFPFHQTSESMAHVATSDRNFYDRYYFNVHHCADDLFMALGVGQYPNLGVTDAFAAVVHNGVHRVVRASRELGSDRGDTSVGPFGIEVLEPLNRLRVVLEPGEYELSFDLTWTGSIPATREPRQFVRRNGRVWMDSVRLAQTGYWEGTLRIGEDELTVTPATWWGSRDRSWGIRPVGEAEPAGIGGKDGVPPTFHWIYAPMQFDDFSILVIAQEDEDGGRVLEEAVKVFRDGRPAEALGRPELELHYTPGTRDVETAAVHFTGRAERVRVTQLIPLHMAVGSGYGLDADWRHGMYQGPDLVVQQVVMPAAEAAAKSGMFGITERLARFEYDGPEGVRTGFGLFETLFIGAHRPSGFADWLAVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH31</accession>
    <name>C7QH31_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796606.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8058"/>
    <dbReference type="EnsemblBacteria" id="ACU76881">
        <property type="protein sequence ID" value="ACU76881"/>
        <property type="gene ID" value="Caci_8058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8058"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_5_11"/>
    <dbReference type="OMA" id="ITHRNIW"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="19"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="417"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="514" mass="56149" checksum="83AC520516F64C54" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH58</accession>
    <name>C7QH58_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796633.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8085"/>
    <dbReference type="EnsemblBacteria" id="ACU76908">
        <property type="protein sequence ID" value="ACU76908"/>
        <property type="gene ID" value="Caci_8085"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8085"/>
    <dbReference type="eggNOG" id="ENOG503375I">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133158_0_0_11"/>
    <dbReference type="OMA" id="MTYFPDL"/>
    <dbReference type="OrthoDB" id="2061619at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="15650" checksum="DE590101CF62376C" modified="2009-10-13" version="1">MTYFPDLAPYDYLPETVPHGVELLTVGWLEPGHDFETEAEPLAAAFWPNLITLAADHPVAVTRSVHGCRFRHLFEADYQYRAVYGTRVLYLGSAEIRVVAADGRWLTAPTLVVHYVRDHGYRPPPEFVEAVAAMRVAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHC2</accession>
    <name>C7QHC2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784356.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0106"/>
    <dbReference type="EnsemblBacteria" id="ACU69061">
        <property type="protein sequence ID" value="ACU69061"/>
        <property type="gene ID" value="Caci_0106"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0106"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_7_2_11"/>
    <dbReference type="OMA" id="WGVAANR"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24736" checksum="D5258862EE359F61" modified="2009-10-13" version="1">MDIYEALYTTRAMRRVKPDPIPESVQARILDAAIRAPSGGNGQNWRFLLLDDPEKKKLLGPLYRDALDQLYTTVYAPMLAAIAADPDSPESRQMAKVTKSSRWLGENFEQVPLFLFAFVQRDRSGGSIFPAVWNAQLAARAQGVGSALTSILGGFHDQEVKEILGVPAEEKWTQSCCVSFGYPTGRWGVAPRRPAHEVAYRNGWGEPVGFTVDEPLWQPSPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI19</accession>
    <name>C7QI19_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative lantibiotic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792793.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4200"/>
    <dbReference type="EnsemblBacteria" id="ACU73064">
        <property type="protein sequence ID" value="ACU73064"/>
        <property type="gene ID" value="Caci_4200"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4200"/>
    <dbReference type="HOGENOM" id="CLU_2615523_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023895">
        <property type="entry name" value="Thiopep_bacteriocin_prcur"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03892">
        <property type="entry name" value="thiopep_precurs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="78" mass="7796" checksum="843E1A5002FE83B9" modified="2009-10-13" version="1">METFDTPTSGTLVSLAMELTALDSETFEIQDYAEYDGLMGAAGKAPVGGVQGGGDGNHATSTSSTSTCSTCSTTSCCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII8</accession>
    <name>C7QII8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794794.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6211"/>
    <dbReference type="EnsemblBacteria" id="ACU75065">
        <property type="protein sequence ID" value="ACU75065"/>
        <property type="gene ID" value="Caci_6211"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6211"/>
    <dbReference type="eggNOG" id="ENOG5032YPX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_188872_0_0_11"/>
    <dbReference type="OMA" id="RKFIDCR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009409">
        <property type="entry name" value="DUF1059"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06348">
        <property type="entry name" value="DUF1059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="65" mass="7261" checksum="FD88710FE3F417B0" modified="2009-10-13" version="1">MTRKVADCRQFPSEMNCTLTISGEEQEVVDAAVMHAVAVHGETDTPEFREQLKTFLADEKVPVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ8</accession>
    <name>C7QIJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794804.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6221"/>
    <dbReference type="EnsemblBacteria" id="ACU75075">
        <property type="protein sequence ID" value="ACU75075"/>
        <property type="gene ID" value="Caci_6221"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6221"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OMA" id="HGRHALN"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30458" checksum="3E7E53F1C2976CCF" modified="2009-10-13" version="1">MNDLETRELEYFLAVADELHFGRAAVRLSIAQPALSKAIRRIENRLGVALFVRSSRHVELTGAGKALQEHGRHALNAISAAVRHAQSAGGAQTHLRLVLKPGGDGGLLSGMLAAYAEQPDARYVDILFSGPIDRAEFLLDGRADVGLLYAPFDPLDGLAHEILYTEDRVAVLPAEHRLAGRASVRLTELEGEKRPVWKGAGKDSDTEGSAAIADVVQMLHMITVSRVVEVLPRSLVPALPAGVVLVPVADAPPSHLVLAWNEHDRRPLVASFVEAVLRMAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIM7</accession>
    <name>C7QIM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76927">
        <property type="protein sequence ID" value="ACU76927"/>
        <property type="gene ID" value="Caci_8104"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8104"/>
    <dbReference type="HOGENOM" id="CLU_1988620_0_0_11"/>
    <dbReference type="OrthoDB" id="1929648at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="125" mass="13099" checksum="FD99518CC374E0E9" modified="2009-10-13" version="1">MSLLEAFEPVAHDLRAAGLDCQLTEDPNPGEPAAGATAVLIVSGVKVGRLTLGASVLDTASRTLYLAAQTQRLVQGNLSIGGRVIEWPPCLPSHTHPMMATRGQRTPLWTCPLGGTISVPIGEHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ30</accession>
    <name>C7QJ30_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cell wall binding repeat 2-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0217"/>
    <dbReference type="EnsemblBacteria" id="ACU69172">
        <property type="protein sequence ID" value="ACU69172"/>
        <property type="gene ID" value="Caci_0217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0217"/>
    <dbReference type="eggNOG" id="COG2247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_403197_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982936" evidence="1">
        <location>
            <begin position="46"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="278"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="684" mass="69343" checksum="545A2EDDF7E0D1AB" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG7</accession>
    <name>C7QJG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786483.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2272"/>
    <dbReference type="EnsemblBacteria" id="ACU71190">
        <property type="protein sequence ID" value="ACU71190"/>
        <property type="gene ID" value="Caci_2272"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2272"/>
    <dbReference type="eggNOG" id="ENOG5032ZDA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161414_1_1_11"/>
    <dbReference type="OMA" id="IMRRPER"/>
    <dbReference type="OrthoDB" id="2057624at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045745">
        <property type="entry name" value="HTH_58_Actinobacteria-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19575">
        <property type="entry name" value="HTH_58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_58" evidence="1">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="72" mass="7601" checksum="ECE3DFD9A19A5875" modified="2009-10-13" version="1">MAETLKKGSRVTGDARSQLATDLKAKYEAGESIRALAQSTGRSYGFVHRMLSESGVTLRGRGGATRGKAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJN3</accession>
    <name>C7QJN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hedgehog/intein hint domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786549.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2338"/>
    <dbReference type="EnsemblBacteria" id="ACU71256">
        <property type="protein sequence ID" value="ACU71256"/>
        <property type="gene ID" value="Caci_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2338"/>
    <dbReference type="eggNOG" id="COG4372">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_336722_0_0_11"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982951" evidence="2">
        <location>
            <begin position="36"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="3">
        <location>
            <begin position="668"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="846" mass="86618" checksum="7DECB57A8D006FEB" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJQ5</accession>
    <name>C7QJQ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792872.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4279"/>
    <dbReference type="EnsemblBacteria" id="ACU73143">
        <property type="protein sequence ID" value="ACU73143"/>
        <property type="gene ID" value="Caci_4279"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4279"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_4_11"/>
    <dbReference type="OMA" id="INIEHIF"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="40462" checksum="C4E7D8CDF0E82E6E" modified="2009-10-13" version="1">MRWGAGSISGDMTRTAVLALLARRGPLSRAQIAEMLELSPATITQGTRRLLAEGLLVEEAPRPSAGGGGRPSVPLSLVPGSAHTIGIQVAHEHVTGVTSRLDATVVHSFRHAFDPASPDAVETLTALIRSEIEEIERRGLPLAGVGVAVPGIVEPETGTLSMSVRLGWTGLPLAARLREALGVPVFVDNDISAVTAAERLYGPGADEADFLLAAIGQGIGLGMVLDGAPYRGAAGAAGEFGHMPVQPDGPQCVCGNRGCLESLVSTEALLRTAHEAGILPAESDLDDLGTAARHGDPAAVQLLHNAATLLGRALAGVVNLLGPRSVIIIGEITAIWDLLDDPLHEALLDHLLPAVRDTRIEVRPWHDEVIAASAARVVLAAPLAAPRQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX6</accession>
    <name>C7QJX6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73214">
        <property type="protein sequence ID" value="ACU73214"/>
        <property type="gene ID" value="Caci_4350"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4350"/>
    <dbReference type="HOGENOM" id="CLU_3231295_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="43" mass="4378" checksum="71BEE79B7A845547" modified="2009-10-13" version="1">MASQKRPAKQSVDVSIVSAKEIVLIVLVMVVLAGTAASLALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKM8</accession>
    <name>C7QKM8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796852.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8304"/>
    <dbReference type="EnsemblBacteria" id="ACU77127">
        <property type="protein sequence ID" value="ACU77127"/>
        <property type="gene ID" value="Caci_8304"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8304"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3899">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006850_0_2_11"/>
    <dbReference type="OMA" id="YHAHDPA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1084" mass="116443" checksum="F965607DECDD46C5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKN4</accession>
    <name>C7QKN4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796858.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8310"/>
    <dbReference type="EnsemblBacteria" id="ACU77133">
        <property type="protein sequence ID" value="ACU77133"/>
        <property type="gene ID" value="Caci_8310"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8310"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="HEVLAFC"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="230"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="277" mass="29623" checksum="587376B2D9694DEE" modified="2009-10-13" version="1">MTRLDVREVTVRFGGVTAVDKATISADGGQVTALIGPNGAGKTTLFNVITGLQKPTGGKVFLDGDDITHTPTHRRARHGIARTFQRLEAFGSLTVEENIRVAADAVRAKNTKPAQVTRGLIQRIGLERYAGARADSVPTGVARLVELARALAIDPELLLLDEPSSGLSEAETESFGELLRDLAAQGRAVLIVEHDMGLIMRVSDVIHVLDRGRLIASGTPAEVQADPLVRKAYLGEEDPDESEEPAETEEPTESEEPADSTLVMPAADDEPESGGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKR1</accession>
    <name>C7QKR1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796885.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8337"/>
    <dbReference type="EnsemblBacteria" id="ACU77160">
        <property type="protein sequence ID" value="ACU77160"/>
        <property type="gene ID" value="Caci_8337"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8337"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_0_2_11"/>
    <dbReference type="OMA" id="MQLLGAC"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="34368" checksum="3E1D4789C5B31549" modified="2009-10-13" version="1">MAGAGRTRADGKPSGGRRVLVIGADSRLGRSVVEALREQGRVRFVAGADGADASGSPAIARLIADTDPDTVVHLGLEPRPSRAGGRAAMKERNVIGTMQLLAAASRAPGLKRLVVKSSGAVYGCAPRDPALFAEDTPPHLPPTSGYGKDVAEAEGYVRGFARRRPDVAVSVLRFAPFAGPGVASPLLDYLTLPLVPTVLGFDPRLQFVHIDDAVRALVLAALGGHPGIYNVAGDGAMPLSQITRRLGRPTLPVLSFGAGFFGSLIRRAGIVDFTPDQVAMVRYGRVLDTARVKERLGWEAGYTTADALRAHAEAAGLKPVAPGWTKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVE4</accession>
    <name>C7PVE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol 1-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784595.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0347"/>
    <dbReference type="EnsemblBacteria" id="ACU69300">
        <property type="protein sequence ID" value="ACU69300"/>
        <property type="gene ID" value="Caci_0347"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0347"/>
    <dbReference type="eggNOG" id="COG1260">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050011_0_0_11"/>
    <dbReference type="OMA" id="GTKEWAD"/>
    <dbReference type="OrthoDB" id="669352at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017815">
        <property type="entry name" value="Myo-inos-1-P_Synthase_actino"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03450">
        <property type="entry name" value="mycothiol_INO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inos-1-P_synth" evidence="2">
        <location>
            <begin position="191"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="38728" checksum="747BDB8D9C32F180" modified="2009-10-13" version="1">MGSVRVAIIGVGNCAASLVQGVEYYKDADPNAKVPGLMHVQFGDYHVSDLEFVAAFDVDAKKVGLDLADAIGASENNTIKIADVPPTGVVVQRGHTNDGLGKYYRQTIVESDAEPVDMVAALKAAKADVVVCYLPVGSQSAVEYYAQVAIDAKVAFVNALPVFIAGTKAWADKFEAAGVPIVGDDIKSQVGATITHRVLAKLFEDRGVVLDRTMQLNVGGNMDFMNMLERERLESKKISKTQAVTSQLSHDLGAGNVHIGPSDYVAWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRCAKIALDRGIGGPILSASSYFMKSPPVQYFDDEARDAVEAFIKGEVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVI7</accession>
    <name>C7PVI7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FMN-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0391"/>
    <dbReference type="EnsemblBacteria" id="ACU69343">
        <property type="protein sequence ID" value="ACU69343"/>
        <property type="gene ID" value="Caci_0391"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0391"/>
    <dbReference type="eggNOG" id="COG3976">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1812298_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_bind" evidence="1">
        <location>
            <begin position="62"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14780" checksum="C13ABCBE547D93CB" modified="2009-10-13" version="1" precursor="true">MRIPLIKTLLSLAGTVGTMGGLLAMKTSAHGLAPQPLQAAKVVHDRTAGATMTVTGPAIPVTHGIVQVRITLTDGHITDVSATSLPHDNDDSWTRSVTAAMVLDREVIAKQSAHIDGVSGATYTSKAYKASLQAAIDAGYRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW60</accession>
    <name>C7PW60_CATAD</name>
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        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4444</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4444"/>
    <dbReference type="EnsemblBacteria" id="ACU73308">
        <property type="protein sequence ID" value="ACU73308"/>
        <property type="gene ID" value="Caci_4444"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4444"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019393_0_0_11"/>
    <dbReference type="OMA" id="GPWTDRT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981318" evidence="1">
        <location>
            <begin position="35"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="592"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="794" mass="79831" checksum="D1712D117BACF9A1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW73</accession>
    <name>C7PW73_CATAD</name>
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        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4458</name>
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    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793050.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4458"/>
    <dbReference type="EnsemblBacteria" id="ACU73321">
        <property type="protein sequence ID" value="ACU73321"/>
        <property type="gene ID" value="Caci_4458"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4458"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012341_2_0_11"/>
    <dbReference type="OMA" id="GGSVWFL"/>
    <dbReference type="OrthoDB" id="856767at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982615" description="FtsX domain-containing protein" evidence="7">
        <location>
            <begin position="32"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="699"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="753"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="784"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="284"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="822" mass="82975" checksum="D30C1403D09C545D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWC9</accession>
    <name>C7PWC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4514</name>
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    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
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                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4514"/>
    <dbReference type="EnsemblBacteria" id="ACU73377">
        <property type="protein sequence ID" value="ACU73377"/>
        <property type="gene ID" value="Caci_4514"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4514"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074359_1_0_11"/>
    <dbReference type="OMA" id="AWNMTAD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="168"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="32286" checksum="2F5E4C7CFE8FC763" modified="2009-10-13" version="1">MRQAVPEDLPILRVLARASLTHDADAEAVVDLLWSASAESCRVVAEHAGQIIGFALGSLRPAHDDVPATGHVELLAVGPEHRERGHGRALLTELERRLTAAGVTRLRIRGNPPYFAWPGIDVRYTPAVCLAASAGYERLLDCNNMLVELAAADLATERDEQRLTDAGIEVRRGRPEDEKALRVWSDREFGGTWGEEAAMALRHELPRLHVAVRDGAFLGFAGHGIQRFAMFGPMGTDPAARGLGIGAVLLRRCLADMREAGIEVAEIGWVGPVRYYSKTVGATLGRVFWAFEKSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK2</accession>
    <name>C7PWK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795011.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6430"/>
    <dbReference type="EnsemblBacteria" id="ACU75282">
        <property type="protein sequence ID" value="ACU75282"/>
        <property type="gene ID" value="Caci_6430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6430"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144710_0_0_11"/>
    <dbReference type="OMA" id="CLNYASI"/>
    <dbReference type="OrthoDB" id="1831758at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13288" checksum="315892A6C3AF6137" modified="2009-10-13" version="1">MTPANDIGQPGGGRRYPLVVVRRASQGRLTLEDVAGRSGVTSQLIRRFVALSVLDAQRDDAGQLWFDARAPATVARALRLHAGLGLNYASLGLVLDLLDRIDQLESALRRSGRPAKEFPPWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWK6</accession>
    <name>C7PWK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chloride channel core</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6434"/>
    <dbReference type="EnsemblBacteria" id="ACU75286">
        <property type="protein sequence ID" value="ACU75286"/>
        <property type="gene ID" value="Caci_6434"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6434"/>
    <dbReference type="eggNOG" id="COG0038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015263_5_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="481"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="600" mass="60500" checksum="964FB60A84CC75CA" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWN9</accession>
    <name>C7PWN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795048.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6468"/>
    <dbReference type="EnsemblBacteria" id="ACU75319">
        <property type="protein sequence ID" value="ACU75319"/>
        <property type="gene ID" value="Caci_6468"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6468"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="GHAASMY"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="22"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU75319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="534" mass="54362" checksum="D3066D02F2A1B630" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA6</accession>
    <name>C7PXA6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0511"/>
    <dbReference type="EnsemblBacteria" id="ACU69457">
        <property type="protein sequence ID" value="ACU69457"/>
        <property type="gene ID" value="Caci_0511"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0511"/>
    <dbReference type="HOGENOM" id="CLU_2988183_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026334">
        <property type="entry name" value="FxSxx-COOH"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04268">
        <property type="entry name" value="FxSxx-COOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="57" mass="5994" checksum="B34DD12E1A773BFB" modified="2009-10-13" version="1">MLHPKNDAKPGQATAVTDSRDTPLGRVSESAASTLFRIVRACDEPLTPPVAAFDASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA8</accession>
    <name>C7PXA8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminoglycoside N(3)-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0513</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12665"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57921"/>
            <dbReference type="ChEBI" id="CHEBI:77452"/>
            <dbReference type="EC" id="2.3.1.81"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the antibiotic N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.81" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0513"/>
    <dbReference type="EnsemblBacteria" id="ACU69459">
        <property type="protein sequence ID" value="ACU69459"/>
        <property type="gene ID" value="Caci_0513"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0513"/>
    <dbReference type="eggNOG" id="COG2746">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060091_0_0_11"/>
    <dbReference type="OMA" id="ARCLMIG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046353">
        <property type="term" value="F:aminoglycoside 3-N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003679">
        <property type="entry name" value="Amioglycoside_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028345">
        <property type="entry name" value="Antibiotic_NAT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11104">
        <property type="entry name" value="PTHR11104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02522">
        <property type="entry name" value="Antibiotic_NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110710">
        <property type="entry name" value="SSF110710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29708" checksum="DBAA6E9C061DF3DD" modified="2009-10-13" version="1">MSDSLEATHHAPIVRSRQQPCSRQQLAEDLVRLGLQSGTDALINSSLRAIGPVDGGAATVLAALRAVLGPRATVVVPSQTPANSATSSAHREAVAGMTAVEIAGYRERFPPFDPARTPSAGMGAFAEHVRLQPGACRSGHPTSSFAALGPAAERITALHPLHSHLGPESPLGALAESGAQVLLLGVGFAKCTAFHLAEYRVRPETRTYSSKLADLSRPGGGGRWIEYRAIRLDASDFDRLGADLAASRSWVRNGTVGAAPSACFPLASAVRFAEQWLSEHRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXJ5</accession>
    <name>C7PXJ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thaumatin pathogenesis-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786741.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2530"/>
    <dbReference type="EnsemblBacteria" id="ACU71448">
        <property type="protein sequence ID" value="ACU71448"/>
        <property type="gene ID" value="Caci_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2530"/>
    <dbReference type="eggNOG" id="ENOG503366T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_775427_0_0_11"/>
    <dbReference type="OrthoDB" id="1438855at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="PTHR31048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="SSF49870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="357" mass="36351" checksum="62D9499B603EA36A" modified="2009-10-13" version="1" precursor="true">MTGHRSGRRAYRPIVAGGLAAAAALALVLWIAGFGSGRSGGGADQAANSTTQLSTSGPASSAQSLPTPSSFATSATTSTRPPPASTTASTPTTSKSKSASTSTTVGASAAKPTTTNPASVTRPAGGHLITVVNADNQTIWAATNPNAQHPIPLTGWRLDPGQSVTFAVPAGWGGRVWGRTGCSFSASGAGHCLSGDCGGVFQCKGAGAPPATLAELTLDSFDGLDFYDVSLVDGSNLPMYINTSHRVGTDPVSQNGCYQGACTKPIVCPGPMQVKAAGQVVACTTPCAAFGGDAYCCRGQWAGRENCDPAKWPVDYAKLVYKDAEPYAYSYAFDDSATMSCKGDCDYRIVFGTSSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY69</accession>
    <name>C7PY69_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase GroES domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795088.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6510"/>
    <dbReference type="EnsemblBacteria" id="ACU75359">
        <property type="protein sequence ID" value="ACU75359"/>
        <property type="gene ID" value="Caci_6510"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6510"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OMA" id="IHARADQ"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="31402" checksum="85FEB4697C7770B6" modified="2009-10-13" version="1">MQAVRYHDYGDHTQLVLEEVPTPDPGPGQVLLKVVATSFNPADAALRAGYLREMLPLELPHTPGVDVSGTIAALGADVTGWDVGAAVAGFLPLNAAGAAAEYVLAPAEVLAAIPDGVDPVDAAALPAVGLTAWQALFEHASLTAGQRVLINGAGGAVGSYAVQYAHQAGAEVTATAAPRSADRVHGHGADHVIDYTATPVHQAAEGTFDVVLNLAPTTPEDTDALAALTADGGVFVTATTAPTSEPGRGVRVVRMAVRSDAAQLADLLAQAAAGTLRIDIANRRPLAELPDIHARADQGTLGGKTVITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYE5</accession>
    <name>C7PYE5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6589"/>
    <dbReference type="EnsemblBacteria" id="ACU75435">
        <property type="protein sequence ID" value="ACU75435"/>
        <property type="gene ID" value="Caci_6589"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6589"/>
    <dbReference type="eggNOG" id="ENOG50347BB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133115_0_0_11"/>
    <dbReference type="OMA" id="WESATAE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982697" evidence="2">
        <location>
            <begin position="49"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="171" mass="16355" checksum="14B7A7AFE6E13311" modified="2009-10-13" version="1" precursor="true">MLTTISSVHRRRLSVGAAAFAVMALSVAGCGSGSSSAGASASSQVSSAASSLASQGGSAASQAASSASSAASSALAQVTDGVTAASDVTAGPATTGSDGRAECPLTVRNPTSDPHDYTISVAFDDPNGNLLDATVVTVSAVPANGTATATARSNRDLSGSIAAKITAAVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYU7</accession>
    <name>C7PYU7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8600"/>
    <dbReference type="EnsemblBacteria" id="ACU77419">
        <property type="protein sequence ID" value="ACU77419"/>
        <property type="gene ID" value="Caci_8600"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8600"/>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078491_2_0_11"/>
    <dbReference type="OMA" id="KIVGRHA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="1">
        <location>
            <begin position="31"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="197" mass="19345" checksum="976692EF3A7E4C2F" modified="2009-10-13" version="1" precursor="true">MRIPYAVTSVALVVTGAVLFTVAAWQISGRAPVLAVAQPIAAGQVVTQDDVKIVKVGAASDLGLVPSINEAEVVGHVAAVPLAAGTLLTAHMVGTADFPPPGQAVIGVALKAGAFPPRLGVGDRVNVWPGPDVAAVASASSAPVALASNAVVTSVGSADSVGTTVVTLLVDAQAAPKVTQAPSLSVVEVSPNEVGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYZ2</accession>
    <name>C7PYZ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, BadM/Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784843.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0612"/>
    <dbReference type="EnsemblBacteria" id="ACU69548">
        <property type="protein sequence ID" value="ACU69548"/>
        <property type="gene ID" value="Caci_0612"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0612"/>
    <dbReference type="eggNOG" id="COG1959">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107144_1_0_11"/>
    <dbReference type="OMA" id="KASTDYG"/>
    <dbReference type="OrthoDB" id="1794390at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="155" mass="16518" checksum="00F8FC7A9EA2F211" modified="2009-10-13" version="1">MKLPTSTEWVLHCAATLAQLRPAETASAAQLAAYYDLPAPYLAKQLQALTRAGILSATTGPRGGFRLARAAKDITMLQIVEAVDGAAAPYECREIRQQGRGGLTPDECQETCPLARTMAEAHTAWRASLTAVSLADILAELPSGAPTRTRRILMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZA5</accession>
    <name>C7PZA5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2646"/>
    <dbReference type="EnsemblBacteria" id="ACU71562">
        <property type="protein sequence ID" value="ACU71562"/>
        <property type="gene ID" value="Caci_2646"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2646"/>
    <dbReference type="eggNOG" id="ENOG502ZAB6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_626647_0_0_11"/>
    <dbReference type="OMA" id="REFYEHT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="47325" checksum="BF7F85690E17793B" modified="2009-10-13" version="1">MTTPEDPRDHPAGDKPEAPGAPSRTQQIVTAGVLGALAGAALGSHRGRRRTAWGALAGAACLGTVEAVARARQQPGQIPSWWARVAASGAIAAPVGWAAGRATGAGPVVVGTAAGAVAGGLGLRPQKVALGPVLGAAIGRGLATRPGLKAPAVVAAATVVGFRAVSALVFPDPQVSLLAERVTARDLPFVVPLEARTRYVGTGYVRDLAKVLGGVYVPATEDVGIVASLDELEGPDFAPADVDPLVREFYEHTTRFALDIVPEWRTWVRPGYLLYRNLLARPLGQANVPMNQRETLRGIHSRIDTIVQADDNTVTVRGWIRSFADNDEPIYMGIYTTYRNGGRGYVSVGFPLPQASFTATLLPKARPGGGLVLTSRSDLDQPGHYLTYIDSESRELTSAVVQGFAEQLDVYVQDGELRAEHAFWVFGLPFLVLHYRIQRKPKAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZC5</accession>
    <name>C7PZC5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786875.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2666"/>
    <dbReference type="EnsemblBacteria" id="ACU71582">
        <property type="protein sequence ID" value="ACU71582"/>
        <property type="gene ID" value="Caci_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2666"/>
    <dbReference type="eggNOG" id="COG5485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100997_5_2_11"/>
    <dbReference type="OMA" id="FTGTHNG"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="15555" checksum="1ED64F77764CE319" modified="2009-10-13" version="1">MDTIEKNKQTVIAFIQAMFTQGDLSAADTYLAADFVDHDPPLGFGGRDGLRDAAATFRVAFPDWHSDLMFLVAENDLVVEQFVASGTHQGEVMGVPGDGRTVTLPGINIFRLRDGRIVERWGRLDELGLLRQLGLVPTPVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0P4</accession>
    <name>C7Q0P4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784967.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0737"/>
    <dbReference type="EnsemblBacteria" id="ACU69672">
        <property type="protein sequence ID" value="ACU69672"/>
        <property type="gene ID" value="Caci_0737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0737"/>
    <dbReference type="eggNOG" id="ENOG50333DA">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066641_0_0_11"/>
    <dbReference type="OrthoDB" id="1583535at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981368" evidence="2">
        <location>
            <begin position="36"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="335" mass="33248" checksum="2035FF5C738D6330" modified="2009-10-13" version="1" precursor="true">MNRRRIAIGVSSVSGLAVVAAGAMSMFGAGGSANAVDLHAAPVAAVSDAAAATARAATAQADTVVTVASPAVPAQGKTPAAAAQNLSMHGSGQFDFGKRIGSLDLTMPSGALNEVMTPSTLYVRRAAAAATATAAAVPASAWSQTPTAQVSDGDLISGGATDPSLVFAMLGGVQSGVREVGQDTVRGVPVVHYQGTLDLGQAAAALAGPASAKSTNSADAVADKQALTNASQAFTTTKVPFDAYLDAQGRVRRFVATFAFMENTATKAIAQVTSATELYGFGTPVAVATPSVPPPAPKTAPKTAPKTAPKASESTPGHRATTPSAHPTSPTSSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0S3</accession>
    <name>C7Q0S3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Drug resistance transporter, EmrB/QacA subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0766</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784996.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0766"/>
    <dbReference type="EnsemblBacteria" id="ACU69701">
        <property type="protein sequence ID" value="ACU69701"/>
        <property type="gene ID" value="Caci_0766"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0766"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="OMA" id="FFANEPP"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="499" mass="51060" checksum="385BB9C5DE9F13AA" modified="2009-10-13" version="1">MTDTIQTAAADSGAVADKDPRRWKALIFIAVAQLMVVLDGTIMNIALPSAQRSLGFSDGSRQWLITGYTLAFGSLLLLGGRIADYTGRKRALLVGLTGFALASAIGGVAPDFAVLLIARCLQGAFGALLAPAALSLLATTFTEPLERAKAFGLFGGVAVGGNAIGLLLGGLLTEYLNWRFCLYVNIPIAAIALAGGMKEIRESRAEGRMKLDLPGVLLVVGGLVAMVYGLGQASTDGWGSATVLGCLIGGAVLLAGFLVVESRVEAPLLPLRVLLSRTRGGSYLAVGTAAVGMFALFLFLTYYMQDVKKYSAVMTGVAFLPMTAAIMISAVLLGSRLVPKVAPRLLMVPGMLVAAGGLALMTTVKPDTGYVAGVLPVEVLVGLGLGLVMAPAMNYATHNVRPEDAGVASATVNTSQQVLASVGIALSNTVAASATTSYLKLHRPSPTLVNDAVVHGFTTASGVAAAIVLGGAVIVALLMNTGKPDPSQASADGPVAVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0U9</accession>
    <name>C7Q0U9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0792</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0792"/>
    <dbReference type="EnsemblBacteria" id="ACU69727">
        <property type="protein sequence ID" value="ACU69727"/>
        <property type="gene ID" value="Caci_0792"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0792"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_18_11"/>
    <dbReference type="OMA" id="RRFVADM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="220"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="287"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="505" mass="54853" checksum="5E2A73A7A1FA94ED" modified="2009-10-13" version="1" precursor="true">MLRERPKSAKLAKAPKVQELPRRADQERRRHKRPLRLTGLRMRLLAAFAAVALMTSAAVTGVSYVLTRQSLMNRVNQSSVQQFKAAVAQTRESLQEARPSTTPVDLSTIGFKLLAASGTDWVLYRTGMNYGTTENYLSYNSIPPKLRVAAQKNIAWQRTRVGNQPYLIVGSSVQPNGIEVYNFVSLESQQEDLNRLAQNSAIAAAIAIAISLLLGLLASRGVLLPLRRLGIAARRLGAGKLDTRVEVKGNDEVADVSRTFNETAEALERSIAELRSLEAASRRFVADVSHELRTPLTAMTAVSDMLEEATDVGDESAPAAQLIVTETRRLARLVEDLMEVSRFDAGTAQLRREDVDLVALVHGCLDARGWTGRVTLNVPPSLAVTVDQRRIDVIVANMVGNAIKHGGEGPVELSIGAFGPNLVLQVRDHGPGIPPDALEHIFERFYKADKARVRSEGSGLGLSIAYENAHIHGGELAGGNHPDGGAVFTLRLPLQATIPAQEAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0V3</accession>
    <name>C7Q0V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785026.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0796"/>
    <dbReference type="EnsemblBacteria" id="ACU69731">
        <property type="protein sequence ID" value="ACU69731"/>
        <property type="gene ID" value="Caci_0796"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0796"/>
    <dbReference type="HOGENOM" id="CLU_2435452_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982768" evidence="1">
        <location>
            <begin position="32"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="90" mass="9080" checksum="504023BCC5BBCEF4" modified="2009-10-13" version="1" precursor="true">MSKNPRSAARRALSLAALSGLGLAAAPAAHAAAGLGATQLYPLAHTPLDLLSNNLHVPVGGMDLSTFGVTAPFHDGLPLREVPVVGPLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0X4</accession>
    <name>C7Q0X4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0817"/>
    <dbReference type="EnsemblBacteria" id="ACU69752">
        <property type="protein sequence ID" value="ACU69752"/>
        <property type="gene ID" value="Caci_0817"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0817"/>
    <dbReference type="eggNOG" id="COG2114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043761_2_0_11"/>
    <dbReference type="OMA" id="LQPMWQR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="277"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="45414" checksum="714F870C4D3D06F8" modified="2009-10-13" version="1">MARRVPGDGGRKAARGGGTAGRAESAQTAASGTAASGAAGSNGASSNAGGSGNTGTSGNSVVSSTSGTSSTSSNSGTATPPGLPATAGEVARALIQAQVQTQAEARAQNHARSRSKRKANGDELEALLLGGVPRHTAYEVCKAAGIPYDEARRYWRAMGFADVGQARAFTDADVDALLRLGGMPRSGLFTEDFAVQVARSMGQTTARLAEWQVDVLFDAFDTAGVGSEEMAEFGYRIGRRVLPELEELLVYVWRRQLAAAAGRVRQQLQEHAEGLQAVGFADLVSFTRLSRQLSEEELARLVSVFEANAADTVAYGGGRLIKTLGDEIMFAADSPARAARIALDLLASMRRTEAVPELRIGVAYGHVVQRNGDIYGTTVNLAARLTSLAEPDQIVVDPELAKALASDSDFALEAIGTRMVRGLGEIEPSALTAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1H6</accession>
    <name>C7Q1H6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793434.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4844"/>
    <dbReference type="EnsemblBacteria" id="ACU73705">
        <property type="protein sequence ID" value="ACU73705"/>
        <property type="gene ID" value="Caci_4844"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4844"/>
    <dbReference type="eggNOG" id="COG5592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846466_0_0_11"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="2">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="188"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="328" mass="36404" checksum="9E97C85BE83D2ECF" modified="2009-10-13" version="1">MSDVTKSVDVEVPLRTAYNQWTQFESFPEFMSGVIAIRQLDDRHTHWVTEVAGARREFDAEIVEQLPDERIAWRSVDGDVRHSGIVTFRPLGDHTTRVTVDLEWEPEGLLEKAGGAMGVDRLQVKADLERFRQFIEERGNETGQWRGQVPETQVAAVPTGNAEPLAGTAAPLADAQQAAGPDPSANDVVDVLVAQHAQVKDLMARTAASEGADKQRLFTALVDLIKTHEKGEQRVVHPVTRSSVEGGAATANARLGEEERADQLIAEVKTMTADSPEFDAWFEQLRQAVLDHAEHEEREEFPKLRRELTAARLHTMAEELVAVQTAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q217</accession>
    <name>C7Q217_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent pyridine nucleotide-disulphide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797278.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8739"/>
    <dbReference type="EnsemblBacteria" id="ACU77554">
        <property type="protein sequence ID" value="ACU77554"/>
        <property type="gene ID" value="Caci_8739"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8739"/>
    <dbReference type="eggNOG" id="COG1251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_4_11"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="326" mass="33746" checksum="814E35C24CF5D414" modified="2009-10-13" version="1" precursor="true">MTRKIVVVGWGLAAHRLVTGLLAADTDVDVIVYAGEGGTAHDRSALPGTLTGAGAGLPTPSDPRLTLHAGVRAVAVDRMHRFVHGSDHWVQPYDTLVLATGANAMLPPIKGLRTDDGQDLLPGVHSSHSAADFQRLAEAASAATHAVVIGGSTIGLDVAAALRTMRAADPLHVELVDQMPAAPEITSADAYLTLRRTGVIAYQDCRVRALTAGRGGGLEGVVLADGHRLACDLAVIACGTAPNTALAWTSGLAVARGIVVDDTLRSVSDPHIHALGACAEHRRSLSGRRETVLAQADVLAARLSGVDPYRTYFSGLRSGAQLALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q238</accession>
    <name>C7Q238_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797299.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8760"/>
    <dbReference type="EnsemblBacteria" id="ACU77575">
        <property type="protein sequence ID" value="ACU77575"/>
        <property type="gene ID" value="Caci_8760"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8760"/>
    <dbReference type="eggNOG" id="COG1545">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119412_0_1_11"/>
    <dbReference type="OMA" id="MQACANC"/>
    <dbReference type="OrthoDB" id="1756670at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022002">
        <property type="entry name" value="DUF35_Znr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12172">
        <property type="entry name" value="DUF35_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF35_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="51"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="15473" checksum="FF2E16221F84472F" modified="2009-10-13" version="1">MLKPLVDDDGAPYFAYAAKGELRMQACANCGEVLFPPRPMCPRCQGMEFAWKLMSGRGHVWSFAVPRPPLLPDYAALAPYPVVVVELEEDRRLRLVGNLVAAEDADIDSVDPATIEIGQPVRAVFREIEGLFVAAWTPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q254</accession>
    <name>C7Q254_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8776"/>
    <dbReference type="EnsemblBacteria" id="ACU77591">
        <property type="protein sequence ID" value="ACU77591"/>
        <property type="gene ID" value="Caci_8776"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8776"/>
    <dbReference type="eggNOG" id="ENOG5033NEF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_592767_0_0_11"/>
    <dbReference type="OMA" id="TQYIPPV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="461" mass="48152" checksum="1B2D8006D40F7397" modified="2009-10-13" version="1">MPHTAQFAPVERPGQAFSPAPPEDDGYPGGQIPESSGFSWRLPGQPAPVQHAQGGIPNEFDHLFRDAPADDRRSLLPNQGTIGVSVPGAAGYSGPSYPQNPATGAQRPAPGPGPGPQPTQSLPPADATGPQTAVYQPPTQDQVGYPDQTGYQQQGGYQNQGGYQDQGGYQDQTGYQDQTGYQNQTGYQNQGGYGQQQMPGHGYDQSGYQGQTQQQGGYDPDQHTQAIPRVQPQMYGGGRNNGGPDLLMATGPDRRQSNRTLLVAIGVFVVLIVVAVVAFSGGGGKSKTNTAGKSTNTDTPPPTTSVSAPPGVDPAAKAQADALYGIIAQSHALREKANASVEAVQQCKNVATNKQTFTDVATQRQAQADGTKAAAVDKLPGGAQLQQDLITSWQLSAESEKDYAAWSNDNLTCTGKPTANDNLNRASSAGGKAGTAKNAAVRDWNAFATKLGVHTITISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q258</accession>
    <name>C7Q258_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron (Metal) dependent repressor, DtxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_8780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8780"/>
    <dbReference type="EnsemblBacteria" id="ACU77595">
        <property type="protein sequence ID" value="ACU77595"/>
        <property type="gene ID" value="Caci_8780"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8780"/>
    <dbReference type="eggNOG" id="COG1321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069532_0_0_11"/>
    <dbReference type="OMA" id="DAQLMYT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU77595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="238" mass="26299" checksum="925582045521B863" modified="2009-10-13" version="1">MSSDLIDTTEMYLRTIYELVEEGIVPLRARIAERLGQSGPTVSQTVARMERDGLLTVEGDRHLELTDDGREQATRVMRKHRLAERLLTDVIGLAWEDVHVEACRWEHVMSEAVERRLLELLDHPTESPYGNPIPGLAELDDTVGEQEAFLDGDVANLRDVVERGARSATAQNLVVRRLGEPLQNDPQLMLRLRRAGVQPGQTVRATVSPGGVLLGSVGETAELDLDLAGHVFVTVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q283</accession>
    <name>C7Q283_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797344.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8807"/>
    <dbReference type="EnsemblBacteria" id="ACU77620">
        <property type="protein sequence ID" value="ACU77620"/>
        <property type="gene ID" value="Caci_8807"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8807"/>
    <dbReference type="eggNOG" id="COG1695">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089258_4_0_11"/>
    <dbReference type="OMA" id="NRPERTT"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="21"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="215" mass="23697" checksum="03C896760F8CA04C" modified="2009-10-13" version="1">MAAAQNSAAGATRRSPLALAVLALLGYKPLHPYGVQRLLKEWGKENVVNVGQRASLYKTMERLTAAGLIAVRETERDQQYPERTVYELTDAGREAARAWIDDIVRVPRPEYPEFPAALSFLMVLEPEVVLAALSERRETVAKTLAQAKQGMAEARQYGLPKVTLLDDEYLVAVTEAELRWIEGVVAELESGELTWSLAELQPFDEADTDAGTPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2G3</accession>
    <name>C7Q2G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785100.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0872"/>
    <dbReference type="EnsemblBacteria" id="ACU69805">
        <property type="protein sequence ID" value="ACU69805"/>
        <property type="gene ID" value="Caci_0872"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0872"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="OMA" id="TGSWYGR"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="212" mass="22700" checksum="E7050A742142620B" modified="2009-10-13" version="1">MHPGRTPQVGGRSAGQGRARDSTIDARILAAAKRQLAVLGYEGMSIAAVAAEAGTTRQALYRRWPSKADLAGAAVASAEDAPTDPPRESPGIADPFADLVAELTDFQRGVSRPGRLSLVGTMLQDNTERQVRERYQARVIHPRRRRIAAILQAAQDLGLIDQDADLTVAVTMCTGSWYGRALAGDPVPADWPTRTAALVWRAVGGDVRRTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2W4</accession>
    <name>C7Q2W4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787149.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2947"/>
    <dbReference type="EnsemblBacteria" id="ACU71856">
        <property type="protein sequence ID" value="ACU71856"/>
        <property type="gene ID" value="Caci_2947"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2947"/>
    <dbReference type="HOGENOM" id="CLU_2714972_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="72" mass="7737" checksum="4D34E9B8B2281A60" modified="2009-10-13" version="1">MSDSQMTVADDASTFPPQGRLIHVAHGFQWNSIAELLQRAGVTLFEIPPGPSVPDQAGEDIPTFGLMLRSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3D2</accession>
    <name>C7Q3D2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monosaccharide-transporting ATPase</fullName>
            <ecNumber evidence="8">3.6.3.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_5008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.3.17" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5008"/>
    <dbReference type="EnsemblBacteria" id="ACU73868">
        <property type="protein sequence ID" value="ACU73868"/>
        <property type="gene ID" value="Caci_5008"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5008"/>
    <dbReference type="eggNOG" id="COG1172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028880_3_1_11"/>
    <dbReference type="OMA" id="FSLMVPN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="346" mass="34494" checksum="765DA239143BE988" modified="2009-10-13" version="1">MTTTSALGQRAEEQLGTGGGGSRIRALVARGGAQSVGLVAALVFVLVLFGSLNANYLSWQNIQVIAEAVTISGLLAVVQTVVIIIGALDISVGSQAGLASVTSAMVFTSAGSNAFAGIGAALAIGAVIGVVNGAIIVYGRVNAVIATLAGLAAYKGVAQLVSDGRAQGYVLNDSIFVFLGRGKIAGLPVMVWLLLVVAAAVHVLLKYTDIGRNLYAIGGNDTAARLAGINLNKYILAVYALSGAVAAVAGILLTARTGSGQPVSGSEGLELQSITAAALGGCALKGGKGGVGGTLLAVALLGALQNGLTVQGINAFWQNIAQGALLVVAVVLQQRRSRERAVGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S4</accession>
    <name>C7Q3S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797406.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8869"/>
    <dbReference type="EnsemblBacteria" id="ACU77682">
        <property type="protein sequence ID" value="ACU77682"/>
        <property type="gene ID" value="Caci_8869"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8869"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_7_2_11"/>
    <dbReference type="OMA" id="ARHLVCR"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="35552" checksum="860BB82DA8FD7D2F" modified="2009-10-13" version="1">MDIGVLLPTGTAQWEPGDDPRGVVALALRAERIGFSSLFVNDSLISPRIEALTMLAALAPATAGVTLGTGALLPFMRRPVQAAQSLASIDVLSGGRLVVAVGAGFPGRFGRPMYTLSELPWERRFQRLDETVALWRAVWAGASSFHGELVRFDDLPPATKPFRPEGPPIWLGGATPAALARTAKHYDGWLPYPPDPADYRSGLTAIQQTAQDEGRSADAVTPALFVTVRVDTDEAAGRAQLDLYARANYGMPLADLQTIQAVVTGTADQVAAGLGAYIAAGARHLVLRLGAIGLAAQEEQLDRVAALIGRLADCAAWDLSSAAPDRTPAASRRPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U0</accession>
    <name>C7Q3U0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797422.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8885"/>
    <dbReference type="EnsemblBacteria" id="ACU77698">
        <property type="protein sequence ID" value="ACU77698"/>
        <property type="gene ID" value="Caci_8885"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8885"/>
    <dbReference type="eggNOG" id="COG1131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="MCDYLLV"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30434" checksum="71A6ABA930B98865" modified="2009-10-13" version="1" precursor="true">MSEFAIQTESLGKRYRKLWALKDFSVSLPANKVIALVGANGAGKSTLMSIAAGILPASEGELRVNGRVVLLSQEKPLYRSFTVADMLAFGRHLNRVWDQERALNWLGRFDIPLNRPCGKLSGGQQTQVAMAVALGARPSVLLLDEPLANLDPLARREVTGELLAEVADSDMTVVLSTHVVAELAGVGDYLLLLGQGRGKLDGDVEELLAQHARLTGPRADAPPVEGEIVQAQHTERQSTFVIRTLLGADTPLAEPWKAQPLTLEDLVLAYLKPHRSPGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q495</accession>
    <name>C7Q495_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1029"/>
    <dbReference type="EnsemblBacteria" id="ACU69955">
        <property type="protein sequence ID" value="ACU69955"/>
        <property type="gene ID" value="Caci_1029"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1029"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="ATMLKPN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="276" mass="28170" checksum="270E2B307850617A" modified="2009-10-13" version="1">MSSAPTALGRREAGGSDHVVIALDDVTKSYPGGVSALRGVSLVVRRGEFVGVVGPSGSGKSTLLHILGTLDRPSSGTVRVDGWDIADLSDRELSALRGATIGFVFQQFHLTSGLSAVEAVADGLLYAGVRPAERRQRASAALHRVGMAHRLDHRPHELSGGERQRVAIARAVVGDPAVLLADEPTGNLDSASGHAVMALLRSLNAAGTTIVLITHDRDIAAGLPRRVEIRDGEVVADSAAACAAAFASASASPSASQPTSPSAPSSLSAPSAEVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4B8</accession>
    <name>C7Q4B8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Coagulation factor 5/8 type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785272.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1052"/>
    <dbReference type="CAZy" id="CBM32">
        <property type="family name" value="Carbohydrate-Binding Module Family 32"/>
    </dbReference>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69978">
        <property type="protein sequence ID" value="ACU69978"/>
        <property type="gene ID" value="Caci_1052"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1052"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_2_2_11"/>
    <dbReference type="OMA" id="LMLWMSH"/>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041351">
        <property type="entry name" value="Ig_GlcNase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="PTHR43536"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18368">
        <property type="entry name" value="Ig_GlcNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981408" evidence="5">
        <location>
            <begin position="40"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="6">
        <location>
            <begin position="51"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="6">
        <location>
            <begin position="612"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="6">
        <location>
            <begin position="763"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="630"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="776"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1362" mass="146523" checksum="5CC08A8AFF0C87FE" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4E8</accession>
    <name>C7Q4E8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787210.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3008"/>
    <dbReference type="EnsemblBacteria" id="ACU71917">
        <property type="protein sequence ID" value="ACU71917"/>
        <property type="gene ID" value="Caci_3008"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3008"/>
    <dbReference type="HOGENOM" id="CLU_2080538_0_0_11"/>
    <dbReference type="OrthoDB" id="425206at201174"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="117" mass="13181" checksum="BF558574092F47BF" modified="2009-10-13" version="1">MSTPTENVRTLPGDLEFLTPHCPICGDYTDVYPDGLQCDRCGIAWDSDGTNPERLDPDAKQCSSLYRPTRRCANPEHVDVEYRCWQDAGHLGDDHHNPDLFYSWTTAEQVAPAGVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4M4</accession>
    <name>C7Q4M4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Substrate-binding region of ABC-type glycine betaine transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_3084</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787286.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3084"/>
    <dbReference type="EnsemblBacteria" id="ACU71993">
        <property type="protein sequence ID" value="ACU71993"/>
        <property type="gene ID" value="Caci_3084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3084"/>
    <dbReference type="eggNOG" id="COG1732">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038355_1_2_11"/>
    <dbReference type="OMA" id="KDPAWKN"/>
    <dbReference type="OrthoDB" id="770506at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980589" evidence="2">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="38"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="302" mass="31639" checksum="44415B1C9291A209" modified="2009-10-13" version="1" precursor="true">MSKSPRTLLSTAAVALAALAATACTSGNPLVPGPKKGQVTVGSANFPENVLLADIYASALKAKGVKVGIRFNVGSREVLYQQVQQGSLTVLPEYNGALLAYLDSKTRAATTAEIDAQLRATLPAKLEILDPSPAEDKNALVVTAATAAKDHLTAIGDLAPYAAALSIGGPPEFKERYQGLPGLKDKYGLTFKSFASLDTAGPITVKALADDSVQVATLFTTDPNIVSHNFKVLTDPQQVFTAQNVTPLAYRASMTPTATATLNEVSAKLNTAALVGMMAQIMNQKRDIDVVADNWLKGAGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4Z6</accession>
    <name>C7Q4Z6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5084"/>
    <dbReference type="EnsemblBacteria" id="ACU73944">
        <property type="protein sequence ID" value="ACU73944"/>
        <property type="gene ID" value="Caci_5084"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5084"/>
    <dbReference type="eggNOG" id="COG3463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029114_0_0_11"/>
    <dbReference type="OMA" id="CTAAERI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018650">
        <property type="entry name" value="STSV1_Orf64"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09852">
        <property type="entry name" value="DUF2079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="506" mass="55104" checksum="B1DD8BEDEB7F41DA" modified="2009-10-13" version="1">MPEDLAERPAARRSPHGYVLAAMVVLVAVAYAVYELTVYRTYRSSTYDLVIFDQAVRSYSHFHLPVAIVKGVHNNFGAQFTVLGDHFSPIIAVLAPLYWISGNPKTLLVAQSVLLAGAIPWLWVYARRASGTFAAYCVVVIYAVSWPVAAAVAFDFHETAFVPLLSAVLLERYQAGRRVHAVLAACLLLLVKEDIGLLVAGFGLFLVTGCRLPAQEKYARQRLLGAAFVVGGVGWTLVATHVFIPAFGGRGNYYWAYTALGPDLPSATTHAIAHPVSTLQLFGTPSIKITTMTWLVVPLLLLPLASPLTLMVIPALAARMGSNLFPNWWGEEYQYNAELIVPLVAAGLDGALRINMLLTRLRPIWTWTKRIGPAWAAGALMVSVAVIPKFAFDAYGQSSFYRLTPADRAAATAAGHVPDGVVVEAASLIGPHLSARDTVLLLDKTPRWAPWVVAQISDPTFPISDAAAQKARVTYLETNGYRPVWHDDFYVVLTKPGSVPDYTRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q531</accession>
    <name>C7Q531_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793708.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5120"/>
    <dbReference type="EnsemblBacteria" id="ACU73979">
        <property type="protein sequence ID" value="ACU73979"/>
        <property type="gene ID" value="Caci_5120"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5120"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_3_0_11"/>
    <dbReference type="OMA" id="VKWGGGF"/>
    <dbReference type="OrthoDB" id="2025630at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="205" mass="20264" checksum="FFA6CE844FFE0676" modified="2009-10-13" version="1">MASRGLRTDLGLLALRLGTGGILIAHGTQKLFGWFGGRGPKGTAATMHAMGFRPGLPNALTAGLSETAGGTLLALGAATPAGGAAALGAMSAAAAVHHPSGFFNSTGGYEYPAFLALTATGLAVAGPGRFSVDHATDNRLNTPPVLLSAFAASALAATEVLRRRTKVMAAQAAAAGDEADAEDEADSGETDNATQAAHDAAADLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q554</accession>
    <name>C7Q554_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795551.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6993"/>
    <dbReference type="EnsemblBacteria" id="ACU75823">
        <property type="protein sequence ID" value="ACU75823"/>
        <property type="gene ID" value="Caci_6993"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6993"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092402_0_0_11"/>
    <dbReference type="OMA" id="FMEPAFK"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="9">
        <location>
            <begin position="24"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU75823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="28160" checksum="553E4417F2AA52A9" modified="2009-10-13" version="1">MSTATADTPSGPGAGSPLDAARRIGVLIRHQVIMRVRDPGQVISYVLTPMILMLVFKPLYLRAFAGNQGTLQVVTGPLIMFSVFTLAIIGNSILVEREWHTWDRLRTSSASVSEILLGKLIPVYLIVVFQQTLLMAYGCLIIGLPFPHSVGLVAIAICSWALALLALGAALATVLRSHAELGMVSDVGAITISALGGALVPVSIMPTWAAVAAHGSPGYWAIRMMQAAVRGDTGGTLRPAALLLGGAAAAGSFAVYRLARGWGRSHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q581</accession>
    <name>C7Q581_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase FGGY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795578.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7020"/>
    <dbReference type="EnsemblBacteria" id="ACU75850">
        <property type="protein sequence ID" value="ACU75850"/>
        <property type="gene ID" value="Caci_7020"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7020"/>
    <dbReference type="eggNOG" id="COG1070">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_12_0_11"/>
    <dbReference type="OrthoDB" id="1619686at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="323"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="540" mass="53526" checksum="B067D7D730E896D0" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Q1</accession>
    <name>C7Q5Q1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ParB-like partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_9049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797586.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9049"/>
    <dbReference type="EnsemblBacteria" id="ACU77862">
        <property type="protein sequence ID" value="ACU77862"/>
        <property type="gene ID" value="Caci_9049"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9049"/>
    <dbReference type="eggNOG" id="COG1475">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023853_7_2_11"/>
    <dbReference type="OMA" id="IALSYQR"/>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="117"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="398" mass="43529" checksum="D3B0A76D92594D10" modified="2009-10-13" version="1">MSSSRRGLGKGLGALIPTGAPPAILSEKTRAESASAPAAGDVSRETSIDVSRETSVATAPPRTALGSLPIETDYRTTEDRSDRAFSASIPAPSASRESFADESLPDGLMPVPGASFAEIPQGQIRPNPVQPRTEFDEVALAELVASIKEVGLLQPIVVRQLPEPDGEHRYELIMGERRWRASQEAGLSAIPAIIRDTRDDRMLLDALLENLQRAQLNPLEEAAAYDQLLKDFDCTHEVLAEKIGKSRPHVTNTLRLLTLTPGIQRRVAAGVITAGHARALLGLKSVEQQEEIAKRIVRENLSVRAVEELAGMGRWDAAALDTALTETPEDYLDFTDKPKNKRVRSGSRMPILEDFGQRLSDRLETRVKVDIMQKRGRITIEYAGIEDLKRIAKAILGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q662</accession>
    <name>C7Q662_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787361.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3159"/>
    <dbReference type="EnsemblBacteria" id="ACU72068">
        <property type="protein sequence ID" value="ACU72068"/>
        <property type="gene ID" value="Caci_3159"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3159"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043648_0_0_11"/>
    <dbReference type="OMA" id="RELHAHC"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014305">
        <property type="entry name" value="RNA_pol_sigma-G_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02960">
        <property type="entry name" value="SigX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="147"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="334" mass="36324" checksum="CAAC0804BC737D94" modified="2009-10-13" version="1">MATKAMTLTQRARSGDGAAFDELVAPYRRELQVHCYRMLGSFQDAEDALQDTLLSAWQGLSGFEERSSVRTWLYRIATNRCLNARRSASRRSAKEWNVPGVEPPAPTRLGEVFWLEPFPDALLEGVLDASPPGPEARYEQSEAISLAFVTALQVLPPRQVAVLLLRDVLGYHGAEVAEMLDTTAESVSSALKRARAGLERQRSASAPTSGSSEESALAAKFATAYEAADIETLIALLTDDVFTSMPPMPFEYQGRDATITFLTSILATGRRHRLIPTRANNQPAFGAYLRGTGATSHGVGLFVLETTTTGISAMTRFENGVLPWFGLPRSIPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6I4</accession>
    <name>C7Q6I4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="5">3.2.1.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 54 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5160"/>
    <dbReference type="CAZy" id="CBM42">
        <property type="family name" value="Carbohydrate-Binding Module Family 42"/>
    </dbReference>
    <dbReference type="CAZy" id="GH54">
        <property type="family name" value="Glycoside Hydrolase Family 54"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74019">
        <property type="protein sequence ID" value="ACU74019"/>
        <property type="gene ID" value="Caci_5160"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5160"/>
    <dbReference type="eggNOG" id="COG3250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5297">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029332_3_0_11"/>
    <dbReference type="OMA" id="HYNTACC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031221">
        <property type="term" value="P:arabinan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015289">
        <property type="entry name" value="A-L-arabinofuranosidase_B_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038964">
        <property type="entry name" value="ABFB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007934">
        <property type="entry name" value="AbfB_ABD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036195">
        <property type="entry name" value="AbfB_ABD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39447">
        <property type="entry name" value="PTHR39447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05270">
        <property type="entry name" value="AbfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09206">
        <property type="entry name" value="ArabFuran-catal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110221">
        <property type="entry name" value="SSF110221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980635" evidence="2">
        <location>
            <begin position="41"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="ArabFuran-catal" evidence="4">
        <location>
            <begin position="45"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="AbfB" evidence="3">
        <location>
            <begin position="371"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="519" mass="53749" checksum="12B0DA09232A692E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P2</accession>
    <name>C7Q6P2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic protein G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5218"/>
    <dbReference type="EnsemblBacteria" id="ACU74077">
        <property type="protein sequence ID" value="ACU74077"/>
        <property type="gene ID" value="Caci_5218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5218"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029872_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982576" evidence="1">
        <location>
            <begin position="27"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="211"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="542" mass="54918" checksum="707FD1654CDF87D1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q790</accession>
    <name>C7Q790_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1253"/>
    <dbReference type="EnsemblBacteria" id="ACU70178">
        <property type="protein sequence ID" value="ACU70178"/>
        <property type="gene ID" value="Caci_1253"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1253"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048109_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="131"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28729" checksum="BCDFBE601BA06D3F" modified="2009-10-13" version="1">MAIEPESRSDTITGGGGRRVGLQAIAATGWGFTERAYIGDWDLRASGGHTARANSALPIGDSGMPLSQTLHAVGEWYAERNLPAQIQTIDGSPLDEAIAGLGHWETHRPALRQSAPLSPVLEILRSSTDPLRVASITPELPEDYFTVYRRGYGIPEFRTILTSGDALIAFAVVRADNGDALCVGRLAIDTGTGYAGIAGLATADHARRRGLARIVMRDLLASAAEHGAENTYLEVDEENAPALALYAALGYATAHRYHSRRLSRQDVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7G3</accession>
    <name>C7Q7G3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1327"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH55">
        <property type="family name" value="Glycoside Hydrolase Family 55"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70251">
        <property type="protein sequence ID" value="ACU70251"/>
        <property type="gene ID" value="Caci_1327"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1327"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013797_0_0_11"/>
    <dbReference type="OMA" id="IDHTWAW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982880" evidence="1">
        <location>
            <begin position="38"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="44"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="732" mass="75962" checksum="5C4D127939BD29CA" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7J9</accession>
    <name>C7Q7J9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787485.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3285"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72192">
        <property type="protein sequence ID" value="ACU72192"/>
        <property type="gene ID" value="Caci_3285"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3285"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_10_1_11"/>
    <dbReference type="OMA" id="VVCTTEF"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="202"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="395" mass="42388" checksum="AB84F489242153CA" modified="2009-10-13" version="1">MRIVQLANAYTPNSGGLRTVVDELGRGYVAAGHERVLVIPGQRHSREEGESGLVVTLPSVPVSGGYRMIPRFSPVRELLEELQPDTVEVSDKATLAAAGPWARQRGVGAVLISHERLDAVAAARFPHAWRASHRALKPALHRRSRRLATRFDAVVVASAFAGTEFAGTSGFLREIPLGVDLDTFCPNRNERPVETEEPRGTGEHPWRLVYSGRLSVEKNPIAAIAAVRALISEDVPVHLDVYGTGSQRDHLERVAAELPITFHGYLADRAELAARIAEADVVIAPGPAETFGLTVLESLACGTPVVTADTGGAGELLAAGAGIAAASTGADMARAVAGILAWPEAERRAAARHRAEQFPWSATIASMLDVHAVLAARERSLNRLKRRGLRRRMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7X9</accession>
    <name>C7Q7X9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793875.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5287"/>
    <dbReference type="EnsemblBacteria" id="ACU74146">
        <property type="protein sequence ID" value="ACU74146"/>
        <property type="gene ID" value="Caci_5287"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5287"/>
    <dbReference type="HOGENOM" id="CLU_1438695_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="188" mass="21411" checksum="A80033F8862A2460" modified="2009-10-13" version="1">MQLLLLAVDPDRDGRTHFTAALAPALVLADLLDKTRRGRPAPDSMSDYLRVRAPSRLDRYIDAAKHEGILDVSVRRDGYFGHTRIRIADRWPLERAVDRLLRILDTPQHPHDRDLAYVILAHEIGRAHPHLKGRKHRDHRRRLDTLTTWPADHARRPSTPNAVLYAGLHAMRLTAGEQQQAAPLAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7Z4</accession>
    <name>C7Q7Z4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase-like_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793890.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5302"/>
    <dbReference type="EnsemblBacteria" id="ACU74161">
        <property type="protein sequence ID" value="ACU74161"/>
        <property type="gene ID" value="Caci_5302"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5302"/>
    <dbReference type="eggNOG" id="ENOG5030MQE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1297691_0_0_11"/>
    <dbReference type="OMA" id="GGGWMGW"/>
    <dbReference type="OrthoDB" id="1791609at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like_dom" evidence="1">
        <location>
            <begin position="3"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="214" mass="23054" checksum="7113E543EF30B880" modified="2009-10-13" version="1">MRLDHVSYAVSNSELGSTVNRLGTLLGATFRDGGVHPRFGTRNFVLPLAGGSYVEVVAPLDHPATDAAPFGKAVKARAEDGGGWLGWVVGVDDITPWEQRLGRPAAAGHRVRPDGFDLRWKQLGVLDLMADPQLPYFLAWEISADQRPGAGAVNGVPAFERLEISGDRTQVLSWIGGSPDHDPLEEVKVDWIDAEEPGVLAVHFRCAAGSVRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q837</accession>
    <name>C7Q837_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="12" type="ordered locus">Caci_5345</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793933.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5345"/>
    <dbReference type="EnsemblBacteria" id="ACU74204">
        <property type="protein sequence ID" value="ACU74204"/>
        <property type="gene ID" value="Caci_5345"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5345"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_1_1_11"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="1502854at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="11">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU74204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="204" mass="21852" checksum="95E9F7532740E872" modified="2009-10-13" version="1">MSDRAGTDGHGSDTSAPAPALLTVLSGPSGVGKTTLAKHVREAHPQVWLSVSATTRTPRPGEVDGVHYFFYDRPAFEDLIAEGAFLEHAEYAGNLYGTPRRAVEQRLEAGQPVLLEIELQGARQIRAAMPAARLVFLAPPSWEVLEQRLRGRGTEPEAVIAERLATGRVELAAESEFDVTIVNTTVEAAAEELVELVTGAGSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8F4</accession>
    <name>C7Q8F4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795870.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7313"/>
    <dbReference type="EnsemblBacteria" id="ACU76142">
        <property type="protein sequence ID" value="ACU76142"/>
        <property type="gene ID" value="Caci_7313"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7313"/>
    <dbReference type="eggNOG" id="ENOG502Z8JN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049028_1_0_11"/>
    <dbReference type="OMA" id="YARTSYY"/>
    <dbReference type="OrthoDB" id="687977at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="468" mass="51606" checksum="7A8D126BA0588E4B" modified="2009-10-13" version="1">MPYPNERASRLGHLPTAESPLIVEALSRWETPILGAEDSAAIADRCVALNDLKSDRQQGPSFVISFDGSDQEVEARRQYPSVRVGYIQIAGVLVRVDEFLNARVDGLVDARKVQRAQTRQTIQTVLPSSQVTRPQMSGVESWRVELYETFKRQAIADFGSPYSLVDALLRLHGRPGEPEADVRPELGRCPDCQASGQKVGTDPTTCSECGCALYPTDLLRTHEEYADEGSNVNILTRVMNVAERLLALSYIDNFARYAPTALGAGLFITDGPLAFFGPTAPLKRRMVEYWGRLCHWLAQQGHAVPLLVGIEKSGVFVDHAMAIASQIPPQHVMTLSNAYISEKIRRRPSAGTYGKDEFYGRRFFYKTSTDQMLVVTVPRVPAGQPYEQGPEGANPCEAIDSYPTLRATLEALDRFQTRLYPNAVIPLALAHSAASLPLGTGRDVLTLLAQRGLQLDRDSIGFGRTPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Z5</accession>
    <name>C7Q8Z5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787608.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72315">
        <property type="protein sequence ID" value="ACU72315"/>
        <property type="gene ID" value="Caci_3409"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3409"/>
    <dbReference type="HOGENOM" id="CLU_131335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11226" checksum="6BC16FA7A54386B8" modified="2009-10-13" version="1">MTDAIDTSALATKVFDAVKPAIGAYGTGALVRDEQANAPHAVELGREILQEIYWRDKNVPPLESAVNDFAAGSQDEDAAAGLRLEIKKVLASDAALAADIAKMVGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q966</accession>
    <name>C7Q966_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787679.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3480"/>
    <dbReference type="EnsemblBacteria" id="ACU72386">
        <property type="protein sequence ID" value="ACU72386"/>
        <property type="gene ID" value="Caci_3480"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3480"/>
    <dbReference type="eggNOG" id="COG3861">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324449_0_0_11"/>
    <dbReference type="OrthoDB" id="1779215at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="229" mass="24458" checksum="73393D15319C4967" modified="2009-10-13" version="1">MYDNLEYVMGSRVRCAGELCGHVESVVVDPVAGKLTHLVVIADEGDGDGEARLVPVHLAVPSTDSVDLNCTRERFEEFEPAVETRFLQGAVDPATGNGGDGRIWQWPYFGVALTPGPLGTAPAVDPEPPITTVERIPAGEVGVRRGERVHAVDGEIGRVRGLVVVPPDSEVTHVLLDEGHLWGRKRVAIPIRDVAGIDLEGVAVRLTKDEIKDLPPVDVAGLEDEGASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9C6</accession>
    <name>C7Q9C6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Virulence factor MVIN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_5413</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794001.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5413"/>
    <dbReference type="EnsemblBacteria" id="ACU74272">
        <property type="protein sequence ID" value="ACU74272"/>
        <property type="gene ID" value="Caci_5413"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5413"/>
    <dbReference type="eggNOG" id="COG0728">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006797_2_0_11"/>
    <dbReference type="OMA" id="WLYFANR"/>
    <dbReference type="OrthoDB" id="749401at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="648" mass="66164" checksum="061943EE3DD2571F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9R5</accession>
    <name>C7Q9R5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795962.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7408"/>
    <dbReference type="EnsemblBacteria" id="ACU76234">
        <property type="protein sequence ID" value="ACU76234"/>
        <property type="gene ID" value="Caci_7408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7408"/>
    <dbReference type="eggNOG" id="ENOG5031K3Y">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089257_0_0_11"/>
    <dbReference type="OMA" id="GDLMSNM"/>
    <dbReference type="OrthoDB" id="1522794at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025445">
        <property type="entry name" value="DUF4191"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13829">
        <property type="entry name" value="DUF4191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="242" mass="26390" checksum="6786E7F9D5A33D89" modified="2009-10-13" version="1">MARDTTTKTPAGGDAPKKKGRLTQIREVYGMTRKEDPKLPLVLAAWALGALVVFVALGVLLGSPLFYGIFGIPVAVLAAMIVFGRRAQRAAYSSIKDQAGAAASVLDTLRRGWDVTPGVRFNRQQDMIHRVLGRPGIILVGEGNPNRLKALFTEERRHLTRLFGPDVPLVAQDIVAGDEEGMVPLGRLNKTVMRLKPATGKGYLRPAQVQEYQNRLKAVGPNMPIPKGPMPRNGKMPRGQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9U5</accession>
    <name>C7Q9U5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795989.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7439"/>
    <dbReference type="EnsemblBacteria" id="ACU76264">
        <property type="protein sequence ID" value="ACU76264"/>
        <property type="gene ID" value="Caci_7439"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7439"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_100_0_11"/>
    <dbReference type="OMA" id="LHKARML"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009594">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06719">
        <property type="entry name" value="AraC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="189"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="291" mass="31708" checksum="14374705005501D3" modified="2009-10-13" version="1">MEPLDELASLVARHAHPDSRTAIDGLLLSRVETAEPEYSLTEPLLVLMVRGHKHLQLGDHVIDHRSGDALVVTTDLPVTGHFAGASISEPALGVGIALRPEPIAALLPQLPAGPWSRTRAEGPAMATGPADLELLDAVLRLVRLLDRPPDIAVLAPGLEREILWRLLTGRHAAAVAQIGRADSELAHLGRAIAWLRTNFAEPVRIAELASRAGMSQSAFHRRFRTVTGMSPLQFQKQLRLQEARTLLLARSGDATRVAHTVGYASASQFSREYRRLFGAPPLRDTVRLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9X5</accession>
    <name>C7Q9X5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796019.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7469"/>
    <dbReference type="EnsemblBacteria" id="ACU76294">
        <property type="protein sequence ID" value="ACU76294"/>
        <property type="gene ID" value="Caci_7469"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7469"/>
    <dbReference type="eggNOG" id="COG1432">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034061_0_0_11"/>
    <dbReference type="OMA" id="IDADNTQ"/>
    <dbReference type="OrthoDB" id="990092at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="176"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="260" mass="28293" checksum="E6ED74234D266784" modified="2009-10-13" version="1">MVAENPVKLAVLIDADNAQPSNAATLLAEIAKYGTAHVKRAYGDWTGTSLKGWKEHLLALSIQPIQQFAYTSGKNATDAAMVIDAMDLLYSGRFEGFCIVSSDSDFTRLAARIRESGLIVYGFGERKTPKPFVAACDKFVYTENLAFAEEGAFPDEIVPSTVEKPTAKIAATKLRGDAKLVNLLRNAVEAASDEDGWAGLSGVGHILTNQQPDFDSRTYGYPKLSNLVTATGLFDVDRRSTGEGKPAQIHIRDKRYESRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBV7</accession>
    <name>C7QBV7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3674"/>
    <dbReference type="EnsemblBacteria" id="ACU72576">
        <property type="protein sequence ID" value="ACU72576"/>
        <property type="gene ID" value="Caci_3674"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3674"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605053_0_0_11"/>
    <dbReference type="OMA" id="SVFLHER"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="15"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="452" mass="47165" checksum="9A01FF7A926A5EE3" modified="2009-10-13" version="1">MTGPWYRRLRELPLALRVLYLAMFVNRAGMFVFPLLAVYLVKGKHLGADQAGVLLSVGSTGLLVGSLLAGPLCLRWGCRWTLVGALLLNAAGYLGLAVADGGPWIYPAILFAALVGMGVFGPASNTLIADLAPPEQRAYAFTLSYMFNNLGMGVGPLLGGVAAAVSFSLMFAVNIAASLVVAGLLLLWVPVDRPASAGAAGVAGAGIGTQRPEKVGYRSLGHRHLWLLLGASFFYVVPLIGLEYSVPLAVTTSLNASTAYIGVVYTINSVVIVGFGLQVEKFIVRHSTRTLLLAAGALWSAGLVLPVVAFSLAALLLCTVIWTLGEIIVSVVVPAYIADQADERRVPGFMAVNGFVLGLARLVVPAGLGVLWSARGHAPVFGVLLAAPILGMAAFALLRLPHPSRQPEESDHDRDQVPASRGADPDHLVQRGAGPAGRVAADAAPGHQGADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCB3</accession>
    <name>C7QCB3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAGPA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5703"/>
    <dbReference type="EnsemblBacteria" id="ACU74561">
        <property type="protein sequence ID" value="ACU74561"/>
        <property type="gene ID" value="Caci_5703"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5703"/>
    <dbReference type="eggNOG" id="ENOG502ZCHD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_465968_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="NAGPA" evidence="3">
        <location>
            <begin position="402"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="585" mass="61938" checksum="411970B1BAAB1C08" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCR3</accession>
    <name>C7QCR3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polar amino acid ABC transporter, inner membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7702</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7702"/>
    <dbReference type="EnsemblBacteria" id="ACU76526">
        <property type="protein sequence ID" value="ACU76526"/>
        <property type="gene ID" value="Caci_7702"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7702"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_2_11"/>
    <dbReference type="OMA" id="VFEYINL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="81"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="333" mass="36808" checksum="83FE9B5BDEA0BBD2" modified="2009-10-13" version="1">MSENADPSEPYAADADTASAAAGTRPAAIRAVPVRRPGRWIAAAVLLVLLVMFGHMLVFNKNFGWDLVKQWLFWHTIVQAVLVTLELTVYAMLIGIVGGVLLAVMRLSSNPVSSSAAWAYTWFFRGTPVLVQLLFWNNIAALVGQEVGFGIPFGPEFFHLDTNSTITRFTAAVLALGLNEAAYMSEIVRAGILSVDEGQSEAAASLGMRRAKIMRRIVLPQAMRVIIPPTGNETISMLKTSSLASVIGVVELTDASESAIHLYFKAIPFYVVASLWYLFFTTVLSIGQYYIERRYARGSSRDLPPTPFQKLMKANLSLRRRRTSWTDTREALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD06</accession>
    <name>C7QD06_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transport/detoxification protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786010.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1795"/>
    <dbReference type="EnsemblBacteria" id="ACU70716">
        <property type="protein sequence ID" value="ACU70716"/>
        <property type="gene ID" value="Caci_1795"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1795"/>
    <dbReference type="eggNOG" id="COG2608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134973_13_1_11"/>
    <dbReference type="OMA" id="HCERTVS"/>
    <dbReference type="OrthoDB" id="2061355at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="75" mass="7285" checksum="07B47E129645178E" modified="2009-10-13" version="1">MTAVAETGTPAVAYGVLGMSCGHCSAAVTEALSALPGVAAVEIDLPGKRALVTSAAALEIAAVRDAVEGAGYQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QE50</accession>
    <name>C7QE50_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7814</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7814"/>
    <dbReference type="EnsemblBacteria" id="ACU76638">
        <property type="protein sequence ID" value="ACU76638"/>
        <property type="gene ID" value="Caci_7814"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7814"/>
    <dbReference type="eggNOG" id="COG0392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009723_0_0_11"/>
    <dbReference type="OMA" id="WRAVLWI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="687"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="741"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="821"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="854" mass="90636" checksum="987C43A7DCEEC2E5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEE1</accession>
    <name>C7QEE1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell envelope-related transcriptional attenuator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1912</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786125.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1912"/>
    <dbReference type="EnsemblBacteria" id="ACU70832">
        <property type="protein sequence ID" value="ACU70832"/>
        <property type="gene ID" value="Caci_1912"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1912"/>
    <dbReference type="eggNOG" id="COG1316">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016455_4_0_11"/>
    <dbReference type="OrthoDB" id="491753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="162"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="5">
        <location>
            <begin position="521"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="664" mass="69090" checksum="DD1D26BCDB1E9B54" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEE9</accession>
    <name>C7QEE9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative serine/threonine kinase anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786133.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1920"/>
    <dbReference type="EnsemblBacteria" id="ACU70840">
        <property type="protein sequence ID" value="ACU70840"/>
        <property type="gene ID" value="Caci_1920"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1920"/>
    <dbReference type="eggNOG" id="COG2172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116681_1_2_11"/>
    <dbReference type="OMA" id="LCEFREN"/>
    <dbReference type="OrthoDB" id="1832160at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="164" mass="16824" checksum="D327C2E578187306" modified="2009-10-13" version="1">MERVSGVGGEAGVGTGADGGGEGTDGRVPVTLSIPAERDYVVLVRSAAGHLGVRAGFSMAEMGDWRLAVDEACGLLLLPDEVDAIGEELDCVFRLSPAGLALTVSSEARPGSKPQVGGFGWSLLAALVDDLQWAEEAGRVRVDIVKRAAGGAPGPDRTARAEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEJ7</accession>
    <name>C7QEJ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M48 Ste24p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_1968</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1968"/>
    <dbReference type="EnsemblBacteria" id="ACU70888">
        <property type="protein sequence ID" value="ACU70888"/>
        <property type="gene ID" value="Caci_1968"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1968"/>
    <dbReference type="eggNOG" id="COG0501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="142"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU70888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="382" mass="38880" checksum="D82430E8C47A375B" modified="2009-10-13" version="1" precursor="true">MIAALILGSYALLLAVVGPGVVARVWPSGRMPRVTVVVLQVVSCSFLTAAATAGLALGLTLIDTLSRMDPQIDRCADQLPINDDSPVGPFLGWFGLVAGAALVVRVGFCLAATFLSAWWTRRKHIAILRICARADQELGVLVLEHDEPGCYCLPGRPGTIVITSSALTRLSPAQLGAVLAHERAHLTGRHHFAVAFAHAIHRTAPRIRLLGLVEQETRRLVEFIADDAAVRRSGTVALVSALAVLGAGSTAPGSAPGFALGVGMDRRPAASSRVTRLAHGQNGRRGLAMGAIGSALLIIVPLVLAALSVATVIHGCPPDKDGDADALALPPSVRLVGAAGAAESVGAVGSAGSVGSAGSVGSVASVFPGTSWDAAFGNSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEP4</accession>
    <name>C7QEP4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792543.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3930"/>
    <dbReference type="EnsemblBacteria" id="ACU72814">
        <property type="protein sequence ID" value="ACU72814"/>
        <property type="gene ID" value="Caci_3930"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3930"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061176_0_1_11"/>
    <dbReference type="OMA" id="TWFLGRA"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="36259" checksum="EB500B490A677622" modified="2009-10-13" version="1">MRILILGGTWFLGRAIAASAIEHGHQVTVFNRGRSGGDPDGAEAIRGDRESEDGLKRLAGSGPWDVVVDPSGQVPRVVLASARALVGSGRYVFVSSVSAYAGWPIDPLTETSALLESRADAGPEFGYTDPRGYPTQYGFAKAGCEQAVLDVFGPDRATILRPGVILGPWEYVGRLPWWLRRVAEGGRVLAPGDPNQLIQPVDVRDVADFATRTAEHDFGGAFNVTAPANHTTFAGFLEACRQVTGSDAEFVWVGDDQLAAVGVRQWTEIPLWRSVGAFPGTWKVSSAKAAASGLSARTIRATVADTWQWLTSGGQAVASARASELGIDPEREAEILACAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF12</accession>
    <name>C7QF12_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="6">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aspS</name>
        <name evidence="8" type="ordered locus">Caci_5912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794499.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5912"/>
    <dbReference type="EnsemblBacteria" id="ACU74770">
        <property type="protein sequence ID" value="ACU74770"/>
        <property type="gene ID" value="Caci_5912"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5912"/>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_1_11"/>
    <dbReference type="OMA" id="CKQHTVR"/>
    <dbReference type="OrthoDB" id="1138123at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="146"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="6">
        <location>
            <begin position="191"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="220"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="401"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="430" mass="47387" checksum="97105F6226623D93" modified="2009-10-13" version="1">MIHRVLASEMPAHVGETVQVCGWLHRRRELKNVTFLILRDRSGLTQAVLPGAVAEQLRDIPEETVLSFVGTVTANEQAPGGVEVVAPASGPQVELLSTPAETPPLDIYRPSVTASLPTILDGAPVALRHPLLNAPFQITAASIAGFRTALDALNFTEIHTPKIVGSATESGANVFALDWFGRKAYLAQSPQFFKQAMVGVFERVYETGPVFRAEPSDTARHLAQYTSLDAELGFITDHRDVMAVVREALAGMVTTVAERAPAAVDLLGVKLPTVPDQIPEIHFADAMKMLGEDEPDLSPANERDLSHWALREFGSEFLFVTGYPMTKRPFYTHAQPDRPNYSNSFDLIFRGLELITGGQRLHRYEDYIAALTARGEPTNAYEGYLANFKHGMPPHGGFALGLERWTMRLTEADNLRRTALFPRDLHRLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF13</accession>
    <name>C7QF13_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5913"/>
    <dbReference type="MEROPS" id="M24.033"/>
    <dbReference type="EnsemblBacteria" id="ACU74771">
        <property type="protein sequence ID" value="ACU74771"/>
        <property type="gene ID" value="Caci_5913"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5913"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_0_11"/>
    <dbReference type="OMA" id="AHACVLH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="3">
        <location>
            <begin position="42"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="51988" checksum="A1F1A597B725E527" modified="2009-10-13" version="1">MSSDPNLSKFATGSHDLPVTDALAAFMATQWAPSPLPDLAPTPVSAWTGHRRAAVSARFPGERLIVPAGVEKLRSNDTYWHYRPHSAFAHLTGGQLLEAVLVFEPNGTGHDAILFAHDRSSRDNGEAFRDRRLGEMWEGRRPSLSESSELYAIATENLNRLADKLSGAAVPTRVLRGSDPRVDSLVTARPEADAEFTAFLSELRLVKDAWEVEQLQAAVDATTLGFQDVARILPTVIGKPRGERWVEGAFNTRARIEGNDVGYNTIVGGGAHACVLHWTANNGTLNPGELLLLDAGVEVDSLYTADITRTLPISGTFTPLQRDLYNLVLSAQNAGIATLHAGANFRDFHWAAMRTIATGLIDMGILKVSLQEAMDPNVGLYRRYTLCGSGHMLGIDVHDCAKARAEEYVDGTLTAGNVLTVEPGLYLQPDDLTLPQELRGIGIRIEDDLLITDEGAILMSAALPREADEIEAWMAHQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF38</accession>
    <name>C7QF38_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase class 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794525.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5938"/>
    <dbReference type="EnsemblBacteria" id="ACU74796">
        <property type="protein sequence ID" value="ACU74796"/>
        <property type="gene ID" value="Caci_5938"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5938"/>
    <dbReference type="eggNOG" id="COG1075">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029537_1_2_11"/>
    <dbReference type="OMA" id="DLCPLDL"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002918">
        <property type="entry name" value="Lipase_EstA/Esterase_EstB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32015">
        <property type="entry name" value="PTHR32015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01674">
        <property type="entry name" value="Lipase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982803" evidence="1">
        <location>
            <begin position="29"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="283" mass="29673" checksum="911FC315B68658E8" modified="2009-10-13" version="1" precursor="true">MRKRRILHALSALLLVAPLVALAAPAQAATSSGINDFSCKPSAAHPRPVVLVHGTFGNASDNWLVGAPYIAARGYCVFELDYGQEPGIPLFHGLAPVAQSAQQLSDYVNQVLGATGASQVDIVGHSQGGMMPRYYLKFLGDAAKVHTLVGLAPSNHGTNLDDIETLAADYFPAALGLIGTACPSCSDQIVGSPLMQQLNAGGDTVPGVQYTVISTLFDEVVTPWQSQRLSGANVHNILLQNLCPTDLSEHVLIGTTDKIALHEAVNALDPSHATPTTCLSAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFF1</accession>
    <name>C7QFF1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7905"/>
    <dbReference type="EnsemblBacteria" id="ACU76728">
        <property type="protein sequence ID" value="ACU76728"/>
        <property type="gene ID" value="Caci_7905"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7905"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="RSIPTEM"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="110"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="336" mass="36923" checksum="CFE72F34725A44B9" modified="2009-10-13" version="1">MSATESTSVAAGRAATGTGPGPERGPGSAGSAGRRPVTGRPRFSKAHMKEWAWGYAMIGPLFLGLAIFYLWPIVQSAYFSFTSWGVFGGQQWVGFKNYSSFMSDPQLPRAVWNTVKYSLIILAGIPLSIVFAALMNQVSGKYASLYRVLYFIPVVTMPAAVAMIWRWLYNGDYGLINYLLSLIGIHGPHWVSDDRYTVWAMGLVGIWSSLGYNMIIFAAGLKNIPRQYYEASSLEGAGRIRQFFSITLPLLSPSIFFVSVLSVISGLQMFDMVLLMLGKSNPALAGSKTIAYLFYEDAFVTGNQGLAAAIAVVLTLVLLLLTALQFRLQKRWVHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFT7</accession>
    <name>C7QFT7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1994"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM35">
        <property type="family name" value="Carbohydrate-Binding Module Family 35"/>
    </dbReference>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70914">
        <property type="protein sequence ID" value="ACU70914"/>
        <property type="gene ID" value="Caci_1994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1994"/>
    <dbReference type="eggNOG" id="COG1501">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008391_0_0_11"/>
    <dbReference type="OMA" id="VQLRYAN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CMB_fam6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM6" evidence="5">
        <location>
            <begin position="166"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="940"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="4">
        <location>
            <begin position="1090"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU70914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1207" mass="126552" checksum="FD60828E87DF441E" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG48</accession>
    <name>C7QG48_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PknH_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792622.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4025"/>
    <dbReference type="EnsemblBacteria" id="ACU72893">
        <property type="protein sequence ID" value="ACU72893"/>
        <property type="gene ID" value="Caci_4025"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4025"/>
    <dbReference type="HOGENOM" id="CLU_1080497_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026954">
        <property type="entry name" value="PknH-like_Extracell"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14032">
        <property type="entry name" value="PknH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983195" description="PknH_C domain-containing protein" evidence="1">
        <location>
            <begin position="36"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PknH_C" evidence="2">
        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="24595" checksum="2F21DB9AF63C551D" modified="2009-10-13" version="1" precursor="true">MHIGIKYVSAVAVTAAAVLVVTACGGSGKSNGHSAAALTDDQVESLLLTDKDQPGYNFDASEDVRSTTDTPALVTTGDSACQSFRDAENALSTKYGTTVDLRRVLNSAHGVTMIQDAVEVMPSADKASALMADLTAGLKGCKTFTETEENEPTPTTLTAIPQMVGDDRVGYVTRASVQSDTEVDTTYVVRVGPVVVLMLETGTVNLGIVPLPQASETLLRLSDLQVARLKSAAGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA9</accession>
    <name>C7QGA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792683.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4089"/>
    <dbReference type="EnsemblBacteria" id="ACU72954">
        <property type="protein sequence ID" value="ACU72954"/>
        <property type="gene ID" value="Caci_4089"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4089"/>
    <dbReference type="eggNOG" id="ENOG50343Y4">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1109842_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983112" evidence="2">
        <location>
            <begin position="29"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="250" mass="24725" checksum="8BA529927F6AFE4F" modified="2009-10-13" version="1" precursor="true">MIRRTTLGTTAAAVATAGLLAASLSACGSDHRPAPAGRPSHASAPATGTPSTASTPSGPTGPALRAVLPTKADLAAGINVSGVYDTGTQFTAETDLPAPSLPTADCTAAPAIDADVLTGDYRAAYASEELDNAGNSLQLVVAATNPGDAAKQLAEIRAFANRCASFAAPDSAGLSVGGTVALDSFAGIGDEAIRIRVAAAGPDAAKYSQPEVLLVRVGDTIAAVSDADQTRNEAATVSAARLLADRLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGB8</accession>
    <name>C7QGB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4099</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4099"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72963">
        <property type="protein sequence ID" value="ACU72963"/>
        <property type="gene ID" value="Caci_4099"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4099"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983200" evidence="2">
        <location>
            <begin position="38"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="808"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="952"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU72963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1072" mass="108077" checksum="B58DD90FB6632EF6" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGG5</accession>
    <name>C7QGG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4146"/>
    <dbReference type="EnsemblBacteria" id="ACU73010">
        <property type="protein sequence ID" value="ACU73010"/>
        <property type="gene ID" value="Caci_4146"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4146"/>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010686_18_18_11"/>
    <dbReference type="OMA" id="WVEEISA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="457" mass="49788" checksum="BE161E8DF0825B85" modified="2009-10-13" version="1">MAVLDEADAVGALYCCVPRRGDEDQTPVDVQERQGRKYAAGIGITVPAHLVFADQRRSVWNPGSVRPGWSALLTAVRSGRVPAVVVIKPAMLVRHRSADAVELLIAAQEHGVELYSMGDALDLSDPEGRETALSQARQHAGKAASLSKTVQKLRRQNADDGRPHGGGRRAYGYGPGMRPLIIDEAETVREMYARYLAGESLRAIAGDLNTRGIPTVTGAKWTTGGVSRILVAPRYAGLRVFQGGVESIDGLRQAVWEPCVDIEDWRRAQAERAARSAATDHRPRADYLLTGLVVCERCRDHMVGSIVGDYRMYACPSKNKPLPDRCNRYIAAKSLEDHVQQAAVDLLENTGTTPAPSDLPVTVRRGPVGTPGHPDRFRTGHGRVETQSANVLEGVITGPEAPAAWQRLPEPRRRALLRYLFASIEIGAKTTSRSVFDTSRIKILPGVPLNERLVEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGH2</accession>
    <name>C7QGH2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5994"/>
    <dbReference type="EnsemblBacteria" id="ACU74852">
        <property type="protein sequence ID" value="ACU74852"/>
        <property type="gene ID" value="Caci_5994"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5994"/>
    <dbReference type="eggNOG" id="ENOG5032W34">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134416_1_0_11"/>
    <dbReference type="OMA" id="WLTLPDI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041098">
        <property type="entry name" value="Rv2175c_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18367">
        <property type="entry name" value="Rv2175c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rv2175c_C" evidence="1">
        <location>
            <begin position="85"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="140" mass="15402" checksum="4F69E02C4CE23712" modified="2009-10-13" version="1">MLGGVTEKNAAVGTAHAEAHRDSIDPETDALVGDWLTLPDVAERFGVQVTRVRQLLRDNQLIAVRRGENNALHVPAGFIVEDHSVKGLTGTLTLLKDAKFTDEEALRWLFTPDDSLPGTPVQALRENRGTEVRRRAQAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ0</accession>
    <name>C7QGJ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6013"/>
    <dbReference type="EnsemblBacteria" id="ACU74870">
        <property type="protein sequence ID" value="ACU74870"/>
        <property type="gene ID" value="Caci_6013"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6013"/>
    <dbReference type="eggNOG" id="COG3214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047003_0_1_11"/>
    <dbReference type="OMA" id="IQCYDEY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009351">
        <property type="entry name" value="YcaQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06224">
        <property type="entry name" value="HTH_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="342" mass="36693" checksum="42637122D59B8206" modified="2009-10-13" version="1">MRWLRVRAQGLAGDADAARRTVPDAVRAAAAVQAQAAGPARLQIWSRTHGLRAADVDTAVAEAAVVRTWLMRGTIHLVAADDLRPFLAVVGPVNLRADRRRREQLGLTDELCARAMDALPKILAGDRALTRAEIVAELAGHGIAVELKSQQPPHLLAFAANSALICRGPDAARDEPTYVLLDRWLKSETESPDRDTALTRLATRYFAAYAPATTADFAAWSGLSAADAKAAVALVRDTLEEADHDGLRLLLPRGIEPAPPERPQRLLARFDPYLLGHRSRDLILDPAFAKRVNAGGGMIAATMLDAGRVVGTWKQGSLEPFEALPGAAAKAWQPDLDAAAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGJ2</accession>
    <name>C7QGJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74872">
        <property type="protein sequence ID" value="ACU74872"/>
        <property type="gene ID" value="Caci_6015"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6015"/>
    <dbReference type="HOGENOM" id="CLU_004137_7_8_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983215" evidence="1">
        <location>
            <begin position="27"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="33" mass="3363" checksum="6A16F72A77090EC2" modified="2009-10-13" version="1" precursor="true">MAMAMAMAMAMAMAMAMAMAMAMAMAAQRSAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGX9</accession>
    <name>C7QGX9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796554.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8006"/>
    <dbReference type="EnsemblBacteria" id="ACU76829">
        <property type="protein sequence ID" value="ACU76829"/>
        <property type="gene ID" value="Caci_8006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8006"/>
    <dbReference type="eggNOG" id="COG1765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114057_0_1_11"/>
    <dbReference type="OMA" id="DCTVSRT"/>
    <dbReference type="OrthoDB" id="1430018at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14527" checksum="EAB210788A16FDDB" modified="2009-10-13" version="1">MYEIKVERTGDGRYIATNERGARIELSGDGQGPNFSPVELLLIAVAGCNIVTTEPLTAQRGHRMTTLAATATSEKVERNKLGPVTLSYSVELPEGDADAAKVFRDVAERVEERHCTVSRSLREGTPVNLDLDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGZ5</accession>
    <name>C7QGZ5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796570.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8022"/>
    <dbReference type="EnsemblBacteria" id="ACU76845">
        <property type="protein sequence ID" value="ACU76845"/>
        <property type="gene ID" value="Caci_8022"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8022"/>
    <dbReference type="eggNOG" id="COG0711">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735511_0_0_11"/>
    <dbReference type="OrthoDB" id="1602369at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="405" mass="45814" checksum="BAA81F96D714036B" modified="2009-10-13" version="1">MATSDRLEQMVGDLVQIVETAKAVPMSASCVINRAEVLEILHELAAGVSEELAESRRLVAEREEVIAQARRDASEHIEAARRERGSMLSGTEVGREAERIRGAALEEARRIREDADNYVDDKLANFEVVLTKTLQAVGRGRAKMVGRDPMSELGEHMAEQDAVEAATRPEYDFDERDEVPTGSAYQREPGYNTGEYPKYTDEAYETQQNGYQQEPSYQPAEPVYQEQPAYQEAAYPEPAYQEQPAYAPEPVYAQQGAGYAQSEYGQSEYGLPEPELSHEFAAADMSGVFQRPDFSQDYPPQEYQHQQQPAQVAVGYGYDQENGYAANYSDPASVPYPVQPYGTQYEQQQQPEYHSGEYQAYPQHEQQQQQYAQQPSHQQHPEASGFFDTGMIDVRQFRDDPYQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHB1</accession>
    <name>C7QHB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784345.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0095"/>
    <dbReference type="EnsemblBacteria" id="ACU69050">
        <property type="protein sequence ID" value="ACU69050"/>
        <property type="gene ID" value="Caci_0095"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0095"/>
    <dbReference type="eggNOG" id="COG3226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_21_0_11"/>
    <dbReference type="OMA" id="SNHARTR"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041583">
        <property type="entry name" value="TetR_C_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17940">
        <property type="entry name" value="TetR_C_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TetR_C_31" evidence="1">
        <location>
            <begin position="82"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="198" mass="21261" checksum="043ADB8839B2938A" modified="2009-10-13" version="1">MTSRPDLIGDTAIALLAERGLRGLTHRAVDEAAGLPPGSTSNHARTRSALLETTFARLCRLEAEIFEDAANPGGLLALATLTPETAADLVAAQLHDTLTHRREQALARFELALEATRRPELRAIYDTAGATFREPARGLMAALGATDPDRAGRSFIAFSEGILFDSVAGAGSRKVPTQEEIRDDLLELFRGMLMEPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHQ7</accession>
    <name>C7QHQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2012-07" db="PDB data bank">
            <title>von Willebrand factor type A from Catenulispora acidiphila.</title>
            <authorList>
                <consortium name="Midwest Center for Structural Genomics (MCSG)"/>
                <person name="Filippova E.V."/>
                <person name="Minasov G."/>
                <person name="Shuvalova L."/>
                <person name="Kiryukhina O."/>
                <person name="Jedrzejczak R."/>
                <person name="Joachimiak A."/>
                <person name="Anderson W.F."/>
            </authorList>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS)</scope>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786375.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="PDB" id="4FX5">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.73 A"/>
        <property type="chains" value="A=1-440"/>
    </dbReference>
    <dbReference type="PDBsum" id="4FX5"/>
    <dbReference type="SMR" id="C7QHQ7"/>
    <dbReference type="STRING" id="479433.Caci_2163"/>
    <dbReference type="EnsemblBacteria" id="ACU71082">
        <property type="protein sequence ID" value="ACU71082"/>
        <property type="gene ID" value="Caci_2163"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2163"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_564765_0_0_11"/>
    <dbReference type="OMA" id="YPTGSWG"/>
    <dbReference type="OrthoDB" id="692608at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041176">
        <property type="entry name" value="VWA_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18571">
        <property type="entry name" value="VWA_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4" id="KW-0002">3D-structure</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="57"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="4FX5"/>
        </source>
    </evidence>
    <sequence length="440" mass="46401" checksum="3D619364EE9039E5" modified="2009-10-13" version="1">MSQYPDFAFEINQNEFLAAGVREVHAVVTLTATAAAGGAPAAASYGAPASGSENVEVIIIDCSGSMDYPRTKMMAAKEATKVAIDTLTDGAFFAVVAGTEGARVVYPTGGQLLRADYQSRAAAKEAVGRLHANGGTAMGRWLAQAGRIFDTAPSAIKHAILLTDGKDESETPADLARAIQSSIGNFTADCRGIGEDWEPKELRKIADALLGTVGIIRDPATLAEDFREMTAKSMGKEVADVALRLWAPKGATIRYVKQVSPNLADLSGMRVPGDNPLTGDYPTGAWGAESREYHICVEVEPGNIGQEKLAGRVQLVAKDAGGATLLGEGKIRAVWTEDTDLSTRINGRVAHYTGQAEMAAAIQEGLDAQAAGDLDTATARLGRAMDLAVESGHEDTVKMLRKVTEVDPATSKVRAKAKVDKGDAMELDVVSTKTVRAKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHU4</accession>
    <name>C7QHU4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2200"/>
    <dbReference type="EnsemblBacteria" id="ACU71119">
        <property type="protein sequence ID" value="ACU71119"/>
        <property type="gene ID" value="Caci_2200"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2200"/>
    <dbReference type="HOGENOM" id="CLU_2407867_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="9102" checksum="726963B9E53FF36B" modified="2009-10-13" version="1">MVGLLDGFGDVGVVGCVDGFVEGFVVGLVLGAEVECGAEDELDVLDELDAAELLGAAAEVLVGTDVGVGAGALEEDEVELDAEEVFAATAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI00</accession>
    <name>C7QI00_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4181"/>
    <dbReference type="EnsemblBacteria" id="ACU73045">
        <property type="protein sequence ID" value="ACU73045"/>
        <property type="gene ID" value="Caci_4181"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4181"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_2_1_11"/>
    <dbReference type="OMA" id="ITFRMQQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14447" checksum="A6DAA6C867C24CD9" modified="2009-10-13" version="1">MSTTAPPADGNNKLTWMLDSLDIEGVRYSVLISGDGLRMAHSDSITRDEADAFAAAVSGVQSLGKALAVMCGDEDNRLRQNLIEYDQALVLVTAAGQNAMLGVCAEPTADAGLIVHRMNDLASRLGNELTSETRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI49</accession>
    <name>C7QI49_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792823.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4230"/>
    <dbReference type="ESTHER" id="catad-c7qi49">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73094">
        <property type="protein sequence ID" value="ACU73094"/>
        <property type="gene ID" value="Caci_4230"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4230"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_3_1_11"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26868" checksum="DD62B9A39BA6A813" modified="2009-10-13" version="1">MNRIPVVLIHGVGVDMSSWEGWTERFAAHGYDVHVPAEPSGVFGLEELTAHYEKAVRSQDRPPVLIGHSVGGLIARQLLDAGLGRAAVAIAPLPLPLPLAPPSSDKAGTQSEDYTQLLQPLFRHTIANAVGEEEAAQLYARYVVPAPRRLLVDLGLDDTMRSGGDVAAGEGVVVDAATRGPLLLISGQEDRMVADAVTRATYKLYGDSTAVTDLKQFADRGHSLVFDSGWPAVADYVLAWLAANGITSPAEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI75</accession>
    <name>C7QI75_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">o-succinylbenzoate synthase</fullName>
            <shortName evidence="3">OSB synthase</shortName>
            <shortName evidence="3">OSBS</shortName>
            <ecNumber evidence="2 3">4.2.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">4-(2'-carboxyphenyl)-4-oxybutyric acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">o-succinylbenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menC</name>
        <name evidence="5" type="ordered locus">Caci_4256</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10196"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18325"/>
            <dbReference type="ChEBI" id="CHEBI:58689"/>
            <dbReference type="EC" id="4.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.113" evidence="2 3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4256"/>
    <dbReference type="EnsemblBacteria" id="ACU73120">
        <property type="protein sequence ID" value="ACU73120"/>
        <property type="gene ID" value="Caci_4256"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4256"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_4_11"/>
    <dbReference type="OMA" id="CRIINIK"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043748">
        <property type="term" value="F:O-succinylbenzoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03317">
        <property type="entry name" value="NAAAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01933">
        <property type="entry name" value="MenC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010197">
        <property type="entry name" value="OSB_synthase_MenC_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48073:SF5">
        <property type="entry name" value="PTHR48073:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01928">
        <property type="entry name" value="menC_lowGC/arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="4">
        <location>
            <begin position="142"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="39515" checksum="7DC9E427CACE38E2" modified="2009-10-13" version="1">MKISGVELRRLTMPLRSPFETSFGVATERDILLVRVATEEADGWGECVAMNDPLYSSEYTQGAHDVITRYFLPKLAAAPRVTAALVAQILAPFKGHPIAKAAVESAVLDAELRAVGTSFGDHLGAVRTSVPVGVSVGIMPSVAELIDTVGGYLDQGYRRVKLKIKPGWDVEPVRAVRERFGDELLLQVDANTAYTLGDAQRLAALDPFDLLLIEQPLPEDDLRGHAALSRLVKTPICLDESIVSARSAADAIALDACRIVNIKPARVGGYLEARRVHDVCAAHGVPVWCGGMLETGIGRAANVALAALPNFTLPGDISASERYFTRDITEPFVLRDGGLDVPQGPGLGVTPDPALLEEFTTAKHWFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI76</accession>
    <name>C7QI76_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792850.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4257"/>
    <dbReference type="EnsemblBacteria" id="ACU73121">
        <property type="protein sequence ID" value="ACU73121"/>
        <property type="gene ID" value="Caci_4257"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4257"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_13_0_11"/>
    <dbReference type="OMA" id="DMGRWMQ"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="464" mass="49207" checksum="BB3DD4725E978990" modified="2009-10-13" version="1">MTDLNGLLPDLIALLDTATRENHVPGAAVAVSAGDQVIELATGVLNLNTGVTATPDSLFQIGSITKTLTATLTMQLVDAGLVDLDEPVRTYVPELAVSDREAAETVTVRQLLSHTSGLPGDVFTDFGRGDDAVLRYVEGLKDHEQMYEPGRMYSYCNAGYSVLGLMVQRIRELPSWEAVLREHLIAPLGLTHVAALAEEALLFRTAVGHLDDGKKVAPIWQLPRSAAPAGASTCARARDLLTFARMHMNGGLAQDGTRILSEESVAAMREQQVALPGSGNLLGTGWGLGFGLIDRPGGRVVGHNGGTIGQSSQMRFVPDEGVAFAVLTNGGDALPVFQAVERHVFGTLTGIEPQSPDTPPHSAVPVDAKSFLGSYANAGQRVDITQHDDGSLHATLTPQGALVALSGPDPEHKPLVGYTPVSLLDAEPERGMYMEYVIAEADERGRATHLLLGGRVHTRLSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI98</accession>
    <name>C7QI98_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794704.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6121"/>
    <dbReference type="EnsemblBacteria" id="ACU74975">
        <property type="protein sequence ID" value="ACU74975"/>
        <property type="gene ID" value="Caci_6121"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6121"/>
    <dbReference type="eggNOG" id="ENOG5032GRJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051661_2_1_11"/>
    <dbReference type="OMA" id="FPARVAI"/>
    <dbReference type="OrthoDB" id="2055578at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017517">
        <property type="entry name" value="CHP03083_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017520">
        <property type="entry name" value="CHP03086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03083">
        <property type="entry name" value="TIGR03083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03086">
        <property type="entry name" value="TIGR03086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="202" mass="22062" checksum="C904E3E0FA5BFB4C" modified="2009-10-13" version="1">MTDIRDLNARAVRDSMDVVRQVQVTDLGRPTPCEGWTLADLLGHMAVQHRGFAAAARGDGAEMRHWEFVSAGADAVQQYLAASEDVLAAYAELGDDLEGAVFELPEFSVDPPRFPARLGIGFHFIDYVVHAWDVAVTIGIDFELRPELEQDALRITLAVPNGDNRTADGSAFVSALEIPEDASTLDKILLYLGRTPGWRPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QII6</accession>
    <name>C7QII6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794792.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6209"/>
    <dbReference type="EnsemblBacteria" id="ACU75063">
        <property type="protein sequence ID" value="ACU75063"/>
        <property type="gene ID" value="Caci_6209"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6209"/>
    <dbReference type="eggNOG" id="COG3324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1164902_0_0_11"/>
    <dbReference type="OMA" id="IRWTYAF"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="135"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="244" mass="26869" checksum="6D65FFF90CA56D44" modified="2009-10-13" version="1">MLKWAWAFIDRPERVFEESARFWTAVTGTTLSARRGERGEFATLVPADRDADASLKLQGVLSGNGAHIDLEFDDFEKAVARAVDLGGTVVERDEVWAHVTSPSGYGLCVAAWNGARQVARPYVAPDGTRTRLDQVCIDIAPSALDTEVAFWGGVSGLRVVPSSRWAEFSWLEPVHGSPVEVLFQRIDEERPTSAHLDVSSTDADASRRRHESLGAEFVREGANWLVMRDPGGGTYCLIRREPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ27</accession>
    <name>C7QJ27_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784464.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0214"/>
    <dbReference type="EnsemblBacteria" id="ACU69169">
        <property type="protein sequence ID" value="ACU69169"/>
        <property type="gene ID" value="Caci_0214"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0214"/>
    <dbReference type="eggNOG" id="COG1225">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102256_0_0_11"/>
    <dbReference type="OMA" id="FCYPRTG"/>
    <dbReference type="OrthoDB" id="1748122at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="20907" checksum="8173FE297AB371B2" modified="2009-10-13" version="1">MHDIYTLPADLPIPQDDGAADHLPGARVPELTLTSTAGEAIALAALGEGRTVLYIYPLSGRPGEEAPEGWSAIPGARGCTTEACDFRDHHKELLEAGAARVFGLSSQDSAYQQELVERLRLPFAMLSDTGLRLAAELDLPTFEAGGRLLYKRITLVIRDGVIEHAFYPIFPPDRHAGEVLGWLTKNPVRRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ61</accession>
    <name>C7QJ61_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hutI</name>
        <name evidence="6" type="ordered locus">Caci_0250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0250"/>
    <dbReference type="EnsemblBacteria" id="ACU69203">
        <property type="protein sequence ID" value="ACU69203"/>
        <property type="gene ID" value="Caci_0250"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0250"/>
    <dbReference type="eggNOG" id="COG1228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041647_1_0_11"/>
    <dbReference type="OMA" id="CAPHARW"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01296">
        <property type="entry name" value="Imidazolone-5PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="65"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="393" mass="41140" checksum="5688E06A8A294D7A" modified="2009-10-13" version="1">MGSSVTSTLLTGIAELTTHADSGGLADSTVADAAMVVVDGRVAWTGPGAGAPDADERVELGGRAVIPGFVDSHAHLVFAGDRAQEFAARMTGAPYSAGGIRTTVAATRGASDDVLRSNLRRLVGEMLRQGTTTVECKSGYGLTVEDEARALRLAREQVEAVTYLGAHVVPAEYKDRAGEYVDLVKGPMLDACAPYADFADVFCERGAFDEEQTREILTAARAKGLDLRLHANQLGNGPGVQLAVEFGAASADHCTFLDDKDIDALAGSQTIATLLPGVEFSTRSPYPDARRLLDAGATVAIATDCNPGSCYTNSMPFCIAVAVRDMHMSPAEALWAATVGGAKALRRDDVGHLGVGARADFAVLDAPSYLHLAYRPGVPLVHRVWKNGTPVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJG9</accession>
    <name>C7QJG9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2274"/>
    <dbReference type="EnsemblBacteria" id="ACU71192">
        <property type="protein sequence ID" value="ACU71192"/>
        <property type="gene ID" value="Caci_2274"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2274"/>
    <dbReference type="eggNOG" id="ENOG50339I2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_646704_0_0_11"/>
    <dbReference type="OMA" id="FAYLWTA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="46910" checksum="59314EC931DDE7D2" modified="2009-10-13" version="1">MDTLRRLALRARGDVPVTAWLILLAVFVTEYWWWHSRVKLWDGDALYYVAAALKFAGHSTDDSLRLTGVFFHQEATVGRIRGTLTGVAGQPGVGEFNLEAPRFFYSALAVPFVWVFGAKGIWVVSYLCAAVFLFVTMRLLTRLFGVQLALAMLVLYQIAYAFWFFQTGIYTESLAALLIVLIITRLPLERETSRRDLIWIGVLLLVLAFTRQTVPVPVAAIVFAYLWTAIRTKTWGKANVWNRPALVAGGIGVFAVGLVTALFPFNELRHYSEVNHLGNTAYVKAHLGQTLGKIPGLVVDMFAREFRGAFAGDHGLQVLWLLTAVAIVWRFRNVYAAMVVGAALACAVLSILDATGRTSLRYFVPMYPLALMLVADFWRSREWSVRTLPSRPGLGSAGSEPPAPQPAARHTDAPPLPAAEPSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJJ2</accession>
    <name>C7QJJ2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2297"/>
    <dbReference type="EnsemblBacteria" id="ACU71215">
        <property type="protein sequence ID" value="ACU71215"/>
        <property type="gene ID" value="Caci_2297"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2297"/>
    <dbReference type="eggNOG" id="ENOG5032YQ8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182353_1_0_11"/>
    <dbReference type="OMA" id="WEASPHH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="10782" checksum="262135B7775E1D0C" modified="2009-10-13" version="1">MAVRRRVLVSAGTCSAKLFYGGFVTSDDSPATALCSAKGCRTPAAWSVVWNNPKLHTPDRRKVWLACDEHRQHLADFLDVRGFLIEVEPFRPGTPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJJ8</accession>
    <name>C7QJJ8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_2303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2303"/>
    <dbReference type="EnsemblBacteria" id="ACU71221">
        <property type="protein sequence ID" value="ACU71221"/>
        <property type="gene ID" value="Caci_2303"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2303"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="45"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU71221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="518" mass="55050" checksum="BB8A328B3DF0D820" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK0</accession>
    <name>C7QJK0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2305"/>
    <dbReference type="EnsemblBacteria" id="ACU71223">
        <property type="protein sequence ID" value="ACU71223"/>
        <property type="gene ID" value="Caci_2305"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2305"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4978">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065103_2_2_11"/>
    <dbReference type="OMA" id="SMESDGP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="268" mass="29632" checksum="B82D8BFB2B91AABB" modified="2009-10-13" version="1">MLTSGEFSRRARLSPKALRLYDQQGLLVPDEVDAVSRYRRYRVGRLADARLIVWLRRLDMPLADVARVLAAPAAEREALVAAYWEAAEAKFAAQRWLAARVREEVSGHEGAHRMTQEILTRDVPAQLVLTEQRHVTPEELPGWIGQAMMRLLAAADPVGGPAADPFVVYHGEINHDSDGPAEVCVPVDPARAAALTAPTREEPAHREAYLRITKAQVEFPQILSAYDAVSRWLTAAGHTAALPPREVYFTDWDAAGPDDDVCDIAFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJM0</accession>
    <name>C7QJM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA/rRNA methyltransferase (SpoU)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786536.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2325"/>
    <dbReference type="EnsemblBacteria" id="ACU71243">
        <property type="protein sequence ID" value="ACU71243"/>
        <property type="gene ID" value="Caci_2325"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2325"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_3_11"/>
    <dbReference type="OMA" id="GYHVHRG"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="121"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="269" mass="28358" checksum="28BCDF522EDD8A96" modified="2009-10-13" version="1">MGELIEVTDPSDPRLHDYSGLTDVELRKVREPAEGLFLAEGEKVIRRALAAGYPMRSTLLSPKWAQAMRPLIEEVDAPVYVGSEALLEAVTGFHVHRGALASMQRTPVSEAGAVLAAAKRVVVMEDIVNHTNLGAIFRSAAALGMDAAVLTPSCADPLYRRSVRVSMGTVFALPYARLDSWPGGLTTLAEHGFRTIALTPGPTAIDLRDLRFGPEDKVALLLGTEGDGLSDPALAAADMRVRIPMTAGVDSLNVAAAAAVACYAIAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX1</accession>
    <name>C7QJX1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792938.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4345"/>
    <dbReference type="EnsemblBacteria" id="ACU73209">
        <property type="protein sequence ID" value="ACU73209"/>
        <property type="gene ID" value="Caci_4345"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4345"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_1_11"/>
    <dbReference type="OMA" id="VQWPEQG"/>
    <dbReference type="OrthoDB" id="1469807at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="116"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="415" mass="45535" checksum="A03F40A9E4C0A4A9" modified="2009-10-13" version="1">MRSDQRLEDLLAELRPAVLGALVRRHGQFDGCEDAVQEALVAAATQWPAEGVPDNPRAWLLTVAGRRLTDYWRSDHARRTREATVAAMAAPESAYAPAPDDEERISADDDTLMLLFLCCHPVLSPSSQVALTLRAVGGLTTEEIAQAFLVPQTSMTRRISRAKQQVKDAGLTFRLPPQAERAERTRAVLHVLYLIFNEGYTATAGPDLLRPDLTAEAIRLTRQVHRVLPENGEVEGLLALMLLTEARSPARTLADGTLVPMADQDRSLWNGDLAEEGLALVVEALARPGVGPYRLQAAIAAVHVETPADGTTDWPQILALYDLLEQMAPNAVVRLNRAVAMAMVEGAREGLRLLEPLEQDRWMAGNHRLSAVRAYLLEMDGDRAGAREAYRTAARQAASGPEQRYLREQAERLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJY1</accession>
    <name>C7QJY1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792948.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4355"/>
    <dbReference type="EnsemblBacteria" id="ACU73219">
        <property type="protein sequence ID" value="ACU73219"/>
        <property type="gene ID" value="Caci_4355"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4355"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="EYPMVDR"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="421" mass="45181" checksum="96EB2AEA33D98136" modified="2009-10-13" version="1" precursor="true">MRILIVGAGIGGLSTALSLHAAWVGADIRVIDSVSELRPLGVGINLLPHATRELIELGLGPELARMAVPTAEVIVMDRFGNRIWSEARGRGAGYNWPQYSVHRGELQTMLAEAVRDRLGAGSVQTSTSLAELRQNGDRVLSRLVGRDGRDMGTVESDIVIGADGLHSTVRAQLHPEEGAARWSGVMMWRGCVEGEAFLGGKTMMWAGSNRAAKFVVYPVSPPRGESGRVLINWVAEVRVDDAAAQPPDWNRAGDLADVLPHFEGWTMAGVDVCGLMAATPKVLEYPMVDRDPLPFWGRGRVTLVGDAAHPMYPIGSNGGSQAILDARHLAHLLAQHEGDPGAGLAAYEEVRRPATAAVVAANRRFPMDRILNVVAERAPEGFGEIGEVLSEAEIKEIDEAFRSTTGFDADALNARASLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB8</accession>
    <name>C7PVB8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fatty acid hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784569.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0321"/>
    <dbReference type="EnsemblBacteria" id="ACU69274">
        <property type="protein sequence ID" value="ACU69274"/>
        <property type="gene ID" value="Caci_0321"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0321"/>
    <dbReference type="eggNOG" id="COG3000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033631_1_0_11"/>
    <dbReference type="OMA" id="RFWWATH"/>
    <dbReference type="OrthoDB" id="2048011at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="88"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="32467" checksum="DA08A1BECC2E0694" modified="2009-10-13" version="1">MRLVIDGIDLTTLAIPFYVLFMALELLSLRFFPDPVEQGYTVKDTATSLTMGIGSIVCNLGWGLVTVAAVAGVHALAPWHIASSLTGWLVLFVAYDFFYYWEHRANHRVRILWASHVVHHSSRHYNLSTALRQTWTGVGNTIFLLPLALVGFPSYMIFATAAMNLLYQFWIHTERIATMWRPIEFVMNTPSHHRVHHGSNQGYLDKNYGGVFIVFDRLFRSFEPEGEPVEYGLTKNIGTFNPLRVAAHEYAAIARDVRGAAGWRARFGYVLRGPGWSPASPVPATAVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVP0</accession>
    <name>C7PVP0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786575.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2364"/>
    <dbReference type="EnsemblBacteria" id="ACU71282">
        <property type="protein sequence ID" value="ACU71282"/>
        <property type="gene ID" value="Caci_2364"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2364"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_5_0_11"/>
    <dbReference type="OMA" id="GAWGTNC"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="231" mass="24349" checksum="FAC1C7FBE9ED3901" modified="2009-10-13" version="1">MLVAGFPAGSLGANCYLVAPAAGEQCVIIDPGEDAVPGVEDAVREHGLQPVAILLTHGHVDHTMSVVPVCGDYGVPAYIHPGDREMLTDPQKWLGIAPGTKVFGQSKFVEPSDVKELTDGVVLNLAGLEITVDHTPGHTKGSVTFRTPEQQDIPQVLYTGDLLFAGAVGRWDLPGGDRDELLASLARVCLPLPDETVVLSGHGPQTTIGRERATNPFLTEAAPLSVKPRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVR0</accession>
    <name>C7PVR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786595.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2384"/>
    <dbReference type="EnsemblBacteria" id="ACU71302">
        <property type="protein sequence ID" value="ACU71302"/>
        <property type="gene ID" value="Caci_2384"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2384"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023778_0_0_11"/>
    <dbReference type="OMA" id="EVEITWT"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="604" mass="59303" checksum="DA4F7AEDCE92E08F" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWA9</accession>
    <name>C7PWA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4494"/>
    <dbReference type="EnsemblBacteria" id="ACU73357">
        <property type="protein sequence ID" value="ACU73357"/>
        <property type="gene ID" value="Caci_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4494"/>
    <dbReference type="eggNOG" id="COG1129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_11"/>
    <dbReference type="OMA" id="FNARILI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="316" mass="34026" checksum="A14C3AEED544264B" modified="2009-10-13" version="1">MTTLLEADGVGKYFGNVRALSGVSLSVRAGQVTCVLGDNGAGKSTLIKILSGVFTPDEGEVRIDGAAVKFHSPRDARAAGIATVFQDLAMVPLMAIWRNFYLGSEPTKGWGPWRRFDARAARASTREALSAMGIDLRDPDQPVGTLSGGERQSVAIARAVHFGARVLILDEPTSALGVKQAGVVLRRVVQARERGLGVVFITHNPHHAHPVGDRFVVLNRGRLLGDFAKNEISRDELVRLMAGGAELETLGHELERIPGIEVEPEPELESDPEQESESKPDMHAQDSQEELDGHRSHQPHDPQAGPAPAEALDEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWD2</accession>
    <name>C7PWD2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="3">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="3">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">murQ</name>
        <name evidence="6" type="ordered locus">Caci_4517</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793109.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4517"/>
    <dbReference type="EnsemblBacteria" id="ACU73380">
        <property type="protein sequence ID" value="ACU73380"/>
        <property type="gene ID" value="Caci_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4517"/>
    <dbReference type="eggNOG" id="COG2103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049049_1_1_11"/>
    <dbReference type="OMA" id="CPPTFCT"/>
    <dbReference type="OrthoDB" id="1100044at2"/>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005486">
        <property type="entry name" value="Glucokinase_regulatory_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01272">
        <property type="entry name" value="GCKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="63"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="307" mass="30621" checksum="0826CF4E90820538" modified="2009-10-13" version="1">MSPLTPPTAERVAAPTEERNPATADIDAVPTAEVLRLLNAEDARVPAAVAAVLPALAEVVDETVRRLRAGGRVHYFGAGTSGRVAVMDAAELIPTFGLPAGVVVAHIAGGLGALTIPVEGAEDSAEGGAADAAEVTAADVVIGLTASGRAPYVAGALRAAREAGAFTALISANPHAALAHEADVHLGPDTGPEAVAGSTRLKAATAQKLILNGLSTAAMIALGHTYSNLMVDLAPTNTKLRGRVLTILTEATGLPEDACAAALAEADGELKTALVCLLGAVAPDDARRALTAADGQVRAALAASART</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWI2</accession>
    <name>C7PWI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794991.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6408"/>
    <dbReference type="EnsemblBacteria" id="ACU75262">
        <property type="protein sequence ID" value="ACU75262"/>
        <property type="gene ID" value="Caci_6408"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6408"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_254785_0_0_11"/>
    <dbReference type="OrthoDB" id="1832114at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002160">
        <property type="entry name" value="Prot_inh_Kunz-lg"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00283">
        <property type="entry name" value="SOYBEAN_KUNITZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982625" evidence="1">
        <location>
            <begin position="38"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1375" mass="137734" checksum="8A30654C4482A4C9" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWJ9</accession>
    <name>C7PWJ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaK</name>
        <name evidence="9" type="ordered locus">Caci_6427</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795008.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6427"/>
    <dbReference type="EnsemblBacteria" id="ACU75279">
        <property type="protein sequence ID" value="ACU75279"/>
        <property type="gene ID" value="Caci_6427"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6427"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_2_1_11"/>
    <dbReference type="OMA" id="AYTKNQD"/>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="592"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU75279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="636" mass="67821" checksum="565FC21B1424BD6B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWP5</accession>
    <name>C7PWP5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795054.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6475"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75325">
        <property type="protein sequence ID" value="ACU75325"/>
        <property type="gene ID" value="Caci_6475"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6475"/>
    <dbReference type="eggNOG" id="COG1472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095794_2_0_11"/>
    <dbReference type="OMA" id="THCLDVP"/>
    <dbReference type="OrthoDB" id="2045755at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980414" evidence="1">
        <location>
            <begin position="30"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="31"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="186" mass="19539" checksum="08CDBBA746C4F00A" modified="2009-10-13" version="1" precursor="true">MKRLRNAIFAAGFAAVASGVFGAATVAHASTSGPLTISNFGTNQCLQPVGESTAAGAAIVQEPCDGSPAQTWFEYPVGGTIGHYKNSYSGLCLDARGSAVNGTPVQQWVCNGISNENWEYPDVPSDDVPPLISRVSGTSTHCLDVPGAQNTPGLAMQIYRCNGSEAQLWWQWPPTPPSINLEKGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>C7PX68</accession>
    <name>C7PX68_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_0467</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784714.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0467"/>
    <dbReference type="EnsemblBacteria" id="ACU69419">
        <property type="protein sequence ID" value="ACU69419"/>
        <property type="gene ID" value="Caci_0467"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0467"/>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="METIFLA"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="185"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="246"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU69419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="451" mass="47126" checksum="47665FD8942C6590" modified="2009-10-13" version="1" precursor="true">MNLRTRLAVAGGSIVAGALVLVSVVLYPAVDTSLRGQIDKALATAAAQAPDVAAYIKSQNAPPDGQTPAAPLFPPISMGIGTTKLQIIPSDVVRIGPSAQFIDVSAHDVSVALGGTGPYFQDATYNGVAYRVYTMPFPDSRGSLVRTAIPESDPAPTLHELAWLLAASTVAAGLLAALAARLAARRVLRPVGRLTETVELIRATGDLTIPIPAASRDEIGRLGAAFSAMTSALDESVGAQRRLVADASHELRTPLTSLTVNLELLAENPSDAQAPLLAAEALGQAGELKALVNDLVDLARFGQAAFHTEDVRLDLVAERVAARAARRAPRIDFELRCAPTWVHGDPDALERAFANLVDNAVKWSPAGGRVRISVVKGVVEIADDGPGIPDSDLDFVFDRFYRSPAARAHPGSGLGLAIVRQVAETHGGTARAVRCSTGALLRLTLPVSGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXA9</accession>
    <name>C7PXA9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784755.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0514"/>
    <dbReference type="EnsemblBacteria" id="ACU69460">
        <property type="protein sequence ID" value="ACU69460"/>
        <property type="gene ID" value="Caci_0514"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0514"/>
    <dbReference type="eggNOG" id="ENOG5032R1N">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050216_0_0_11"/>
    <dbReference type="OMA" id="ASEMCGK"/>
    <dbReference type="OrthoDB" id="864839at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026367">
        <property type="entry name" value="FxsC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04276">
        <property type="entry name" value="FxsC_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="454" mass="50756" checksum="FA2007E197F2CFAA" modified="2009-10-13" version="1">MSPSGPGEAESPRYSEYGSCFFLSYAHTPRVFDDGPDLNYWVRQFFRDLCNELVSCDPTTWHRPTGPPGFMDDAIPEGALWRRVLARELATCRVFVPLYHRSYFSSVNCGKEWAVFRARQMAQLAQTGVPNEAILPVVWKPPRSEDLPEFASALQMSRLSVSDAYFERGLYELIRLDRDREYTNVVLRFAEWLDETARTCAPPLGPLADYELVRPLFPTDDSGKGADRRFRITVAAPDEKSAPPGRSRDYYGPQPEDWRPYYPDSTVPLARRAEDVARGLGYTPVVSALTRHSPEMRPRPRNPAAGAGAIPDAPGVLLVDPWIAHTPDSGSVAEVDRCHKDWIRVLVPWSGTDRQTAEQAATLRSLLEGVMPWSMEEWHRTASAATRELASVADFGHAMPDVMERAWRRYLRAVRPAGSGGREFPSRPRLRDGPDADADADGDAGASTDDGTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXB4</accession>
    <name>C7PXB4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0521"/>
    <dbReference type="EnsemblBacteria" id="ACU69465">
        <property type="protein sequence ID" value="ACU69465"/>
        <property type="gene ID" value="Caci_0521"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0521"/>
    <dbReference type="eggNOG" id="COG1487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181601_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="92" mass="10131" checksum="E9D061A61827C7B2" modified="2009-10-13" version="1">MLQAVQSTADGMRVSTLLNSLFGWVPCPDDPWQQVIGIQHDLIKIGHDRGPGAIDILVALTAVQHRLTVLHLDNDFAAIAKVRPDIQVQQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXC4</accession>
    <name>C7PXC4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA synthetase class II (G H P and S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784770.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0532"/>
    <dbReference type="EnsemblBacteria" id="ACU69475">
        <property type="protein sequence ID" value="ACU69475"/>
        <property type="gene ID" value="Caci_0532"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0532"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054340_1_0_11"/>
    <dbReference type="OMA" id="NTHRNFF"/>
    <dbReference type="OrthoDB" id="596492at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30885" checksum="F663C25858B58CFE" modified="2009-10-13" version="1">MANKTESAGTDRGLAVLRARDLELRDAIDAVVLSWAAEAGAARTAYPPLLRTSDLAALDYWVNFPHLALLAVGADAGREKELAAADHSVIAPELLAPAEYALPSAACYSAYLDLSGTRLDGAHKITTVATCFRRENHFEGLRRLLSFTMREVVCVGNREAVLEHASSFKKRVGEFARRLGLPLEVQAATDPFFEKDAARTLMQQLFPVKEEFVFGGGLAIASVNFHRNFFGERCDIRLADGSPAFTSCVAFGLERWLAALTERFGRDDPALPERIAEAARWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL5</accession>
    <name>C7PXL5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786761.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2550"/>
    <dbReference type="EnsemblBacteria" id="ACU71468">
        <property type="protein sequence ID" value="ACU71468"/>
        <property type="gene ID" value="Caci_2550"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2550"/>
    <dbReference type="eggNOG" id="COG4129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037626_1_0_11"/>
    <dbReference type="OMA" id="TLEICTV"/>
    <dbReference type="OrthoDB" id="1936155at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010343">
        <property type="entry name" value="ArAE_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06081">
        <property type="entry name" value="ArAE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980433" evidence="3">
        <location>
            <begin position="29"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="46551" checksum="FB0C18CA03E8E8B6" modified="2009-10-13" version="1" precursor="true">MPRVPDLRSASSASSASSASSASSASSAASAWAARLPRYRNDPVVMWTIRATTAAVLAFAVATWLSSEPAPLTAPLTALLVVQVTLYATLTTGIRRVVSVVAGVLIAVGFSAVVGLSWWSLGLIILAALTIGQFIHVGEFVNEVAISAMLVLGVTQLASQAWERVLETLIGAGVGLLFNIVLAPPVWVDPAAESIVGLARRTRNLLLSIGEELDTPLPVHQAANRLHEARRLDQAVADVDAALRQAEESLRLNPRISEGLLARLVLRTGLDTLEICVVVVRVLARSLTDLAKQREEAEPLFPAETAQALQELLADIGAALVSYAVLVTTPLSDSAEQAENRLASELSAAWDLRQPVAEMLLHSVQQHPHAWQLHGSLLAEIDRMLDEMDLEHRSQRLMQELDRAAAARHERSARFATLKRLARMEWLPGRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXL8</accession>
    <name>C7PXL8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2553"/>
    <dbReference type="EnsemblBacteria" id="ACU71471">
        <property type="protein sequence ID" value="ACU71471"/>
        <property type="gene ID" value="Caci_2553"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2553"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_4_11"/>
    <dbReference type="OMA" id="DLCCRIR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="40204" checksum="5FE1CF7B6ED094F0" modified="2009-10-13" version="1" precursor="true">MSPNRSPQPLAATPAATAVLAMVLTEGPLSRVDLARRLGISSAAVTKAARPFLDDGYLHELDSERTAPGAGRPVSPLAITPDREFVIGVKVTADEVIGVVADLKARIRNSAHRQLPDCEPATVLATLAALVEELLDADPELRGKTRRMGVAVSGDVDRVRGVVRLSPLLGWQDVDLAGPVGDATGLVVVVENDVKALTVAEHWFGDGVGTDDFTLVTVGAGIGCGIVTGGRLLSGAYGVAGEVGHVCVDASGPVCHCGARGCVEAIAATEAIVGRARLLTGRDGLTFTEAAELARSGSPEVCALFSEAGTAIGLAITAVVNLIGPERIVVSGEGLDAYDLFETEIRQAYATHAFGAAARCPLTIRPLPFEEWARGAAAVGIQTLFAPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXU5</accession>
    <name>C7PXU5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4542"/>
    <dbReference type="EnsemblBacteria" id="ACU73405">
        <property type="protein sequence ID" value="ACU73405"/>
        <property type="gene ID" value="Caci_4542"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4542"/>
    <dbReference type="eggNOG" id="ENOG5032T1U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159912_0_0_11"/>
    <dbReference type="OMA" id="WRRAPFV"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="106" mass="11038" checksum="CC2B1710E35C551B" modified="2009-10-13" version="1" precursor="true">MKSSLPLVLAAMSTLAIGTFAFRLVGPMLHARITFSSRAQRLLETSAVVLLAALVLLSGLTEGRSFADLARPLGVAAGGVLAWRKAPFLVVVLTAAAVAALVRLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY02</accession>
    <name>C7PY02_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793191.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4600"/>
    <dbReference type="EnsemblBacteria" id="ACU73462">
        <property type="protein sequence ID" value="ACU73462"/>
        <property type="gene ID" value="Caci_4600"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4600"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077964_0_1_11"/>
    <dbReference type="OMA" id="VAFARIC"/>
    <dbReference type="OrthoDB" id="1948031at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="248" mass="26548" checksum="AF0C083F13579C48" modified="2009-10-13" version="1">MNATRPVAAEIPLYAGTDLASIARLFADTTRATFCLALLDNRAWTPTELARHAGVALSTATEHLNALVAGGLLTEERQGRHRYVHLANPHIADLIETLAAAAPLHPSPAPRTLSADTRRRALAHARTCYDHLAGTLGVAITNAMTDHALIDWQQGLRLTPTGEKWLSDQGIKVAATGRRPALRPCLDWTERRPHLAGTIPAALCDHALAHGWIKRIGSTRAVIVTPAGRDVLGERLGLSAEILTPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYK2</accession>
    <name>C7PYK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797049.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8501"/>
    <dbReference type="EnsemblBacteria" id="ACU77324">
        <property type="protein sequence ID" value="ACU77324"/>
        <property type="gene ID" value="Caci_8501"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8501"/>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_10_2_11"/>
    <dbReference type="OMA" id="VDHTYLF"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="13"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="358" mass="37823" checksum="6E42BA9BBA750337" modified="2009-10-13" version="1">MSGGSPAAEQPGIAVVGAGYWGPNLVRNLMGSPDWDLRWLVDLDTERARKVAAPYASVQVTSALDEALADPRVKAVAIATPARTHRDVAMAALRAGRHVLVEKPLAATEAEGAELVAEAAKRGLILMCDHTYCYTPAALAIRELIHSGELGEVHFVDSVRINLGLIQPDVDVLWDLAPHDLSILDFILPDTVKPVAVAATGADPLGAGRTCVAYLTLALSSGAIAHGHVNWLSPTKVRTITVGGSKRTLVWDDVNPAQRVSVFDRGVDLARPEELGADQRRAALVSYRTGDMVAPALNEREALAAAVEEFARAVRTGTPAATDGRAGLRVLRILEAASRSLAENGALVAVNDDALEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYM0</accession>
    <name>C7PYM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_8519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797067.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8519"/>
    <dbReference type="EnsemblBacteria" id="ACU77342">
        <property type="protein sequence ID" value="ACU77342"/>
        <property type="gene ID" value="Caci_8519"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8519"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_383897_0_0_11"/>
    <dbReference type="OMA" id="IMHAPRE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="15"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="609"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="311"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="720" mass="73551" checksum="086FBC51017BAA8C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYQ4</accession>
    <name>C7PYQ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797101.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8556"/>
    <dbReference type="EnsemblBacteria" id="ACU77376">
        <property type="protein sequence ID" value="ACU77376"/>
        <property type="gene ID" value="Caci_8556"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8556"/>
    <dbReference type="HOGENOM" id="CLU_2421568_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="91" mass="10118" checksum="4EEDF3D59BDD85DE" modified="2009-10-13" version="1">MATASDRQHNPEPVTVRVEISQVSKLIEEATYLIHTNTAPVSALLAFHERKARLFEALAAEEPENADRQEVAKNARAQVDHLNAMAERGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYY3</accession>
    <name>C7PYY3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69539">
        <property type="protein sequence ID" value="ACU69539"/>
        <property type="gene ID" value="Caci_0603"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0603"/>
    <dbReference type="HOGENOM" id="CLU_1871676_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14806" checksum="5103A815F0DE99A2" modified="2009-10-13" version="1">MQVMAARGWRLAARAAQARVMASRTRWLRVRTLVLALRDRLALAGQMRAMAASCGRLPVRRTQALAVRARVIAARTRRLQVRALVLAARRTLVLAARARVVAASGWLLLARARVVAASGWLLLARARALAVLAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ80</accession>
    <name>C7PZ80_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786830.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2620"/>
    <dbReference type="EnsemblBacteria" id="ACU71537">
        <property type="protein sequence ID" value="ACU71537"/>
        <property type="gene ID" value="Caci_2620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2620"/>
    <dbReference type="eggNOG" id="COG1940">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="OMA" id="DNDVNWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="379" mass="38925" checksum="E45DC45F18CA779C" modified="2009-10-13" version="1">MPLERPELPDSARAVFRALAVDGPASRPALSEALGISKVTMSAAIGELESLGLVRSQGMTRGATGRSAVLYTLAPGAGHVLGVEVGATRVRVAAHSLDGLRISTRTEALASHHRQVTTDATAVAIALVETVRAEVGEDYGPLRGVVIAAPTLPKAGPAGRQLLDGVQLLTTELPVPPEVPMSVENNVNCAAVAEHRIGVARDYGTFAYLQIGVKIGVGLIIDGALLRGTHGAAGEVAMVPFPWAPGVRPRRAGLEEYLGSDALMERCAAAWPTGGTPVPKDAVALFDAAAGGDAHARRVVDEHARDIGALVVSVLAVFDPGLIVLGGGVGQNQLVLPEVRRTVQALAWDTEVTAGALGDHATLLGAVHTAIGRALDAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZE3</accession>
    <name>C7PZE3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786893.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2684"/>
    <dbReference type="EnsemblBacteria" id="ACU71600">
        <property type="protein sequence ID" value="ACU71600"/>
        <property type="gene ID" value="Caci_2684"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2684"/>
    <dbReference type="HOGENOM" id="CLU_2599570_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="8605" checksum="1074E7E034FC9A6C" modified="2009-10-13" version="1">MSLENGSVRAEQVTAGMDILCRGAWRPVLADVDIVAARNGRRARITVGRAQADTTDVIDLVAHSVVRVRVRTKPLQVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZH9</accession>
    <name>C7PZH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MbtH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2721"/>
    <dbReference type="EnsemblBacteria" id="ACU71636">
        <property type="protein sequence ID" value="ACU71636"/>
        <property type="gene ID" value="Caci_2721"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2721"/>
    <dbReference type="eggNOG" id="COG3251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2245068_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005153">
        <property type="entry name" value="MbtH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038020">
        <property type="entry name" value="MbtH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03621">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00923">
        <property type="entry name" value="MbtH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160582">
        <property type="entry name" value="SSF160582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MbtH" evidence="2">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="104" mass="10260" checksum="B4560D6D91DFD121" modified="2009-10-13" version="1">MNVLDDEAAPFLVLGNAAQEYSLWPAAGDVPVPGGWRAVFGPAERHACLAEIGRVWVDRAGAESAGGESSGTGSAGGESAGTESTGTESARAQSTAATGSGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZT8</accession>
    <name>C7PZT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793332.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4742"/>
    <dbReference type="EnsemblBacteria" id="ACU73603">
        <property type="protein sequence ID" value="ACU73603"/>
        <property type="gene ID" value="Caci_4742"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4742"/>
    <dbReference type="eggNOG" id="COG4325">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137915_0_0_11"/>
    <dbReference type="OMA" id="FHHYNIG"/>
    <dbReference type="OrthoDB" id="1487105at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="16779" checksum="87059380A3442A56" modified="2009-10-13" version="1">MARIRRLRDVHPTRRGLVLAWWSFTVMFGGLRLLTWAIHVHVAGLGNVSAGGVHIHHYLWGILILIGVGAAGVVERSPRWHAWLGLLFGIGLALVVDEAALLIELKDVYWTGNGGVSIAIAVIIIGLAGSVLALTRAPGLDEEQENQKWDAGAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q153</accession>
    <name>C7Q153_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787021.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71728">
        <property type="protein sequence ID" value="ACU71728"/>
        <property type="gene ID" value="Caci_2819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2819"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1313574_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="209" mass="22438" checksum="D3370E904CDE24D4" modified="2009-10-13" version="1">MSHLLGHLRDAGLIVRNRGTLRGAHTRYSATELGTGLVGALRPVTDWAVADFGFVVAATRVRLGLAPLDGLVPTSRCQERSATNMAINLLAGLWTNVLMVYVDSAGEGGIGPQSLEEAVNGDIKASSGEGRVVRPLPHGTMHATLKALVARGLLLRVEYPPQVRYSLSTHGRGLMDAWWQVADTWGIANDNKLFRIVAKTSGWFQSAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1A0</accession>
    <name>C7Q1A0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2866"/>
    <dbReference type="EnsemblBacteria" id="ACU71775">
        <property type="protein sequence ID" value="ACU71775"/>
        <property type="gene ID" value="Caci_2866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2866"/>
    <dbReference type="HOGENOM" id="CLU_3005701_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="56" mass="6541" checksum="2EB211C0D989E143" modified="2009-10-13" version="1">MTDHCACLVFLTPDAVGRIERYESCPQHWRLFDDEFEIPRESAPVDLDEFLDLIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1G2</accession>
    <name>C7Q1G2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73691">
        <property type="protein sequence ID" value="ACU73691"/>
        <property type="gene ID" value="Caci_4830"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4830"/>
    <dbReference type="HOGENOM" id="CLU_2286408_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="101" mass="11030" checksum="5CE141A6E058FB26" modified="2009-10-13" version="1">MYDVLDHAGFLIDEERGLTIESLSETVRVRCRSDYSLLRPAIDLATVRQRETSHGYGNGIQAAVTTAIAAVLEQAGYSVQARDCEIFVTASAAVRQRPSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1H3</accession>
    <name>C7Q1H3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793431.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4841"/>
    <dbReference type="EnsemblBacteria" id="ACU73702">
        <property type="protein sequence ID" value="ACU73702"/>
        <property type="gene ID" value="Caci_4841"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4841"/>
    <dbReference type="HOGENOM" id="CLU_2218329_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="11661" checksum="AECB6D562BDFD214" modified="2009-10-13" version="1">MFDSSRDCTSVEKGVLTRLIAAALVNETVAWLDAETQAENEVASLWGRRTPDEHRLPVKVTTRMLVQLAAAADTAVSTRHGYGAGSGWTVQVGRDLAEIRKLIGAVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1J7</accession>
    <name>C7Q1J7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793455.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4866"/>
    <dbReference type="EnsemblBacteria" id="ACU73726">
        <property type="protein sequence ID" value="ACU73726"/>
        <property type="gene ID" value="Caci_4866"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4866"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_4_0_11"/>
    <dbReference type="OMA" id="DHYHPWN"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019945">
        <property type="entry name" value="F420_G6P_DH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03557">
        <property type="entry name" value="F420_G6P_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="324" mass="35305" checksum="77BB909C11B18C4C" modified="2009-10-13" version="1">MTSFGYFLSCEEFTPAELIEQAKLAQEAGFTHLAISDHFHPWTDAQGNSPFVWSMIGALSQVTSLPITTLVTCPTVRIHPAVVAQAAATSSVLTSGRFRLGVGTGEALNEHILGDRWPPFEERAEMLEEAVGIMRRLFTGGQVSHRGRHYTVEDARLYTAPTADLPIHVSGFGPKAAELAGRIGDGYVTMTPDTDLIEVFREASGGSKPVIGGVKVCWDTDRDRAVKTVRRLWSSELLPGELAQVLPTPAHFEQANTLVTEKQVAENTACGDDAAAHVEAVAAYVKAGFDEVYIGQIGQNHRGFFDFYAKQILPRLNDLHASQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1K2</accession>
    <name>C7Q1K2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793460.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4871"/>
    <dbReference type="EnsemblBacteria" id="ACU73731">
        <property type="protein sequence ID" value="ACU73731"/>
        <property type="gene ID" value="Caci_4871"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4871"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032284_1_0_11"/>
    <dbReference type="OrthoDB" id="1046754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="46"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="477" mass="52573" checksum="474A4FAC805D8D55" modified="2009-10-13" version="1">MPNLSASAREIPVPFEGKGSGVCAMTWGQQAIWDTIARTGRTLNIGGVMAMPEGTPVEEIAGVLRFAMSRHQSLRARLRLDDIDDRGLPRQQVFESGQTALVVLDVSDADDPATAAEELRMRYEMTPFDYEHEWPVRMAVVCRGGKVSHLVVQYCHLAVDGGGIDALIRDLEHLDPETGAATAPVQGAELLTLAESQASASGRRRSDKALRFWEKGLRSIPAQRFNGSDDPREDRFWEMYCYSPAMFLALQSIAARTKAETTHVALAAFAVSLARVTGRSPSVTQVLVNNRFRPDFADAVMQVSQSGLCVVDVADCTFDEVVGRAWKAATAAYLHGYFDETARTRLFDQVDEERGEHVDVSCFVNDRRGQSGPQPGDPLPTPEELAAALHRTRMRWDRRMPMYDTTMFLHLDAAPDANVPGRTDPHESELPAVYFQLWADTHKIAPADIERFARGLEGVLVEAAFDGTVPTRVAAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1X9</accession>
    <name>C7Q1X9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6839"/>
    <dbReference type="EnsemblBacteria" id="ACU75680">
        <property type="protein sequence ID" value="ACU75680"/>
        <property type="gene ID" value="Caci_6839"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6839"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_11"/>
    <dbReference type="OMA" id="NMVERTV"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="25782" checksum="E95A31B5587AE1A7" modified="2009-10-13" version="1">MMNDVADSTDVAGTVALVTGGSRGIGAAIARKLASHGAAVALTYVQAAEQAKEVVAQIEAGGGRAIAIQADLTLPDAAVQAVEQTVRDLGGLDILVNNAGFLTYGPLDEVTETELDRVLAVDVRSVFLASQAAARHMREGGRVISIGSCFNGHVPAENFVLQAMAKSALVGLTKGLARELGSRGITATVVDPGPIDTDMNPEDGDSADFQRSLTALGRYGAAEDIANAVAYLAGPGGRYITGTALAVDGGYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J3</accession>
    <name>C7Q2J3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_0903</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0903"/>
    <dbReference type="EnsemblBacteria" id="ACU69835">
        <property type="protein sequence ID" value="ACU69835"/>
        <property type="gene ID" value="Caci_0903"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0903"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_6_11"/>
    <dbReference type="OMA" id="KWSPADQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="194"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="255"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="472" mass="49881" checksum="D3F9A245FF927657" modified="2009-10-13" version="1" precursor="true">MPLRSRLAVMSAVAVTIAIGAVSLISYIAVRDRLHEQMDKSIAAAGGPAGDQHFHDLYGVKVTATSPCDPPNDHPRPPPGGGNEYHAAAAVSITYYSSAETCALPGSTEVVGTPGDLQVAGQQQGTGLWRDGVTTAGDKVRIEAVPAPNPSGVLLKSQPYQPIDDSLSSLAWLLFVVSLLGIGGAATAGLLVARAALRPVDVLTSAVEHVARTEDLSVRMPVSGDDEIARLSESFNAMTAALQSSRDEQKRLVDDAGHELRTPLTSLRTSIDLLIRSEESGRALPEGKRTELLTGARTQMRELTVLIADLLELSRPEQASQVTAPVAFHEVTARAIERVRPRGAAREIPVAITEDLRPWTTHGDGAALERAVVNLLDNAVKFAPPGSDVQVRLLNGSLTVRDRGPGIPPEELPHVFERFWRSPTARALPGSGLGLAIAARAARESGGTIAFERPHDGPGTIARLSLPGTAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P0</accession>
    <name>C7Q2P0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ordered locus">Caci_0950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785177.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0950"/>
    <dbReference type="EnsemblBacteria" id="ACU69882">
        <property type="protein sequence ID" value="ACU69882"/>
        <property type="gene ID" value="Caci_0950"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0950"/>
    <dbReference type="eggNOG" id="COG0200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_4_1_11"/>
    <dbReference type="OMA" id="FKNINRV"/>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU69882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="146" mass="15348" checksum="E714469456B2292C" modified="2009-10-13" version="1">MTLKVHHLRPAPGAKTAKTRVGRGEGSKGKTAGRGTKGTKARYQVSARFEGGQMPLHMRLPKARGFKNPFKVTFQVVNLDKLSALFPAGGEVTVEDLIAKGAVRDNELVKVLGTGEVSVALQVKAHAFSASAKEKLAAAGGSAEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q353</accession>
    <name>C7Q353_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_4929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4929"/>
    <dbReference type="EnsemblBacteria" id="ACU73789">
        <property type="protein sequence ID" value="ACU73789"/>
        <property type="gene ID" value="Caci_4929"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4929"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_2_11"/>
    <dbReference type="OMA" id="SVAPFCK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="251" mass="27086" checksum="DA3CA7C24183C888" modified="2009-10-13" version="1">MVSVTSQDEDGARGGGSYRPGYELAAERILELIAESGLRPGDRMPTEIELAARLGTSRTVVREAVKILSALGRVSAQKGRGLYVADDEGMLGSAGWGGFFLPTDLDHVYMLFEFRRIQESAAARLAATHATPAELQVIETAAELCRQGHLTARSELFDRGDDDFHLGIAAASHNAFLLAAVREARRLQRQSSIIGLHGSVGGHAAEAVAEHAAIYRAIRDGDPDAAALAAAVHIENTLEDYRREIQRRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3B3</accession>
    <name>C7Q3B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793578.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4989"/>
    <dbReference type="EnsemblBacteria" id="ACU73849">
        <property type="protein sequence ID" value="ACU73849"/>
        <property type="gene ID" value="Caci_4989"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4989"/>
    <dbReference type="eggNOG" id="COG3533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013148_1_0_11"/>
    <dbReference type="OMA" id="LYSGMAD"/>
    <dbReference type="OrthoDB" id="194265at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Glyco_hydro_127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Glyco_hydro_127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="647" mass="70029" checksum="1C71783A4DA98584" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3S9</accession>
    <name>C7Q3S9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797411.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8874"/>
    <dbReference type="EnsemblBacteria" id="ACU77687">
        <property type="protein sequence ID" value="ACU77687"/>
        <property type="gene ID" value="Caci_8874"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8874"/>
    <dbReference type="eggNOG" id="COG0789">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079903_0_1_11"/>
    <dbReference type="OMA" id="ERGWTGW"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="28627" checksum="6B4962D62556BE83" modified="2009-10-13" version="1">MLTISQLADYVGVTVRAVRHYHQRGLLPEPDRDHSGYRRYDAQAVIDLIRIKTLAEAGVPLARIEELLAADAEQFTDAVAEIDRSMQDQIRELKERRRRVAQLASGERLFLPTEIAEYIEELRAVGVSDRGVLMERDGWVILAAAYPELAPRWIAHKRADLADPEYRDFYVTYDQAHDWQVDDPRLEALADTMAERFGKQLAEAGDQADELRMEKVLSAEEQKLFAEYVNDYSPAWVRLNEMVAKRIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3V2</accession>
    <name>C7Q3V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_8897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797434.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8897"/>
    <dbReference type="EnsemblBacteria" id="ACU77710">
        <property type="protein sequence ID" value="ACU77710"/>
        <property type="gene ID" value="Caci_8897"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8897"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="WRELHAM"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="24"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU77710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="222" mass="23771" checksum="E3C7BFCCD6007E8F" modified="2009-10-13" version="1">MTTPTPPRTAPRTGPLSGRKAQANRNDEAILRAAREVFVADPSAPISAVAKAAGVGISALYRRYESKEVLLQTLCADGLATYIECAEAALASDAPPWETFTDFVRAVIDADVHALTVNLAGTFTPTEEMFGQSVRAVELADAILKQAHEAGAVRPDFALTDIAMLLEQLTAVTGPGPERTRELRHRYLALHFDALRAHTAHSGLPGPPPSEEELGARWIPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q478</accession>
    <name>C7Q478_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785232.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69938">
        <property type="protein sequence ID" value="ACU69938"/>
        <property type="gene ID" value="Caci_1010"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1010"/>
    <dbReference type="HOGENOM" id="CLU_2315146_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="99" mass="10588" checksum="6E48AD784A0D4D0B" modified="2009-10-13" version="1">MSGLPEGDGWVEEGDGNDRWDGWVRALDAGRPPESGGGGGRGRGARGGKGDGERREEADEQAAGSPEDRPWTPIPRQAKSVERGLIPPQRRLKKTSRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q486</accession>
    <name>C7Q486_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_1018</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785240.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1018"/>
    <dbReference type="EnsemblBacteria" id="ACU69946">
        <property type="protein sequence ID" value="ACU69946"/>
        <property type="gene ID" value="Caci_1018"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1018"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_11"/>
    <dbReference type="OMA" id="KARLHAH"/>
    <dbReference type="OrthoDB" id="293754at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="59"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="550" mass="59094" checksum="52D806377FC0D64D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4C7</accession>
    <name>C7Q4C7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Roadblock/LC7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785281.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1061"/>
    <dbReference type="EnsemblBacteria" id="ACU69987">
        <property type="protein sequence ID" value="ACU69987"/>
        <property type="gene ID" value="Caci_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1061"/>
    <dbReference type="eggNOG" id="COG2018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094585_1_1_11"/>
    <dbReference type="OMA" id="SDLDWLM"/>
    <dbReference type="OrthoDB" id="1723871at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="11"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="142" mass="14489" checksum="E296268668455B3F" modified="2009-10-13" version="1">MSATNPPQDLDWLLGRIVERLPDARAAVLASADGVRTHRYGVDEDDGDRLAAIAVGLYSLGRGIGRFGGHSTDVVRQVIVEHADALLFVAGAAPGTVVAVLTTPDADSGLVGHEMAQAVAAVAKHLTTARRGSSGGLDGSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S4</accession>
    <name>C7Q4S4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5012</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793601.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5012"/>
    <dbReference type="EnsemblBacteria" id="ACU73872">
        <property type="protein sequence ID" value="ACU73872"/>
        <property type="gene ID" value="Caci_5012"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5012"/>
    <dbReference type="eggNOG" id="COG2186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_9_4_11"/>
    <dbReference type="OMA" id="DDPVPSH"/>
    <dbReference type="OrthoDB" id="1045165at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU73872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="239" mass="25415" checksum="34158E874EC0EAC2" modified="2009-10-13" version="1">MSVQVRGLHGQAVDVIGERIVRGDNAPGDLLYPDQIEAELGVSKTVVREALRVLASKGLIDSRQKRGTFVRPRADWNLLDADVLRWRGQGVPDEGFLDDLAEVRAIVEPAGARLAARRRTEADLVALTEAIEQMDAAGGDVPATVEADLAFHRALLAAAHNELLTGMEVVIEAGLRVRDSFVHGADHGPDDAVPAHRAVVDAIRAQDPDAASRAVEDLLAKAIADLRALIAGPDGTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4U6</accession>
    <name>C7Q4U6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent transcriptional regulator, MalT-like, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793623.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5034"/>
    <dbReference type="EnsemblBacteria" id="ACU73894">
        <property type="protein sequence ID" value="ACU73894"/>
        <property type="gene ID" value="Caci_5034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5034"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006325_2_0_11"/>
    <dbReference type="OMA" id="NAELCNA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="862"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="935" mass="99736" checksum="BA2CB15ACB23F81C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4X2</accession>
    <name>C7Q4X2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein-3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793649.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5060"/>
    <dbReference type="EnsemblBacteria" id="ACU73920">
        <property type="protein sequence ID" value="ACU73920"/>
        <property type="gene ID" value="Caci_5060"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5060"/>
    <dbReference type="eggNOG" id="COG0657">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_0_11"/>
    <dbReference type="OMA" id="INYALAP"/>
    <dbReference type="OrthoDB" id="1361074at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="3">
        <location>
            <begin position="82"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="34502" checksum="9FE452BF1F7E3374" modified="2009-10-13" version="1">MLDPVLEPAAQRLVEETDPHPHVYEVPLEQARARLRQLQAGDGVPKPEIDEEWVEVDAGAWGMVRARIVRPQGAAGMLPVFLYLHGGGWVVGDSDTHDRLVRELVVGSGAAAVFPLYDRAPEAKYPTQIEQSYAVVRWAVREGARHGLDAARLAVCGDSSGGGMAAALALMAKERGDVHIKAQMLLYPTLDANFETSSYQQFADHYYNTRAAMQWFWDQYTADPAQRTEPHASPLRATLEDLRGMPPTLLITGEADVLRDEGEAYAAKLREAEADVTALRILGTVHDFLLLDSLRDTNAAKLGRLLVIEALKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5M7</accession>
    <name>C7Q5M7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 17">Aspartokinase</fullName>
            <ecNumber evidence="7 17">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">Caci_9025</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7 17"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797562.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_9025"/>
    <dbReference type="EnsemblBacteria" id="ACU77838">
        <property type="protein sequence ID" value="ACU77838"/>
        <property type="gene ID" value="Caci_9025"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_9025"/>
    <dbReference type="eggNOG" id="COG0527">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009116_3_2_11"/>
    <dbReference type="OMA" id="DMIVQTI"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04261">
        <property type="entry name" value="AAK_AKii-LysC-BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041740">
        <property type="entry name" value="AKii-LysC-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="12 17 20" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 17 20" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="19">
        <location>
            <begin position="267"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00016273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ACU77838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="422" mass="44568" checksum="2FE01453064450A8" modified="2009-10-13" version="1" precursor="true">MGLIVQKYGGSSVADAESIKRVAKRIMETRRAGHEVCVVVSAMGDTTDELIDLAKQVSPIPEGREYDMLLTAGERISMSLVAMAINSMGGDARSYTGSQAGVITDQSFNRARITSVTPGRLRTALDEGAITIVAGFQGVSETTKDITTLGRGGSDTTAVALAAALGADVCEIYTDVDGVFSADPRLVPKARKLNRVTYEEMLELAASGAKILHLRSVEYARRFNVPIHVRSSFAQHEGTWVRAREEGETVEQAIIAGVAHDTSEAKVTVVGVPDKPGVAAQIFRTIADAELNIDMVVQNISAAATGRTDISFTLPVADGRRAITALQKVQPAIGFESLLFDDQIAKVSLVGAGMKSHPGVTAVFFEALSNVGVNAEMISTSEIRISVVCRADVVKDAVAALHTAFGLDADGEEAVVYGGTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q682</accession>
    <name>C7Q682_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787381.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3180"/>
    <dbReference type="EnsemblBacteria" id="ACU72088">
        <property type="protein sequence ID" value="ACU72088"/>
        <property type="gene ID" value="Caci_3180"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3180"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_3_0_11"/>
    <dbReference type="OMA" id="RLHHRKD"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="2">
        <location>
            <begin position="21"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="241" mass="26119" checksum="F596F0CCAAD5672D" modified="2009-10-13" version="1">MTGTQDSPRFRLAYVPGVTPAKWVHTWGERLPGVPLDLVSVTAAEAAATLIDGEADAGLVRLPVDRDKLSAIPLYAETTVVVVPKDHELTAVEEVALEELDPYIVQHPLDDCLEWDKLPGLPAISRPETTADAIELVAAGVGLLLVPQSLARLHHRKDLVFRPVNDVPQSQVVLSWLEGQTTDLVEEFIGIVRGRTVNSTRGRGAPEPAAKTKAAAKPKTPSRAPARSARSQKPAKPRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6B9</accession>
    <name>C7Q6B9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3218"/>
    <dbReference type="EnsemblBacteria" id="ACU72125">
        <property type="protein sequence ID" value="ACU72125"/>
        <property type="gene ID" value="Caci_3218"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3218"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038449_4_1_11"/>
    <dbReference type="OMA" id="NDAGFEQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="PTHR37981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982937" evidence="1">
        <location>
            <begin position="33"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="41"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="295" mass="29782" checksum="08E712AD6BF74722" modified="2009-10-13" version="1" precursor="true">MRSSRTVKAAVGLCALLGAVSVATATSAAAQAAATPQVYVALGDSMASGPLIPDPTGQLACARSTHNYAHDMAASLGIPVLRDVTCSGASTFHMTNPQPLSIAGVSAGTAPPQFDALTPDTTLVTLTIGGNDVGLVGVAQACEQLNPFAAPCEGKYVVNGVDSVAARSDAFAPKLAAVLAGIHQRSPQARVLVTGYGLYIKAGGCWPTQPLLGSDATWLQSEVDYLNGVIATTAAANGATYVDVRTPSAGHDSCQSESARWVEGFVPLSLAAPLHPNQAGEAAYARIVGAVVANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6F3</accession>
    <name>C7Q6F3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787452.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3252"/>
    <dbReference type="EnsemblBacteria" id="ACU72159">
        <property type="protein sequence ID" value="ACU72159"/>
        <property type="gene ID" value="Caci_3252"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3252"/>
    <dbReference type="eggNOG" id="ENOG502ZJ4A">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_189858_0_0_11"/>
    <dbReference type="OMA" id="ELAWLIH"/>
    <dbReference type="OrthoDB" id="1944620at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="66" mass="7233" checksum="BA652CACBB0E1A47" modified="2009-10-13" version="1">MLATYGERTPDEVPETVDSLELAWLIHQVEQHYGRPFDADDDALARMTTVTAVVRVLAELGFGGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6X5</accession>
    <name>C7Q6X5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase dimerisation and phosphoacceptor region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795716.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7159"/>
    <dbReference type="EnsemblBacteria" id="ACU75988">
        <property type="protein sequence ID" value="ACU75988"/>
        <property type="gene ID" value="Caci_7159"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7159"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_1_11"/>
    <dbReference type="OMA" id="VGHHISL"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="196"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="43145" checksum="5D9EDD6FC8E942EF" modified="2009-10-13" version="1">MSITGHLRGAVQRHPHPLDAAIALVLFVATAVTAFGGHQAFEAGDRGERGVLLAIVAIGCGALIARRRFPKIALLVSAGAAEMFFAKIGGSGSGSGGVLIVLAPSIALYTVAEQVERRSGLIACGAAVATFATVHALSHPAMLGAENLALTAIGALAIAAGDSSRTRRAYLAEVEARAERAEQAREQDASRRVAEERLRIARDLHDSVGHQLALISVQSDVAGRAIDTDGPAVREALAHVKAASRQALGELRDTVSLLRQPGDPVAPTEAPAPRLDALEDLLAALRTSGLEIDQAVRGSVTRLAPAADLTAYRVIQESLTNVSKHSSARRARLLLDYGPGELHVEIDDLSVGDAAVSPVLRSSLPRHGIVGMRERVLALGGQFTAGPGREPAFRVAATLPYQPLDLAVGSESES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7U2</accession>
    <name>C7Q7U2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787578.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3379"/>
    <dbReference type="EnsemblBacteria" id="ACU72285">
        <property type="protein sequence ID" value="ACU72285"/>
        <property type="gene ID" value="Caci_3379"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3379"/>
    <dbReference type="eggNOG" id="COG3293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055261_15_6_11"/>
    <dbReference type="OMA" id="PDRYGPY"/>
    <dbReference type="OrthoDB" id="2020052at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="105" mass="12138" checksum="BF29D116CFDBF1FD" modified="2009-10-13" version="1">MYGDLTDAEWDLLEPLLPIPPARGKGGRPRYRSRRELIDGIRWRFRESGRWDRIPDRYGPYQTTYALFYAWRKDGTWEQLVSALGAGPEARTIIPWVSAGGGVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q820</accession>
    <name>C7Q820_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5328"/>
    <dbReference type="EnsemblBacteria" id="ACU74187">
        <property type="protein sequence ID" value="ACU74187"/>
        <property type="gene ID" value="Caci_5328"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5328"/>
    <dbReference type="eggNOG" id="ENOG5033NVP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145444_0_0_11"/>
    <dbReference type="OMA" id="ANGWANY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="137" mass="14543" checksum="C93EA00D3B142E91" modified="2009-10-13" version="1">MPTWAKVALAGYAAGFLEGAGSHVAQIAGGGVHTYDGVRWPSQVLYYSLVLWDSLAVCLALRARPAVVPLGVAIMTLDLASNWYYNGSAIRADPGLFWAPVGLLPMSLFGLFVAVTAVPLWRVVRRRASVGSTPDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8K1</accession>
    <name>C7Q8K1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785560.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1343"/>
    <dbReference type="EnsemblBacteria" id="ACU70266">
        <property type="protein sequence ID" value="ACU70266"/>
        <property type="gene ID" value="Caci_1343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1343"/>
    <dbReference type="eggNOG" id="COG1694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110454_1_0_11"/>
    <dbReference type="OMA" id="KMDTNRQ"/>
    <dbReference type="OrthoDB" id="1760741at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11537">
        <property type="entry name" value="NTP-PPase_RS21-C6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025984">
        <property type="entry name" value="DCTPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12643">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029826">
        <property type="entry name" value="UCP029826_pph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="12546" checksum="7ACFB9A785149B15" modified="2009-10-13" version="1">MSDLDIATLQRRLIDFAEAREWGPYHTPKNLAMALSVEASELAEIFQWLTPEESADVMSDPDKAFRVRDEVADVMAYLLQLAGACGVDVLQALAEKIERNEMRFPPGPAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8L7</accession>
    <name>C7Q8L7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Na+/solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_1359</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785576.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1359"/>
    <dbReference type="EnsemblBacteria" id="ACU70282">
        <property type="protein sequence ID" value="ACU70282"/>
        <property type="gene ID" value="Caci_1359"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1359"/>
    <dbReference type="eggNOG" id="COG0591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018808_15_0_11"/>
    <dbReference type="OMA" id="PYVMLQQ"/>
    <dbReference type="OrthoDB" id="231452at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="572" mass="60814" checksum="949D6611E5DD2F26" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8P7</accession>
    <name>C7Q8P7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1389</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1389"/>
    <dbReference type="EnsemblBacteria" id="ACU70312">
        <property type="protein sequence ID" value="ACU70312"/>
        <property type="gene ID" value="Caci_1389"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1389"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_15_4_11"/>
    <dbReference type="OMA" id="TGMEANP"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014325">
        <property type="entry name" value="RNA_pol_sigma-E_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02983">
        <property type="entry name" value="SigE-fam_strep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="168" mass="19257" checksum="225EF2C11BBA09E0" modified="2009-10-13" version="1">MKEAQEESFREFVEGSWSRLLRTAYLLTADHGAAEDLVQVALMRTYRHWDRIEAYESPEGYVRRAMVNANISAWRRRKHVVHVMAEPPERPAESGDHQDAYAVRDELWRAVCAMSPRMRTVFVLRYFEDLTEAETAAVMGCAVGTVKSQIARGLTKLRGELRAEGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8W5</accession>
    <name>C7Q8W5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-carboxymethyl-2-hydroxymuconateDelta-isomerase</fullName>
            <ecNumber evidence="2">5.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.3.10" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785674.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1457"/>
    <dbReference type="EnsemblBacteria" id="ACU70380">
        <property type="protein sequence ID" value="ACU70380"/>
        <property type="gene ID" value="Caci_1457"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1457"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_3_4_11"/>
    <dbReference type="OMA" id="PPEPIIF"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008704">
        <property type="term" value="F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="77"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="286" mass="30748" checksum="969B42431EE5BE4C" modified="2009-10-13" version="1">MRLLRLGEPGRERPVLLAADGRHFDLTGVIGDLDRAFWVNQGAESVRAAAEAGTLPEIPAEDVAAARVGAAVARPGKVVCIGLNYRDHAEETGAAIPPRPVVFMKDPYTVVGPNDDILIPRASVKTDWEVELAVVIGARARYLESHEAALDVIGGFAVSNDVSEREFQLERSGQWDLGKSCESFNPLGPWLVTADEVGDFQKLGLRLAVNGEQRQNGNTENMIFGVAEVVHYLSQHMVLEPGDVINTGTPAGVALGMPDHPYLRAGDVVELEIDGLGSQRSNLVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q946</accession>
    <name>C7Q946_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787659.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72366">
        <property type="protein sequence ID" value="ACU72366"/>
        <property type="gene ID" value="Caci_3460"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3460"/>
    <dbReference type="eggNOG" id="ENOG502ZTTU">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1902905_0_0_11"/>
    <dbReference type="OMA" id="LIWRAVA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="13709" checksum="66735B890EE03325" modified="2009-10-13" version="1" precursor="true">MTTDSRLRTATAAGAALIALATALQFWPMPFLVALVLGILAVRRRARIAVLCATTAAAVGWSLPLIWRAVAGDPVLGTARVTAGLAGLPATGWLAILVTILVAVLQALAAVWVTRTFSALRATRTSPSPSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q960</accession>
    <name>C7Q960_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3474"/>
    <dbReference type="EnsemblBacteria" id="ACU72380">
        <property type="protein sequence ID" value="ACU72380"/>
        <property type="gene ID" value="Caci_3474"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3474"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056710_0_0_11"/>
    <dbReference type="OMA" id="FHYLEHS"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="371" mass="41395" checksum="0B43738F392C8ECA" modified="2009-10-13" version="1">MRVGATEEPETTRAGAIAARRPAYEADLEDGVERFFEPRRAVCAWCGSGRLRERLHTTDLLQHKPGAFRLDRCLDCGHIFQNPRLNADGLEFYYRDFYDGLGEKSTAGLFAGRGATYRRRAEALLPYTGLNTNTDIDTHALDSWLDVGTGHGHFCEAAREVFPQTAFDGLDFTDGAELAEKAGRVRRGYRGSFVEVAAAVAGTYDVVSMFHYLEHSVEPAMELEAARLALRPGGYLLIEVPDAASRYSRLLGRRWLPWLQPQHLHFLPVRNLRDRLAALGFTVVAEQHAEAHDRVDLLAATWLVLDGIAPRDEVPWLARRPGRGKRAARAMVVMLGIPVLLAATILDRIIPSALIRRLGLSNAYRVVARRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q967</accession>
    <name>C7Q967_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_3481</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787680.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3481"/>
    <dbReference type="EnsemblBacteria" id="ACU72387">
        <property type="protein sequence ID" value="ACU72387"/>
        <property type="gene ID" value="Caci_3481"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3481"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0753">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_3_0_11"/>
    <dbReference type="OMA" id="PRGDNEI"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="35"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="517"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU72387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="720" mass="78572" checksum="CC644E23CA960936" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9D4</accession>
    <name>C7Q9D4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5421"/>
    <dbReference type="EnsemblBacteria" id="ACU74280">
        <property type="protein sequence ID" value="ACU74280"/>
        <property type="gene ID" value="Caci_5421"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5421"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_59_0_11"/>
    <dbReference type="OMA" id="PLWIARG"/>
    <dbReference type="OrthoDB" id="1594866at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="433" mass="44295" checksum="0ECE4A784354201A" modified="2009-10-13" version="1" precursor="true">MLRHLTGTAGAVPGAAVSGSAESGGSRHGALAQYRWRLVAGLAVSQTVGYGVLFYVFSVFLIPTAHDLHTSTPVVTGALTASLLAAAAAAVPVGRHLDRHGGRLLMTGGSIAASVLVAVWSQVTSVWQLYAVWIGIGVASAAVLYEAAFAVLVPWFGADSRAKALLAVTIVAGFASSVFLPSAGYLLADLGWRDAVLVLAVAHAALTVPFHLYIRRPSQSSTKTAPDGRRRQIVSVALHDPVFWTLGCSLLAQGAAVFVMGVLLVAALRDFGHSATFAATTAGMLGVLSVSGRLAFTAAGRRASATDVAAAVFVVQGIGVGLLPLIGRTSLGAIACVLVFGLGFGVSTLIRPAVLTARYGTEAFATLSGLLTLPLTLVKALAPLVSAAWASAAHSYAPPLTASAGCCLIGAAAMAVIRQLERRRRPAFEPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9E0</accession>
    <name>C7Q9E0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794015.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5427"/>
    <dbReference type="EnsemblBacteria" id="ACU74286">
        <property type="protein sequence ID" value="ACU74286"/>
        <property type="gene ID" value="Caci_5427"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5427"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_20_7_11"/>
    <dbReference type="OMA" id="VENGSCH"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="228"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="437" mass="45666" checksum="62D034CD14A0E88F" modified="2009-10-13" version="1">MSASWITLGTATWRIAANRRAETDAPDVPPAPPSGHTGLIMSGTVDDFPDLRRWTERWPAAAVALRLLAIGALTFGIAQTHRPAAWALGGAAALSGVVWAVSPVHRMRILIPATAVFAVCGAILAGSGLAEPSGLTYIFMGLLFLQAVAEPRVTALYVGIAVLVAGAVSAVLAHHGGQYPWILAVVIGGYVSGDARRSRQLALHRAQDLLVMTRRANTEQAHAAALAERGRIARDVHDVLAHSLSGLAIQLEAADALLTDGADVERAHTMVIRARRLARDGLSEVRRAVTALREDVKPPEETLAVLAADYTQDTGWPATFEVLDGPVPELAVETAQTLQRVAQEALTNARKHAPGAAVQVRLAMEAETVTLTIENAAPTTPTAPLANSGGGWGLIGLRERVGLVGGSVETGATAGGGFRVAAVVPVVPWVAEGEFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9F8</accession>
    <name>C7Q9F8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPW repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794033.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5445"/>
    <dbReference type="EnsemblBacteria" id="ACU74304">
        <property type="protein sequence ID" value="ACU74304"/>
        <property type="gene ID" value="Caci_5445"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5445"/>
    <dbReference type="eggNOG" id="ENOG5032UXB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124842_1_0_11"/>
    <dbReference type="OMA" id="HASDITT"/>
    <dbReference type="OrthoDB" id="1941441at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005530">
        <property type="entry name" value="SPW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03779">
        <property type="entry name" value="SPW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="148" mass="16038" checksum="024FAA3C1CF44F3C" modified="2009-10-13" version="1">MSETAPRHASDITTHPDAREMQERFAKVVQGPRATALDGMVVLLGMYLAISPWVVHSIDANLRVNNLVIGLTLAAFGFGLALQPERLYRLGWICVPVGVWMIISPWVVTVGHTAGRAVIWNNVAIGAVAVLLGLASQGMTMGAVRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9L8</accession>
    <name>C7Q9L8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7360"/>
    <dbReference type="EnsemblBacteria" id="ACU76187">
        <property type="protein sequence ID" value="ACU76187"/>
        <property type="gene ID" value="Caci_7360"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7360"/>
    <dbReference type="eggNOG" id="ENOG502ZYA6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1329949_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="206" mass="21522" checksum="96AD65D4E760495D" modified="2009-10-13" version="1">MGDSGGGFYLDGKQHGPLVPGVAAEVFRRDGSFTVGVWGRDVTLGSDVVGVRQQRQLMVDGGRIAGDIDSLFTWGVTDGGATYVRRSGVGVTADGDVVFALGPTMSPRSLATALQRAGAVRAMELDINISWPSFMAYDSSGNPGDPRPFKWGDYPRSAERYFSHSARDFVAVYARATGAQGGACVDPAGVTRSRPGGDTLGGPLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL2</accession>
    <name>C7QAL2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3607"/>
    <dbReference type="EnsemblBacteria" id="ACU72511">
        <property type="protein sequence ID" value="ACU72511"/>
        <property type="gene ID" value="Caci_3607"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3607"/>
    <dbReference type="HOGENOM" id="CLU_419616_0_0_11"/>
    <dbReference type="OMA" id="WIEDHAD"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="653" mass="71381" checksum="2526E242810A1835" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAV4</accession>
    <name>C7QAV4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794156.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5568"/>
    <dbReference type="ESTHER" id="catad-c7qav4">
        <property type="family name" value="Aclacinomycin-methylesterase_RdmC"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74427">
        <property type="protein sequence ID" value="ACU74427"/>
        <property type="gene ID" value="Caci_5568"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5568"/>
    <dbReference type="eggNOG" id="COG2267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_0_0_11"/>
    <dbReference type="OMA" id="SWPDALC"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="30136" checksum="578381479E3609AA" modified="2009-10-13" version="1">MQIKVNGVEVCVETFGDEADPPVLLVGGVTMLSWPDGLCAALAERQRYVVRYDLRDAGRSTFADPDQPGYGLRDLVTDASELVTALDLGRAHVAGIGVGGFVAQLLALDHPEQVASLTLVSTRPVAPGPVDADLPDHSHEVLGQLFGRPAPDWTDRDSVVEYMTGSARLLAGSAGFDEKDARATAGAIFDRAGDTAQAQVASHLGTVFAALDCKPRWRERLGEITAPTLVVHGDEDAFFPHGNGVALAAEIPGASLLTLPGVGVGQGLPRAAWPAVVEAFDALVDQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB01</accession>
    <name>C7QB01_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bc1 complex Rieske iron-sulfur subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cytochrome bc1 reductase complex subunit QcrA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">Caci_5615</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794203.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5615"/>
    <dbReference type="EnsemblBacteria" id="ACU74474">
        <property type="protein sequence ID" value="ACU74474"/>
        <property type="gene ID" value="Caci_5615"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5615"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_1_0_11"/>
    <dbReference type="OMA" id="RRDFINW"/>
    <dbReference type="OrthoDB" id="1632945at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983083" description="Cytochrome bc1 complex Rieske iron-sulfur subunit" evidence="12">
        <location>
            <begin position="39"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="13">
        <location>
            <begin position="83"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACU74474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="159" mass="15306" checksum="4D92DC49CDC36F25" modified="2009-10-13" version="1">MSDHVEVEESGPGRRSVMKAAALVAVPVAGVGTVAACASSSSSKSSSSGSGGGSGSGSGNGSVSVPVSSVPVGGGYIDKSNLVVVTQPEAGQYKAFTAVCTHQGCTVASVTNNRIVCPCHSSVFSATDGSVINGPATSPLSAMTAAVNGENVDVTGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBC9</accession>
    <name>C7QBC9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_7596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796145.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7596"/>
    <dbReference type="EnsemblBacteria" id="ACU76420">
        <property type="protein sequence ID" value="ACU76420"/>
        <property type="gene ID" value="Caci_7596"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7596"/>
    <dbReference type="eggNOG" id="ENOG5032SSX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097507_0_0_11"/>
    <dbReference type="OMA" id="AAQGHWN"/>
    <dbReference type="OrthoDB" id="2003347at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="3">
        <location>
            <begin position="140"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU76420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="27616" checksum="CCD05AB64E33E0EE" modified="2009-10-13" version="1" precursor="true">MTDPGAPVTPPPGVPIDIGRDAARRAAADELAKPAYAHARPSLTRRALDWIGHELTTLWDKAFGSGSGGGSRGWTAVLAVLALLVVVAVVIRRRYGPVRRRVTDDQALFDEAATLDAAGYRRASEEHAAGGRWAEAVRDRLRAVIAALEERAVLDPRPGRTADVAAREAGALLPEQAPALRAAARVFDDIWYGQAAARPEDYRRLVAVDEAVAAARVRVPAGSAAGLVGGSLAGELPRLAETSETSSYSATPSGPADPPERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBG5</accession>
    <name>C7QBG5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785836.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1621"/>
    <dbReference type="EnsemblBacteria" id="ACU70542">
        <property type="protein sequence ID" value="ACU70542"/>
        <property type="gene ID" value="Caci_1621"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1621"/>
    <dbReference type="HOGENOM" id="CLU_1683407_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="15166" checksum="8FAD942DE4D0AF9D" modified="2009-10-13" version="1">MGIFDVFKTKVSGAADKAGDVAGQAWDKAGGVAGQAKDKVSDMMDKKKGEAADPSAPPAAHAPAGAEADSEAGASTMVSEGAPVATAGEAAPGVGDDGAPPKDSAGGMTQSIKGNAASGADQAGEMRAGEMAEGATGNRFDEKTDSGVRQAKDKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBP6</accession>
    <name>C7QBP6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785917.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1702"/>
    <dbReference type="EnsemblBacteria" id="ACU70623">
        <property type="protein sequence ID" value="ACU70623"/>
        <property type="gene ID" value="Caci_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1702"/>
    <dbReference type="HOGENOM" id="CLU_2697834_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="73" mass="7692" checksum="25F984FB202BA849" modified="2009-10-13" version="1">MGNQQLNARVPDVIAEAARAAAADAGVNLGEYLARLIDADTRGRRAVFDAVFDQFVQDAKASGAFDDDLQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBQ7</accession>
    <name>C7QBQ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger UBP-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785928.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1713"/>
    <dbReference type="EnsemblBacteria" id="ACU70634">
        <property type="protein sequence ID" value="ACU70634"/>
        <property type="gene ID" value="Caci_1713"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1713"/>
    <dbReference type="eggNOG" id="COG5207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163943_1_0_11"/>
    <dbReference type="OMA" id="WGWCYVD"/>
    <dbReference type="OrthoDB" id="1674309at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBP-type" evidence="1">
        <location>
            <begin position="29"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="100" mass="11216" checksum="78BA8655FA2F4F13" modified="2009-10-13" version="1">MPIPVYVPANGGRCAHLDQLRDAEPDSADECRECRATGSRWLHLRECLICGHVGCCDNSQNRHATAHWRATGHSVIRSLEPGEVWAWCYPDEAMLLRADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBV9</accession>
    <name>C7QBV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792307.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3676"/>
    <dbReference type="EnsemblBacteria" id="ACU72578">
        <property type="protein sequence ID" value="ACU72578"/>
        <property type="gene ID" value="Caci_3676"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3676"/>
    <dbReference type="eggNOG" id="COG0655">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050993_3_1_11"/>
    <dbReference type="OMA" id="DSINHFF"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="11"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="227" mass="25087" checksum="E5C99BD1E631C12A" modified="2009-10-13" version="1">MDFAHTERPLIFGIGGSERPAGNTDIALATAGELVRSRGARFDSIQLRDFDISPCSPCGDCNSRTLPCAIGDDTPAIVERMKRADGIIYATPVHGFGLAHLMQIFIEHVGVGHLRFERPLANKVGGVIITSRRYSDSNVYHQLVDNILLNRMILVGSGFPALMRNASAVPGMFDTESNDALERMVHRMVDMVELLRERTAERGEPVLPTVDVNERVVRRRGHPVRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCI2</accession>
    <name>C7QCI2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7621"/>
    <dbReference type="EnsemblBacteria" id="ACU76445">
        <property type="protein sequence ID" value="ACU76445"/>
        <property type="gene ID" value="Caci_7621"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7621"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_9_4_11"/>
    <dbReference type="OMA" id="YSHEVGM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="200" mass="22197" checksum="1960568A6EF43F0C" modified="2009-10-13" version="1">MPIRAIVLDIGGVLEHTPDLGTAARWEPEFGAGWANRVEAVFQAGELGHITLEEVHERSVAALGVPADRFAAYMADVWVEYLGTYNAEMADYWRARRAEGYATAIISNSFVGAREREEEAYRFSELTDLIVYSHEVGMQKPDPGIYELCLERLGIPAEETVFVDDLEANCAAARALGMSAILFQDTAQVIRELDELLLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD09</accession>
    <name>C7QD09_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1798"/>
    <dbReference type="EnsemblBacteria" id="ACU70719">
        <property type="protein sequence ID" value="ACU70719"/>
        <property type="gene ID" value="Caci_1798"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1798"/>
    <dbReference type="eggNOG" id="COG2071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030756_4_0_11"/>
    <dbReference type="OMA" id="PTYHHQA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="26609" checksum="1401C57A78BD2665" modified="2009-10-13" version="1">MPAPLIGLSMYQETASWGAWKNVPASLLPHAYVESVTRAGGVPLLLPQHLEHDADDLNKAEAEEVVGILHGLILTGGPDIDPSGYGAVRHLDTDSPRRGRDAWEFALLAAALARNIPVLAICRGFQLLNAALGGTLRQHLPDESVFGDAHRKQLGQFAAVRIDLDPAAPPGRVLGTQIIAWCHHHQGIDKLGAGLQSSGNAPDGLIEAAWMPEKDYVVGVQWHPEEDSKPELFRSLTDAATRYAKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD38</accession>
    <name>C7QD38_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786042.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1827"/>
    <dbReference type="EnsemblBacteria" id="ACU70748">
        <property type="protein sequence ID" value="ACU70748"/>
        <property type="gene ID" value="Caci_1827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1827"/>
    <dbReference type="eggNOG" id="COG1232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039679_0_0_11"/>
    <dbReference type="OMA" id="DFHPVTV"/>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="433" mass="45817" checksum="6CD0773570C6A2BA" modified="2009-10-13" version="1">MTAQSPSHRHHLDADVIVVGAGVAGLHAAGRLHEAGLDVLVVEASDRVGGRAGTERVSGFVVDKGFHLMNSGENGENAKLELGCFAPGVDLQLDGKRIRYGDRAGSDGALGAGNVLRTPLGSPAERRRQTGWLLRVALNRPESILDCPERTAAELVAEVGLSRRVIDGFLRPYLEAFAAEPDPDLSVSGRAMELALRQLVRGRWCLPASGIAAIPQRLAERLPTGAVRLETEVLMVYANGVVTADEVLRSSAVVVATDAATAVELLPGLHEPESRSVTAFHHATVLPPPRAEPAVLIDADPHSPVARTAAVSHAVPARSPDGRTLVSTNVVGHTGTRTSELEAAVRARLAELYPGGDDRWECVAVHHFPHAVPAMTSPHNFRRPVRLLHGLYVCGDHRGTAGIDGAMESGQRAARSVLADLGVSFRTGELVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD92</accession>
    <name>C7QD92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">Caci_3783</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792414.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3783"/>
    <dbReference type="EnsemblBacteria" id="ACU72685">
        <property type="protein sequence ID" value="ACU72685"/>
        <property type="gene ID" value="Caci_3783"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3783"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_6_11"/>
    <dbReference type="OMA" id="RSDANFW"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="707"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="744"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="818"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="848"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="928"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="958"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="44"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="352"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="709"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="1025"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1274"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="1064"/>
            <end position="1071"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU72685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1301" mass="138653" checksum="DABC16C072F2F638" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDG4</accession>
    <name>C7QDG4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792486.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72757">
        <property type="protein sequence ID" value="ACU72757"/>
        <property type="gene ID" value="Caci_3863"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3863"/>
    <dbReference type="eggNOG" id="COG5635">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1140959_0_0_11"/>
    <dbReference type="OrthoDB" id="865342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="26547" checksum="680BD6E9B5B759E6" modified="2009-10-13" version="1">MEHDGSLSFALPVFEQHFGAPAISSGTFEIEAAASRDSFPSWRYSIASAVATCPDSAEREQPLCRVACTNPAALSWILDEIEPEATCRNANAGSHEAPSNLDRNAGGPGTSSDTQADSAIAAGLWLREALQALLDGYGSLATPLAHHSEDRLVQWGTHLASGYMTLPEHWGQTIPAMVSLPDFTHLRDLRPGGWRASQMFTEPCGDYGRWHWDRNRILKTLTEVIQRQALPTSAGTRINHERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDM0</accession>
    <name>C7QDM0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5786</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5786"/>
    <dbReference type="EnsemblBacteria" id="ACU74644">
        <property type="protein sequence ID" value="ACU74644"/>
        <property type="gene ID" value="Caci_5786"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5786"/>
    <dbReference type="HOGENOM" id="CLU_307312_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="962" mass="104536" checksum="022AD225D2ACB964" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR0</accession>
    <name>C7QDR0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Penicillin-binding protein transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5826</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5826"/>
    <dbReference type="EnsemblBacteria" id="ACU74684">
        <property type="protein sequence ID" value="ACU74684"/>
        <property type="gene ID" value="Caci_5826"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5826"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025328_0_0_11"/>
    <dbReference type="OMA" id="QGGVRMN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983053" evidence="2">
        <location>
            <begin position="20"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="299"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="590" mass="58891" checksum="BE45C72CFE17F3B2" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDX3</accession>
    <name>C7QDX3_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_7737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7737"/>
    <dbReference type="EnsemblBacteria" id="ACU76561">
        <property type="protein sequence ID" value="ACU76561"/>
        <property type="gene ID" value="Caci_7737"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7737"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_1_1_11"/>
    <dbReference type="OMA" id="NAKAWLF"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014293">
        <property type="entry name" value="RNA_pol_sigma70_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02947">
        <property type="entry name" value="SigH_actino"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="79"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="185"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="28430" checksum="9797ACC11C455223" modified="2009-10-13" version="1">MTLALKHRRPAVKIDLSGVEPWISSSGKPEEVRTVAVTADDARGEAVIAEAVSTDAPRVDPGESEDARNERFERDALVYLDQLYPAALRMTRNPADAEDLIQETFAKAFASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQVSPTEEIEDWQLARAESHSSAGLPSAETVALDHLPDSDVKEALQAIGEEFRIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRAMLEDYARERGLVAAASEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF05</accession>
    <name>C7QF05_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5905"/>
    <dbReference type="EnsemblBacteria" id="ACU74763">
        <property type="protein sequence ID" value="ACU74763"/>
        <property type="gene ID" value="Caci_5905"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5905"/>
    <dbReference type="HOGENOM" id="CLU_1346877_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="203" mass="21408" checksum="68FDD83C8F1B326C" modified="2009-10-13" version="1">MMANPEMPGTQKEDAASATEATHPSPAAEPTTATPEVPRPRRESAEAKRSVVDAGESAAAQSPANTRQPAEPRRRPASAPAAAYEPEPERMPLLARVLLADFAVAVVALVVLFIIEVQRFDDATVHLRRQAWIEDLAVLFLVSVLFGVVTFLLFRAGRTRVALVQVVVTALVLIAAITSAATGDPKPTSADIPTPTGSSSNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF14</accession>
    <name>C7QF14_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794501.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5914"/>
    <dbReference type="EnsemblBacteria" id="ACU74772">
        <property type="protein sequence ID" value="ACU74772"/>
        <property type="gene ID" value="Caci_5914"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5914"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_5_11"/>
    <dbReference type="OMA" id="GRCAYEA"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="243" mass="25626" checksum="1DE97B1A690B8144" modified="2009-10-13" version="1">MPDRTTSGAAVFAGTAPGPDPERGPALNLPRVLGHHSLREQVSHALRAALIAGELRPGVVYSAPVLAAGFGVSATPVREAMLDLAKEGLVEVVRNKGFRVTELSEADLDQFTEIRALIEVPVVTGLARGAALGDLQALRPAAEAIVTAAKARDLIGYVEADQAFHLALLGLSGNPHLVEVVSDLRNRSRLYGLPSLADAGALASSAEEHVQLVDALVARDADRVEALMKTHLTHVRSIWAGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF89</accession>
    <name>C7QF89_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74847">
        <property type="protein sequence ID" value="ACU74847"/>
        <property type="gene ID" value="Caci_5989"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5989"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1944845_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="129" mass="14297" checksum="C0A33196C84812A0" modified="2009-10-13" version="1">MTPAVLRELFLNVTTAESVRIDVVLRCEDFGGVARVVPAAAGEWGPADYAWPLTYASDAVLVQHSLRRCLRTKDRMTLRSGYARLARLAGPEAVWAMELEYVGSLELMDPVVRSSMQAGDTDVLLKWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFC6</accession>
    <name>C7QFC6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S8 and S53 subtilisin kexin sedolisin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_7880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7880"/>
    <dbReference type="EnsemblBacteria" id="ACU76703">
        <property type="protein sequence ID" value="ACU76703"/>
        <property type="gene ID" value="Caci_7880"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7880"/>
    <dbReference type="eggNOG" id="COG1404">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_0_11"/>
    <dbReference type="OMA" id="APEMWAK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="31"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU76703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="34639" checksum="8004144CFA20DED8" modified="2009-10-13" version="1">MAGSLASASTSNQWALRYLRADSVWQISRGAGAEIAVIDTGVQANADVSNHLLPGADFSDSTTTSVGTGHLDTDSYGHGTGEASLIVGAGAETQGLAPDSNILPIRAVNGYAVDLALGITPAIEFAVSHKARVINLALGYKQDDPDIRRAVQDALDSDVVVVAAVGNDGSSQQYYPAALPGVVGVGAIDSSGEVWGQSNTGADVALVAPGVHILRDDNRGRVGYSDGTSEATAYVSAAAALVRSAHPGWSAGEVVAALEGTADKPAGMRGAVRDDRYGAGILDVLAAVRLAEPPVVGGSGAGVVRARQGGGSGWLWWVVGGGAVAGGVVMLFGVRRWFRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFF9</accession>
    <name>C7QFF9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, B subunit</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796461.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7913"/>
    <dbReference type="EnsemblBacteria" id="ACU76736">
        <property type="protein sequence ID" value="ACU76736"/>
        <property type="gene ID" value="Caci_7913"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7913"/>
    <dbReference type="eggNOG" id="COG2057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019942_4_1_11"/>
    <dbReference type="OMA" id="VAMMHTN"/>
    <dbReference type="OrthoDB" id="1380130at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:3-oxoacid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="221" mass="22744" checksum="7E1DB4149461D7EF" modified="2009-10-13" version="1">MPLTRDQLAARAARELRDGSYVNLGIGLPTLIPGHLPPGVEVVLQSENGILGLGPYPAPDAIDSDLVNAGKETVTVRAGSSFFDSATSFGMIRGGHIDTAVLGAMQVSASGDLANWTVPGKLVKGMGGAMDLVHGARRVLVVMEHTAKDGSPKLLQECTLPLTGKGVVDRVITDLAVLDVTPEGFRLVELAPGVSVEEVVANTAAPLDVAAAHISGPGTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFL6</accession>
    <name>C7QFL6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amidinotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796518.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7970"/>
    <dbReference type="EnsemblBacteria" id="ACU76793">
        <property type="protein sequence ID" value="ACU76793"/>
        <property type="gene ID" value="Caci_7970"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7970"/>
    <dbReference type="eggNOG" id="COG1834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057463_0_0_11"/>
    <dbReference type="OMA" id="LWAGYGP"/>
    <dbReference type="OrthoDB" id="592329at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="30456" checksum="DC23A0518AA4434C" modified="2009-10-13" version="1">MIPETPLVPSAAQRVAIPRRYLMCPPDHFAVTYSINPWMDPEEPVDASLAARQWEALRDAYLDLGHQVDSIKPIEGLPDMVFAANGATVVGGKVLGAAFRNDERKAEGPAYMEWFRKNGFPQIHDPQFINEGEGDFLYAGDWILAGHGFRSDPNAHLEAQEFFGMPVIGLRLVDPRYYHLDTALAVLDKDTVAYFPEAFSPGSQAVLRTLYPDAVIATAEDAAAFGLNAVSDGLHVLLPQAATGLAAQLAERGYEPIGMDLSELLKAGGSVKCCTLELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFZ3</accession>
    <name>C7QFZ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2050"/>
    <dbReference type="EnsemblBacteria" id="ACU70970">
        <property type="protein sequence ID" value="ACU70970"/>
        <property type="gene ID" value="Caci_2050"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2050"/>
    <dbReference type="eggNOG" id="ENOG502ZBYF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069617_0_0_11"/>
    <dbReference type="OMA" id="WRKPVTF"/>
    <dbReference type="OrthoDB" id="1464866at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="273" mass="29057" checksum="23FF791E5EF7C21E" modified="2009-10-13" version="1">MTAATSASAAPPHPAPPAWWVAVREIWTHGRRIERVCYVLGLVLITSGAFHFTVFFIRGGPWEGPVSWRKPTTFGLSFGLTLIAVAWVASSLKLSERTRALALGIFAADCFVEVGGITLQAWRHVPSHIDMQGSFNTGVSMTLAVGGGILVLVLGRLAFAAFRGDPDQAPSMRLALRAGFLTLMIGLLSGAAMIARGTSEANTGHQQQAYQDLGFLKLVHGISLHGVLVLPTLAWALTLTSWPEPKRTRTVALAASAYGIAIAAALVFDLATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG14</accession>
    <name>C7QG14_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2072"/>
    <dbReference type="EnsemblBacteria" id="ACU70991">
        <property type="protein sequence ID" value="ACU70991"/>
        <property type="gene ID" value="Caci_2072"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2072"/>
    <dbReference type="HOGENOM" id="CLU_3355231_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="36" mass="3979" checksum="F6866E572ADCDDE2" modified="2009-10-13" version="1">MPDSEFHYRTGIVKDIRPRAMINARPVIGSDPPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG73</accession>
    <name>C7QG73_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792647.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4053"/>
    <dbReference type="EnsemblBacteria" id="ACU72918">
        <property type="protein sequence ID" value="ACU72918"/>
        <property type="gene ID" value="Caci_4053"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4053"/>
    <dbReference type="HOGENOM" id="CLU_2341619_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="97" mass="10499" checksum="1A1B6F222D3844BE" modified="2009-10-13" version="1">MTAADDAVRESESEFLDAVIRLRAEHGEPNPLSDGQRAGNIAVARTLARRYGDASPGADALSYVIMYSIAEQTDGLTDAEGFAKRYLSLVKTYFPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGN5</accession>
    <name>C7QGN5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_6058</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6058"/>
    <dbReference type="EnsemblBacteria" id="ACU74915">
        <property type="protein sequence ID" value="ACU74915"/>
        <property type="gene ID" value="Caci_6058"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6058"/>
    <dbReference type="eggNOG" id="COG4585">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042141_0_0_11"/>
    <dbReference type="OMA" id="AWILVED"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045975">
        <property type="entry name" value="DUF5931"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19354">
        <property type="entry name" value="DUF5931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5931" evidence="5">
        <location>
            <begin position="102"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="4">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="407"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="501" mass="51856" checksum="469C26E61B2F73E5" modified="2009-10-13" version="1">MNGPGDPTSPVLPMPAAEAVEGAKKAERVEGVAVAEGVESVSVAEVAEAIEAVAAAPEAAEISEASEVPVLPVSQNPQPMLEPVPEPRPAPNSPPQPSPQQRPAVDSAMWRALGFFRSLALFYAVARFAASYDRYAHIGPAVVVLFTMAVWTAWTGIVYHRTTTTRRALLSFLAADFAVGAAAVLSTDLVDTRARIEAGALTLPTVWSAAPVIAVAIALGWRGGVAAAALMGGADLLERGALSQDLIHNAVLMVLTGAAVGYLTALGRTAELTLVRAQRLEAATRERQRLARDIHDGVLQVLALVQRRGAEIGGASRDLGRMAGEQELALRSLVNSWHEVEGADAGGDPVDLDLSALLGRLAGPRVTLAGPGAPVPLPSAVAREVAAAAAAALDNVRAHGGPGADGLGARAWILVEDEGDGVIVTVRDDGPGIPEGRLEEARRAGRLGVAHSIQGRLRDVGGTVDVVSVPGQGTEVEMRVPRPPAPSGAGHGDLKTIWRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH70</accession>
    <name>C7QH70_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796645.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8097"/>
    <dbReference type="EnsemblBacteria" id="ACU76920">
        <property type="protein sequence ID" value="ACU76920"/>
        <property type="gene ID" value="Caci_8097"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8097"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125944_0_0_11"/>
    <dbReference type="OMA" id="QRVEFGM"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU76920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="131" mass="14199" checksum="6CA7B404302EA65E" modified="2009-10-13" version="1">MPTGKIKWYDTEKGFGFITRDDGPDVFMHSSALPAGTAELKSGQRVEFGVAAGKRGDTAIGVKLLETRPSVEAAVAARDRKPAEEMVVIVEDVMKLLDGMSETFRRGKYPDKATSRKLAGVLRAVADQLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH77</accession>
    <name>C7QH77_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA dehydrogenase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0061"/>
    <dbReference type="EnsemblBacteria" id="ACU69016">
        <property type="protein sequence ID" value="ACU69016"/>
        <property type="gene ID" value="Caci_0061"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0061"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_5_3_11"/>
    <dbReference type="OMA" id="HRYHAWA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="2">
        <location>
            <begin position="217"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="359" mass="37976" checksum="3C20D1ADB30D1A3C" modified="2009-10-13" version="1">MDQPVDDALEAIGELSSEVFKDLDIETTRSPAYSNEAVSDEHDRRLWRILADTGLLAAVLPASVGGGGTGLPGMVRLLSDAGAALARLPLVETFVAVSVIDEKHLPAVLSGELVITAALAEHPSTITAPLRLTGQRLNGITQLVPYPLSSDLVLVPALREDDTEVLALVSLSTARVGDQVTTTGEPLGVLEFIDAEVMELCDAVGEARALAALFSSATLCGIAARALAMTAEYVGGRVQFGHPLATFQGVALSAADRYIDSRAMQAALWDAVYAIAENGISSPRARYAIATARVWAADGARRVVGSAQHLHGGFGVDVTYPLHRYHAWARYWELYGGSAEAWSGDLGELIAAHPIEEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHR1</accession>
    <name>C7QHR1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAGPA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2167"/>
    <dbReference type="EnsemblBacteria" id="ACU71086">
        <property type="protein sequence ID" value="ACU71086"/>
        <property type="gene ID" value="Caci_2167"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2167"/>
    <dbReference type="eggNOG" id="ENOG502ZYA6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430051_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="NAGPA" evidence="3">
        <location>
            <begin position="445"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="636" mass="70125" checksum="938F47A92771CCCC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QI44</accession>
    <name>C7QI44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carbohydrate-binding CenC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_4225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792818.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4225"/>
    <dbReference type="CAZy" id="CBM16">
        <property type="family name" value="Carbohydrate-Binding Module Family 16"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73089">
        <property type="protein sequence ID" value="ACU73089"/>
        <property type="gene ID" value="Caci_4225"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4225"/>
    <dbReference type="eggNOG" id="COG3469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019399_1_1_11"/>
    <dbReference type="OMA" id="FTAQTTC"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003305">
        <property type="entry name" value="CenC_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02018">
        <property type="entry name" value="CBM_4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983241" evidence="6">
        <location>
            <begin position="39"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="7">
        <location>
            <begin position="245"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU73089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="551" mass="56567" checksum="DCE17E1DEC0C1849" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIH6</accession>
    <name>C7QIH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794782.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6199"/>
    <dbReference type="EnsemblBacteria" id="ACU75053">
        <property type="protein sequence ID" value="ACU75053"/>
        <property type="gene ID" value="Caci_6199"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6199"/>
    <dbReference type="eggNOG" id="ENOG5032TCG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129241_0_0_11"/>
    <dbReference type="OMA" id="GYCPDVT"/>
    <dbReference type="OrthoDB" id="1358015at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="177" mass="18599" checksum="37DD5D96D020B84C" modified="2009-10-13" version="1">MPIRHYSYVGPADIKAMVAGSPAGTALTGLDALARWHAAQPPDERAEPFTYVVGLDGVLRVAPRRSEHVACAGGASVLAAGEIAFECGDGQWSVTSVSNQSTGYCPDVTCWPAVAAALDQLGVAHPAAFTTEVQFRRCLNCRELTIVRDGDFVCVFCDADLPAGWNIGAPISPDPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJD1</accession>
    <name>C7QJD1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786447.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2236"/>
    <dbReference type="EnsemblBacteria" id="ACU71154">
        <property type="protein sequence ID" value="ACU71154"/>
        <property type="gene ID" value="Caci_2236"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2236"/>
    <dbReference type="eggNOG" id="ENOG50334T2">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094847_2_0_11"/>
    <dbReference type="OMA" id="TVGLWHT"/>
    <dbReference type="OrthoDB" id="1986919at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025358">
        <property type="entry name" value="DUF4262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14081">
        <property type="entry name" value="DUF4262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="185" mass="20995" checksum="44E9A739B41BB2F5" modified="2009-10-13" version="1">MDIEPAPCRCLLCQPATPDESQWDPRDRAIATNVRDHGWHIMGVTGDDTPDWAYSIGMWHTHGGYDICMTGLPVENAMALVAKIAVQVREGRALGAEKRRLNVIEGYEVATRPVHQSWYPAMFGAGLDFFQTPPWPMLQAVWPDRQGRFPWEQGADPERQDQQPFLWLARNEHPDSVWVSSSLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK1</accession>
    <name>C7QJK1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2306</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786517.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2306"/>
    <dbReference type="EnsemblBacteria" id="ACU71224">
        <property type="protein sequence ID" value="ACU71224"/>
        <property type="gene ID" value="Caci_2306"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2306"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_3_11"/>
    <dbReference type="OMA" id="WMLMGYL"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="538"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="26"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="581" mass="61155" checksum="B8EA104D98C5C35C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJK2</accession>
    <name>C7QJK2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786518.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2307"/>
    <dbReference type="EnsemblBacteria" id="ACU71225">
        <property type="protein sequence ID" value="ACU71225"/>
        <property type="gene ID" value="Caci_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2307"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_15_1_11"/>
    <dbReference type="OMA" id="LARCGPM"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="16291" checksum="AF3EC31ABB49DB69" modified="2009-10-13" version="1">MNSSPTQPDTEVAARLRVALGRLNRQLLQRQSEASFAQLSALFVIEKWAPIRIGDLAQREKVAAPSMTRTLSGLVAAGWVQREPDPDDGRSFMVTLTPGGEALISKVRKQRTAALVQGMERLTPAQLEALHAAVPVLEQLASEVEPKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJZ9</accession>
    <name>C7QJZ9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792966.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4373"/>
    <dbReference type="EnsemblBacteria" id="ACU73237">
        <property type="protein sequence ID" value="ACU73237"/>
        <property type="gene ID" value="Caci_4373"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4373"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084253_1_1_11"/>
    <dbReference type="OMA" id="KTPDADW"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="PTHR43175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="19584" checksum="D15FF0086A8AC496" modified="2009-10-13" version="1">MSSRFATFLERNEAFAATDAKLRVPEIPFIPFRQVYLLTCIDPRVEPAAIAGVDLGEAIIARNIGGRVTDSAINDLAWVCHLHENKTPDADWFEVAILHHTDCGSGLFADPDLRRSFAERGGYDERTAAALAVLDPAATVRHDVELLRRAPVLAGSIAKLRIGGYDYDIKTGAITTVVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK48</accession>
    <name>C7QK48_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794851.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6268"/>
    <dbReference type="EnsemblBacteria" id="ACU75122">
        <property type="protein sequence ID" value="ACU75122"/>
        <property type="gene ID" value="Caci_6268"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6268"/>
    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043026_0_0_11"/>
    <dbReference type="OrthoDB" id="499077at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="6">
        <location>
            <begin position="35"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="305" mass="34585" checksum="68C077C1C6D104B7" modified="2009-10-13" version="1">MTSISSGTLLADDLDMLESESIHIVREVAGEFDRPVILFSGGKDSTVLLHLAVKAFWPAPVPFPLLHVDTGHNFEEVIAFRDRIAERYGLRLEVARVQEWIDDGRLAERPDGLRNPLQTLPLLDAINSLRYDAAFGGARRDEERARAKERIFSLRNGFGQWEPRRQRPELWNLYNGRHRAGEHVRVFPLSNWTERDIWRYVEREGIELPSIYFAHRRAVFRRSGMWLTAGPWGGARPGEDVHELTVRYRTVGDGSCTGAVESEASSVAEVIAEVAASRLTERGASRADDLVSEAAMEDRKRTGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK92</accession>
    <name>C7QK92_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794895.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6312"/>
    <dbReference type="EnsemblBacteria" id="ACU75166">
        <property type="protein sequence ID" value="ACU75166"/>
        <property type="gene ID" value="Caci_6312"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6312"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_806350_0_0_11"/>
    <dbReference type="OMA" id="HCFGSDN"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="1">
        <location>
            <begin position="122"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="315" mass="33220" checksum="B17374094EED37B0" modified="2009-10-13" version="1">MNLNQTTGVFVRAPRYVLGEITRKHDEIDGFAEFVDEARMVPDADLWGWGEVHQTALTTAELAVEAGSRTLAAAAVEPGEVDALVLCSTRFPAEIAQHGELIATVLRGLELGPVPVTGVTLNRCANLLVGLRVAAAMVAAGQHRTVLVITTDRVAEESERLTEFALFSDGAASCLVTQQADTAGDSYEWVADAGALDPAALGRVTEISADLAKVANAQLCAEAGITLDAIDGLLHNNIYLPIVTMKEVQAGFSLSQLDTANIARVGHCFAADPLINLADRRSAGTIRPDGLYLLASSVSGFRVCVLLRAGESLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB5</accession>
    <name>C7PVB5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, HxlR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0318"/>
    <dbReference type="EnsemblBacteria" id="ACU69271">
        <property type="protein sequence ID" value="ACU69271"/>
        <property type="gene ID" value="Caci_0318"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0318"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_0_0_11"/>
    <dbReference type="OMA" id="TIFIHEC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="165" mass="18241" checksum="C5A09B4E68411477" modified="2009-10-13" version="1">MQAIRYTGRMLGKTYDSQVCSIARALEVVGERWSLLIVRDALFGGATRYSDFQRSLGIATNVLKTRLDGLVETGVMRRHQYSQQREQYEYLLTDKGRALAHSLVALSEWGDQWATDGEPPILYVHSVCGTGVTQKTVCAHCGVVEDPAEIRAEIGPGMPADRIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVJ4</accession>
    <name>C7PVJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_0398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784645.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0398"/>
    <dbReference type="ESTHER" id="catad-c7pvj4">
        <property type="family name" value="Proline_iminopeptidase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69350">
        <property type="protein sequence ID" value="ACU69350"/>
        <property type="gene ID" value="Caci_0398"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0398"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024518_2_0_11"/>
    <dbReference type="OMA" id="AHYARYP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="40"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU69350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="47652" checksum="B9407A2E8A76B1CB" modified="2009-10-13" version="1">MPPAIRQTDHLFTVPLHHDRPRGEQIELYAREVTADETLPWLVFLQGGPGHRSPRPLPAALATGWLSRALQDYRVLLLDQRGTGRSTPATRQTLPSRGDARRQAEYLTAFRADSIVRDAELVRRQLTGGAPWSVLGQSFGGFCTISYLSDAPEGLAEVFITGGVPTLEGDADDVYRAAYPRMEDKNALLYHRYPQDVDIARSIAEFLREHETVLPDGTLLTVEAFQSLGIMLGATDGVDRLHYLLEDPFCQTAHRTELSDRFQWQVQAALSFAERPLYALLHEAIYAQGSGPTAWAASRVRKQFPRFDAERVLSETGTPLLFTGETIHPWHFRTDPALRPLRAVADLLAGYEDWRPLYDTSVLAANTVPTFATVYTDDLYVDPKQSLTTADAIRALTVHVSDDHEHDGLTASGTDVLDHLLGMARDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVX3</accession>
    <name>C7PVX3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786658.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2447"/>
    <dbReference type="EnsemblBacteria" id="ACU71365">
        <property type="protein sequence ID" value="ACU71365"/>
        <property type="gene ID" value="Caci_2447"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2447"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074078_2_0_11"/>
    <dbReference type="OMA" id="EQHDIVA"/>
    <dbReference type="OrthoDB" id="1635544at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007995">
        <property type="entry name" value="DUF742"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36221">
        <property type="entry name" value="PTHR36221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05331">
        <property type="entry name" value="DUF742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="141" mass="15090" checksum="C72A19A035D7F92A" modified="2009-10-13" version="1">MTEPGGAGPAEQEHSDTVEPVSAVRPFLLTEGRVVGEEQALPMETQLVSTPEALAQLEEAHLAFERRAIIETCRVPVSLAELAARLRLHLNVARVLVGDLHTRGLLTVHVPRAAGSSDLDILRRVIDGLRAIHTSGGPGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW39</accession>
    <name>C7PW39_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulatory protein TetR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793016.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4423"/>
    <dbReference type="EnsemblBacteria" id="ACU73287">
        <property type="protein sequence ID" value="ACU73287"/>
        <property type="gene ID" value="Caci_4423"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4423"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_0_11"/>
    <dbReference type="OMA" id="FEDTTAN"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24540" checksum="C2A460F3D419F033" modified="2009-10-13" version="1">MRADARRNRERLMTSARDVFVERGPEASLEEIARRADVGIATLYRHFVDRGSLMHAVVLHALTSTAEVVERARREHADPMDALAAYIHAVIALRTSAVVPALLEAVDLDEPQIKQARTTVARLIEELLDEARKAGRLREDAAFADIGLLVVRFSQPLPGRFSEEAQLALAHRHADLLIAGLRADPAQAPLSGPTLHLADLQRLLLFDEDDRAGEKTNAGNDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWG7</accession>
    <name>C7PWG7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_6393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794976.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6393"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75247">
        <property type="protein sequence ID" value="ACU75247"/>
        <property type="gene ID" value="Caci_6393"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6393"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_27_6_11"/>
    <dbReference type="OMA" id="DFMHFHR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="4">
        <location>
            <begin position="34"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="3">
        <location>
            <begin position="217"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU75247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="391" mass="42014" checksum="F2C383C6BBDFDAD6" modified="2009-10-13" version="1">MTEQSPPEHITAASISGKRRRIVQVTPNYPPLLGGLERVVQILATRLAARNDVRVITTDNKAGGAPHRAVEKGGVRVRRHRALTVAHTSLAPGMFGSLLRIERGTVIHLHCATAVVPEQVWLSARLRGLRYLLHFHMEVDASGPLGRLLPLYKTHLFGRVVRGAAGVIVLTESQRGFLAERYGVDPAKVYVVPNGVAEEYFLPPRTPGVEPAAGSAPDPLRLLFVGRLDIQKNVARLLDALALVAEPVRLRLVGDGDLRQDLQAQAARLGLDDRVEFAGRKHGEDLVKEYADAELFVLPSDREGMALVVLEAMAAGLPVLATAVPGNIETVEGVGVLVAPTPQAMAAAIDTLARDRSALAAPAAAGRARVADSRWDQVVAAIEDVYEQVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWM3</accession>
    <name>C7PWM3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75303">
        <property type="protein sequence ID" value="ACU75303"/>
        <property type="gene ID" value="Caci_6451"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6451"/>
    <dbReference type="eggNOG" id="ENOG502ZXX0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1173754_0_0_11"/>
    <dbReference type="OMA" id="RARRIMT"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="25379" checksum="5E8AF925B6FA45AC" modified="2009-10-13" version="1">MAKFLGIGLENLAELADVIVDDLDEVQKGIGWWSSYTDLGTKERGPADDFSPVRVTTHFCGALRALASALDCLGGCLVGVPGLPTDIVKAALSSARDQLTKAAKSNVRQAQLASDLNAITAAAGPAGWMEWLIAMRNTDVHRARRIMTWDIDIGAGNLVEGINMKLPRSPELTEIQACVYAGGTVPTHFEALADAFLDDLTESVVTYLDGAANLLKDLWVERKQTTALIEQPASQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWM7</accession>
    <name>C7PWM7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_6456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795036.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU75307">
        <property type="protein sequence ID" value="ACU75307"/>
        <property type="gene ID" value="Caci_6456"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6456"/>
    <dbReference type="eggNOG" id="ENOG5032YK0">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1934056_0_0_11"/>
    <dbReference type="OrthoDB" id="1811492at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009374">
        <property type="term" value="F:biotin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036896">
        <property type="entry name" value="Avidin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005468">
        <property type="entry name" value="Avidin/str"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01382">
        <property type="entry name" value="Avidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50876">
        <property type="entry name" value="SSF50876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51326">
        <property type="entry name" value="AVIDIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0964">Secreted</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13300" checksum="F05A9270F70A5D6E" modified="2009-10-13" version="1">MWVGTWHNQYGSRLTITDESDHRIQGSFRTALGDSAFAGEEAEISGIHQGECITFNFSTSSATGESICSFTGLLREGKLQTLWHVVSDSAVKPPAPGEQAQLMKLPWAHAVLTNADTFTRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWS4</accession>
    <name>C7PWS4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8358</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796906.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8358"/>
    <dbReference type="EnsemblBacteria" id="ACU77181">
        <property type="protein sequence ID" value="ACU77181"/>
        <property type="gene ID" value="Caci_8358"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8358"/>
    <dbReference type="eggNOG" id="ENOG502Z8QX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071594_0_0_11"/>
    <dbReference type="OMA" id="WQLPVRR"/>
    <dbReference type="OrthoDB" id="1643154at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="247" mass="27408" checksum="2929DF3BAD864938" modified="2009-10-13" version="1">MPEVPLDFPREWVEFNDPDNAAQLYRADLTWLCSRWTCIWGAGCGGIRPGRASDGCCTLGAHYSDKADRKRVEKASERLTDETWQFRSVGLELGITQKDEDGDKQTRVVEGACIFLNRPGFAGGEGCSLHALALREDVHPLTTKPDVCWQLPVRRSYDRVERPDGTEVLVVSIGEYDRRGWGGGGHDLNWWCTGATEAHVGREPVYVSYGPELTEMMGEKAYEVLVGLCEARDASRVLVAPHPADPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWT1</accession>
    <name>C7PWT1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8365"/>
    <dbReference type="EnsemblBacteria" id="ACU77188">
        <property type="protein sequence ID" value="ACU77188"/>
        <property type="gene ID" value="Caci_8365"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8365"/>
    <dbReference type="HOGENOM" id="CLU_1057376_0_0_11"/>
    <dbReference type="OMA" id="PEIYWRR"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982554" evidence="2">
        <location>
            <begin position="24"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="261" mass="24069" checksum="95C05C66BE1F7AC4" modified="2009-10-13" version="1">MLALLLYACSGSGSGKKQPSAHGSSSGPVASQSSVPGTGGSSTQTAANGGASGGASSSSAGAPSGSNGGTASATGSNGGTGGTGGTGGTGGTGGTGGANGTTGGTAGTGPATGGASGASGPSGTNGPGCQLNLSLTSQAAAYANGVDPQFTVAVVNKGTADCDVDVSPKSLVLNVYSGRDHVWSSADCATGGPDVRGIAPGAVQTVTYTWDRTRSAAGCTHPNGSAALGTYYSVVSLGAGSGPNAPAAQSQPKTFELKTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWU5</accession>
    <name>C7PWU5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ordered locus">Caci_8379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796927.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8379"/>
    <dbReference type="EnsemblBacteria" id="ACU77202">
        <property type="protein sequence ID" value="ACU77202"/>
        <property type="gene ID" value="Caci_8379"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8379"/>
    <dbReference type="eggNOG" id="COG1521">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066627_1_0_11"/>
    <dbReference type="OMA" id="HEPWLTL"/>
    <dbReference type="OrthoDB" id="2039419at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU77202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="27989" checksum="E3F23E493D6B5E47" modified="2009-10-13" version="1">MLLTIDVGNTQTVYGLFEGEEIVDHWRVATDPRRTSDELSVMTQGLLSQHSTAGKPGGLTGLSICSTVPSVLHEMRDMSKRHYGDVPTVMVEPGVKTGVPILVDNPKEVGADRIMNALAAHYLYDGPVIVVDFGTATSFDAVSAKGEFLGGAIAPGIEISVEALGMRGAQLRKIELTKPRSIIGKNTVECMQSGILYGFAGQVDGVVHRMAEEMAEDPDDVTVVATGGLAALVLDESEVVDVHEPWLTLVGLRLVYERNSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXN3</accession>
    <name>C7PXN3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786779.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71486">
        <property type="protein sequence ID" value="ACU71486"/>
        <property type="gene ID" value="Caci_2568"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2568"/>
    <dbReference type="HOGENOM" id="CLU_2768235_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="69" mass="7551" checksum="B74751E765307E30" modified="2009-10-13" version="1" precursor="true">MYAGGLLAALLILGLVLVVTSLAMVISEPRAIKEPRTRENPSDITRRLRAQGTQRGRRRTDSTSDDAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXP8</accession>
    <name>C7PXP8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2583"/>
    <dbReference type="EnsemblBacteria" id="ACU71501">
        <property type="protein sequence ID" value="ACU71501"/>
        <property type="gene ID" value="Caci_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2583"/>
    <dbReference type="eggNOG" id="ENOG5033S0V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_854414_0_0_11"/>
    <dbReference type="OMA" id="TVFVYEE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046102">
        <property type="entry name" value="DUF6039"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19505">
        <property type="entry name" value="DUF6039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="34447" checksum="5DCC8CB5F71AC619" modified="2009-10-13" version="1">MTEGLPAIPPAQHQTSVPPDKLLNSGNAGVIVERTAQLKNGYRSEGRKFARGLAEYINTTQQGVATVFVYEETFGTKDLMHFFIHLESLAAYETLVQMGTRDEEYRSTLTAEQIAAEQGGGAWDKIFVDGGMHETVLIPQFWGMYGTEVDGRLEKESTVYQTDGPISGLPGAREQVALPQEQILHSGNAGIILHRSAMIDYDFRSEGRKFAREAAESINENLPGEATVFVYEEAFGTADRLHWLIHLKDIRSYYRVLELHVKNEKVRDLYFEPRIAAEKGGGTWARMFLPGTMVDVGLTPQHWGMYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXW4</accession>
    <name>C7PXW4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin 2 conserved barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793153.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4562"/>
    <dbReference type="EnsemblBacteria" id="ACU73424">
        <property type="protein sequence ID" value="ACU73424"/>
        <property type="gene ID" value="Caci_4562"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4562"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_6_2_11"/>
    <dbReference type="OMA" id="EIEVFRV"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="40"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="153" mass="16900" checksum="BE024F8B01C76194" modified="2009-10-13" version="1">MSMAYVSQPDQQQKLEWLDGGTLAMLLDGAATDGNLMIGRFDVAEGEAPPYHVHTREDEVFLLIKGTALVWCDDQEYELSEGGVVYLPRRHPHGYRITSKRADLLMINTPAGIEGMFRAVGRDLSTPRPEGFEIKPDPAVSEQYGSAIVGPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXZ9</accession>
    <name>C7PXZ9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bioB</name>
        <name evidence="16" type="ordered locus">Caci_4597</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4597"/>
    <dbReference type="EnsemblBacteria" id="ACU73459">
        <property type="protein sequence ID" value="ACU73459"/>
        <property type="gene ID" value="Caci_4597"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4597"/>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033172_2_1_11"/>
    <dbReference type="OMA" id="ADRFCMG"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="63"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ACU73459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="366" mass="38848" checksum="0F448779AD4F83C5" modified="2009-10-13" version="1">MRTMTQSFAHSTLDALLSDLVSAALDGRAPTREQALALLASPDEDVLDVVAAAGRVRRTYFGNRVKLNYLVNMKSGLCPEDCFYCSQRLGSEAEILKYSWIKTGEAAELAAKAVGAGAKRVCLVASGRGPSDRDVERVADTVAAIKDGTPDVEVCVCLGLLKDGQAARLAAAGADAYSHNLNTAEEKYADICTTHTFADRVSTLQDATAAGLSPCSGAIFGMGESDEDVVSVAFALRDLDPDSVPVNFLIPFEGTPLGGRWDLTPARCLRILALFRFVFPDVEVRLAGGREIHLRTQQPLALHLANAIFLGDYLTSEGAPGADDLAMIADAGFSVEGRQETTLPTARAEQVALRRRGAGTQVAANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYH9</accession>
    <name>C7PYH9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_8478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8478"/>
    <dbReference type="EnsemblBacteria" id="ACU77301">
        <property type="protein sequence ID" value="ACU77301"/>
        <property type="gene ID" value="Caci_8478"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8478"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU77301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="25120" checksum="CC43D028CF5A32EC" modified="2009-10-13" version="1">MRVLVTGLGRRRSRTVSGGLAILGFEVRETDADADPQVAADVVLLDCGVIDNEVLAYCRRLRRRTQAPIIAVTQRVDLQAWLRGHEAGIDDYAVQPFGLQELAARLRLAVAPGRDQPAPVPAGPPRRLTAGPLVVSEDARAVTVHGTRIDLRPKEYQLLVVLMRQLGRAVPREELVAQLWPAGWEGAERSLEVHVASLRAKIALPGLISTVRGVGYRMVTPESFHRLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYW5</accession>
    <name>C7PYW5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Death-on-curing family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784816.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0584"/>
    <dbReference type="EnsemblBacteria" id="ACU69521">
        <property type="protein sequence ID" value="ACU69521"/>
        <property type="gene ID" value="Caci_0584"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0584"/>
    <dbReference type="eggNOG" id="COG3654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115697_5_1_11"/>
    <dbReference type="OMA" id="IIRNHPF"/>
    <dbReference type="OrthoDB" id="1838027at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006440">
        <property type="entry name" value="Doc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39426">
        <property type="entry name" value="PTHR39426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01550">
        <property type="entry name" value="DOC_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="123" mass="13155" checksum="2A27C0C13DD13047" modified="2009-10-13" version="1">MRYLTTADLLAITTAALGPNTPIRDPGMIASAAHRPRTTAFGEDAYPDLHTKAAAILHSILRNHPLVDGNKRLAWVACRTFLAVNGADFTPDEDAAVDFVMRAAASELGDVEAIAAVLREWTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ09</accession>
    <name>C7PZ09_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784860.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0629"/>
    <dbReference type="EnsemblBacteria" id="ACU69565">
        <property type="protein sequence ID" value="ACU69565"/>
        <property type="gene ID" value="Caci_0629"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0629"/>
    <dbReference type="eggNOG" id="COG4691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2050366at2"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arc_DNA-bd_dom"/>
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        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
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        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03869">
        <property type="entry name" value="Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arc" evidence="1">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="79" mass="9010" checksum="C21A6ED2557C0F24" modified="2009-10-13" version="1">MVTIVVRNLDEGVKQRLRVRAAKHGRSMEAEVRSILEESVRERENFGVAIIEAFRKHGGVELDIPPRTEMPRVVDFGPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZN6</accession>
    <name>C7PZN6_CATAD</name>
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        <submittedName>
            <fullName evidence="7">Oxidoreductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4690</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="ACU73551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="Caci_4690"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4690"/>
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    </dbReference>
    <dbReference type="eggNOG" id="COG0673">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_394185_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
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        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="69"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="699" mass="75430" checksum="F57756D4FDCC6681" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZP2</accession>
    <name>C7PZP2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_4696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4696"/>
    <dbReference type="EnsemblBacteria" id="ACU73557">
        <property type="protein sequence ID" value="ACU73557"/>
        <property type="gene ID" value="Caci_4696"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4696"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_0_11"/>
    <dbReference type="OMA" id="HTIIYTA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="116"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU73557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="340" mass="37606" checksum="4F7C2A69866AC882" modified="2009-10-13" version="1">MKHGILISDHEKSGAAGRRRNARNAPVAEAGDGAVGDAATVAKPKWTARRRRVVANLTGWSFAAPATLIILGLTLFPAAWAFLISREHWNGITPARQIGWDNYRLMAQDPDFRSAVNHTVLFTVLYVPVVLVLGMFLAIALNRKIRFIAFYRTALFVPLVVSAAATGILANFVFDQQFGLANNLLRVLHLPQQGFLANRHEVMWVIALIYLWTDLAFSVIVYLAALQDIPTDCLEAARIDGANRWQQFRHVILPSLAPVTVFVGVWETISVLQIFELILTTTHGGPLGASQTIVYFIYNQAFNLSRYGYGSAAAYTLFGATLVITLGLFAYARRSKIEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZY9</accession>
    <name>C7PZY9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger CDGSH-type domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6636</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795211.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6636"/>
    <dbReference type="EnsemblBacteria" id="ACU75482">
        <property type="protein sequence ID" value="ACU75482"/>
        <property type="gene ID" value="Caci_6636"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6636"/>
    <dbReference type="eggNOG" id="COG3369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173940_4_0_11"/>
    <dbReference type="OMA" id="MVAICAC"/>
    <dbReference type="OrthoDB" id="2002590at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="3">
        <location>
            <begin position="11"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="59" mass="6714" checksum="E8CB5ABC6E880780" modified="2009-10-13" version="1">MAERAGPILVQGPVEIRLDDGRTIVSRRPMVALCACRRSRRYPFCDTSHRRRCPAASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0G5</accession>
    <name>C7Q0G5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_8683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797222.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8683"/>
    <dbReference type="EnsemblBacteria" id="ACU77498">
        <property type="protein sequence ID" value="ACU77498"/>
        <property type="gene ID" value="Caci_8683"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8683"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_81_0_11"/>
    <dbReference type="OMA" id="AFQRVFK"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032783">
        <property type="entry name" value="AraC_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12852">
        <property type="entry name" value="Cupin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="215"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU77498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="34294" checksum="6AFC4806AD5F28F5" modified="2009-10-13" version="1">MDTLSDLLRRAGAGDAQVRQLIQRPPWSITYADAPALTVFATLGGQAALRLEDVPSVPPVRLAAGDIALVAHSTRHTISDDLATPPQVLIRDGRKQLLGDPSTHAALEANLAPRTWGDGLPGATTMLRGMFKLRGEAGRRLLAMLPPLVVIPAAPRTGAALDLLAAETTLDEPGQDAVLHRSLDLVLVLALRSWCASLGPADPSWYAALTDPAIGSALDHIHTDPAHHWTVAELAAIAGLSRAAFAARFTQLVGQPPMTYLAGWRMTLAADLLREDAGTTVAAAAQAVGYQDAFAFSVAFKRAKGMSPSRWGRAEAVEAVGEAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0P6</accession>
    <name>C7Q0P6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0111 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784969.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0739"/>
    <dbReference type="EnsemblBacteria" id="ACU69674">
        <property type="protein sequence ID" value="ACU69674"/>
        <property type="gene ID" value="Caci_0739"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0739"/>
    <dbReference type="eggNOG" id="COG1392">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086031_3_0_11"/>
    <dbReference type="OMA" id="LFNGKYD"/>
    <dbReference type="OrthoDB" id="1837604at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="210" mass="23272" checksum="5866B688BC226B4C" modified="2009-10-13" version="1">MKLRLTPRETSFYDLFAEQADHLVVGAGILTELLGAGGPENGAERAKIAERMRAAEHAADDTTHKIYNTLNSSFITPFDREDIYALASTLDDVMDEMEEAVDLVNLYGIQMLPAGVAEQVDTLVRAAELTAMAMRKLRGMKDLTEYWIEVNRLENAADQSYRKLLAHLFSGEYDALTVMKLKEVVDSLEGAADAFEHVANTVESIVVKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0X6</accession>
    <name>C7Q0X6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0819</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785049.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0819"/>
    <dbReference type="EnsemblBacteria" id="ACU69754">
        <property type="protein sequence ID" value="ACU69754"/>
        <property type="gene ID" value="Caci_0819"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0819"/>
    <dbReference type="eggNOG" id="COG0340">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051096_5_0_11"/>
    <dbReference type="OMA" id="AVWKHIE"/>
    <dbReference type="OrthoDB" id="1842956at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="25"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="32102" checksum="3B58CC459A53DB35" modified="2009-10-13" version="1">MTDAEGEGRQSPYTDLDRPPLRELAVNKAVVRPGGLWRRIEVVRETGSTNADVADAARGGEGEGFVLVAEAQSAGRGRLGRTWSAPARSGLFLSVLVRPGDVAPARWGWLPLLAGTAVRTAVEAVSGVPVRLKWPNDLIVVDDADSDDGADSDADSNKDTAAHAYGAARKLGGILVERVETSSGPAAVVGVGLNVSLRRDELPAGHATSLVLEGAKAADRDTVLRSVLREIERWYTDWSVTGGDPMASGLASAYVASCATLGRRVRVELPGGAPVEGEAVGLDGDGRLLVRSGGSERAFGAGDVVHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0Z7</accession>
    <name>C7Q0Z7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase domain protein FMN-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2759"/>
    <dbReference type="EnsemblBacteria" id="ACU71672">
        <property type="protein sequence ID" value="ACU71672"/>
        <property type="gene ID" value="Caci_2759"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2759"/>
    <dbReference type="eggNOG" id="COG1853">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059021_1_3_11"/>
    <dbReference type="OMA" id="FGCFPSG"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="45"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="20125" checksum="97AFE4811BA60574" modified="2009-10-13" version="1">MSVHAQIQIPSVTAPSPIAAPTAQITPTGPTGPTAPTAKELRTMFASFPTGVTAVAVLVDGSPVGLAANSFTSVSLEPALVSVCADLKSSTWPVLRSRPRLGISILAAQHEQACLRLASRSADRFADLDFRASADGAVFVEGAGAWIECSLEAEYPAGDHDILLLRVHDIGADPSVAPLVFHRSGFRNLDEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q146</accession>
    <name>C7Q146_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2811"/>
    <dbReference type="EnsemblBacteria" id="ACU71721">
        <property type="protein sequence ID" value="ACU71721"/>
        <property type="gene ID" value="Caci_2811"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2811"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841153_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="220"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="35254" checksum="0C7695357DF8897A" modified="2009-10-13" version="1">MLKWFGDVFVSMPDPDLGSIHGVYAISLTLGMIVAVVLLIVQAGSVAWTRSGAPMAQALTGLPKAVLASLLTLAVSSQVMAASDDLANWIVSSSGSSMTGFTERLTILLALNTPAGPAIPSVLLLLFGLIGIVVVLTLWLELVLRNAVFCAMVAVAPISAAGQIGSSTAERWRKMAKGGLQLAMVYALVGAIGHACEGVETYLSDPFTIWSRRSIVKDVLNQEPSLDRVFQALADPTRRAMVERLTRGPASVSELAKPLPMSLPAVVQHLQVLEAGGLVRSEKVGRVRTCRIEPIALRAAENWLGAQRTTWESRLDRLGDLLADDHKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q152</accession>
    <name>C7Q152_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787020.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU71727">
        <property type="protein sequence ID" value="ACU71727"/>
        <property type="gene ID" value="Caci_2818"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2818"/>
    <dbReference type="HOGENOM" id="CLU_2092386_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="12558" checksum="2100A965E9CDC576" modified="2009-10-13" version="1" precursor="true">MRHLARRRQQDTDHHEPFARFRRHCIIGLLLAGAAFAAAFFTNMDRRSPGDDSGVLGVEIAAAGVGVVCGTGAIMVGVLTTFTSTRQADELKWAVRLGEDMADVYRLPAARSSGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q171</accession>
    <name>C7Q171_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787039.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2837"/>
    <dbReference type="EnsemblBacteria" id="ACU71746">
        <property type="protein sequence ID" value="ACU71746"/>
        <property type="gene ID" value="Caci_2837"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2837"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_276676_0_0_11"/>
    <dbReference type="OMA" id="NGPVIMQ"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="803"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="872"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="379"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU71746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1149" mass="118710" checksum="FB6045D043FDD049" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q198</accession>
    <name>C7Q198_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787066.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2864"/>
    <dbReference type="EnsemblBacteria" id="ACU71773">
        <property type="protein sequence ID" value="ACU71773"/>
        <property type="gene ID" value="Caci_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2864"/>
    <dbReference type="HOGENOM" id="CLU_2022547_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13631" checksum="0B8255755D010DC9" modified="2009-10-13" version="1">MPKDQINFPETIEHVGRTGDAASGEPMSSGMDGASTWYEPIVNVRWHAAGDDKIGNVQVSLQAPIAAWTQMGDELRKAEEKAVGWEEGWMPEAYSPSLSRSELNRLIRTLRRARDQAYGRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1I6</accession>
    <name>C7Q1I6_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_4854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793444.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4854"/>
    <dbReference type="EnsemblBacteria" id="ACU73715">
        <property type="protein sequence ID" value="ACU73715"/>
        <property type="gene ID" value="Caci_4854"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4854"/>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_2_11"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="3"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU73715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="111" mass="11608" checksum="0466D83F787AC84F" modified="2009-10-13" version="1">MGFTCTAQQSEQQITVTVTGDVDLAAYPALEAEAGVWGGAGTDVVLDCSEVTFMDSMGLRVLVQIWQAVTEAGHSMTLADPSTPVMRVLELAGVGQLFGYADPISGRTSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Q3</accession>
    <name>C7Q1Q3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acyl-D-amino-acid deacylase</fullName>
            <ecNumber evidence="2">3.5.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.81" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795333.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6759"/>
    <dbReference type="EnsemblBacteria" id="ACU75604">
        <property type="protein sequence ID" value="ACU75604"/>
        <property type="gene ID" value="Caci_6759"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6759"/>
    <dbReference type="eggNOG" id="COG3653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016107_2_1_11"/>
    <dbReference type="OMA" id="CLDCHPY"/>
    <dbReference type="OrthoDB" id="1319925at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047420">
        <property type="term" value="F:N-acyl-D-amino-acid deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023100">
        <property type="entry name" value="D-aminoacylase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="50"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="516" mass="53832" checksum="2C134666ABC03658" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1W4</accession>
    <name>C7Q1W4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795393.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6824"/>
    <dbReference type="EnsemblBacteria" id="ACU75665">
        <property type="protein sequence ID" value="ACU75665"/>
        <property type="gene ID" value="Caci_6824"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6824"/>
    <dbReference type="eggNOG" id="COG2230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105789_0_0_11"/>
    <dbReference type="OMA" id="WDQDATA"/>
    <dbReference type="OrthoDB" id="1812981at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="37"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="180" mass="20809" checksum="430249D83C5FB1F3" modified="2009-10-13" version="1">MTITPDTKNWTWVLQRPCPECGFAAGAIAREEVPTLLRANAEAWRRYFAAAGDQDVRTRPEPTKWSPLEYACHVRDCNKVYLRRVWLMLAEDDPQFPNWDQDTTAVEDEYNDQDPDKVFAELVDTAEEVAERFASLTAEQWSRTGHRGDGSDFTVESLARYFVHDPIHHLWDVTGTRYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1Y0</accession>
    <name>C7Q1Y0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6840"/>
    <dbReference type="EnsemblBacteria" id="ACU75681">
        <property type="protein sequence ID" value="ACU75681"/>
        <property type="gene ID" value="Caci_6840"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6840"/>
    <dbReference type="HOGENOM" id="CLU_2258666_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="103" mass="10680" checksum="BD7AF38B4EC3B71E" modified="2009-10-13" version="1">MGNGVAMKAGTKLTLAAGLGAGYVLGTRAGREQYEKMRTAARKVADKPAVRQTANVIQVQAFEITKNTASKGREAVGHVVETVRHRGAGDGGDGEVGTGDDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q218</accession>
    <name>C7Q218_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797279.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8740"/>
    <dbReference type="EnsemblBacteria" id="ACU77555">
        <property type="protein sequence ID" value="ACU77555"/>
        <property type="gene ID" value="Caci_8740"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8740"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_11"/>
    <dbReference type="OMA" id="WGMTEFP"/>
    <dbReference type="OrthoDB" id="1015470at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="12"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="423"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="512" mass="54793" checksum="FBE35EF92CB26C4D" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q233</accession>
    <name>C7Q233_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-dependent synthetase and ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797294.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8755"/>
    <dbReference type="EnsemblBacteria" id="ACU77570">
        <property type="protein sequence ID" value="ACU77570"/>
        <property type="gene ID" value="Caci_8755"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8755"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_11"/>
    <dbReference type="OMA" id="VSGPCVM"/>
    <dbReference type="OrthoDB" id="1015470at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="414"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="502" mass="52871" checksum="72097268A6331410" modified="2009-10-13" version="1">MTFLALAVRKAARDHGSATALVAGRGPLSLSFQQLNAASEAMAARLAVRGVGQGQVAALLLPASLDYVVAYCALAKVGAVTAGVGAHYSPAERQAMLANVRPDVVIGTEELLTGRLPDAQIIPVRQAEDRREFAAGLPMLGREHVRTVPSARSHDDPETIVFTSGTSGLPKGALFGAKQIAAISEADNRAQTAPMPLLVATGLNHVGFMTKLAGHLLAGNRLHILTRWRAREALGLICDEGVPVIGGVAAQVALLLRVPQLASYKTDAIKALIIGGGPSPAELVRQARESFGAAYSIRYSSTESGGLGTLTALDAPDEEVFNTVGRPRAGTEISLRDEGGKQVPVGESGEVWMRSASVMSEYWHDPAATAETLTPDGWLRTGDVGLLDDTGCLRLAGRRDDMFVRGGYNVHPQEVEAVLQEHAAVGQIAVVPRPDAVMGQVGVAFVVPCDPAAPPTVEELRLFAGSRLARHKLPEEVRVVPTLPLTAGQKVDRSALRKRVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q236</accession>
    <name>C7Q236_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8758"/>
    <dbReference type="EnsemblBacteria" id="ACU77573">
        <property type="protein sequence ID" value="ACU77573"/>
        <property type="gene ID" value="Caci_8758"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8758"/>
    <dbReference type="HOGENOM" id="CLU_1599754_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="166" mass="16850" checksum="01C6E52750E2F42F" modified="2009-10-13" version="1">MGESAAVPQVDPADGGDDEPFLALAWAEAIEATELLRSALAALGLAGEIPRLRGDVNVYGRPMVTVGRINPTAARRLAAALSRAAQHQPRIYGQAPPANGDTATCGLSTPGEPNRSLRPPRTATPLNLPVAVPMATVLPMAVPSQATPALGAPPGSSATDSIPLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q243</accession>
    <name>C7Q243_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797304.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8765"/>
    <dbReference type="EnsemblBacteria" id="ACU77580">
        <property type="protein sequence ID" value="ACU77580"/>
        <property type="gene ID" value="Caci_8765"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8765"/>
    <dbReference type="eggNOG" id="ENOG50336IT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1324452_0_0_11"/>
    <dbReference type="OrthoDB" id="1808966at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982799" evidence="1">
        <location>
            <begin position="39"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="207" mass="22361" checksum="E8CA674DE7738B05" modified="2009-10-13" version="1" precursor="true">MSFTESPRRRLGARAVPPSLAAALALFLGVCAAPPAAADDIVDDAPVLVTAAILDGKPIDGIPAGPMVDGGYHVHAHLTLYIDGREQWVPAGVGVTRPLVLDPDRPDPVITAAKAFYWLHTHDESGVIHAEAPTPHGFVLGQFFDLWRQPLSRHEVGPAKGEVTVWVDGKRYDGDPRKIALKDHTMVQLNVGRDVPFVPYDFPAKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q256</accession>
    <name>C7Q256_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional DNA primase/polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797317.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8778"/>
    <dbReference type="EnsemblBacteria" id="ACU77593">
        <property type="protein sequence ID" value="ACU77593"/>
        <property type="gene ID" value="Caci_8778"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8778"/>
    <dbReference type="eggNOG" id="ENOG5033DHD">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092810_1_0_11"/>
    <dbReference type="OMA" id="RGAVQWA"/>
    <dbReference type="OrthoDB" id="1601056at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015330">
        <property type="entry name" value="DNA_primase/pol_bifunc_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09250">
        <property type="entry name" value="Prim-Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00943">
        <property type="entry name" value="Prim-Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prim-Pol" evidence="1">
        <location>
            <begin position="30"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="223" mass="24145" checksum="74179DA7DEF8B247" modified="2009-10-13" version="1">MTVLSLPEGDLAEAGPAATDADPLGLKAAALNYIEERHWDILPGASVLRADGAWRCSCGNTACPALGSHPAHRDWNKQITAQPSRVHSWWEEHPDSAILLPTGRTFDVIDVPEQAGCLALARLERNGAALGPVAATPTRRLYFFVLPGTKKKIPEMLVRAGWGRAQLDLICHGEKGFVVAPPSRMGTGGQVQWARPPGESNRWLPEAAELIPTLAYACGRERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2E7</accession>
    <name>C7Q2E7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0856</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0856"/>
    <dbReference type="EnsemblBacteria" id="ACU69789">
        <property type="protein sequence ID" value="ACU69789"/>
        <property type="gene ID" value="Caci_0856"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0856"/>
    <dbReference type="eggNOG" id="COG1668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069607_0_0_11"/>
    <dbReference type="OMA" id="QPYLFPH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="245" mass="24883" checksum="E89EB018F85E0541" modified="2009-10-13" version="1">MLALVPVLVGVSVRVAGIGAGGGTGMLNEVADNGLFLVFASLALTVPLFLPVAVGVVAADQVAGDAADGTLRTVLAWPVGRTRLLAAKLVAAVAYAVAATCTVALSALATGSVLFPMHDVTLLSGSTIPLEAAFGRAVLIAGVVTCCMAGVAVLGLTISTLTDSPATALAGTIGLIVAAEIAGSIPQLEVLQPWLFSFDWLAFADLLRTPVYWGTISHSLWLQAGYAIVALSLAWARFTSRDLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2J0</accession>
    <name>C7Q2J0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="17">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">murB</name>
        <name evidence="19" type="ordered locus">Caci_0900</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 17">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 17">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 17">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="17"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0900"/>
    <dbReference type="EnsemblBacteria" id="ACU69832">
        <property type="protein sequence ID" value="ACU69832"/>
        <property type="gene ID" value="Caci_0900"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0900"/>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035304_0_1_11"/>
    <dbReference type="OMA" id="MQNIGAY"/>
    <dbReference type="OrthoDB" id="841869at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 17" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 17" id="KW-0132">Cell division</keyword>
    <keyword evidence="12 17" id="KW-0133">Cell shape</keyword>
    <keyword evidence="16 17" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 17" id="KW-0274">FAD</keyword>
    <keyword evidence="9 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 17" id="KW-0521">NADP</keyword>
    <keyword evidence="14 17 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13 17" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="18">
        <location>
            <begin position="31"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" evidence="17">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACU69832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="414" mass="43738" checksum="D87D84629596F512" modified="2009-10-13" version="1">MARPPGPATGSVSLMLEQASAPLAPLTTLRVGGPARRMVTAATEQEIVETVKDCDRRGEPLLILAGGSNLVIGDDGFDGTVLKIASTGVTKQKTCSGLRLGVAAGHDWDAFVAEAVELGAVGVEAMSGIPGSAGATPIQNVGAYGQDVSQSIAWIRALDRETGDIRGMQSRCLEFGYRDSVFKQNPGKYVVLTVWFGFDPPAASETERLSAPIRYAELARAVGVEEGERVPLALVRETVLKLRAAKGMVLNAEDHDTWSAGSFFTNPVLDVDAFDALAARSTMLPPRFPAPNNQVKTSAAWLIEQAGYPKGYGAGPATLSTKHTLALTNRGAAAAADVLGLAREIRDGVRDRFGVELVPEPVFVGAGSVASSIRGETQVSDRSLHSSVFRVNRSHRLNRLRLRACQAIAAAGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2N1</accession>
    <name>C7Q2N1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ordered locus">Caci_0941</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785168.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0941"/>
    <dbReference type="EnsemblBacteria" id="ACU69873">
        <property type="protein sequence ID" value="ACU69873"/>
        <property type="gene ID" value="Caci_0941"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0941"/>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_11"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU69873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="122" mass="13360" checksum="3093249DD18CE9A4" modified="2009-10-13" version="1">MIQQESRLRVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDALPGAGVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVLIKDGGDPRGTRIFGPVGRELREKRYMRIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2P3</accession>
    <name>C7Q2P3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2876"/>
    <dbReference type="EnsemblBacteria" id="ACU71785">
        <property type="protein sequence ID" value="ACU71785"/>
        <property type="gene ID" value="Caci_2876"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2876"/>
    <dbReference type="HOGENOM" id="CLU_3267493_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="41" mass="4336" checksum="0E586145A93A3F8B" modified="2009-10-13" version="1">MYVAEALITAAAAGLTVAIGLGLLKKLKASRTPKPNEIRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2U1</accession>
    <name>C7Q2U1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2924"/>
    <dbReference type="EnsemblBacteria" id="ACU71833">
        <property type="protein sequence ID" value="ACU71833"/>
        <property type="gene ID" value="Caci_2924"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2924"/>
    <dbReference type="eggNOG" id="COG1694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1101337_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd11533">
        <property type="entry name" value="NTP-PPase_Af0060_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044548">
        <property type="entry name" value="AF0060_NTP-PPase_MazG-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="27570" checksum="A5043F127DAED4AF" modified="2009-10-13" version="1">MTTTPDPKTVREIARKHIQSGRAEIDATIVQHFGPGLLGADEYWAWERAVEDERRKAVVTVAVSWPDEEPQEFECEVCTKPITGYPCILCEHEPDPWAAHRCDNCEGVDPGSCVANVGAVVAVAEKPQDERDLFADIADITAWLDSSNPSSKHEDAMRVMKLGEEVGEAIAAYIGLTGQNPRKGVTHTMDDLLKELADVAITALAAMQHFTQDEAETRAHMAAKVRQIISRSAIRTRAGAEAQLANLEGGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q370</accession>
    <name>C7Q370_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cellulase</fullName>
            <ecNumber evidence="9">3.2.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_4946</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793535.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4946"/>
    <dbReference type="CAZy" id="CBM46">
        <property type="family name" value="Carbohydrate-Binding Module Family 46"/>
    </dbReference>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73806">
        <property type="protein sequence ID" value="ACU73806"/>
        <property type="gene ID" value="Caci_4946"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4946"/>
    <dbReference type="eggNOG" id="COG2730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018668_0_1_11"/>
    <dbReference type="OMA" id="WISKMST"/>
    <dbReference type="OrthoDB" id="1395441at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005102">
        <property type="entry name" value="Carbo-bd_X2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040946">
        <property type="entry name" value="CBM46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18448">
        <property type="entry name" value="CBM46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03442">
        <property type="entry name" value="CBM_X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982470" evidence="5">
        <location>
            <begin position="38"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="6">
        <location>
            <begin position="80"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="CBM_X2" evidence="7">
        <location>
            <begin position="392"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="CBM46" evidence="8">
        <location>
            <begin position="477"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU73806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="589" mass="62815" checksum="CB04B5F868DD1617" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q383</accession>
    <name>C7Q383_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4959"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH39">
        <property type="family name" value="Glycoside Hydrolase Family 39"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73819">
        <property type="protein sequence ID" value="ACU73819"/>
        <property type="gene ID" value="Caci_4959"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4959"/>
    <dbReference type="eggNOG" id="COG3533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034726_0_0_11"/>
    <dbReference type="OMA" id="PDIDIFW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982747" evidence="1">
        <location>
            <begin position="39"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="436"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="576" mass="59505" checksum="767EDAF3E574F614" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3J2</accession>
    <name>C7Q3J2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6924"/>
    <dbReference type="EnsemblBacteria" id="ACU75757">
        <property type="protein sequence ID" value="ACU75757"/>
        <property type="gene ID" value="Caci_6924"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6924"/>
    <dbReference type="eggNOG" id="COG1875">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_945801_0_0_11"/>
    <dbReference type="OMA" id="IHADYRE"/>
    <dbReference type="OrthoDB" id="1462986at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="154"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="32873" checksum="6386EE18194D7FB2" modified="2009-10-13" version="1">MSKATTAPPSYIERLCAELGAIHADYREVLSASKIINVDPNRGRSSGLVVFMNPVVWAWAGSDPDLDRERMALLRKVRDWEPRFRLLFPHPTPEVAERLDVHIGRLTRWLIRPKRDKIPGSLTAAAQAIDASVEELLALVKVLPPDAFAVRLTVDTNTLIDNPDVAVHTATLGPRYMVHLLPVVLREIDGLKRAGRTELLRDGAARADRRLKHLRSNGDVLLGVKVAGDVHALFEVVEPRGDQLPSWLDLDVPDDRFVASSLLVQSDHPGSTLFVATSDINLQTKLSQVGLPYVELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3U7</accession>
    <name>C7Q3U7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797429.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8892"/>
    <dbReference type="EnsemblBacteria" id="ACU77705">
        <property type="protein sequence ID" value="ACU77705"/>
        <property type="gene ID" value="Caci_8892"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8892"/>
    <dbReference type="eggNOG" id="COG2334">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065747_0_0_11"/>
    <dbReference type="OMA" id="HYNYWRR"/>
    <dbReference type="OrthoDB" id="1003984at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="70"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="341" mass="37769" checksum="83CF277D506982E5" modified="2009-10-13" version="1">MPEEQLPLPHNRNNAVTRGVWRGEDGLIHKVLTHRRTDAPPQWASSADPRFWNYWRREADVYLSGLPDRLGLGAPKLVELRELPDGDLELLLEDVSGTHGGDLTLEDIAAVAFAMGQAQGSAHLPSEPWFSQGFLADYSTTRPADFSLLEDDSAWSLPLIAAHFPPELRAALVRLHRNRERLLTVMTRLPRTVCHLDLWPNNVIRRPDGAVALLDWAFTGDGAVGEDAGNLVPDSFFDWPLRPDFAEHLPDLVTEAYLDGLKAAGWSGDPRSAVLGIRASAVKYDWLMPWCLQAALEDRHRAYGSGEAVDPHVRYEARAAGLAICARWADEAVELADSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3V3</accession>
    <name>C7Q3V3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797435.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8898"/>
    <dbReference type="EnsemblBacteria" id="ACU77711">
        <property type="protein sequence ID" value="ACU77711"/>
        <property type="gene ID" value="Caci_8898"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8898"/>
    <dbReference type="eggNOG" id="COG4705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070268_0_1_11"/>
    <dbReference type="OMA" id="RREIFYW"/>
    <dbReference type="OrthoDB" id="1466669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007136">
        <property type="entry name" value="DUF347"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03988">
        <property type="entry name" value="DUF347"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="266" mass="28646" checksum="89B68663FFE58252" modified="2009-10-13" version="1">MTTELTGRSSTGSARRGLASATAASKVPEVTLIFWITKILTTGMGETTSDFLNQKWDPKIMVSLSGLVLAGVIWAQFRAPRYSAWMYWSAVVMVSVFGTMCADVLHVAFGVPYAVSTAFFAVALAAIFVLWYRIEGTLSIHSITTPRRELFYWLTVVTTFALGTAVGDLTATTLKLGYFSSGVMFAVLFAVPAVAYKFGLNGIVAFWFAYVVTRPFGASFADWMGVSAKRGGLAWGTGPVSLVLLAIIVALVAVLAVTKMDVARQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W0</accession>
    <name>C7Q3W0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anion-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797442.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8905"/>
    <dbReference type="EnsemblBacteria" id="ACU77718">
        <property type="protein sequence ID" value="ACU77718"/>
        <property type="gene ID" value="Caci_8905"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8905"/>
    <dbReference type="eggNOG" id="COG0003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058953_0_0_11"/>
    <dbReference type="OMA" id="EMPVQET"/>
    <dbReference type="OrthoDB" id="1148570at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="Anion-transp_ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="PTHR10803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArsA_ATPase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="330" mass="34395" checksum="6E5B6EA164C5F5E1" modified="2009-10-13" version="1">MSQPWPPECRLHIVTGKGGTGKTTAAAALALALAEGGGRVLLVEVEGRQGIAQLFDTAPLPYEERSIAIAPGGGEVFALAIDPEQALLEYLDMFYKLGRAGKALKKFGAIDFATTVAPGMRDVLLTGKACEAVRRTAADRPGAAFAYDAVVMDAPPTGRITRFLNVNTEVAGLARVGPVKNQAEAVMRVLTSPQTAVHLTTVLEDMPVQETLDGVEELRAAGLPVGTILVNMVRTAHLAIGKRAVVSTAAEKRVAALLRPYGVETSDTHALAVLGREHAERLALEEVERRALDGAGQPVVELPLIAGGIDLGGLYELAATLSAAAAGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3Y0</accession>
    <name>C7Q3Y0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797462.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77738">
        <property type="protein sequence ID" value="ACU77738"/>
        <property type="gene ID" value="Caci_8925"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8925"/>
    <dbReference type="HOGENOM" id="CLU_2913955_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="61" mass="6885" checksum="923AD1A8AFB6405F" modified="2009-10-13" version="1">MAAEKKEINQHDEQEPIPADAEHSEDKPGREIVVSFVKGAAFALGRKVVDNTDKIWDFFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q406</accession>
    <name>C7Q406_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797488.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8951"/>
    <dbReference type="EnsemblBacteria" id="ACU77764">
        <property type="protein sequence ID" value="ACU77764"/>
        <property type="gene ID" value="Caci_8951"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8951"/>
    <dbReference type="HOGENOM" id="CLU_665139_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="413" mass="45962" checksum="C2CF841024FE8C67" modified="2009-10-13" version="1">MASVRNSDDLAKWWRKRNITILLREVHLFHDHQRCRTCQYLATGHGGLDGEQVQTLRRLHRRLILVEAFARMRTKRVDLAFLPLLPCICILCITAIQLPWHGYARQLGAISIAFTPAYVRALRNAARHALGSGLLWRAFPIRMIAATVYDIAFWGGLPVGVLWWMRTADHHVDFLHTLGWFFPSAALAAIFVEVAERRVAAAVARRTDSLGWTVSRSQAAARKLLSLSVGLQDMSRTPHRTSVQRFSNVIASYGQDFKANFATVTTPPLAARRSQQFAQSRQLGMRIAVALDQASQQMLDTATAKQREEIISRIHTLMASALAGDWSGLPEVAPTNWRTRLRERIRRILPPLTLGSFAITLPHLPGVDQHASSVTGIQVGLLLGAVLTLIGATPETRSAVLDAYQKAEPDRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q544</accession>
    <name>C7Q544_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795541.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6983"/>
    <dbReference type="EnsemblBacteria" id="ACU75813">
        <property type="protein sequence ID" value="ACU75813"/>
        <property type="gene ID" value="Caci_6983"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6983"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OMA" id="DDWRKTN"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="13"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="325" mass="34950" checksum="F056A3022E7CE609" modified="2009-10-13" version="1" precursor="true">MKHIKLGGLDVSRIGLGAMGMSAAYTGAGADDAESLRTVRRALDLGVTLLDTAETYGPFTNEELLGRAVKGRRDEVVLATKFGRISHLHGGARRLDSSPATIRIAVEGSLRRLGTDHIDLYYQHRVDPDTPIEETVAALAELVAEGKIRHIGLSAAGPATIRRAHAVHPIAALQSEYSLWTRDPEAEVLPLTQELGIGFVPFSPLGHGFLTGAIRSTAQLDDNDWRKNNPRFTGENFRHNLRIADEVQAVAAESGATPAQVALAWLLAKADTIAPIPGTKRVSRVEENSAADGIELTAEQTGKLDTLTRALGSTHEEADMRLIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5A7</accession>
    <name>C7Q5A7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795604.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7046"/>
    <dbReference type="EnsemblBacteria" id="ACU75876">
        <property type="protein sequence ID" value="ACU75876"/>
        <property type="gene ID" value="Caci_7046"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7046"/>
    <dbReference type="eggNOG" id="COG0295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151846_0_0_11"/>
    <dbReference type="OMA" id="ARNQVPE"/>
    <dbReference type="OrthoDB" id="2043951at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="109" mass="11496" checksum="DFFA2E95826A4AF4" modified="2009-10-13" version="1">MTDSQLDPENAKLHTLAKAQRARNGAAEGAALRDETGRTYVATTVELPALKLSALQTAVAMAVVSGARALEAAVLVTEEKKFRQEDLDVVADLKGAGAPPRLFLADPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5Y5</accession>
    <name>C7Q5Y5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785376.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1156"/>
    <dbReference type="EnsemblBacteria" id="ACU70082">
        <property type="protein sequence ID" value="ACU70082"/>
        <property type="gene ID" value="Caci_1156"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1156"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_5_0_11"/>
    <dbReference type="OMA" id="NHEALWT"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="33433" checksum="4CBC061FB1BF2BDD" modified="2009-10-13" version="1">MTDPLDLNQLRTFLAVHRSGSFTAAAHLLGLSQSTVTTQIRALETRLGRELFERRARGVAPLPYADGLAAQIASPLDRLSGLTDDADTPATEPVHLAGPAEFLGAVGMGLLAPLIADGIQLRVSTGLTDDLLDELRSGRHDLVISTRRPNSRGLISEPFADEEFVLVAAPVWAERLKDPEYLNGKGLPAALVDVPLLAYDADLPIIRRYWRYVFNEQLTAPTRLTTVPDLRGIRTAAVAGAGWTALPKYLCRAELDANTLTLLHEPDEAPLNTAYLVRRPGGSANPNVALVRHHLLAAAKAWWADHEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q612</accession>
    <name>C7Q612_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger SWIM domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_1184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785403.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1184"/>
    <dbReference type="EnsemblBacteria" id="ACU70109">
        <property type="protein sequence ID" value="ACU70109"/>
        <property type="gene ID" value="Caci_1184"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1184"/>
    <dbReference type="eggNOG" id="COG2345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023622_1_0_11"/>
    <dbReference type="OMA" id="HRELPYD"/>
    <dbReference type="OrthoDB" id="448815at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="397"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="475" mass="50541" checksum="C52A3C61FAD33EA0" modified="2009-10-13" version="1">MTSTAQIYGYVRASSLTPSGLLDLQTSGGTTTAGPTAHPRFFSGFLGEAEPAAAALLGVANIAQARYWRPNLAALRDPVVTCNGDRLRFESFSGCCGVYARLDVLDDGMDGTALDRGTTNVDVNNDLRLALARVRGGDPLKLEVGPEGLEATTFDGTVVERKVPLPARWLRGFAEVQAVTSGYDLRAELGAADAARFLRGLPNAQRGVQWLVPAGRTLRLAASPSPGAICIAGPQRLKELLPLLRFGGKLRVYGPNLARGANPVASVWQLDLPGMRLVLTLSPEITRGFSGEGAVLSALAGDDVIDDAETVSALLAFDARIEPDVLAEQAALPVDRVRAALTQLGTAGRVGYDHADAAYFHRELPYDAERAAKQNPRLRAARDLLDADAVRWDGDIATVTVEDHVQRVRSAADGALSCTCLWYAKYQGSRGPCKHILAADAHRRGERGVTDADSETGRETDSSTSAIEETAVTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6D9</accession>
    <name>C7Q6D9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787438.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3238"/>
    <dbReference type="EnsemblBacteria" id="ACU72145">
        <property type="protein sequence ID" value="ACU72145"/>
        <property type="gene ID" value="Caci_3238"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3238"/>
    <dbReference type="eggNOG" id="COG1476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127701_0_0_11"/>
    <dbReference type="OMA" id="HSHEEVA"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="17020" checksum="3D58200536DF0FD4" modified="2009-10-13" version="1">MAHDGPGGRRTLAEKIDILFQTVRRPNRELFSNDEVATACREATGESFSATYLWQLRTGRRDNPTMRHLEALAQFFEVPVAYFFDDDQSSAIARELELLGVLRDAGVRNVALRALTLSPEGIDTLNDMIDVLVRHEEKARTAQQGKGGSEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6J0</accession>
    <name>C7Q6J0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5166</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793754.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5166"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="CAZy" id="GH79">
        <property type="family name" value="Glycoside Hydrolase Family 79"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74025">
        <property type="protein sequence ID" value="ACU74025"/>
        <property type="gene ID" value="Caci_5166"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5166"/>
    <dbReference type="eggNOG" id="COG3534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030937_0_0_11"/>
    <dbReference type="OMA" id="YRMTEGN"/>
    <dbReference type="OrthoDB" id="1303824at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982571" evidence="2">
        <location>
            <begin position="35"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="509"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="642" mass="64667" checksum="0D08F9D06C9820A7" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6N5</accession>
    <name>C7Q6N5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793799.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5211"/>
    <dbReference type="EnsemblBacteria" id="ACU74070">
        <property type="protein sequence ID" value="ACU74070"/>
        <property type="gene ID" value="Caci_5211"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5211"/>
    <dbReference type="eggNOG" id="COG1470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045984_1_0_11"/>
    <dbReference type="OMA" id="WETIVEF"/>
    <dbReference type="OrthoDB" id="1022097at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3048" evidence="2">
        <location>
            <begin position="85"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="3">
        <location>
            <begin position="238"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="37219" checksum="BF7CB775E377A0FC" modified="2009-10-13" version="1" precursor="true">MRLTPRPRARTRVRTRVSTRTRIRTRTRATALITCTAALCLTATACGHSPKKPAARTAPTGTPAASSPANAVSPLTGLPGPTGKILAAKIDNIAYARPQTGLAAADVVYAIEVEGGLSRFLAVYDSDHLPAGKIGPIRSARESDLPILEQYGKVDFAYSGALSVFLPVLASANIVNTSPDQDGAAFSRDSARSAPYNEYLNPAKVLADFPTTAAAKDIGFRFGAAPAGGIPTASLTARMPSASFTFTWDASRGEYLIAMDGHAASTTDGGPLCAPTIVLQKVAETTSPRGFHDVPDQLSPYAPTVGTGKAVVLRDGDSYTGTWSRPTDASPTSFTFDGQPMTFHPGQVWIVLTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V2</accession>
    <name>C7Q6V2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795693.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7135"/>
    <dbReference type="EnsemblBacteria" id="ACU75965">
        <property type="protein sequence ID" value="ACU75965"/>
        <property type="gene ID" value="Caci_7135"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7135"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OMA" id="IRCNSVM"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="25896" checksum="757B6DBFF2BA4F45" modified="2009-10-13" version="1">MSGRLQGKRALVTGSTSNIGRAIAEAFAAEGAHVIVSGRDTTRGAEVVDGIRAKGGRADFARADLDGSPEASRALAEEAEALLGDGIDILVNNAGIYPPGTTVSTDEATFDRVYAVNVKAPFFLTQEIAPQMAAAGGGTIINLGSWVARLAVPVGALYASTKGAMETLTRAWAAEFGPRGVRVNAVSPGVILEPTPGQAHPGEVMVNGTPAGRLGKPQYIADAVVYLASDEASYLHGTVLDVDGGRTAAAVIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V4</accession>
    <name>C7Q6V4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7137"/>
    <dbReference type="EnsemblBacteria" id="ACU75967">
        <property type="protein sequence ID" value="ACU75967"/>
        <property type="gene ID" value="Caci_7137"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7137"/>
    <dbReference type="eggNOG" id="COG2159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_2_0_11"/>
    <dbReference type="OMA" id="TTNYKAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="29"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="37638" checksum="E609CB4F0BD32DF2" modified="2009-10-13" version="1">MRGFVRTAVVPGFWDAGWRGAGQPGGMRVDVHAHLFPAAYLDLLDDFRQDGGVGTREVRALGGGDGERELRLRLAAMDAVGVDVQLLSTCPQGPYTGDPTAAVEAARCANVALAQTVAQYPERLRALAALPLPHILASVDELNRAMEQDGMLGAAVGTSILGRPLSHPDFEPLFAALNRRKGVLFVHPIGESAGSPLMQASKLDRVIGYAAEVSTAILQLFQAGLTVKYPDIRIIAPHMGGYLPFLIQRLDRHRDWYLPKDAPSAGQLMRGIAYDTANPLPAALRLTAEVVGPERLLLGTDYPFEQGPSLRDHIEYILAAGLPEAQAKMIVDVNAADFLDMRSGAEQPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6V6</accession>
    <name>C7Q6V6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7140"/>
    <dbReference type="EnsemblBacteria" id="ACU75969">
        <property type="protein sequence ID" value="ACU75969"/>
        <property type="gene ID" value="Caci_7140"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7140"/>
    <dbReference type="eggNOG" id="COG1961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2192286_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_ribbon_recom" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="108" mass="12498" checksum="A854CE1933BB945C" modified="2009-10-13" version="1">MRRRKHHHYLKGSLWCARCSSRVWYVPGKSHTGEQHFYFMCSGRQKHTCDLPYLKIAQVERAVEDNYTTITLSSDLRIRIAAAMRAAVTDSGTTDSLMRTHSRDSSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q723</accession>
    <name>C7Q723_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ig family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_7207</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7207"/>
    <dbReference type="MEROPS" id="S53.008"/>
    <dbReference type="EnsemblBacteria" id="ACU76036">
        <property type="protein sequence ID" value="ACU76036"/>
        <property type="gene ID" value="Caci_7207"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7207"/>
    <dbReference type="eggNOG" id="COG4934">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012501_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981442" evidence="4">
        <location>
            <begin position="51"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="5">
        <location>
            <begin position="122"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU76036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="710" mass="70868" checksum="A1D9B871BDC50481" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q854</accession>
    <name>C7Q854_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793950.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74221">
        <property type="protein sequence ID" value="ACU74221"/>
        <property type="gene ID" value="Caci_5362"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5362"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035309_1_0_11"/>
    <dbReference type="OMA" id="MSGLHGM"/>
    <dbReference type="OrthoDB" id="1809199at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="403" mass="40605" checksum="EA43326740B6209D" modified="2009-10-13" version="1">MWEKERRSVATVFATHGAVSGTFASRLPWISDHLHLSAGKLGIALLMSSIGAITTMPFAGRAVARYGTRLTARVLIAAFLVVDVLTPWMPSLLALMGCTLLAGAAGGTSDMAMNAQGILVEKRLGRSIMSGLHGSWSTGVLIAALFGSLAAREHLDARVHFAIAGAILSVVMVWGTQGFHTSATDVGLVEDDSESVPLFVIPRGVILLIGLVGFCGIYAEVAAQDWSSVYMHRALHGGEAEAAFTTGMFAFTMAAGRLSGDAVVGRLGATTTVRACGVLGALGGVLVVVAQGPVPAVIGFMLIGVGVSVVVPLAFAAAGHAGPSPTMGVAGVATIAYGAGMAAPGMIGGIADLTSLRVAFCAVAVLAGMVALGGGLLGRNAPTAVHGVPGPRAVEAEALATEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8T8</accession>
    <name>C7Q8T8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1430"/>
    <dbReference type="EnsemblBacteria" id="ACU70353">
        <property type="protein sequence ID" value="ACU70353"/>
        <property type="gene ID" value="Caci_1430"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1430"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_780078_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="355" mass="39864" checksum="DEA4981F1DB7D470" modified="2009-10-13" version="1">MDAEGLRGEQPSVTWHDAPVPPGMPVTQAYVWALDPDDGRVLIQDRGPQHPHRYTLPGGRPEPEDGGDLLQTAAREAMEESQIRIDTERAVYLGHQVVTWFEKRPEPYAQIRYAAPIIAYEPIGPDPDNGRTNRRFMTSLERAPELINWHETGASQAKAALRAGEELGFRVRDPSPEGYRDGEKDRYLVCHDYGMGALWWWVTARNATEIMERVADVVVATSSESIARFADGDLEEVDIDAPDENPLSSLKATRDEQRGKPGFGALVGRGTVYVRQAWDENGDGSLDHYLMELGQDGYRIRQVVEHADGRRVKTDDDDWPFNPPFDLYDPELGLAEVDRAVFEAAWDDAEHETGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q993</accession>
    <name>C7Q993_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5380"/>
    <dbReference type="EnsemblBacteria" id="ACU74239">
        <property type="protein sequence ID" value="ACU74239"/>
        <property type="gene ID" value="Caci_5380"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5380"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_876687_0_0_11"/>
    <dbReference type="OMA" id="IGRSWSG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU74239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="280" mass="29981" checksum="115E10B116887A3A" modified="2009-10-13" version="1">MSRVQLSGAEAMELLQRGEDAADIQDWPVVAACYEEFLTAFPDTPISAELWFDAALANKFLRNWPKAYELGRQAALRAGAAQGHPAWWNLGIAATMVGDWGTAREAWTTYGVPLTPGEGEIEDGFGSALVRLDPGGEAEVVWVRRICPTRARVLSVPYGRRRFGEIVVHDGAPTGERLVEDHAFPVFDELALWQASTAATWRAQVTAPEPLDLTALAGAFEDRGLAMEPVDIAGDADGGALAGARDVLLAAPDEQTATAILAEWAVAGAGRAWHAIHAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9D5</accession>
    <name>C7Q9D5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5422"/>
    <dbReference type="EnsemblBacteria" id="ACU74281">
        <property type="protein sequence ID" value="ACU74281"/>
        <property type="gene ID" value="Caci_5422"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5422"/>
    <dbReference type="eggNOG" id="COG0640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097806_3_2_11"/>
    <dbReference type="OMA" id="CCPPLTE"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018334">
        <property type="entry name" value="ArsR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00846">
        <property type="entry name" value="HTH_ARSR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="112" mass="12129" checksum="C4CC011D4FDBC124" modified="2009-10-13" version="1">MIAEACSTPLVTEPLTDLEAAGLAHVFKALADPVRLRLFSLIASFEGGQACVCDLTPYFDVSQPTISHHLKVLREAGLVDSERRGTWIHYRVRSEALGRLSLLLAPTVTVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QA39</accession>
    <name>C7QA39_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplS</name>
        <name evidence="8" type="ordered locus">Caci_1516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6 7">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785731.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1516"/>
    <dbReference type="EnsemblBacteria" id="ACU70437">
        <property type="protein sequence ID" value="ACU70437"/>
        <property type="gene ID" value="Caci_1516"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1516"/>
    <dbReference type="eggNOG" id="COG0335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103507_2_1_11"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="13613" checksum="6395DAD9566D135F" modified="2009-10-13" version="1">MDKLSNIDELSMRIDVPAFRPGDTVNVHVKVVEGNRSRIQQFKGVVIRRQGSGVRETFTVRKVSFSVGVERTFPLHTPIIEKIEVVTRGDVRRAKLYYLRDLRGKKAKIKEKREAVAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAS5</accession>
    <name>C7QAS5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794127.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5539"/>
    <dbReference type="EnsemblBacteria" id="ACU74398">
        <property type="protein sequence ID" value="ACU74398"/>
        <property type="gene ID" value="Caci_5539"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5539"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_11"/>
    <dbReference type="OMA" id="EVTWTDP"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="390" mass="40796" checksum="D467E178751F8347" modified="2009-10-13" version="1">MLPASALPDTIAVHAGRDDLAALGVHVPPIDLSTTNPLPNVGLGGDSYETLATGGTPISGGSHVYQRLWNPTTARFEEALARMENTQAAVAFASGMAAITACLLAAAAEGKRHVVAVRPLYGGSDHLLASGLLGTEVTWAAADGIAAARRPDTGLVILETPANPTLELLDLARVAEQCGGVPLLVDNTFATPILQKPADFGATLVVHSATKYLGGHGDVLAGVVATTDAWAERLRPIRAITGSVLHPLSSYLLHRGLQTLPLRVRHQSQNAEKLVDRLLANPAVERVHYPGLPECDPQHLIGRQMSGPGAVFAMAVRGGYEAAARVADSVRLITHAVSLGGVDTLIQHPASLTHRPVAADAKPHAAVLRVSVGLEDPEDLYADLERALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB02</accession>
    <name>C7QB02_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="17" type="ordered locus">Caci_5616</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5616"/>
    <dbReference type="EnsemblBacteria" id="ACU74475">
        <property type="protein sequence ID" value="ACU74475"/>
        <property type="gene ID" value="Caci_5616"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5616"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_0_2_11"/>
    <dbReference type="OMA" id="PFEGIIP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="619"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="750"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="994"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="651"/>
            <end position="658"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1052" mass="114202" checksum="E0A4263735C61F83" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>C7QB52</accession>
    <name>C7QB52_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
            <ecNumber evidence="9">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">Caci_7518</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796068.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7518"/>
    <dbReference type="EnsemblBacteria" id="ACU76343">
        <property type="protein sequence ID" value="ACU76343"/>
        <property type="gene ID" value="Caci_7518"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7518"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_11"/>
    <dbReference type="OMA" id="AACHFII"/>
    <dbReference type="OrthoDB" id="955823at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="21"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACU76343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="507" mass="53171" checksum="00DC7F02BFE32FA4" modified="2009-10-13" version="1">MANPASPAAPAARRPVNRVTLYTFGAFGGILFGYDLGVIAGVLVLLAKQWSLTAFQKGAITASLSVGAMVGAMLAGRLSNRAGRRLTIMAAAVVVIIGTVACVLAGGWQVMMLTRGVIGIGIGLSSATVPAYLAELAPARVRGALGSLNQLFIVTGILIAFLVDYALSSHNNWKGMFLGALVPAVILLAGLTILPETPRWLLSKGRDAEARAVLSATLPSATAAELDAEVQDIRDVIRRDSEERGRIRDLWQPWVRPMVLVALILAIGQQFSGVNAINAYFPTMLKSLGFATRTALLSAVVLGVVKFLFTVWELFMVDRWGRRPLLMIGASVMVVSLFAAGLVIKNVTDKDTLGTLTLVFLILYLAGYELGWGATVWVMIGEIFPLRARAAGTAVATTVLWAATGLVTAVFPTMSAKSNLGIGGAMWVFAGVNIVLLLLARFYIPETKGRSLEQIERDLRGGKMSASGAEQTAGATTVPAQAAPAGTGTAAGSATEESGEAGLVSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBQ1</accession>
    <name>C7QBQ1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase, sigma-24 subunit, ECF subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1707</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785922.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1707"/>
    <dbReference type="EnsemblBacteria" id="ACU70628">
        <property type="protein sequence ID" value="ACU70628"/>
        <property type="gene ID" value="Caci_1707"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1707"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_3_0_11"/>
    <dbReference type="OMA" id="TLCATPQ"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="31"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="121"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="195" mass="21203" checksum="4DC1F83D32E241B7" modified="2009-10-13" version="1">MGEPATAWPGERLVRAAQDGDAEAVRALVAGSYPHVLRFARTLCATPQDAEDAAQEAVIILYRRIGMLRATAALGSWMFRIVRNECLRRARVAMRRRDTPWGVDVACDAVEDDVLARLEAEAVVAAIVALPEDLRRVLIMRDVQGWSGRGVAQELGLSVAAMKSRLHRARAMVRAALVSEGTDGTEGTEVAGRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCH6</accession>
    <name>C7QCH6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7615"/>
    <dbReference type="EnsemblBacteria" id="ACU76439">
        <property type="protein sequence ID" value="ACU76439"/>
        <property type="gene ID" value="Caci_7615"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7615"/>
    <dbReference type="eggNOG" id="COG0122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052970_0_0_11"/>
    <dbReference type="OMA" id="EPFRGHR"/>
    <dbReference type="OrthoDB" id="1781735at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="345" mass="38034" checksum="0B1DA0BBB9ADEA83" modified="2009-10-13" version="1">MTDNEDSDIRAVWAARKGRSGGAAFERRRTVPPRRPVVPGARQAPAELVAEAEACATVVVDPGYDLTMTVSALRRGLGDPTFRRAPDNSLWLGCRAPSGEPGTLRLSRVTTETVDAEAWGPGASWLLKTLPDLLGLSDTEETRAEFAELVAAQGNPQLVQSLHRNRGFRVMRSSRVWDSLVPAVLEQRVTVQEAHRAYQLLVRRYGIPAPGAPVDLRLCVSPSPREWALIPSWEWHRAGVDGKRSRAILGASRVAVRLEETVGMERDEAARRIRTVPGIGVWTAAEVMHRAHGDADAVSVGDLHLPRIVCGALGDPAMSWDDERMLELLEPYRGHRYRVSALLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCJ3</accession>
    <name>C7QCJ3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796181.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7632"/>
    <dbReference type="EnsemblBacteria" id="ACU76456">
        <property type="protein sequence ID" value="ACU76456"/>
        <property type="gene ID" value="Caci_7632"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7632"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_753939_0_0_11"/>
    <dbReference type="OrthoDB" id="1591999at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="368" mass="40173" checksum="21D8EC30D314DC37" modified="2009-10-13" version="1">MSSDRSSIDVSIITGGHDVADARLHRLAAALRRAGLAVEVVGLGAPEAGPADCAVRTLGARSAKKRLKADLTLPFKARGKVLLTVDPDMVPGATLARWFKGRKVVADVHEDYLKLLKDRAWARASWKKSAATFAVRICTFWTKRANITVVADDHVPPMKGRRRLVVKNLPDFSFLPQPGDPDTATPRAVYIGDVRRSRGLQAMLAAVEGTYTWELDVVGPVQPGDQAWLDTWHATSSEQVRNRIRFHGRLDPQKAWAVADGAWAGLVLLDDTPAFREAVPSKLYEYLAVGLAVVATPLPRMAELVTASGAGEVVADPAAASATLRRWSEDYDELEKARRNARKWAAEHLTGASPYDTLAEQIRGLVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCZ6</accession>
    <name>C7QCZ6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Low-co2 inducible protein lcib</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1785"/>
    <dbReference type="EnsemblBacteria" id="ACU70706">
        <property type="protein sequence ID" value="ACU70706"/>
        <property type="gene ID" value="Caci_1785"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1785"/>
    <dbReference type="eggNOG" id="ENOG502Z8I9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071940_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040703">
        <property type="entry name" value="LCIB/C_CA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18599">
        <property type="entry name" value="LCIB_C_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LCIB_C_CA" evidence="1">
        <location>
            <begin position="23"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="255" mass="26883" checksum="4B2E9CF89B828A83" modified="2009-10-13" version="1">MDEMSSTSTPASKVLRTTFPTAVPATGFVRATRELLAPHGFHAANTLPLIATCRDELAVTITARLQDAWGAGFNMAGLAGMIVLGRTGVLAASGHAPVEDGVRRFVLVALPHIGIDAQGVIGNVDRPGVPGVSHTCGALMALHDELRGDNAPTGDYPFLDVADPEQGMLRDRIPPFLPDGPLPDLAGLTRIARDVITADTEKVITVLREGQPQPAQVAVFTGIHINGPGGTEYVEPGRCYLDLAPDQPEIELSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD67</accession>
    <name>C7QD67_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792389.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3758"/>
    <dbReference type="EnsemblBacteria" id="ACU72660">
        <property type="protein sequence ID" value="ACU72660"/>
        <property type="gene ID" value="Caci_3758"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3758"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_60_5_11"/>
    <dbReference type="OMA" id="ILWIQGE"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="418" mass="43376" checksum="36FE93EB42067306" modified="2009-10-13" version="1">MRLPVPESGPRRVLAIATAVNMTGYGVYLTASVLYFTRAMGLAASRVGIGLTVAGAVALAAGVPVGHLADRRGARGSYALTLTAAALAMAGLCLTRGFWPFLVFASVAAVAQSTGPAARGPLVKHYGGDRPAEYRAYLRAVTNIGIALGAVLAGFGIQIGTRRAYLLLLAVSAACSAVAAGVVLLLPPLPPEPAGRGRTWIALRDRPYLALTLLDGVMAIQFRVLTAAIPLWLLSRTHAPRWSVSAVMLVNTAIVVVFQVRASRSIDTPKAGGLAFRRSGFAFLASCAIFSTLSGLPAWLTVTLVLAGVVVHTIGEIWQSAGGFELSFALAPSHAVGQYQGLFGMGMGLGVTIGPGLLIALCIDWGTPGWWIVGAMFAVTGLAVPPVVRWSERRLSAPVRQPGRYAGAQSSTSSGPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD80</accession>
    <name>C7QD80_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgB</name>
        <name evidence="12" type="ordered locus">Caci_3771</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3771"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72673">
        <property type="protein sequence ID" value="ACU72673"/>
        <property type="gene ID" value="Caci_3771"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3771"/>
    <dbReference type="eggNOG" id="COG0296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004245_3_2_11"/>
    <dbReference type="OMA" id="FGMKWMM"/>
    <dbReference type="OrthoDB" id="227746at2"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="104"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="614" mass="68339" checksum="944E253B306856D5" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEK6</accession>
    <name>C7QEK6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786190.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1977"/>
    <dbReference type="EnsemblBacteria" id="ACU70897">
        <property type="protein sequence ID" value="ACU70897"/>
        <property type="gene ID" value="Caci_1977"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1977"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003896_4_2_11"/>
    <dbReference type="OMA" id="HWGKVFT"/>
    <dbReference type="OrthoDB" id="482388at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="PTHR43762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="424" mass="44634" checksum="731CFD69E3933B0E" modified="2009-10-13" version="1">MSAMSEQIRNWAGNVLFSPARSHHPASLDEVRQTVAAARSARVLGTGHSFNRIADTDGDLLVLDAMPAEVRIDPDAGTATVPAGMRLADLAAQLHAAGFALTALPSLPHISLAGACATGTHGSGNANQGLAALVRGMQLVGPDGDVVELKRGESADFDGAVVALGALGVVTELTVDVVPTFDVAQFVYEGVAVPQLIAGFDEVFSAGYSVSAFTEWRGEASVWVKAALAPGASEASHPEPGWLGGHLAEHAAHPIPGMSAENCTEQLGVPGPWHERLPHFRPGFTPSSGEELQSEFFLARSRAAEALDAVRELGPLIAPVVQISEVRTVAADALWLSPAYQRDSVTIHFTWVADRAAVEPALAAVEAALLPLGARPHWGKVFLSGPAAALAGYERADDFRKLLARRDPEGKFRNEFVRRLFPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEM2</accession>
    <name>C7QEM2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas1</name>
        <name evidence="10" type="ordered locus">Caci_3904</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792521.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3904"/>
    <dbReference type="EnsemblBacteria" id="ACU72792">
        <property type="protein sequence ID" value="ACU72792"/>
        <property type="gene ID" value="Caci_3904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3904"/>
    <dbReference type="eggNOG" id="COG1518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077904_0_0_11"/>
    <dbReference type="OMA" id="IWVGEAG"/>
    <dbReference type="OrthoDB" id="1581397at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09719">
        <property type="entry name" value="Cas1_I-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033641">
        <property type="entry name" value="Cas1_I-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019851">
        <property type="entry name" value="CRISPR-assoc_Cas1_ECOLI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03638">
        <property type="entry name" value="cas1_ECOLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU72792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="323" mass="35393" checksum="F5A6A0D96FB3D4F3" modified="2009-10-13" version="1">MAGPAQRGSSTPYQLPRIADRVSFVYLERCTVHRDANAITAQDADGITHIPSATIGTLLLGPGTRITHQAMAVLGDCGANVAWVGEHGARFYAAARSLNRSSALVEAQATLWANRRTRLDIARAMYRMRFPDEDPSGFMRQQLLGMEGRRLKDCYRQQSQRTGVPWHGRQYTPGNFNAGDAINQAITAAAQCMYGVAHTIITALGCSPGLGFIHSGHELSFVMDIADLYKTEIGIPVAFDTAAEDSTDIGPRTRRALREQIRTTRLLERCVDDVKALLTTPNNEPGSSDATDTGFFDQVQLQSDRETEVEGGRNYADELGTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QET1</accession>
    <name>C7QET1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792580.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3975"/>
    <dbReference type="EnsemblBacteria" id="ACU72851">
        <property type="protein sequence ID" value="ACU72851"/>
        <property type="gene ID" value="Caci_3975"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3975"/>
    <dbReference type="eggNOG" id="ENOG50332AV">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146762_0_0_11"/>
    <dbReference type="OMA" id="LWRHRIG"/>
    <dbReference type="OrthoDB" id="2009144at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="139" mass="14645" checksum="8BA79D401D1F6F53" modified="2009-10-13" version="1">MPFLPIVLRAVAAAGLAVDAGIHLNLAHRYDPVTSSVISQGTLFRIEAAAAIAAAVLVVLWRRRPGDAFAWLTAAAGLAAILLYRYANPGAIGPLPDMYEPIWYADKVWALISQAAAVATLTPLIIRPHRIGAKAPTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF22</accession>
    <name>C7QF22_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794509.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5922"/>
    <dbReference type="EnsemblBacteria" id="ACU74780">
        <property type="protein sequence ID" value="ACU74780"/>
        <property type="gene ID" value="Caci_5922"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5922"/>
    <dbReference type="eggNOG" id="ENOG5030DSB">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090342_1_0_11"/>
    <dbReference type="OMA" id="ITHTIMI"/>
    <dbReference type="OrthoDB" id="1864489at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025333">
        <property type="entry name" value="DUF4239"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14023">
        <property type="entry name" value="DUF4239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="252" mass="28403" checksum="5ED659A51CEBF80D" modified="2009-10-13" version="1">MTAKDYGIIVAVLILTFITLRLFERFIPHHRREPHNDVAGFIFATVSVVFAVPLAFVVVALWTNNDTAHQTTFKEANELAGIYWISRQLPEPLGPQLEHETLDYAHTVIDDEWPLLADHQTSPKATELVYQMRDSVFAFKPADISQQTLYDHALTHVESLAEERRLRLNQTEESLPPLLWAILIGSALVTIAFTFLFGLSSSFAHTVMVMTLAALVVVSLVVVREMSYPYSGTMKVHPTAFEVFLSRLPAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFY2</accession>
    <name>C7QFY2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_2039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786252.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2039"/>
    <dbReference type="EnsemblBacteria" id="ACU70959">
        <property type="protein sequence ID" value="ACU70959"/>
        <property type="gene ID" value="Caci_2039"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2039"/>
    <dbReference type="eggNOG" id="COG0740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_2_11"/>
    <dbReference type="OMA" id="WIHSPGG"/>
    <dbReference type="OrthoDB" id="1728970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="21912" checksum="2C791D6B83E8A611" modified="2009-10-13" version="1">MADEEKAPQFSWRTREQLFSRRIVVMDGVLDDDNGTLLATQLLSLATEDPEAGISLWIHSPGGSVPAMLAIRDVMRLVPCEVSTLALGLACSAGQFLLSAGAHGRRFALPHSRILMHQGSAGIGGSAVDVEVQADDLRHMVNTVLGLIAADTGQPYDRVFEDSLHDRWFTARQAKDYGFIDHIVDSFAQVVPERKRMGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFZ7</accession>
    <name>C7QFZ7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ricin B lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2054</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786267.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2054"/>
    <dbReference type="CAZy" id="CBM13">
        <property type="family name" value="Carbohydrate-Binding Module Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU70974">
        <property type="protein sequence ID" value="ACU70974"/>
        <property type="gene ID" value="Caci_2054"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2054"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3509">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_595416_0_0_11"/>
    <dbReference type="OMA" id="PIHAGAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="3">
        <location>
            <begin position="321"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU70974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="459" mass="45378" checksum="7CEADBA988481545" modified="2009-10-13" version="1">MDASGYRPGNQSTGRQVRGRSLHDVLHDPGTGIAQQAVIPLDPSRVALIARAILTALAAGTVHGYITPHTIVLTDDGTALLVGDRVAPGATPATDVFALGMALFEAVEGYAPHPAEPLPPMTRAGALGPLIEALTAQDPGRRPTAAAALGLLEAGMAAPASPDATETRTLPQVPAAGATGAPAAGNSADSTATSLLPPVPAGPAMGMAAPPGTSGSSGPPGPPDYSASGYATYDDYPEAKRRALLIGGGLAAVVIIAGVALGVTRPWHQTDTSSSTVPGVPTASSVPTTPVAATPSASVPATPSTPSTTSSTPTPTPTPTPTPTVSNPTALVSMSLCLDAAADGGIHSGAKVTAGTCQGSANQGWQIHTDGTIRSLADANLCLDAAAPNGKVANAAQVAVWNCHGGSNQAWVWNANGTVSPVANTALCLDAAGPVPIHAGANVTAWPCNAGPNEIWAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG25</accession>
    <name>C7QG25_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5-related N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2083"/>
    <dbReference type="EnsemblBacteria" id="ACU71002">
        <property type="protein sequence ID" value="ACU71002"/>
        <property type="gene ID" value="Caci_2083"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2083"/>
    <dbReference type="eggNOG" id="COG0456">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043786_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="121"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="369" mass="39601" checksum="84FEB7D29C3519DD" modified="2009-10-13" version="1">MTRRGVGTRDAGVTRAYGEYVVGGIFGGQHRLHLMRIHRLDLAEAAVYRATAIPVWQAAYAHTLPDVLVPDAAQLLPDAAEGHRTVLGAFEASKDSDSAIAGVSAVSAASAVSAIGVSVINPAKTIAPAFWVAPDRRRRGIGSALLAESLEIVRAAGQAKLLLRVVGGDDSEGFAQARGGRVIERETLSGLDLSTIDRGAFDLWAAPTTTGAGYTLIRWSDHCPEELAESFCDAMTAMADAPGDVSSTPLTVEKLREKEQALVRFGIHRHFQAALAADGQIAGFTNVVTLEKQPGPVEIWNTGVVRAHRGHRLAQRLKAAATLWILDAYPQSTWIFTHNHVANAPMLAVNRRLGYQPIVEWVKVEFPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGA7</accession>
    <name>C7QGA7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4087</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792681.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4087"/>
    <dbReference type="EnsemblBacteria" id="ACU72952">
        <property type="protein sequence ID" value="ACU72952"/>
        <property type="gene ID" value="Caci_4087"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4087"/>
    <dbReference type="eggNOG" id="COG0863">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058045_0_0_11"/>
    <dbReference type="OMA" id="ANIRHAH"/>
    <dbReference type="OrthoDB" id="1071106at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU72952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="34833" checksum="9E39D3ADBC22CBC5" modified="2009-10-13" version="1">MTDSTTTAPTGRTPARSLSGIPTSIWVTAQRNSRAQRTGRYTPDSVAHPAKMLPDIAAYAISTYTQPDDLVVDPMCGIGTTLVEALHLGRRALGVEYEARWAKYAEANIALARAQGAVGTDAKVIRADARKLAKVAPPELLGTAALVITSPPYGAAVHGQIKATAETGEKGVQKFDYRYSTDRGNLAHVGREELVAGFAQILSGCRELLRPGGVVAVTARPWREHGELVDLPSEVIAAGVAAGLQPIERCLALIAGVRDRQLVTRPSFFQLANIRQARAAGVPMHLIVAEDVLLFQAPGPALDGPETEPGRAWKQADGDGGSGEIPEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGE4</accession>
    <name>C7QGE4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792718.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4125"/>
    <dbReference type="EnsemblBacteria" id="ACU72989">
        <property type="protein sequence ID" value="ACU72989"/>
        <property type="gene ID" value="Caci_4125"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4125"/>
    <dbReference type="eggNOG" id="ENOG50346F3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166197_0_0_11"/>
    <dbReference type="OMA" id="TTECHYV"/>
    <dbReference type="OrthoDB" id="1996669at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="116" mass="11730" checksum="31BEE207EBFF1203" modified="2009-10-13" version="1">MSLSAAFESPGVIGAALVDAVTGLAYRASGDFSAVGEAHETAELTTLIAEGLHEAGAAGELESVVVTTSGLHEIVHAVPGRAPLNSVVLVLALERERANLALAVRETASLAESILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGL1</accession>
    <name>C7QGL1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit</fullName>
            <ecNumber evidence="8">2.1.1.132</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_6034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.132" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794620.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6034"/>
    <dbReference type="EnsemblBacteria" id="ACU74891">
        <property type="protein sequence ID" value="ACU74891"/>
        <property type="gene ID" value="Caci_6034"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6034"/>
    <dbReference type="eggNOG" id="COG2241">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031955_1_0_11"/>
    <dbReference type="OMA" id="TKFEVRA"/>
    <dbReference type="OrthoDB" id="1706318at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046025">
        <property type="term" value="F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006365">
        <property type="entry name" value="Cbl_synth_CobL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036428">
        <property type="entry name" value="CobL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02467">
        <property type="entry name" value="CbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU74891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="397" mass="40889" checksum="FAA2F392319B0D6E" modified="2009-10-13" version="1">MPEIAVTVTVIGFDGAPLSDAARSALASATLVVGGERHLDAIELPSGAARYVLGSVDGMFDAMASHANVCVIASGDPGFFGIVRQLRERGLDIKVLPAPSSVATAFAAVGLSWDDAIVVSAHGRELRPVANVCRAFPKVAVLTGPGAGARELGAELPDRTFVVAQRLGHLDQKIETLSSHAAAHSTFADPHVLLCLDESRLTSERGWIAGFGGVPGTWALGESEFAHRASMITKSEVRALALAKLGPRPGRLVWDIGAGSGSVGVECARFGAAVVAVERDAESCDRIRANAAAHGVAVEVMTADAAIALDRLPEPDAVFVGGGGVDVIAACAATPAAMVVVALAAIERVPDAISLLTKFGRDVDGVLLQSSRLSALPGDAHRFAAANPVFLLWGERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7QGS8</accession>
    <name>C7QGS8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">Caci_6103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6103"/>
    <dbReference type="EnsemblBacteria" id="ACU74958">
        <property type="protein sequence ID" value="ACU74958"/>
        <property type="gene ID" value="Caci_6103"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6103"/>
    <dbReference type="eggNOG" id="COG1496">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065784_3_1_11"/>
    <dbReference type="OMA" id="CFADCVP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACU74958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="26160" checksum="5739D6DC64D65DC2" modified="2009-10-13" version="1">MAIWQHTGPDGEGGKARFAFSDRWGGVSKAPYTATNLGGHVGDDPEAVAANRSLVAFELGFTDPGNVVYMNQIHGADVAYAAAQWQGRAPDVDALVTDRRHLALAVLVADCVPVLLADAEAGVVAGAHAGRPGMKAGVVPAAVERMVTLGAAPERIVAVSGPSVCGLCYEVPERMRADVAEKVPASYTVTRQGTPGLDVAEGVWAQLEACGIDLKSSVRLRVCTQESEDYYSFRGEGTTGRFAGFVWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7QH96</accession>
    <name>C7QH96_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_0080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784330.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0080"/>
    <dbReference type="EnsemblBacteria" id="ACU69035">
        <property type="protein sequence ID" value="ACU69035"/>
        <property type="gene ID" value="Caci_0080"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0080"/>
    <dbReference type="eggNOG" id="ENOG5033VU9">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080171_1_0_11"/>
    <dbReference type="OrthoDB" id="1834386at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983225" evidence="3">
        <location>
            <begin position="25"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU69035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="232" mass="23877" checksum="A22A961C377EF877" modified="2009-10-13" version="1" precursor="true">MRNLLGSLLAIIGAAATLVSPWQAWYNNRHGSSYKFYEVFGSGVTLSGSGIMDSVFLVFLITAVLAVAGVVLRSRALVGAAGVIAFGFTILWMVRQGQAAGELTVTGANNRGLGSGVAYAFGGGLLMIIGSLMMTGRTRRTVVAEPARTKTADQAMYGTAATTSAPPAITTTAPADKNPVPPAAAPAATPAQTSASAAPTASERTGTERLSKEERQMLGLDEDASAEPKKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHK1</accession>
    <name>C7QHK1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, DeoR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_2107</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786319.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2107"/>
    <dbReference type="EnsemblBacteria" id="ACU71026">
        <property type="protein sequence ID" value="ACU71026"/>
        <property type="gene ID" value="Caci_2107"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2107"/>
    <dbReference type="eggNOG" id="COG1349">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060699_3_0_11"/>
    <dbReference type="OMA" id="STHEPGF"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU71026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="263" mass="27642" checksum="AC13D636DC9285C4" modified="2009-10-13" version="1">MLAAQRQARILEEVQRTGGVRVNDLTRLLGVSDMTVRRDLDVLDSRGLLTKVHGGATVRRAGSTDEPAFTVKAEMEQPAKDAIARTAAALVRPGTAIGISGGSTTYTLARHLVGVPDLTVVTNSLRVADVLHAHESASPGNNQTVILTGGMRTPSEALVGPIAVQAIRTLHLDQVFLGVYGMDAAAGYTSPNLMESETNRALVAAARNLVVVADHTKWGVVGLSAFAGLGEAAVLVSDDGLPREAREVLVEEVGELVLAERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHN2</accession>
    <name>C7QHN2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786350.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2138"/>
    <dbReference type="EnsemblBacteria" id="ACU71057">
        <property type="protein sequence ID" value="ACU71057"/>
        <property type="gene ID" value="Caci_2138"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2138"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079357_0_0_11"/>
    <dbReference type="OMA" id="YHEVEGG"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="18"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="237" mass="25867" checksum="38FCD3249AD68937" modified="2009-10-13" version="1">MLTVDFEKFPIAKGEKVLDMGCGFGRHAFALLRQGADVVALDYSQDEVAEVTKWFAAMQTAGEVPAGASAIAVRGTAYGLPFADGTFDAVVAAEVLEHLPDDRLAMSELVRVLKPGGRLAVTVPRWFPEKVCWALSDAYHEVEGGHIRIYKRREMIDKLRAAGVVPGELHHAHALHAPYWWLKCAVGVDNENAPVKAYKKLLEWDIIKAPALTRASEALLNPVLGKSLVVYAQKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7QHT6</accession>
    <name>C7QHT6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetoacetyl-CoA synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012786404.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2192"/>
    <dbReference type="EnsemblBacteria" id="ACU71111">
        <property type="protein sequence ID" value="ACU71111"/>
        <property type="gene ID" value="Caci_2192"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2192"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_3_11"/>
    <dbReference type="OMA" id="WYSSTGW"/>
    <dbReference type="OrthoDB" id="141801at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030729">
        <property type="term" value="F:acetoacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="3">
        <location>
            <begin position="45"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="106"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="550"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU71111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="669" mass="72790" checksum="BC59837A1D59B63C" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIE2</accession>
    <name>C7QIE2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794748.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6165"/>
    <dbReference type="EnsemblBacteria" id="ACU75019">
        <property type="protein sequence ID" value="ACU75019"/>
        <property type="gene ID" value="Caci_6165"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6165"/>
    <dbReference type="eggNOG" id="COG3147">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_602299_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="433" mass="46802" checksum="D875008C10C552E6" modified="2009-10-13" version="1">MTTNRGFICGTALVEGEFDAYSEDEFYERRIGSRAAIVPPPPPAPLFGDRPSMEHYERALRHFTDHPDSDGALTHLRDLTVQGLRAGTLTAHDLLFEVRPAAVAVAVLAEPDVAGTGAVLAAVIRAAVGERASRWAYLVDQVALWTGSLSSLLVGRDDTGIGDHLSVPPSPPNVWTGHWWRPANIMLALAPLEDGRRFFTEAIGRTAIRRAGAAQAMAGCMPLSRALVEHTLSPRGRLRARVNLAGNAFTPDVVLAELLNRAGEPAIATAVRAHDFADGELRHQAFLAVRDRPEAVRKSLGELLEHGQRQFLDLLAAVPDDDATWLHTLIKLAGEGMRPDARREAYSRLAAVSGPEVVWSLELARVGSLEAMAPEVRASMAESSAEPLAAAVRERPFRDPEATINAAAAEMRREGALDRPLPWLGSGQAKREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QIJ4</accession>
    <name>C7QIJ4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin 2, barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6217"/>
    <dbReference type="EnsemblBacteria" id="ACU75071">
        <property type="protein sequence ID" value="ACU75071"/>
        <property type="gene ID" value="Caci_6217"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6217"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137310_0_0_11"/>
    <dbReference type="OMA" id="SHVARNG"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983245" evidence="1">
        <location>
            <begin position="44"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="160" mass="16650" checksum="21DFFC296630B369" modified="2009-10-13" version="1" precursor="true">MPLDTPSIAPRVMLRVMSTARRRVALAGAVAATAALAPGVASATAPSGVSVTETSRTSLLGVDHVLRQVTIQPGGSTGWQWHAGTLSVYVEKGSVTHNESDCFSTQVYSDNSSFLEPDGADNVQIDRNLGTTPLVLDILYVSPAGSPLDQDAPNPGCAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJ14</accession>
    <name>C7QJ14_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ordered locus">Caci_0201</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784451.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0201"/>
    <dbReference type="EnsemblBacteria" id="ACU69156">
        <property type="protein sequence ID" value="ACU69156"/>
        <property type="gene ID" value="Caci_0201"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0201"/>
    <dbReference type="eggNOG" id="COG0148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_2_1_11"/>
    <dbReference type="OMA" id="EFMIIPV"/>
    <dbReference type="OrthoDB" id="533698at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="362"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACU69156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="428" mass="45818" checksum="87B51871B42F1F55" modified="2009-10-13" version="1">MASIEAINAREILDSRGNPTVEVEVLLEDGSFARAAVPSGASTGAFEAVELRDGDAARYGGKGVERAVQGVLDEIYPAVVGEDASDQRLIDQAMIDLDATPNKARLGANALLGVSLAVAKAAAESAELPLFRYLGGPNAHTLPVPMMNILNGGAHADSNVDIQEFMIAPIGAGSFREALRWGAEVYHALKSVLKERGLNTGLGDEGGFAPSLPSNRDALDLILVAIEKAGYTPGRDIALALDVAASEFYKDGAYQFEGKSRTASEMTDYYAELVDAYPLVSIEDPLFEDDWDGWKILTDRLGTQVQIVGDDLFVTNPERLARGIAGGQANALLVKVNQIGTLTETFDAVQLAHRNGYRCMMSHRSGETEDTTIADLAVAVDCGQIKTGAPARSDRVAKYNQLLRIEEELDDAARYAGRSAFPRFTHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJP1</accession>
    <name>C7QJP1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_2346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2346"/>
    <dbReference type="EnsemblBacteria" id="ACU71264">
        <property type="protein sequence ID" value="ACU71264"/>
        <property type="gene ID" value="Caci_2346"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2346"/>
    <dbReference type="eggNOG" id="ENOG5033PKP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1178534_0_0_11"/>
    <dbReference type="OrthoDB" id="1390771at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU71264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="235" mass="25943" checksum="946CB609A70FF540" modified="2009-10-13" version="1">MIADTAYIARRLQQLGDWDAALAVLGPDTDPELRAEIAVERWFFRWSGHAEAEQAVAALDQSTPAAHVLRARLAYSRLVFDRDPRPDDRAAAEAGYRDAVCDGDEPIRGWAEFHWGCLLDNVDGDADGAAPHFETALEIGLKHRDPALESIALRHLSAQREPEERIRMLRRSLNLRAALGVRPYIVAAQATLASELAEDDPERAELTELYSAAAEEMGIAWLLGGGTGKTEEFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJW9</accession>
    <name>C7QJW9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YCII-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792936.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4343"/>
    <dbReference type="EnsemblBacteria" id="ACU73207">
        <property type="protein sequence ID" value="ACU73207"/>
        <property type="gene ID" value="Caci_4343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4343"/>
    <dbReference type="eggNOG" id="COG3795">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130902_1_0_11"/>
    <dbReference type="OMA" id="FAEIKEH"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="121" mass="13724" checksum="FE5D509488607C89" modified="2009-10-13" version="1">MKYLLLIYGNEEKWASIATESLDKEIAKQDAWNTRHLASGELLAAYGLGGESEAQLVRRKDGAPFATDGPYLESKEFVCSLYVIDVESPERAREIAAEMPWANVQPIEMWPILHDVFDDRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7QJX2</accession>
    <name>C7QJX2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792939.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4346"/>
    <dbReference type="EnsemblBacteria" id="ACU73210">
        <property type="protein sequence ID" value="ACU73210"/>
        <property type="gene ID" value="Caci_4346"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4346"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_12_3_11"/>
    <dbReference type="OMA" id="YPGDGTQ"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="289" mass="30104" checksum="CA45C38FCBC383D1" modified="2009-10-13" version="1">MRVFVTGASGHIGSAVVPELIAAGHDVVGLARSDAAAATVSAMGAEARRGDLTGLDGLREAARGADAVVHLGFQHDGIASGRFAEVAAQDEQVVHAICGELADTGKAFLGIGTGRVEDLANHPNPRAKVALAIHGYAERGVRTVLVAVPNVTHSGRDRNGFIPQYLRIARQTGVAGYVGDGTNTWSAGHTLDVARVWALAVDKAPAGAQVTGATEAGVPVRTIAESVARHLGIEAVSMSAEQAAEHFQAFPFIAIDVKMPNEATRELLGWEPTHPTLLADLDAGFYFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>C7QK44</accession>
    <name>C7QK44_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6264</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6264"/>
    <dbReference type="EnsemblBacteria" id="ACU75118">
        <property type="protein sequence ID" value="ACU75118"/>
        <property type="gene ID" value="Caci_6264"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6264"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_1_3_11"/>
    <dbReference type="OMA" id="DRWAIAC"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1066" mass="113759" checksum="2F275AE2A9B902B2" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKC3</accession>
    <name>C7QKC3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major facilitator superfamily MFS_1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_6343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794926.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6343"/>
    <dbReference type="EnsemblBacteria" id="ACU75197">
        <property type="protein sequence ID" value="ACU75197"/>
        <property type="gene ID" value="Caci_6343"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6343"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034180_11_2_11"/>
    <dbReference type="OMA" id="TFVMESW"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU75197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="435" mass="45317" checksum="E7215409BDE3EB7E" modified="2009-10-13" version="1">MSTVNAGPVTPPKPPTVRQRTFSSLKVPNYRLYMTGQSISLVGTWMQMTAQSWLVLTLTHSSTALGLVVALQTLPVLLFGPYGGVIADRADKLRLMVVLQSMMGVLALVLGLLTVFGVVRFWEVCALAVLLGTNNAFENSTRQSFVREMVGRDQLRNAITLNSVMVNAARAVGPAVGGVLIAVVGIGICFLLNAASFVAVVTSLLRMDRSALRPSPPTPRARGQLREGLRYAAATPSIAIPLAMMGLVGLLAYEFQVSLPVFVERTFHGGSVAFGFITSAMGIGAVVGGLFTAARGRTGLQPMIIASAGLGVSMLAVAYAPVLALACAVMLLVGWASVSFIAIGNSTIQLTSDPEKRGRMIALWQVAFQGTTPIGGPLVGWVIAVSDPRSGLAVGGVSCLVAGAGGLMLARRVAGRAAPVQPESESESEPAASLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKD3</accession>
    <name>C7QKD3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794936.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6353"/>
    <dbReference type="EnsemblBacteria" id="ACU75207">
        <property type="protein sequence ID" value="ACU75207"/>
        <property type="gene ID" value="Caci_6353"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6353"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025990_0_0_11"/>
    <dbReference type="OMA" id="NAREWIY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006905">
        <property type="entry name" value="Flavin_halogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04820">
        <property type="entry name" value="Trp_halogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="606" mass="67575" checksum="D118163BEE4EBAAC" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>C7QKG8</accession>
    <name>C7QKG8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8244"/>
    <dbReference type="EnsemblBacteria" id="ACU77067">
        <property type="protein sequence ID" value="ACU77067"/>
        <property type="gene ID" value="Caci_8244"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8244"/>
    <dbReference type="HOGENOM" id="CLU_210415_1_2_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="34" mass="3841" checksum="9D789B8046981153" modified="2009-10-13" version="1">MSVQTLFDILLVLVALAVVWFASFTVLRLFKGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVB1</accession>
    <name>C7PVB1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar transporter</fullName>
            <ecNumber evidence="8">1.3.1.74</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_0314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.74" evidence="8"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784562.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0314"/>
    <dbReference type="EnsemblBacteria" id="ACU69267">
        <property type="protein sequence ID" value="ACU69267"/>
        <property type="gene ID" value="Caci_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0314"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_11"/>
    <dbReference type="OMA" id="WAITASF"/>
    <dbReference type="OrthoDB" id="955823at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="29"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU69267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="479" mass="50535" checksum="817F04829F62D7D6" modified="2009-10-13" version="1">MTTRTGRESGPNPPGDSAAARVAPRIVFIAAAAALGGFLFGYDSAVINGAVTGIQHDFNVGSGTTGFVVAAALPGAAAGAIAGGWMADRIGRIRAMQIAAVLFIISGIGSMFAFQPWDLTIWRILGGFAIGIASVIGPAYIAEVSPPAFRGRLTSFQQLAIVLGIAISALVNYLINQWAGGTNTDHLGGLAAWRWMLGAEVIPAILYGVLSTMIPESPRFLVANGEDDRAREVLAEVEGTHANVADRIAEIRDQLAGEVKPKLADLLTPSRKNLLAVVWIGIGLSVLQQFVGINVIFYYSSLLWQSVGIDTSNSLLISMISAAVNIAGTVVAMALVDRIGRRPLLLIGSVGMAVTLGLCAWMFSYGTHANGKTTLPKAQGVTALLGANAYVFFFAMSWGVVVWVLLGEMFPNRIRAVALSVAASAQWLANWLVTVSFPSLSRWSLAGAYSLYAIAAAVSIPFVYYLVRETKGKTLESMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVD9</accession>
    <name>C7PVD9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0342"/>
    <dbReference type="EnsemblBacteria" id="ACU69295">
        <property type="protein sequence ID" value="ACU69295"/>
        <property type="gene ID" value="Caci_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0342"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030803_0_0_11"/>
    <dbReference type="OMA" id="TVSCHHW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="522" mass="57176" checksum="05CAA03B6000E1D4" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7PVR2</accession>
    <name>C7PVR2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2386"/>
    <dbReference type="EnsemblBacteria" id="ACU71304">
        <property type="protein sequence ID" value="ACU71304"/>
        <property type="gene ID" value="Caci_2386"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2386"/>
    <dbReference type="eggNOG" id="COG3694">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071040_1_0_11"/>
    <dbReference type="OMA" id="WDFNERY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="288" mass="31672" checksum="0FF4FE15C961CE9D" modified="2009-10-13" version="1">MAEPRLENRLESGYEKRFDQRTPGTVATYAWTARFWARSAMQYRASMALTMVNSALTASLELLGILVVFGNVKAIGGFSLPEALYLYGTAQAAFYTSDLLFTGTEYLAVRIRMGTFDSLLIRPVGVLPQVFADQFTPRRLAPLVPAYTALAVGLAKAPVHWTLLRVAMVPYTLLVGVAVFGAIWILVGAFQIVAADASEVMNSITYGGQYMTSYPLALYGRNLMLFLTFGLPLAYVNWQPTLYVLDHADPLGTPSFLRFAGPLFAAALWGLALLAWRQALRHHRSTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW22</accession>
    <name>C7PW22_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015792999.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4406"/>
    <dbReference type="EnsemblBacteria" id="ACU73270">
        <property type="protein sequence ID" value="ACU73270"/>
        <property type="gene ID" value="Caci_4406"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4406"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131565_0_1_11"/>
    <dbReference type="OMA" id="TEGNYLC"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="132" mass="14018" checksum="7781A57C1667A37A" modified="2009-10-13" version="1">MPLSAYELRTSIAVSDIDQAVAFYEGKLGLPLIRSGPSARIAGGSRVYASGGGPALNVYQSATAGTTAATLAVWYVDDLDRIVDELTASGVEFTRYEQFEHDARGITPRAGGGRIAWFQDPDGNTFALESDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7PW82</accession>
    <name>C7PW82_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase</fullName>
            <ecNumber evidence="2">3.3.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.3.2.1" evidence="2"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793059.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4467"/>
    <dbReference type="EnsemblBacteria" id="ACU73330">
        <property type="protein sequence ID" value="ACU73330"/>
        <property type="gene ID" value="Caci_4467"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4467"/>
    <dbReference type="eggNOG" id="COG1535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_2_1_11"/>
    <dbReference type="OMA" id="HVGILMT"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016291">
        <property type="entry name" value="Isochorismatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01398">
        <property type="entry name" value="ISCHRISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="201" mass="21834" checksum="4E04859E29AFCD1F" modified="2009-10-13" version="1">MSASGIEPIEPYRLPAEGELPVQRVAWTPEPGRAVLLIHDMREHFLRFFPAGRDPLATLVANTVRLREACAAAGIPVVFAAQPGGEELEPDRAIVPELAPRPGDKVLTKRRHSAFHRTPPADVLWQTGRDQVIVCGVYAHIGCLTSCVEAFSRDVQAFLVADAVADFSPEKHRAALMLAAEVCAMTPTTDQLLRALAEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7PWS1</accession>
    <name>C7PWS1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796903.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8355"/>
    <dbReference type="EnsemblBacteria" id="ACU77178">
        <property type="protein sequence ID" value="ACU77178"/>
        <property type="gene ID" value="Caci_8355"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8355"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_3_4_11"/>
    <dbReference type="OMA" id="LALWWNT"/>
    <dbReference type="OrthoDB" id="1687413at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="44"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="254" mass="28084" checksum="FB285FBBC444180F" modified="2009-10-13" version="1">MAESSKFDTLASAYAKSRPTYPAEIFDAMQELSGRALSGARIADVGAGTGISSRQLRERGAQVTAVDLSEPMLRQLLAGSPGVGAVLGSANALPLRDASVDFVTFAQSWHWVNPDLAVPEVLRVLKPGGALACFWNMPTVDAPWRLGYNDRIRELIGGDPDYGNDSTALDQETRLELGMRRSHLPVRVFETSWSRRVTLEQRITNVMSRSYISDVAPQRLETFLDNERAFLLKHFPDGMVLEEYTTWLGVVSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV6</accession>
    <name>C7PXV6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4554</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793145.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4554"/>
    <dbReference type="EnsemblBacteria" id="ACU73416">
        <property type="protein sequence ID" value="ACU73416"/>
        <property type="gene ID" value="Caci_4554"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4554"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_4_11"/>
    <dbReference type="OMA" id="QTTMALM"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="17"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="393"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="52"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="436"/>
            <end position="443"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="670" mass="70009" checksum="64268C81CDCDDF52" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7PXV9</accession>
    <name>C7PXV9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular solute-binding protein family 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793148.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4557"/>
    <dbReference type="EnsemblBacteria" id="ACU73419">
        <property type="protein sequence ID" value="ACU73419"/>
        <property type="gene ID" value="Caci_4557"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4557"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_9_0_11"/>
    <dbReference type="OMA" id="VPLFHPV"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982663" evidence="1">
        <location>
            <begin position="21"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="94"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="570" mass="60236" checksum="68C7EBE51832014B" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY21</accession>
    <name>C7PY21_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793210.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4620"/>
    <dbReference type="EnsemblBacteria" id="ACU73481">
        <property type="protein sequence ID" value="ACU73481"/>
        <property type="gene ID" value="Caci_4620"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4620"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_528628_0_0_11"/>
    <dbReference type="OMA" id="HENARWI"/>
    <dbReference type="OrthoDB" id="783425at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="515" mass="53658" checksum="23D37CABD0BF3E42" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7PY85</accession>
    <name>C7PY85_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_6527</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6527"/>
    <dbReference type="EnsemblBacteria" id="ACU75375">
        <property type="protein sequence ID" value="ACU75375"/>
        <property type="gene ID" value="Caci_6527"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6527"/>
    <dbReference type="eggNOG" id="COG1277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069607_0_0_11"/>
    <dbReference type="OMA" id="FLPAHWQ"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU75375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="314" mass="32879" checksum="C408950569DE4350" modified="2009-10-13" version="1">MSDEPEIPHASTYQGAHTLLSAAAAPAFALAPSGAAPGFDPRRTLPLRVELRRQLGRRRTQVAFGLLAVLPLILVAAFKFGNPTNDSGRPGTVDLVSLATVGAPNFVAFTLFATSGFGLVVIVALFCGDTVASEANWSSLRYLLVTPVPRSRLLRQKLIVALALSAAAIVVLPIVALAAGWAAFGWAPARSPLGTSLPTAAALTHLAVVVGYLAVSLLFVAAVGFALSTYTDAPLGAVGGTVMLVIVSNILDTVTALGSVRAILPTHYSYAWLDALSPTINWDAMSRGALSSLAYSLVFFTLAWHKFLRKDITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYJ0</accession>
    <name>C7PYJ0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797037.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8489"/>
    <dbReference type="EnsemblBacteria" id="ACU77312">
        <property type="protein sequence ID" value="ACU77312"/>
        <property type="gene ID" value="Caci_8489"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8489"/>
    <dbReference type="eggNOG" id="ENOG5033771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1097077_0_0_11"/>
    <dbReference type="OMA" id="YRFEPRN"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="253" mass="26189" checksum="51D489125B7550ED" modified="2009-10-13" version="1">MRTRDDRATAPSRRDTSLVGVLRRRARAWWLAVPILAVTLLGGYTATHPAPRFRAQAVVEVEAPSVEQAHADNPNPYADQKASLAATAALIAEGLSSGSSAAELHAQGMSAGYSLTPRNSGTTQEPYYWLPRLDITADGPSVPAAGASLRILLGALNADLDDLQNRVGVDAGDRVRTQLLVSPSTTVIPVRKTRALAGVLLIGGGAAALIPGWARREARRRSRGGRQLAIGAGSGAESGAGPEPVGAVGRVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYN6</accession>
    <name>C7PYN6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Monooxygenase FAD-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_8535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8535"/>
    <dbReference type="EnsemblBacteria" id="ACU77358">
        <property type="protein sequence ID" value="ACU77358"/>
        <property type="gene ID" value="Caci_8535"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8535"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="OMA" id="YGYMRIK"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981347" evidence="1">
        <location>
            <begin position="28"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU77358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="384" mass="40423" checksum="9D22A7C381112C1F" modified="2009-10-13" version="1" precursor="true">MRVLIIGGGIAGTAAALALHQAGFAPAIHEAHPDHGEDLGAFLTLASNGMRALGELAAAEPVAHRGFPLTRLRLIDATGTELTNAPLGEPDDPLTRYRCLRRADLAAALQQEVRRRGIPITRGARLSSLTEDAASITATFANGQTATGDLLLGADGLNSTTRSLISPAQPHYAGQRVFYGYTTEATTIANTAASQHPDSITMIRGSKTAFGYACSPSGEIFWFARVSSPPASPDEIATTTPAAWRDYLAPLLRPDTTPAADIVEATPDQLMVTNAVDLPPGMRWHTPRAVLIGDAAHAASPATGQGASMALEDAVILAKALRDTPTTTTALTNFDRLRRPRVEHNIAASAALSAGRPPSGQPPTLTNEELTRQLAWTTPLPVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7PYW6</accession>
    <name>C7PYW6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784817.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0585"/>
    <dbReference type="EnsemblBacteria" id="ACU69522">
        <property type="protein sequence ID" value="ACU69522"/>
        <property type="gene ID" value="Caci_0585"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0585"/>
    <dbReference type="HOGENOM" id="CLU_2859462_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="64" mass="6853" checksum="9C6E66D9E8C9671C" modified="2009-10-13" version="1">MNTIPTGAEPAEEQRRDSGAGADGELVDELQDDPRDDLPDALVLETARRIIASDAAIIHRLGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7PZ84</accession>
    <name>C7PZ84_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2624"/>
    <dbReference type="EnsemblBacteria" id="ACU71541">
        <property type="protein sequence ID" value="ACU71541"/>
        <property type="gene ID" value="Caci_2624"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2624"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="AWDEFLY"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981348" evidence="5">
        <location>
            <begin position="33"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="76"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU71541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30429" checksum="4037AC25AF90D79B" modified="2009-10-13" version="1" precursor="true">MSASLKYRIFIHVAALLVALVILAPFAWMATASITEPTALITRPYHWIPSHLDFSRYKAIFAGHGDDVASAFRASLVNSTIVAVGTVVISMSVGVLGAYAFAMLRFRLRRVTMMVFLTTYMLPPIALLVPLYLIMSSLGLLDSDLGLIIIYCSYVTPFVLWILSNYFSTIPAELEEAARVDGCSRMGALFRIMLPAARPGLFATIMFAFILAWDEFLYALIFTSSSASKTIPVAIADFTGRYSTDFGLVAAGGLIASVPPVLLAVAFQKFVVGGLSAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q012</accession>
    <name>C7Q012_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Penicillin-binding protein transpeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795234.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6659"/>
    <dbReference type="EnsemblBacteria" id="ACU75505">
        <property type="protein sequence ID" value="ACU75505"/>
        <property type="gene ID" value="Caci_6659"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6659"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_658394_0_0_11"/>
    <dbReference type="OMA" id="DYPITND"/>
    <dbReference type="OrthoDB" id="423699at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982736" evidence="2">
        <location>
            <begin position="27"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="142"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="417" mass="41574" checksum="21C4EE3AB246BAF1" modified="2009-10-13" version="1" precursor="true">MSAFSKRAVIITTTVVAVAAGGTAVAVSRSGSGGTHKAGVAADGSPGAPVTTTAASASDAAAAPATPPTSGTPTSAAGTPAPSDSGALGAFADDGTTPLTDFPSMVKFSQALGSGSHIVTTIDPKYQRAAADAVSAKPLSGMVVLQADTGKILAMASNGPADLAYHAARAPGSTFKVVTAEALLRGGMTPNSAAPCPSKDKDYPITNDETSTVNLKATLHWGFVFSCNTSFTGLFDKAADTPVSQESTKYFGLNQPWDLGLGATLYGVVDGVAANVPTAKGQDFAAELFGQGAITMSPLNMASVAATVDAGQFHQPYLVTGTKPTAHAQPLGKTVDSELKSMMRDVVTEGTAHDSFSAVTPAVSAKTGTAQATGGEDSWMIAFQGNIAVACLVEGGGFGDKAAGPEIAAMLNAANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0L1</accession>
    <name>C7Q0L1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredox_DsbH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784934.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69639">
        <property type="protein sequence ID" value="ACU69639"/>
        <property type="gene ID" value="Caci_0704"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0704"/>
    <dbReference type="eggNOG" id="COG1331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014051_4_1_11"/>
    <dbReference type="OMA" id="PFYFGTY"/>
    <dbReference type="OrthoDB" id="854580at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="710" mass="75922" checksum="60530DC945C0E6B7" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0N2</accession>
    <name>C7Q0N2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012784955.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0725"/>
    <dbReference type="EnsemblBacteria" id="ACU69660">
        <property type="protein sequence ID" value="ACU69660"/>
        <property type="gene ID" value="Caci_0725"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0725"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_7_3_11"/>
    <dbReference type="OMA" id="GSYFKEP"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14352" checksum="5AEC3E3F9E59AD6C" modified="2009-10-13" version="1">MASEKTEIRTDGAPAPMPVFSQGVRKGPILQVSGQGGEDPATGDYVAPGDVKAQTKRTLENVKAIVEAGGGTVDDIVMLRVYLTTRDHFGAMNEAYAEFMAANLGVDGVKPSRTTVFVELPKESMLVEIDALAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0T2</accession>
    <name>C7Q0T2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0775"/>
    <dbReference type="EnsemblBacteria" id="ACU69710">
        <property type="protein sequence ID" value="ACU69710"/>
        <property type="gene ID" value="Caci_0775"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0775"/>
    <dbReference type="eggNOG" id="ENOG5032VPW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1232872_0_0_11"/>
    <dbReference type="OMA" id="WIQIADI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="220" mass="25107" checksum="E74C639B3181CAFE" modified="2009-10-13" version="1">MYYVDDSGDPTKGIAVYSWIEVDTAQAPEAMAVWLRFRQQLFETYQIPTDFELHSTNFLAGRGHPSTENKMNQSKTARREIFVAALKLISDLPGVSIGAVHRTSPRRRTGFGEPMTDPFCRLVLGVDRRLFLGDLQGIMVIDGEGDGSCRFYTRLFRSLGLSGQQLIAVPFFQPSYDSQWIQIADIVAYTAYQSVIRRPGREFCWTWYEDYIDPEGPREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q0U5</accession>
    <name>C7Q0U5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_0788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785018.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69723">
        <property type="protein sequence ID" value="ACU69723"/>
        <property type="gene ID" value="Caci_0788"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0788"/>
    <dbReference type="HOGENOM" id="CLU_2521520_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU69723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="84" mass="8478" checksum="2C46320C50AC4CC9" modified="2009-10-13" version="1">MAHGVAKTGLAKSQTTASTTGGTALLLTGTDGSVLHEYFVQRGAVIGSVVITIDDATASQKSTSQDKATLEAMVSLLCAYKGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q154</accession>
    <name>C7Q154_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylyl cyclase CyaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_2820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU71729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787022.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2820"/>
    <dbReference type="EnsemblBacteria" id="ACU71729">
        <property type="protein sequence ID" value="ACU71729"/>
        <property type="gene ID" value="Caci_2820"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2820"/>
    <dbReference type="eggNOG" id="COG1437">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105244_4_0_11"/>
    <dbReference type="OMA" id="EKHCRNY"/>
    <dbReference type="OrthoDB" id="1811356at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07890">
        <property type="entry name" value="CYTH-like_AC_IV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008173">
        <property type="entry name" value="Adenylyl_cyclase_CyaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21028">
        <property type="entry name" value="PTHR21028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00318">
        <property type="entry name" value="cyaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU71729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="187" mass="20414" checksum="42793C166B2692F8" modified="2009-10-13" version="1">MSIEAELKARVGDPQTVRAGLASRADVTQAVYHDTYYDRAGDGFMSGGRELRLRTIETQDSVRHLLTFKAPAVDEASGSKPEFETEVADPEAVAAILEGLGYRPALTFSKRCENFEFEHDGHPMLATLVTVPEIEGTFLEVETVVEQEDGLSAALDAVRGVLHELGINDDDLTTELYTDAVKRSRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1C3</accession>
    <name>C7Q1C3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_4791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793381.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4791"/>
    <dbReference type="EnsemblBacteria" id="ACU73652">
        <property type="protein sequence ID" value="ACU73652"/>
        <property type="gene ID" value="Caci_4791"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4791"/>
    <dbReference type="eggNOG" id="ENOG502Z94V">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031194_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="617" mass="69988" checksum="C760A89DAAFA0330" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q1X8</accession>
    <name>C7Q1X8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_6838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795407.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6838"/>
    <dbReference type="EnsemblBacteria" id="ACU75679">
        <property type="protein sequence ID" value="ACU75679"/>
        <property type="gene ID" value="Caci_6838"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6838"/>
    <dbReference type="eggNOG" id="COG1720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013458_2_1_11"/>
    <dbReference type="OMA" id="DWPLVGI"/>
    <dbReference type="OrthoDB" id="1535774at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU75679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="151" mass="16875" checksum="C4A3C7D1F1EADA6A" modified="2009-10-13" version="1">MTNIIPIGQVVGGRAEPRDDDWGGEQAVIRLDDRFGPEALAGLDAFSHLEVVYQFHLVDPEKVQTGARHPRNNTEWPLVGIFAQRGKNRPNRIGVSRCRLVKVEGRDVHVTGLDAVDGTPVLDLKPYMAEFGPIGEVAQPEWATELMREYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q282</accession>
    <name>C7Q282_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797343.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU77619">
        <property type="protein sequence ID" value="ACU77619"/>
        <property type="gene ID" value="Caci_8806"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8806"/>
    <dbReference type="eggNOG" id="ENOG50327QG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1728974_0_0_11"/>
    <dbReference type="OrthoDB" id="1556232at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="176" mass="19254" checksum="15527ACBF8E8966E" modified="2009-10-13" version="1">MNSSISTTRTAADAAAEPVRLHVDHNAVKRLGNWTSADRFEVRARRGSVVLDLRSAQLPAGELVVDLDLDRALVKLLLPDDAVVDQRDIAWSGSGKVKDSVGQHNARKNKDAEPAADVRRVRLTGRIHSGEVRVARGGVAMLAAMFSREYVEDVKQARREGTWPTVDDPTRAPKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q2B3</accession>
    <name>C7Q2B3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797374.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8837"/>
    <dbReference type="EnsemblBacteria" id="ACU77650">
        <property type="protein sequence ID" value="ACU77650"/>
        <property type="gene ID" value="Caci_8837"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8837"/>
    <dbReference type="eggNOG" id="COG0823">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023724_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007253">
        <property type="entry name" value="Cell_wall-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04122">
        <property type="entry name" value="CW_binding_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980543" evidence="1">
        <location>
            <begin position="34"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="673" mass="66939" checksum="C742D13E3DD9767D" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q346</accession>
    <name>C7Q346_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_4922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793511.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4922"/>
    <dbReference type="EnsemblBacteria" id="ACU73782">
        <property type="protein sequence ID" value="ACU73782"/>
        <property type="gene ID" value="Caci_4922"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4922"/>
    <dbReference type="eggNOG" id="COG1879">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_3_2_11"/>
    <dbReference type="OMA" id="RTEAFNE"/>
    <dbReference type="OrthoDB" id="1378040at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981390" evidence="1">
        <location>
            <begin position="24"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="36"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU73782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="350" mass="36743" checksum="96540D5487399F05" modified="2009-10-13" version="1" precursor="true">MRFRLLAAGTAAVLSVSALTACSSSKNSSGGKAVVGVDYPRSDTDFWNSYIQYTPQFASQLGLSIKTSNSQNDVAKLAANAQAFMAEGVKGVVMAPQDTAAIAPTLSQLAAKKIPVVSVDTRPDTGSVYMVVRADNRAYGTKACQFLGTKLSGKGSVVMLEGDLSSINGRDRTDAFNACMKQSFPGITVYGEATNWDAATAAQKLQTDLTAHPDVKGVYMESSFALSGTLQLLQQKGLMAPPSDPKHVFVVSNDGIPEELKDIAAGKIDATVSQPADLYAKYALFYIQAAVQGKTFKPGPTDHDSTIIQVRAGLLEDQLSAPLVTADGGAYGGIASLKSTDTSLWGNHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q363</accession>
    <name>C7Q363_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73799">
        <property type="protein sequence ID" value="ACU73799"/>
        <property type="gene ID" value="Caci_4939"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4939"/>
    <dbReference type="HOGENOM" id="CLU_3267495_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="41" mass="4347" checksum="30F2C03F651F812B" modified="2009-10-13" version="1">MGLSKRFDERDRLPSAAAGFSQPGSGSPAVVRTAPEEKVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q393</accession>
    <name>C7Q393_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793558.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4969"/>
    <dbReference type="EnsemblBacteria" id="ACU73829">
        <property type="protein sequence ID" value="ACU73829"/>
        <property type="gene ID" value="Caci_4969"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4969"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_11"/>
    <dbReference type="OMA" id="WVFPNQK"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="473" mass="51794" checksum="96279EE8552EB424" modified="2009-10-13" version="1">MPSTRESGLATGAAPVPAAPGGWPLIGHTAAMLRNPLTFINSLADHGDLVRIRFGPVQLVVVCSPDLTRQVLMNDRVFDKGGPLYDRARDLLGDGLGTCRHDEHRRQRRLIQPAFHHSRIPGYAQAMSEQIEAVVGAWEDGHVIDVRSQMQLISARALMATMFSASMPADLLQQAVDDVNVFIAGVYRNTISPAVLNRLPIPANRRYRQAIGRLRSTIADIITERRAHPGDEDDLLSVLQRAELDADDETSADRRRFSDSELCDQVVLFLLAGSESTSTTLAWSFHLVAEHPAIRDRWYAEVDSVVQGAATIEDLPELPLTGHIITECLRLYAPAGMVTRTTMADTELGGYRITAGTSLIISPHLIHHRPEVHQQPEAFDPDRWSAPSGRARPGPTHEGYIPFGAGARRCIGEQFAVTEIALALATIAARWELQPLPGPAIEPSSIFGMHPKGLRMRARARVVPALNPAEQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3A4</accession>
    <name>C7Q3A4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polysaccharide lyase 8 alpha-helical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_4980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4980"/>
    <dbReference type="CAZy" id="PL8">
        <property type="family name" value="Polysaccharide Lyase Family 8"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU73840">
        <property type="protein sequence ID" value="ACU73840"/>
        <property type="gene ID" value="Caci_4980"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4980"/>
    <dbReference type="eggNOG" id="COG5492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004172_4_1_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="PTHR38481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="SSF49863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982476" evidence="2">
        <location>
            <begin position="41"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_N" evidence="5">
        <location>
            <begin position="53"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8" evidence="3">
        <location>
            <begin position="419"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_8_C" evidence="4">
        <location>
            <begin position="684"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU73840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="797" mass="84346" checksum="C03A16054030412A" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3B7</accession>
    <name>C7Q3B7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular solute-binding protein family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_4993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793582.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_4993"/>
    <dbReference type="EnsemblBacteria" id="ACU73853">
        <property type="protein sequence ID" value="ACU73853"/>
        <property type="gene ID" value="Caci_4993"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_4993"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031285_10_1_11"/>
    <dbReference type="OMA" id="VPNDDYV"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982754" evidence="1">
        <location>
            <begin position="40"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU73853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="432" mass="44795" checksum="70D03994E99BB5C9" modified="2009-10-13" version="1" precursor="true">MPTHLPRPRRAVLTAAVAVAALVLAGCGSTKSSGGSAGATGSADDGTTLTLWTRAGTQTQTQALVDAYNASHKNKVKLTAFPNEQYPDKIATSAGAKALPDIFTSDVVFAPNYVSQGLWTDITGDFNTLPFKDAVAPSHVKAATSDGKIYAVPHALDLSVMFYNKALYKQAGLDPNKGPATLQEFADQARAVAKLGGGNHGTYIGGNCGGCVEFTFWPSIWADGGAVMDDAGTKSSIDSSQVQAVFKVYHDLYADGTADPASKQENGTTWLGALQTGKVGIAPGPSSWLPLIRSKGIDVGVAPIPGVRGGSSTFVGGDVAGIASTSSHEKQAWDFLSWTLGDTAQVDVVAKQGQIIARTDLADNRYAAADPAVLSINQVMAKGKTPYALNFNATYNDPQSPWTAALRGALFGDAASALASGQDAITKSLDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3C5</accession>
    <name>C7Q3C5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase C14, caspase catalytic subunit P20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_5001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU73861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793590.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5001"/>
    <dbReference type="EnsemblBacteria" id="ACU73861">
        <property type="protein sequence ID" value="ACU73861"/>
        <property type="gene ID" value="Caci_5001"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5001"/>
    <dbReference type="eggNOG" id="COG3903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_524488_0_0_11"/>
    <dbReference type="OrthoDB" id="1122082at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU73861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="519" mass="55195" checksum="ADB38FAB8683588E" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3J6</accession>
    <name>C7Q3J6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_6928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_6928"/>
    <dbReference type="EnsemblBacteria" id="ACU75761">
        <property type="protein sequence ID" value="ACU75761"/>
        <property type="gene ID" value="Caci_6928"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_6928"/>
    <dbReference type="eggNOG" id="ENOG502Z9RP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1719047_0_0_11"/>
    <dbReference type="OrthoDB" id="1750660at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU75761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="152" mass="16227" checksum="4B1CBACCC8F4BB24" modified="2009-10-13" version="1">MTARRVASVPARTSTATWHAIIDLVAPLQGPARSVLSAATGVCAAIISEEYTRDAPIIIRPASGPQIRIYTVHGEDALEVLQDETPLSVQPLADPQWTLSVPCGVDDIDDFGRVLAGDGRISLRDLTAVAEIDKFAEPQVRGSLTVNLEELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3R8</accession>
    <name>C7Q3R8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_8863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU77676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015797400.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_8863"/>
    <dbReference type="EnsemblBacteria" id="ACU77676">
        <property type="protein sequence ID" value="ACU77676"/>
        <property type="gene ID" value="Caci_8863"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_8863"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_11"/>
    <dbReference type="OMA" id="MAVTSMG"/>
    <dbReference type="OrthoDB" id="1582456at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU77676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="282" mass="30152" checksum="7227944FF829C001" modified="2009-10-13" version="1" precursor="true">MKQQNWLITGVSSGLGRAFAQAALAAGHTVVGTVRSEADLRAFEALEPGRTHGRVLDVTDSGAVLRTVDEVEHDVGPLDVVVANAGYGLEGTFEETPLDEVRRQFEVNVFGAVATLQAALPHMRRRRRGHLMAVTSMGGLAAFPGVSAYCGSKFALEGILESLGKEVAQFGIRVTAIEPGSFRTDWAGRSMVRTDRTIDDYDDLFGPLREARQQASGNQLGNPAKAGEAVVRIASVEKPPSHLVLGSDALRLVGAARSAVDADIRDWEELSRTTDFAEGAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q3W2</accession>
    <name>C7Q3W2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_8907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="Caci_8907"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183720_1_0_11"/>
    <dbReference type="OMA" id="WEYVTVP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025234">
        <property type="entry name" value="DUF4177"/>
    </dbReference>
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        <property type="entry name" value="DUF4177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU77720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="54" mass="6150" checksum="9EEA77A896016DDF" modified="2009-10-13" version="1">MTKWEYATVPLLVHATKQILDTWGQDGWELVQVVPGPNPDQLVAYLKRPKTTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-12-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q464</accession>
    <name>C7Q464_CATAD</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_0996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0996"/>
    <dbReference type="EnsemblBacteria" id="ACU69924">
        <property type="protein sequence ID" value="ACU69924"/>
        <property type="gene ID" value="Caci_0996"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="528" mass="56519" checksum="D99E35E8CE25103B" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q474</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ordered locus">Caci_1006</name>
    </gene>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ACU69934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU69934">
        <property type="protein sequence ID" value="ACU69934"/>
        <property type="gene ID" value="Caci_1006"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1006"/>
    <dbReference type="HOGENOM" id="CLU_1881988_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU69934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="135" mass="14814" checksum="4BF9BF1942B3CDE5" modified="2009-10-13" version="1">MRGRDYGNREEPGSCRSLGHEPDGGHGDDRWHRSDERADSHLNLRADERCREREQEHSRHTDRSERTDRDACAHDRGDGHGVALTRRSASLVGAGRQADLFQPLPTPDDARAGGALPGSASDDDRRPADAGQPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q4S0</accession>
    <name>C7Q4S0_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BFN domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="2" type="ordered locus">Caci_3130</name>
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        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
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                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787332.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3130"/>
    <dbReference type="EnsemblBacteria" id="ACU72039">
        <property type="protein sequence ID" value="ACU72039"/>
        <property type="gene ID" value="Caci_3130"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3130"/>
    <dbReference type="eggNOG" id="COG1259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096111_2_1_11"/>
    <dbReference type="OMA" id="LFKNFAD"/>
    <dbReference type="OrthoDB" id="1594801at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="156" mass="17233" checksum="86E12A9E85803872" modified="2009-10-13" version="1">MNELDVVGVRVEMPSNQTIVLLREVSGERYLPIWIGANEASAIALAQQGVTPPRPLTHDLFRDVLAAFGRQLLEVRITAMRDMVFYAELVFDGGLQVSARPSDAIALALRTGATIYGAEEVLAESSILIPDEQEDEVEVERFREFLDQVSPEDFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5C2</accession>
    <name>C7Q5C2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_7061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU75891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795619.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7061"/>
    <dbReference type="EnsemblBacteria" id="ACU75891">
        <property type="protein sequence ID" value="ACU75891"/>
        <property type="gene ID" value="Caci_7061"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7061"/>
    <dbReference type="HOGENOM" id="CLU_1412918_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025326">
        <property type="entry name" value="DUF4232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14016">
        <property type="entry name" value="DUF4232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982536" evidence="2">
        <location>
            <begin position="31"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU75891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="192" mass="19005" checksum="321EC3A08763C0DB" modified="2009-10-13" version="1" precursor="true">MHRGFLIAVAAVGVLTVQGCGSGTPTTASNASSTPSAFSTSSTPSASSTPSTSASTSTSASSSCAGLDAKMVPLHGAASGTTFADLVVTNHSTTACTLPAQPALAYFSATHKALPVEFSANPDLKPYNLAPGASAAMVVGYGSAADPPCDGAIAFVRVASLAGDLPFSGRTNCVHDTTYEEGWVAGTYSAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q5T3</accession>
    <name>C7Q5T3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785324.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1104"/>
    <dbReference type="EnsemblBacteria" id="ACU70030">
        <property type="protein sequence ID" value="ACU70030"/>
        <property type="gene ID" value="Caci_1104"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1104"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073071_0_0_11"/>
    <dbReference type="OMA" id="SKWGYTY"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="46"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="329" mass="35042" checksum="7DF306E9165218EE" modified="2009-10-13" version="1">MTSKHPDSGRASTAAFGLGLAAVGRPGYINLGRDADLPADRSVEAMRSRAHELLDAAYAAGIRYFDAARSYGRAEEFLGGWLRAHPDIHDVAVGSKWGYTYTADWQIDAPVHEVKEHSVAVFTRQIGETRSLLGDRLNLYQIHSITPDSPALSDVGLHRRLAALAAQGVRIGLSTSGPQQAEAIRAAMRITIGGSRLFECVQATYNLLETSVGPALAEAHEAGWTVVVKEGLANGRLTDAHLAEQDQDDSALSDVAKSAAVGADAVALAAIAAQPWVDIVLSGAATVAQLASNVVAAQVDLTPDQLEQLSALVMPAQEYWTQRSQMAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q649</accession>
    <name>C7Q649_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3146"/>
    <dbReference type="EnsemblBacteria" id="ACU72055">
        <property type="protein sequence ID" value="ACU72055"/>
        <property type="gene ID" value="Caci_3146"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3146"/>
    <dbReference type="eggNOG" id="ENOG5033PZG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_609285_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="449" mass="45683" checksum="1474EECC2554D005" modified="2009-10-13" version="1">MFVIPNSSAMDATAYGGGPGTFVAQIATGSPESIEALVAQRLKQAEQFLALINQARSATQTLSKAWGGNASETAVKKFTDTLNSFEQIVKVIQASSQLLTTSSTLIKAAQTGYTTVVNAVNPTVQALASNWYTYWAAVSLSTSVSATLRAFINGIEAMLSALGGGQLMQEVTEVIKIIGDIEKLIGSGSHGSSVPPAGTFTSPTTTGATNQLKAPPQVASTTGQQVAASGVDPTAAQTLSQYQNTMNSGIGTQFQNGAQTTGTQIPGTQIPGTQIPGTQIPGTQTGAMPTGGGVPYTGGTTVGNGATIPGQIPTANQFPQPQLPNLNQIPQPQYPTTGYQTPVATPTDPNSGWTAVNPPANSDTPVVAHPVTTPPPVQTPPPAQTPPVASTPPATPGQPATPAGDITVTTTYDGVSTTVTMPVGTQTDVTLVDPTNGSQVHEHITAGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q696</accession>
    <name>C7Q696_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Periplasmic solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3195"/>
    <dbReference type="EnsemblBacteria" id="ACU72102">
        <property type="protein sequence ID" value="ACU72102"/>
        <property type="gene ID" value="Caci_3195"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3195"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_0_0_11"/>
    <dbReference type="OMA" id="LTEQMPK"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981434" evidence="1">
        <location>
            <begin position="26"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="309" mass="31909" checksum="536209F96CF56EDC" modified="2009-10-13" version="1" precursor="true">MAGGIAALAVGAALTAGCSTKPATAPVGASAPGGATTKIAVVAAENFWGSIALQLGGTHVTAASIISNPDTDPHSYEATPNDAKLIARARLFIQNGIGYDTSWAPKLVSANPASGRDVLTVGDVVGLKDGDNPHQWYSHDSVDKVIDAITAEYKKLDPADAAYFDTQKQTFETTTLAPYNQLESDIKATYAGTPIGASESIVSPLADTLGLKMATPYSFLKDISEGNDPSVADKTAIDSQIKGKQIKVYVYNSQNSTPDIAAQVAEAKAAGIPVTTVTETLAPAGATFQDWMVAELQGLKSALAQATGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6I8</accession>
    <name>C7Q6I8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793752.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5164"/>
    <dbReference type="EnsemblBacteria" id="ACU74023">
        <property type="protein sequence ID" value="ACU74023"/>
        <property type="gene ID" value="Caci_5164"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5164"/>
    <dbReference type="eggNOG" id="COG3631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136060_0_0_11"/>
    <dbReference type="OMA" id="DLWVSEC"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="134" mass="14868" checksum="69D0AFAEC76F116C" modified="2009-10-13" version="1">MDSEARTKAAIEEHWQASERGDVEAEHALYAEDAILDYPQSGERFRGRATIAAQRGGHPADRHFTVLRITGVRDLWVSECVITYDGVPSYSVSIMQFAGEQVVHETQYFGDAFGAPTWRAAIAEPMPGRDITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q6P4</accession>
    <name>C7Q6P4_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_42 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5220"/>
    <dbReference type="EnsemblBacteria" id="ACU74079">
        <property type="protein sequence ID" value="ACU74079"/>
        <property type="gene ID" value="Caci_5220"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5220"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_382521_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002981437" description="Glyco_hydro_42 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42" evidence="2">
        <location>
            <begin position="56"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="723" mass="74489" checksum="0840DAA9024FFD28" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q777</accession>
    <name>C7Q777_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ca(2+)/H(+) antiporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_1240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785459.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1240"/>
    <dbReference type="EnsemblBacteria" id="ACU70165">
        <property type="protein sequence ID" value="ACU70165"/>
        <property type="gene ID" value="Caci_1240"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1240"/>
    <dbReference type="eggNOG" id="COG0387">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008721_2_1_11"/>
    <dbReference type="OMA" id="VLLMMMY"/>
    <dbReference type="OrthoDB" id="988251at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="PTHR31503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="37"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="220"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="365" mass="37709" checksum="DAE37ED68B93BAF3" modified="2009-10-13" version="1">MTALAERSRVFSRSDLIFLGLAVVTTVGAVVVRSGSVLPFVVSAAAVAVLAALVGRAVDHLADRLGAGAVGVLQSALGNLPELFISIFALRAGLTTVVTSAIIGSILANLLLVLGLSFTVGSARHGVLRFSEQRARLIMGLMILSVASMLIPSLASYIHSPAAGHEVALSRITAIVLLTVFALSIPASLRREAEPRAAEQSAEASEEEGGGNHWPLWLAVGMLAVTGLAAAYVSDLFVDALTPAMNSLHISQAFSGLVIVAIAGNAVENAVGVKLAWQNQADHALSVVLNSPLQIALVLAPALVLLSPVIGGPAFTLVFNPMLVTTVGIATLAVLYLISDGESDWLEGSAMIGLYVLVATAFWWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7H7</accession>
    <name>C7Q7H7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_3263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787463.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3263"/>
    <dbReference type="EnsemblBacteria" id="ACU72170">
        <property type="protein sequence ID" value="ACU72170"/>
        <property type="gene ID" value="Caci_3263"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3263"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075552_0_0_11"/>
    <dbReference type="OMA" id="TITHHAC"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="221"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU72170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="311" mass="33378" checksum="CB337D56BE815BE3" modified="2009-10-13" version="1">MTALTAIGTYLPPERVPIEDMAERFGLTAMQTKVFRRYHKLGAVSRDAGGTLSDLLRGALDDLDGLIGNEERVRYVIHARTFPTVTPYPLNPLRELCRERGLEHAETFAVGHHACASGLLAIDVAGRLLAADAETHPDALALILAGEKAFTGEAQMVPETSFFGEGASACLVSASGERDRLLSYTADLRGEFDGDSMEQALEFQRVYSDALGEAILAAVEGAGLEMSAISLVLPHNVNVVAWQRVCKRIGFPLAKVVLDNVATDGHVFCADAFLNYRTAARKGLLTPGERYVLAAAGAGRGATFSAMVFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q7S1</accession>
    <name>C7Q7S1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787557.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3357"/>
    <dbReference type="EnsemblBacteria" id="ACU72264">
        <property type="protein sequence ID" value="ACU72264"/>
        <property type="gene ID" value="Caci_3357"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3357"/>
    <dbReference type="eggNOG" id="ENOG5031047">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076823_1_0_11"/>
    <dbReference type="OMA" id="CNSTNDL"/>
    <dbReference type="OrthoDB" id="1546331at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PTHR37536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983000" evidence="2">
        <location>
            <begin position="29"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="236" mass="24565" checksum="4F1C6048089AAD72" modified="2009-10-13" version="1" precursor="true">MRRFLIHAAALAAAATSIAPAAPVAASAASGMSFRPLTYNTNGYNWGGYAATGSGFTSVSATWTEPSAKCNSTNDLYAPWVGIDGYGSSSVEQTGVATDCSSGSPVDQAWYEMYPAAPVYLSSSSYPVKAGDVINASVTYSGSNKYKLTLNDSSRGWTYTTTKTLSASRASAEVIIESPTGAYPNFGTLHFTNAKINGGNLSSYNPTALDPSNGPYEAHTSAISGGTSFTDTFEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q824</accession>
    <name>C7Q824_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_5332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015793920.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5332"/>
    <dbReference type="EnsemblBacteria" id="ACU74191">
        <property type="protein sequence ID" value="ACU74191"/>
        <property type="gene ID" value="Caci_5332"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5332"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="OMA" id="IFSFYWK"/>
    <dbReference type="OrthoDB" id="1074175at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="93"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU74191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="32078" checksum="EC6FDD7EB7BC59A5" modified="2009-10-13" version="1">MATVIPTAPRRAKRRDRKSGVNQAGKQMHGSKLTYVILAVVVLISIFPFYWTILAASTSNTEINKVPPNWLPGGNLFKNFHAALNNVDMGKALVNSLIVSGCVAAGTVMFSTLAGFAFAKLRFRFRSVLLGLTIGTMMVPYQLGIVPLFLLMTKLGWSDHLQSVIFPTLVSAFGVFFMRQYLLNALPDELVEAGRVDGASSLRIFLSVVVPIARPAMAVLGMLTFMASWNDFFWPIVVLTSDNPTVQVAIDNLGSGYVPDESIIMAGTLLGTLPVLAVFIVLGRQIVGGIMQGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8N2</accession>
    <name>C7Q8N2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ordered locus">Caci_1374</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785591.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1374"/>
    <dbReference type="EnsemblBacteria" id="ACU70297">
        <property type="protein sequence ID" value="ACU70297"/>
        <property type="gene ID" value="Caci_1374"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1374"/>
    <dbReference type="eggNOG" id="COG0472">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023982_0_1_11"/>
    <dbReference type="OMA" id="ICSELAI"/>
    <dbReference type="OrthoDB" id="1151822at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU70297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="353" mass="38089" checksum="1F9CADC45D9B336F" modified="2009-10-13" version="1" precursor="true">MRALLYATLIALVCSLAGTPVAIRYFTRRGWGQEIRDELPEMHQVKRGTPTMGGTVIVLSTLVAYFVTKLATMKAPTSSGLLVLFLMAGLGAVGFMDDFIKIVRQRSLGLRARAKLAGQLAVTLTFAVLVLHFRNTAGLTPASENISFLRDIGWLSLGPALFLLWSYVMIAGWSNAVNLTDGQDGLAAGTSVMAFGAYVVIGLWQYGQNCAVSPSQGCYQVRDPLDLAIVAAAVMGACFGFLWWNAAPAQIYMGDTGSLALGGAFAGLAICSRTELLAVLIGGLFLMELLSVVIQVTSFKLRHKRVFLNSPIHHHFEQKEWKEVTITIRFWIIAGLCVALGLGVFYGGFKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8V0</accession>
    <name>C7Q8V0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1442"/>
    <dbReference type="EnsemblBacteria" id="ACU70365">
        <property type="protein sequence ID" value="ACU70365"/>
        <property type="gene ID" value="Caci_1442"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1442"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_17_2_11"/>
    <dbReference type="OMA" id="AFMFGPP"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="167" mass="18541" checksum="8B27FB998AC2EFF2" modified="2009-10-13" version="1">MLQAAWRLYTHGGVEALTTDAVAQEAGVGKGTVYRRFRDKSGLVAALLDDKEKELQLAMISGPAPLGPDGTRAERRVAFVRAYLDYLQAHLDLLLVSETAAPGARYRLGVYQFWKTHLTMLFAEDHDPEFRAYTVLALLDASLVSHLLGDGWAWERIRAGAEAEARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q8Y6</accession>
    <name>C7Q8Y6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">Caci_3400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012787599.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3400"/>
    <dbReference type="EnsemblBacteria" id="ACU72306">
        <property type="protein sequence ID" value="ACU72306"/>
        <property type="gene ID" value="Caci_3400"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3400"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_8_5_11"/>
    <dbReference type="OMA" id="FRDELWI"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014322">
        <property type="entry name" value="RNA_pol_sigma-B/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02980">
        <property type="entry name" value="SigBFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="44"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="5">
        <location>
            <begin position="122"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="208"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU72306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="262" mass="28872" checksum="7F48EAE1A9AB2EC2" modified="2009-10-13" version="1">MNTPAESGDYARERAAARAALVRLRRMAPDDAEYEGLREFVIGEYMSYARYVAGRFRQRGESQADLEQVAYLGLVKAVDNFDPDYGAAFLTYATPMIAGEVRRHFRDTTWDVHVPRRVQENALAVRAAERELTQQLGHAPSAAQIAERLDLSADEVAEAYEASAAHHTASLDVPVAMADGDGASMGELMGDDDPGYDLVVDREALKPLLAELSPRDKRILLMKFFRNMSQAQIGAELGVSQMQVSRLLSQILGRLRDQVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9A7</accession>
    <name>C7Q9A7_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ntox30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5394"/>
    <dbReference type="EnsemblBacteria" id="ACU74253">
        <property type="protein sequence ID" value="ACU74253"/>
        <property type="gene ID" value="Caci_5394"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5394"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_584871_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036689">
        <property type="entry name" value="ESAT-6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029111">
        <property type="entry name" value="Ntox30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15532">
        <property type="entry name" value="Ntox30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140453">
        <property type="entry name" value="SSF140453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ntox30" evidence="2">
        <location>
            <begin position="351"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="467" mass="48743" checksum="5E27E0BDE669878E" modified="2009-10-13" version="1">MVRPSGWDVLGLDGDPTPGVVEAVQALAKEFGDFAHDVEHSWSSLNSFGGDATALSWVGQTAEAFKASFGPLPGRLQKLYISYSEASDALAAYWPKLQAAQNNADSALRQGLDAQADLTRATGTAANAAADLKTAQAGTDPKSTADAQTSHDNAQKALSQAKDRLAALTAQAHQAHNDLQTAAKDCAKALHHSQSDGIHNKHWWQHVGQTLSDIGGKIAQWSGEIGQIAVVLAPVLNGIAILTVEVPGLDVVTASLAGADDLIAETAPEVTAAGLAIKATGDGLQGHWNDLAHDAVYLGASRIGGKGGSEGEDGVPPGAMAAQDESSAAEAAAPDPIPRGPGGGWNTNGRDPSELVPPYARQRPWTPAAPGQGAEDGVEWIWKERDANGDEIGPTIRLRVHSADPTAPAGSNAANGPIYRIQHGAKYQDADGNLHPQGIHNKDSPNYDEDAINDTHIPWPLILKLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9L2</accession>
    <name>C7Q9L2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795909.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7354"/>
    <dbReference type="EnsemblBacteria" id="ACU76181">
        <property type="protein sequence ID" value="ACU76181"/>
        <property type="gene ID" value="Caci_7354"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7354"/>
    <dbReference type="eggNOG" id="ENOG5032V9T">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153937_0_0_11"/>
    <dbReference type="OMA" id="DRGYGYK"/>
    <dbReference type="OrthoDB" id="1880783at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045778">
        <property type="entry name" value="DUF6204"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19707">
        <property type="entry name" value="DUF6204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="117" mass="13173" checksum="5A6B49A7C43D8D2D" modified="2009-10-13" version="1">MNERTFRVMVRGSFDALTEDQRTALLADAAEHDVLNAAFTAEGHLTYDLAMRPFFTFRYLEHGEREEDIAAAGESARTKAEQWLDERGYGYKGLKVSAEDMALMPLAKRQRKAQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9U4</accession>
    <name>C7Q9U4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015795988.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU76263">
        <property type="protein sequence ID" value="ACU76263"/>
        <property type="gene ID" value="Caci_7438"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7438"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_11"/>
    <dbReference type="OMA" id="AWYFARA"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="360" mass="38924" checksum="7F41DDB3336A8BCC" modified="2009-10-13" version="1">MPLDHYRTLGRSGLRVSPFALGAMTFGEDPPGAGSSVTESERILTAYLERGGNFVDTANFYTNGHSEAILGDYFAARPGSREHVVLASKFFGNMYPGDPNGGGAGRGAITAQLEQTLRRMRTDYLDLYWLHQWDRNTPIEETMRTLDDLVRAGKVRYIGFSNVPAWVTAQAQTTALLRGWTPLVALQVEYSLLARTVEGELAPLATDQGMALVPWSPLRNGFLSGKYRRGAAVTDSARANHVGAPDDAQFTVIETVAAIADELSTTSSAVALAWLLARPGAVVPIVGARRLEHLESNLAALDITLDDEQLGRLDKVSAPTLDYPAPMRGPLRAMLQFAGTTVDGEASAVYPPLLADSTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C7Q9Z8</accession>
    <name>C7Q9Z8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785690.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1473"/>
    <dbReference type="EnsemblBacteria" id="ACU70396">
        <property type="protein sequence ID" value="ACU70396"/>
        <property type="gene ID" value="Caci_1473"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1473"/>
    <dbReference type="eggNOG" id="ENOG5032ZDZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142113_1_0_11"/>
    <dbReference type="OMA" id="AHYVRKE"/>
    <dbReference type="OrthoDB" id="1912439at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021400">
        <property type="entry name" value="DUF3039"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11238">
        <property type="entry name" value="DUF3039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="98" mass="10700" checksum="F39713530A1A1D32" modified="2009-10-13" version="1">MSTPTFEPDTDTGGSTIVEERVESDYRYEPGDEERFAHYAERDKIMEASVFGTPLTALCGKVWVPSRDPSRFPVCPECKEIFEGLESGGGDDGDGGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAL7</accession>
    <name>C7QAL7_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_3613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3613"/>
    <dbReference type="EnsemblBacteria" id="ACU72516">
        <property type="protein sequence ID" value="ACU72516"/>
        <property type="gene ID" value="Caci_3613"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3613"/>
    <dbReference type="eggNOG" id="COG2909">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015308_1_0_11"/>
    <dbReference type="OMA" id="VEGHVYR"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="816"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU72516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="884" mass="92882" checksum="FA14D679090BE565" modified="2009-10-13" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAT6</accession>
    <name>C7QAT6_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794138.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5550"/>
    <dbReference type="MEROPS" id="S12.A11"/>
    <dbReference type="EnsemblBacteria" id="ACU74409">
        <property type="protein sequence ID" value="ACU74409"/>
        <property type="gene ID" value="Caci_5550"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5550"/>
    <dbReference type="eggNOG" id="COG1680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035614_3_0_11"/>
    <dbReference type="OMA" id="HGYHAFT"/>
    <dbReference type="OrthoDB" id="1439085at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="364" mass="38726" checksum="719705FCDB213C1A" modified="2009-10-13" version="1">MAEVQGTYTKEFSAVADALSELLDTQDIGASAAVFVDGEPVADVWGGYVDAERTVAWERDTIVNVMSTTKPMTALCALILADRGELDLSAPVSTYWPEFAAAGKDGVLVRHLLSHTAGLPDWPGRLVAEDLYDWSAVTDRLAAMPTQWEPGTAAGYHSVTFGFLVGEVVRRVSGRSIGRFLAEEVAGPLGADFHIGLGAQDDARIARLYAPPSQSDEFASSGPEYESVGGIRVKDANTEAWRRAEVPAANGFGNARGIARAQSALSNRGVAGGVRLLSEKGCEPAWHAEYSGEDRVLGQPTTYGVGFGVFGGTFGWGGWGGSLVMNDHASRMTVAYAMNQMLDPREQDDSRGLRIVSAAYEGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QAU2</accession>
    <name>C7QAU2_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NUDIX hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_5556</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794144.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5556"/>
    <dbReference type="EnsemblBacteria" id="ACU74415">
        <property type="protein sequence ID" value="ACU74415"/>
        <property type="gene ID" value="Caci_5556"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5556"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_21_2_11"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU74415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="130" mass="14135" checksum="222BDB68C57492FB" modified="2009-10-13" version="1">MEIVHEVAIVVLTDPAGRVLMQHRGHDADVEPDRWTPPGGHLEPGEDAMTAACRELLEETGLTAVLQPGRVVERVDAAGAGVRFHVFTGRTDARQEDVILGEGQAMRFLTLDEIAIKELVSNADLFLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBE0</accession>
    <name>C7QBE0_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 42 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1596"/>
    <dbReference type="EnsemblBacteria" id="ACU70517">
        <property type="protein sequence ID" value="ACU70517"/>
        <property type="gene ID" value="Caci_1596"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1596"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011983_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002982982" evidence="1">
        <location>
            <begin position="34"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42" evidence="2">
        <location>
            <begin position="84"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="778" mass="81627" checksum="7A669E2D84BC9900" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBH8</accession>
    <name>C7QBH8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_1634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012785849.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1634"/>
    <dbReference type="EnsemblBacteria" id="ACU70555">
        <property type="protein sequence ID" value="ACU70555"/>
        <property type="gene ID" value="Caci_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1634"/>
    <dbReference type="eggNOG" id="ENOG5032Z7M">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109360_1_0_11"/>
    <dbReference type="OMA" id="WRSYKAD"/>
    <dbReference type="OrthoDB" id="1905807at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021443">
        <property type="entry name" value="DUF3093"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11292">
        <property type="entry name" value="DUF3093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU70555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="149" mass="15741" checksum="2B23793B71546C48" modified="2009-10-13" version="1">MAGKDSTYEERLTAPAGWWAVTVMAGVMGGLVFLRVSPVAALVAAIVTAALGAALVVAYGRIAVRVQDGYLEAGPARLPLTALGAATALDAEAARRLRTTEADARAFILLRGYVTTAVRVDVTDPEDPTPYLYLSTRRPDKLVKVLSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBN9</accession>
    <name>C7QBN9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_1695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1695"/>
    <dbReference type="EnsemblBacteria" id="ACU70616">
        <property type="protein sequence ID" value="ACU70616"/>
        <property type="gene ID" value="Caci_1695"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1695"/>
    <dbReference type="eggNOG" id="ENOG5032BQI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117206_0_0_11"/>
    <dbReference type="OMA" id="PWHLAAH"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU70616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="211" mass="22540" checksum="8BAA08896A4B13E6" modified="2009-10-13" version="1">MNPMDAEQTTFLRELVSGTPWFGECRGFARTLRRAPRSPGGLLLVGTPEEEPWHLAAHLDTEAGLANLPQLAPTLIRHQIPDGAPPHLAVPLARLEQARKGEAVFIVAPDDPGTPLLERVDDARRRGAAILTLAEDEETSSELLTLSHDALLVPENGIVPGFDAAQHLLASTAGEGEGRKGGRGSGPRLGFRDRLTALIDQVSGGSADTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBT3</accession>
    <name>C7QBT3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3650"/>
    <dbReference type="EnsemblBacteria" id="ACU72552">
        <property type="protein sequence ID" value="ACU72552"/>
        <property type="gene ID" value="Caci_3650"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3650"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096355_0_0_11"/>
    <dbReference type="OMA" id="GIRFQAI"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="249" mass="25492" checksum="A682CCF684F5E390" modified="2009-10-13" version="1">MPTQDLSGTTALVTGATKGFGRAVAAALVASGARVVAVARDQEALAGLTEEFGSAVVPVQADVADPVSAGRLLGEYRPRTVVLNAGTNPLARPLQMHTWESFSRPFEVDVKQAFHWSREALLLPLEPGSTVVAVSSGAAINGSPLSGGYAGAKATVRFVSSYAAGEAERAGLGIRFVSVLPMMSPLTAVGANGAAAYAARQGVPLAAFLERMGPPLTPEHVGKAILDIASDTSFDQPAYLLKPTGPAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QBZ5</accession>
    <name>C7QBZ5_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">Caci_3712</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3712"/>
    <dbReference type="CAZy" id="CBM51">
        <property type="family name" value="Carbohydrate-Binding Module Family 51"/>
    </dbReference>
    <dbReference type="CAZy" id="GH35">
        <property type="family name" value="Glycoside Hydrolase Family 35"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72614">
        <property type="protein sequence ID" value="ACU72614"/>
        <property type="gene ID" value="Caci_3712"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3712"/>
    <dbReference type="eggNOG" id="COG1874">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005732_2_0_11"/>
    <dbReference type="OMA" id="PEFEGGW"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018905">
        <property type="entry name" value="A-galactase_NEW3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_dom4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10633">
        <property type="entry name" value="NPCBM_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00776">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="SSF117100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002983102" description="Beta-galactosidase" evidence="9">
        <location>
            <begin position="38"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="domain" description="BetaGal_dom2" evidence="11">
        <location>
            <begin position="563"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM" evidence="10">
        <location>
            <begin position="1246"/>
            <end position="1391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACU72614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="1392" mass="145968" checksum="1E9285349C16C8E3" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QC56</accession>
    <name>C7QC56_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Large conductance mechanosensitive channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794233.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5645"/>
    <dbReference type="EnsemblBacteria" id="ACU74504">
        <property type="protein sequence ID" value="ACU74504"/>
        <property type="gene ID" value="Caci_5645"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5645"/>
    <dbReference type="eggNOG" id="COG1970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095787_2_3_11"/>
    <dbReference type="OMA" id="RMQEFAN"/>
    <dbReference type="OrthoDB" id="1863650at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="174" mass="18560" checksum="124F713C4445B2EC" modified="2009-10-13" version="1" precursor="true">MNGFVKFVVRGNVIGLAVGVVIGAAFAAMVTSFTTAFLTPLIGWATGGIGDYSKKVFTLGKTPFPYGTFVNAGISFLLTAATLYFLIVLPVNKLTEELNPHHDLSHAKRSCPECLQQIPARARRCSYCTSTVAPILDEDSPDLTDELPGEIALRSALPEMRFGEPAAAAEAKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCA9</accession>
    <name>C7QCA9_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Pyruvate kinase</fullName>
            <ecNumber evidence="5 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">Caci_5699</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 14"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794286.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5699"/>
    <dbReference type="EnsemblBacteria" id="ACU74557">
        <property type="protein sequence ID" value="ACU74557"/>
        <property type="gene ID" value="Caci_5699"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5699"/>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_2_11"/>
    <dbReference type="OMA" id="QVPIVQK"/>
    <dbReference type="OrthoDB" id="1098983at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 17" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="15">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="16">
        <location>
            <begin position="364"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ACU74557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="493" mass="52561" checksum="EA4BD5D2591AA4C6" modified="2009-10-13" version="1">MRRAKIVCTLGPSAGSLEQLTALVDAGMNVARLNLSHGSYEDHEERYRNVRQVATTSGQAIGILVDLQGPKIRLGTFANGKEVLANGAQFTITTRDVAGDATICGTTYKGLPGDCRPGDQILVDDGKLCLEVQSVTDTDVVTRVVEGGPISNSKGINLPGVSVSVPALSEKDELDLRWALGKPETGHGNPGVRADMIALSFVRDAVDIERVHEIMDEIGHRVPVIAKIEKPQAVANLDAIVDAFDAIMVARGDLGVELPLEQVPMVQKRCITLSRRNAKPVIVATQMLDSMITNSRPTRAEVSDVANAVLDGTDAVMLSAETSVGAYAVQTVETMAKIITAAEEETLAAGLKPALSKPRTKGGAVARAAAELSENLYAKYLVAFTESGDTARRLSRYRPPTPLIAFTPHNEIRNQLALSWGIRTFCSPEVEHTDDMVRQVDTELLQLELSKTGDTVVIIAGSPPGIPGSTNAVRVHRVGDAINGVVPAYRAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-04-07" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCI4</accession>
    <name>C7QCI4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_7623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796172.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7623"/>
    <dbReference type="EnsemblBacteria" id="ACU76447">
        <property type="protein sequence ID" value="ACU76447"/>
        <property type="gene ID" value="Caci_7623"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7623"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902218_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU76447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="308" mass="34176" checksum="78F9DDABD4936819" modified="2009-10-13" version="1">MTDPELTVIVPTRERPGLLKETVESIVASARAASDKLGATVRVLVVDDASPTESTREAVAALTAETAAAGTAVSVDYARVEVHDGRKDPGAAIALGVSQATSRYLTIFGDDDIMLPEHITLHLQNMRRGADVSAASYFITDGQLNRQHAKRRRAAHLGDLLIGRIDVNDGAFVRTELIQAVELDPALLAQMLYPVWATLLIDKRKFVYSRTPTFLYRRHDANISSVNKNAEDAALRTSLQEKYQALASEKLGAVPEPRKVDWARHKREWQYSKKGYVRWRMAATELAVKRNPVVRKAFRMPPLPPKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QCQ2</accession>
    <name>C7QCQ2_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH-quinone oxidoreductase subunit A</fullName>
            <ecNumber evidence="6">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NADH dehydrogenase I subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">NDH-1 subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">NUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nuoA</name>
        <name evidence="8" type="ordered locus">Caci_7691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cell membrane</location>
            <topology evidence="6 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the complex I subunit 3 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796240.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7691"/>
    <dbReference type="EnsemblBacteria" id="ACU76515">
        <property type="protein sequence ID" value="ACU76515"/>
        <property type="gene ID" value="Caci_7691"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7691"/>
    <dbReference type="eggNOG" id="COG0838">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119549_0_0_11"/>
    <dbReference type="OMA" id="RFPVKYY"/>
    <dbReference type="OrthoDB" id="1748431at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01394">
        <property type="entry name" value="NDH1_NuoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023043">
        <property type="entry name" value="NAD(P)H_OxRDtase_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000440">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038430">
        <property type="entry name" value="NDAH_ubi_oxred_su3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11058">
        <property type="entry name" value="PTHR11058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00507">
        <property type="entry name" value="Oxidored_q4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="6 7" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACU76515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="119" mass="13437" checksum="781D6143A85A6BC5" modified="2009-10-13" version="1" precursor="true">MNSYAPILVLGGLAAGFAVFSVVSGMLTGPKRYNRAKLEAYECGIEPTPQPVGGGRFPVKYYLTAMLFIIFDIEIVFLYPWAVRFDSLGWFGLVEMVFFILTVFVAYAYVWRRGGLEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>C7QD58</accession>
    <name>C7QD58_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_1848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_1848"/>
    <dbReference type="EnsemblBacteria" id="ACU70768">
        <property type="protein sequence ID" value="ACU70768"/>
        <property type="gene ID" value="Caci_1848"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_1848"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1871677_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU70768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="136" mass="14827" checksum="341B594B2BC970B6" modified="2009-10-13" version="1">MDPYIPIQMYRRFGSGPPTDHSPVSEPPVPPRQDPGQPWRAEGRPPEKPGPPNKPQRGPNVPGGWPRLLLTMLLVFLVTDLLLSLFNAGASSSKVPYTEFTKQVAANNVKDVYSKGDAIQGDLKEKAPVPDDGDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDA8</accession>
    <name>C7QDA8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">Caci_3799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3799"/>
    <dbReference type="EnsemblBacteria" id="ACU72701">
        <property type="protein sequence ID" value="ACU72701"/>
        <property type="gene ID" value="Caci_3799"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3799"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OMA" id="LWAHRTV"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACU72701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="256" mass="27429" checksum="06B26CD36BD6C8D5" modified="2009-10-13" version="1">MTGTPLVRIRGLKKSFGAHRVLDGIDLDVREGEVTVLLGPSGSGKSTLLRCVNHLERPDAGFVEIGGDIIGYRHDGGGKLHELHGKTVTRQRAQVGMVFQQFNLFPHLTVLENLIEAPVSVRGLAKADAVNRAVDLLARVGLAGREGSYPRHLSGGQQQRVAIARALAMEPRVLLFDEPTSALDPELVGEVLAVIRDLAHSGMTMIVVTHEIGFAREVADTAVFLDGGRIVESGAPAAVLDHPTHDRARAFLSAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDF8</accession>
    <name>C7QDF8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU72751">
        <property type="protein sequence ID" value="ACU72751"/>
        <property type="gene ID" value="Caci_3856"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3856"/>
    <dbReference type="HOGENOM" id="CLU_1203060_0_0_11"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="230" mass="24359" checksum="EEE1E39CCB947168" modified="2009-10-13" version="1">MGFGRGGRVSKEEVSEALEAVAAHRSELAGLGSLPDGLQETVLQMLPLGTRLALETYNLVDVSPVTSRSVQILRLNPLGKAVLKQLKKGDDPAPSSLDELLEEDADQEVALVGLTPVTVRVEQVRGWRDSVAEDSPFTEWQDVSEGPVPVAVEVGEELAATVVAHLALEKAGSTVVVWQESGLASVIDRRTGEPLPHRDRPLAIAALDETIEAVESRLAVAPNPSGSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDR1</accession>
    <name>C7QDR1_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_5827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5827"/>
    <dbReference type="EnsemblBacteria" id="ACU74685">
        <property type="protein sequence ID" value="ACU74685"/>
        <property type="gene ID" value="Caci_5827"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5827"/>
    <dbReference type="eggNOG" id="COG3629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_0_1_11"/>
    <dbReference type="OMA" id="RITEMLM"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACU74685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="264" mass="28380" checksum="59F8F73C3AA020E5" modified="2009-10-13" version="1">MIDIAVLGTVQTVVRSGLRTTPVGLSYLERSLMATLACTPGRVVSVGRLVEVLWEDAPPTGARTRVQGLVSSLRKRLAAAGGQSGTLATDPGGGYLLRVAPGCVDAERFRSLIHQASAQTERGTPGCAASTWQSALALWRGPAFDGLRSYLLQAEALRLEEMRMTALEHCLSADLHAGRHEHAIPELSRLSALHPGRERLVGQLMIALNAVDRHAEALGAYRALQLYLREQYGTSPGPRLRRIHELMLRAPVGDGELLAALTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDT8</accession>
    <name>C7QDT8_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">Caci_5854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794441.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5854"/>
    <dbReference type="EnsemblBacteria" id="ACU74712">
        <property type="protein sequence ID" value="ACU74712"/>
        <property type="gene ID" value="Caci_5854"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5854"/>
    <dbReference type="eggNOG" id="COG3833">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OMA" id="NTYLMYG"/>
    <dbReference type="OrthoDB" id="1510342at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACU74712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="281" mass="30226" checksum="EAE641373D175D25" modified="2009-10-13" version="1" precursor="true">MMKDRLWWRHLIGLAALVFALVPILFLVSAALNPVGTLSTTSLIPTGASLSNFSKLFHDPNSPYVRWYVNTLVICGVSAVLNVLIGVSGAYAFSRLRFRGRRPGLTGILLVQMFPNFISLTALYLTFISIGDVLPAAGLNTSLGLILVYLGGAMGVNTWLLKGYLDTIPKELDEAARIDGATENQVFFRVILPLAVPMLVVVGLFSFVSFLNEILLAGVFLTDTTHKTLAVGLYGLVSGNHNTDYGEFAAGSLLAGVPVVLIYLYLQKYLVKGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDY4</accession>
    <name>C7QDY4_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_7748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015796297.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7748"/>
    <dbReference type="EnsemblBacteria" id="ACU76572">
        <property type="protein sequence ID" value="ACU76572"/>
        <property type="gene ID" value="Caci_7748"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7748"/>
    <dbReference type="eggNOG" id="COG3193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103773_2_1_11"/>
    <dbReference type="OMA" id="RMDDAWV"/>
    <dbReference type="OrthoDB" id="1551899at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU76572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="133" mass="13217" checksum="62341424DDEEC2E8" modified="2009-10-13" version="1">MSTLNLETTARIVAAGREAATGIGVAMSIAIVDPAGNLVEFQRMDGAWLGSVDIAQRKARTSALFPMPSSVLGEMSQPGGPIYGIETSNGGLVSFGGGFPLAAADGTVIGAVGVSGGLVEQDVAVAEAVVKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>C7QDZ8</accession>
    <name>C7QDZ8_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ordered locus">Caci_7762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU76586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_7762"/>
    <dbReference type="EnsemblBacteria" id="ACU76586">
        <property type="protein sequence ID" value="ACU76586"/>
        <property type="gene ID" value="Caci_7762"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_7762"/>
    <dbReference type="eggNOG" id="COG0743">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035714_4_0_11"/>
    <dbReference type="OMA" id="PIDSEHF"/>
    <dbReference type="OrthoDB" id="1200722at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="8"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="158"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="274"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACU76586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="407" mass="42571" checksum="D5C582BEAD48F3DC" modified="2009-10-13" version="1">MTHTVRDIILLGSTGSIGTQTLDLVARNPDRFRIVGLAAGGGNPELLAEQALATGARTVAVAKGSAAQDLNLAFYASAKKRGYSAGEFQIPEILAGPDAATELAARACDIVLNAIDGAAGLKATLAALDAGRTLALANKESLIIGGDLVARRAKPGQIVPVDSEHSALAQALRGGRAEEVEKLIVTASGGPFRGRTRAEMADVSPEQAMKHPTWTMGPLVTCNSSTLVNKGLEVIEAHLLFDVPFERIEVVVHPQSIVHSMVQFVDGSTLAQASPPDMRLPIALALGWPDRIPGAAPAIDWTKASTWEFFPLDDEAFPSVRLAKQVGATGGTAPAVFNGANEECVAAFLAGRLRFPAIVDTIERVVAEHAGSARSQGGDLTLEAVLEADSWARTRARELTTGGQTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2020-10-07" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEP5</accession>
    <name>C7QEP5_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">Caci_3931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU72815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_3931"/>
    <dbReference type="EnsemblBacteria" id="ACU72815">
        <property type="protein sequence ID" value="ACU72815"/>
        <property type="gene ID" value="Caci_3931"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_3931"/>
    <dbReference type="eggNOG" id="COG3620">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029927_5_0_11"/>
    <dbReference type="OMA" id="AFDLGHW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACU72815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="445" mass="47756" checksum="B81EE57C61158309" modified="2009-10-13" version="1">MPEGEPTALRVLVVERRWRTYETFRRHFEEAARALAAETNDPRMAALSVSRTQFERWLRGGLTTRPYPNASTVLQRMFSVEVDVLLGPASEANLQEPAQAFNLKSEITMAAHESSEHAAYAAARAVDDTTIEQLQEDVAKVAREYPEKAPIESFAEAKRIRDLALSLLDRTGRPAQESELYVAAGQACGILATVSFDLGYTDAASEQARTVFIYGRMVGNEGLCAWAMGMRALIANWSEFPLAALELVAKGLATAPAGTPTARLHAIGARAYAQLGNAASASESARLALSAADSDSPACELHDDIGGEFSFDGARLRRCLGSAYVSLKLAEPAAQHARQVIELYDTGARIVRMPKVAVEARIELAHALILSGELDSATDTLGTVFDLAQPQRVHGVTERLVKARQALALPAYQGSSEALDLGARIEAFAAGSAGAIAPALPPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>C7QEY9</accession>
    <name>C7QEY9_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794476.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5889"/>
    <dbReference type="EnsemblBacteria" id="ACU74747">
        <property type="protein sequence ID" value="ACU74747"/>
        <property type="gene ID" value="Caci_5889"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5889"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0406">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035712_0_0_11"/>
    <dbReference type="OMA" id="GRWQIKH"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014636">
        <property type="entry name" value="RNaseH/PGlycerate_mutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036922">
        <property type="entry name" value="RNaseH_PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="427" mass="44261" checksum="365DC5D4466E8BAE" modified="2009-10-13" version="1">MARTFIVEADGASRGNPGPASYGALVADAATGEVLAELAEGLGVVTNNVAEYRGLIAGLRAAYALDPHAEVEVRMDSKLAVQQMSGVWQVKHPDIKQLAVQARTAFPQAGAVRYTWVPRAENKRADALANLALDDPAAAAAKMAEAEVMTAAFRAARAAREAGGGDGSGGEGGAAAAAASQQEALPGISENTAAEAAVTTSSSSNPAPSSYQQPSWSPAPDMGPPTTLLLLRHGATALTAEKRFSGAGDPELSAVGLQQVDAVARRLAARGGVDAIVASPLGRTVQTAQAAADALGLPVEIDPGFRETDFGLWDGYSFAEVRERWPAEHRAWLASTAVAPPQGESFDAVADRVLAARDDLIARYARRTVLVVSHVTPIKTLIRDALGAPPESLYAMELSAASLSVLTCYSDGRASMRLFNDTAHLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2021-06-02" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF04</accession>
    <name>C7QF04_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">Caci_5904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_015794491.1">
        <property type="nucleotide sequence ID" value="NC_013131.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ACU74762">
        <property type="protein sequence ID" value="ACU74762"/>
        <property type="gene ID" value="Caci_5904"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5904"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_8_11"/>
    <dbReference type="OMA" id="ARYHEEY"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="40"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACU74762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="172" mass="19138" checksum="6E3BEE003BFF4E6B" modified="2009-10-13" version="1">MKYLTTAHPDVEHETAPAYRGTVSRADLPAALDNRRDPVTAEVLELFWAASQSFYDNYDEAAARHDLTRMQAFVLANLMAGPKPMRFLAEHLKCEPSNITGLVDRMEARGLVTREPDPEDRRVKRITATELGRASFDAVWSGLTFAAEPLAGLSGSERETLRDLLRRIVPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>C7QF61</accession>
    <name>C7QF61_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cholesterol oxidase</fullName>
            <ecNumber evidence="3">1.1.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">Caci_5961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU74819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_5961"/>
    <dbReference type="EnsemblBacteria" id="ACU74819">
        <property type="protein sequence ID" value="ACU74819"/>
        <property type="gene ID" value="Caci_5961"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_5961"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040036_0_0_11"/>
    <dbReference type="OMA" id="GRANHMW"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016995">
        <property type="term" value="F:cholesterol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002980924" evidence="1">
        <location>
            <begin position="43"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="484"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACU74819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="546" mass="58113" checksum="559FE657C24B6DE1" modified="2009-10-13" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFR1</accession>
    <name>C7QFR1_CATAD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_0045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU69000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_0045"/>
    <dbReference type="EnsemblBacteria" id="ACU69000">
        <property type="protein sequence ID" value="ACU69000"/>
        <property type="gene ID" value="Caci_0045"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_0045"/>
    <dbReference type="eggNOG" id="COG0652">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_11"/>
    <dbReference type="OMA" id="ELYNDHA"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU69000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="193" mass="21319" checksum="A87BED4A24B59A38" modified="2009-10-13" version="1">MTETERQQTVAENLYATIKTNHGDIVVRLLPDYAPKTVANFVGLAEGTREWTHPETNVTSTTPLYDGTIFHRIIPQFMIQGGDPLGQGFGGPGYVFDDEPHPDQTFNDRDYLLAMANAGIRNGKGTNGSQFFITVPTPRRPTHLNGKHTIFGEVVDADSRKVVDEIAGVRTGAQDRPVNDVVIEKISIERREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>C7QFX3</accession>
    <name>C7QFX3_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">Caci_2030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
                <person name="Eisen J.A."/>
                <person name="Markowitz V."/>
                <person name="Hugenholtz P."/>
                <person name="Kyrpides N.C."/>
                <person name="Klenk H.P."/>
            </authorList>
            <dbReference type="PubMed" id="21304647"/>
            <dbReference type="DOI" id="10.4056/sigs.17259"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001700">
        <property type="protein sequence ID" value="ACU70950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="479433.Caci_2030"/>
    <dbReference type="EnsemblBacteria" id="ACU70950">
        <property type="protein sequence ID" value="ACU70950"/>
        <property type="gene ID" value="Caci_2030"/>
    </dbReference>
    <dbReference type="KEGG" id="cai:Caci_2030"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OMA" id="QWTGYNA"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000851">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="45"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACU70950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000851"/>
        </source>
    </evidence>
    <sequence length="297" mass="33297" checksum="8452DBF263F6F8D9" modified="2009-10-13" version="1" precursor="true">MFFFAYPLGASLYQSFTTDDSGTQSWAGLAQYRRMLHDPIFWKSLWNTGLLLIFQVPLMIGLALVLACVLNQSWMRFKGTWRVAFFLPSVTMLVAYAVVFRVLLKTDGGMVNQVLGWVGISPVDWLNNPVWARVALIGTITWRWTGYNAVILLAGLQSIPREQYEAAAIDGAGAVTTFRKVVVPQLRPVILFCSITSTIGTLQLFDENFVLTKGGPDNATMTPVLYLYKVGFDQMDFSYASAIAWAVVLIIGVLSVVQFRFFGQADRDASTARSQGMQKTHKTHKTQRTRRTQRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-10-13" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>C7QG27</accession>
    <name>C7QG27_CATAD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate reductase/succinate dehydrogenase flavoprotein domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">Caci_2085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)</name>
        <dbReference type="NCBI Taxonomy" id="479433"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Catenulisporaceae</taxon>
            <taxon>Catenulispora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Stand. Genomic Sci." volume="1" first="119" last="125">
            <title>Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).</title>
            <authorList>
                <person name="Copeland A."/>
                <person name="Lapidus A."/>
                <person name="Glavina Del Rio T."/>
                <person name="Nolan M."/>
                <person name="Lucas S."/>
                <person name="Chen F."/>
                <person name="Tice H."/>
                <person name="Cheng J.F."/>
                <person name="Bruce D."/>
                <person name="Goodwin L."/>
                <person name="Pitluck S."/>
                <person name="Mikhailova N."/>
                <person name="Pati A."/>
                <person name="Ivanova N."/>
                <person name="Mavromatis K."/>
                <person name="Chen A."/>
                <person name="Palaniappan K."/>
                <person name="Chain P."/>
                <person name="Land M."/>
                <person name="Hauser L."/>
                <person name="Chang Y.J."/>
                <person name="Jeffries C.D."/>
                <person name="Chertkov O."/>
                <person name="Brettin T."/>
                <person name="Detter J.C."/>
                <person name="Han C."/>
                <person name="Ali Z."/>
                <person name="Tindall B.J."/>
                <person name="Goker M."/>
                <person name="Bristow J."/>
      